Abstract: A pulse wave transit time measurement device includes a pulse wave transit time calculator that calculates a pulse wave transit time based on a peak time difference between an electrocardiographic signal and a pulse wave signal, a posture classifier that classifies time serial data of the pulse wave transit time based on a posture detected by an acceleration sensor, and a fluctuation identifier that sets a reference posture from among classified postures, corrects, in conformity with the reference posture, the time serial data of the pulse wave transit time classified into the posture different from the reference posture, and determines fluctuations in the pulse wave transit time based on the time serial data of the pulse wave transit time in the reference posture and the time serial data of the pulse wave transit time having being corrected.

Abstract: This instant disclosure provides a heart rate detecting module which includes an image sensor and a processor. The image sensor generates a plurality of image frames according to a light from a subject. The processor outputs a heart rate value based on a light intensity variance of the plurality of image frames. This instant disclosure further provides a heart rate detecting method which includes the following steps. A plurality of image frames are generated according to a light from a subject by an image sensor, and a heart rate value is outputted based on a light intensity variance of the plurality of image frames by a processor.

Abstract: An integrated physiological signal acquisition system comprises an analysis host, a physiological signal acquisition element and at least one biological sensor coupled to the physiological signal acquisition element for sensing a physiological signal of a user. The physiological signal is transmitted to the physiological signal acquisition element. The physiological signal acquisition element transmits the physiological signal to the analysis host for analysis. The at least one biological sensor is a pluggable biological sensor. Accordingly, only an analysis host and a physiological signal acquisition element are need to you realize different physiological signal detection, thus, the cost of hardware can be significantly reduced.

Abstract: An analog front-end system and method for Electromyography (EMG) signal acquisition in wearable applications. The system includes filters for restricting the bandwidth of captured EMG signals, a multiplexer, an amplifier, and a microcontroller unit having an analog-to-digital converter for converting the analog EMG signals into digital signals. In the system and method, the bandwidth of the EMG signals is filtered before the EMG signals are multiplexed by the multiplexer, and the EMG signals are multiplexed by the multiplexer so that one amplifier is used for amplifying the EMG signals before they reach the analog-to-digital converter. The EMG signals are acquired by multilayered sensors applied to wearable apparel, and a connector transfers the body signals from the multilayered sensors to a central device having the analog front-end system for computing, monitoring, and sending the body signals to a display.

Abstract: The exemplary systems and methods may be configured to generate a dispersion signal from a plurality of cardiac signals and determine a QRS onset time value and a QRS offset time value from the plurality of cardiac signals. The QRS onset and offset time values may be used to measure, or capture, activation times.

Abstract: The invention relates to a portable device for video electroencephalography. The device has a central portion to which a plurality of arcuate arms are directly or indirectly connected in a movable manner. The arms together define a helmet structure adapted to be worn on the head of a patient, arm is configured to allow mounting of one or more electrodes which are connected to an electronic central unit mounted on the helmet structure. The device also has a supporting member and a video camera mounted on the supporting member so as to face the helmet structure, said video camera. The arms have a first arm and a second arm which extend away from each other in a longitudinal direction (L), as well as a third arm and a fourth arm which extend away from each other in a front direction (F). The first and second arms are pivoted on the central portion about respective axes parallel to the front direction (F), and the third and fourth arms are pivoted about respective axes parallel to the longitudinal direction (L).

Abstract: MRI interference with a co-existing treatment system may be reduced or avoided by carrying out RF-sensitive operations of the treatment system only when gradient field activity of the MRI system is suppressed.

Abstract: A physiological signal receiving apparatus and a manufacturing method thereof are provided. The physiological signal receiving apparatus includes an electrode layer, a protective layer and a conductive structure electrically connected to the electrode layer. The electrode layer is disposed on a substrate. The electrode layer includes a porous gel and a plurality of conductive particles distributed therein. The protective layer is disposed on the substrate and the electrode layer. The protective layer has an opening exposing a portion of the electrode layer. The porous gel is expanded after absorbing liquid, such that a surface of the electrode layer exposed by the opening is higher than a surface of the protective layer.

