Patents Issued in February 15, 2018
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Publication number: 20180043314Abstract: Disclosed are a copolymer, porous membranes made from the copolymer, and a method of treating fluids to remove metal ions using the porous membranes, for example, from fluids originating in the microelectronics industry, wherein the copolymer includes monomeric units I and II, wherein monomeric unit I is of the formula A-X—CH2—B, wherein A is Rf—(CH2)n, Rf is a perfluoro alkyl group of the formula CF3—(CF2)x—, wherein x is 3-12, n is 1-6, X is O or S, and B is vinylphenyl, and monomeric unit II is vinylpyridine.Type: ApplicationFiled: August 15, 2016Publication date: February 15, 2018Applicant: Pall CorporationInventors: Frank Okezie Onyemauwa, Hassan Ait-Haddou
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Publication number: 20180043315Abstract: A two-layer membrane including a polymer layer and a support layer, the polymer layer being disposed on a surface of the support layer. The polymer layer, having a pore size of at most 50 nm and a thickness of 5 nm to 10 ?m, is formed of an amphiphilic copolymer that contains both charged groups and hydrophobic groups. The support layer has a pore size of 3 nm to 10 ?m, which is larger than the pore size of the polymer layer. Also disclosed is a process of filtering a liquid using the two-layer membrane described above.Type: ApplicationFiled: March 8, 2016Publication date: February 15, 2018Inventors: Ayse Asatekin Alexiou, Ilin Sadeghi
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Publication number: 20180043316Abstract: Disclosed are methods and devices useful for aerating and or adding additives to carbon-containing aqueous waste.Type: ApplicationFiled: October 23, 2017Publication date: February 15, 2018Inventors: Yaakov Anker, Adi Nocham
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Publication number: 20180043317Abstract: A quick disconnect pump assembly is disclosed. The pump assembly includes a housing with inlet and outlet ports, an elongate slot, and a retainer channel. A sliding lock moves within the slot between a locked position and an unlocked position. The sliding lock includes inlet and outlet port openings and a sliding lock retainer opening. The inlet and outlet port openings each engage and retain a removable fitting when the sliding lock is in the locked position, but do not engage or retain the removable fitting when the sliding lock is in the unlocked position. The pump assembly also includes a sliding lock retainer which passes through the sliding lock retainer opening to prevent removal of the sliding lock from the elongate slot. A fluid pump and a beverage dispenser utilizing the pump assembly are also disclosed.Type: ApplicationFiled: August 10, 2016Publication date: February 15, 2018Applicant: Standex International CorporationInventors: Robert R. Kimberlin, Brian Waters
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Publication number: 20180043318Abstract: A liquid treatment apparatus (10) for processing a liquid includes an inlet nozzle (12) having an orifice (16) for directing a flow of liquid through the orifice (16) to define a fluid jet, and a concial diffuser (18) including a tip (20), a base portion (22), and a curved surface (26) therebetween. The conical diffuser (18) is generally aligned with the orifice (16) such that the fluid jet impacts upon the tip (20) of the conical diffuser (18). Moreover, the curvature of the curved surface (26) is selected to maintain a substantially constant Froude number of the liquid along the conical diffuser (18).Type: ApplicationFiled: February 26, 2016Publication date: February 15, 2018Inventor: Allison Sprague
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Publication number: 20180043319Abstract: A Venturi device for introducing a second fluid into a first fluid includes a T-joint, a converging component, and a diverging component. The T-joint component includes a first elongated tube extending along a first direction and a second elongated tube extending along a second direction being perpendicular to the first direction. The converging component is shaped and dimensioned to slip fit within a first through-opening of the first elongated tube through a first inlet port and has a cross-section that decreases along the first direction from the first inlet port to an inner section of the first though-opening. The diverging component is shaped and dimensioned to slip fit within the first through-opening of the first elongated tube through an outlet port and has a cross-section that increases along the first direction from the inner section of the first though-opening to the outlet port. The converging component is coaxially aligned with the diverging component along the first direction.Type: ApplicationFiled: August 11, 2017Publication date: February 15, 2018Inventors: EVAN SCHNEIDER, ALEXANDER MITCHELL
