Abstract: A lactic acid measurement device includes a stimulus-responsive gel in the form of a gel which reacts with lactic acid contained in sweat and changes its impedance, an electrical property detection part which detects the impedance of the stimulus-responsive gel, and a concentration estimation part which estimates the concentration of lactic acid contained in sweat from the time-series change in the impedance.

Abstract: Biosensor devices and methods of forming the same are provided. A cavity is formed in a substrate and is configured to receive one or more charged molecules. A transistor is formed in the substrate and includes a source region, a drain region, and a channel region that are spatially separated from the cavity in a lateral direction. A gate of the transistor is disposed below the cavity and extends between the cavity and the source, drain, and channel regions. A voltage potential of the gate is based on a number of the charged molecules in the cavity.

Abstract: Electrochemical and bio sensors using metal oxide semiconductors and method of making the same are described herein. The sensor includes a gate electrode, a dielectric layer over the gate electrode, a channel layer over the dielectric layer, and source and drain electrodes formed on the channel layer to provide a field effect transistor structure. The channel layer is a metal oxide semiconductor film that has a substantially uniform thickness of at least 3 nm thick and less than 10 nm thick. The metal oxide semiconductor film is functionalized with molecules attached thereto that are open to make contact with a fluid for detection of at least one component or at least one physical or chemical property of the fluid.

Abstract: An ion sensor for sensing ions in a fluid includes a Metal-Oxide Semiconductor (MOS) varactor formed in and on a semiconductor substrate having a gate dielectric over the semiconductor substrate, a gate over the gate dielectric, a well region in the substrate under the gate dielectric, and source/drain regions in the well region, wherein the well region and the source/drain regions are of a same conductivity type; and a sense electrode coupled to the MOS varactor, wherein the capacitance of the gate dielectric of the varactor changes when the sense electrode interacts with ions in the fluid. Alternatively, resistance of the well region changes when the sense electrode interacts with ions in the fluid, affecting a change in a quality factor of an inductor.

Abstract: A molecular detection apparatus according to an embodiment includes a detector and a discriminator. The detector includes a plurality of detection cells, where the plurality of detection cells include at least an organic probe containing a cyano group or a nitro group as a neighboring group of a reactive group. The discriminator discriminates a substance to be detected by signal patterns of the plurality of detection cells.

Abstract: A method and devices for controlling a potentiostat control loop circuit to provide an accurate cell voltage for electrochemically sensing a sample, wherein the cell voltage corresponds to a difference between electrode voltages a a working electrode and a reference electrode of a three-electrode potentiostat are provided. The devices include a potentiostat control loop circuit having a first amplifier with an output connected to a counter electrode of the three electrode potentiostat and a first input connected to a first potential and a first switched capacitor network including a first capacitance device having a first electrode connected to a second input of the first amplifier. The first switched capacitor network is also operatively connected to the first amplifier for operating in a first mode and a second mode t switchably couple the second input of the first amplifier to the reference electrode of the three-electrode potentiostat.

Abstract: Provided is an electrophoresis device that, by electrophoresis, feeds a sample into capillaries and optically detects the sample, the electrophoresis device being provided with capillaries, a capillary head provided at the distal end of the capillaries, a phoretic medium-filled container used for electrophoresis and filled with a phoretic medium, a guide member that covers the side surface of the phoretic medium-filled container, a seal member that seals from below the phoretic medium filled in the phoretic medium-filled container, and a plunger that presses the seal member.

Abstract: An electrowetting on dielectric device includes: (a) a first substrate comprising electrodes at a surface of the first substrate configured to effect electrowetting mediated droplet operations; (b) a second substrate spaced from the surface of the first substrate to define an interior volume between the first substrate and the second substrate; (c) a liquid droplet disposed in the interior volume; and (d) a filler fluid disposed in the interior volume and surrounding the liquid droplet, wherein one or both of the liquid droplet and filler fluid contains a surfactant, the surfactant comprising a siloxane group represented by the structural formula: where n?1.