Abstract: Determining a state of water deficiency in a human body during daily life activities is done by measuring an impedance of a portion of the human body at a low frequency and at a high frequency. An amount of fluid in the body tissues in the volume under study is assessed based on the impedance at the high frequency. A current amount of extracellular fluid in the tissues in the volume is assessed based on the impedance at the low frequency. A reference value of the assessed amount of extracellular fluid in the tissues is preselected at the start of measurements. A correction value is determined based on the changes in blood amount in the volume at the current measurement time. A corrected assessment value is the determined. Using the corrected assessment value, the onset of water deficiency is determined.

Abstract: An image acquisition unit sequentially acquires an endoscope image of a tubular structure having a plurality of branch structures, and an image generation unit generates an image of the tubular structure. A first certainty factor calculation unit calculates a first certainty factor indicating a possibility of presence of the endoscope within the tubular structure. A second certainty factor calculation unit calculates a second certainty factor indicating a possibility of presence of the endoscope by performing matching between the image of the tubular structure and each of the endoscope images at each of a plurality of positions within the tubular structure. A current position specifying unit specifies the current position of the endoscope based on the first and second certainty factors.

Abstract: System and methods for rendering key respiratory measurements accessible to hand-held mobile electronic devices with acoustic input capabilities. A whistle having a pre-determined correlation (between through-flowing airflow per unit time and frequency of acoustic emissions from the whistle) may generate or transmit information or signals. A processor in the mobile electronic device may receive the information or signals, determine a baseline acoustic context, and/or record samples. The processor may determine a frequency value for an acoustic signal (based on the recorded samples), determine an expiratory airflow rate value (based on the frequency value), and determine a respiratory parameter (based on the expiratory airflow rate value). The processor may also determine whether the acoustic signal corresponds to a whistle signal that is generated by a user performing a forceful exhalation through the whistle. The processor may generate and render spirometric information.

Abstract: An acetone concentration estimate device acquires a measured acetone concentration measuring acetone excreted from a user, acquires an elapsed time which has elapsed since the user ate a meal, and estimates an acetone concentration, which is a ketone body concentration of when an amount of change in blood sugar level of the user per given unit of time is stable, based on the acquired current measured acetone concentration and on the acquired elapsed time, and outputs information corresponding to the estimated acetone concentration.

Abstract: Provided is a chest measuring device configured to be attached to and detachable from a body and capable of inducing a correct posture of a subject and at the same time, correcting an abnormal alignment of the spine by analyzing measured values of left and right chests and generating vibrating motion to a chest that needs stimulation, a scoliosis correction system enabling a subject to conveniently measure his/her spinal condition alone without the help of others by including sensors contacting left and right ribs and left and right transverse processes of lumbar vertebrae of the subject and also including a wearable internet of things (IoT) capable of detecting sensing values of muscles used to determine a spinal condition of the subject, a system for remotely diagnosing spine remotely diagnosing the spine of a patient by processing trunk movement data of the patient collected through a wearable measuring device, and a wearable measuring device enabling a subject to self-diagnose a spinal condition and corre

Abstract: A portable sampling device (1) for collecting particles in a stream of exhaled breath comprising a housing (10) with an inlet (11) and an outlet (12) arranged to guide the stream of exhaled breath therethrough, a collecting device holder (20) arranged at least partially inside the housing and comprising at least one flow path (21) in fluid connection with the inlet in which a collecting device (30) is arranged, the collecting device being adapted to collect the particles in the exhaled breath, wherein the collecting device has a diameter smaller than the flow path diameter and is movably arranged in the collecting device holder.

Abstract: Technologies for indicating the detection of toe walking include a gait monitoring device that includes one or more sensors usable to collect gait data relative to the gait monitoring device and vibration circuitry that includes a vibrating motor usable to provide haptic feedback in the form of a vibration. The gait monitoring device is configured to analyze the gait data collected from the one or more sensors, detect a toe walking event as a function of the analysis of the collected gait data, and enable, subsequent to having detected the toe walking event, the vibrating motor for a predetermined period of time. Additional embodiments are described herein.

Abstract: A location detection system identifies the locations of medical devices such as patient support apparatuses and/or patient care devices within a medical facility. The devices communicate via a wired connection to one or more medical facility systems (e.g. nurse call system, computer network, etc.), and/or via a wireless connection to such systems. The location detection system automatically determines location information of the devices and communicates the location information so that the recipient of any outgoing alerts and/or other information sent from the devices is apprised of the location of the particular device sending the alert or other information. Caregivers are thereby able to respond to the correct location of an alert, and software systems such as EMR systems, admission discharge and transfer (ADT) systems, etc. are able to correlate transmitted device data with the location and/or patient assigned to that location.