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Publication number: 20180043320Abstract: The present disclosure is directed towards improved systems and methods for large-scale production of nanoparticles used for delivery of therapeutic material. The apparatus can be used to manufacture a wide array of nanoparticles containing therapeutic material including, but not limited to, lipid nanoparticles and polymer nanoparticles. In certain embodiments, continuous flow operation and parallelization of microfluidic mixers contribute to increased nanoparticle production volume.Type: ApplicationFiled: February 24, 2016Publication date: February 15, 2018Applicant: The University of British ColumbiaInventors: Euan RAMSAY, Robert James TAYLOR, Timothy LEAVER, Andre WILD, Kevin OU, Colin WALSH
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Publication number: 20180043321Abstract: A stirring unit for stirring a fluid contained in a vessel includes a mixing body for stirring the fluid by rotating around a rotation axis, and a magnet or a magnetic substance for receiving a rotating magnetic field for rotating the mixing body, in which a suction port and a discharge port for the fluid are provided on a surface of the mixing body, a plurality of flow paths connecting the suction port and the discharge port are provided inside the mixture, the suction port is disposed at a position on the rotation axis or at a position closer to the rotation axis than the discharge port, and the discharge port is disposed at a position outside the rotation axis than the suction port.Type: ApplicationFiled: October 17, 2017Publication date: February 15, 2018Inventor: Noboru MOCHIZUKI
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Publication number: 20180043322Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.Type: ApplicationFiled: October 24, 2017Publication date: February 15, 2018Inventors: Martin Morrissey, Brian Pereira
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Publication number: 20180043323Abstract: An exemplary pharmaceutical compounding system and device for mixing materials from at least two distinct material sources can include a transfer set and junction structure that has a junction body, a first inlet port located at a first portion of the junction body, a second inlet port located at a second portion of the junction body, and an outlet port located at a third portion of the junction body. A mixing chamber can be located between the outlet port and both the first inlet port and second inlet port, the mixing chamber configured to mix fluid received from both the first inlet port and second inlet port and to deliver the fluid to the outlet port. An attachment structure can be located on the junction body and configured to attach the junction structure to the housing of the compounding device.Type: ApplicationFiled: October 28, 2017Publication date: February 15, 2018Inventors: Mike Janders, Mariano Mumpower, Benjamin R. Lane
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Publication number: 20180043324Abstract: Pulverulent alkali metal alkyl siliconates having lesser hydroscopicity and improved hydrophobicity in construction materials are produced by spray drying an aqueous solution of an alkali metal alkylsiliconate having a defined range of alkali metal content, a low alcohol content, and a low chlorine content.Type: ApplicationFiled: February 19, 2016Publication date: February 15, 2018Applicant: Wacker Chemie AGInventors: Michael STEPP, Daniel SCHILDBACH
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Publication number: 20180043325Abstract: Assemblies as disclosed herein for making superhard products by HPHT process comprise a first can portion for accommodating a mixture of materials therein and a second can mated with the first can portion. A leak-tight seal is provided between the first can portion and second can portion in a manner that accommodates the manufacture of relatively longer superhard products without having to change other elements or members used for HPHT processing to thereby provide improved manufacturing flexibility and cost efficiency.Type: ApplicationFiled: March 9, 2016Publication date: February 15, 2018Inventors: David P. DenBoer, Clint Hamilton, Michael David France, Ryan J. Davis, Lynn L. Belnap, Yi Fang
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Publication number: 20180043326Abstract: An apparatus is presented for the transferring of catalyst from an upstream vessel to a downstream vessel. The apparatus includes a non-mechanical valve and a transfer line, wherein a lift gas provides for carrying catalyst through the transfer line. The non-mechanical valve has a catalyst inlet and a lift gas inlet to provide for a consistent flow of catalyst and lift gas to the transfer line.Type: ApplicationFiled: October 30, 2017Publication date: February 15, 2018Inventors: Charles Brabson, Rajeswar Gattupalli, Richard Gaicki, Kyle P. Austin, Christopher Naunheimer, Michael J. Vetter
