Abstract: A newborn respiration monitoring system includes a flow sensor that measures a gas flow and a CO2 sensor that measures a CO2 within the breathing circuit for an infant. The system further includes a resuscitation module executable on a processor of a computing system to receive the flow measurement and the CO2 measurement and determine respiratory information for the infant. A digital display is communicatively connected to the computing system and displays the respiratory information.

Abstract: A breath capturing device including a body having an internal reservoir, an inlet, a first outlet, and a second outlet. A first pathway extends between the inlet and the reservoir, a second pathway extends between the reservoir and the first outlet, and a third pathway extends between the reservoir and the second outlet. A first valve is positioned within the first pathway and is configured to restrict flow therealong to flow from the inlet to the reservoir above a first pressure. A second valve is positioned within the second pathway and is configured to restrict flow therealong to flow from the reservoir to the first outlet above a second pressure greater than the first pressure. A third valve is positioned within the third pathway and is selectively transitional between an open and closed configurations to selectively retrieve fluid from the reservoir.

Abstract: A early detection device to diagnose scoliosis in adolescents without exposure to harmful x-rays provides a portable, accurate and inexpensive hand-held diagnostic tool to determine deviations from the Cobb Angle in the spine, the detection device connecting to a receiver unit to receive data obtained from the detection device completing the diagnostic testing for visual review and diagnosis on the receiver unit. It is also provided in alternative embodiment to test the integrity of structural components in various industries, including surface irregularities and defects and cracks in beams and wall, pipes or beams.

Abstract: Disclosed herein is an anthropometric device. The device includes a base, an upstanding member and a measuring member for measuring one or more anthropometric parameters. The upstanding member has a first end and a second end with the first end secured to the base. The measuring member is suitably connected to the upstanding member. The measuring member has distal ends, the distal ends are extendable relative to first measuring member.

Abstract: One aspect of the present disclosure relates to a system for monitoring a diaphragmatic twitch response. The diaphragmatic twitch response can be used to determine a depth of neuromuscular blockade. The system includes a neural stimulation device to stimulate a phrenic nerve of a subject, which has the effect of stimulating the subject's diaphragm. The system also includes a monitor to detect the diaphragm's response to the stimulation. For example, the monitor can include a nasogastric tube with two distally positioned inflatable balloons. Each of the inflatable balloons is coupled to a sensor to measure a corresponding pressure (e.g., an esophageal pressure and a gastric pressure). The pressure differential between the esophagus above the diaphragm and the stomach below the diaphragm (also referred to as the transdiaphragmatic pressure) can be used as a measure of the diaphragmatic twitch response.

Abstract: An inertial sensor based surgical navigation system for knee replacement surgery is disclosed. Inertial sensors composed of six-degree-of-freedom inertial chips, whose measurements are processed through a series of integration, quaternion, and kalman filter algorithms, are used to track the position and orientation of bones and surgical instruments. The system registers anatomically significant geometry, calculates joint centers and the mechanical axis of the knee, develops a visualization of the lower extremity that moves in real time, assists in the intra-operative planning of surgical cuts, determines the optimal cutting planes for cut guides and the optimal prosthesis position and orientation, and finally navigates the cut guides and the prosthesis to their optimal positions and orientations using a graphical user interface.

Abstract: A method is provided which includes providing a sensor operable to measure movement over time on a user. The sensor includes an alert unit. The sensor is configured with a threshold to activate the alert unit when the measured movement over time is below the threshold. The measurements of movement over time are obtained, and it is determined whether the measured movement over time is below the threshold. When the measured movement is below the threshold, the alert unit at the sensor is activated to alert the user.

Abstract: A method includes obtaining rotational data and translational data for a joint, the rotational and translational data being indicative of rotational and translational movement of the joint during rotational and translational joint testing, respectively, the rotational and translational joint testing being implemented by a robotic testing apparatus applied to the joint. A quantity indicative of joint play of the joint is computed. The quantity is computed via a function of the rotational data and the translational data. The method includes determining whether the computed quantity exceeds a joint play threshold and, if the computed quantity exceeds the joint play threshold, comparing the rotational data and the translational data with preset rotational data and preset translational data for the rotational and translation joint testing, respectively.

