Patents Issued in June 26, 2018
  • Patent number: 10004414
    Abstract: A method for detecting a stimulus pulse by using two or more electrical signals derived from a living body, the method comprising the following steps: (a) for each electrical signal, digitizing the signal with an analog-to-digital converter to produce a sampled signal Sk; (b) for each signal Sk at a sample time ti, computing a primary difference ?kp(ti)=abs[Sk(ti)?Sk(ti?p)]; (c) determining the minimum value of all of the computed differences, such minimum being a detector output D(ti); (d) comparing the detector output D(ti) with a detection threshold; and (e) indicating that a stimulus pulse has been detected when the detector output D(ti) is above the detection threshold.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: June 26, 2018
    Assignee: APN Health, LLC
    Inventor: Donald Brodnick
  • Patent number: 10004415
    Abstract: An extended wear electrocardiography patch is provided. A flexible backing is formed of an elongated strip of stretchable spunlace material. A layer of stretchable adhesive is applied on at least a portion of a contact surface of the flexible backing, which defines a pair of openings on both ends. A non-stretchable circuit is axially affixed to an outward-facing surface of the flexible backing and has a pair of circuit traces. The flexible backing acts as a buffer between the non-stretchable circuit and the stretchable adhesive and prevents disadhesion of the flexible backing during bending. A pair of electrocardiographic electrodes are electrically coupled to each of the circuit traces. Conductive gel is provided in each of the openings and in electrical contact with the pair of electrocardiographic electrodes as the electrodes shift away from the openings in the flexible backing during the bending.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: June 26, 2018
    Assignee: Bardy Diagnostics, Inc.
    Inventors: Jon Mikalson Bishay, Gust H. Bardy, Jason Felix
  • Patent number: 10004416
    Abstract: A catheter adapted or high density mapping and/or ablation of tissue surface has a distal electrode array with offset spine loops, each spine loop having at least a pair of linear portions and a distal portion connecting the pair of linear portions, and one or more electrodes on each linear portion. The linear portions of the plurality of offset spine loops are arranged in-plane a single common plane, and the distal portions of the plurality of offset spine loops are arranged off-plane from the single common plane.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: June 26, 2018
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Steven Wu, Sungwoo Min
  • Patent number: 10004417
    Abstract: A method for attaching a split ring electrode to a catheter tip section includes providing a tubing with a lumen and an opening in the tubing side wall, passing an electrode lead wire through the opening, and wrapping the lead wire around the tubing. A split ring electrode is mounted on the tubing over the wrapped lead wire and opening, with electrically-conductive thermoplastic elastomeric adhesive applied between the ring electrode and the outer surface of the tubing, and reheated to reflow.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: June 26, 2018
    Assignee: Biosense Webster (Israel) Ltd.
    Inventor: Thomas V. Selkee
  • Patent number: 10004418
    Abstract: A method and medical device for identifying a cardiac waveform that includes sensing cardiac signals, determining a plurality of RR-intervals in response to the sensed cardiac signals, determining R-waves associated with the plurality of RR-intervals, determining P-waves in response to the determined R-waves, determining parameters associated with each P-wave, determining relative changes of the P-waves in response to the determined parameters, determining whether each of the P-waves match within a match threshold in response to the determined relative changes, and generating a P-wave template in response to each of the P-waves matching within the match threshold.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: June 26, 2018
    Assignee: Medtronic, Inc.
    Inventors: Jian Cao, Paul J DeGroot
  • Patent number: 10004419
    Abstract: An electrode device for measuring a living body is herein disclosed. The electrode device for measuring a living body signal includes a body comprising a handle part and a tongs part, the body elastically moving by an external force, an electrode part comprising needles disposed on inner surfaces of the tongs part to face each other, and a wire part connected to one end of the electrode part for a connection with a measuring device.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: June 26, 2018
    Assignee: InBody Co., Ltd.