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Publication number: 20180043327Abstract: The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a portion of which react with each other within the liquid spray discharge to form a reaction product. The system also includes a collector positioned to receive the liquid spray discharge including the unreacted molecules and the reaction product. The system also includes a recirculation loop connected from the collector to the pneumatic sprayer in order to allow the unreacted molecules and the reaction product to be recycled through the pneumatic sprayer, thereby allowing a plurality of the unreacted molecules to react with each other as the unreacted molecules cycle again through the system.Type: ApplicationFiled: August 10, 2017Publication date: February 15, 2018Applicant: Purdue Research FoundationInventors: Robert Graham Cooks, Michael Stanley Wleklinski, David Logsdon
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Publication number: 20180043328Abstract: A mixed salt composition adapted for use as a sorbent for carbon dioxide removal from a gaseous stream is provided, the composition being in solid form and including magnesium oxide, an alkali metal carbonate, and an alkali metal nitrate, wherein the composition has a molar excess of magnesium characterized by a Mg:X atomic ratio of at least about 3:1, wherein X is the alkali metal. A process for preparing the mixed salt is also provided, the process including mixing a magnesium salt with a solution comprising alkali metal ions, carbonate ions, and nitrate ions to form a slurry or colloid including a solid mixed salt including magnesium carbonate; separating the solid mixed salt from the slurry or colloid to form a wet cake; drying the wet cake to form a dry cake including the solid mixed salt; and calcining the dry cake to form a mixed salt sorbent.Type: ApplicationFiled: October 19, 2017Publication date: February 15, 2018Inventors: Jian-Ping Shen, Luke James Ivor Coleman, Marty Alan Lail, Raghubir Prasad Gupta, Brian Scott Turk
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Publication number: 20180043329Abstract: A sorbent product, including from about 1 wt % to about 99 wt %, based on the total weight of the sorbent product, of at least one base sorbent material; and from about 1 wt % to about 99 wt %, based on the total weight of the sorbent product, of at least one binder. The sorbent product may further include at least from about 0 wt % to about 99% wt %, based on the total weight of the sorbent product, of at least one additional additive. Methods for making same and methods and systems for controlling multiple pollutants are also included.Type: ApplicationFiled: July 7, 2015Publication date: February 15, 2018Applicant: Carbonxt, Inc.Inventors: David W. Mazyck, Heather Byrne, Regina Rodriguez, Christine Valcarce
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Publication number: 20180043330Abstract: A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.Type: ApplicationFiled: February 22, 2016Publication date: February 15, 2018Inventors: Tomislav FRISCIC, Chao-Jun LI, Simon GIRARD, Cristina MOTTILLO, Christopher Walter NICKELS
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Publication number: 20180043331Abstract: Compositions that can be used to adsorb low concentration, of unwanted or target substances from a dynamic fluid stream or from an enclosed static vapor phase. Such adsorbency can be obtained with thermoplastic materials used in the form of bulk polymer or a film, fiber, web, woven fabric, non-woven fabric, sheet, packaging and other such structures including or surrounding the enclosed volume. The concentration should be reduced to non-offensive sensed limits or a limit that does not produce a biological response.Type: ApplicationFiled: October 17, 2017Publication date: February 15, 2018Inventor: Willard E. Wood
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Publication number: 20180043332Abstract: The present invention relates to superabsorbent polymer having an improved absorption speed through micropores formed inside, and a method for preparing the same.Type: ApplicationFiled: April 14, 2016Publication date: February 15, 2018Applicant: LG Chem, Ltd.Inventors: Kum Hyoung Lee, Gi Cheul Kim, Sung Soo Park, Ye Sol Yang
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Publication number: 20180043333Abstract: Provided are a technique for preparing a porous cellulose medium without using a special gelling agent for a solution in which cellulose acetate serving as a raw material is dissolved; and a porous cellulose medium and the like produced using the technique. A method for producing a porous cellulose medium comprises the step of preparing a flowable homogeneous composition comprising cellulose acetate, a basic compound, and a solvent including water, and gelling the composition by deacetylation reaction of the cellulose acetate.Type: ApplicationFiled: April 1, 2016Publication date: February 15, 2018Applicant: DAICEL CORPORATIONInventors: Toru SHIBATA, Yasuto MORISHITA, Keiji NISHIHARA
