Abstract: Systems, methods and related devices used to produce and collect polarized noble gas to inhibit, suppress, detect or filter alkali metal nanoclusters to preserve or increase a polarization level thereof. The systems can include a pre-sat chamber that has an Area Ratio between 20 and 500.

Abstract: This disclosure relates to specific nanometer-sized nanoparticles made from unmodified dextran (DNPs), DNP conjugates, and related compositions and methods of use.

Abstract: A portable baby bottle sterilization device includes a housing having disposed therein an inner lining defining a bottle sterilization cavity, wherein the bottle sterilization cavity includes an opening, and wherein the inner lining is configured to receive one or more baby bottles therein through the opening, a power source, a plurality of UV LEDs coupled to the power source and to the inner lining, wherein the plurality of UV LED configured to provide UV-C light within the bottle sterilization cavity, and a processor coupled to the power source and to the plurality of UV LEDs, wherein the processor is configured to control intensity and duration of the UV-C light within the bottle sterilization cavity, and a cover coupled to the housing, wherein the cover is repositionable relative to the housing, wherein the cover can be positioned to removably cover the opening of the bottle sterilization cavity.

Abstract: A sanitizing assembly for sanitizing passenger seats of an airplane includes a power module, a pump, a tank, and plurality of dispensers. The power module, the pump, the tank, and the plurality of dispensers are coupled to and positioned in an airplane. The pump is operationally coupled to the power module. The tank is fluidically coupled to the pump. The tank is configured to store a sanitizer solution. The plurality of dispensers is fluidically coupled to the pump. Each dispenser is positioned proximate to a respective seat of the airplane. The pump is positioned to compel the sanitizer solution from the tank to the plurality of dispensers. The sanitizer solution is sprayed onto the seats to sanitize the seats.

Abstract: A cleaning device for LADs, and other such threaded devices, comprising a cap and a cleaning agent. The cap comprises a casing having an opening to an interior cavity. A threaded coupling mechanism is located on the inner surface of the casing proximate the opening. The coupling mechanism has retention features that provide localized pressure points on the threads of the LAD to accommodate thread variance and reduce the chance of premature disengagement.

Abstract: The present invention relates to the field of malodor counteraction. More particularly, it concerns malodor masking ingredient having an indane moiety (as defined in formula (I)), as well as malodor masking compositions comprising such ingredients.

Abstract: An electronic scented candle is described that includes a flame piece, a shell including an installation chamber, a fragrance container that is removably positioned inside the installation chamber, a scent chamber, and a liquid suction channel positioned within the fragrance container. One end of the liquid suction channel protrudes from the fragrance container into the scent chamber and anther end of the liquid suction channel is positioned within the fragrance container to draw a fragrance material from the fragrance container to the scent chamber. A scent outlet in communication with the scent chamber allows scent from the chamber to reach an external environment of the electronic scented candle, and an air inlet in communication with the scent chamber directs air from the external environment to the scent chamber. A heating device heats the content of the scent chamber to allow rapid dissemination of the scent chamber into an external environment.

Abstract: An air freshener for vehicles including a main body for holding a container for volatile substances and a foldable clip which can be placed in a substantially perpendicular position with respect to the main body. The foldable clip is rotatable with respect to the main body. The clip is always connected with the main body, so that it is sold with it occupying a reduced space in the package. The clip can be rotated to be adapted to any kind of ventilation grids.

Abstract: An ultraviolet germicidal irradiation device relating to reducing air-borne contaminants within air passing through an air-distribution duct. The device uses ultraviolet light source configured to produce germicidal UV-C light, a switchless current-conducting circuit configured to continuously conduct electrical current between a battery source and the at least one electrically-operated ultraviolet light source, and a housing to house electrically-operated ultraviolet light source and the switchless current-conducting circuit. The housing includes a mount configured to mount the housing within the air-distribution duct, a battery compartment adapted to hold the battery source, and at least one ultraviolet-light passage adapted to pass the germicidal ultraviolet light from the electrically-operated ultraviolet light source through the housing.

Abstract: A disinfecting vanity mirror includes a mirror panel having a top end, a bottom end and lateral edges when mounted on a wall. The mirror is moveably mounted on a hinge along one lateral edge mounted to space the panel from the wall to create a plenum space behind the mirror panel to allow air to enter through the bottom end to rise and exit through the top end. A source of UV light is provided in proximity to the plenum space to sanitize the air moving upwardly through the plenum space. A controller is programmed to interrupt or discontinue the generation of UV light when a motion detector senses motion in proximity to the mirror and/or in accordance with a programmed sequence of on and off times for energizing and de-energizing the source of UV light.