    Inventors: Ki Chul Cha, Chang Su Ji
  • Patent number: 10004420
    Abstract: An apparatus comprises a headset and a control unit in communication with each other. The headset comprises a plurality of electrodes operable to measure ERP readings. The headset is configured to be positioned on a test subject. The control unit is configured to store and administer an ERP test protocol. The control unit is also configured to administer an impedance test and process the impedance of the electrodes. The impedance testing may be performed in an in-band fashion, along the same channels used to perform the ERP testing, at the same frequency of the ERP readings, and substantially simultaneously with the ERP readings.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: June 26, 2018
    Assignee: Neuronetrix Solutions, LLC
    Inventor: Kalford C. Fadem
  • Patent number: 10004421
    Abstract: A disposable, low profile sensor overlay covering for use with biomedical sensors and which includes a framework of flexible component layers supporting an arrangement of electrostatic shielding, insulating, cushioning, and electrically conductive adhesive substrate components configured to form a protective covering encasing the sensor. The combination of component layers provides a means to stabilize the relative position of the sensor with respect to the skin and reduce the potential for sensor dislodgment. The mechanical and electrical configurations act in synergy to shield the sensor from external electrical fields and suppress movement artifact.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: June 26, 2018
    Assignee: Altec, Inc.
    Inventors: L. Donald Gilmore, Carlo J. De Luca
  • Patent number: 10004422
    Abstract: A method for chemical exchange saturation transfer (“CEST”) imaging that is more insensitive to off-resonance and magnetization transfer effects than other CEST methods is provided. Sn general, three different images are obtained: one obtained with radio frequency (“RF”) saturation about a labeling frequency, one obtained with RF saturation about a reference frequency, and one obtained with RF saturation about both the labeling and reference frequencies. This method, termed saturation with frequency alternating radiofrequency irradiation (“SAFARI”), is also very robust to magnetic field inhomogeneities. The three images, referred to as a labeled image, reference image, and dual frequency image, are selectively combined to produce an image of the subject in which CEST contrast is present, but errors arising from off-resonance and magnetization transfer effects are substantially suppressed.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: June 26, 2018
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: David Alsop, Rachel Scheidegger
  • Patent number: 10004423
    Abstract: The embodiments relate to a local coil arrangement for an imaging MRI system, where the system is a head local coil or a head/neck local coil, which includes a mirror housing that is mounted in a rotatable manner on the local coil arrangement.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: June 26, 2018
    Assignee: Siemens Aktiengesellschaft
    Inventor: Daniel Driemel
  • Patent number: 10004424
    Abstract: An endorectal coil (1) includes a tube (40), a spreader (44), and one or more electrically conductive elements (64). The tube (40) is configured for insertion into the rectum (42). The spreader (44) is configured to be positioned at a distal end of the tube (40) and mechanically spread to compress surrounding tissue after the tube (40) is inserted. The one or more electrically conductive elements (64) are tuned to receive magnetic resonance data disposed on at least one of the tube (40), the spreader (44), and adjacent the tube and spreader.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: June 26, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Daniel Wirtz, Peter Mazurkewitz, Christoph Leussler
  • Patent number: 10004425
    Abstract: A method of optimizing scan parameters for LGE-MRI. At least one cardiac MRI TI scout scan is performed by applying an inversion pulse every predetermined heartbeat of a patient. An initial value of an inversion time TIinitial is determined by assessing a set of images generated from the scout scan. A first multiple of a duration between successive indicia of ventricular depolarization is selected, and a relaxation time T1 is determined based on the initial value Tinitial and the first multiple of duration. An optimized inversion time TIoptimal for LGE-MRI is determined based on the relaxation time T1 and a second multiple of a duration between successive indicia of ventricular depolarization. A correction factor is determined based on the optimized inversion time TIoptimal from the initial value of the inversion time TIinitial.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: June 26, 2018
    Assignee: University of Utah Research Foundation
    Inventors: Nassir F. Marrouche, Evgueni G. Kholmovski
  • Patent number: 10004426