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Publication number: 20180043334Abstract: The present invention provides a methane oxidation catalyst comprising one or more noble metals supported on zirconia, wherein the zirconia comprises tetragonal zirconia and monoclinic zirconia, and wherein the weight ratio of tetragonal zirconia to monoclinic zirconia is in the range of from 1:1 to 31:1. The invention further provides a process for preparing a methane oxidation catalyst, a methane oxidation catalyst thus prepared and a method of oxidizing methane.Type: ApplicationFiled: March 3, 2016Publication date: February 15, 2018Inventors: Peter Tanev TANEV, Mario SOORHOLTZ
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Publication number: 20180043335Abstract: A lean burn engine exhaust treatment articles comprising a low temperature lean NOx trap (LT-LNT) composition and methods for their use is disclosed. A lean burn engine exhaust gas treatment system including the lean burn engine exhaust treatment articles is also disclosed. The low temperature lean NOx trap (LT-LNT) compositions can comprise a washcoat layer on a carrier substrate, the washcoat layer including a platinum group metal component impregnated on a first support material comprising at least 50% alumina. The washcoat layer may further include a low temperature NOx storage material comprising a bulk particulate reducible metal oxide. Methods of monitoring the aging state of a lean burn oxidation catalyst in a lean burn engine catalyst system are also disclosed.Type: ApplicationFiled: March 3, 2016Publication date: February 15, 2018Applicant: BASF CorporationInventors: Gerd GRUBERT, Torsten NEUBAUER, Alfred PUNKE, Marcus HILGENDORFF, Yuejin LI
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Publication number: 20180043336Abstract: A lean NOx trap composition for the treatment of exhaust gas emissions, such as the oxidation of unburned hydrocarbons (HC), and carbon monoxide (CO), and the trapping and reduction of nitrogen oxides (NOx) is disclosed. The lean NOx trap composition can have a washcoat layer on a carrier substrate including a first support material comprising greater than 50% by weight of a reducible metal oxide; 10 to 30% by weight of alkaline earth metal supported on a second support material comprising a refractory metal oxide and 50% or less by weight of a reducible metal oxide and; and a platinum group metal component supported on at least one of the first support material and/or the second support material. A portion of the first support material may further include 0.5% to 10% by weight of an alkaline earth metal.Type: ApplicationFiled: March 3, 2016Publication date: February 15, 2018Applicant: BASF CorporationInventors: Gerd GRUBERT, Torsten NEUBAUER, Alfred PUNKE, Marcus HILGENDORFF, Marko BUCHHOLZ, Matthew CAUDLE
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Publication number: 20180043337Abstract: A catalyst comprising gold and a porous support containing at least one refractory oxide, in which the gold content is in the range 0.01% to 5% by weight with respect to the total weight of catalyst, and in which the particles of gold are distributed homogeneously through said porous support and have a dimension, measured by transmission electron microscopy, in the range 0.5 to 5 nm.Type: ApplicationFiled: February 9, 2016Publication date: February 15, 2018Applicant: IFP Energies NouvellesInventors: Amandine CABIAC, Antoine HUGON
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Publication number: 20180043338Abstract: The present invention relates to a dehydrogenation process starting from reagents selected from single butenes, or mixtures thereof, or mixtures of butenes with butanes, to give 1-3 butadiene using catalytic composition of microspheroidal alumina and an active component containing a mixture comprising Gallium and/or Gallium oxides, Tin and/or Tin oxides, a quantity ranging from 1 ppm to 500 ppm with respect to the total weight of the catalytic composition of platinum and/or platinum oxides, and oxides of alkaline and/or alkaline earth metals.Type: ApplicationFiled: October 13, 2017Publication date: February 15, 2018Applicant: versalis S.p.A.Inventors: Rodolfo IEZZI, Giulio MANZINI, Paolo POLLESEL, Alessandro DEL SEPPIA
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Publication number: 20180043339Abstract: The present invention applies carbon nanotubes to catalyst particles, thereby providing catalyst particles which are usable in fluidized bed reactions, have high catalytic activity, and are easy to handle. The catalyst particles are carbon nanotube-coated catalyst particles which each comprise a carrier particle and a coating layer disposed on the surface of the carrier particle, wherein the carrier particles are flowable in fluidized beds and the coating layer comprises carbon nanotubes which have metal nanoparticles supported thereon and/or which have been doped with nitrogen or boron. The carbon nanotube-coated catalyst particles are flowable in fluidized bed reactions.Type: ApplicationFiled: March 1, 2016Publication date: February 15, 2018Applicant: NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITYInventors: Reiji NODA, Ryosuke ATSUMI, Kyoya WANIBUCHI
