Abstract: The present disclosure includes an electromagnetic field detection and monitoring system. The system includes passive detection, active detection, and signal processing capabilities. At least one embodiment includes a body worn system with sensing, processing, communications, and data storage capabilities. The system provides wearable antennas to transfer the EMF energy in its electrical or magnetic forms into the sensor efficiently. A specially designed processing algorithm can process the collected data and generated the results for medical professionals to read and make decisions.

Abstract: A method of deriving one or more individual thoracic parameters of a subject. The method comprises instructing a subject to perform a thoracic volume manipulation, receiving a plurality of measurements of a plurality of EM signals from a thoracic intrabody area of lungs of the subject during the thoracic volume manipulation, deriving a plurality of thoracic volume values at a plurality of different intervals during the thoracic volume manipulation so that each the thoracic volume value correspond with another of a plurality of estimated thoracic volumes achieved during the thoracic volume manipulation, and calculating at least one individual thoracic parameter of the subject by combining between the plurality of measurements and the plurality of thoracic volume values.

Abstract: A method and system are provided for detecting a position of a periodically moving organ in a MRI examination. MR images of an examining person including a periodically moving organ are provided over a plurality of periodic cycles of the periodically moving organ. Based on the provided MR images, a pixel frequency is associated with each pixel of the MR images. Using the associated pixel frequencies and the positions of the pixels within the MR images, the position and the frequency of the periodically moving organ are determined.

Abstract: Disclosed are a method of detecting a neuron resonance signal and an MRI signal processing apparatus. The method of detecting a neuron resonance signal includes acquiring a plurality of different digital sequences respectively corresponding to a plurality of different repetition periods by sampling a magnetic resonance signal of a neuron resonance signal according to each of the plurality of different repetition periods and calculating correlation between the plurality of different digital sequences in a frequency band based on the plurality of different digital sequences.

Abstract: A system for moving a patient into and from a medical apparatus includes a patient support arranged outside a treatment space of a medical apparatus, a treatment table arranged inside the treatment space in the medical apparatus and a patient bed movable in a longitudinal direction from the patient support to the treatment table and back by activation of a transferring mechanism. The system may further include a coil arrangement including an anterior coil and a support stand, the support stand resting on the patient bed adjacent to longitudinal edges of the patient bed and being slidable along the patient bed in a longitudinal direction when a patient is placed on the bed.

Abstract: Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.

Abstract: A target respiration rate is determined for a user where, when the user breathes at the target rate, the user's vagal tone is improved, which provides a physiological benefit to the user, e.g., stress reduction without drug intervention. The user is directed to breathe at different rates while heart rate and breathing rate are measured. A value representative of vagal tone is generated from the measured heart and breathing rates for each directed breathing rate. The breathing rate that produced the lowest generated vagal tone value is determined to be the user's target respiration rate.

Abstract: The present invention discloses an alignment device, system, and method of using the alignment device. The alignment device includes a femoral portion coupled to the femoral bone and a tibial portion mounted on the bone. A method for measuring alignment characteristics of a prosthetic knee joint arranged between a femur and tibia are disclosed. The method may include obtaining an alignment device. The alignment device may include a femoral portion, a tibial portion, and wherein at least one of the femoral portion and the tibial portion include at least one sensor. The method may also include coupling the alignment device to the femur and tibia and determining a first range of motion. The method may further include performing a knee replacement operation and determining a second range of motion.

Abstract: The invention relates to a treatment apparatus for treating a gait irregularity of a person (1). The treatment apparatus (10) comprises a gait irregularity monitoring unit (11) for detecting a gait irregularity of the person, (a) cueing unit(s) (15, 16, 17), and a cueing control unit (14) for controlling the cueing unit(s) to provide, in response to the detection of the gait irregularity, a first cue set for treating the gait irregularity to the person. The gait irregularity monitoring unit monitors the effect of the providing of the first cue set to the person and determines whether the detected gait irregularity is being overcome. The cueing control unit controls the cueing unit(s) to provide a different second cue set to the person, if it has been determined that the detected gait irregularity has not been overcome. This improves the likelihood of being able to effectively treat the detected gait irregularity.

