Patents Issued in December 28, 2017
  • Publication number: 20170369798
    Abstract: An olefin or a slack wax of 10 to 100 carbon atoms is oxidized by mixing said wax with a salt of an alkaline earth metal in an amount to provide 0.001 to 0.03 weight percent of the alkaline earth metal, the anion of the salt comprising 4 to 36 carbon atoms; heating the mixture to 100 to 180° C.; and supplying to the heated mixture a molecular oxygen-containing gas. The oxidation is conducted in the substantial absence of manganese or cobalt compounds. The oxidized wax may be esterified by reaction with an alcohol. The oxidized wax may be used in a coating composition.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 28, 2017
    Inventors: Jennifer E. Clark, Ben Faber, Gregory E. Moran, Britt A. Minch, David Boothe, Daniel J. Hunt, Miranda H. Koenig
  • Publication number: 20170369799
    Abstract: A process to prepare paraffins and waxes is provided, the process comprising: subjecting a Fischer-Tropsch product stream comprising paraffins having from 10 to 300 carbon atoms to a hydrogenation step, thereby obtaining a hydrogenated Fischer-Tropsch product stream comprising 10 to 300 carbon atoms; separating the hydrogenated Fischer-Tropsch product stream, thereby obtaining at least a fraction comprising 10 to 17 carbon atoms and a fraction comprising 18 to 300 carbon atoms; separating the fraction comprising 18 to 300 carbon atoms, thereby obtaining one or more first light waxes having a congealing point in the range of 30 to 75° C. and a second heavy wax having a congealing point in the range of 75 to 120° C.; and hydrofinishing one or more wax fractions having a congealing point in the range of 30 to 75° C. thereby obtaining one or more hydrofinished wax fractions having a congealing point in the range of 30 to 75° C.
    Type: Application
    Filed: December 29, 2015
    Publication date: December 28, 2017
    Inventors: Arend HOEK, Antonius Adrianus Maria ROOVERS, Kaushik MAJUMDER, Hélène TOLEDANO
  • Publication number: 20170369800
    Abstract: A method of optimizing system parameters in a crude unit to reduce corrosion and corrosion byproduct deposition in the crude unit is disclosed and claimed. The method includes measuring or predicting properties associated with the system parameters and using an automated controller to analyze the properties to cause adjustments in the chemical program to optimize the system parameters. Adjusting the system parameters effectively controls corrosion in the crude unit by reducing the corrosiveness of a fluid in the process stream and/or by protecting the system from a potentially corrosive substance. System parameter sensing probes are arranged at one or more locations in the process stream to allow accurate monitoring of the system parameters in the crude unit.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 28, 2017
    Applicant: ECOLAB USA INC.
    Inventors: Glenn L. Scattergood, Sam Ferguson
  • Publication number: 20170369801
    Abstract: An apparatus and a method for gasifying carbon-containing materials in which the material for gasification and oxygen, usually in the form of air, are supplied to a gas generator where the gasification takes place in a fixed bed reactor. The product gas is drawn off via a product gas line and introduced into a hot gas filter. A filter, preferably provided with filter candles, removes solids such as particles not yet gasified, ash and foreign bodies, while clean gas passes through and is taken off via a clean gas line. An outlet is provided in the bottom region of the hot gas filter to remove residual solids. The hot gas filter is supplied through a line with oxygen, preferably in the form of air, in its middle height region, between the filter bottom and the outlet.
    Type: Application
    Filed: July 7, 2016
    Publication date: December 28, 2017
    Inventor: Gaston GLOCK
  • Publication number: 20170369802
    Abstract: The present invention relates generally to the generation of bio-products from organic matter feedstocks. More specifically, the present invention relates to the use of pulping liquors in the hydrothermal/thermochemical conversion of lignocellulosic and/or fossilised organic feedstocks into biofuels (e.g. bio-oils) and/or chemical products (e.g. platform chemicals).