    Abstract: In a method for slice positioning of an examination subject in a magnetic resonance system an item of localization information describing the arrangement of the examination subject is automatically determined at least one item of alignment information is automatically determined. At least one slice positioning entry is acquired by an operator, which includes a selection of one of the items of alignment information or an item of manual positioning information. Offset information, which includes a relative slice positioning effected by the manual positioning information, is automatically determined and the slice positioning is determined as a function of the slice positioning entries and the offset information. The offset information is stored separately from the slice positioning in a magnetic resonance measurement protocol, and is used in a further configuration of a further slice positioning.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: June 26, 2018
    Assignee: Siemens Healthcare GmbH
    Inventor: Marcus Wuebbe
  • Patent number: 10004427
    Abstract: Disclosed are methods, systems, and devices for determining a respiration rate. An example method includes capturing by a wearable device over a non-zero time period a PPG signal and making a first determination that, during the non-zero time period, the wearable device has moved less than a threshold amount. Responsive to the first determination, the method includes (i) determining from the PPG signal each of (1) a respiratory-induced intensity variation (RIIV) signal, (2) a respiratory-induced amplitude variation (RIAV) signal, and (3) a respiratory-induced frequency variation (RIFV) signal; and (ii) making a second determination that, based on the RIIV signal, the RIAV signal, and the RIFV signal, a respiration rate is determinable. Responsive to the second determination, the method includes (i) determining the respiration rate and (ii) providing by the wearable device a notification, with the notification being based at least in part on the determined respiration rate.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: June 26, 2018
    Assignee: Verily Life Sciences LLC
    Inventor: Ali Shoeb
  • Patent number: 10004428
    Abstract: A sensor-based quantification and analysis system includes an input device including a plurality of sensors that generate an input based on a force. The input device also includes a transmission device that transmits force information based on the input. The system also includes an output device that receives the force information. A processing unit selects, for each of the plurality of sensors, one of a plurality of levels of a likelihood of tissue damage based on the force and a predetermined time period. Further, the output device includes a display that presents or logs the one of the plurality of levels of the likelihood of tissue damage for each of the plurality of sensors.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: June 26, 2018
    Assignee: Orpyx Medical Technologies, Inc.
    Inventors: Breanne Everett, Marcel Groenland
  • Patent number: 10004429
    Abstract: The present disclosure provides a method for measuring a path length using a handheld electronic device comprising: repeatedly tumbling forward the handheld electronic device so as to cover the path to be measured; sensing a rotational change of the handheld electronic device; counting fractional increments of revolution of the handheld electronic device with respect to a starting position; and estimating the path length based on the counted fractional increments of revolution.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: June 26, 2018
    Assignee: My Size Israel 2014 Ltd.
    Inventor: Oded Shoshan
  • Patent number: 10004430
    Abstract: A fall detection method performed by a fall detection server includes receiving electricity information from a piezoelectric plate disposed adjacent to a bed of a subject, performing a primary determination of whether or not the subject fell from the bed based on the electricity information, and triggering an imaging device to capture an image of a current state of the subject if it is determined that the subject fell, receiving video information including the image of the current state of the subject from the imaging device, and transmitting fall information relating to a fall of the subject to a terminal of the subject, the fall information including one or more of the primary determination result, trigger information of the imaging device, and the video information.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: June 26, 2018
    Assignee: LG CNS CO., LTD.
    Inventor: Jenny Pae
  • Patent number: 10004431
    Abstract: Methods and systems for determining the likelihood that a person is impaired, generally comprising gathering ambient data from sensors operably coupled to a primary measuring device (PMD), analyzing and/or identifying the ambient data, querying at least one database to identify baseline data regarding the person, and comparing the ambient data to the baseline data to determine the likelihood that the person is impaired. The methods and systems advantageously detect medical and/or cognitive impairment without the need for specialized devices, examination by specialists, consent of the person being evaluated, and compliance with recommendations to be examined, and may be applied to estimating the level of impairment of a person due to alcohol, drugs, exposure to toxic chemicals, changes to mental status, insufficient sleep, medical problems, changes to blood sugar levels, divided attention, vision changes, hearing changes, use of a mobile device while walking or operating a vehicle, and other factors.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: June 26, 2018
    Inventors: Gary Stephen Shuster, Brian Mark Shuster, Charles Marion Curry, Jr.
