Abstract: An apparatus includes a tubular structure having a proximal end, a distal end, and a body extending between the proximal and distal ends, wherein the body includes a lumen for housing at least a part of an imaging device, and a fluid delivery channel that is fixed in position relative to the body, and an opening that is in fluid communication with the fluid delivery channel, wherein the fluid delivery channel has a first portion, and a second portion that forms an angle with an axis of the first portion.

Abstract: Bronchoscope adapters and methods of using the same are provided. Aspects of the adaptors include a body having a passageway, a mechanical ventilator access port, a bronchoscope access port configured to receive a bronchoscope into the passageway, and an exit port. The bronchoscope access port comprises a reversibly adjustable inner diameter component that provides locking of the bronchoscope at desired position. The adaptors find use in a variety of different applications.

Abstract: It is described an endoscope to perform surgeries preferably by perforation in translumenal organs in internal organs, comprising an insertion tube (10?) having a distal end (12?) and at least two working channels, one working channel having a smaller diameter (20?) and one working channel having a larger diameter (30?), the working channels (20?,30?) being capable of receiving surgical tools, the endoscope comprising at least two command cables (9?) operatively associated with the working channel of smaller diameter (20?) and at least two command cables (9?) operatively associated with the working channel of larger diameter (30?), the command cables (9?) being capable of allowing the surgical tool, arranged on any of the working channels (20?,30?), to move in any direction, regardless of the movement of the distal end (12?) of the insertion tube (10?).

Abstract: An endoscope includes an insertion portion that includes a distal end portion and a bending portion configured to change a direction of the distal end portion . The distal end portion includes a casing having a round shape in a cross-section, and an image pickup module that includes an optical module section including a plurality of optical members and an image pickup section, the image pickup module having a rectangular shape in a cross-section, and the image pickup section includes an image pickup device and a semiconductor stack in which a plurality of semiconductor devices is stacked, and entirety of the image pickup module is completely housed inside the casing.

Abstract: An illumination light guiding device includes a phosphor layer that is disposed on another surface opposite to one surface of a board, and converts the wavelengths of a plurality of light beams transmitted through the board and incident on one surface of the phosphor layer, and an emission-side fiber including a plurality of optical fibers that are provided so as to be erected side by side on another surface opposite to one surface of the phosphor layer, each optical fiber guiding a different one of the plurality of light beams having wavelengths converted by the phosphor layer.

Abstract: An optical probe for use in medical instrumentation where a sheath is covering the optical probe, wherein the optical probe is configured to correct astigmatism by incorporating asymmetric optical powers.

Abstract: A method of operating an anatomical probe system comprises providing an elongated flexible body including a channel and providing an operational component extending within the channel of the flexible body. The method also comprises providing a support member at a distal end of the flexible body. The support member includes a fluid director. The method also includes conveying fluid through the channel and into contact with the fluid director to direct the fluid toward the operational component.

Abstract: A medical diagnostic instrument or a plurality of disparate medical diagnostic instruments are configured with a common optical architecture that functionally creates a virtual eye to create closer proximity to a patient and therefore increase the field of view in regard to a target of interest. The optical system includes a distal optical element, at least one relay lens and an eyepiece lens in which the optical system can be integrated within at least one instrument or be provided using a releasable module. Additionally, at least one of a viewing assembly and illumination assembly of at least one medical diagnostic instrument can be assembled using a series of components that are connected by interlocking features.

Abstract: The invention relates to an image-recording device (10), comprising a scanning-head guide (18) for moving the scanning head (20) across a scanning region (42) of a cavity, which scanning region (42) extends around the scanning head (20). A planar or film-like, elastically extensible material extends between the scanning head (20) and the scanning region (42), which material can be pressed against the scanning region (42) by the application of overpressure in the manner of a balloon (12). The scanning-head guide (18) extends through the balloon connection (16) of the balloon (12) to the scanning head (20). In particular, a control device (32) determines the shape of the cavity (40) against which the material rests from the deformation of the material while the overpressure is present.

Abstract: An imaging device including a support, a dental retractor fastened to the support and defining a retractor opening, a mirror fastened to at least one of the support and the retractor, and structure for fastening an image acquisition apparatus to the support in a position in which the acquisition apparatus is oriented so as to receive a composite image including a direct image of the retractor opening and an image of the retractor opening reflected by the mirror.