Abstract: Provided is an indoor air cleaning device for a vehicle using a nonthermal plasma, and more particularly, to an indoor air cleaning device for a vehicle using a nonthermal plasma, in which ozone is generated by a nonthermal plasma through corona discharge and an air purifying filter is sterilized through strong oxidization action of ozone, achieving more hygienic and continuous management, static electricity of an electrostatic filter is recharged with the controlled magnitude of applied voltage to maintain the best purification performance of the filter, and negative ions beneficial for human body are generated, creating pleasant indoor air conditions.

Abstract: Provided herein are synthetic antibacterial peptides that have a sequence at least 80% identical to a sequence shown in SEQ ID NO: 2 or the diastereomer thereof with a sequence shown in SEQ ID NO: 3 or pharmaceutical compositions thereof. Also provided are methods for stimulating wound healing via the synthetic antibacterial peptides and for forming an antimicrobial coating on contact lenses. In addition a device is provided that has a surface with a coating of the synthetic antibacterial peptides.

Abstract: Provided is a chitosan based hemostatic formulation comprising carboxymethyl chitosan, and methyl cellulose. More particularly, provided is a chitosan based hemostatic formulation comprising carboxymethyl chitosan, methyl cellulose, hydroxy ethyl cellulose, and calcium alginate. Also provided is a chitosan based hemostatic sponge comprising carboxymethyl chitosan, and methyl cellulose. More particularly, provided is a chitosan based hemostatic sponge comprising carboxymethyl chitosan, methyl cellulose, hydroxy ethyl cellulose, and calcium alginate. Further provided is a method of making and using the chitosan based hemostatic sponges.

Abstract: A method of forming a hemostatic product. A solution is formed with a polymeric material. An electrospinning system is provided having a first nozzle and a second nozzle. The polymeric material solution is passed through the first nozzle and a hemostatic agent is passed through the second nozzle to form an electrospun fiber in which the polymeric material at least partially covers the hemostatic agent. The electrospun fiber is deposited on a support to form the hemostatic product.

Abstract: A releasably adhesive laminate (1) comprises a structural layer (2) carrying on at least part of one side thereof a hydrophobic gel (4) and on at least part of the other side thereof a pressure-sensitive adhesive (3). The structural layer (2) is preferably a film of synthetic plastics material, eg polyurethane. The pressure-sensitive adhesive (3) is preferably an acrylic adhesive, and the hydrophobic gel (4) is preferably a silicone gel. The laminate (1) may be used as a skin contact component of a wound dressing or in numerous other applications.

Abstract: The present invention relates to water soluble and completely absorbable and/or physiologically degradable hemostatic compositions having a wax or wax-like base effective for tamponade hemostasis of bone or cartilage.

Abstract: In some embodiments, the present invention provides compositions including silk fibroin, at least one hydrophilic agent, and at least one catechol donating agent, wherein the at least one hydrophilic agent and at least one catechol donating agent are conjugated to the silk fibroin. According to various embodiments, at least a portion of the silk fibroin may be crosslinked. In some embodiments, the silk fibroin is at least 50% (e.g., 60%, 70%, 80%, 90%, 95% or more) crosslinked. In some embodiments, the present invention also provides methods for making such compositions.

Abstract: This invention is in the field of synthesis and amplified photodegradation of hydrogel network and methods of producing and using the same.

Abstract: A metal device that is at least partially formed of a novel copper and tungsten alloy.

Abstract: A cell growth inhibiting polymer for use in an ophthalmic implant includes at least one cell growth inhibiting monomer; and at least one other monomer selected from an acrylic monomer, a hydrophobic acrylic monomer, a hydrophilic acrylic monomer, a silicone monomer, a vinyl monomer and/or a collagen monomer.

Abstract: A penis size enlargement and to hyaluronic acid compositions for use in penis injections. It also relates to penoplasty by injection of hyaluronic acid. It relates more particularly to a composition including at least one crosslinked hyaluronic acid, used in the treatment of locker room syndrome, characterized in that it is administered at a dose of at least 0.15 mL/cm2, and in that said composition is administered repeatedly, and a first administration is followed by n subsequent administration(s) spaced by a time interval from 6 and 20 months, where n?1.