    Type: Application
    Filed: April 13, 2017
    Publication date: December 28, 2017
    Inventors: William Rowlands, Leonard James Humphreys, Robert Downie, Paul Watson
  • Publication number: 20170369803
    Abstract: There is described a biodiesel composition and process for producing biodiesel and related products. There is also described related fuels and fuel blends comprising biodiesel. The biodiesel composition may be prepared from a mixture comprising fats, oils and greases from sewer waste.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 28, 2017
    Applicants: Argent Energy (UK) Limited, Argent Energy Limited
    Inventor: Michael Scott
  • Publication number: 20170369804
    Abstract: Systems, processes, and catalysts are disclosed for obtaining fuels and fuel blends containing selected ratios of open-chain and closed-chain fuel-range hydrocarbons suitable for production of alternate fuels including gasolines, jet fuels, and diesel fuels. Fuel-range hydrocarbons may be derived from ethylene-containing feedstocks and ethanol-containing feedstocks.
    Type: Application
    Filed: August 18, 2017
    Publication date: December 28, 2017
    Applicant: Battelle Memorial Institute
    Inventors: Michael A. Lilga, Richard T. Hallen, Karl O. Albrecht, Alan R. Cooper, John G. Frye, Karthikeyan Kallupalayam Ramasamy
  • Publication number: 20170369805
    Abstract: Processes for producing high biogenic concentration Fischer-Tropsch liquids derived from the organic fraction of municipal solid wastes (MSW) feedstock that contains a relatively high concentration of biogenic carbon (derived from plants) and a relatively low concentration of non-biogenic carbon (derived from fossil sources) wherein the biogenic content of the Fischer-Tropsch liquids is the same as the biogenic content of the feedstock.
    Type: Application
    Filed: August 21, 2017
    Publication date: December 28, 2017
    Inventors: Stephen H. Lucas, Peter G. Tiverios, Lewis L. Rich
  • Publication number: 20170369806
    Abstract: A liquid fuel derived from processed biomass having extremely low water content and suitable for use in diesel engines or as an additive to petroleum based fuels, or which can be used as a petroleum or coal slurry substitute in those uses where a lower cost fuel have reduced emission is desired, is described.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Applicant: Permanente Corporation
    Inventors: Marc Seidner, Leo Seidner, Hanya Seidner
  • Publication number: 20170369807
    Abstract: A lubricant including an ionic liquid including a conjugate base and a conjugate acid, wherein the conjugate acid is represented by General Formula (A) below, and wherein a pKa of an acid that is a source of the conjugate base in acetonitrile is 10 or less, where, in General Formula (A), R is a group including a straight-chain hydrocarbon group having 6 or greater carbon atoms, and R1 and R2 are each independently a hydrocarbon group.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 28, 2017
    Inventors: Hirofumi Kondo, Kouki Hatsuda, Nobuo Tano, Pankaj Baghel
  • Publication number: 20170369808
    Abstract: A lubricating oil composition for an internal combustion engine including: (A) a lubricant base oil having a kinematic viscosity at 100° C.
    Type: Application
    Filed: June 19, 2017
    Publication date: December 28, 2017
    Applicant: JXTG NIPPON OIL & ENERGY CORPORATION
    Inventor: Shintaro KUSUHARA
  • Publication number: 20170369809
    Abstract: The disclosed technology relates to an additive composition and lubricating grease composition containing a synergistic combination of ingredients for inhibiting rust, particularly rust on mechanical devices subject to contact with salt water.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 28, 2017
    Inventor: Scott Capitosti
  • Publication number: 20170369810
    Abstract: The present invention relates to a lubricating composition containing: an oil of lubricating viscosity, a non-borated dispersant, a detergent, and an antiwear package comprising (a) a derivative of a hydroxycarboxylic acid, (b) an amine salt of a phosphoric acid ester, and (c) a phosphite having at least one hydrocarbyl group with 4 or more carbon atoms. The invention further provides for a method of lubricating a driveline device application by employing a lubricating composition containing the antiwear package.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Inventor: William R.S. Barton
  • Publication number: 20170369811
    Abstract: Provided is a lubricating oil composition to be used in an internal combustion engine having a sliding mechanism including a piston ring and a liner, the lubricating oil composition including: a base oil; (A) a poly(meth)acrylate; and (B) an organic molybdenum compound, in which: (A) the poly(meth)acrylate contains a polymer (A1) including a repeating unit derived from a (meth)acrylate represented by the following formula (1) and having a mass-average molecular weight of from 1,000 to 500,000; and a content of (B) the organic molybdenum compound in a total amount of the composition is from 0.01 mass % to 0.2 mass % in terms of a molybdenum atom: wherein R1 represents a hydrogen atom or a methyl group, and X represents a hydrogen atom, a hydrocarbon group having 1 to 60 carbon atoms, or a functional group-containing hydrocarbon group having 1 to 60 carbon atoms.