Abstract: Disclosed are devices for cardioscopic and pericardioscopic access to the heart, including direct access to the left atrium. In certain embodiments, the device may comprise an atrial portal having a configuration such that the distal end of the atrial portal can access the atrium while the proximal end of the portal can extend to outside of the subject. The devices and methods may also include a pericardioscopic portal for emplacement of the atrial portal. Also, methods for using such atrial portals and pericardial portals to perform surgery on the heart, and in some cases to directly access the left atrium, and systems (e.g., kits) comprising these portals in combination with other therapeutic devices are disclosed.

Abstract: An optical measurement apparatus for an eyeball includes a light emitter, a light receiver, a detector, and a controller. The light emitter emits light such that the light passes across an eyeball of a subject. The light receiver receives the light that has transmitted through the eyeball. The detector detects a direction of the eyeball. The controller performs control such that the light emitter starts emitting light having an intensity used in measurement or the light emitter increases an intensity of light emitted by the light emitter to the intensity used in measurement in a case where the direction of the eyeball detected by the detector is in a predetermined range.

Abstract: An ophthalmic imaging apparatus according to an exemplary embodiment includes a three dimensional data generator, an analyzer, and a display controller. The three dimensional data generator generates three dimensional data by scanning a three dimensional region of a subject's eye using optical coherence tomography (OCT). The analyzer generates a plurality of analysis maps by analyzing a plurality of pieces of partial three dimensional data in the three dimensional data. The display controller displays the plurality of analysis maps over a front image of the subject's eye on a display device.

Abstract: An eye examination device including eye examination optics for examining a patient's eyes. A chin rest assembly accepts the patient's head and maintains the patient's head in a fixed stable position. The chin rest assembly can comprise two spaced apart upright posts for securing to a table, with a forehead rest member being secured to the two upright posts at an upper end, and a chin rest member being secured to the two upright posts below the forehead rest member. The chin rest member can have a chin rest portion which extends forwardly relative to an upright plane extending between centers of the two upright posts and away from the eye examination optics, so that generally only a front of the patient's face coincides with the upright plane when the patient's head engages the chin rest portion.

Abstract: Disclosed is a method for determining at least one visual behavior parameter of a person. The method includes the following steps: a step of encouraging the person to perform a visual test during which he observes at least one target position, a step of measuring an item of data that is representative of at least one viewing direction of the person during the visual test, a step of determining a reference viewing direction on the basis of the representative data measured, and a step of positioning, relative to the reference viewing direction, at least one measured target position that is determined, in a reference marker associated with the head of the person, on the basis of the data that is representative of the viewing direction of the person measured during the visual test.

Abstract: A confocal laser fundus angiographic device, comprises: an objective lens, a scanning lens, a scanning galvanometer, a mirror, a filtering module, an imaging detection assembly and an excitation light source. The illumination light emitted by the excitation light source enters the fundus passing through the scanning galvanometer, the scanning lens and the objective lens. Fluorescent substances in fundus vessels are excited by the illumination light and emit light with a specific wavelength. The light with a specific wavelength enters the imaging detection assembly by passing through the objective lens, the scanning lens, the scanning galvanometer, the mirror and the filtering module. The filtering module comprises a base, a motor mounted on the base, a rotary block mounted on the motor and at least one filter mounted on the rotary block. The base is provided with a light-through hole.

Abstract: The invention relates to a device for measuring the speed of blood in a blood vessel of the eye. Said device includes: a light source (5), two detectors provided with input diaphragms (36, 46) for receiving two light beams backscattered by a blood vessel, an optical system including a Dove prism (70) through which the source beam and backscattered beams pass and which is rotatably adjustable about an axis parallel to the source beam passing therethrough, and a focusing system (62) capable of forming the image of a blood vessel on the input diaphragms, a processor capable of processing the signals from the detectors, and an opitcal element (52) that can be inserted during the device adjustment phase so as to convert the light spot, provided by the light source, into a line coplanar with the source beam and the backscattered beams.

Abstract: An ophthalmological imaging device comprising an objective lens, an interference optical system, an image forming unit, an optical member, and an analyzer. The interference optical system divides light from a light source into measurement light and reference light, causes the measurement light to become incident on a subject's eye via the objective lens, and detects interference light between the reference light and return light of the measurement light that has exited from the subject's eye and passed through the objective lens. The image forming unit forms an image of the subject's eye based on a detection result of the interference light which are acquired by the interference optical system. The analyzer analyzes a first detection result and a second detection result of the interference light to eliminate noise in the second detection result or in an image based on the second detection result.

