Abstract: Methods for diagnosing pathology of the liver in subject suspected of having such pathology by measuring the glycosylation of anti-gal IgG in various biological fluids of the subject.

Abstract: A method for predicting cellular, tissue and clinical radiosensitivity, which is based on the determination and correlation of multiple parameters and cellular and enzymatic criteria.

Abstract: A method is described to obtain a class of embryos having a higher implantation potential than from morphology selection alone by selecting from a plurality of embryos, obtained by fertilizing the plurality of oocytes, a class of embryos having a high implantation potential. The selection is determined from a level of granulocyte-colony stimulating factor (G-CSF) present in the follicular fluid (FF) of each oocyte in the plurality of oocytes.

Abstract: The present invention provides a cocaine aptamer represented by the following chemical formula (Cl), R-DNA-L-Fc??(Cl) where R is selected from the group consisting of a hydrocarbon group and the derivative thereof; DNA consists of a gene sequence capable of binding to cocaine; L is a linker represented by ((CH2)2—O)n1—PO4—(CH2)n2-L1; L1 is absent or an optional linker; n1 represents a natural number; n2 represents a natural number; and Fc represents a ferrocene group. The cocaine aptamer is capable of detecting cocaine with high sensitivity.

Abstract: A method of operating a data processing system to operate a first instrument and a second instrument connected to the data processing system is disclosed. The method includes displaying a measurement table. The data processing system receives user input defining a first parameter that is to be varied during a testing procedure by the first instrument and a first measurement to be made by the second instrument during the test procedure, a plurality of first parameter values to be used in the testing procedure. The data processing system causes the first instrument to provide each of the first parameter values and the second instrument to make the measurement and enter the measurement in a corresponding cell of a second row in the measurement table when the first instrument provides each of the first parameter values.

Abstract: The invention relates to a microplate reader and a respective method, wherein the microplate reader comprises at least one measuring device and a holding device for accommodating at least one microplate and for positioning the samples-containing wells of this(these) microplate(s) in relation to the at least one measuring device. The at least one measuring device is used for detecting light which is emitted by samples in wells of a microplate inserted in this microplate reader and/or which is influenced by samples transilluminated by light in wells of a microplate inserted in this microplate reader. The microplate reader comprises a control unit for controlling the temperature of a gas atmosphere surrounding the wells containing the samples of microplates used in this microplate reader.

Abstract: A sample consumable that carries a microvolume of sample to a sample loader. The consumable is precisely aligned utilizing a double-alignment feature to the loader. The loader is based on a crank-slider geometry and allows for simple, one-handed operation for the user. Overall, the consumable and sample loader increase reproducibility of in-line sample loading and offers ease-of-use.

Abstract: The invention relates to a signal inducing device (1, 9, 11, 12, 18, 19, 20), comprising a first material (2, 3, 13, 14) and a second material (4, 16). The first material (2, 3, 13, 14) and the second material (4, 16) show a different magnetic behaviour. The first material (2, 3, 13, 14) and the second material (4, 16) are arranged in a way that the resulting magnetic behaviour of the signal inducing device (1, 9, 11, 12, 18, 19, 20) varies over a magnetic interaction surface (5, 10) of the signal inducing device (1, 9, 11, 12, 18, 19, 20). The signal inducing device (1, 9, 11, 12, 18, 19, 20) is designed in a way that the magnetic interaction surface (5, 10) shows an essentially smooth surface, in particular with respect to the standard moving direction of the magnetic interaction surface (5, 10).

Abstract: The present disclosure relates to a rotation speed sensor, including at least one sensor element to detect a magnetic input signal of the rotation speed sensor, a time watchdog with a programmable time constant and an output control circuit. The time watchdog generates a time-out event when no minimum or maximum or no output switching event of a magnetic input signal of the rotation speed sensor is detected within a time-interval equal to a programmed time constant of the time watchdog. Further, the output control circuit changes the output signal of the rotation speed sensor from a first value to a second value, when a minimum or a maximum or output switching event of the magnetic input signal is detected within the time interval and a change of the magnetic input signal is greater than a predetermined value.

