Abstract: The invention relates to a device for ear massage, comprising a plate with a massage part. The device has two drives which can be controlled independently from each other and are motion-coupled to the plate at least to some extent by means of coupling elements.

Abstract: Embodiments disclosed herein mitigate motion sickness by disrupting, controlling, or influencing anatomy of the vestibular system. An embodiment may induce vibrations in the vestibular system, including otoliths and/or semicircular canals of the inner ear, causing noisy or unreliable sensory information to be sent to the brain from the vestibular system. Due to the noisy or unreliable quality, the brain, as part of a normal physiological response, may rely less on sensory information from the vestibular system and rely more on other sources, thereby mitigating the motion sickness response, vertigo, vestibular migraines, and other physiological responses to inconsistent sensory information. Vibrations in the vestibular system may be induced by an agitator placed on an individual's head near the vestibular system, or by a transducer placed near the eardrum or directly on an individual's head. Some embodiments may optionally include implantable components in addition to extracorporeal components.

Abstract: Safety mechanisms for compression belt cartridges used in chest compression devices. The safety mechanisms include a breakable link, liner socks, belt guards and a rapid-release connector. The breakable link ensures that unsafe belt tension will not occur. The liner socks protect the patient from friction and contain the breakable link. The belt guards protect foreign objects from entering the belt drive platform. The rapid-release connector allows the belt to be removed safely even during compressions.

Abstract: A system for assisting a rescuer in providing resuscitative treatment to a victim is described. The system includes a motion sensor configured to generate motion sensor signals that are indicative of motion of the chest of the victim during chest compressions, an input device configured to receive user input indicative of a type of chest compressions, an output device, and a processor, a memory, and associated circuitry, the processor communicatively coupled to the motion sensor, the input device, and the output device and is configured to receive the motion sensor signals and the user input indicative of the type of chest compressions, determine chest compression feedback for the rescuer based on the motion sensor signals, and control the output device to selectively provide the chest compression feedback for the rescuer based at least in part on the type of chest compressions indicated by the user input.

Abstract: A manifold to be used in a hot tub plumbing system is provided, the manifold including an intake port configured to be coupled to a water pump in the hot tub plumbing system, and a plurality of output ports configured with connecting portions to connect with tubing to supply water from the water pump to a corresponding plurality of jets in the hot tub plumbing system.

Abstract: Embodiments are directed to a spherically shaped bottle. The spherically shaped bottle may be configured to hold and dispense ingestible pills, including tablets, capsules, or other ingestible products. The spherically shaped bottle may include a container body that holds the ingestible pills within an internal volume. A cap may be pivotally coupled with the container body and configured to cover the internal volume. The cap may define a spherical outer surface of the container with the container body when closed. The spherically shaped bottle may include a neck above the internal volume configured to dispense ingestible pills when the spherically shaped bottle is tilted.

Abstract: An intravenous (IV) bag cover including a body of material; an IV pole/rack attachment mechanism disposed in the body of material; an ornamental feature disposed on at least a portion of one side of the body of material; and wherein the IV bag cover is configured such that when attached to an IV pole/rack it covers substantially all of at least one side of an IV bag installed on the IV pole/rack.

Abstract: An intelligent continuous manufacturing method via liquid cooling of dripping pills comprises the following steps:(1) feeding: weighing and transferring multiple materials respectively; (2) material combining: performing staged heating on the materials transferred in step (1), and mixing the same to obtain a material mixture, wherein an RSD of an effective ingredient in the material mixture ?5%; (3) homogenizing: pressurizing the material mixture obtained in step (2), and increasing the temperature, so as to obtain a homogenized material having the RSD of the effective ingredient in the material mixture ?5%; (4) dripping: performing vibration dripping on the homogenized material obtained in step (3) to obtain dripping pills, delivering the dripping pills into a cooling liquid to be cooled and then transferred; and (5) de-oiling: removing the cooling liquid on surfaces of the dripping pills obtained in step (4) via tilting centrifugation.

Abstract: A nipple adapter for feeding babies solid food from a milk nipple they already use for milk is disclosed. A nipple adapter is screwed onto a food pouch and into a milk nipple such that the food from the pouch can be fed to the baby through the milk nipple the baby already uses for milk.

