Abstract: A sample manipulator includes a drive system, a pair of flexure plates, and piezoelectric actuators. The drive system preferably includes a pair of drive pulleys on opposite sides of a driven pulley and coupled to the driven pulley by a drive belt. The sample rotates around a rotational axis with the driven pulley. The driven pulley is preferably driven by a pair of drive belts, one being located above the sample, and the other being located below the sample. Fluid bearings provide improved rotation of the driven pulley. The flexure plates are preferably monolithic with a high number of machined flex veins with the side of a tapered threaded screw being used to create the high force required to bend many flexures at the same time for sample motion and to provide fine, precise sub-micron motion control. The piezoelectric actuators provide high-precision control of the load on the sample.

Abstract: A system and method involve applying an electron beam to a sample and obtaining an image of the sample with the applied electron beam. An orientation of the sample relative to the sample's zone axis is automatically determined based on a distribution of reflections in the image. The orientation of the sample is automatically adjusted to align with the sample's zone axis based on the determined orientation.

Abstract: In situ measuring devices, methods of making the same, and methods of using the same are provided herein. The in situ measuring devices can include a capillary tube having a reference material sealed inside the capillary tube, where the capillary tube is positioned inside of a solid state or MAS NMR rotor. A target sample can also be positioned in the interior of the solid state or MAS NMR rotor but is sequestered from the reference material by a capillary tube wall. The in situ measuring devices can be used in solid state MAS NMR spectroscopy to quantify one or more parameters of a target sample, such as the quantity of a sample, chemical identity of a sample, or temperature of a sample.

Abstract: A nanostructure device is provided and performs dual functions as a nano-switching/sensing device. The nanostructure device includes a doped semiconducting substrate, an insulating layer disposed on the doped semiconducting substrate, an electrode formed on the insulating layer, and at least one polymer nanofiber deposited on the electrode. The at least one polymer nanofiber provides an electrical connection between the electrode and the substrate and is the electroactive element in the device.

Abstract: Apparatus for determining and/or monitoring at least one limit value of a process variable of a medium in a container, comprising at least one sensor unit for registering a measured value dependent on the process variable and at least one electronics unit for producing a measurement signal dependent on the process variable. The invention is distinguished by features including that the apparatus is embodied to draw energy via a voltage output and a digital input of a recorder apparatus or a process control system.

Abstract: A biosensor (102) for determining the presence or amount of a substance in a sample and methods of use of the biosensor (102) are provided. The biosensor (102) for receiving a user sample to be analyzed includes a mixture for electrochemical reaction with an analyte. The mixture includes an enzyme, a mediator and an oxidizable species as an internal reference.

Abstract: This invention relates to an apparatus suitable to be used for analyzing at least one sample with an electrochemical sensor array, comprising at least one upper layer; at least one inlet and at least one outlet opening provided on the upper layer; at least one lower layer having at least one recess thereon; at least one two-sided adhesive membrane matching to the recess; at least one sensor array secured to the lower layer, at least one reference electrode, at least one counter electrode, at least one communication channel, at least one conductive line providing a connection between the working electrode and the communication channel on at least one plate; at least one further two-sided adhesive membrane spaced from the adhesive membrane positioned on the lower layer and enabling the sensor array to be secured to the upper layer.

Abstract: A device, apparatus and method for trapping metal ions and detecting metal ion contamination in a solution provide a semiconductor device formed on a semiconductor substrate and including an N-well formed over a P-type substrate and at least a contact portion of the N-well in electrical contact with the solution. When the semiconductor device is optically illuminated, a P/N junction is formed as a result of photovoltaic phenomena. Metal ions from the solution migrate to the contact area due to the voltage created at the P/N junction. The semiconductor device includes a conductive structure with conductive features separated by a gap and therefore in an initially electrically open state. When the ions migrate to the contact area, they precipitate, at least partially bridging the gap and creating conductance through the conductive structure. The conductance may be measured to determine the amount of metal ion contamination.

Abstract: Ion sensor based on differential measurement comprising an ISFTET-REFET pair wherein the REFET is defined by a structure composed of an ISFET covered by a microreservoir where an internal reference solution is contained. The sensor comprises a first and a second ion-selective field effect transistor, an electrode, a substrate on the surface whereof are integrated the two transistors, connection tracks and the electrode and a structure adhered on the first ion-selective field effect transistor which creates a microreservoir on the gate of said first transistor, with the microreservoir having a microchannel which connects the microreservoir with the exterior and the microreservoir being filled with the reference solution.