Abstract: An accelerometer includes a first stator, a second stator, a proof mass assembly disposed between the first stator and second stator, and a controller. The first stator includes a first magnet and the second stator includes a second magnet. The proof mass assembly includes a first coil configured to receive a first amount of current and a second coil configured to receive a second amount of current. The controller is configured to distribute the first amount of current to the first coil and the second amount of current to the second coil. The first amount of current is different than the second amount of current.

Abstract: The invention relates to a device and to a method for determining a voltage. The voltage to be determined is a direct voltage at the input of a flyback converter. The flyback converter comprises at least a flyback-converter transformer and a switching element on the primary side of the flyback-converter transformer. In order to determine the voltage at the input of the flyback converter, a voltage on the secondary side of the flyback-converter transformer is sensed and evaluated in correlation with the switching state of the switching element on the primary side.

Abstract: Electrical current sensing and monitoring methods include connecting sensing a voltage across a conductor having a non-linear resistance such as a fuse element. The current flowing in the conductor is calculated based on at least a first detected state of the sensed voltage and a thermal equilibrium characterization of the conductor.

Abstract: A delta-sigma modulator circuit comprising: an integrator circuit configured to produce an integrator output signal that represents an integration of an analog input signal, a comparator output signal and a periodic signal; a comparator circuit configured to produce the comparator output signal in response to a comparison of the integrator output signal with a first reference signal; and a periodic signal generation circuit configured to produce the periodic signal.

Abstract: A probe system includes a heater and a control circuit. The heater includes a resistive heating element routed through the probe. An operational current is provided to the resistive heating element to provide heating for the probe. The control circuit is configured to monitor the operational current over time and determine a half-life estimate of the resistive heating element based upon an exponential function of the operational current over time.

Abstract: A transmitter with universal terminals supports flexible connection of an RTD sensor. The transmitter includes a plurality of terminals, a first switch, a second switch, and a microcontroller. The first switch is coupled to the plurality of terminals and a current source. The second switch is coupled to the plurality of terminals and a sink resistor. The microcontroller receives an indication that a sensor is connected to an undetermined number of the terminals. The microcontroller transmits control signals to the first switch and the second switch to test a voltage differential between each of a plurality of combinations of the terminals. The microcontroller determines which of the terminals are coupled to the sensor. The microcontroller sets the determined terminals as inputs received from the sensor.

Abstract: A system for monitoring an electric power delivery system by obtaining high-frequency electric power system measurements and displaying event information is disclosed herein. The system may use the high-frequency electric power system information to detect traveling waves. The system may generate a display showing fault location on the electric power system, and timing of traveling waves received at locations on the electric power system. The display may include time on one axis and location on another axis. The display may include a waterfall display.

Abstract: A test tool for a low voltage devices is described. The test tool comprises a voltage sensor, a current sensor, a diode sensor, a testing module, and an indicator. The voltage sensor determines a voltage between a first and second electrical wire from an alternating current (AC) transformer. The current sensor determines a current between the first and second electrical wires. The diode sensor determines a presence of a diode connected to the first and second electrical wires based on the current and the voltage. The testing module identifies one or more installation diagnostics related to a device to be coupled with the AC transformer. The indicator generates a visual or audible indicator corresponding to the one or more installation diagnostics.

Abstract: Methods and systems for sourcing and/or sinking current from power supplies of differing voltage levels. A driving circuit may, for example, receive power from first and second power supplies, where the first power supply provides current to the driving circuit at a first voltage level and the second power supply provides current to the driving circuit at a second voltage level, and where the first voltage is greater than the second voltage. As a result, the first power supply allows the driving circuit to provide current over a wide voltage range, and the second power supply allows the driving circuit to provide current at lower voltages with less power consumption.

Abstract: A method of testing a semiconductor wafer comprising a scribe line and a plurality of dies. The method includes implementing a first landing pad on the scribe line and implementing a first interconnect on the scribe line and between the first landing pad and a first cluster of the plurality of dies, thereby coupling the first landing pad to the first cluster of dies. The method also includes performing the testing of the first cluster of dies using automated test equipment (ATE) coupled to a probe tip by contacting the first landing pad with the probe tip and applying an ATE resource to the first cluster of dies.