Abstract: A method and apparatus for monitoring arterial properties, including systolic and diastolic pressure levels, of a subject is provided, in which a hardware processor receives and analyzes ballistocardiogram (BCG) data of the subject. A non-transient computer readable medium, accessible by the hardware processor, contains instructions that, when executed by the hardware processor, identify features of the BCG waveform and determine the arterial properties therefrom. For example, a diastolic pressure level may be determined from a time interval between the ‘I’ and ‘J’ peaks of the waveform and a systolic pressure level determined from the amplitude difference between the ‘J’ and ‘K’ peaks of the waveform in combination with the ‘I-J’ time interval or amplitude difference. A physical mechanism for the BCG data is disclosed that enables other arterial properties of the subject to be determined from the BCG data alone or from the BCG data in combination with other measurements.

Abstract: A method and wireless sensor device for determining body postures and activities. In one aspect, a method includes receiving sensor data. The method also includes detecting and classifying a body transition of a body based on the sensor data. The method also includes detecting if there is activity of the body based on the sensor data. If there is activity, the method also includes classifying the activity. If there is no activity, the method also includes classifying a rest position of the body based on the sensor data and based on a previous body transition.

Abstract: The present disclosure aims to provide an evaluation apparatus and an evaluation method capable of evaluating a walking assistance apparatus by simulating an actual person's walking motion. An evaluation apparatus 1 includes a placement part 5 on which a sole part of a walking assistance apparatus 4 to be evaluated is placed; an actuator 3 configured to apply a load to the walking assistance apparatus 4 in a direction of the placement part 5 in a state in which the sole part faces the placement part 5; and an actuator 6 configured to change a relative positional relation between the placement part 5 and the sole part.

Abstract: Systems and methods allow for evaluating health conditions based on fingerprints and other skin patterns. A smartphone or other personal electronic device captures patient scans, such as fingerprint patterns transmitted from a wireless fingerprint scanner. Scans can be transmitted to a network-connected server for storage and analysis. The nature, frequency and location of patterns are compared to known correlations to generate a condition output. The condition output may then be made available to a patient and/or a medical professional, such as via notification message and/or access to a web portal.

Abstract: Methods and kits for determining a propensity to develop Type 1 diabetes mellitus (T1DM) and for Type 2 diabetes mellitus (T2DM) in an individual by measuring an asymmetry of at least one captured fingerprint from the individual are described.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

Abstract: Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Abstract: An analyte monitoring system comprising: an on-body housing; an analyte sensor coupled to the housing; an electrical output interface disposed on an outer surface of the housing; and a removable adaptor coupled to the housing. In one embodiment, a portion of the analyte sensor extends from the housing for implantation into a patient's body. The electrical output interface is electrically coupled to the analyte sensor. The removable adaptor is mechanically coupled to the housing and electrically coupled to the electrical output interface. The removable adaptor serves as a data conduit between the analyte sensor and a remote device.

Abstract: The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.

Abstract: A system for monitoring glucose blood level of a user is disclosed. The system comprising an illumination unit configured for providing coherent optical illumination on a selected inspection region on the user body, a collection unit configured for collecting light returning from the inspection region and generating a plurality of image data pieces associated with speckle patterns in the collected light, and a control unit comprising a processing utility and storage utility comprising pre-stored calibration data, the processing utility is configured for receiving input data on a plurality of image data pieces from the collection unit and for processing said input data for determining correlation functions between different image data pieces and using said correlation functions and said pre-stored calibration data for determining data on glucose blood level of the user.

Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.

Abstract: A sensing device, designed to be used in contact with the skin, contains a plurality of individually controllable sites for electrochemically monitoring an analyte, such as glucose, in interstitial fluid of a user. The device includes at least a hydrophobic layer designed to contact the skin; a capillary channel providing an opening adjacent the skin; a metal electrode layer having a sensor layer applied to an edge portion thereof such that it is exposed to the interior of said capillary channel, the sensing layer being effective to measure the analyte.

Abstract: The biological information detection sensor supply device is provided with a main body case having a supply port to which a biological information measurement device can be attached, a housing unit for housing a biological information detection sensor and a sensor supply film including a cover film and a holding film for sandwiching the biological information detection sensor, and a supply unit for supplying the biological information detection sensor from the housing unit to the supply port. The supply unit supplies the biological information detection sensor to the supply port, and separates the holding film and the cover film from the sensor supply film in a state before the biological information detection sensor is supplied to the supply port. At the supply unit, the biological information detection sensor supplied to the supply port is fitted to the biological information measurement device fitted to the supply port.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.