Abstract: It is an object of the present invention to provide a cell construct for cell transplantation that does not contain a substance having cytotoxicity, such as glutaraldehyde, and suppresses the necrosis of the transplanted cells in the construct (namely, having a high cell survival rate). The present invention provides a cell construct for cell transplantation comprising biocompatible polymer blocks that do not contain glutaraldehyde and at least one type of cells, wherein a plurality of biocompatible polymer blocks are disposed in gaps among a plurality of cells, and wherein the biocompatible polymer blocks have a tap density of 10 mg/cm3 or more and 500 mg/cm3 or less, or the value of the square root of the cross-sectional area/boundary length in the two-dimensional sectional image of the polymer block is 0.01 or more and 0.13 or less.

Abstract: The present invention provides protein-polymer conjugates, and methods for generating biocompatible scaffolds formed of hydrogels comprising the conjugates and use of the scaffolds for tissue regeneration. The present invention provides improved processes for the preparation of the conjugates, wherein the conjugates of the invention are preferably produced in an environmentally friendly process avoiding polar organic solvents.

Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 90% or less is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film. If necessary, a metal oxide layer made of a metal oxide having an isoelectric point of less than 7 is formed on the bioimplant thereby suppressing adhesion of bacteria.

Abstract: A spherical particle comprising decellularized omentum being between 1 nM-300 ?M in diameter is disclosed. In some embodiments, the particle comprises biological cells. In other embodiments, the particle comprises a biomolecule. Uses of the particles are also disclosed.

Abstract: A method of making a bone matrix includes exposing a bone tissue to a solution including a surfactant and a protease; treating the bone tissue with an acid solution following exposing the bone tissue; and electrophoretically treating the acid treated bone tissue. A bone matrix has a DNA content of not greater than 0.1 micrograms per milligram sample and a modulus in a range of 180 kPa to 250 kPa.

Abstract: Engineered tissue compositions for supporting cell growth, maintenance, and/or differentiation featuring a scaffold, extracellular matrix (ECM) material, and optionally a population of ECM-generating cells such as fibroblasts. The tissue compositions may be used for supporting seeded cells of a particular cell type of interest such as cells related to skeletal muscle, smooth muscle, cardiac tissue, gastrointestinal tissue, etc. The tissue compositions with seeded cells may develop into functional tissues, which may have the potential to provide a tissue graft for therapeutic purposes or a valuable model for in vitro assays.

Abstract: A method of preparing a decellularized placental membrane is provided. The method comprises removing cells from a pre-decellularized placental membrane comprising an amnion layer and a chorion layer to produce a decellularized placental membrane without separating the amnion layer from the chorion layer. The pre-decellularized placental membrane is obtained from an amniotic sac, and the decellularized placental membrane comprises the amnion layer and the chorion layer. Also provided is a decellularized placental membrane and a placenta-derived graft comprising the decellularized placental membrane. Further provided are the uses of the decellularized placental membrane or the placenta-derived graft.

Abstract: Compositions and methods of transplanting cells by grafting strategies into solid organs (especially internal organs) are provided. These methods and compositions can be used to repair diseased organs or to establish models of disease states in experimental hosts. The method involves attachment onto the surface of a tissue or organ, a patch graft, a “bandaid-like” covering, containing epithelial cells with supporting early lineage stage mesenchymal cells. The cells are incorporated into soft gel-forming biomaterials prepared under serum-free, defined conditions comprised of nutrients, lipids, vitamins, and regulatory signals that collectively support stemness of the donor cells. The graft is covered with a biodegradable, biocompatible, bioresorbable backing used to affix the graft to the target site. The cells in the graft migrate into and throughout the tissue such that within a couple of weeks they are uniformly dispersed within the recipient (host) tissue.

Abstract: Compositions and methods of transplanting cells by grafting strategies into solid organs (especially internal organs) are provided. These methods and compositions can be used to repair diseased organs or to establish models of disease states in experimental hosts. The method involves attachment onto the surface of a tissue or organ, a patch graft, a “bandaid-like” covering, containing epithelial cells with supporting early lineage stage mesenchymal cells. The cells are incorporated into soft gel-forming biomaterials prepared under serum-free, defined conditions comprised of nutrients, lipids, vitamins, and regulatory signals that collectively support stemness of the donor cells. The graft is covered with a biodegradable, biocompatible, bioresorbable backing used to affix the graft to the target site. The cells in the graft migrate into and throughout the tissue such that within a couple of weeks they are uniformly dispersed within the recipient (host) tissue.

Abstract: A composition comprising polymer particles and a carrier, wherein the polymer particles are a mixture of at least a first polymer and a second polymer, wherein the first polymer is at least partially soluble or dispersible in the carrier, and wherein the polymer particles are arranged such that they can join together to form a scaffold of polymer particles, and wherein the composition is administrable to a human or non-human animal.