Abstract: A method for determination of an unknown analyte using quantitative electrochemical generation of a detectable species, which provides specified quantities of the species, is described. As an example, free chlorine concentration measurements may be performed using N,N-Diethyl-p-phenylenediamine (DPD), or N,N-bis(2,4-di-sulfobenzyl)toluidinetetrasodium salt (SBT), for obtaining an in-situ calibration curve, whereby matrix effects are eliminated.

Abstract: A discharge ionization current detector for ionizing and detecting a sample component where the sample component is ionized by UV light is provided. The detector includes a UV light source, and a microfluidic channel having a first surface including a conducting or semiconducting material and an opposing second surface including a conducting or semiconducting material, one of the first surface and the second surface being a collection electrode and the other of the first surface and the second surface being a bias electrode, the microfluidic channel being configured to receive a sample component. The microfluidic channel is in fluid communication with the UV light source such that, when activated, UV light from the UV light source can enter the microfluidic channel and ionize the sample component, which releases an electron, and the ionized sample component and electron are detected by the collection and bias electrodes.

Abstract: An ultra-miniature and micro-powered system, apparatus, and method utilizing electromagnetic imaging via minute eddy currents, analog circuit averaging and artifact cancellation, that attaches to the outside of clothing and measures internal bodily functions including but not limited to heart rate, respiration rate, and wetness of underclothing

Abstract: A system for determining whether a magnetic field associated with an elongate rebar element in a concrete body of a reinforced structural element assembly includes one or more anomalies. The system includes a data-gathering unit having a frame assembly movable relative to the reinforced structural element assembly, and a sensor assembly mounted to the frame assembly. The sensor assembly includes one or more magnetic sensors for sensing at least part of the magnetic field as the sensor assembly is moved relative to the concrete body, to generate magnetic field data defining magnetic flux density of the magnetic field of the rebar element. The system also includes a tracking assembly for generating location data to locate the magnetic field data relative to the concrete body, and a processor for analyzing the magnetic field data and the location data to generate anomaly data describing the anomaly.

Abstract: Methods, systems, and devices for solid axle testing are provided.

Abstract: An apparatus for detecting anchor bolt pullout strength. The apparatus includes circuitry configured to process ultrasonic measurement signals using at least one of a direct, an indirect, and a semi-direct measurement technique. Further, the apparatus comprises a first probe and a second probe connected to the circuitry, and memory for storing data detected by the first and the second probe. The memory is connected to the circuitry and a data connection connected to the circuitry and configured to communicate with an external network. An ultrasonic signal is transmitted by the circuitry through the first probe and rebounded by the second prob. The circuitry detects a time duration to receive the rebounded signal, storing the time duration to the memory, and comparing the time duration to reference measurement data. The reference measurement data may be stored in at least one of the memory and the external network.

Abstract: The invention relates to a method for detecting defects of at least one metal wire of a set of metal wires, in particular in a cable, the method including: a step of emitting a high-frequency ultrasound signal around a so-called specific frequency in the metal wire; a step of reflecting said ultrasound signal in the metal wire; and a step of receiving the reflected ultrasound signal. The emitted ultrasound signal enables the energisation of at least one high-frequency wave capable of propagating in a longitudinal direction of the metal wire and having a phase velocity that is slightly higher than a compression volume wave velocity in the metal from which the metal wire is made.

Abstract: A holder for attaching an acoustic emission sensor to a non-metallic and non-magnetic material has a tubular body with a closed top end and an open bottom end through which the sensor is insertable into the tubular body. The closed top end has a plurality of unitary flexible flaps angularly extending inwardly from an inner surface of the enclosed top end. An inner surface of the tubular body has a plurality of spacers extending radially inward proximate the bottom end of the tubular body. The unitary flexible flaps and the spacers fix the sensor within the tubular body. The tubular body may also have a plurality of capture tabs extending outwardly from an exterior surface thereof proximate the open bottom end that are slidably and removably engageable with an engagement keyway in a retainer bracket that is affixed to a non-metallic and non-magnetic material.