Abstract: The present invention relates to a fall detection device, which includes a sensor attached to a user and sensing a motion of the fall detection device in a plurality of coordinate axial directions; an output section capable of outputting fall information of a user; and a controller determining that the user falls down when acceleration in a first axial direction among the plurality of coordinate axial directions is changed from a positive value to a negative value based on the motion sensed by the sensor, and controlling the fall information to be output.

Abstract: A rehabilitation system includes a portable patient workstation configured to facilitate in-home rehabilitation therapy. In some embodiments, the workstation includes a computing device and one or more rehabilitation devices. The computing device is configured to generate computer-based tasks associated with one or more in-home exercises. The rehabilitation devices, communicatively coupled to the computing device, includes a sensor that captures movement data for use in evaluating a patient's motor skills when instructed to perform one or more of the tasks.

Abstract: Hearing difficulties are the most commonly reported disabilities among Veterans. Blast exposures during explosive events likely play a role, given their propensity to directly damage both peripheral auditory system (PAS) and central auditory system (CAS) components. Post-blast PAS pathophysiology has been well-documented in both clinical case reports and laboratory investigations. In contrast, blast-induced CAS dysfunction remains under-studied, but has been hypothesized to contribute to an array of common Veteran behavioral complaints including learning, memory, communication, and emotional regulation. This investigation compared the effects of acute blast and non-blast acoustic impulse trauma in adult male Sprague-Dawley rats. An array of audiometric tests were utilized, including distortion product otoacoustic emissions (DPOAE), auditory brainstem responses (ABR), middle latency responses (MLR), and envelope following responses (EFR).

Abstract: Analyte sensor connectors that connect analyte sensors, e.g., conductive members of analyte sensors, to other devices such as sensor electronics units, e.g., sensor control units, are provided. Also provided are systems that include analyte sensors, analyte sensor connectors, and analyte sensor electronics units, as well as methods of establishing and maintaining connections between analyte sensors and analyte sensor electronics units, and methods of analyte monitoring/detection. Also provided are methods of making analyte sensor connectors and systems that include analyte sensor connectors.

Abstract: The disclosure provides: a two-way communication means between a sweat sensing device and a user; at least one means of activating, deactivating, controlling the sampling rate, and controlling the electrical power applied to a particular sweat sensor or group of sensors; a means of isolating a sweat sensor from sweat until needed; a means of selectively stimulating sweat for a particular sweat sensor or group of sensors to manage sweat flow or generation rate; a means of monitoring the power consumption of a sensor device, individual sensors or groups of sensors; a means of monitoring an individual sweat sensor or group of sensors for optimal performance; a means of monitoring whether a sweat sensing patch is in adequate proximity to a wearer's skin to allow device operation; and the ability to use aggregated sweat sensor data correlated with external information to enhance the device's management capabilities.

Abstract: A wearable sensing platform includes sensors and circuits to sense aspects of a user's state by analyzing bodily fluids, such as sweat and/or urine, and a user's temperature. A sensor array senses a plurality of different body fluid analytes, optionally at the same time. A signal conditioner is coupled to the sensor array. The signal conditioner conditions sensor signals. An interface is configured to transmit information corresponding to the conditioned sensor signals to a remote computing device. The wearable sensing platform may include a flexible printed circuit board to enable the wearable sensing platform, or a portion thereof, to conform to a portion of the user's body.

Abstract: Embodiments include methods, systems, and apparatus for identification, detection, and removal of cancerous cells from a patient. The apparatus includes an apparatus handle. The apparatus also includes a display including a pH measurement result. The apparatus also includes an apparatus tip including a reference electrode and a plurality of sensing surfaces, wherein each of the plurality of sensing surfaces is connected to a base of a bipolar junction transistor (BJT) device. The BJT device further includes a collector and an emitter. The apparatus also includes automation circuitry including a processing unit in communication with the apparatus tip and the display. The plurality of sensing surfaces includes a conducting material.

Abstract: A body composition change prediction device acquires a measured acetone concentration measuring acetone excreted from a user, acquires current body composition information and past body composition information of the user, computes a prediction value predicting the body composition information at a given future point in time based on information relating to the body composition of the user, and determines a fat burning style of the user based on the acetone concentration and the current body composition information. The body composition change prediction device weights the prediction value based on a weight, the weight being set according to the burning style and being a greater weight the higher the measured ketone body concentration, and outputs information according to the weighted prediction value.