Abstract: A method recalibrates in situ a comparison electrode integrated into an electrochemical system. The electrochemical system includes a working electrode, a counter electrode, and an electrolyte. The method includes verifying a potential of the comparison electrode relative to the working electrode or to the counter electrode in situ, detecting whether there is a drift in the potential of the comparison electrode relative to a potential plateau for which the comparison electrode was functionalized or designed, and when the drift is detected, recalibrating the comparison electrode in situ.

Abstract: A biomolecule analyzer (100) includes an arm part (20-23, 66) retaining a transfer membrane (1) that is arranged at a position opposing a first opening (50a), and a drive unit (62-65) that is provided below an anode buffer tank (30), and drives the arm part in a substantially horizontal direction, in which the arm part passes along outer sides of side walls of the anode buffer tank (30), wraps around upper ends of the side walls and links at inner walls of the side wall.

Abstract: Gradient elution isotachophoretic apparatus, and systems for performing gradient elution isotachophoresis to separate, purify, concentrate, quantify, and/or extract charged analytes from a sample. The isotachophoretic apparatus include an electrophoretic assembly, a sampling assembly connected to the electrophoretic assembly, and/or a support structure connected to the electrophoretic assembly and/or to the sampling assembly. The system includes an isotachophoretic apparatus, and a controller communicatively coupled to the isotachophoretic apparatus. The controller includes a storage medium and a processor for executing computer readable and executable instructions.

Abstract: The present invention is related to a free-flow electrophoresis method for separating at least one analyte of interest from a mixture of analytes, wherein the method uses a separation medium comprising two or more individual separation media, wherein the two or more individual separation media differ in their pH value, and wherein each of the two or more individual separation media comprise at least one anion of at least one acid and at least one cation of at least one base, wherein the at least one acid is the same in each of the two or more individual separation media and the at least one base is the same in each of the two or more individual separation media.

Abstract: A system and method using magnetic sensing to non-intrusively and non-destructively characterize ferromagnetic material within infrastructure. The system includes sensors for measuring magnetic field gradients from a standoff distance adjacent to ferromagnetic material. The method includes using the system to measure magnetic fields, determining magnetic field gradients measured by a sensor array, and comparing measured and modeled or historical magnetic field gradients at the same or similar positions to identify differences caused by a phenomenon in the ferromagnetic material, and, in a particular embodiment, to recognize defects and developing defects.

Abstract: Provided herein are methods and devices for determining water and sediment content in a hydrocarbon fluid sample. The methods and devices for determining water and sediment content in a hydrocarbon fluid sample include a Karl Fischer titration device and a titration vessel configured to implement a Karl Fischer titration and an ultrasonic particle detector configured to identify sediment in the hydrocarbon fluid sample.

Abstract: A noisemaker system includes a node of an infrastructure system; and a noisemaker connected in fluid communication with the node, the noisemaker including a noisemaker housing defining a noisemaker cavity, and a pulsing device positioned within the noisemaker cavity, the pulsing device configured to contact a fluid within the noisemaker cavity and generate an acoustic signal within the fluid.

Abstract: A system processes data signals consisting of sums of independent signal terms in order to generate one or more of those terms. The generated terms are computed using a set of reference signals to construct alternative support sets, whose images are computed on the data signals. Computed images that are independent of the residue of the data signal minus the image are identified as independent signal terms, as are the residues. These initial signal terms are used to compute additional terms. Identified terms from different data signals are organized into independent slices, and slices whose terms are supported by sets of reference signals are associated with those supporting sets.

Abstract: A part (120) may be subjected to both a resonance inspection and a surface vibration inspection. Various protocols (230; 240; 250; 280; 260) are disclosed as to how the results of one or more of these inspections may be used to evaluate the part (120).

Abstract: A device for detecting a structure-borne sound signal, in particular for detecting a structure-borne sound signal caused by an event of damage on a component to be monitored, having at least one structure-borne sound sensor, at least one signal-conducting connection of the structure-borne sound sensor to an evaluation device, and a protective body. The structure-borne sound sensor has a structure-borne sound-conducting connection to the protective body and the protective body has a structure-borne sound-conducting connection to the component to be monitored.