Abstract: A system for nondestructive evaluation of a test object includes a platform, an electromagnetic acoustic transducer (EMAT) to create acoustic vibrations that travel along the test object; an infrared detector positioned to record thermal images of a plurality of test areas on the test object to detect flaws in the test object as the platform and the test object move relative to each other; and a control connected to actuate the EMAT and the infrared detector, synchronize the creation of vibrations with the recording of thermal images, receive a signal from the infrared detector indicative of the thermal image of the surface of the test object, and record locations of the flaws appearing on the thermal images of the test areas, all as the platform and the test object move relative to each other.

Abstract: A gas analyzer is provided. The gas analyzer may include: a tubular housing having a housing wall extending along an axial direction of the tubular housing and surrounding a gas chamber configured to receive a gas to be analyzed therein, an excitation element positioned at a first axial end of the tubular housing and configured to selectively excite gas molecules of a specific type that is to be detected in the gas received in the gas chamber in a time-varying fashion, thereby generating acoustic waves, and a sensor positioned at a second axial end of the tubular housing and configured to detect acoustic waves generated by the excitation element.

Abstract: An ultrasonic device includes: a substrate provided with a first opening and a second opening; a support film that is provided on the substrate and closes the first opening and the second opening; a transmitting piezoelectric film that is provided on the support film at a position which overlaps the first opening when viewed in a thickness direction of the substrate and that is sandwiched between a pair of electrodes in the thickness direction of the substrate; and a receiving piezoelectric film that is provided on the support film at a position which overlaps the second opening when viewed in the thickness direction of the substrate and that is sandwiched between a pair of electrodes in an intersecting direction intersecting with the thickness direction of the substrate.

Abstract: This invention relates to a movable article inspection system and inspection method, wherein the inspection system comprises: a first automated guided vehicle, a radiation source and a detection mechanism; said radiation source and said detection mechanism are both mounted on said first automated guided vehicle, said first automated guided vehicle is able to move to a preset scanning inspection position, such that scanning inspection of said article to be scanned is effectuated by means of relative movement between an article to be scanned and the first automated guided vehicle. Such movable inspection system based on an automated guided vehicle is capable of making full use of an existing automated guided vehicle and its control system to make a movement path of the inspection system more flexible, and capable of effectuating centralized control and management of the inspection system, so that it can improve inspection efficiency, and save labor cost.

Abstract: A method for monitoring quality of a hydraulic fluid in an electro-hydraulic (EH) valve is disclosed. The method includes applying predetermined signal to a solenoid coil, surrounding a pusher pin in EH valve, to facilitate oscillation of a pusher pin in EH valve to change static friction between the pusher pin and a cavity of EH valve, to dynamic friction. EH valve includes a housing defining the cavity having an end wall. Cavity slidably receiving the pusher pin having a first end and a second end. The hydraulic fluid is received between the first end of the pusher pin and the end wall. The oscillation of the pusher pin generates an acoustic wave that propagates through the hydraulic fluid. The method further includes determining the quality of the hydraulic fluid based on one or more characteristics of the acoustic wave detected by an acoustic sensor positioned on the end wall.

Abstract: An apparatus and a method for measuring one or more acoustic parameters in a duct are described. The method includes arranging at least one pair of microphones in an array on a microphone support device, disposing the microphone support device including the array of microphones in the duct, generating an acoustic signal in the duct such that the acoustic signal propagates toward the array of microphones, and receiving by the array of microphones, the acoustic signal to provide a microphone output signal. The microphone support device is configured to fit within an inner diameter of the duct.

Abstract: A sample injector for chromatography 10 where air or moisture can be prevented from getting mixed in when a sample is injected is provided with a syringe 11, a syringe drive unit 13, a turret 12 in which sample vials 4 are placed, a turret drive unit 14, and a control unit 30 that controls the syringe and turret drive units 13 and 14. The configuration includes a housing 15 having a gas introduction port 15a and a gas discharge port 15b that communicate with the inner space, where the syringe 11 sucks a sample from a sample vial 4, the sucked sample is injected into the sample vaporizing chamber 23 in a chromatograph 20, and a predetermined gas is introduced through the gas introduction port 15a, and at the same time, a predetermined gas is discharged through the gas discharge port 15b when a sample is analyzed.