Abstract: Systems and methods for operating a modular pulse oximeter platform with interchangeable modules. The method comprises selecting a plurality of modules based on a health context and connecting in a serial manner the plurality of modules and a pulse oximeter platform via a plurality of connection means. The pulse oximeter interprets identification numbers from the plurality modules and operates the connected plurality of modules accordingly. Data received from the plurality of modules are associated with each other or with pulse oximeter data.

Abstract: A sensor assembly for detecting at least one analyte in a body fluid includes an electrochemical sensor, a body mount that attaches to a body of a user and an inserter that transfers the sensor to the body mount. A first adhesive is attached to one or both of the body mount or the sensor, and the first adhesive attaches the sensor to the body mount. A second adhesive is attached to one or both of the sensor or the inserter and releasably attaches the sensor to the inserter. The assembly has an initial position in which the sensor is attached to the inserter via the second adhesive and a final position in which the sensor is attached to the body mount via the first adhesive. Transferring the sensor from the initial position to the final position releases the sensor from the inserter.

Abstract: In a first aspect, there is a device for detecting a substance within blood, including a collecting tube dimensioned to draw in blood through capillary action; a reagent chamber containing a reactive element; and a connector tube providing fluid communication between the reagent chamber and the collecting tube; wherein the connector tubes are dimensioned to draw in blood through capillary action to the reagent chamber. In other aspects, the device can include an outer casing and/or a plurality of reagent chambers each with a reactive element therein.

Abstract: The present invention concerns a human emotional/behavioural/psychological state estimation system comprising a group of sensors and devices and a processing unit. The group of sensors and devices includes: a video-capture device; a skeletal and gesture recognition and tracking device; a microphone; a proximity sensor; a floor pressure sensor; user interface means; and one or more environmental sensors.

Abstract: The present relates to a method, system and a device for non-invasive detection of urine flow from the bladder into the kidney(s). The method, system and device rely on measurements made at distinct time points and can be used to detect Vesicoureteral reflux. The method, system and device are designed to detect changes in urine volume in the ureter(s), bladder and/or kidney(s). The method and device measure conductivity changes by bioelectrical impedance or electrical impedance tomography technology.

Abstract: An apparatus for measuring work performed by a subject in a magnetic resonance imaging device is provided which includes an actuating bar, an elastomer band positioned inside the actuating bar, a tower and roller bearing, and a pivot base supporting the actuating bar, the elastomer band positioned inside the actuating bar, and the tower and roller bearing. A force-sensing instrument for use in a magnetic resonance imaging device is provided, which includes a strain gauge cemented to a surface of an actuating device that is operable in a magnetic resonance imaging device. A surface coil holder having four degrees of freedom is provided. The surface coil holder is capable of being attached to a scanner table of an exercise apparatus. The surface coil holder includes a coil cradled in the coil holder and secured by hook and loop strips.

Abstract: A method is to be implemented by a computing device and includes steps of: a) identifying, according to a magnetic resonance imaging (MRI) image, brain image regions each of which contains a respective portion of diffusion index values of at least one diffusion index, which results from image processing performed on said at least one MRI image; b) for each of the brain image regions, calculating a characteristic parameter based on the respective portion of the diffusion index values; and c) diagnosing the brain examined with one of predetermined categories of the neurological disorder by performing classification on a combination of the characteristic parameters via a classifier.

Abstract: An apparatus including a body made of force-conveying material, wherein the body includes a nozzle part and a base part, the nozzle part protruding from the base part, and wherein the nozzle part is configured to fit at least partly into a mouth of a subject for feeding the subject, and at least one deformation sensor located in the base part, the deformation sensor being configured to sense, at the base part, deformation conveyed from the nozzle part through the force-conveying material.

Abstract: A system for accessing a patient's uterine cavity and detecting perforations in the uterus includes an elongated probe having a flow channel extending to a terminal outlet in a distal region of the probe. A fluid source is coupled to the flow channel, and a seal on the probe is positionable in an endocervical canal. The probe may be trans-cervically inserted into the uterine cavity, and a fluid may be introduced through the channel to flow outwardly from the terminal outlet into the uterine cavity. A parameter of said fluid flow is monitored to detect a perforation in the uterus.