Abstract: A foldable bottle includes a bottle body, which has a first annular wall extending in a top-bottom direction, a top connection wall extending upwardly from the first annular wall, a second annular wall extending downwardly from the first annular wall, a third annular wall extending downwardly and foldably from the second annular wall, and a bottom wall connected to the third annular wall. The bottle body is changeable between an unfolded state, where the second annular wall and the third annular wall are unfolded to extend outwardly and downwardly from the first annular wall, and a folded state, where the second annular wall and the third annular wall are folded and inserted into the first annular wall.

Abstract: Methods and devices for orally administering fluids and medical instrumentation to individuals for the promotion of health are disclosed. An apparatus is described comprising a cartridge including a cartridge body defining a reservoir and a cartridge spout extending proximally from the cartridge body and terminating at an aperture. A cartridge seal is attached to a proximal tip of the cartridge spout, wherein the cartridge seal hermetically seals the liquid within the cartridge, and wherein the cartridge seal is detachable from the proximal tip of the cartridge spout and permanently coupled to the cartridge at a location distal to the cartridge spout. A proximal cartridge seal portion is positioned proximal to the location of permanent coupling and is moveable away from the cartridge aperture once the cartridge seal is detached from the proximal tip of the cartridge spout.

Abstract: A hygienic pacifier includes an annular folding structure formed on a substantially spherical shield that joins a nipple to a faceplate and that is movable between a recoiled storage position in which the shield substantially surrounds the nipple and an extended use position in which at least a portion of the nipple projects through the nipple access opening and is exposed for use. The annular folding structure may be used to bias the shield to remain in the extended use position when the shield is placed in the extended use position. Further, in some instances, the annular folding structure may be configured to provide a bias that may be overcome by a moderate impact to the pacifier such as an impact associated with dropping the pacifier.

Abstract: A photoactive solution and a micro-bubble solution are provided as part of a system for use in disinfecting a root canal. The system also include a handpiece having a flexible tip. When the handpiece is energized, vibrations are induced in the flexible tip to mechanically activate the micro-bubble solution in the root canal. The photoactive solution contains a photoactive compound dissolved in an alcohol carrier solution; and the micro-bubble solution contains an oxygen carrier, an oxidizing agent and a surfactant. The flexible tip transmits light energy into the root canal. The micro-bubble solution facilitates delivery of the light to the photoactive solution to activate the photoactive solution in the canal. The activated photoactive solution then acts on the oxygen introduced in the canal via the micro-bubble solution to disinfect the root canal.

Abstract: Cellulose cyanoacrylate is employed to bond two surfaces, fill voids or duplicate the shape of a three-dimensional object, Two surfaces may be bonded by placing a sheet of cellulose material between the surfaces and applying cyanoacrylate glue around the edge of the sheet until saturated and allowing it to cure. Paper toweling may favorably be employed as the cellulose material. A break or fracture in an article can be overlaid with a sheet of cellulose that when saturated with cyanoacrylate glue and temporarily held in place and shaped with a releasable film, the fracture can be corrected. A dry powder comprising highly abrasion-resistant particles can be mixed with the cellulose material to enhance abrasion resistance and to improve long-term color stability—especially important for dental cavity treatment. To duplicate the shape of a three-dimensional object, a sheet of releasable film is placed over the object, followed by a sheet of cellulose that is then saturated with cyanoacrylate glue.

Abstract: Described herein is a method of treating the hair including providing a concentrated hair care composition in an aerosol foam dispenser. The concentrated hair care composition includes one or more silicones, perfume, stearyl alcohol, and cetyl alcohol. The method also includes dispensing the concentrated hair care composition from the aerosol foam dispenser as a dosage of foam; applying the foam to the hair; and rinsing the foam from the hair. The foam has a density of from about 0.025 g/cm3 to about 0.30 g/cm3 when dispensed from the aerosol foam dispenser.

Abstract: The present invention provides an oil-in-water type cosmetic that is excellent in the dispersion stability of an ultraviolet scattering agent, can provide a refreshing feel and light sense of use with no stickiness to the skin, and also has a high ultraviolet-shielding effect; and a sunscreen cosmetic comprising the oil-in-water type cosmetic. The oil-in-water type cosmetic comprises: (A) an ultraviolet scattering agent; (B) a nonionic surfactant; (C) a modified polyalkylene oxide represented by formula (I) (D) an oily component; and (E) water.