Abstract: Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.

Abstract: A device for in vivo detecting and quantifying a concentration of an analyte in a peritoneal fluid of a subject. The device includes (a) a catheter having an open proximal end configured to be disposed external to the subject, an open distal end configured to be disposed within the peritoneal cavity comprising the peritoneal fluid, an anchor portion, an outer wall, and an inner wall, (b) a sensor disposed adjacent to the open distal end and configured to detect and quantify the concentration of the analyte in the peritoneal fluid, and (c) a main control unit disposed external to the subject, connected to the sensor via a wire, and configured to control the sensor, receive and store detection and quantification data from the sensor, and transmit the data to a second device. A portion of the wire is disposed between the inner wall and the outer wall of the catheter.

Abstract: Methods and apparatus for providing a power supply to a device, including an inductive rechargeable power supply for a data monitoring and management system in which a high frequency magnetic field is generated to provide power supply to a rechargeable power source such as a battery of a transmitter unit in the data monitoring and management system are provided.

Abstract: A wearable monitoring system includes a first flexible substrate encapsulating a current ramping system to provide a current to an electrode in direct contact with a predetermined location of skin of a user to promote bodily fluid secretion, and a second flexible substrate placed over the predetermined location, the second flexible substrate having an integrated electrochemical sensor to determine bodily fluid concentration levels secreted through the skin.

Abstract: The present invention relates to an electrode assembly (eg a nanoelectrode assembly), to an electrochemical glucose biosensor comprising the electrode assembly and to an apparatus for combating (eg management of) diabetes mellitus which comprises the electrochemical glucose biosensor.

Abstract: Methods, devices and systems for receiving an instruction to determine a glycemic variation level, retrieving a stored metric for determining the glycemic variation level, retrieving one or more parameters associated with the retrieved metric analysis, determining the glycemic variation level based on the retrieved one or more parameters for the retrieved metric analysis, and outputting the determined glycemic variation level when it is determined that the retrieved one or more parameters associated with the retrieved metric analysis meets a predetermined condition are disclosed.

Abstract: A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector.

Abstract: Enzymatic and non-enzymatic detectors and associated membrane apparatus, and methods of use, such as within a fully implantable sensor apparatus. In one embodiment, detector performance is controlled through selective use of membrane configurations and enzyme region shapes, which enable accurate detection of blood glucose level within the solid tissue of the living host for extended periods of time. Isolation between the host's tissue and the underlying enzymes and reaction byproducts used in the detectors is also advantageously maintained in one embodiment via use of a non-enzyme containing permeable membrane formed of e.g., a biocompatible crosslinked protein-based material. Control of response range and/or rate in some embodiments also permits customization of sensor elements. In one variant, heterogeneous detector elements are used to, e.g., accommodate a wider range of blood glucose concentration within the host.

Abstract: Embodiments of the invention provide compositions useful in analyte sensors as well as methods for making and using such compositions and sensors. In typical embodiments of the invention, the sensor is a glucose sensor comprising an analyte modulating membrane formed from a polymer composition having carbonate and aromatic isocyanate chains, a composition observed to provide such membranes with improved material properties such as enhanced thermal and hydrolytic stability.

Abstract: A skin pricking device includes a housing having an opening formed in a proximal end thereof; a spring mounted lancet including a needle within a casing having body and cap parts, interconnected by a separable coupling. The cap part has a cap projecting through the opening allow a user to grip and remove the cap. The device further includes a trigger for firing the lancet. Turning the cap part moves the entire lancet, engaging a trigger stop surface on the distal body part of the lancet with a trigger catch and further biasing the trigger to block the lancet. Further turning of the cap part over a second angle relative to the housing causes the cap part to move in a proximal direction by a further, second distance, thereby axially separating the cap part from the body part, whereby the cap part can then be removed from the device.