Abstract: The present technology relates to an information processing apparatus, an information processing method, and a program capable of checking a plurality of types of analysis results regarding one skin condition item intuitively and easily. The information processing apparatus according to one aspect of the present technology includes an acquisition unit configured to obtain information representing a plurality of types of analysis results on skin conditions obtained by analyzing an image of a skin at a same position, and a presentation unit configured to simultaneously display, on a same image, a plurality of types of visualized information obtained from visual representation of the plurality of types of analysis results. The present technology is applicable to a mobile terminal used together with a skin measurement instrument that photographs a skin image.

Abstract: A system and method to send biometric and location-based data to provide live remote fitness advice. The systems allows fitness trainers to receive live biometric and location-based data from the athletes, wherever they are training, in order to improve the fitness performance of the athletes being trained, while they are engaged in a training.

Abstract: The invention relates to a system for characterising the sleep of an individual, the characterisation system comprising: a measuring device for measuring a brain activity signal representing the brain waves; a central electronic unit for identifying, in a range of frequencies of between 9 and 16 Hz, a smaller range of sleep spindles of the individual, the smaller range of sleep spindles comprising the brain wave frequencies of the sleeping individual, having an amplitude higher than 15 ?V and a duration of between 0.5 seconds and 2 seconds, and comparing, with a threshold, at least one parameter of the brain activity signal of the awake individual in the range of frequencies corresponding to the smaller range of sleep spindles; and a communication interface connected to the central unit and used to emit a warning signal perceptible by the individual when the parameter of the brain activity signal in the range of frequencies corresponding to the smaller range of sleep spindles exceeds the threshold.

Abstract: A patient treatment unit for analyzing and treating abnormality of human or animal tissues, includes a display; a pulse generator circuit that outputs a sequence of electrical pulses at a pulse frequency, the electrical pulses having a pulse width, the pulse generator controlling the pulse frequency and the pulse width of the electrical pulses; a pair of probes for contacting a body of a patient and electrically coupled to the pulse generator; and a voltage and current sensing circuit that senses a voltage or a current via the probes when contacting the body of the patient.

Abstract: Methods and systems for determining the concentration of one or more analytes from a sample such as blood or plasma are described. The systems described herein can be configured to withdraw a certain volume of sample from a source of bodily fluid, direct a first portion of the withdrawn sample to an analyte monitoring system and return a second portion of the sample to the patient. The analyte monitoring system can include an automated blood withdrawal system that is configured to withdraw blood from the patient's vasculature at low pressure and/or withdrawal rates so as to reduce or prevent contamination of the withdrawn fluid from the infusion fluids.

Abstract: This invention relates to molecular diagnostics and, more specifically DNA-based tests for the prognosis and/or monitoring of fibrotic disease progression in humans, and processes for stratifying patients based on their likely rates of fibrotic disease progression. The invention also relates to the field of therapy for fibrotic disease, based on such prognoses, monitoring and stratification results, such as in monitoring and/or stratifying and/or treating patients having a higher likelihood of rapid fibrotic disease progression.

Abstract: The present invention relates to a battery module for wireless exchange of data and power between the battery module and another device of a system, in particular of a patient monitoring system, to which said battery module is coupled. The battery module comprises a sealed housing (93), a battery unit (91) for storing electrical energy, a data storage unit (94) for storing data, and a connector (95). Said connector comprises a data transmission unit (96) for transmitting data to and/or receiving data from another device of the system having a counterpart connector and a magnetic coupling unit (92), separate from the transmission unit (96), for transmitting power to and/or receiving power from another device of the system having a counterpart connector by use of inductive coupling. The battery module is configured for mobile use and for coupling with different devices of the system.

Abstract: Systems and methods for monitoring a patient with a specific condition by using a kit with monitoring devices and a corresponding memory device for the specific condition. The system comprises a health monitor, and a plurality of monitoring devices for acquiring patient health data. The kit further comprises one or more monitoring devices—such as pulse oximeters, sphygmomanometers, thermometers, EEG and ECG leads, blood 5 glucose meters, and other health monitoring devices relating to the condition specific to the kit. Such a system may be useful as a means of identifying current patient condition and determining which steps to take in the emergency situation.