  • Patent number: 10004432
    Abstract: An apparatus, such as a pixel sensor for an ultrasonic imaging apparatus, is disclosed. The apparatus includes a first metallization layer coupled to a piezoelectric layer, wherein a first voltage is formed at the first metallization layer in response to an ultrasonic wave reflecting off an item-to-be-imaged (e.g., a user's fingerprint) and propagating through the piezoelectric layer, and wherein the first metallization layer is situated above a substrate; a second metallization layer situated between the first metallization layer and the substrate; and a device configured to apply a second voltage to the second metallization layer to reduce a parasitic capacitance between the first metallization layer and the substrate.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: June 26, 2018
    Assignee: QUALCOMM Incorporated
    Inventors: Lennart Karl-Axel Mathe, Sameer Wadhwa, Lingli Xia
  • Patent number: 10004433
    Abstract: An electrochemical sensor is disposed on a sensor substrate suitable for flip-chip mounting to another substrate. The electrochemical sensor can be fabricated in bulk by patterning sets of electrodes on a common substrate with vias that electrically couple each electrode to a conductive pad on the opposite side of the substrate. The substrate with electrodes thereon can then be diced and the individual electrochemical sensors can be flip-chip mounted in a body-mountable device in which the sensor can be used to obtain analyte concentrations. As a result, fabrication of the electrochemical sensor electrodes can be isolated from fabrication of the other electronics in the device, which can facilitate efficient fabrication of the sensor and allows for other electronics to be fabricated without restrictions associated with the electrode fabrication.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: June 26, 2018
    Assignee: Verily Life Sciences LLC
    Inventor: James Etzkorn
  • Patent number: 10004434
    Abstract: A sensing device, designed to be used in contact with the skin, contains a plurality of individually controllable sites for electrochemically monitoring an analyte, such as glucose, in interstitial fluid of a user. The device includes at least a hydrophobic layer designed to contact the skin; a capillary channel providing an opening adjacent the skin; a metal electrode layer having a sensor layer applied to an edge portion thereof such that it is exposed to the interior of said capillary channel, the sensing layer being effective to measure the analyte.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 26, 2018
    Assignee: Georgetown University
    Inventor: Makarand Paranjape
  • Patent number: 10004435
    Abstract: “Zero-click” viewing of sensor data without any user input is provided. A display with sensor data may be “always on,” and may enable discrete viewing of sensor data without significant user hassle. Also, a system may be configured to display only current data, and/or to display the most current data for only a set interval. Also, one device in a continuous analyte monitoring system may be designated as a primary device, or hub, for receiving sensor data, and may control the flow of information and/or alerts to other devices in the system. Sensor data and/or alerts may be sent to a hierarchy of devices and/or persons in a designated order.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: June 26, 2018
    Assignee: DexCom, Inc.
    Inventors: Shawn Larvenz, Katherine Yerre Koehler, Apurv Ullas Kamath, Rian Draeger, Subrai G. Pai
  • Patent number: 10004436
    Abstract: “Zero-click” viewing of sensor data without any user input is provided. A display with sensor data may be “always on,” and may enable discrete viewing of sensor data without significant user hassle. Also, a system may be configured to display only current data, and/or to display the most current data for only a set interval. Also, one device in a continuous analyte monitoring system may be designated as a primary device, or hub, for receiving sensor data, and may control the flow of information and/or alerts to other devices in the system. Sensor data and/or alerts may be sent to a hierarchy of devices and/or persons in a designated order.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: June 26, 2018
    Assignee: DexCom, Inc.
    Inventors: Shawn Larvenz, Katherine Yerre Koehler, Apurv Ullas Kamath, Rian Draeger, Subrai G. Pai
  • Patent number: 10004437
    Abstract: The present embodiments provide systems and methods for, among others, tracking sensor insertion locations in a continuous analyte monitoring system. Data gathered from sensor sessions can be used in different ways, such as providing a user with a suggested rotation of insertion locations, correlating data from a given sensor session with sensor accuracy and/or sensor session length, and providing a user with a suggested next insertion location based upon past sensor accuracy and/or sensor session length at that location.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: June 26, 2018
    Assignee: DexCom, Inc.