Abstract: In some embodiments, the present invention provides compositions that comprise: (1) a biodegradable polymer matrix; and (2) at least one biodegradable reinforcing particle that is dispersed in the matrix. In some embodiments, the biodegradable reinforcing particle is selected from the group consisting of porous oxide particles and porous semiconductor particles. In additional embodiments, the compositions of the present invention further comprise a (3) porogen particle that is also dispersed in the matrix. In further embodiments, the compositions of the present invention are also associated with one or more active agents. In various embodiments, the active agents are associated with the biodegradable polymer matrix, the biodegradable reinforcing particle, and/or the porogen particle. In various embodiments, the compositions of the present invention may be utilized as scaffolds, such as scaffolds for treating bone defects.

Abstract: The present disclosure relates to a method for bonding a polyurethane polymer to a substrate using a multi-layered adhesion approach. Steps of the method include A) selecting a polyurethane polymer to be bonded to the substrate (100); B) depositing an SiO2 layer (200) onto the substrate (100); C) contacting the SiO2 layer (200) with a hydroxysilane compound, thereby forming a first adhesive layer (300) bonded to the SiO2 layer (200); D) contacting the first adhesive layer (300) with a urethane (meth)acrylate compound, thereby forming a second adhesive layer (400) bonded to the first adhesive layer (300); E) contacting the second adhesive layer (400) with a polyurethane (meth)acrylate compound, thereby forming a third adhesive layer (500) bonded to the second adhesive layer (400); F) contacting the third adhesive layer (500) with the polyurethane polymer selected in step A); G) solidifying the polyurethane polymer of step F).

Abstract: Disclosed are biocompatible, biodegradable, implantable devices for the controlled release of bioactive molecules. In particular embodiments, nanotechnology-based tunable implants are disclosed for 1) localized delivery of analgesics to treat postoperative pain; 2) sustained delivery of growth factors to promote vascularization; and 3) directing tissue regeneration, including the self-direction of autologous stem cells for organ remodeling.

Abstract: A waste collection system for collecting medical/surgical waste. A mobile rover includes at least one waste container supported on the mobile rover for storing the medical/surgical waste. A chassis is separate from and configured be removably coupled with the mobile rover. The chassis supports a chassis controller and a vacuum pump configured to draw a vacuum on the waste container. A rover controller is supported on the mobile rover and configured to receive a pressure signal representative of a level of the vacuum. The chassis controller is configured to be in communication with the rover controller and to regulate the level of the vacuum drawn based on the pressure signal. A transmitter may be supported on the mobile rover and in communication with the rover controller, and a receiver may be supported on the chassis to be in communication with the transmitter to establish a communication circuit for data transfer.

Abstract: A medical push button valve having a valve housing, a flow channel formed in the valve housing as well as a valve piston which is arranged displaceably in the valve housing between a position releasing the flow channel and a position closing the flow channel. The valve piston is operatively connected with a pressure element mounted on the valve housing and is spring-loaded via at least one spring element. The valve piston is biased into the position closing the flow channel with the spring-loaded pressure element. In order to provide a medical push button valve which allows for a simple and fatigue-free one-handed operation, the spring-loaded pressure element can be locked in at least one position in which the valve piston operatively connected with the pressure element at least partially releases the flow channel.

Abstract: Devices with a motor that, when connected to a cannula, rotates the cannula while removing adipose tissue from a surgical site. The device provides a direct pathway, for aspirated adipose tissue, from a tip of the cannula to a location where tubing is attached to the device. The pathway does not pass through the motor that provides the angular rotation of the cannula. Instead, the path for the adipose tissue passes through a removable coupler that is connected to the cannula. The cannula may also have a direct flow path for adipose tissue that does not pass through the motor.

Abstract: Contemplated within the scope of the invention are Yankauer suction systems having clog removal functionality and related methods. Specifically, the system, for use with a Yankauer suction tip, includes a medial tube that is hollow and has a coupling end and a distal outlet. The coupling end is connectable to a Yankauer suction tip and the distal outlet is in fluid communication with each of a flow pump and a suction source. Also included are systems having a medial tube that is hollow and comprises a coupling end, wherein the coupling end is connectable to a Yankauer suction tip; a suction conduit that extends distally from the medial tube to a suction source, wherein the suction conduit is in fluid communication with the suction source and the coupling end; and a flow conduit that extends distally from the medial tube and is in fluid communication with a flow pump and the coupling end.

Abstract: Fluid supply systems and methods for therapeutic fluid delivery systems, including those used for negative pressure wound therapy (NPWT) systems and methods.