Abstract: A portable medical storage unit (station) is configured in the form of a phlebotomy arm wedge that includes internal storage along with other optional features to facilitate a health professional to perform a phlebotomy. The portable medical storage unit thus provides an alternative product to a phlebotomy chair and has a much smaller footprint and can easily be stored in closet or the like. Moreover, the portable medical storage unit can be made at much less cost than a phlebotomy chair.

Abstract: Inside a connector body (112, 114; 300) of a medical connector providing a fluid flow conduit, a one-way valve (118) is fitted directly into one end of a stop valve (116) in a manner providing a fluid tight seal between these valves. The stop valve (116) prevents fluid flowing out of the end (111; 311) of the connector body (112, 114; 300) unless a complementary end of a separate device (not shown), typically a Luer lock connector, engages the end of the connector body and opens the stop valve (116). To facilitate manufacture and assembly, the one-way valve (118) and the stop valve (116) can be formed as parts of a single piece of elastomeric material, the parts being hingedly connected so that the one-way valve part (118) can be folded over to be fitted directly into the end of the stop valve part (116). A further possibility, also applicable when only a stop valve (116) is provided, is that the connector body (300) may be formed in one piece with a folding, snap fit closure (312).

Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.

Abstract: A method, apparatus and computer program product are provided for determining stress recovery based on chest and abdominal breathing information from a detection device such as a radar detection device. Stress recovery may be determined by monitoring a phase difference between chest and abdominal breathing relative to a stress indicator, such as heart rate variability. Target respiration information may be determined and/or calibrated for the particular user based on the stress indicator. Breathing exercises may be provided to the user to assist in steadying their breathing and recovering from stress. Based on the monitoring of the chest and abdominal breathing information, efficacy of the breathing exercise may then be determined based on whether the user is recovering from stress, and further feedback may be provided to the user.

Abstract: The invention is an ex vivo method for early detection of acute kidney injury in critical patients, which includes the measurements of fibroblast growth factor 23 (FGF23), klotho (KL) and erythropoietin (EPO) as biomarkers. These measurements are obtained from a venous blood sample or urine, and allow the determination of the following indicators: 1=([FGF23]p×[EPO]p); 2=([FGF23]p/[Klotho]p); 3=([EPO]p)/[Klotho]p); 4=([FGF23]p×[EPO]p)/[Klotho]p); where [X]p is defined as the plasma level of a specific molecule (X) which includes fibroblast growth factor 23 (FGF23), klotho (KL) or erythropoietin (EPO). If the value of the indicator 1, 2, 3, 4 or two or more thereof, is equal or higher than a cut-off point (10 U), the indicator and/or indicators allow the identification of patients with high risk of developing AKI, with a high sensitivity/specificity.

Abstract: A measurement chamber that is essentially dome-shaped and has a base area with a membrane and has at least two connectionpoints fora fluid flow. The measurement chamber has two outer webs opposite each other, one of the webs engaging a clamping edge of a coupling element.

Abstract: System, method and media for quantifying bulbar function of a subject. At a high level, embodiments of the invention measure and quantify bulbar function of a test subject based on video data, audio data, or other sensor data of a subject performing a test of bulbar function, such as speech, swallowing, and orofacial movements. This sensor data is then analyzed to identify key events such as syllable enunciations. Based on one or more characteristics of these key events (such as, for example, their rate, count, assessed accuracy, or trends over time), the bulbar function of the subject can accurately, reliably, and objectively be quantified.

Abstract: A system for inhibiting shaking includes a plurality of parallel tracks each to join a plurality of mini gyroscopes in series, the parallel tracks joined at one or more control junctures and disposed on a flexible substrate wrap. The system also includes a plurality of mini gyroscopes spaced apart in series by each of the plurality of parallel tracks, the mini gyroscopes to spin about an axis relative to a single parallel track at a variable angular momentum. The system additionally includes a plurality of accelerometers to differentiate shaking and purposeful movement of portions of the flexible substrate wrap and provide output thereof and feedback on shaking ablation. The system further includes a controller to control the variable angular momentum and the spin axis of the mini gyroscopes to ablate shaking relative to purposeful movement of portions of the substrate wrap based on accelerometer output.