Abstract: A high performance liquid chromatography method for analysis of a MN diagnostic and therapeutic ligand and precursors is revealed. Polarity of eluents used during elution is changed to remove impurities. First use a first eluent with a lower ratio of acetonitrile as a mobile phase to elute analytes. Then a second eluent in which a ratio of acetonitrile is increased into 97˜99% is used to elute the analytes for at least 20 minutes. Next use the first eluent to elute the analytes for at least 60 minutes. Thus no residual impurities are left in the column and the analytes remain in the column stably. Therefore a more accurate and reproductive result is obtained.

Abstract: A fitting for providing a fluid connection between a capillary and a fluidic conduit of a fluidic component, wherein the fitting comprises a capillary reception configured for receiving the capillary, a force applicator configured for being operable to apply a fixing force for fixing the capillary within the fitting, a force limitation mechanism configured for limiting the fixing force being applicable by the force applicator to the capillary, a force splitter configured for splitting the fixing force into an advance force component for advancing the capillary received in the capillary reception towards the fluidic component and into a clamping force component for clamping the capillary received in the capillary reception within the fitting, and a biasing mechanism particularly arranged between the force applicator and the force splitter and configured for biasing the force splitter against the capillary.

Abstract: A method is provided for more easily detecting and quantifying a protein by regioselectively digesting a variable region of an Fab domain of a monoclonal antibody while suppressing proteolysis of an Fc domain. In the method, a porous body in which a monoclonal antibody is immobilized in pores and nanoparticles on which a protease is immobilized are brought into contact with each other in a liquid to perform selective proteolysis of the monoclonal antibody, and a resulting peptide fragment is detected using liquid chromatography-mass spectrometry (LC-MS), and a peptide having an amino acid sequence that includes an amino acid derived from a CDR2 region of a heavy chain or a light chain of the monoclonal antibody is detected.

Abstract: Provided is an amine group-derivatized composition including a Boc compound for liquid chromatography-mass spectrometry (LC-MS) analysis, and when the amine group-derivatized composition is used in analysis using reverse-phase LC-MS, it is possible to effectively analyze compounds including an amine group and an amino acid at a low cost in a short time.

Abstract: A method of analyzing a multi-component polymer comprising: (a) dissolving an multi-component polymer having a primary monomer and primary comonomer to form a first volume (soluble portion of multi-component polymer); (b) injecting a portion of the first volume into a chromatographic column to get elution first slices, leaving a second volume behind; (c) filtering the second volume to isolate multi-component polymer solids; (d) dissolving solids to form solution third solution (insoluble portion of multi-component polymer); (e) injecting a portion of third solution into the chromatographic column to get elution second slices; (f) obtain infra-red spectra at wavelengths suitable for the primary monomer and the primary comonomer of first and second elution slices, separately; and (g) for each elution slice, separately calculate: (i) the different polymer components (soluble and insoluble); and (ii) the comonomer content of each component (soluble and insoluble).

Abstract: An apparatus and method for measuring hydrogen peroxide concentration in water to an accuracy of 0.1 ppm comprises a colorimetric assay method to determine hydrogen peroxide concentration. The assay is monitored spectophotometrically at a desired wavelength. Each sample is corrected relative to a control sample and hydrogen peroxide concentration determined with respect to a standard curve.

Abstract: Various samples are generated on a substrate. The samples each includes or consists of one or more analytes. In some instances, the samples are generated through the use of gels or through vapor deposition techniques. The samples are used in an instrument for screening large numbers of analytes by locating the samples between a working electrode and a counter electrode assembly. The instrument also includes one or more light sources for illuminating each of the samples. The instrument is configured to measure the photocurrent formed through a sample as a result of the illumination of the sample.

Abstract: A method and an apparatus are provided for calibrating a particulate matter measurement value. The method includes: when a current particulate matter measurement value is obtained, obtaining a current temperature-humidity parameter; obtaining a particulate matter measurement deviation value corresponding to the current temperature-humidity parameter from pre-stored particulate matter measurement deviation values under various temperature-humidity parameters according to the current temperature-humidity parameter; and calibrating the current particulate matter measurement value according to the particulate matter measurement deviation value corresponding to the current temperature-humidity parameter.