Abstract: A method of treating the hair including applying to the hair a shampoo composition, rinsing the shampoo composition from the hair, applying to the hair a concentrated conditioner composition, and rinsing the concentrated conditioner composition from the hair. The shampoo composition includes an anionic surfactant, one or more amphoteric, non-ionic, or zwitterionic co-surfactants, and less than 0.25% of one or more shampoo high melting point fatty compounds. The concentrated conditioner composition includes one or more silicones, perfume, and from about 2% to about 10% of one or more conditioner high melting point fatty compounds.

Abstract: To increase the esthetic property by removing stains deposited on the dental surface, there is provided a stain-removing oral composition containing 0.33% by weight to 2.0% by weight of sodium metaphosphate.

Abstract: Zinc oxide powder of the present invention contains zinc oxide particles, in which primary particles of the zinc oxide particles have a minor axis of 35 nm or more and 350 nm or less and have a Heywood diameter of 35 nm or more and 400 nm or less, and a coefficient of variation of a number distribution of the Heywood diameters of the primary particles of the zinc oxide powder is 50% or less.

Abstract: A skin disinfectant composition containing an aliphatic alcohol (0.1-90% w/w), a chelating agent (0.1-5%), a hydrotrope (0.1-5.0%), an acid to adjust the pH (0.01-5%), a C10 to C16 alkylbenzene sulfonate (0.1-1.0%), a chaotrope (0.01-10%), a sesquiterpenoid (0.01-1%), a skin moisturizing, conditioning and/or emollient agents (0.01- 10%) and water to balance. The composition can be a liquid, foamable or it can be a thickened gel.

Abstract: Cosmetic composition comprising at least 35% by weight of a powder component and a binding component characterized in that it comprises at least one ester selected from neopentylglycol dipelargonate, glycerol tripelargonate, pentaerythritol tetrapelargonate and mixtures thereof.

Abstract: Leave-on compositions to be applied to the skin, which after five minutes post-application provides an improved low residue level, where the composition includes an emulsifier having a particular HLB value and an emollient present in a weight amount that is equal to or greater than the weight amount of the emulsifier.

Abstract: Leave-on compositions to be applied to the skin, which after five minutes post-application provides an improved low residue level, where the composition includes an emulsifier having a particular HLB value and an emollient present in a weight amount that is equal to or greater than the weight amount of the emulsifier.

Abstract: The antimicrobial foaming composition of the present invention comprises a cationic active ingredient, a cationic compatible surfactant, a foam booster, a foam structure enhancing agent, dermal adjuvants, and a carrier. The present antimicrobial compositions are free of the antimicrobial agents triclosan (i.e., 2,4,4?-trichloro-2?hydroxy-diphenylether) and lower alcohols. They are also free of anionic surfactants. The foaming compositions have rapid cidal activity, provide stable, copious foam, and exhibit enhanced tissue (e.g. skin) compatibility.

Abstract: The present disclosure relates generally to oral compositions and methods for oral cleansing and reducing salivary bacteria, and more particularly, to oral compositions comprising a combination of magnolia bark extract (MBE) and L-arginine, N?-lauroyl ethyl ester (LAE). The oral compositions are useful for improving oral health, including freshening breath and reducing total salivary bacteria.

Abstract: Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.

Abstract: This invention relates to a group of compounds for repelling blood-feeding ectoparasitic arthropods, and a method of deterring their landing and feeding on animals including humans, by applying in one or more formulations compounds that incorporate one or more sulfide and one or more hydroxyl groups to the skin, clothing or environment of animals, including humans. A method of repelling and deterring landing and feeding by blood-feeding arthropods on an animal by applying in effective amount one or more compounds that incorporate alkyl sulfide and alcohol moieties, or alkyl sulfide and amide moieties, or alkyl sulfide and amide moieties to the skin, clothing or environment of an animal.

Abstract: The invention provides a personal cleansing composition having a pH ranging from 4.5 to 5.1 and comprising, in an aqueous continuous phase: (i) one or more anionic cleansing surfactants; (ii) one or more dispersed benefit agents selected from hydrophobic emulsion droplets and particulate solids, and (iii) a structuring polymer selected from alkali swellable emulsion (ASE) polymers and hydrophobically modified alkali swellable emulsion (HASE) polymers; characterized in that the one or more anionic cleansing surfactants are selected from alkyl ether sulphates of general formula (I): R—O—(CH2CH2—O)n—SO3?M+ in which R is a straight or branched chain alkyl group having 10 to 14 carbon atoms, n is a number that represents the degree of ethoxylation and ranges from 3 to 3.5, and M is an alkali metal, ammonium or alkanolammonium cation.