Abstract: The invention relates to a physiological parameter monitoring device (100) comprising a first contact lens element (102) having an inner surface (103) and an outer surface (104) opposite the inner surface (103), a second contact lens element (110) having an inner surface (111) and an outer surface (112) opposite the inner surface (111), wherein the first contact lens element (102) and the second contact lens element (110) are attached to one another at a peripheral attachment area (109), thereby enclosing an intermediate space (105), and further comprising a passive sensing means (101) forming a resonant circuit for detecting variations of said physiological parameter, wherein the passive sensing means (101) is provided only in or on the first contact lens element (102).

Abstract: Ophthalmological device including an applanation tonometer tip having a bi-curved cornea-contacting surface structured to minimize the intracorneal stress, and method of using such device for measurement of intraocular pressure. The cornea-contacting surface includes a first central portion and a second portion that encircles and adjoins the first central portion. The curvatures of the first and second portions have opposite signs. In one case, the first central portion can be rotationally-symmetric. In a related case, the first portion has a curvature with a sign opposite to that of a curvature of a typical cornea, while the curvature of the second portion has a sign equal to that of the curvature of the cornea. Method for using the device to procure values IOP with increased ac curacy as compared with the use of a conventional flat-surface tonometer tip.

Abstract: In some implementations, an apparatus includes a first microprocessor, a digital infrared sensor operably coupled to the first microprocessor, an ambient temperature sensor operably coupled to the first microprocessor, a battery operably coupled to the first microprocessor, a multi-vital-sign finger cuff that is detachable and removable from the apparatus and that includes: a printed circuit board, a SpO2 subsystem that is operably coupled to the printed circuit board and that includes a photoplethysmogram sensor and that is operably coupled to the printed circuit board, the photoplethysmogram sensor includes one infrared detector that detects infrared energy at two different transmitted wavelengths, red and near infrared, and a micro dynamic light scattering sensor, the micro dynamic light scattering sensor includes two photo diode receivers and one laser transmitter.

Abstract: A system for measuring physiological parameters, including: a portable measurement system, operable to acquire physiological measurement from an examined body location; an external camera operable to capture visible light, oriented toward the examined body location; a synchronization module, operable to receive a triggering indication, and in response to the triggering indication to associate to the physiological measurement a positioning image captured by the camera, the positioning image including at least a part of the portable measurement system adjacent to the examined body location; and a communication module operable to obtain the physiological measurement and the positioning image, and to transmit to a remote system: a physiological measurement record based on the physiological measurement, an orientation image based on the positioning image, and including at least a part of the portable measurement system adjacent to the examined body location, and association data associating the orientation image a

Abstract: The present invention is a method, system, and apparatus used to transmit information to an individual and or receiver who is not located at the actual ultrasound procedure that may monitor, communicate, and assist in the procedure in real time as well as provide protocols for specific procedures; wherein the ultrasound machine communicates to a receiver operational information such as but not limited to audio, visual, performance, and so forth; wherein the information may be received in real time to another party not located at the site of the procedure who may assist with the procedure, training, protocols, and so forth; and wherein the receiver may then transmit back to the ultrasound machine specific directions as well as communicate with the ultrasound operator.

Abstract: Various embodiments provide a cardiac imaging system and method that includes using a portable electrocardiogram (ECG) recorder to record ECG data of a patient having an episodic cardiac condition for a time period sufficient for symptoms of the episodic cardiac condition to occur. The recorded ECG data may be provided to a processing unit along with other patient data. The processing unit may generate a three-dimensional (3D) activation map showing the propagation of electrical signals through the patient's heart. Based on the provided patient data, the processing unit may display an ablation point on the 3D activation map, the ablation point being configured to alleviate the episodic cardiac condition.

Abstract: A vehicle configured for conveying at least one container. The vehicle has a supporting portion configured for holding said container, and a primary lifting mechanism for controlling elevation of the supporting portion. The lifting mechanism is configured to move the supporting portion between an elevated position and a lowered position. The supporting portion is configured for assuming a retracted state associated with a first outline of the vehicle when seen from above, and combinable at least with the lowered position of the supporting portion, and an extended state associated with a second outline of the vehicle when seen from above and combinable at least with the elevated position of the supporting portion. The supporting portion in its extended state has projecting areas, projecting in the second outline relative to the first outline and configured for supporting said container.

