Abstract: A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together to provide a composite image. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the composite image generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as transparent on the composite image. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices.

Abstract: A liquid distribution system is configured to deliver a disinfectant solution to a medical device within an enclosure. A disinfectant concentration measuring subsystem includes a mixing chamber, a reservoir, a reservoir cap, a pump, and a concentration analysis assembly. The first mixing chamber is in fluid communication with an outlet of the liquid distribution system. The reservoir is configured to contain a reagent solution and is in fluid communication with the mixing chamber. The reservoir cap includes a static member, which is configured to couple with a supply conduit and a return conduit; and a rotating member, which is configured to rotate relative to the static member to couple the reservoir cap with the reservoir. The pump is configured to simultaneously pump the disinfectant solution and the reagent solution into the mixing chamber. The concentration analysis assembly is operable to determine a concentration of disinfectant output from the mixing chamber.

Abstract: A monitor/display is used to display a vision test. A patient is spaced a predetermined distance from the monitor/display during the testing procedure, and individual, multiple LED housings are equally spaced about a center point of the monitor/display to direct light toward the patient during at least a portion of the test procedure. The light emanating from the individual housings is a diffuse, unfocused light to simulate glare, and the intensity of the light may be selectively altered. Conducting vision testing under glare conditions determines if there is any reduction or fall off in the patient's vision under such circumstances and provides an indication of whether the patient may require cataract surgery or has another ocular problem. An assembly allows an existing vision testing system to be easily modified to provide glare light testing capabilities.

Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view 10 afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.

Abstract: An ophthalmic surgical apparatus includes an observation optical system, an illumination optical system, an interference optical system, and an image forming unit. The observation optical system is configured to observe an eye through an objective lens. The illumination optical system is configured to illuminate the eye through the objective lens. The interference optical system includes a reference optical path and a signal optical path which leads to the eye through the deflecting member located between the objective lens and the eye, and is configured to detect interference light based on light having passed through the signal optical path and returning from the eye and the reference light having passed through the reference optical path. The image forming unit forms an image of the eye based on a detection result obtained by the interference optical system.

Abstract: A method for detecting the viewing direction of a person having a visual aid includes providing at least one optical property of a visual aid of the person, observing at least one eye of the person, and correcting data ascertained from the observation based on the at least one optical property of the visual aid. An apparatus designed to detect the viewing direction of a person includes an observation device set up to observe at least one eye of the person, a data record containing at least one optical property of a visual aid of the person, and a computing device equipped to correct the observation based on the data record.

Abstract: A method, which is for assessing drowsiness of a subject over a period of time, includes the steps of: acquiring gaze and blink measurements of the subject over a period of time; and statistically comparing the measurements against a plurality of gaze and blink measurements, which have been correlated to alertness, in order to produce a value representative of alertness/drowsiness.

Abstract: Optical coherence tomography (OCT) may be used to acquire cross-sectional or volumetric images of any specimen, including biological specimens such as the retina. Additional processing of the OCT data may be performed to generate images of features of interest. In some embodiments, these features may be in motion relative to their surroundings, e.g., blood in the retinal vasculature. In some embodiments, an acquired image may be degraded by motion artifact. The proposed invention describes OCT system embodiments that may be configured for multi-scale imaging, with the capability of switching between low or high lateral resolution, and with the assistance of adaptive optics for aberration correction. The invention also describes a method for enhancing OCT image quality by reducing or eliminating the negative effects introduced by sources and speed by performing bidirectional scanning.

Abstract: An ophthalmic surgical microscope includes an observation optical system configured to guide observation luminous fluxes for a right eye and a left eye from an observation object to an imaging device, an actuator configured to move a position of the observation optical system in at least a direction intersecting with the observation luminous fluxes, a processor, and a memory storing computer-readable instructions. The computer readable instructions, when executed by the processor, cause the ophthalmic surgical microscope to cause a stereoscopic image display to display an observation image to be observed with a right eye of a user and an observation image to be observed with a left eye of the user, detect a position of the observation object with respect to the observation optical system, and correct a deviation in a relative position of the observation optical system with respect to the observation object.

Abstract: An extended medical test system provides a user-friendly apparatus that can be used to perform a plurality of diagnostic functions. In an example of an eye examination system, the system is configured to capture one or more patient images containing a patient's eye and a surrounding body portion, and perform additional diagnostic functions as well as the eye examination.