Abstract: The invention provides a compound of formula (I) wherein: A, B, C, D, W, X, Y and Z are each independently selected from H and OH; or a salt thereof; for use in the treatment and/or prevention of a skin condition in a subject, wherein the compound of formula (I) or salt thereof is administered topically. The invention further provides topical compositions of a compound of formula (i) and processes for the preparation of said compositions.

Abstract: Disclosed herein are a tooth whitening compositions comprising at least one hydrophobic polymer carrier; cetylpyridinium chloride; and at least one whitening agent, wherein the composition is free of water. Also disclosed herein are methods for reducing microbial growth on the surface of an oral care device comprising contacting the oral care device with saliva and a tooth whitening composition comprising at least one hydrophobic polymer carrier; cetylpyridinium chloride; and at least one whitening agent, wherein the composition is free of water.

Abstract: Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of sclareolide, ginger root CO2 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, purple coneflower pressed juice or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.

Abstract: The present invention relates to a composition for dyeing keratin fibers, comprising (a) at least one direct dye; and (b) at least one oxygen-containing polycyclic compound which has at least one oxygen-containing polycyclic ring. The composition according to the present invention may further include (c) at least one specific sulfone compound. The composition according to the present invention is a one-part composition and can prevent or reduce skin staining by the direct dye on the skin such as the scalp, while providing the keratin fibers with good cosmetic effects such as good coloring properties.

Abstract: The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium: an aqueous phase, spiculisporic acid, at least one non-sulfate and non-sulfonate surfactant, and at least one base, wherein the ratio R1 of number of moles of base over the number of moles of spiculisporic acid is strictly greater than 1.

Abstract: The invention relates to a cosmetic composition, especially a hair composition, and to a method for the cosmetic treatment of keratin materials, especially of the hair, employing compounds of formula: in which Z represents (i) a hydrogen atom, (ii) a linear or branched C1 to C32 (saturated) alkyl radical; (iii) a linear or branched C2 to C32 (unsaturated) alkene radical, comprising one or two C?C double bonds; (iv) an aryl-substituted alkyl radical; said radicals being optionally substituted and/or interrupted.

Abstract: The present invention provides compositions and methods for treating a dermatological disorder or disease.

Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.

Abstract: A volatile oily composition includes from 50 to 100% by weight of a mixture of paraffins and from 0 to 50% by weight of at least one non-volatile oil. Cosmetic compositions containing the abovementioned oily composition, and the cosmetic uses of the cosmetic compositions, particularly for making up and/or caring for and/or protecting skin, lips, eyelashes and/or nails, and in antiperspirant/deodorant compositions are also described.

Abstract: Core-shell particles have a hydrophobic core and a shell formed of o containing hyperbranched polymers (HP). The HP can be covalently bound to the one or more materials that form the core or coated thereon. The HP coating can be modified to adjust the properties of the particles. For example, unmodified HP coatings resist non-specific protein absorption. Alternatively, the hydroxyl groups on the HP coating can be chemically modified to form functional groups that react with functional groups on tissue to adhere the particles to the tissue, cells, or extracellular materials, such as proteins. Such functional groups include, but not limited to, aldehydes, amines, and O-substituted oximes. Topical formulation for application to the skin contain these HP coated nanoparticles. In some embodiments, the particles include cosmetic, therapeutic, diagnostic, nutraceutical, and/or prophylactic agents, such as those used as sunblock compositions.

Abstract: A method of treating the hair including providing a concentrated hair care composition in an aerosol foam dispenser. The concentrated hair care composition includes one or more silicones, perfume, and less than 10% high melting point fatty compounds. The method also includes dispensing the concentrated hair care composition from the aerosol foam dispenser as a dosage of foam; applying the foam to the hair; and rinsing the foam from the hair. The foam has a density of from about 0.025 g/cm3 to about 0.40 g/cm3 when dispensed from the aerosol foam dispenser.

Abstract: The present disclosure generally relates to approaches for improving water absorption and retention by the skin's surface. In particular, the disclosure provides compositions and methods for preparing mixtures comprised of ethoxylated oils and water or mixtures comprised of micro or nano emulsions and water, which provide enhanced skin hydration or moisturization to a subject.