    Inventors: Katherine Yerre Koehler, Leif N. Bowman, Rian Draeger, Laura Dunn, Eli Reihman
  • Patent number: 10004438
    Abstract: A first embodiment of the implantable real-time oximeter of the present invention is attached around a blood vessel near the site of a likely stroke to monitor large and medium size cerebral arteries. Another embodiment of the implantable real-time oximeter can be passed within cerebral blood vessels to monitor the oxygenation status of the surrounding cerebral tissues. When used within cerebral blood vessels, the emitter and detector are coplanar and contained in a small area, for example, 50-120 ?m.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 26, 2018
    Assignee: University of Rochester
    Inventors: Jason Haitao Huang, Samantha Dayawansa
  • Patent number: 10004439
    Abstract: Ceria nanoparticle compositions for use as electrode materials for in vivo electrochemical analyte sensors (e.g., glucose sensors) are provided, for example to form a cathode or a reference electrode. The ceria nanoparticle compositions may be combined with a conductive material (e.g., mixed with) to form the cathode or the reference electrode, or the ceria nanoparticle compositions may be deposited over conductive material to form the cathode or the reference electrode. Electrochemical in vivo sensors for monitoring the concentration of an analyte having a reference electrode and/or a cathode that includes a ceria nanoparticle composition, and methods for monitoring an analyte concentration using the electrochemical sensors are also described. Methods of making in vivo electrochemical analyte sensors having a reference electrode and/or a cathode that includes a ceria nanoparticle composition are also provided.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: June 26, 2018
    Assignee: Abbott Diabetes Care Inc.
    Inventor: Adam Heller
  • Patent number: 10004440
    Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: June 26, 2018
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Robert Graham Cooks, Zheng Ouyang, Chien-Hsun Chen, Ziqing Lin, Livia Schiavinato Eberlin
  • Patent number: 10004441
    Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: June 26, 2018
    Assignee: ABBOTT DIABETES CARE INC.
    Inventors: Benjamin J. Feldman, Zenghe Liu, Tianmei Ouyang
  • Patent number: 10004442
    Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: June 26, 2018
    Assignee: DexCom, Inc.
    Inventors: Sebastian Böhm, Daiting Rong, Peter C. Simpson
  • Patent number: 10004443
    Abstract: A protecting mechanism for a blood sampling device contains: a trigger unit and a switching assembly. The trigger unit includes a lancet holder, a triggering shaft, and a resilient element. The lancet holder has a launching portion, a first outer protrusion, a through orifice, and a first inner shoulder, wherein a bottom end of the triggering shaft moves in the through hole, and the triggering shaft has a first outer shoulder for engaging with the first inner shoulder of lancet holder, the resilient element is fitted with the triggering shaft and abuts against the lancet holder by ways of its bottom end. The switching assembly includes a fixing jacket having an abutting portion, a rotating tube having a first inner protrusion and two opposite second inner protrusions, and a driving sheath having two stopping sets, wherein each stopping set has two second outer protrusions.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: June 26, 2018
    Assignee: MEDIFUN CORPORATION
    Inventor: Shao-Lun Hsiao
  • Patent number: 10004444
    Abstract: The application relates to a collection assembly (1), in particular for blood samples, comprising a sample container (2) and a closure device (3) which has a closure cap (22) and a pierceable septum (26) held on the closure cap. At its open end (4) delimited by an end face (11), the sample container has a flange (13) and an annular skirt (15), the flange projecting radially beyond a side wall (7). The annular skirt (15) extends axially from a flange end (14) to a closed end (5) of the sample container (2). The sample container (2), the flange (13) and the annular skirt form a one-piece component. Between an outer surface (9) of the side wall (7) and an inner annular skirt surface (16) facing toward this outer surface, there is an approximately tubular free space (17) which is delimited in the axial direction in the region of the open end (4) by the flange (13).