Abstract: Systems and methods for biocompatible tissue characterization using Raman imaging are provided. The systems and methods utilize Raman systems tuned to monitor spectral wavelengths characteristic of target types of tissue to monitor constituents of that tissue in biological systems and samples. The Raman systems may be tuned to monitor the Raman signature for the formation of the chemical bonds that join phosphorous and oxygen (PO) atoms, such that the formation of hydroxyapatite may be monitored and used to determine the presence of bone formation in a sample, such as, for example, biological tissue.

Abstract: Methods and apparatus for identifying microbiological constituents in the middle ear. A spectrometer receives Raman-scattered light from the region of the tympanic membrane and resolves spectral features of the Raman-scattered light. A processor receives the interferometry signal and the Raman signal, and generates a Raman spectrum of the tympanic membrane and material adjacent thereto. In some embodiments of the invention, low-coherence light and substantially monochromatic excitation light are directed onto a tympanic membrane of the ear of a person via an otoscopic tip that abuts the ear canal. An interferometer combines scattered low-coherence light from the ear tissue with a reference signal to generate an interferometric signal.

Abstract: A system for providing multi-wavelength laser includes an optical splitter arranged to split light received from a pulsed laser source into at least a first light beam and a second light beam; a first optical regulator arranged to adjust a wavelength of the first light beam and to output the adjusted first light beam; a second optical regulator arranged to introduce a time delay to the second light beam and to output the delayed second light beam; and an optical combiner arranged to combine the first adjusted light beam and the second delayed light beam, and to output a combined light beam.

Abstract: An estimation device includes at least one of a facial skin temperature acquisition unit and a facial photographic image acquisition unit, and an evaluation unit. The facial skin temperature acquisition unit acquires, in time-series, facial skin temperature data of a facial surface of a subject to which brain function activation information is provided. The facial photographic image acquisition unit obtains, in time-series, facial photographic image data obtained by imaging the facial surface of the subject to which the brain function activation information is provided. The evaluation unit evaluates a degree of interest of the subject based on at least one of the facial skin temperature data acquired by the facial skin temperature acquisition unit and the facial surface photographic image data acquired by the facial surface photographic image data acquisition unit.

Abstract: A system includes an imaging device that captures multichannel image data from a region of interest on a patient, one or more processors, and memory storing instructions. The memory storing instructions cause the one or more processors to receive the multichannel image data from the imaging device, such that the multichannel image data includes an image signal representative of plethysmographic waveform data for the region of interest and specular noise in the multichannel image data. Furthermore, the memory storing instructions cause the one or more processors to generate a projection matrix associated with the multichannel image data and iterate values of the projection matrix to remove the specular noise to generate a representative physiological signal, such that the representative physiological signal has an improved signal-to-noise ratio relative to the image signal and the representative physiological signal is a representative plethysmographic waveform.

Abstract: The present invention discloses a microcirculation shock monitor enabling rapid and repeated positioning, a monitoring system and a monitoring method, belonging to the technical field of microcirculation shock monitoring. By the present invention, the same blood vessel in the same monitored area can be repeatedly positioned and monitored quickly within different periods of time, and blood vessel image data can be acquired, and then, on this basis, qualitative analysis or quantitative analysis is performed to obtain related monitored data, where quantitative analysis parameters comprise a high-speed blood flow intensity ratio R, a high-speed blood flow spreading rate S, a high-speed blood flow intensity duration T and a difference D of abnormal change in high-speed blood flow intensity of a monitored object, which facilitates studies and lays an accurate data foundation for rapidly indicating early and middle stage indications of infectious shock in a next step.

Abstract: Methods, systems, and storage media relating to a circulatory health monitor device are disclosed herein. In an embodiment, such a device may be positioned or disposed on and/or in contact with a subject to measure blood pressure and/or heart rate. The device may include one or more electrocardiographic (ECG) signal sensors, one or more photoplethysmographic (PPG) sensors, and a controller. The controller may activate at a low resolution a PPG measurement of the subject in relation to an ECG signal feature to identify a PPG signal feature location or region in the PPG measurement. The controller may further activate at a high resolution PPG measurement of the subject at the PPG signal feature region to identify the PPG signal feature, and may determine blood pressure and/or heart rate therefrom. Other embodiments may be disclosed and/or claimed.

Abstract: The present application discloses an apparatus for determining a blood pressure of a subject, the apparatus includes a sensor assembly configured to measure a pulse wave signal of the subject; and a signal processor configured to generate a metric of the pulse wave signal based on the pulse wave signal, to select a blood pressure calculation algorithm base on the metric of the pulse wave signal, and to determine the blood pressure of the subject using the blood pressure calculation algorithm.