Abstract: An ophthalmic apparatus and method is provided for quickly and accurately aligning a measurement optical system with the vertex of the cornea of a subject's eye. The ophthalmic apparatus comprises a main body, an infrared detection system, a support portion, a driving unit, a visible light irradiation system placed coaxially with the apparatus main body and configured to irradiate the subject's eye, at least two photographing devices configured to substantially simultaneously photograph the subject's eye from different directions, a first alignment detection unit configured to acquire Purkinje images of the subject's eye, originating from infrared light, from at least two photographed images of the subject's eye and detect a position of the subject's eye from the Purkinje images, a second alignment detection unit, and a drive control unit to align the apparatus with the subject's eye.

Abstract: A wound dressing device with reusable electronics for wireless monitoring and a method of making the same are provided. The device can be a smart device. In an embodiment, the device has a disposable portion including one or more sensors and a reusable portion including wireless electronics. The one or more sensors can be secured to a flexible substrate and can be printed by non-contact printing on the substrate. The disposable portion can be removably coupled to the one or more sensors. The device can include one or more sensors for wireless monitoring of a wound, a wound dressing, a body fluid exuded by the wound and/or wearer health.

Abstract: A medical inspection apparatus which is capable of communicating with an external device storing at least one piece of subject information of a subject and at least one piece of subject information update time information indicating an update time of the subject information and which inspects the subject to generate inspection data, the medical inspection apparatus including: an acquisitor which acquires the last updated subject information and the subject information update time information corresponding to the last updated subject information at a timing of execution of a predetermined operation input; and a setter which sets the acquired subject information as the subject information of an inspection target subject when it is within a predetermined time from the acquired subject information update time information.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: A transmission apparatus for the transmission of brain parameter sensor data includes, a receiving unit with an antenna, which can be wirelessly connected to a transmitting unit of a brain parameter sensor for data transmission, a data processing device which is in signaling connection to the receiving unit, a high frequency source for generating a data transmission carrier frequency, wherein the high frequency source is integrated in a housing of the data processing device. The result is a transmission apparatus which is designed for use in a domestic patient environment.

Abstract: Method and system for providing diabetes management is provided.

Abstract: A contactless system for measuring and continuously monitoring arterial blood pressure includes a light source configured to illuminate light having at least one predetermined wavelength at a predetermined area of a human subject having an artery therein. A detector responsive to reflected light from the predetermined area is configured to continuously acquire images of the artery in the predetermined area.

Abstract: An image processing apparatus of the invention is for generating a tomographic image corresponding to a cross-section of an imaging object. The image processing apparatus 1 comprises: a data acquisitor 20 which obtains image data corresponding to a plurality of imaging with respect to the imaging object; and an image generator 30 which generates the tomographic image corresponding to the cross-section parallel to the depth direction based on the image data. The plurality of imaging are performed with mutually different focus positions in a depth direction and imaging ranges overlapped in the depth direction. The image generator 30 sets a value of each pixel in the tomographic image at a value obtained by a calculation process between the image data of a same position of the imaging object corresponding to the pixel obtained at each of the plurality of imaging.

Abstract: A method for detecting fluid injection in a patient, the method including the steps of providing a fluid storage tank; providing fluid for use in machinery and adding said fluid to the fluid storage tank; and providing a fluorescent dye and adding the fluorescent dye to the fluid such that the fluid fluoresces in the presence of ultraviolet light.

Abstract: Provided is an in vivo bioimaging method including irradiating near-infrared (NIR) light onto a living body, converting the NIR light passed through the living body, into visible light using upconversion nanoparticles (UCNPs), and generating a bioimage of the living body by receiving the visible light using a complementary metal-oxide-semiconductor (CMOS) image sensor.

Abstract: A non-invasive, optical method and device for the detection of melanoma in skin lesions. The detection of the presence of melanoma is accomplished optically by looking for specific changes (signatures) in the spectrum of optical light elastically scattered off melanoma molecules. Elastic scattering spectroscopy (ESS) converts subcellular morphological changes into scattering spectrum signatures. A melanoma discrimination analysis is performed by illuminating the lesion with a handheld device that also collects a portion of the scattered light, converts it into digital signals, analyzes the requisite spectral signatures, and provides a logical output showing the user the presence (or absence) of melanoma in the subject lesion.