Abstract: The present disclosure relates to processes for preparing a skincare product, the process comprising drying a black soldier fly to produce a dried black solder fly; extracting the dried black soldier to produce an oil extract or a fat extract of the black soldier fly; separating the oil extract or the fat extract of the black soldier fly from the mixture to produce a separated oil extract or fat extract of the black soldier fly; sterilizing the separated oil extract or fat extract of the black soldier fly to produce a sterilized oil extract or fat extract of the black soldier fly; and mixing the sterilized oil extract or fat extract of the black soldier fly with additional ingredients to form the skincare product, wherein the pharmaceutical product contains the sterilized oil extract or fat extract of the black solder fly.

Abstract: A method for protecting skin is provided. The method comprises administering to a subject in need a composition, wherein the composition comprises an effective amount of a Camellia sinensis callus extract, and the extract is a polar solvent extract of calluses of Camellia sinensis leaves. The method is especially for nursing skin, repairing skin, improving skin condition, delaying skin aging, assisting in maintaining content of collagen in skin, against photodamage, preventing skin lesions, and/or promoting wound healing.

Abstract: A serum for improving the youthful appearance of skin by reducing the appearance of fine lines and wrinkles may include sodium silicate; glycerin extract; pullulan; propylene glycol; magnesium aluminum silicate; and xanthan gum. The serum may also include water; rosa damascena flower extract; acetyl hexapeptide—8, caprylyl glycol, water extract; cucumis sativus fruit extract; glycyrrhiza glabra root extract; phenoxyethanol; and ethylhexylglycerin. The serum may be made by a specific process to ensure desired properties.

Abstract: A skin whitening composition includes ?-mangostin or a cosmetically acceptable salt thereof as an effective ingredient. ?-Mangostin represented by Chemical Formula 1 suppresses the expression of tyrosinase and TRP-1 (tyrosinase-related protein-1) and induces autophagy of a melasosome. As such, it was confirmed that the ?-mangostin not only suppresses melanin production but also exhibits the effect of removing previously formed melanin. Accordingly, the ?-mangostin can be advantageously used as a functional material for skin whitening and skin lightening.

Abstract: The disclosure provides compositions and methods for the prophylaxis and/or treatment of radiation dermatitis or erythema.

Abstract: Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated from ginseng root. The composition contains ginseng-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

Abstract: The present invention provides an all natural composition comprising naturally-obtained plant extracts.

Abstract: The present specification discloses a composition for preventing hair loss or promoting hair growth comprising, as an active ingredient, extracellular follicles derived from lactic acid bacteria, and a method for preparing the extracellular follicles derived from lactic acid bacteria. The composition has an effect of preventing and prohibiting hair from falling off from the scalp or becoming thin or tapered. In addition, the composition has an effect of implementing a hair growth function for generating new hair, or a function for promoting the hair growth, as well as a function of promoting a delay from an anagen to a catagen phase of a hair cycle and a function of growing the existing hair healthy.

Abstract: The present invention is directed to treatments for a disease or condition, in a subject in need thereof, that provide alternatives to treatment by injection that give, relative to treatment by injection, improved treatment outcomes, 100% treatment compliance, reduced side effects, and rapid establishment and/or termination of substantial steady-state drug delivery. The method includes providing continuous delivery of a drug from an implanted osmotic delivery device, wherein substantial steady-state delivery of the drug at therapeutic concentrations is achieved within about 7 days after implantation of the osmotic delivery device in the subject and the substantial steady-state delivery of the drug from the osmotic delivery device is continuous over a period of at least about 3 months. In one embodiment, the present invention is directed to treatment of type 2 diabetes mellitus using insulinotrophic peptides. In embodiments, a subject has a baseline HbA1c % of greater than 6.5% or 10.0%.

Abstract: The present invention relates to osmotic delivery devices, formulations, and methods for delivery of two or more beneficial agents. In one aspect, the present invention provides osmotic delivery devices useful for substantially concurrent administration of two or more beneficial agents. In another aspect, the present invention provides beneficial agent formulations for use in the osmotic delivery devices. The formulations include formulations wherein beneficial agents are soluble in the vehicle, suspension formulations comprising particle formulations of one or more beneficial agent, and combinations thereof. Further, methods for treatment of a variety of diseases or conditions using two or more beneficial agents are disclosed, wherein the methods are preferably practiced using the osmotic delivery devices and/or formulations of the invention.