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: June 26, 2018
    Assignee: Greiner Bio-One GmbH
    Inventors: Christian Bauer, Georg Kofler
  • Patent number: 10004445
    Abstract: The invention relates to apparatus and methods for stimulating living tissues to determine nerve conduction properties using a pair of stimulator probes and a plurality of detection electrodes. The invention overcomes the problem of reporting potentially inaccurate nerve conduction results by detecting a stimulator probe short or shunt condition during nerve conduction tests. Detection of a short or shunt condition between two stimulator probes is accomplished by monitoring the magnitude of the stimulus artifact waveform acquired from the detection electrodes and the voltage difference between the stimulator probes. A test is flagged when magnitude of the stimulus artifact waveform is below a first threshold and voltage difference between the two stimulator probes is below a second threshold. The first and second threshold values are determined based on the known spatial relationship between the stimulator probes and detection electrodes. Feedback is provided to the tester to alert defective test conditions.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: June 26, 2018
    Assignee: NeuroMetrix, Inc.
    Inventors: Bonniejean Boettcher, Glenn Herb, Xuan Kong
  • Patent number: 10004446
    Abstract: We report a method for detecting epileptic or non-epileptic seizures, comprising: receiving a heart rate of a patient; calculating a percentage change of the heart rate in reference to at least one of the patient's maximal heart rate, reserve heart rate, or a resting heart rate; detecting an epileptic seizure if the percentage increase in the heart rate reaches a threshold value; and taking at least one responsive action selected from issuing a warning, delivering a therapy, determining a seizure severity, or logging at least one of a date and time of occurrence of the seizure, its severity, the type of therapy, or its effect, in response to the detection. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: June 26, 2018
    Inventor: Ivan Osorio
  • Patent number: 10004447
    Abstract: A system for determining the location of patients uses a patient-associated communicator which wirelessly communicates with a network of environmental reference communicators arranged at fixed or otherwise known locations. A camera can be used to monitor or detect pressure ulcers and relay the information to a host system. Other embodiments are also disclosed.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: June 26, 2018
    Assignee: LEAF HEALTHCARE, INC.
    Inventors: Daniel Z. Shen, Barrett J. Larson, Mark V. Weckwerth
  • Patent number: 10004448
    Abstract: Provided is an apparatus for measuring the thickness, roughness, and morphology index of the mandibular cortical bone using a dental panorama image to assist in the diagnosis of osteoporosis, wherein the thickness, roughness, and morphological index of the cortical bone is measured more accurately and the diagnosis of osteoporosis can be supported more accurately. An osteoporosis diagnostic support apparatus, wherein the apparatus has a contour extraction unit adapted to extract a mandibular contour from an image of a mandibular cortical bone photographed by a photographic apparatus adapted to photograph the mandibular cortical bone and surroundings thereof, a line segment extraction unit adapted to extract line segments from the image of the mandibular cortical bone photographed by the photographic apparatus; and a cortical bone thickness calculation unit adapted to calculate a thickness of the cortical bone based on the extracted mandibular contour and line segments.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: June 26, 2018
    Assignee: Media Co., Ltd.
    Inventors: Hironobu Tsuji, Yosuke Tsuji, Tatsuro Hayashi, Hiroshi Fujita, Takeshi Hara, Chisako Muramatsu, Kazuki Horiba, Akitoshi Katsumata
  • Patent number: 10004449
    Abstract: A measurement device suitable to measure a load applied by the muscular-skeletal system is disclosed. The measurement device can be a prosthetic component having an articular surface for measuring parameters of a joint in extension or flexion. A first and second support structure forms an enclosure having load-bearing surfaces. The first support structure includes at least one alignment feature extending from a surface. The second support structure includes a corresponding opening for receiving the alignment feature. The first and second support structures include a peripheral channel and corresponding flange to support sealing of the enclosure. Interior to the enclosure is the measurement system. The alignment feature couples through and aligns a first load plate, a sensor array, and a second load plate to surfaces of the first and second support structures. The sensor array is coupled to electronic circuitry in the enclosure via a unitary circuit board.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: June 26, 2018
    Assignee: Orthosensor Inc.
    Inventors: Marc Stein, Gabriel Carrasco
  • Patent number: 10004450
    Abstract: Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: June 26, 2018
    Assignee: TEXAS MEDICAL CENTER
    Inventors: Nicole C. Moskowitz, Jessica Traver, Xavier Garcia-Rojas, Yashar Ganjeh
  • Patent number: 10004451
    Abstract: A user monitoring device system includes a user monitoring device with one or more microphones, a transmitter and sensors to determine light, sound temperature and humidity near the user, the transmitter serving as a communication system. A motion detection apparatus detects a user's movement information. The motion detection apparatus and the monitoring system assist to determine at least one of: user sleep information and sleep behavior information, or user respiration information. A cloud based system is in communication with the monitoring device and the motion detection apparatus. The cloud based system includes a user database.