Abstract: The provided apparatus for automated nondestructive inspection of a metal structure having a surface comprises an ultrasonic nondestructive inspection unit, a nondestructive inspection unit based on magnetic flux leakage method, an eddy-current nondestructive inspection unit, a control unit connected to the ultrasonic nondestructive inspection unit, the nondestructive inspection unit based on the magnetic flux leakage method and the eddy-current nondestructive inspection unit for sending control signals to carry out inspection of the metal structure, and a navigation unit connected to the control unit, wherein the navigation unit determines a position of said apparatus relative to the metal structure, determines a state of the surface of the metal structure and sends signals into the control unit. The nondestructive inspection unit based on magnetic flux leakage method changes a magnetic field induction generated by this unit from a minimum value close to zero value to a predetermined maximum value.

Abstract: The invention relates to a method for testing a workpiece using ultrasound, wherein an ultrasonic probe generates an ultrasound signal which has a central beam and which is coupled into the workpiece under test, and the central beam is guided along a predefined path on the surface of the workpiece, the central beam and the workpiece being moved in opposite directions at least along a portion of the path.

Abstract: An ultrasonic flaw detection jig includes a base section with which a probe of the ultrasonic inspection apparatus is brought into contact; and a prominence section provided for the base section and inserted into an inspection object hole of an inspection object. The inspection object hole includes a countersunk section connected with a main surface of the inspection object and extending from the main surface while reducing a diameter; and a connection section connecting a bottom of the countersunk section and the rear surface of the inspection object. The prominence section has a conical shape corresponding to the shape of the countersunk section.

Abstract: An ultrasonic sensor has: a diaphragm that includes at least two partial regions for emitting and/or receiving ultrasonic signals, the two partial regions possessing different resonance characteristics; and at least one electromechanical transducer coupled to the diaphragm, to which transducer a control signal having at least two different control signal frequencies is applied. In this context, a first control signal frequency is in the range of a resonant frequency of a first partial region of the diaphragm, and a second control signal frequency is in the range of a resonant frequency of a second partial region of the diaphragm. Alternatively, two electromechanical transducers are used, which are coupled to a diaphragm and have different resonance characteristics.

Abstract: A system for concentrating an analyte gas in a gas stream of an analytical system is provided. The system comprises at least one separation device, at least one gas inlet line, at least one detector, at least one gas outlet line, a first split line in connected to the gas inlet line, and a first split valve for controlling gas flow in the first split line. Also provided is a method for concentrating an analyte gas.

Abstract: A gas chromatography (GC) column heating apparatus is described. The GC column heating apparatus includes a first substrate; a heating element disposed over the first substrate; and a second substrate. A gas chromatography (GC) column heating and cooling apparatus is also described. The GC column cooling and heating apparatus includes a housing configured to receive a heating apparatus, the heating apparatus comprising a first side and a second side; a first thermal insulation layer disposed over the first side; a second thermal insulation layer disposed over the second side; and an actuator connected to the housing and configured to move the first and second thermal insulation layers in contact with the first and second sides, respectively, during a heating sequence, and to move the first and second layers of insulation out of contact with the first and second sides, respectively, during a cooling sequence.

Abstract: A plug unit for connecting capillary tubes includes a plug housing that has an axial borehole, a plug capillary tube that projects through the axial borehole, and a sealing element that surrounds the plug capillary tube. The front end of the plug capillary tube is sealed by an elastic and/or plastic deformation of the sealing element against the capillary tube receptacle opening of a bushing unit. A hollow cylindrical pressure piece is provided that surrounds the sealing element in an axial region facing away from the end surface of the plug capillary tube, and the pressure piece has a rearward end side that faces away from the end surface of the plug capillary tube and that can be loaded by the plug housing with an axial pressure force when the plug unit and bushing unit are connected.

Abstract: Disclosed herein are compounds and methods for identifying and quantifying a metabolite or breakdown product of PEG. A sample may be assayed for PEG metabolites or breakdown products using liquid chromatography combined with mass spectrometry. Derivatization of the PEG metabolites or breakdown products within the sample with pentaflurobenzoyl chloride in conjunction with negative chemical ionization mode liquid chromatography optimizes the assay.