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Publication number: 20180043340Abstract: Disclosed are bulk metal oxide catalysts, and methods for their use, that include at 5 least two or more metals or two or more compounds thereof (M1, M2) and having an olivine crystal phase or a spinel crystal phase, or both phases, wherein the bulk metal oxide catalyst is capable of producing the H2 and CO from the CH4 and the CO2 under substantially dry conditions.Type: ApplicationFiled: January 27, 2016Publication date: February 15, 2018Inventors: Ugo Ravon, Lawrence D'Souza, Vinu Viswanath
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Publication number: 20180043341Abstract: The invention relates to the preparation of novel bi- or tri metallic silicate micro-porous and/or meso-porous materials based on cerium, nickel, copper and/or zinc on a porous silicate framework matrix to use its molecular sieve effect to target preferentially the acidic organic molecules present in hydrocarbon feedstocks like crude oil, bitumen, VGO and the like. The chosen metals are selected based on their ability to activate steam and transfer oxygen for completing the oxidation of carboxylic compounds or decarboxylating them. These composite materials can be prepared under hydrothermal synthesis conditions in order to produce suitable porous solids where the metals are well dispersed and preferentially distributed inside the channels of the silicate framework where they can interact only with the molecules that can go inside the channels.Type: ApplicationFiled: August 4, 2017Publication date: February 15, 2018Inventors: Pedro PEREIRA ALMAO, Gerardo VITALE-ROJAS, Maria Josefina PEREZ ZURITA, Lante Antonio CARBOGNANI, Ronald Scott SMITH, Clementina SOSA
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Publication number: 20180043342Abstract: An oxidation catalyst for treating an exhaust gas produced by a compression ignition engine comprising: a substrate; a catalytic material disposed on the substrate, wherein the catalytic material comprises platinum (Pt); and a region comprising a capture material, wherein the capture material comprises a Pt-alloying metal disposed or supported on a refractory oxide, wherein the refractory oxide comprises at least 65% by weight of zirconia, wherein the region is arranged to contact the exhaust gas after the exhaust gas has contacted and/or passed through the catalytic material.Type: ApplicationFiled: August 4, 2017Publication date: February 15, 2018Inventors: Yannick BIDAL, Andrew CHIFFEY, Francois MOREAU
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Publication number: 20180043343Abstract: A new crystalline aluminosilicate zeolite comprising a MTT framework has been synthesized that has been designated UZM-53. This zeolite is represented by the empirical formula: M+mRrAl1?xExSiyOz where M represents sodium, potassium or a combination of sodium and potassium cations, R is the organic structure directing agent or agents derived from reactants R1 and R2 where R1 is diisopropanolamine and R2 is a chelating diamine, and E is an element selected from the group consisting of gallium, iron, boron and mixtures thereof. Catalysts made from UZM-53 have utility in various hydrocarbon conversion reactions such as oligomerization.Type: ApplicationFiled: October 30, 2017Publication date: February 15, 2018Inventors: Christopher P. Nicholas, Mark A. Miller
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Publication number: 20180043344Abstract: To provide a process for producing an ion exchange membrane for electrolysis which has a low membrane resistance and which is capable of reducing the electrolysis voltage during the electrolysis, even if the membrane strength is increased, an ion exchange membrane for electrolysis, a precursor membrane of an ion exchange membrane for electrolysis, and an electrolysis apparatus.Type: ApplicationFiled: October 10, 2017Publication date: February 15, 2018Applicant: ASAHI GLASS COMPANY, LIMITEDInventors: Takayuki KANEKO, Hiromitsu KUSANO, Yasushi YAMAKI, Takuo NISHIO
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Publication number: 20180043345Abstract: An ion-exchange membrane is disclosed here including ion-permeable layers impregnated with an ion-exchange material and arranged in an order from one face of the membrane to the opposite face of the membrane such that opposing layers in the supporting membrane substrate provide sufficiently identical physical properties to substantially avoid irregular expansion when in a salt solution. The ion-permeable layers including at least one non-woven layer and at least one reinforcing layer.Type: ApplicationFiled: March 10, 2015Publication date: February 15, 2018Inventors: John H. BARBER, Russell James MACDONALD, Yongchang ZHENG, Kai ZHANG, Yonghong ZHAO