    Type: Application
    Filed: January 15, 2016
    Publication date: December 28, 2017
    Applicant: IDEMITSU KOSAN CO., LTD.
    Inventor: Moritsugu KASAI
  • Publication number: 20170369812
    Abstract: A method for inhibiting adsorption of ?-olefin in a lubricant composition to a metal surface is disclosed. The lubricant composition comprises any of oils of Group III, Group IV and polyisobutylenes classified into Group V according to the API base oil classification or a mixture thereof as a base oil, and the ?-olefin coexisting in an amount of 1% by mass or less based on the total amount of the composition. The method comprises adding a sarcosinic acid derivative, an aspartic acid derivative or a diethanolamine derivative, or a mixture thereof to the lubricant composition.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 28, 2017
    Applicant: SHELL OIL COMPANY
    Inventors: Hiroyuki TAZAKI, Mitsuhiro NAGAKARI, Hiroshi KANEKO
  • Publication number: 20170369813
    Abstract: A dielectric nanolubricant composition is provided. The dielectric nanolubricant composition includes a nano-engineered lubricant additive dispersed in a base. The nano-engineered lubricant additive may include a plurality of solid lubricant nanostructures having an open-ended architecture and an organic, inorganic, and/or polymeric medium intercalated in the nanostructures and/or encapsulate nanostructures. The base may include a grease or oil such as silicone grease or oil, lithium complex grease, lithium grease, calcium sulfonate grease, silica thickened perfluoropolyether (PFPE) grease or PFPE oil, for example. This dielectric nanolubricant composition provides better corrosion and water resistance, high dielectric strength, longer material life, more inert chemistries, better surface protection and asperity penetration, no curing, no staining, and environmentally friendly, compared to current products in the market.
    Type: Application
    Filed: August 11, 2017
    Publication date: December 28, 2017
    Applicant: The Board of Trustees of the University of Arkansas
    Inventors: Ajay P. Malshe, Wengyang Zhang
  • Publication number: 20170369814
    Abstract: Disclosed is a lubricating composition including a base oil, a surfactant system and a phase-change material, especially water. The lubricating composition according to the invention is used to lubricate engines, especially for a vehicle. It has improved thermal performances compared to lubricating compositions of prior art. It also reduces clogging of the engine parts.
    Type: Application
    Filed: December 22, 2015
    Publication date: December 28, 2017
    Inventor: Nicolas OBRECHT
  • Publication number: 20170369815
    Abstract: A method of separating oil from a composition containing an oil and water emulsion, by adding a separation additive which is a mixture of a fatty ester of an alkoxylated polyol and a fatty ester of alkoxylated glycerol, and performing at least one oil separation step. The method is particularly suitable for separating corn oil from stillage produced in a corn ethanol mill.
    Type: Application
    Filed: January 8, 2016
    Publication date: December 28, 2017
    Applicant: Croda, Inc.