Abstract: A method of monitoring a patient for seizure activity may include monitoring the patient by collecting an electromyography signal, determining features of the signal using wavelet analysis and inputting determined feature values into a neural network trained to detect seizure activity. Related apparatuses are also described.

Abstract: A device is described, which is fully implantable and records the EEG of a person, where the device comprises a subcranial probe containing one or more electrodes, and an extracranial portion, which includes at least one electrode. The subcranial probe proceeds through an opening in the skull. The intracranial portion comprises a seal, which prevents fluid ingress or egress between the subcranial portion and the extracranial portion. Due to the high electrical resistance of the skull, the seal effectively isolates the extracranial electrode from the intracranial electrodes, making the extracranial electrode an effective ground reference for EEG recording.

Abstract: A medical workstation is defined by a supporting structure having at least one medical diagnostic instrument disposed thereupon. A first display is further disposed on a first side of the supporting structure and a second display is disposed on a second side of the supporting structure in a manner substantially opposite from the first display. Each of the first and second displays are interconnected to the at least one medical diagnostic instrument to permit at least one of the displays in order to display diagnostic results and are tandemly or independently controllable.

Abstract: Multi-modal sensing relating to joint acoustic emission and joint bioimpedance. Custom-design analog electronics and electrodes provide high resolution sensing of bioimpedance, microphones and their front-end electronics for capturing sound signals from the joints, rate sensors for identifying joint motions (linear and rotational), and a processor unit for interpretation of the signals. These components are packed into a wearable form factor, which also encapsulates the hardware required to minimize the negative effects of motion artifacts on the signals.

Abstract: A system, method and apparatus is disclosed, comprising a biomathetical model for optimizing cognitive performance in the face of sleep deprivation that integrates novel and nonobvious biomathematical models for quantifying performance impairment for both chronic sleep restriction and total sleep deprivation; the dose-dependent effects of caffeine on human vigilance; and the pheonotypical response of a particular user to caffeine dosing, chronic sleep restriction and total sleep deprivation in user-friendly software application which itself may be part of a networked system.

Abstract: A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity.

Abstract: A method and apparatus for the treatment of Sleep Apnea events and Hypopnea episodes wherein one embodiment comprises a wearable, belt like apparatus containing a microphone and a plethysmograph. The microphone and plethysmograph generate signals that are representative of physiological aspects of respiration, and the signals are transferred to an imbedded computer. The embedded computer extracts the sound of breathing and the sound of the heart beat by Digital Signal Processing techniques. The embedded computer has elements for determining when respiration parameters falls out of defined boundaries for said respiration parameters. This exemplary method provides real-time detection of the onset of a Sleep Apnea event or Hypopnea episode and supplies stimulation signals upon the determination of a Sleep Apnea event or Hypopnea episode to initiate an inhalation. In one embodiment, the stimulus is applied to the patient by a cutaneous rumble effects actuator and/or audio effects broadcasting.

Abstract: Various methods and machines have been used in the past to measure electrical characteristics of living tissue for purpose of locating an area of abnormal nervous system activity. However, whereas prior art methodologies merely allow for the detection of pain, the apparatus, system and method of the present invention allow for the objective assessment pain severity that finds utility not only the initial diagnosis but also the on-going treatment of any disease, disorder or injury associated therewith. To that end, the apparatus, system and method of the present invention allows medical practitioners to non-invasively and quantitatively distinguish organic pain from psychosomatic pain and legitimate pain patients from drug seekers and opiod addicts, as well as to directly and objectively compare the efficacy of different drug regimens and therapy protocols.

Abstract: Embodiments of the present systems and methods may relate to a non-invasive system with diagnostic and treatment capacities that use a unified code that is intrinsic to physiological brain function. For example, in an embodiment, a computer-implemented method for affecting living neural tissue may comprise receiving at least one signal from at least one read modality, the signal representing release of photons from mitochondria of the living neural tissue, computing at least one signal to effect alterations to the living neural tissue based on the received input signal, the computed signal adapted to cause transmission of photons to the living neural tissue, and delivering the photons to the living neural tissue to effect alterations to the living tissue.