Abstract: Circuits and methods are provided for a signal path between circuit parts. During normal operation, a delay is deactivated. During a burn-in test, the delay is activated. In the deactivated state, a delay component may be disconnected from a supply voltage.

Abstract: A testing architecture for integrated circuits on a wafer includes at least one first circuit of a structure TEG realized in a scribe line providing separation between first and second integrated circuits. At least one pad is shared by a second circuit inside at least one of the first and second integrated circuits and the first circuit. Switching circuitry is coupled to the at least one pad and to the first and second circuits.

Abstract: The present disclosure relates to a system and method for performing scan chain diagnosis of an electronic design. The method may include identifying, at a computing device, at least one failing scan chain associated with the electronic design. The method may also include selecting a plurality of defect locations associated with the at least one failing scan chain, wherein the plurality of defect locations corresponds to a number of parallel patterns that a simulator is configured to process. The method may further include selecting a sliced failing pattern set and generating a plurality of copies of a pattern associated with the sliced failing pattern set, wherein each of the plurality of copies corresponds to one of the plurality of defect locations. The method may also include simulating the plurality of copies of the pattern in parallel.

Abstract: A measuring system for performing measurements on a device under test is provided. The measuring system comprises a measuring device, a probe connected to the measuring device, a power sensor and a positioning unit. The positioning unit is adapted to connect the probe to the power sensor in a first configuration and to the device under test in a second configuration. The measuring device is adapted to generate a first signal. The probe is adapted to supply the first signal to the power sensor and the first configuration and to supply the first signal to the device under test and the second configuration. The power sensor is adapted to determine the power of the first signal and the first configuration. The measuring device is adapted to regulate the power of the first signal in the second configuration based upon the power determined by the power sensor.

Abstract: A monitoring system is applied to an electrical system, which includes a DC power source and an electrical apparatus that is connected to the DC power source by a pair of electric power leads incorporating respective switches. To detect leakage current from the DC power source, a low-frequency AC signal is applied via a large-capacitance capacitor to a specific connection position, between a first terminal of the DC power source and the corresponding switch, and the resultant voltage of that signal is measured. To detect a short-circuit failure of one or both of the switches, a high-frequency AC signal is applied via a low-capacitance capacitor to the specific connection position, and the resultant signal voltage is measured. Judgement as to occurrence of leakage current and/or short-circuit failure is based on the measured signal voltage values.

Abstract: A characteristic, such as State Of Health (SOH) or State Of Charge (SOC), is estimated for an Energy Storage System (ESS) by supplying a pre-determined signal to the ESS, measuring a response signal output by the ESS, and obtaining an impedance spectrum of the ESS. In one example, the ESS is one of several electrochemical battery packs of an electric vehicle. The pre-determined signal is a current signal generated by a switching power converter that transfers charge from the battery pack to other battery packs or transfers charge from the other battery packs onto the battery pack. The pre-determined signal is generated without disrupting any load supplied by the battery packs. The battery pack outputs a voltage signal in response to receiving the pre-determined current signal. A processor obtains an impedance spectrum using the current and voltage signals, and thereby obtains an SOH and SOC estimate of the battery.

Abstract: A battery internal state estimation apparatus including: an internal state estimation unit, which inputs at least one of measured values obtained by a battery measurement unit at preset sampling intervals including a current flowing through a battery, an inter-terminal voltage, a temperature of the battery, and an ambient air temperature, for estimating, based on the measured values, at least one of a state of charge, internal temperature, capacity, and internal resistance of the battery as an internal state of the battery; and an internal state correction unit for correcting estimated values of the internal state obtained by the internal state estimation unit so that the estimated values are not contradictory at least to qualitative properties of the battery, and outputting the corrected values to an output unit.