    Inventors: Min Ma Wang, Craig Michael Sungail, Xin Chen
  • Publication number: 20170369816
    Abstract: Laundry detergents and their use for cold-water cleaning are disclosed. The detergents comprise a lipase and a mid-chain headgroup surfactant or an alkylene-bridged surfactant. The mid-chain headgroup surfactants have a C14-C30 alkyl chain and a polar group bonded to a central zone carbon of the C14-C30 alkyl chain. The alkylene-bridged surfactants comprise a C12-C18 alkyl chain, a polar group, and a C1-C2 alkylene group bonded to the polar group and a central zone carbon of the C12-C18 alkyl chain. Surprisingly, when combined with lipases, detergents formulated with the mid-chain headgroup or alkylene-bridged surfactants effectively liquefy greasy soils at low temperature and provide outstanding cold-water performance in removing greasy stains such as bacon grease, butter, cooked beef fat, or beef tallow from soiled articles.
    Type: Application
    Filed: December 29, 2015
    Publication date: December 28, 2017
    Inventors: Brian Holland, Randal Bernhardt, Branko Sajic
  • Publication number: 20170369817
    Abstract: The need for a liquid hard surface cleaning composition which provides improved grease removal and low suds is met using a combination of alkyl ethoxylated nonionic surfactant; an anionic surfactant selected from the group consisting of: an alkyl sulphate, a sulphonic acid or sulphonate surfactant, and mixtures thereof; and a co-surfactant in specific ratios.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 28, 2017
    Inventor: Geert Andre DELEERSNYDER
  • Publication number: 20170369818
    Abstract: A liquid laundry detergent composition capable of suspending particles and insoluble materials while remaining readily pourable. The composition is stable over long periods of time. In one aspect, the liquid laundry detergent comprises in an aqueous medium: a) at least one nonethoxylated anionic surfactant; b) at least one ethoxylated anionic surfactant; c) at least one nonionic fatty alcohol ethoxylate surfactant; d) an optional surfactant selected from a nonionic surfactant other than c), a cationic surfactant, fatty acid salt surfactant, an ampholytic surfactant, and mixtures thereof; and e) a nonionic, amphiphilic, emulsion polymer that is crosslinked with an amphiphilic crosslinking agent.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 28, 2017
    Inventors: Jung Hyun Park, Francine I. Shuster, Sinan Li
  • Publication number: 20170369819
    Abstract: Aminocarboxylate builders having 1 to 3 amino groups and 2 to 6 carboxylic acid groups improve blood soil removal, particularly from fabrics. Improved removal of body soils from fabrics is achieved by washing the fabric in a first wash liquor comprising one or more carboxylate builders, followed by a second wash in a wash liquor comprising surfactant.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 28, 2017
    Inventors: Francesco DE BUZZACCARINI, Xinbei SONG, William Mario Laurent VERSTRAETEN
  • Publication number: 20170369820
    Abstract: A cleaning composition comprising: a. At least one alkanolamine b. At least one mineral acid c. At least one salt of a hydroxycarboxylic acid d. At least one protease enzyme; wherein said composition contains no surfactant.
    Type: Application
    Filed: January 21, 2016
    Publication date: December 28, 2017
    Applicant: Whiteley Corporation Pty. Ltd.
    Inventors: Trevor Owen Glasbey, Nicolas Alan Roberts, Christopher David Hoffman, Phillip John Morgan
  • Publication number: 20170369821
    Abstract: The present disclosure relates to a cleaning composition for removing an oxide including one selected from an organic acid, an inorganic acid, and any combination thereof; one selected from an organic salt, an inorganic salt, and any combination thereof; an oxidizing agent; a surfactant; and water, and a method of cleaning using the cleaning composition.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 28, 2017
    Inventors: Sungsoon Im, Kyuhwan Hwang, Youngmin Moon, Minho Moon, Inho Kong, Changsub Kim, Hotae Kim, Jaehwan Jin, Donguk Hwang
  • Publication number: 20170369822
    Abstract: The present disclosure relates to water-soluble unit dose articles made from a combination of chemically different water-soluble films and optionally containing compositions that are at least partially enclosed by the water-soluble films in at least one compartment.