Abstract: The invention provides a system and method for measuring vital signs (e.g. SYS, DIA, SpO2, heart rate, and respiratory rate) and motion (e.g. activity level, posture, degree of motion, and arm height) from a patient. The system features: first and second sensors configured to independently generate time-dependent waveforms indicative of one or more contractile properties of the patient's heart; and a cuff-based oscillometric module. A processing component, typically worn on the patient's body and featuring a microprocessor, receives the time-dependent waveforms generated by the different sensors and processes them to determine patient-specific calibration values for use in a continuous blood pressure measurement based on pulse wave velocity (PWV).

Abstract: A system can include a wearable device that obtains real-time physiological data and activity data from a user and transmits that data to another device. A computing device can receive HRV and activity data and determine whether the user's autonomic nervous system is in a predominantly sympathetic or parasympathetic state. For example, the determination can include comparing an average variance in a portion of the HRV data with a threshold value. In response to determining that the user's autonomic nervous system is in a sympathetic state, the device can perform an action.

Abstract: A system can include a wearable device that obtains real-time physiological data and activity data from a user and transmits that data to another device. A computing device can receive the data and calculate a first HRV score for the user based on physiological data from first time period and a second HRV score for the user based physiological data from a second time period. The device can present the user with at least one of the first and second HRV scores. In one example, a graphical display is provided on a GUI that includes indicators for each day of the week. In response to a user selecting an indicator for a day of the week, the GUI can display an HRV score for the selected day, among other information.

Abstract: PPG sensor emits light at at least three wavelengths (Y1-Y3) and detects the reflected light. The PPG sensor comprises a motion correction unit (130) for correcting motion artefacts from the detected light signals by subtracting the output signal of the detected light at the second wavelength (Y2) from an average of an output signal of the detected light at the first and third wavelength (Y1, Y3). The three wavelengths (Y1-Y3) are arranged around 550 nm. The second wavelength (Y2) is arranged equal distantly between the first and third wavelength.

Abstract: An optical sensor that captures a heart rate and/or a blood oxygen content includes a light source including a light emittor that emits electromagnetic radiation with a first wavelength range including green light, a second wavelength range including red light and a third wave-length range including infrared radiation, and three light detectors, each including a filter for electromagnetic radiation, wherein a first filter is transmissive for light of the first wavelength range and non-transmissive for light of the second wavelength range and the infrared radiation of the third wavelength range, a second filter is transmissive for light of the second wavelength range and non-transmissive for light of the first wavelength range and the infrared radiation of the third wavelength range and a third filter is transmissive for the infrared radiation of the third wavelength range and non-transmissive for light of the first and the second wavelength range.

Abstract: The present disclosure uses physiological data, ECG signals as an example, to evaluate cardiac structure and function in mammals. Two approaches are presented, e.g., a model-based analysis and a space-time analysis. The first method uses a modified Matching Pursuit (MMP) algorithm to find a noiseless model of the ECG data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to image and characterize cardiovascular tissues using complex-sub-harmonic-frequencies (CSF) quasi-periodic and other mathematical methods. In the second method, space-time domain is divided into a number of regions, the density of the ECG signal is computed in each region and inputted into a learning algorithm to image and characterize the tissues.

Abstract: A catheter adapted or high density mapping and/or ablation of tissue surface has a distal electrode array with offset spine loops, each spine loop having at least a pair of linear portions and a distal portion connecting the pair of linear portions, and one or more electrodes on each linear portion. The linear portions of the plurality of offset spine loops are arranged in-plane a single common plane, and the distal portions of the plurality of offset spine loops are arranged off-plane from the single common plane.

Abstract: Embodiments provide a method and system for using a reconstructed or virtual reference point for electrocardiogram (ECG) measurements, allowing for the removal of the common reference point required in conventional ECG systems. Embodiments allow for either referencing measurements back to a reference previously digitized and reconstructed in the analog domain or to compare the measurements to a virtual reference. These calculations can be performed at the measurement site or remotely. Vector calculations can be made in either the analog or digital domains. A secondary means of measuring common mode noise (or rejection) injected into the ECG may be provided to ensure proper functioning in the presence of large common mode noise. These secondary measurements may be used to phase-align segments of the ECG vectors or as means to improve the common mode noise capabilities.

Abstract: The present invention pertains to methods for monitoring and evaluating a patient's heart muscle function. For the present invention this requires simultaneously detecting both cardiac signals (i.e. an EKG) and perturbation signals caused by the environmental and physical factors that are influencing the patient. In particular, when a cardiac signal is not compliant with a predetermined cardio-profile, an anomaly results. The resultant anomaly, and the perturbation causing the anomaly are then evaluated to determine whether an appropriate action is required.