Abstract: In embodiments, devices, methods and systems to analyze the different mediums of brain function in a mathematically uniform manner may be provided. These devices, methods and systems may manifest at several levels and ways relating to brain physiology, including neuronal activity, molecular chirality and frequency oscillations. For example, in an embodiment, a computer-implemented method for determining structure of living neural tissue may comprise receiving at least one signal from at least one read modality, the signal representing at least one physical condition of the living neural tissue, determining action potentials based on the signals received from the read modalities, determining frequency oscillations based on the signals received from the read modalities and the action potentials, and determining neuron network structures based on the signals received from the read modalities, the action potentials, and the frequency oscillations.

Abstract: A catheter system for controlled sympathectomy procedures is disclosed. A catheter system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed.

Abstract: A method and system for monitoring a user's intoxication including receiving a set of signals, derived from a set of samples collected from the user at a set of time points; providing a sobriety task to the user proximal to a time point of the set of time points; generating a performance dataset characterizing performance of the sobriety task by the user; receiving a supplementary dataset characterizing a demographic profile of the user and/or a physiological state of the user; determining a set of values of an intoxication metric, derived from the set of signals; generating a predicted temporal profile of the intoxication metric for the user based upon the set of values, the set of time points, and the supplementary dataset; generating an analysis of the user's sobriety based upon the performance dataset and the predicted temporal profile; and providing a notification to the user based upon the analysis.

Abstract: A sensor for indirect estimation of breast milk intake by an infant, the sensor comprising: a housing configured to be externally attached to an incontinence product worn by a subject, said housing comprising: a light-emitting diode (LED) configured to illuminate the incontinence product; a photodetector configured to output an indication of the amount of light reflected from the incontinence product; and an integrated circuit configured to: (a) receive the indication from said photodetector, (b) compute, based on the indication, an amount of urine secreted by the subject into the incontinence product, and (c) estimate the amount of breast milk intake by the infant based on the amount of urine secreted by the subject into the incontinence product.

Abstract: For tissue property estimation with ultrasound, multiple different types of measurements are performed by an ultrasound system, including scatter measurements and shear wave propagation measurements. The tissue property, such as liver fat fraction, is estimated using a combination of these different types of measurements.

Abstract: Provided herein is a method for automatic assessment of squat quality using a quantitative measure of a mobility test, such as a single leg squat (SLS) performance. The method is useful in clinical assessment protocols for rehabilitation, sports medicine, and orthopedic knee surgery assessment.

Abstract: A monitoring device for measuring one or more physiological parameters of a medical patient can include a finger clip sensor connected to a monitor. A placement indicator helps the patient to properly position the sensor. The monitor can display a message alerting the patient to reposition the sensor. The device can delay measurement until the sensor is properly positioned.

Abstract: An ocular device is disclosed along with methods for the employment thereof. In one aspect, a device for placement into a lacrimal punctum or conjunctival sac of a person includes one or more sensor materials responsive to one or more components of the chemical composition of the person's tears. Each sensor material is configured to present a tear-based color from a plurality of tear-based colors indicative of a medical condition of the person. In some embodiments, phenylboronic acid could be employed as a sensor material(s). In some embodiments, material(s) emitting radiation when excited by other radiation could be employed as a sensor material. In another aspect, methods for employing the ocular device are disclosed.

Abstract: An electrode assembly includes a first surface to be placed adjacent a person's skin and a second surface including a plurality of reservoirs of conductive gel. The plurality of reservoirs of conductive gel are disposed on sections of the electrode assembly that are at least partially physically separated and may move at least partially independently of one another to conform to contours of a body of a patient. The electrode assembly is configured to dispense an amount of the electrically conductive gel onto the first surface in response to an activation signal and to provide for a defibrillating shock to be applied to the patient through the amount of the electrically conductive gel.

Abstract: A biophotonic measurement device characterized by having: one or a plurality of photoirradiation means; one or a plurality of light detecting means; a mounting means for mounting the photoirradiation means and the light detecting means to a subject; an analysis means for calculating a state of mounting of the photoirradiation means and the light detecting means to the subject on the basis of a detection value measured by the light detecting means; and an output means for outputting the state of mounting using light or a voice, the output means being installed on the mounting means mounted to the subject, the photoirradiation means, or the light detecting means.