    Type: Application
    Filed: June 12, 2017
    Publication date: December 28, 2017
    Inventors: Philip Frank Souter, Robby Renilde Francois Keuleers, Regine Labeque, Florence Catherine Courchay, Marc Rene Bert Renmans, David M. Lee, Steven G. Friedrich, Lee K. Yeung, Shinsuke Nii
  • Publication number: 20170369823
    Abstract: The present disclosure relates to pouches made from a combination of chemically different water-soluble films and optionally containing a composition (e.g. a household care composition or non-household care composition) that is at least partially enclosed by the water-soluble films in at least one compartment.
    Type: Application
    Filed: June 12, 2017
    Publication date: December 28, 2017
    Inventors: Philip Frank Souter, Robby Renilde Francois Keuleers, Regine Labeque, Florence Catherine Courchay, Marc Rene Bert Renmans, David M. Lee, Steven G. Friedrich, Lee K. Yeung, Shinsuke Nii
  • Publication number: 20170369824
    Abstract: A portioned washing or cleaning agent in a container made of water-soluble material comprising at least two compartments which are separated from each other, wherein in at least one compartment a liquid washing or cleaning agent and in at least one further compartment, different herefrom, a powdery washing or cleaning agent is located which comprises core shell microcapsules in the form of microcapsule granulate, wherein the microcapsules comprise at least one additive in the core.
    Type: Application
    Filed: September 6, 2017
    Publication date: December 28, 2017
    Applicant: Henkel AG & Co. KGaA
    Inventors: Matthias Sunder, Frank Meier, Mario Sturm
  • Publication number: 20170369825
    Abstract: A container assembly (10) for aging a liquid (14) includes: a container (12) that retains the liquid (14) being aged, the container (12) including a container aperture (24); and an oxygenator (16) that is positioned adjacent to the container aperture (24), the oxygenator (16) including a porous oxygenator membrane (38B) that allows for the flow of air into the container (12) through the oxygenator membrane (38B) and the container aperture (24).
    Type: Application
    Filed: December 23, 2015
    Publication date: December 28, 2017
    Inventor: Jonathan William Roleder
  • Publication number: 20170369826
    Abstract: A lab-on-chip type system, capable of identifying antibiotic sensitivity at the point of care of patients, especially in rural areas, clinics, hospitals that do not have care 24/7, hospitals with low level of equipment, among others, from the extraction of a sample, comprising a micro device or medical base device and a dispenser, wherein said micro device comprises a plurality of microwells, arranged in a circular fashion on one of the faces of the micro device, and wherein the micro-dispenser comprises a central plunger for taking and supplying the sample, a chamber for storage and distribution of the sample and a plurality of microdispensers arranged in a circular manner through which the sample is introduced into the microwells of the micro device.
    Type: Application
    Filed: January 6, 2015
    Publication date: December 28, 2017
    Inventors: Sara DROGUETT BIZET, Mario SOTO AGUILERA
  • Publication number: 20170369827
    Abstract: A system and method for printing cells in a medium. A multi-dimensional printer, stably constructed of low-mass parts, can include a computer numerically controlled system that can enable motors driving delivery systems. The motors can include encoders that can enable achieving arbitrary resolution. The motors can drive ballscrews to enable linear motion of delivery systems, and the delivery systems can enable printing of a biological material in a pre-selected pattern in a petri dish. The petri dish can accommodate a medium such as a gel, and can further accommodate a vision system that can detect actual position and deflection of the delivery system needle. The printer can accommodate multiple delivery systems and therefore multiple needles of various sizes.