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Publication number: 20180043346Abstract: An ion exchange membrane is provided which includes an ion exchange polymer that is partially cross-linked. The partially cross-linked ion exchange polymer will be more stable and will not be washed out over time. The ion exchange polymer may be UV or chemically cross-linked, wherein a cross-linking compound is added to the ion exchange polymer either before or after coupling to a support material. A support material may be made of, or be coated with, a cross-linking compound and the support material may initiate cross-linking proximal to the support material. The support material may be made of a material that chemically bonds with the ionomer.Type: ApplicationFiled: August 10, 2017Publication date: February 15, 2018Inventors: Bamdad Bahar, Jack Saltwick, Xhefei Li
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Publication number: 20180043347Abstract: Biosafety units, methods of making and sealing the same are disclosed herein. The present invention includes a unitary structure able to be validated for pharmaceutical manufacturing comprising: at least one controlled air, sealable, sterilizable cleanroom; a mechanical system room adjacent to and separate from the cleanroom comprising: one or more air handling units that provide conditioned air to the cleanroom; and one or more power busses that provide power to electrical outlets in the cleanroom from two sources, wherein the at least two power supplies are connectable to one or more external electrical power sources; an integrated fire suppression system integral to the cleanroom; and one or more corridor connectors, wherein a corridor can be attached at the corridor connector.Type: ApplicationFiled: October 6, 2017Publication date: February 15, 2018Applicant: G-CON Manufacturing, Inc.Inventors: R. Barry Holtz, Troy Arledge, Phillip B. Maples, David M. Shanahan
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Publication number: 20180043348Abstract: A pipette is described having a tube, a pressure mechanism, and at least one reagent pad. The tube has a first end, a second end opposite the first end, and a sidewall extending between the first end and the second end, with the sidewall defining an interior cavity. The pressure mechanism is operably connected to the first end of the tube and is configured to enable a sample to be drawn into the interior cavity of the tube through the second end of the tube. The at least one reagent pad is positioned in the interior cavity of the tube and within a predefined liquid path whereby the sample contacts at least a portion of the at least one reagent pad when drawn into the interior cavity. In another embodiment, a pipette is described having a tube, a pressure mechanism, and a capillary positioned within the tube.Type: ApplicationFiled: October 23, 2017Publication date: February 15, 2018Applicant: Siemens Healthcare Diagnostics Inc.Inventor: James A. Profitt
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Publication number: 20180043349Abstract: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.Type: ApplicationFiled: October 25, 2017Publication date: February 15, 2018Applicant: Hamilton CompanyInventors: Jose Eduardo Guzman, Thomas Barresi, Dana A. Belton
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Publication number: 20180043350Abstract: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.Type: ApplicationFiled: October 25, 2017Publication date: February 15, 2018Applicant: Hamilton CompanyInventors: Jose Eduardo Guzman, Thomas Barresi, Dana A. Belton
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Publication number: 20180043351Abstract: Pipette tip coupler and a disposable pipette tip for a pipette device comprises a stepped coupler shoulder complementary to an axially stepped pipette tip shoulder; a plurality of circumferentially disposed elements or segments carried by the coupler at a location superior to the coupler shoulder; and a distal elastomeric element carried by the coupler at a location distal to the coupler shoulder wherein the plurality of elements or segments have a circumferential, radially translated state that provides an abutment with a first working surface formed in the interior surface of the tip while compressing the distal elastomeric element into sealing abutment with a second working surface formed in the interior surface of the tip and while abutting the proximally facing axial stop surface of the tip with the distally facing axial stop surface of the coupler to define an axial coupling position of the pipette tip on the pipette device.Type: ApplicationFiled: October 25, 2017Publication date: February 15, 2018Applicant: Hamilton CompanyInventors: Jose Eduardo Guzman, Thomas Barresi, Dana A. Belton