Abstract: An AC component ?I addition unit of a diagnostic device superimposes an alternating current on an output current of a fuel cell. A Zn calculation unit calculates a cell impedance with respect to the alternating current with regard to any of a plurality of cells. A diagnosis unit diagnoses that any cell is subjected to hydrogen deficiency when an absolute value of the cell impedance exceeds (absolute value of a reference impedance+a predetermined value ?). It is diagnosed that any cell is subjected to oxygen deficiency when the absolute value of the cell impedance is smaller than (absolute value of the reference impedance?a predetermined value ?).

Abstract: A surgical apparatus is disclosed which comprises a handle module that is attachable to a detachable shaft module for collectively performing a surgical procedure. The handle module comprises a rotary drive system for driving the detachable shaft module, an electric motor coupled to the rotary drive system for powering the rotary drive system, one or more sensors for sensing the performance of the electric motor, and a handle module processor circuit in communication with the one or more sensors. The handle module processor circuit is programmed to monitor a performance parameter of the handle module based on input from the one or more sensors by monitoring whether the performance parameter is outside an acceptable performance band.

Abstract: A method for managing an electrochemical accumulator or a storage battery includes determining an estimated value of a state of deterioration of the accumulator from the accumulator's history of voltage values, intensity of current flow, and temperature. The estimated value is a barycentric value of the state of deterioration calculated as a barycenter of at least two values. The at least two values include a first value indicative of the state of deterioration of the accumulator calculated by a first method and a second value indicative of the state of deterioration of the accumulator calculated by a second method different from the first method. From an initial commissioning state of the accumulator, barycentric coefficients are varied at least once to calculate the next barycentric value when a previous value of the state of deterioration of the accumulator, calculated according to the first method, has passed a first threshold.

Abstract: Disclosed is an inspection apparatus for inspecting a chip for noise, including an inspection circuit that is connected to a first power line of the chip and that receives a signal to be inspected, wherein the first voltage is applied to the first power line and the signal to be inspected includes noise having a second voltage, and a voltage doubler that is connected to the first power line and boosts a voltage of driving power having the first voltage, wherein the inspection circuit may be driven by the driving power, the voltage of the driving power is boosted by the voltage doubler, and the inspection circuit inspects the chip for the noise of the signal to be inspected.

Abstract: An exemplary embodiment of the present invention provides a method for determining root causes of issues in an electrical grid. The method includes receiving local data from each of a plurality of meters. The local data may be indicative of voltage levels measured by the plurality of meters. The method also includes identifying abnormalities in the received local data. An abnormality is indicated by local data indicative of a voltage level that is outside of a predetermined range of acceptable levels. The method further includes associating each of the identified abnormalities with a respective meter and a geographic location of the respective meter and analyzing each of the identified abnormalities according to a predetermined set of evaluation factors to determine a root cause.

Abstract: An apparatus and a method for testing a magnetic field sensor are provided, in which the method includes arranging a coil for generating a magnetic field, applying the magnetic field to the magnetic field sensor using the coil, and detecting the magnetic field applied to the magnetic field sensor.

Abstract: A chip package, a chip package system, a method of manufacturing a chip package, and a method of operating a chip package including: a first sensor configured to measure a magnetic field component up to a maximum magnetic field value; a second sensor configured to measure the magnetic field component beyond the maximum magnetic field value; and a circuit coupled to the first sensor and the second sensor and configured to receive at least one sensor signal from at least one of the first sensor and the second sensor, wherein the circuit is further configured to select the first sensor or the second sensor to measure the magnetic field component based on the received sensor signal.

Abstract: A magnetic resonance imaging system and method are provided that include user control of certain functions using physical gestures, such as hand motions or the like. The gesture control aspects can include one or more cameras, and a processor configured to detect and recognize gestures corresponding to predetermined commands and to provide signals to execute the commands. A verification switch, such as a foot switch, can be included to improve safety and reliability of the gesture control aspects. This switch can be used to activate the gesture detection aspects and/or to confirm a recognized gesture command prior to its execution.

Abstract: Magnetic resonance imaging (MRI) systems and methods to effect improved and more efficient determination of the specific absorption rate (SAR) are described. The SAR is calculated based upon a derived relationship between a body surface area (BSA) and a portion of the total radio frequency (RF) energy delivered to RF transmit coil that is deposited in the imaging subject, and the scanning is controlled in accordance with the calculated SAR.