    Type: Application
    Filed: July 12, 2017
    Publication date: December 28, 2017
    Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Jonathan Parker, John C. Anastasiou, Michael C. Tilley
  • Publication number: 20170369828
    Abstract: A variable diameter bioreactor vessel is provided that includes a first vessel section having a first diameter configured to hold a liquid media and biologic material, and a second vessel section having a second diameter that is greater than the first diameter such that the liquid media can be increased from a first volume to a second volume within the vessel.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 28, 2017
    Inventors: Michael MIETZNER, Rajesh BERI, Edward GUNDERSON
  • Publication number: 20170369829
    Abstract: Provided herein are methods for culturing patient-derived tumor cell spheroids in a three-dimensional microfluidic device. The method comprises mincing primary tumor sample in a medium supplemented with serum; treating the minced primary tumor sample with a composition comprising an enzyme; collecting tumor spheroids having a diameter of 10 ?m to 500 ?m from the enzyme treated sample; suspending the tumor spheroids in biocompatible gel; and culturing the tumor spheroids in a three dimensional microfluidic device. Methods for identifying an agent for treating cancer and microfluidic devices that allow for the simultaneous exposure of the cultured patient-derived primary tumor cell spheroids to a treatment of choice and to control treatment are also provided.
    Type: Application
    Filed: January 7, 2016
    Publication date: December 28, 2017
    Applicant: Dana-Farber Cancer Institute, Inc.
    Inventors: David Barbie, Amir Aref, Thanh Barbie, Russell W. Jenkins, Kwok-kin Wong
  • Publication number: 20170369830
    Abstract: A cell culture method is a cell culture method for arranging cultured cells in a culture dish and continuously culturing the cultured cells by supplying a liquid required to grow or maintain the cultured cells to the culture dish and discharging the liquid from the culture dish. The cell culture method includes: providing a supply port of the liquid at one end of the culture dish and providing a discharge port of the liquid at other end of the culture dish so as to sandwich the cultured cells between the supply port and the discharge port, and discharging the liquid while supplying the liquid to the culture dish so that a moving linear velocity of the liquid from the supply port toward the discharge port is less than a maximum velocity at which shear stress is not applied to the cultured cells.
    Type: Application
    Filed: December 10, 2015
    Publication date: December 28, 2017
    Inventors: Jun SUZUKI, Tadataka KAMIYAMA, Atsuhito OKONOGI, Toru MATSUME
  • Publication number: 20170369831
    Abstract: A system and process for enhancing sensory attributes of a beverage product are described. According to one embodiment, the process comprises providing a consumable beverage. A sonication process is applied to the consumable beverage utilizing a sonication unit. Chemical reactions in the consumable beverage are catalyzed to modify a sensory attribute of the consumable beverage.
    Type: Application
    Filed: June 23, 2017
    Publication date: December 28, 2017
    Applicant: E.& J. Gallo Winery
    Inventors: Ajwinder Dhesi, Rachel Dokich, Sameen Kiayei, Raley Lee, Dharma Bangalore, Dhruba Das, David Warter, Ravi Ponangi, Richard Ntuli
  • Publication number: 20170369832
    Abstract: A heating assembly for a bioreactor is disclosed. The heating assembly includes a holder having a plurality of segments coupled to each other to define a unitary structure and a heating component coupled to at least one segment of the plurality of segments. The unitary structure includes a top end, a bottom end, and a side wall. The side wall extends between the top end and the bottom end and along a circumferential direction of the heating assembly to define a cavity. At least a portion of the unitary structure has a gradually varied perimeter along a direction perpendicular to a plane which intersects the side wall and is parallel to the top end and the bottom end.
    Type: Application
    Filed: June 27, 2016
    Publication date: December 28, 2017
    Inventors: Ying Mao, Weston Blaine Griffin, Younkoo Jeong
  • Publication number: 20170369833
    Abstract: A bottle includes a body, a cap mounted to a cap neck of the body. The cap has an outer peripheral portion which is provided with a protrusion. Around the cap, there is provided a position indicator indicating whether the cap is at a correctly closed position, based on the positional relationship between the protrusion and the position indicator.
    Type: Application
    Filed: June 27, 2017
    Publication date: December 28, 2017
    Applicants: DENSO WAVE INCORPORATED, ANIMAL STEM CELL
    Inventors: Koji KAMIYA, Wataru SAITO, Kazuhiro NAGAIKE
  • Publication number: 20170369834
    Abstract: The invention pertains to compositions for preserving biological material or active molecules, particularly microorganisms, and their uses.