Abstract: A sample collection device for a fluid includes: a substantially disk-shaped body having a periphery; a capillary channel extending through the body and bounded by the periphery, having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; a sample collection well located in the vicinity of the second end and in fluid communication with the capillary channel; and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the major surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a housing comprising an air vent in fluid communication with the capillary channel when the disk is rotated in a first position.

Abstract: Embodiments herein include systems and methods for detecting, predicting and/or assessing acute kidney injury. In an embodiment, a monitoring system to detect acute kidney injury is included. The monitoring system can include a sensor circuit configured to collect renal data including at least one of systemic renal data, direct renal data, urinary tract data, and renal-relevant extracorporeal data. The monitoring system can also include a memory circuit to store collected renal data, an evaluation circuit to assess renal status, and a telemetry circuit. The evaluation circuit can determine whether acute kidney injury has occurred or is likely to occur by comparing the renal data to at least one of threshold values, personal historical values, patient population values and patterns indicative of acute kidney injury. The evaluation circuit can initiate a warning notification if acute kidney injury has occurred or is likely to occur. Other embodiments are also included herein.

Abstract: A portable biomedical device for detecting ischemic stroke in the brain. Its unique capability of enabling portability and compactness and being able to accommodate software that can resolve blood flow velocity measurements enable us to leverage multi-modality system benefits while using simple single modality instrumentation. This unique device provides an ideal diagnostic and predictive tool for ischemic attack such as TIA; not only at hospital bedside but also in a home environment.

Abstract: There is provided a method for use in determining whether a subject is allergic to a substance.

Abstract: A method, apparatus and system for processing acquired skin texture data, wherein the method for processing acquired skin texture data comprises: acquiring Qi and Blood state information by triggering a Qi and Blood information acquisition step (101a) in a skin texture area, acquiring skin tone state information by triggering a skin tone information acquisition step (101b), acquiring skin elasticity information by triggering a skin texture information acquisition step (101c), acquiring skin moisture information by triggering a skin moisture information acquisition step (101d), and acquiring luster and gloss information by triggering a skin gloss information acquisition step (101e); and comparing the acquired skin tone state information, skin elasticity information, skin moisture information and luster and gloss information with pre-set indicator intervals, and determining the overall skin texture state of the skin texture area in combination with the Qi and Blood state information (102).

Abstract: The disclosure describes a smart bandage assembly. The bandage assembly includes a bandage member; a movement sensor, a pressure sensor, a methane sensor, or a humidity sensor; a microcontroller; a memory; and a radio transceiver for communication with a mobile communications device. The electronic components of the bandage assembly may be embedded within the bandage member. In some implementations, the radio transceiver harvests RF energy to power the memory within the bandage assembly so that sensor data stored in the memory can be accessed by a mobile communications device when other remaining electronic devices in the bandage assembly remain in a sleep state or power off mode.

Abstract: A pair of stimulating electrodes and a mechanomyography sensor come into intimate contact with a body surface of a muscle, appearing on a back surface of an insulating sheet and being spaced a predetermined distance apart; accordingly, an electrical stimulation position and a position to detect muscle sound are fixed, and the amplitude and frequency of an evoked mechanomyogram MMG can be quantitatively detected without depending on the electrical stimulation position and the muscle sound detection position.

Abstract: A knee examination method includes situating a patient on a patient support adjacent a robotic knee testing apparatus, the apparatus having a motion tracking system. The robotic knee testing apparatus is set up including defining a world coordinate system based on a fixed location of a transmitter of the motion tracking system. The patient is set up including determining one or more local coordinate systems each based on setting up the patient and on one or more robot based points. The robotic knee testing apparatus is operable to manipulate a leg of the patient.

Abstract: Disclosed herein are methods and apparatus for diagnosing a disease in the gingival region of an individual, comprising: quantitatively measuring blood flow or changes in blood flow in the gingival region of the individual, potentially comparing these data to that of a healthy subject, and diagnosing the disease based one of more of these quantities.