Abstract: The present invention relates to a hydrogel bead for detecting hydrofluoric acid and a kit comprising the same, and more particularly, to a hydrogel bead capable of detecting hydrofluoric acid using an organometallic ligand compound that reversibly changes color depending on the concentration of hydrofluoric acid when coming into contact with hydrofluoric acid, and to a kit for detecting hydrofluoric acid comprising the same. In an embodiment, a method for preparing a hydrogel bead for detecting hydrofluoric acid comprises the steps of: mixing an organic compound, which contains an aromatic functional group having at least one hydroxyl group bonded thereto, with a solution of a metal-ligand compound that bonds with the organic compound, thereby preparing a mixed solution; dropping the mixed solution onto a gelling agent; and adding coagulating agent to the mixture resulting from the dropping step to form a porous bead.

Abstract: A method for operating a measuring site (1), wherein a measured variable is determined by a sensor (5) that can be calibrated and in which an exact as possible planning of activities, to which, for example, calibration or sensor replacement belong, is possible is obtained, in accordance with the method, in that the sensor (5) is calibrated at presettable calibration points in time, that at least one parameter in conjunction with calibration is stored as a part of reference data of the sensor (5) and that at least one aging-dependent variable of a sensor (8, 6) differing from the sensor (5) is estimated based on reference data of the sensor (5).

Abstract: A sensor includes a detector element, a connection terminal, and a separator. The contacting portion is in contact with a conductive member so as to overlap the conductive member in a thickness direction, which is a direction of thickness of the detector element between the principal surfaces. The separator includes an element accommodation space that accommodates a portion of an element contact portion and an element back portion, and a partition wall that separates the element accommodation space from a terminal accommodation space that accommodates the contacting portion and a portion of the conductive member and that is adjacent to the element accommodation space in the thickness direction. A frame main body is disposed in an element-side region, which is a region on an element-accommodation-space side in the thickness direction in a region obtained by extending the terminal accommodation space toward the front side in the axial direction.

Abstract: A metal oxide heterostructure includes mixing a first precursor and a second precursor to form a precursor aqueous mixture, adding at least one constituent to the precursor aqueous mixture to form a first solution, adding a nanostructuring reagent to the first solution to form a second solution, sonochemically treating the second solution to provide a metal oxide powder, filtering, washing, and drying the metal oxide powder to provide a metal oxide nanocomposite heterostructure for a sensing layer of a hydrogen sulfide sensor. A method for forming a hydrogen sulfide sensor includes the metal oxide heterostructure, forming a sensing material, contacting the sensing material with interdigitated electrodes to form a sensing layer, and thermally consolidating the sensing layer to form the hydrogen sulfide sensor.

Abstract: A device for measuring the concentrations of volatile organic compounds (VOCs) in air. The device includes a sample chamber for accepting a sample of air; at least one ionization source for ionizing VOCs in the sample; an ionic liquid trap containing an ionic liquid that captures the ionized VOCs; a circuit for generating a electric current through the device to run the ionization and capture of the ionized VOCs; and a chemical sensor for detecting and measuring concentrations of the VOCs in the sample of air. The device, which may be hand-held, portable, or designed to sit on a bench top, may be used on any animal, including humans.

Abstract: One variation of a method for tracking temperature exposure of foodstuffs within an automated sandwich assembly apparatus includes: at a topping module, receiving first topping sample and a second topping sample in a column of topping samples; at a first time, determining a first temperature of the first topping sample; in response to the first temperature of the first topping sample exceeding a threshold temperature, setting a first timer assigned to the first topping sample; cutting a slice from the second topping sample; following dispensation of the slice of the second topping sample from the topping module, tracking a position of the first topping sample within the topping module; and in response to expiration of the first timer prior to dispensation of a final portion of the first topping sample from the topping module, disqualifying the final portion of the first topping sample from dispensation onto a topping vehicle.

Abstract: The present invention provides an adulterated peanut oil detector and an adulterated peanut oil detection method, and pertains to the technical domain of product analysis. The detector comprises a casing, a LCD and Return key, Enter key, Up key, Down key, a power switch, a power socket, and a USB interface arranged on the casing, and a microprocessor and a power supply unit mounted in the casing and electrically connected to the components on the casing, wherein, a module cover is arranged on the top surface of the casing, and a pretreatment module and a detection module are mounted in the space under the module cover. The pretreatment module comprises a heating body and cuvette slots, and the detection module comprises an axial fan, a radiating plate, a refrigerating plate, and cuvette slots. The detection method comprises sample preheating procedure and slow refrigeration procedure.