    Type: Grant
    Filed: September 27, 2016
    Date of Patent: June 26, 2018
    Assignee: FITBIT, INC.
    Inventor: James Proud
  • Patent number: 10004452
    Abstract: A system and methods for screening patients suspected of obstructive sleep apnea. The system includes a sound detection device configured for detecting tracheal respiratory sound signals of a patient and a Sao2 detection device for detecting SaO2 signals of the patient. The system also has a head position detection device for detecting the head positions of the patient during testing, and a processing module for receiving and analyzing the tracheal respiratory sound signals to extract sound data and the Sao2 signals to extract blood oxygen saturation data. The processing module further receives and analyzes the head position signals captured by the head position detection device to generate head position data. The system may further include a display for displaying information about the various data generated by the processing module.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: June 26, 2018
    Assignee: University of Manitoba
    Inventors: Zahra Kazem-Moussavi, Azadeh Yadollahi
  • Patent number: 10004453
    Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: June 26, 2018
    Assignee: Korea Institute of Science and Technology
    Inventors: Il-Joo Cho, Eui Sung Yoon, Hyogeun Shin, Uikyu Chae, Hyunjoo Jenny Lee
  • Patent number: 10004454
    Abstract: The present invention is related to a breath pacing device (10) for pacing the respiratory activity of a subject, comprising an output unit (12) for outputting a sequence of output signals, a control unit (16) provided to control the output unit, and an input unit (14) connected to or integrated into the output unit for generating an input signal related to a respiration characteristic of a subject. The control unit is provided to control the length of the sequence at least based on characteristics of the input signal. The invention is further related to a corresponding method for pacing the respiratory activity of a subject.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: June 26, 2018
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jan Krans, Bartel Van De Sluis, Juergen Vogt, Ronaldus Aarts, Tim Tijs, Bernardo Arnoldus Mulder, Paulus Dillen, Georgo Zorz Angelis, Roy Raymann, Petronella Zwartkruis-Pelgrim, Jia Du, Ype Brada, Maarten Van Den Boogaard
  • Patent number: 10004455
    Abstract: A real time visualization method and system for evaluating and monitoring recovery progress of Anterior Cruciate Ligament reconstructed/injured subject is provided. The method includes receiving multiple super-imposed bio-signals from an electromyogram (EMG) for muscles of limbs of the patient and signals pertaining to three dimensional kinematics measurement from a motion sensor set, processing the signals to extract wavelet features and evaluating the wavelet features to determine the extent of rehabilitation and a recovery classification of the patient's limb from ACL injury. The system includes an input interface circuit, a processing module, a comparator module and an output interface circuit for providing an estimate of the extent of rehabilitation the patient's limb from ACL injury.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: June 26, 2018
    Assignee: UNIVERSITI BRUNEI DARUSSALAM
    Inventors: S. M. N Arosha Senanayake, Owais Ahmed Malik
  • Patent number: 10004456
    Abstract: The invention provides an intelligent dental ornament and a method of using the same, the intelligent dental ornament comprising: a dental ornament body with a cavity, a tester located within the cavity and for detecting a physiological parameter, a battery used by the tester, and a trigger switch for triggering the tester to start test; the dental ornament body is further provided with a through-hole for at least one pipette of the tester stretching out of the dental ornament body, and a sealing cover for sealing the through-hole. When the trigger switch activates the tester, the sealing cover is opened, and the pipette of the tester stretches out of the dental ornament body through the through-hole to obtain the saliva of the subject, and the physiology parameter in the saliva is detected, and the detection result is sent to an external device in communication with the tester.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: June 26, 2018
    Assignees: BOE TECHNOLOGY GROUP CO., LTD., BOE OPTICAL SCIENCE AND TECHNOLOGY CO., LTD.