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Publication number: 20180043352Abstract: The present invention provides an improved method and device for preparing, extracting, separating and/or purifying a biomolecule, for example, nucleic acid from a biological sample. The device comprises a heat-deformable material, such that an inner chamber adopts a second configuration having a chamber volume less than the chamber volume of a first configuration, thereby expelling at least a part of a processed sample through a second opening from the device, and thereby recovering the biomolecule-containing composition.Type: ApplicationFiled: March 4, 2016Publication date: February 15, 2018Inventor: David James SAUL
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Publication number: 20180043353Abstract: Provided is a measurement container including a container body where a first region, a second region, and an intermediate region are continuously formed as an accommodation space accommodating a sample and an inlet is formed and a rotor which is arranged in the second region and rotated by an effect of magnetic force. The container body includes a wall portion which defines the accommodation space and at least a portion of which has a light transmitting property and a partitioning portion which partitions the intermediate region into one side and the other side in a second direction perpendicular to the first direction. The partitioning portion partitions the intermediate region into the one side and the other side so that a communication region which allows the one side and the other side to communicate with each other in the intermediate region remains.Type: ApplicationFiled: August 9, 2017Publication date: February 15, 2018Applicant: HAMAMATSU PHOTONICS K.K.Inventors: Kimiko KAZUMURA, Hiroshi TSUCHIYA
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Publication number: 20180043354Abstract: Provided is a container for preparing a diluted solution of a biological sample to be used for biological sample analysis. Specifically, provided is a container for specimen dilution, including: an open; a first bottom; a second bottom formed on an inner side wall of the container; and a groove upwardly formed, on the inner side wall of the container, from the second bottom, in which the groove has a constant width equal to a width of the second bottom, or the groove has, at a lower end thereof, a width equal to the width of the second bottom and upwardly widens.Type: ApplicationFiled: November 20, 2015Publication date: February 15, 2018Applicant: SEKISUI MEDICAL CO., LTD.Inventors: Kumiko YUKI, Hiroaki TAIRA
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Publication number: 20180043355Abstract: The disclosure provides compositions, kits and methods comprising an absorbent pad comprising a fibrous material and a liquid formulation comprising a luminescent substrate for identifying and quantifying biomolecule analytes.Type: ApplicationFiled: August 3, 2017Publication date: February 15, 2018Inventors: Surbhi DESAI, Kari SEVERSON
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Publication number: 20180043356Abstract: A device includes a microfluidic channel structure on a substrate and a first resistive structure on the substrate to control the temperature of at least the substrate. The first resistive structure is separate from, and independent of the, microfluidic channel structure. In some instances, the device includes a second resistive structure.Type: ApplicationFiled: January 30, 2015Publication date: February 15, 2018Applicant: Hewlett-Packard Development Company, L.P.Inventors: Chantelle Domingue, Manish Giri, Sadiq Bengali
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Publication number: 20180043357Abstract: Methods are provided for the large-scale high-content analysis of biological samples. In some embodiments, the methods are implemented in a reversed open microwell system that includes an array of open microwells, at least one microchannel, at least one input port and at least one output port In certain embodiments, the reversed open microwell system can be inserted in an automated management system which includes an incubator at controlled temperature, humidity and CO2 levels, a fluid dispensing system, and is capable of phase-contrast and fluorescence image acquisition. Also provided are kits for introducing fluids into a microfluidic device and systems for discharging one or more fluids in a microfluidic device.Type: ApplicationFiled: June 14, 2017Publication date: February 15, 2018Inventors: Massimo Bocchi, Andrea Faenza, Laura Rocchi, Dario Biscarini, Nicola Pecorari