    Type: Application
    Filed: February 6, 2017
    Publication date: December 28, 2017
    Inventors: CHRISTOPHE HOLLARD, David FETT, Lars PETERSEN
  • Publication number: 20170369835
    Abstract: The present invention relates to a method for degrading DNA in a sample obtained by microbial fermentation or bio-transformation, comprising treating the sample with a combination of increased temperature and low pH. It also relates to a method for releasing DNA from a microbial cell, comprising incubating the microbial cell at a temperature of 45° C. to 55° C. for two to ten hours. Finally, the present invention provides a method for producing a product, comprising a step of releasing DNA from a microbial cell and degrading said DNA.
    Type: Application
    Filed: December 9, 2015
    Publication date: December 28, 2017
    Inventors: Birgit HOFF, Stefan HAEFNER, Weol Kyu JEONG, Edzard SCHOLTEN
  • Publication number: 20170369836
    Abstract: The present invention discloses a serum-free medium for full suspension culture of MDCK cells and a preparation method of the serum-free medium. The serum-free medium for full suspension culture of the MDCK cells comprises basic metabolic nutrients, nucleotide, vitamins, inorganic salts, a shear force protective agent, a cell clustering resisting agent, a pH buffer agent, a pH indicator, an influenza virus proliferation accelerant and other additives. The preparation method of the serum-free medium for the full suspension culture of the MDCK cells comprises the following steps: 1) preparing a mixed solution: dissolving and mixing raw materials; and 2) regulating pH: regulating the pH of the mixed solution to 6.3 to 6.7, and setting a constant volume to obtain the serum-free medium for the full suspension culture of the MDCK cells.
    Type: Application
    Filed: June 11, 2017
    Publication date: December 28, 2017
    Inventors: RUIAI CHEN, Hanzhang Lai, Wensong Tan, Xuanzi Zhan, Xuping Liu, Kangcong MAI, Weilan Pan, Xiaofen Wang, Huajian Chen, Peijun Chen, Jiahua Xu, Qin Tang, Wenyan Zhang, Yan Gao
  • Publication number: 20170369837
    Abstract: The invention provides stable feed media containing pyruvate and methods for stabilizing feed media by adding pyruvate. The invention further provides methods for producing proteins using such media and proteins produced through the use of such methods.
    Type: Application
    Filed: August 8, 2017
    Publication date: December 28, 2017
    Applicant: AMGEN INC.
    Inventors: Arvia Eleanor MORRIS, Aurora Villegas VIAJE, Erika PINEDA
  • Publication number: 20170369838
    Abstract: The invention relates to a long term cell culturing method and a cell culturing apparatus and kit that employ a porous polyimide film. The invention further relates to a cell cryopreservation method and kit employing the porous polyimide film.
    Type: Application
    Filed: January 26, 2016
    Publication date: December 28, 2017
    Inventors: Masahiko HAGIHARA, Motohisa SHIMIZU, Yukinori WADA
  • Publication number: 20170369839
    Abstract: Provided herein are methods and compositions relating, in part, to the generation of human progenitor cells committed to the lung lineage and uses of such cells for treatment of lung diseases/disorders or injury to the lung. Whether an adult stem cell can be isolated from human adult lung remains controversial in the art and at present, methods for isolating and using adult lung stem cells from humans lack reproducibility. Thus, the methods and compositions described herein are advantageous over the present state of knowledge in the art and permit the generation of human lung progenitor cells for treatment, tissue engineering, and screening assays.
    Type: Application
    Filed: June 28, 2017
    Publication date: December 28, 2017
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Jayaraj Rajagopal, Hongmei Mou
  • Publication number: 20170369840
    Abstract: Methods, compositions and kits for producing functional neurons, astroctyes, oligodendrocytes and progenitor cells thereof are provided. These methods, compositions and kits find use in producing neurons, astrocytes, oligodendrocytes, and progenitor cells thereof for transplantation, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example for use in treating human disorders of the CNS. Also provided are methods, compositions and kits for screening candidate agents for activity in converting cells into neuronal cells, astrocytes, oligodendrocytes, and progenitor cells thereof.