Abstract: There are provided a magnetic resonance imaging device and a method of controlling a MRI device. The MRI device includes an RF transmitting coil configured to transmit an RF to an object on a table; an object scanning unit including a position detecting unit configured to detect a position of the object and a thickness detecting unit configured to detect a thickness of the object, and configured to recognize a body shape of the object; and a control unit configured to regulate the RF to be transmitted, thereby compensating an RF field based on the recognized body shape of the object.

Abstract: A method of configuring a conducting grid of elements interconnected at intersecting nodes by switches is described.

Abstract: A magnetic resonance arrangement with a permanent magnet system and having magnet elements, pole piece elements and yoke elements of magnetic material arranged cylinder-symmetrically with respect to the z axis. The yoke elements have a first lid (11?) and a second lid (11?) and also a hollow cylindrical drum (12) arranged axially between the lids. The yoke elements enclose the measuring volume in the axial and radial direction. The magnet elements each include a pair of cylinder-symmetrical axial magnets (13?, 13?) and also radial magnet rings (14?, 14?). The axial magnets are each arranged axially adjoining the lids and are arranged radially within the radial magnet rings and respectively axially further away from the measuring volume than the radial magnet rings. The outer diameter of the axial magnets is less than or equal to the inner diameter of the radial magnet rings.

Abstract: Provided is a technique in calculating a magnetic susceptibility distribution by using an MRI, for reducing artifacts and noise and improving precision in the magnetic susceptibility distribution being calculated. According to this technique, a magnetic field distribution is obtained via a phase image from a complex image acquired through MRI. Under the constraint based on a relational expression between the magnetic field and the magnetic susceptibility, smoothing process is performed iteratively on the magnetic susceptibility distribution calculated from the magnetic field distribution. Specifically, a minimization process for minimizing through the iterative operation, an error function defined by a predetermined initial magnetic susceptibility distribution and the magnetic field distribution is performed, thereby calculating the magnetic susceptibility distribution.

Abstract: Systems and methods for magnetic resonance imaging (“MRI”) using a frequency swept excitation that utilizes multiple sidebands to achieve significant increases in excitation and acquisition bandwidth are provided. The imaging sequence efficiently uses transmitter power and has increased sensitivity as compared to other techniques used for imaging of fast relaxing spins. Additionally, the imaging sequence can provide information about both fast and slow relaxing spins in a single scan. These features are advantageous for numerous MRI applications, including musculoskeletal imaging, other medical imaging applications, and imaging materials.

Abstract: Systems and methods for producing a quantitative parameter map using a magnetic resonance imaging (MRI) system includes providing magnetic resonance fingerprinting (MRF) data acquired with an MRI system from a subject. The MRF data represents a plurality of different signal evolutions acquired using different acquisition parameter settings. The method also includes providing a database comprising a plurality of sub-dictionaries, each sub-dictionary including a plurality of signal templates, sequentially comparing the MRF data to each of the sub-dictionaries to estimate quantitative parameters, and generating a quantitative parameter map of the subject using the estimate quantitative parameters.

Abstract: J-resolved LASER and semi-LASER sequences for localized two-dimensional magnetic resonance spectroscopy are disclosed. After a delay time ?1 from application of an excitation RF pulse, a first pair of slice-selective adiabatic full-passage (AFP) pulses, separated by an inter-pulse interval ?2, is applied. At the end of the sequence a final pair of slice-selective AFP pulses, separated by a time of ?2/2+?1+t1/2 is applied, where t1 is the duration of an incremental evolution period corresponding to the indirect dimension of a 2D J-resolved spectrum. In the case of J-resolved LASER, an additional intermediate pair of slice-selective AFP pulses, separated by an inter-pulse interval ?2, is applied prior to the final pair of AFP pulses. An echo signal is acquired at time t1/2 from the application of the last AFP pulse.