Abstract: A highly sensitive carbon-nanomaterial-based gas sensor for use in high-humidity environments and a method of improving the sensitivity thereof, the gas sensor being configured such that a functional group for binding to a water molecule is formed on the surface of a first detector composed of a carbon nanomaterial, whereby a hydronium ion (H3O+) is produced and thus an additional ion conduction path is formed, thereby obtaining an additional reaction path in high-humidity environments, ultimately improving the sensitivity and detection threshold of the sensor. The gas sensor includes a substrate, a first detector disposed on the substrate, electrodes electrically connected to the first detector, and a second detector disposed on the first detector, wherein the second detector has a hydrophilic functional group.

Abstract: Systems and methods for measuring gas flux are disclosed. One method for calculating gas flux includes: receiving a master clock signal from a global positioning system (GPS) module; transmitting a clock synchronization signal that is based on the master clock signal to a measurement subsystem configured to measure environmental data, wherein the measurement subsystem comprises at least two clocks; receiving the environmental data from the measurement subsystem, wherein the environmental data is associated with the at least two clocks; and calculating gas flux based on the environmental data received from the measurement subsystem.

Abstract: The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.

Abstract: The invention relates to a candling apparatus for the rapid discrimination, removal and relocation of non-live avian eggs. The invention further relates to methods of use of the candling apparatus for the candling, removal and relocation of avian eggs.

Abstract: A device may receive a classification model generated based on a set of spectroscopic measurements performed by a first spectrometer. The device may store the classification model in a data structure. The device may receive a spectroscopic measurement of an unknown sample from a second spectrometer. The device may obtain the classification model from the data structure. The device may classify the unknown sample into a Kosher or non-Kosher group or a Halal or non-Halal group based on the spectroscopic measurement and the classification model. The device may provide information identifying the unknown sample based on the classifying of the unknown sample.

Abstract: The present invention provides a water quality analysis system capable of making multiple simultaneous measurements of different water quality parameters and saving or transmitting this data for analysis. A housing surrounds a data processor and a water sensor flow cell. The flow cell incorporates a channel through which a stream of water flows. Multiple probe bores within the flow cell house different sensor probes used to measure different water quality parameters of the stream. The data processor receives and digitizes data for the different water quality parameters.

Abstract: Methods and reagents are disclosed for improved detection of inorganic oxidizers, such as but not limited to chlorates, perchlorates, permanganates, dichromates, and osmium tetraoxides. In one aspect of the invention, latent acid-generating reagents are employed that are chemically stable at room temperature but undergo an acidic transformation when exposed to an elevated temperature or radiation. The latent reagent can be activated by heat or radiation (e.g., UV radiation). The resulting acidic reagent can then transfer a proton to the anion (i.e., chlorate, perchlorate, etc.) of the target analyte, forming an acid (i.e., chloric acid, perchloric acid) that is more easily vaporized and, hence, more easily detected. In another aspect of the invention, heat-sensitive inorganic salts and/or photosensitive onium salts are disclosed as reagents to carry out this method.

Abstract: Certain embodiments of the disclosure relate to a bi-directional oil-flow adapter that is attachable to a valve-controlled port of a transformer housing in which oil is contained for cooling parts of the transformer such as a primary coil and a secondary coil. The bi-directional oil-flow adapter not only allows for an oil sample to be drawn out of the transformer housing via the valve-controlled port but also allows for the oil sample to be used (along with an additional volume of oil if so desired) for flushing the valve-controlled port in order to ensure that a subsequent oil sample is different than a current oil sample. The oil sample can be provided to a dissolved gas analyzer for detecting and analyzing one or more gases that may be present in the oil sample, the one more gases indicative of a level of contamination of the oil sample.