Abstract: An apparatus or a system may include an ultrasonic sensor array, a radio frequency (RF) source system and a control system. Some implementations may include a light source system and/or an ultrasonic transmitter system. The control system may be capable of controlling the RF source system to emit RF radiation and of receiving signals from the ultrasonic sensor array corresponding to acoustic waves emitted from portions of a target object in response to being illuminated with the RF radiation. The control system may be capable of acquiring ultrasonic image data from the acoustic wave emissions received from the target object.

Abstract: A photoacoustic apparatus is used that has: a detecting unit that detects photoacoustic waves generated by an object containing contrast agent in first blood vessels of circulating blood and in second blood vessels; and a signal processing unit that generates contrast agent distribution and acquires contrast agent concentration change in the circulating blood. The signal processing unit acquires the position of the first blood vessels on the basis of a time-series change of the contrast agent distribution and the contrast agent concentration change, and lowers the concentration at the position of the first blood vessels on the basis of the contrast agent distribution.

Abstract: A temperature probe includes a handle and a shaft extending from the handle. The shaft includes a distal end, a proximal end, and a tip at the distal end. The temperature probe also includes a capacitance sensor disposed on one of the handle and the shaft, the capacitance sensor configured to measure a change in capacitance when positioned proximate a conductor. The temperature probe further includes a temperature sensor disposed on the shaft, the temperature sensor configured to measure a body cavity temperature of a patient.

Abstract: An image processing apparatus including: an image acquisition device for observing a living body; a blood vessel recognition device that irradiates the living body with an exploration laser beam and that recognizes a blood vessel; an arithmetic operation unit that calculates a first laser spot position on a first frame acquired by the image acquisition device when the blood vessel is recognized and that adds a mark corresponding to the first laser spot to a position on a second frame corresponding to the first frame, the second frame being acquired at a time different from the time of the first frame; and a display unit for displaying, on an image acquired by the image acquisition device, a plurality of the marks added by the arithmetic operation unit as a result of the blood vessel being recognized at a plurality of different times.

Abstract: A monitoring system and method for measuring and analyzing physiological signals to assess whether neuromodulation therapy would be successful for a patient. The system includes an external patch device that can be adhered to the chest of the patient in order to measure physiological signals, including heart signals via ECG and respiration via impedance measurement. An acceleration sensor is also provided in order to derive patient posture and activity levels that can be correlated to the measured data.

Abstract: Disclosed are devices, systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various located within the associated chamber of the heart. To create a database of dipole densities, mapping information recorded by multiple electrodes located on one or more catheters and anatomical information is used. In addition, skin electrodes may be implemented. Additionally, one or more ultrasound elements are provided, such as on a clamp assembly or integral to a mapping electrode, to produce real time images of device components and surrounding structures.

Abstract: Disclosed systems and methods relate to determining an intensity level of an exercise using a photoplethysmogram (PPG) sensor. A method of determining an intensity level of an exercise for a user according to one embodiment of the present disclosure includes detecting, by a device, body signals from the user using a PPG sensor. The method includes determining, by the device, a heart rate of the user based on the body signals. The method includes determining, by the device, an error in the heart rate. The method also includes determining, by the device, the intensity level of the exercise for the user based at least on the error.

Abstract: According to one embodiment, an apparatus comprising a portable monitoring device to be affixed to a user. The portable monitoring device including: 1) a set of one or more sensors to generate sensor data indicative of physical activity of a user when the portable monitoring device is affixed to the user; and 2) processing circuitry coupled with the set of sensors, to detect that the user has been sedentary for a period of time, and cause the portable monitoring device to alert the user responsive to the detection to encourage the user to move.

Abstract: A system and method for hemodynamic dysfunction detection may include at least one sensor configured to received one or more signals from a patient, a computing device in data communication with the at least one sensor, a computer-readable storage medium in communication with the computing device, an input device, and an output device. The system may include computer readable instructions to cause the system to receive at least one signal in the time domain from the sensor, determine at least one metric in the frequency domain from the at least one signal in the time domain, and determine the cardiovascular state of the patient from a combination of the at least one metric in the frequency domain and information contained in at least one database of cardiovascular states. The system may also notify a user of a immanent patient cardiovascular event and recommend one or more interventions to mitigate it.

Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

Abstract: A method for operating an x-ray device, (e.g., a fluoroscope), is described herein. The method includes: creating planning information for a therapeutic intervention into a body vessel segment based on a reconstruction of the body vessel segment; providing the planning information to a processing unit of the x-ray device; providing the reconstruction of the body vessel segment to the processing unit; creating a recording of the body vessel segment introduced into a recording region of the x-ray device; registering the reconstruction of the body vessel segment with the body vessel segment in the recording region of the x-ray device; displaying the recording of the body vessel segment on a display device of the x-ray device; and superimposing a graphical representation of the planning information on the recording displayed on the display device, in order to increase the efficiency of the therapeutic intervention into the body vessel segment.

Abstract: An MRI apparatus includes an imaging data acquiring unit and a blood flow information generating unit. The imaging data acquiring unit acquires imaging data from an imaging region including myocardium, without using a contrast medium, by applying a spatial selective excitation pulse to a region including at least a part of an ascending aorta for distinguishably displaying inflowing blood flowing into the imaging region. The blood flow information generating unit generates blood flow image data based on the imaging data.

Abstract: Device for measuring blood pressure hemodynamically in blood vessels at one or more body locations comprising light source; at least three sensors including an array of at least three optical sensors, for receiving light and for obtaining a signal over time comprising temporal per pixel information for at least two wavelengths of light, and corresponding to a flow of blood within a blood vessel over time; a processing unit configured to receive the signal and generate a continuous dynamic blood pressure reading by using the temporal per pixel information for the at least two wavelengths of light to produce heart rate signals from the blood flow, and by applying a modified Windkessel model on the signal such that the blood pressure also depends on a spatial temporal pressure resistance function over time that depends on a body location of the blood flow over time, the pressure resistance function representing elastance/stiffness.

Abstract: Methods, systems, and devices for determining pulseless electrical activity (PEA) are described. The method may include determining by using a first sensor on a person, a heart rate of the person based on sensed electrical activity of the person. A pulse rate of the person may be determined using a second sensor, the pulse rate of the person being based on at least one sensed parameter other than the sensed electrical activity. The method may then include determining a correlation of the determined heart rate and the determined pulse rate and then generating an alert event based at least in part on the correlation being outside of a predetermined threshold.

Abstract: A system and method for a multi-function remote ambulatory cardiac monitoring system. The system includes a housing and a microprocessor disposed within the housing. The microprocessor controls the remote ambulatory cardiac monitoring system. The system also includes an electrode for sensing ECG signals and the electrode being in communication with the microprocessor. An integrated cellular module also is included in the system, and the cellular module is connected to the microprocessor and disposed within the housing. The integrated cellular module transmits ECG signals to a remote center.

Abstract: Systems and methods are provided for monitoring a patient's health is provided. The system includes a monitoring device configured to monitor one or more health parameters of the patient, wherein the monitoring device includes a sensing unit configured to receive the signals pertaining to the one or more health parameters, wherein the sensing unit includes one or more sensors configured to receive signals through non-physical contact with the patient. The system further includes a memory configured to store data pertaining to the signals, and a processor configured to analyze the data using pre-determined information and programmed artificial intelligence.

Abstract: As placement of a physiological monitoring sensor is typically at a sensor site located at an extremity of the body, the state of microcirculation, such as whether vessels are blocked or open, can have a significant effect on the readings at the sensor site. It is therefore desirable to provide a patient monitor and/or physiological monitoring sensor capable of distinguishing the microcirculation state of blood vessels. In some embodiments, the patient monitor and/or sensor provide a warning and/or compensates a measurement based on the microcirculation state. In some embodiments, a microcirculation determination process implementable by the patient monitor and/or sensor is used to determine the state of microcirculation of the patient.

Abstract: The exemplary systems and methods may monitor one or more signals to be used to assess the hemodynamic status of a patient. The one or more signals may be used to calculate, or determine, a plurality of pulse transit times. The plurality of pulse transit times may be used to determine hemodynamic status values that may be indicative of a patient's aggregate hemodynamic status.

Abstract: An MEMS pressure sensing apparatus includes an MEMS pressure sensor, and first and second film sheets. The MEMS pressure sensor has a first space on a side of a pressure detection surface of a diaphragm, and has the diaphragm. The first film sheet is placed on and in contact with a part under measurement so as to support the MEMS pressure sensor, and has a second space communicating with the first space and having a size in a direction parallel to the pressure detection surface. The second film sheet has a third space with a size in a direction parallel to the pressure detection surface for positioning the MEMS pressure sensing apparatus on the part under measurement, and is placed such that an area of the part under measurement is located in the third space before the MEMS pressure sensing apparatus is placed on the part under measurement.