Abstract: The invention discloses a radio wave transducer for the detection of spinal segmental dysfunction, comprising two radio wave emitters and at least one switch; the two radio wave emitters are electrically connected to the switch; each of the two radio wave emitters has a RLC circuit consisting of a resistor, an inductor and a capacitor, one end of the resistor is electrically connected to one end of the inductance, the other end of the inductance is electrically connected to one end of the capacitor, the other end of the resistor is electrically connected to one end of the switch, the other end of the capacitor is electrically connected to the other end of the switch. This invention also discloses a method for detection of spinal segmental dysfunction.

Abstract: A knee examination method includes the steps of situating a patient on a patient support adjacent a robotic knee testing apparatus, setting up the robotic knee testing apparatus, further setting up the leg of the patient relative to the robotic knee testing apparatus, and, after the steps of setting up and further setting up, examining knee laxity of a knee of the patient. The step of examining includes operating the robotic knee testing apparatus to manipulate the tibia positioning assembly.

Abstract: Methods, techniques, apparatuses, and systems for setting up and tracking sleep consistency goals of users are provided. In one example, a computing system for setting a sleep schedule of a user of a biometric monitoring device may obtain sleep data derived from sensor data generated by the biometric monitoring device, store the sleep data in a sleep log data store as one or more sleep logs associated with an account assigned to the user, and calculate a target bedtime based on a scheduled waketime of the user and a sleep efficiency derived, at least in part, from the sleep data for one or more users stored in the sleep log data store. The computing system may also be configured to provide a number of personalized user interfaces to an individual for the purposes of setting a sleep schedule. Such interfaces may include parameters that are tailored to the individual sleep needs and/or characteristics of the individual's sleep.

Abstract: This invention mainly discloses an EOG-based sleep staging method which is used to improve of an accuracy of automatic sleep judging result. The method may be executed by a processor and comprises steps of reading a to-be-test data having a variation depending on time of EOG generated by a user during a sleep process; acquiring a plurality of eye movement characteristics based on a variation of the EOG of a period, with the characteristics including an eye movement ratio, a blink count, a low frequency power ratio, a high frequency power ratio, an alpha rhythm ratio, a spindle rhythm ratio, a delta rhythm ratio and an average amplitude of eletrooculogram (EOG) signals; and determining a sleep state of the period is a “WAKE stage”, a “REM stage”, a “S1 stage”, a “S2 stage”, or a “SWS stage” based on the EOG characteristics. Furthermore, a computer readable medium with stored programs, and electronic apparatuses are provided.

Abstract: A device and method for sleep monitoring, in particular to a device and method for determining time-to-sleep and wake periods during sleep and to a device and method for determining rapid eye movement (REM) sleep and non REM (NREM) sleep. The method for determining time-obtaining motion data representative of motion of a user to-sleep and wake periods during sleep comprising the steps of obtaining motion data representative of motion of a user; detecting the time-to-sleep from the motion data based on a first time-above-threshold (TAT) threshold and a first proportional detecting the time-to-sleep from the motion data based integration method (PIM) threshold; and detecting on a first time-above-threshold (TAT) threshold and a the wake periods during sleep from the motion data first proportional integration method (PIM) threshold based on a second TAT threshold and a second PIM threshold.

Abstract: Methods, techniques, apparatuses, and systems for setting up and tracking sleep consistency goals of users are provided. In one example, a computing system for setting a sleep schedule of a user of a biometric monitoring device may obtain sleep data derived from sensor data generated by the biometric monitoring device, store the sleep data in a sleep log data store as one or more sleep logs associated with an account assigned to the user, and calculate a target bedtime based on a scheduled waketime of the user and a sleep efficiency derived, at least in part, from the sleep data for one or more users stored in the sleep log data store. The computing system may also be configured to provide a number of personalized user interfaces to an individual for the purposes of setting a sleep schedule. Such interfaces may include parameters that are tailored to the individual sleep needs and/or characteristics of the individual's sleep.