Abstract: A high-resolution in situ sensing system and method for providing continuous measurements of at least one dissolved gas including a sample liquid processing cell having at least a first conduit defining a first passage with at least one gas-permeable wall capable of passing the at least one pre-selected dissolved gas from the sample liquid into a reagent fluid. The at least one gas-permeable wall substantially resists flow of the sample liquid therethrough. Reagent fluid is directed through the first conduit while moving the sample liquid and the reagent fluid relative to each other in one of a concurrent and a countercurrent flow relationship to achieve either partial or full equilibration between the sample liquid and reagent fluid to generate at least partially equilibrated reagent fluid in a substantially continuous manner.

Abstract: An improved sensor fish with robust design and enhanced measurement capabilities. This sensor fish contains sensors for acceleration, rotation, magnetic field intensity, pressure, and temperature. A low-power microcontroller collects data from the sensors and stores up to 5 minutes of data on a non-volatile flash memory. A rechargeable battery supplies power to the sensor fish. A recovery system helps locating sensor fish. The package, when ready for use is nearly neutrally buoyant and thus mimics the behavior of an actual fish.

Abstract: Processes for producing acetic acid and determining corrosion therein are described herein. The processes generally include contacting methanol and carbon monoxide in the presence of a liquid reaction medium under carbonylation conditions sufficient to form acetic acid, wherein the liquid reaction medium includes: a carbonylation catalyst selected from rhodium catalysts, iridium catalysts and palladium catalysts; from 1 wt. % to 14 wt. % water; and one or more, in-situ generated derivatives of the one or more additives and combinations thereof; wherein the one or more additives are independently selected from non-benzoyl containing pentavalent phosphine oxides, compound mixtures of at least four phosphine oxides and pentavalent aryl or alkaryl phosphine oxides including one or more benzoyl groups; and recovering acetic acid from the process.

Abstract: In a method of resolving a contribution ratio to soil contamination by a plurality of polluters through a sequential extraction scheme and a stable isotope analysis scheme, Pb stable isotopes are eluted at 5 types of “cation exchange fraction”, “carbonate fraction”, “iron-oxide and manganese hydroxide-fraction”, “organic matters and sulfide fraction”, and “residual fraction” existing at other types and separated from each other in each step. The Pb stable isotopes obtained in each step are analyzed. The contribution ratio to soil contamination by the polluters is resolved through a predetermined resolving equation using the content of a Pb stable isotope in each step based on the content ratio of the Pb stable isotopes. The Pb stable isotopes are 206Pb and 207Pb.

Abstract: A smart cap system includes a cap adapted to fit on a concrete test cylinder, the cap including one or more internal surfaces, and one or more sensors disposed in or on the one or more internal surfaces of the cap, the one or more sensors being adapted to obtain a measurement of a characteristic of a concrete mixture disposed in the test cylinder. The cap may be adapted to fit on one of a 4×8-inch cylinder and a 6×12-inch cylinder. The one or more sensors may include one of a temperature sensor, a humidity sensor, a chronometer, a heat flow sensor, a motion sensor, a pH sensor, a location detector, a GPS sensor, an accelerometer, a triangulation sensor, a thermoelectric heat flow sensor, a salinity sensor, a macro fiber composite (MFC) sensor, and a capillary sensor.

Abstract: Disclosed is a cell analyzer comprising: a measuring device that includes a collecting section configured to collect target cells in a specimen with a filter, and is configured to measure the target cells collected by the collecting section; and a data processing device configured to analyze the target cells based on measurement data obtained by the measuring device, wherein the cell analyzer is operable in a first mode of measuring a clinical specimen collected from a subject and a second mode of measuring a quality control specimen containing particles having size capturable by the filter; and the data processing device is programmed to acquire an amount of particles collected by the collecting section based on measurement data of the quality control specimen obtained in the second mode, and output an alarm when the amount of particles meets a predetermined condition.