Abstract: A method and system for detecting mercury in a hydrocarbon-containing fluid stores a sample of the hydrocarbon-containing fluid in a first reservoir. A liquid phase reagent solution is stored in a second reservoir. The liquid phase reagent solution includes nanoparticles with an affinity to mercury, wherein the nanoparticles are suspended as a colloid in the liquid phase reagent solution. The sample of the hydrocarbon-containing fluid is delivered from the first reservoir into a first port of a fluidic device while the liquid phase reagent solution is delivered from the second reservoir into a second port of the fluidic device such that the fluidic device produces slug flow. The slug flow is subject to optical analysis that determines concentration of mercury in the sample of the hydrocarbon-containing fluid.

Abstract: The present disclosure provides compositions, methods, and systems for identifying marked hydrocarbon fluids. These compositions, methods, and systems utilize a gas chromatography marker including a pyrrolidinone. The methods and systems can identify the presence or absence of the gas chromatography marker and/or the pyrrolidinone. The compositions, methods, and systems can optionally utilize a spectroscopic marker.

Abstract: Disclosed are fibers which contain identification fibers. The identification fibers can comprise one or more chemical markers, or taggants, which may vary among the fibers or be incorporated throughout all of the fibers. The disclosure also relates to the method for making and characterizing the fibers. Characterization of the fibers can include identifying chemical markers and correlating the chemical markers and a taggant chemical marker amounts of at least one of the chemical markers to manufacturer-specific taggants to determine supply chain information. The supply chain information can be used to track the fibers from manufacturing through intermediaries, conversion to final product, and/or the consumer.

Abstract: A sensor assembly comprises a substrate arrangement and a sensor chip mounted to the substrate arrangement. A sensing element is integrated on or in the sensor chip and is sensitive to at least one parameter of a fluid. An access opening is provided in the substrate arrangement enabling the fluid to access the sensing element. A metallization arranged on at least a portion of the substrate arrangement seals a chamber containing the sensor chip which portion comprises one or more of a wall defining the access opening or an area facing the sensor chip.

Abstract: A hand-held test meter for use with an analytical test strip for the determination of an analyte in a bodily fluid sample includes a test meter housing with a housing outer surface and a distal end, a PCB disposed within the test meter housing; a SPC disposed in the test meter housing, and a metal shield plate securely attaching the strip port connector to the PCB. The SPC includes a SPC housing with at least one contact stopper rib, and plurality of electrical contacts (e.g., electrical contacts with a T-bar shaped distal end) disposed in the SPC housing. Each of the plurality of electrical contacts has a distal end and a test strip contact surface (TSCS). The TSCS of the electrical contact is configured for operable contact with an analytical test strip received in the SPC and the TSCS of the electrical contact is a smooth dimpled surface.

Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Abstract: In the method of preparing a sample for analysis, a reaction is performed that produces different modified product depending on the sialic acid linkage type when a sialic acid is bound to a sugar chain of an analyte. In this reaction, an analyte containing a sugar chain, an amine containing two or more carbon atoms, and a dehydration-condensation agent are used. The sialic acid linkage type can be identified by analyzing the resulting sample with mass spectrometry etc. This method is applicable not only to free sugar chains but also to glycopeptides and glycoproteins.

Abstract: This disclosure relates to predicting the carcinogenicity of compounds. More in particular, this application discloses methods to detect whether a compound is a non-genotoxic carcinogen and methods to discriminate between genotoxic and non-genotoxic carcinogens based on in vivo stem cell proliferation patterns in flatworms.

Abstract: Provided herein are methods of detecting responses of bio-artificial tissues to agents by performing assays using three-dimensional bio-artificial tissues. The methods are adaptable to high-throughput platforms.

Abstract: High-throughput methods of screening agents for activities affecting renal, cardiac, blood or lymphatic vascular development and functions in amphibians in multiwell plates are provided. Also provided are novel compounds that modulate blood and lymphatic vascular development.

Abstract: This disclosure describes an electric-field imaging system and method of use. In accordance with implementations of the electric-field imaging system, a fluid sample can be placed on top of a pixel-based impedance sensor. An image of the target analytes can be created immediately afterwards. From this image, computer imaging algorithms can determine attributes (e.g., size, type, morphology, volume, distribution, number, concentration, or motility, etc.) of the target analytes. The electric-field imaging sensor can be used for a variety of agglutination or agglomeration assays.