Abstract: A new approach is proposed that contemplates system and method to support breath monitoring of a person via a plurality of breathing sensors embedded in a mattress the person is resting on. Once activated, each of the breathing sensors is configured to detect breathing activities or body movements caused by the breathing activities of a person lying on the mattress and report the breathing activities detected as electronic signals to a breathing monitor. Upon accepting the signals from the breathing sensors embedded in the mattress, the breathing monitor is configured to identify a breathing pattern based on the breathing activities of the person and detect any abnormal change in the breathing pattern of the person. If such abnormal change is detected, the breathing monitor is configured to generate and provide an alert to a monitoring party/caregiver of the person and/or produce an alarm to wake up the person in sleep.

Abstract: Systems and methods of identifying medical disorders in one or more subjects are disclosed herein. In one embodiment, sound is transmitted toward a subject and at least a portion of the sound reflected by the subject and is acquired as echo data. The acquired echo data is used to generate a motion waveform having a plurality of peaks detected therein. At feast a portion of the plurality of peaks may be indicative of movement of the subject. One or more medical disorders in the subject can be identified based on, for example, time durations and/or amplitude changes between peaks detected in the motion waveform.

Abstract: Apparatus is provided that includes a drug capsule containing an oral drug, and a sensing apparatus that includes a housing and a sensor. The housing is shaped so as to define exactly one hemispherical portion and exactly one cylindrical portion, which together define an internal surface tightly fitted to at least a portion of an external surface of the drug capsule. The sensor includes first and second electrodes, which comprise first and second electrode surfaces, respectively; and circuitry, which (a) is attached to the housing, (b) is electrically coupled to the first and the second electrode surfaces, and (c) is configured to drive a current between the first and the second electrode surfaces. Other embodiments are also described.

Abstract: A system for providing a connected dental device is disclosed. In particular, the system may include integrating a network chip or transceiver into a dental device, such as a toothbrush, so as to enable the dental device to communicate with a user device and one or more accessory devices. Once the user device and one or more accessory devices are paired with the user device, the system may track information associated with the dental device and the user using the dental device. Based on the tracked information, the system may determine an action to be performed by the user using the dental device. Using the dental device, the system may transmit a notification to the user device to alert the user of the action that needs to be performed. The system may also transmit notifications providing status information for the dental device and the one or more accessory devices.

Abstract: Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.

Abstract: One embodiment includes a method for monitoring nerve tissue which includes inserting a dilator into muscle, the dilator including first and second electrodes at the distal tip. While the dilator is in muscle, a system may communicate (a) a first series of unequal current amplitude applications (e.g., a series including 0.5, 7, 3, 5 mA applications) to the first electrode to produce at least a first evoked potential (e.g., a MAP or NAP), and (b) a second series of unequal current amplitude applications to the second electrode to produce at least a second evoked potential. The method further includes sensing the first and second evoked potentials and determining a relative location of a nerve based on the sensing of at least one of the first and second evoked potentials.

Abstract: An apparatus that monitors information associated with an oral cavity is provided, the apparatus comprising: a three-dimensional oral appliance; a data collection device having at least one sensor and/or hydrogel like material configured to sense the information associated with the oral cavity; an interface device cooperatively coupled to the data collection device, the interface device configured to transfer the information from the sensor device to a receiving device external to the oral cavity or the entire device is analyzed.

Abstract: An apparatus comprises a sensor for measuring a physiological parameter of a subject, wherein the physiological parameter sensor is adapted to be worn by the subject; an actuator comprising an electro-active polymer material, EAP, portion for adjusting the position of the physiological parameter sensor relative to the subject; a feedback sensor for measuring movement of the physiological parameter sensor and/or the subject; a controller configured to process the measurements of the feedback sensor and to adjust the position of the actuator based on information from the feedback sensor.