Abstract: An embodiment in accordance with the present invention provides a new MRI method to image the buildup of exchange transfer processes from nuclei in mobile solute molecules in tissue via another molecule (e.g. solvent such as water). The pulse sequence can detect Chemical Exchange Saturation Transfer (CEST), relayed Nuclear Overhauser Enhancement (rNOE) CEST, and selective induced exchange transfer processes. Further, the proposed MRI pulse sequence involves acquiring two or more images with a difference in waiting period (delay) after a radiofrequency excitation, saturation pulse, or series of such pulses. This produces a series of exchange transfer images sensitive to the speed of transfer of changes in magnetization. Subtracting two images or fitting a time series produces maps with minimum interference from direct water saturation and from semi-solid magnetization transfer and other fast exchanging protons.

Abstract: A method of inducing spin polarization in an analyte is provided. The method exposes 14N spin defect centers embedded within 25 nm of a diamond surface to a magnetic field while an analyte is near the surface. The 14N spin defect centers are polarized by treatment with an electromagnetic wave protocol having a visible light pulse (p0); a microwave pulse (mw1), a radio frequency pulse (rf1), a microwave pulse (mw2) and a radio frequency pulse (rf2) resulting in polarization of the nuclear spins of the 14N spin defect centers. Polarized spins in the 14N spin defect centers induce spin polarization in the analyte.

Abstract: A magnetic resonance imaging apparatus according to an embodiment includes a sequence controller and a storage unit. The sequence controller acquires magnetic resonance signals of a target imaging part including cerebrospinal fluid flowing therein of a subject in a condition where a supply of oxygen is receivable, at a plurality of time phases in an oxygen inhalation process of the subject. The storage unit stores therein the magnetic resonance signals acquired at the time phases.

Abstract: The present invention provides methods for reducing SAR during real-time MR imaging. The method improves the safety of cine imaging, while, in certain embodiments, do not decrease image quality. The method of the invention thereby allows for the use of higher field strengths that are sometimes necessary to provide the most diagnostic information. The present invention also provides methods for improving contrast-to-noise ratio, while not increasing SAR.

Abstract: An imaging system (5) includes a plurality of coil channel receivers (26) and one or more processors or modules (38). The plurality of coil channel receivers (26) demodulate magnetic resonance data from a multi-channel coil (10) which includes a plurality of coil elements (16) spatially separated, each element transmitting magnetic resonance data on a corresponding channel (25). The one or more processors or modules (38) are configured to detect (26) artifacts in the magnetic resonance data on each channel individually. The one or more processors or modules (38) are further configured to select (27) the magnetic resonance data from the channels which include detected artifacts at or below a threshold artifact level and reconstruct (32) one or more images using the selected magnetic resonance data.

Abstract: 3D printing in MRI-compatible plastic resin has been used to fabricate and implement a geometric distortion phantom for MRI and CT imaging. The sparse grid structure provides a rigid and accurate phantom with identifiable intersections that are larger than the supporting members, which produces images that are amenable to fully automated quantitative analysis using morphometric erosion, greyscale segmentation and centroiding. This approach produces a 3D vector map of geometric distortion that is useful in clinical applications where geometric accuracy is important, either in routine quality assurance or as a component of distortion correction utilities.

Abstract: A MRI quality assurance device, according to the present invention, has a housing made of a rigid MRI invisible material containing one or more sealed reservoirs containing a fluid MRI signal producing material. Each sealed reservoir has a first volume portion and a second variable volume portion in fluid communication therewith.

Abstract: Described herein are systems and methods for improving performance of single-frequency (single-point, single-bin) discrete Fourier transform (DFT) detectors by elimination of systematic errors from the detector output. Calibration procedures known in the art for practical implementations of such detectors do not provide adequate reduction of these systematic errors thus reducing utilization of these detectors in useful applications and products. The described methods, systems and devices allow such detectors to measure both DC and AC signals and, in latter case, considerably expand the operation frequency range without any additional hardware. These methods enable wide practical applications of DFT detectors across diverse variety of fields: from monitoring health of mechanical structures and fluid properties to impedimetric measurements in electrochemistry, monitoring of corrosion and bioimpedance.