Abstract: The invention relates to a connection device (2) for use in the negative pressure therapy of wounds, comprising a flexible conducting means (6) and a connecting body (4) made of an elastomeric flexible material which can be applied to a negative pressure dressing which covers the wound and seals the wound off from the atmosphere, wherein the connecting body (4) has a centrally arranged raised first area (8) which receives the conducting means (6), and a flatter flange-shaped second area (10) opposite the first area, which second area forms a contact plane (12) on the negative pressure dressing, wherein a conducting portion (46) which is closed on all sides and is formed by the central first area adjoins a free end of the delivery lumen (42) of the conducting means (6) which opens in the central first area, wherein said conducting portion first opens at a distal end into an interior (16) of the central first area (8) and from there is in fluid communication with the suction lumen (40) of the conducting means (

Abstract: Apparatus for the application of topical negative pressure therapy to a wound site is described, the apparatus comprising: a wound contacting element for retaining wound exudate fluid therein; a wound covering element that provides a substantially airtight seal over the wound contacting element and wound site; a vacuum connection tube connecting a wound cavity to a vacuum source; and a vacuum source connected to a distal end of the vacuum connection tube.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: A system for facilitating fluid connection between cannulae and a blood pump. The system includes a cannula having a distal end adapted to be in fluid communication with the circulatory system and a proximal end configured to couple to an inlet of the blood pump. Further included is a tunneling device configured to be inserted into a body of a patient to direct the proximal end of the cannula adjacent to the inlet and including a second connecting structure. Further included is a plug which has a first plug part and a second plug part. The first plug part includes a second connecting structure, the first and second connecting structures being selectively engageable. The second plug part is configured to be inserted in the proximal end of the cannula. The first and second plug parts are selectively disengageable to allow in situ disconnection between the cannula and tunneling device.

Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.

Abstract: A blood pump for supporting the heart may be provided that includes: a rotor with delivery elements; a rotor drive; a pressure sensor; and a regulating device that regulates a pressure or a hemodynamic parameter by means of control of the rotor drive. The pressure and/or the hemodynamic parameter may be determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the pump. The regulating device may be suitable for regulating a hemodynamic parameter successively, such as periodically, to different target values. Using such regulation, the blood pump may be operated in an optimized manner, and operation of the blood pump may be varied in a targeted and patient-protective manner in order to attain certain goals.

Abstract: A heart pump is provided with a delivery channel and with a delivery device for blood, which is arranged in this delivery channel, wherein the delivery channel at least partly runs in a pump tube. A first sensor device for measuring the oxygen saturation of the blood, is provided on the heart pump, in particular on a wall of the delivery channel, in particular on the pump tube. A control device can also be integrated into the pump. Thereby, additional monitoring and control possibilities result.

Abstract: A system and method for monitoring and/or remote control of a dialysis machine includes: providing a display device, wherein the display device comprises a display and a processor, providing graphical user interface (GUI) layout resources and/or dynamic data, interpreting the GUI layout resources and/or the dynamic data by the processor, and outputting of a screen layout by the processor. The system and method provide for monitoring and/or remote control of a dialysis machine through the use of one or more cloned or reconstructed interfaces.

Abstract: A wall-mounted hemodialysis supply box and drain cabinet for use in continuous renal replacement therapy is provided that comprises a corrosion-resistant enclosure defining an interior space having a forwardly facing opening with a hinged door, at least one water-supply valve, at least one variable height bag holder, a bottom wall with a drain, and a plurality of inclined inside walls configured to channel waste water and treatment fluids into the drain. A sprayer hose attachment for use in washing down and cleaning the interior space is also disclosed.

Abstract: A system and apparatus for opening and emptying a bag of material includes a base having a pair of opposed sides and a central aperture through which material may flow. The system includes a pair of opposed doors rotatably mounted on a pair of door shafts, the edges of the pair of opposed doors forming an opening and a plurality of piercing blades pivotally mounted to the base on a pivot rod, the blades capable of pivoting to pierce said bag. The system further includes a cutting blade mounted transversely below the opening of the opposed doors, the cutting blade capable of linear motion across the opening.

Abstract: A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include a control system that can adjust the volume of fluid infused into the peritoneal cavity to prevent the intraperitoneal fluid volume from exceeding a pre-determined amount. The control system can adjust by adding one or more therapy cycles, allowing for fill volumes during each cycle to be reduced. The control system may continue to allow the fluid to drain from the peritoneal cavity as completely as possible before starting the next therapy cycle. The control system may also adjust the dwell time of fluid within the peritoneal cavity during therapy cycles in order to complete a therapy within a scheduled time period.