Abstract: A cell-based biosensor array includes a base plate having a plurality of substantially transparent areas. The cell-based biosensor array also includes a flexible substrate coupled to the base plate and having disposed thereon a plurality of electrode sets, a plurality of terminal contacts, and a plurality of conductive traces. Each electrode set is disposed proximate a respective one of the substantially transparent areas, and each electrode set includes at least one electrode configured to detect an electric signal. Each terminal contact is associated with a respective one of the at least one electrode and disposed proximate a perimeter of the flexible substrate. Each conductive trace is electrically coupling a respective at least one electrode to the corresponding terminal contact. A first portion of flexible substrate including the electrode sets is disposed on a first surface of the base plate.

Abstract: A single molecule filter includes: a membrane including: a first surface; a second surface; and a membrane aperture disposed in the membrane and traversing the membrane from the first surface to the second surface, the membrane aperture provided to communicate a single molecule across the membrane; and a nanotube disposed on the membrane and including: a first end disposed on the first surface of the membrane; a second end disposed distal to the first surface; and a tubular aperture extending along the nanotube from the first end to the second end, the tubular aperture provided to communicate the single molecule from the second end of the nanotube to the membrane aperture.

Abstract: A method for analyzing droplets is described. The droplets can be received on an outer surface region of a sampler surface disposed on a substrate, wherein the sampler surface is increasingly less hydrophobic along a radial direction toward the center of the sampler surface. Next, the droplets can be aggregated and moved toward the center of the sampler surface. The droplets can then be received at an inner surface region of the sampler surface. Next, the droplets can be analyzed using an analysis mechanism in an area in the inner surface region.

Abstract: Use of acetylated tubulin as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject to said compound, wherein the compound is a furazanobenzimidazoles compound of general formula (I).

Abstract: Use of cell-substrate impedance based methods for screening for agonists of G-Protein Coupled Receptors (GPCRs) or inhibitors of a Receptor Tyrosine Kinases (RTKs), identifying compounds that affect GPCR or RTK pathways, validating molecular targets involved in a GPCR or RTK signaling pathways, monitoring dose-dependent functional activation of GPCR or RTK; determining desensitization of a GPCR and identifying a compound capable of affecting RTK activity in cancer cell proliferation.

Abstract: The present invention provides a method for detecting a disease at a very low concentration of diseased biological subject by contacting the diseased biological subject with a micro-device which comprises: a first sorting unit capable of directly detecting an intrinsic property of the biological subject at the microscopic level and sorting the biological subject by the detected intrinsic property; a first detection unit capable of detecting the same or different property of the sorted biological subject at the microscopic level; and a first layer of material having an exterior surface and an interior surface, wherein the interior surface defines a first channel in which the biological subject flows through the first sorting unit, and then the sorted biological subject flows from the first sorting unit to the first detection unit.

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

Abstract: To provide a more convenient and more accurate method of assaying ProGRP by improving the stability of ProGRP which is known to be unstable in a biological sample. By using a blood sample in a condition in which a blood coagulation factor is not activated is used as a sample, the degradation of ProGRP is suppressed, whereby it is possible to store a sample for a long period of time and to improve the accuracy of an assay.

Abstract: The invention relates to methods of reliably and quantitatively determining the amount of an analyte of interest in a fluid sample using a flow-induced assay, such as an immunochromatographic assay, in which spatiotemporal measurements are recorded during the course of the assay reaction, generating a spatiotemporal dataset, and subsequently analyzed. The invention also relates to a system incorporating instruments for recording spatiotemporal datasets (spatiotemporal data recorders), devices comprised of flow-induced assays configured for analysis on a spatiotemporal recorder, and programs for analyzing the recorded spatiotemporal datasets.

Abstract: The invention provides immunochromatographic test strips and methods for detecting and quantifying S-Adenosylmethionine (SAM), S-Adenosylhomocysteine (SAH) and Homocysteine (HCy) in a sample, comprising: (a) making fluorophore conjugated antibodies; (b) immobilizing SAM, SAH and HCy on a solid support; (c) providing a sample, combining said sample with a conjugate selected from the group consisting of lanthanide chelate conjugates and quantum dot conjugates (QD) with anti-SAM, anti-SAH or anti-HCy, wherein said combining is performed under conditions that allow formation of a competitive complex comprising said conjugate, said SAM, SAH or HCy on the solid support and SAM, SAH or HCy in a sample when present; and (d) detecting the presence of the complex, if present, by monitoring a spectral emission mediated by the fluorescent conjugates in the complex, wherein the emission indicates the presence and quantity of SAM, SAH or HCy in the sample.