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Publication number: 20180043358Abstract: Provided is a microfluidic chip. A microfluidic chip includes a main body portion and a first plunger. The main body portion includes a first fluid space for containing a first fluid and a first micro flow channel that is in communication with the first fluid space. The first plunger is capable of movement in the first fluid space so as to deliver the first fluid from the first fluid space to the first micro flow channel. According to the first aspect, a first fluid space for containing a first fluid such as a testing solution and a first plunger that delivers the first fluid from the first fluid space are provided. That is, a syringe composed of the first fluid space and the first plunger is provided, and it is therefore possible to deliver the first fluid by operating the syringe.Type: ApplicationFiled: July 21, 2017Publication date: February 15, 2018Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.Inventor: Kentaro FUJIMOTO
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Publication number: 20180043359Abstract: A method of manufacturing a microfluidic chip includes providing an upper mold having multiple upper ribs extending along a second direction, and a lower mold having multiple lower ribs extending along a first direction different from the second direction, forming a forming material in a filling space defined by the upper and lower molds to provide a channeled plate having multiple upper microfluidic channels complementary in shape to the upper ribs, lower microfluidic channels complementary in shape to the lower ribs, and multiple thin film valves formed at intersections where the upper microfluidic channels intersect the lower microfluidic channels, separating the upper and lower molds, and covering the lower and upper microfluidic channels.Type: ApplicationFiled: August 7, 2017Publication date: February 15, 2018Applicant: Taiwan Green Point Enterprises Co., Ltd.Inventors: Yi-Cheng LIN, Sung-Yi YANG
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Publication number: 20180043360Abstract: According to one embodiment of the present invention, a sealing device of a microfluidic chip and an operation method therefor are provided. The device can comprise: a support part in which the microfluidic chip is arranged; and a heat sealing part applying heat to an inlet part and an outlet part of the microfluidic chip so as to seal the inlet part and the outlet part.Type: ApplicationFiled: October 27, 2015Publication date: February 15, 2018Inventors: Sung Woo KIM, Jae Young BYUN, Jung Hwan LEE, Duck Joong KIM, Jun HUR, Eun Sub KIM, Song Gyun JUNG
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Publication number: 20180043361Abstract: An analysis device for a liquid sample comprising: one microfluidic analysis channel made of a wicking material with adequate porosity to allow capillary flow of at least one liquid sample suitable for generating electricity, at least one receiving absorbent region coupled to the microfluidic analysis channel, at least one collecting absorbent region coupled to the microfluidic analysis channel, a cathodic zone coupled to the microfluidic analysis channel, an anodic zone coupled to the microfluidic analysis channel, and at least one detection zone having a sensor, where each receiving absorbent region and each collecting absorbent region are coupled to the microfluidic analysis channel such that when a fluid suitable for generating electricity is deposited in the receiving absorbent region, it flows by capillary action through the microfluidic analysis channel to reach the collecting absorbent region where it is absorbed, and where the sensor interacts with the sample when the latter flows by capillary througType: ApplicationFiled: October 23, 2017Publication date: February 15, 2018Applicants: Consejo Superior de Investigaciones Cientificas (CSIC), Institucio Catalana de Recerca i Estudis Avancats (ICREA), FUELIUMInventors: Maria de les Neus Sabate Vizcarra, Juan Pablo Esquivel Bojorquez, Sergi Gasso-Pons
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Publication number: 20180043362Abstract: A fluid exit passage is at a location along a microfluidic channel. A fluid displacement device is proximate the location along the microfluidic channel. A constituent locator distinguishes a target constituent in a fluid within the microfluidic channel from remaining non-target constituents and locate the target constituent proximate the fluid exit passage. A controller selectively actuates the fluid displacement device when the target constituent is proximate the fluid exit passage to discharge the target constituent from the microfluidic channel through the fluid exit passage.Type: ApplicationFiled: April 30, 2015Publication date: February 15, 2018Applicant: Hewlett-Packard Development Company, L.P.Inventors: Anita Rogacs, Alexander Govyadinov
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Publication number: 20180043363Abstract: Described is an automated reagent dispensing cap and methods of use in an automated clinical analyzer for introducing one or more reagent components housed in the reagent dispensing cap into a container enclosing another reagent component with which it is combined to achieve a reagent useful for diagnostic testing.Type: ApplicationFiled: August 11, 2016Publication date: February 15, 2018Inventors: Gert Blankenstein, Hansong Zeng