Abstract: An integrated circuit chip and method for EEG monitoring. In one embodiment, the integrated circuit chip includes an Analog Front End cell in communication with an electrode and a Classification Processor wherein a signal received from the electrode is processed by the Classification Engine cell and designated as seizure or non-seizure. In another embodiment, the Analog Front End cell includes an amplifier cell in communication with an electrode; and an ASPU cell in communication with the amplifier cell. In yet another embodiment, the Classification Processor includes a DBE Channel Controller cell; a Feature Extraction Engine Processor cell, and a Classification Engine cell in communication with the Feature Extraction Engine Processor cells and the DBE Channel Controller cell.

Abstract: A method and system for determining a signal quality metric of a cardiovascular time series utilizing a wireless sensor device are disclosed. In a first aspect, the method comprises determining subsequent values of the cardiovascular time series and comparing the determined subsequent values to a threshold value. In a second aspect, a wireless sensor device comprises a processor and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to determine subsequent values of the cardiovascular time series and compare the determined subsequent values to a threshold value.

Abstract: A method and system for detecting the onset of seizures comprising a measuring unit (1) having one or more sensors for detecting the electromyographic signal of one or more muscles of the user. The sensors are connected to a pre-processing module (3) comprising a high-pass filter which filters out noise and motion artefacts related to normal muscle activities. The preprocessing module is connected to a feature extraction module (4) comprising a threshold detector which counts the number of crossings with a hysteresis within a predetermined time window. The feature extraction module is connected to a classification module (5) which compares the extracted features to a first and second threshold and generates an event signal if the extracted features are above the first and second threshold.

Abstract: The system and method provide for electrocardiogram analysis and optimization of patient-customized cardiopulmonary resuscitation and therapy delivery. An external medical device includes a housing and a processor within the housing. The processor can be configured to receive an input signal for a patient receiving chest compressions and to select at least one filter mechanism and to apply the filter mechanism to the signal to at least substantially remove chest compression artifacts from the signal. A real time dynamic analysis of a cardiac rhythm is applied to adjust and integrate CPR prompting of a medical device. Real-time cardiac rhythm quality is facilitated using a rhythm assessment meter.

Abstract: An implantable cardioverter defibrillator (ICD) performs a method that includes determining whether first criteria for detecting a ventricular tachyarrhythmia are met by a cardiac electrical signal. The ICD determines features from cardiac signal segment of a group of cardiac signal segments and determines whether a first portion of the features satisfy monomorphic waveform criteria and determines whether a second portion of the features satisfy supraventricular beat criteria. The ICD determines whether second criteria for detecting the ventricular tachyarrhythmia are met and withholds detecting of the ventricular tachyarrhythmia in response to the monomorphic waveform criteria and the supraventricular beat criteria being met.

Abstract: A cardiac monitoring and/or stimulation system includes a housing coupled to a plurality of electrodes configured for subcutaneous non-intrathoracic sensing. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal from the plurality of composite signals, and identifies the separated signal as a cardiac signal using information derived from a non-electrophysiologic sensor, such as an accelerometer or acoustic transducer. The signal processor may iteratively correlate separated signals from the plurality of composite signals with a non-electrophysiologic sensor signal until the cardiac signal is identified.

Abstract: Disclosed herein is quantitative evaluation of sensitivity including: extracting cerebral physiological information items respectively related to axes of a multi-axis sensitivity model from regions of interest relevant to pleasure/displeasure, activation/deactivation, and a sense of expectation, the axes including a pleasure/displeasure axis, an activation/deactivation axis, and a sense of expectation axis; and evaluating the sensitivity using the cerebral physiological information items of the axes of the multi-axis sensitivity model.

Abstract: Provided is a physiological information detection sensor capable of implementing miniaturization by substantially securing a creepage distance and an air distance (e.g., implementing defibrillation protection). The physiological information detection sensor includes: a plurality of first substrates arranged in multiple tiers; a second substrate; a first connecting portion that electrically connects adjacent first substrates to each other among the plurality of first substrates; and an insulating member. Each of the plurality of first substrates has a defibrillation protection resistor mounted thereon and electrically connected to a physiological information detection unit. The second substrate has a circuit mounted thereon to process physiological information input from the physiological information detection unit via the defibrillation protection resistor. The insulating member is disposed between adjacent first substrates among the plurality of first substrates.