Abstract: A subtraction processing unit generates a soft portion image representing a soft portion tissue of a subject from first and second radiation images. A body thickness estimation unit estimates a body thickness distribution of the subject on the basis of imaging conditions in a case where the soft portion image and the first and second radiation images are acquired. An approximate body thickness distribution calculation unit calculates an approximate body thickness distribution obtained by approximating the estimated body thickness distribution to a model corresponding to a human body, and a body fat percentage calculation unit calculates a distribution of a body fat percentage in the subject on the basis of the approximate body thickness distribution.

Abstract: Described are various embodiments of a system, device and method for monitoring physical recovery, for instance, that allow for the effective monitoring of pain, and the evolution thereof, during such recovery, in some examples, within the context of a rehabilitation or recovery training program that may involve a series of prescribed exercise routines and the like.

Abstract: An MRI antenna array including a housing and a substrate, antenna elements and circuitry encapsulated by the housing. The housing, antenna elements, and substrate are flexible to allow the housing to distort in three dimensions to closely conform to contours of a patient. The antenna elements may be formed from a flat weave mesh conductor. The flat weave mesh conductor allows the MRI antenna array to conform to the contours of a patient to provide three dimensional movement of the array. The flat weave mesh conduct has increased durability over a tight weave mesh of an elongate hollow cylinder conductor, allowing the flat weave mesh conductor to withstand additional flexing cycles.

Abstract: A binaural hearing system comprises a) left and right hearing devices, e.g. hearing aids, adapted for being worn at or in left and right ears, respectively, of a user, or for being fully or partially implanted in the head at the left and right ears, respectively, of the user, each of the left and right hearing devices comprising a1) a number NS of different sensors Si (i=1, . . . , NS), each sensor being configured to monitor a physiological function of the user and providing respective left and right sensor signals STi,left, STi,right (i=1, . . . , NS), indicative of the state of the physiological function in question; a2) electric circuitry to provide that information signals, including said sensor signals can be exchanged between the left and right hearing devices and/or forwarded to an auxiliary device, b) a comparison unit for comparing said left and right sensor signals, and providing respective comparison signals CSli (i=1, . . .

Abstract: Sensor systems are described that are designed to be integrated with gloves for the human hand. An array of sensors detects forces associated with action of a hand in the glove, and associated circuitry generates corresponding control information that may be used to control a wide variety of processes and devices.

Abstract: A rehabilitation footwear device for assisting in controlling weight application to an injured lower appendage includes a shoe that is configured to position around and reversibly couple to a foot of a user. A control module that comprises a power module and a microprocessor is coupled to the shoe. The microprocessor is operationally coupled to the power module. A plurality of sensors is coupled to and positioned in a sole of the shoe. The sensors are operationally coupled to the microprocessor. The sensors are configured to measure pressure applied to the sole from the foot that is positioned in the shoe and to relay a pressure measurement to the microprocessor. A speaker is coupled to the shoe. The speaker is operationally coupled to the microprocessor. The microprocessor is positioned to compel the speaker to emit an audio alert should the pressure measurement exceed a threshold limit.

Abstract: Systems and methods for using a smart carpet to monitor a health status of an individual. The smart carpet has electronics and a plurality of pressure sensing areas for sensing plantar pressure of the individual. A monitoring computer comprising a processor and a memory including machine readable instructions processes carpet data. A first part of the smart carpet is scanned at a first frequency and a second part of the smart carpet is scanned at a second frequency greater than the first frequency. Plantar pressures are received from the second part of the carpet and the instructions evaluate the plantar pressures to determine at least one of a physical activity and a physiological activity. Where an emergency condition is determined, an alarm is communicated to monitoring personnel.

Abstract: A motion artifact detecting method using wavelet transform which is capable of removing the problem caused by a radio noise and a motion artifact generated during the measurement of a PPG signal which is one of bio-signals, the method including: measuring a PPG signal; generating a signal obtained by removing a radio noise from the measured PPG signal; setting a reference signal from the signal from which the radio noise is removed; selecting a base signal based on the set reference signal; performing wavelet transform using the base signal; and detecting and removing a motion artifact using the wavelet-transformed value.

Abstract: In a method and a device for quantification of a respiratory sinus arrhythmia, a heart-rate curve is measured first and then the time elapsed between two heartbeats is determined and quantified by an analysis in the phase domain. A more informative quantification is obtained when suitable coefficients are used or the heart-rate curve is interpolated and/or detrended for the quantification.