Abstract: An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

Abstract: A spine of an electrode assembly is constructed by simultaneously deploying a plurality of individual bobbins of lead wire radially around the longitudinal axis of a polymeric tube. A free end of lead wire from each bobbin is electrically connected to a respective electrode and the electrodes are sequentially installed from a distal first location on the polymeric tube to a proximal location. Each lead wire may be helically wound around the polymeric tube between the electrode to which the lead wire is electrically connected and a proximally adjacent electrode, such that each lead wire between adjacent pairs of electrodes has an alternating direction of winding.

Abstract: A mobile newborn care bed is configured to be positioned at a delivery location of an infant includes a bassinet containing a mattress for receiving the infant and a frame that supports the bassinet. At least two capacitive sensors are incorporated in the mattress that record cardiac signals, and an on-bed computing system is configured to receive the cardiac signals and determine a heart rate for the infant. A battery supported by the frame powers the on-bed computing system, and a digital display is communicatively connected to the on-bed computing system and displays the heart rate.

Abstract: An occupant support includes a vehicle seat, a sensor coupled to the vehicle seat, and a controller coupled to the sensor. The sensor provides a signal to the controller and the controller processes and responds to the sensed signal.

Abstract: A method includes obtaining load-deformation data for a joint, the load-deformation data being gathered via joint testing implemented by robotic test equipment, the robotic test equipment being configured for movement of the joint and comprising sensors to gather the load-deformation data during the movement. A load-deformation curve function for the load-deformation data is generated, the load-deformation curve function defining a curve fitted to the load-deformation data. A feature of the curve defined by the load-deformation curve function is quantified. A biomechanical characteristic of the joint is identified based on the quantified feature of the curve defined by the load-deformation curve function.

Abstract: A method comprises obtaining rotational data and translational data for a joint. The rotational and translational data is indicative of rotational and translational movement of the joint during rotational and translational joint testing, respectively. The rotational and translational joint testing is implemented by a robotic testing apparatus. Respective zero torque points are determined for the rotational and translational movement based on the rotational data and the translational data. The respective zero torque points are combined for the rotational and translational movement to determine an equilibrium position for the joint. A biomechanical characteristic of the joint is ascertained based on an analysis of the equilibrium position.

Abstract: A cluster database includes existing ECG datasets organized into clusters, wherein each existing ECG dataset includes an existing ECG waveform with at least one corresponding existing feature and existing interpretation. Each cluster is comprised of existing ECG datasets having a common existing feature. The cluster training module is executable by the processor to receive a new ECG waveform and a feature extracted from the new ECG waveform. The cluster training module then selects a cluster interpretation module based on the feature, wherein the cluster interpretation module is trained on one of the clusters from the cluster database. The cluster training module processes the new ECG waveform and/or the feature to provide a cluster interpretation output. The cluster interpretation output is then displayed on the user interface, and the cluster training module receives clinician input via the user interface accepting or rejecting the cluster interpretation output.

Abstract: A method for monitoring workplace safety and evaluating risks during lifting activities is provided, the method comprising receiving signals from wearable first and second devices, identifying portions of the signals corresponding to lifting activities, excerpting the portions of the signals corresponding to lifting activities, and calculating risk metrics based on measurements extracted from the excerpted portions of the signals, the risk metric indicative of high risk lifting activities.

Abstract: Provided is a system for supporting the treatment of vascular diseases by performing a blood flow simulation based on a medical image, the system comprising: an input unit that reads the medical image, fluid properties and boundary conditions from a data storage unit; a blood flow analysis execution unit that obtains a pressure field and a flow velocity field based on the medical image read by the input unit; a blood flow information calculation unit that calculates, based on the pressure field and the flow velocity field, blood flow information about a specific blood vessel being treated; a vascular treatment risk assessment unit that calculates, based on the calculated blood flow information, the proportion of a blood flow volume flowing into an aneurysm as a risk factor associated with the vascular treatment of the blood vessel being treated; and display units that display the calculation results to a user.