    Inventor: Zongmei Mu
  • Patent number: 10004457
    Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: June 26, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: James Etzkorn, Babak Amirparviz
  • Patent number: 10004458
    Abstract: Systems and methods for controlled sympathectomy procedures for neuromodulation are disclosed. A system for controlled micro ablation procedures is disclosed. A guidewire including one or more sensors or electrodes for accessing and recording physiologic information from one or more anatomical sites within the parenchyma of an organ as part of a physiologic monitoring session, a diagnostic test, or a neuromodulation procedure is disclosed. A guidewire including one or more sensors and/or a means for energy delivery, for performing a neuromodulation procedure within a small vessel within a body is disclosed.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: June 26, 2018
    Assignee: AUTONOMIX MEDICAL, INC.
    Inventors: Landy Toth, Robert Schwartz
  • Patent number: 10004459
    Abstract: The present invention includes systems, devices and methods for treating and/or diagnosing a heart arrhythmia, such as atrial fibrillation. Specifically, the present invention provides a system including a diagnostic catheter and an ablation catheter. The diagnostic catheter includes a shaft, multiple dipole mapping electrodes and multiple ultrasound transducers. The ablation catheter is slidingly received by the diagnostic catheter shaft.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: June 26, 2018
    Assignee: ACUTUS MEDICAL, INC.
    Inventors: Randell L. Werneth, Graydon E. Beatty, Timothy J. Corvi, J. Christopher Flaherty, Marcus Frederick Julian
  • Patent number: 10004460
    Abstract: A stand-on physiological sensor (e.g. floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ECG waveforms. The sensor is similar in configuration to a common bathroom scale and includes electrodes that take electrical measurements from a patient's feet to generate bioimpedance waveforms, which are analyzed digitally to extract various other parameters, as well as a cuff-type blood pressure system that takes physical blood pressure measurements at one of the patient's feet. Blood pressure can also be calculated/derived from the bioimpedance waveforms. Measured parameters are transmitted wirelessly to facilitate remote monitoring of the patient for heart failure, chronic heart failure, end-stage renal disease, cardiac arrhythmias, and other degenerative diseases.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: June 26, 2018
    Assignee: TOSENSE, INC.
    Inventors: Matthew Banet, Marshal Singh Dhillon, Susan Meeks Pede, Lauren Nicole Miller Hayward, Arthur Deptala, Jonas Dean Cochran
  • Patent number: 10004461
    Abstract: A physiological signal processing method for filtering noise generated by a physiological signal processing system is performed by a physiological signal processing system having a sensing device and a filtering device in connection with the sensing device. The method comprises steps of synchronously receiving a physiological signal and a vibrational signal detected by the sensing device, performing a noise determination algorithm to acquire information in multiple time periods with noises occurring in corresponding time periods according to the vibrational signal, performing a physiological signal filtering algorithm to filter the noises in corresponding time periods of the physiological signal and compensate the filtered physiological signal, and estimating a physiological parameter according to a result of the signal compensation to generate the physiological parameter with accuracy.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: June 26, 2018
    Assignee: AUTOMOTIVE RESEARCH & TESTING CENTER
    Inventors: Hsuan-Yu Huang, Yen-Cheng Feng
  • Patent number: 10004462
    Abstract: The disclosure herein provides methods, systems, and devices for removing prospective motion correction from medical imaging scans.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: June 26, 2018
    Assignees: KinetiCor, Inc., The University of Hawai'i, The Queen's Medical Center
    Inventors: Thomas Michael Ernst, Benjamin Anton Zahneisen, Jeffrey N. Yu
  • Patent number: 10004463
    Abstract: Systems, methods, and computer-readable media are disclosed for identifying when a subject is likely to be affected by a medical condition. For example, at least one processor may be configured to receive information reflective of an external soft tissue image of the subject. The processor may also be configured to perform an evaluation of the external soft tissue image information and to generate evaluation result information based, at least in part, on the evaluation. The processor may also be configured to predict a likelihood that the subject is affected by the medical condition based, at least in part, on the evaluation result information.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: June 26, 2018
    Assignee: FDNA INC.
    Inventors: Dekel Gelbman, Yaron Gurovich