Abstract: A blood pressure estimation apparatus includes: a pulse wave measurement unit measuring a user's pulse wave signal; an electrocardiogram signal measurement unit measuring a user's electrocardiogram signal; and a processing circuit estimating a user's blood pressure value by using the pulse wave and electrocardiogram signals, wherein the processing circuit (a) acquires a pulse wave signal feature by using the pulse wave signal, (b) acquires an electrocardiogram signal feature by using the electrocardiogram signal, (c) acquires a pulse wave propagation time by using the pulse wave and electrocardiogram signals, (d) selects a blood pressure group indicating a relationship between a pulse wave propagation time and blood pressure of the user by using the pulse wave signal feature, electrocardiogram signal feature, and pulse wave propagation time, and (e) estimates the blood pressure value by using the blood pressure group, pulse wave signal feature, electrocardiogram signal feature, and pulse wave propagation time

Abstract: The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract: A pulse wave measuring device includes a processor and a memory. The processor obtains a visible light image, in a visible light wavelength range, of a user irradiated with visible light by a visible light source, obtains an infrared light image, in an infrared light wavelength range, of the user irradiated with infrared light by an infrared light source, extracts a visible light wave indicative of a user's pulse wave from the visible light image, extracts an infrared light wave indicative of a user's pulse wave from the infrared light image, computes a correlation value between the visible and infrared light waves, supplies a control signal for controlling the amount of infrared light emitted from the infrared light source to the infrared light source in accordance with the correlation value, calculates biological information by using at least one of the visible and infrared light waves, and outputs the biological information.

Abstract: A method for determining a heart rate (HR) using an infrared rays (IR) sensor and an electronic device is provided. An image is received using an IR sensor, at least one region of interest (ROI) for measuring the HR is determined in the received image, and the HR is determined based on the at least one determined ROI.

Abstract: A stimulation electrode assembly configured to be positioned relative to a patient for an operative procedure is disclosed. The stimulation electrode may be a connection or self-contained component to contact a portion of a nerve. The stimulation electrode may provide or receive a signal to and/or from the nerve to assist in testing integrity of the nerve.

Abstract: Three-dimensional electrical source imaging of electrical activity in a biological system (e.g., brain or heart) may involve sensor array recording, at multiple locations, of signals (e.g. electrical or magnetic signals) of electrical activity. An initial estimate of an underlying source is obtained. Edge sparsity is imposed on the estimated electrical activity to eliminate background activity and create clear edges between an active source and background activity. The initial estimate is iteratively reweighted and a series of subsequent optimization problems launched to converge to a more accurate estimation of the underlying source. Images depicting a spatial distribution of a source are generated based on the iteratively reweighted edge sparsity, and the time-course of activity for estimated sources generated. Iterative reweighting penalizes locations with smaller source amplitude based on solutions obtained in previous iterations, and continues until a desirable solution is obtained with clear edges.

Abstract: Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.

Abstract: If a job is accepted in the middle of cardiac potential measurement in a state where acquisition of data for stress measurement corresponding to cycles necessary for stress measurement has not been completed, the state of progress of stress measurement is compared with the acceptance timing of the job, and with respect to acceptance of a job for which a time from the acceptance timing of the job to completion of stress measurement on a current measurement object cycle does not exceed a pre-set first setting value, the job is executed after completion of stress measurement in the current measurement cycle, and with respect to acceptance of a job for which a time from the acceptance timing of the job to completion of stress measurement exceeds the first setting value, stress measurement is interrupted and the job is preferentially executed and stress measurement is restarted.

Abstract: Disclosed herein are methods, systems, and devices for identifying increased likelihood of non-ST elevation myocardial infarction (NSTEMI) in a patient based on ECG data. The methods can include determining based on the ECG data that the patient lacks ST elevation (STE) and that the patient exhibits a ventricular repolarization dispersion (VRD) score that exceeds a predetermined threshold value. The VRD score can be based in part on a T wave complexity ratio that serves as a temporal marker of VRD for the patient. Other markers of spatial and time qualities of repolarization can also be included in the VRD score. An elevated VRD score in the absence of STE can indicate a likelihood of NSTEMI in the patient and a potential major adverse cardiac event.