    Type: Application
    Filed: July 17, 2017
    Publication date: December 28, 2017
    Inventors: Marius Wernig, Thomas C. Sudhof, Thomas Vierbuchen, Austin Ostermeier, Zhiping Pang
  • Publication number: 20170369841
    Abstract: Provided is a method for increasing the proportion of memory T cells in a T cell population, said method comprising a step of adding a modulator for the retinoid metabolic pathway and/or a modulator for the retinoic acid signaling system to the T cell population.
    Type: Application
    Filed: December 22, 2015
    Publication date: December 28, 2017
    Applicant: International Institute of Cancer Immunology, Inc.
    Inventors: Haruo SUGIYAMA, Fumihiro FUJIKI
  • Publication number: 20170369842
    Abstract: The invention provides methods of differentiating primate pluripotent stem cells into cells of hematopoietic lineage. The invention further provides hematopoietic lineage cells differentiated from primate pluripotent stem cells, as well as methods of using the same and kits comprising the same.
    Type: Application
    Filed: February 6, 2017
    Publication date: December 28, 2017
    Inventors: Suyi Tseng, Anish Sen Majumdar, Kevin Nishimoto, Anita Reddy, Jane S. Lebkowski
  • Publication number: 20170369843
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: March 29, 2017
    Publication date: December 28, 2017
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Publication number: 20170369844
    Abstract: Described are embodiments that include methods and devices for separating composite liquids into components. Embodiments involve the use of a flexible membrane for separating a composite liquid into components. The composite liquid may include, in embodiments, a cellular containing liquid, such as whole blood or components of whole blood. In one specific embodiment, the composite liquid is a buffy coat.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Applicant: Terumo BCT, Inc.
    Inventors: James R. LADTKOW, Geoffrey M. UHL, Jeremy P. KOLENBRANDER, Briden Ray STANTON
  • Publication number: 20170369845
    Abstract: Provided herein are methods for the isolation of platelets, for example, isolation of platelets from umbilical cord blood. In certain embodiments, presented herein are methods for preparation of platelet rich plasma. In one aspect, provided herein are methods for isolation of platelets from blood. In certain embodiments, presented herein are methods for isolation of platelets from cord blood, e.g., human cord blood. The isolated platelets can be used for a variety of applications, including, for example, methods of wound healing, organ repair and/or regeneration, and/or tissue repair and/or regeneration, in either autologous or allogenic settings.
    Type: Application
    Filed: December 30, 2015
    Publication date: December 28, 2017
    Applicant: ANTHROGENESIS CORPORATION
    Inventor: Manoochehr KHORSHIDI
  • Publication number: 20170369846
    Abstract: An object of the present invention is to provide a novel method for sorting cardiomyocytes. Another object of the present invention is to provide a method for producing high-purity cardiomyocytes and a kit used therefor. The present invention provides a method for sorting cardiomyocytes, comprising a step of introducing miRNA-responsive mRNA into a cell group, wherein the miRNA-responsive mRNA consists of a sequence comprising the following (i) and (ii): (i) a nucleic acid specifically recognized by miRNA specifically expressed in cardiomyocytes, and (ii) a nucleic acid corresponding to the coding region of a gene, wherein translation of (ii) the nucleic acid corresponding to the coding region of a gene into protein is regulated by the nucleic acid sequence in (i) above, thereby achieving the aforementioned objects.
    Type: Application
    Filed: March 20, 2015
    Publication date: December 28, 2017
    Inventors: Yoshinori Yoshida, Hirohide Saito, Kenji Miki, Kei Endo, Seiya Takahashi
  • Publication number: 20170369847
    Abstract: Provided herein are tissues containing semiconductor nanomaterials and methods of preparing and using the same.
    Type: Application
    Filed: January 15, 2016
    Publication date: December 28, 2017
    Inventors: Ying Mei, Tan Yu, Dylan Richards, Donald R. Menick, Bozhi Tian