Patents Issued in January 22, 2019
  • Patent number: 10183100
    Abstract: A flow control system may include an inner nosecone having an inner nosecone distal end and an inner nosecone proximal end, an outer nosecone having an outer nosecone distal end and an outer nosecone proximal end, an aperture of the outer nosecone, a gasket having a gasket distal end and a gasket proximal end, a gasket aperture of the gasket, a gasket seal of the gasket, a flow control mechanism having a flow control mechanism distal end and a flow control mechanism proximal end, and a control aperture of the flow control mechanism. A rotation of the flow control mechanism about the gasket may be configured to decrease an aspiration flow rate. A rotation of the flow control mechanism about the gasket may be configured to increase an aspiration flow rate.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 22, 2019
    Inventors: Joshua C Arnone, Steven J Apperson, Gregg D Scheller
  • Patent number: 10183101
    Abstract: Embodiments of the present invention disclose a device for removing adipose tissue, comprising a self-contained syringe device comprising an inner syringe included within an outer syringe and wherein a filter is attached inside the outer syringe barrel; wherein the filter comprises a filter material that prevents premature filter collapse where the filter material is optionally coated to increase stiffness, and wherein liposuctioned adipose tissue is collected and purified inside the syringes. Methods of using the devices or system are also disclosed.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: January 22, 2019
    Assignee: Aurastem LLC
    Inventors: Bradford A. Conlan, Lucas Fornace
  • Patent number: 10183102
    Abstract: A hands-free breast pump comprises a funnel-shaped adsorption unit having an adsorption surface and a suction tank; a suction chamber having an extension part, the extension part having a connection pipe and a second suction hole formed on the lower portion of the inner peripheral surface, and a first coupling part extended downwardly from the extension part and having a third suction hole formed on the lower portion of the inner peripheral surface thereof; and a storage vessel coupled to the first coupling part in the horizontal direction with the adsorption surface to store the breast milk discharged from the backflow prevention unit therein.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: January 22, 2019
    Inventor: Sang Ha Kim
  • Patent number: 10183103
    Abstract: The invention relates to a cassette module for processing blood and therapeutic fluids in an extracorporeal blood treatment, dialysis or infusion technology, comprising a base body (302), with a first side and a second side, fluid channels integrated into the base body, a receiving unit (304) to receive a centrifugal pump means for delivering fluids, characterized in that at least some of the fluid channels are arranged on a first side of the base body, and the receiving unit for the centrifugal pump means is arranged on the second side, and the receiving unit for the centrifugal pump means is in fluid connection with the fluid channels on the first side during operation.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: January 22, 2019
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Christoph Wiktor, Alexander Heide, Manfred Weis, Goekhan Oerter, Marina Wenke, Udo Waeber
  • Patent number: 10183104
    Abstract: The invention features modular implantable ventricular assist devices configured to be, at least in part, assembled within a patient. The devices generally include a pump assembly and an expandable frame. The frame is configured to engage tissue of a patient when implanted. The pump assembly is configured to be operably coupled to the frame when the frame is implanted and in the expanded configuration.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: January 22, 2019
    Assignee: Medtronic Vascular Galway
    Inventors: Marc Anderson, Declan Costello, Marian Creaven, Paul Devereux, Niall Duffy, John Gallagher, John Milroy
  • Patent number: 10183105
    Abstract: An apparatus and method of determining the blood flow rate at which, in an extra-corporeal blood circuit of an extra-corporeal blood treatment apparatus, blood is pumped through the arterial blood line into the blood chamber of the dialyser and out of its blood chamber through the venous blood line is described. The method and apparatus provide for the determination of a plurality of parameters characteristic of the extra-corporeal blood treatment, with a given blood flow rate being determined in each case as a function of one of the characteristic parameters. A blood flow rate which is preset for the blood treatment is selected from the plurality of blood flow rates determined on the basis of the characteristic parameters. The blood flow rate to be preset is selected on the basis of a preset algorithm which may be implemented in software installed on a data processing unit or in hardware.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: January 22, 2019
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Pascal Kopperschmidt, Wolfgang Wehmeyer
  • Patent number: 10183106
    Abstract: A blood purification system includes a plurality of monitoring devices (1) each attached to a dialyzer (5) to perform a blood purification treatment on a patient. A dialysate supplying device (2) supplies a dialysate to each of the monitoring devices (1). The plurality of monitoring devices (1) and the dialysate supplying device (2) are connected to each other by a LAN cable ?. Thus, predetermined individual information relating to the plurality of monitoring devices (1) is transmitted from each of the monitoring devices (1) to the dialysate supplying device (2).
    Type: Grant
    Filed: November 30, 2013
    Date of Patent: January 22, 2019
    Assignee: Nikkiso Company Limited
    Inventors: Harutoshi Okabe, Hiroaki Suzuki, Masaru Kuchiki
  • Patent number: 10183107
    Abstract: A tube clamp for an extracorporeal circulator recognizes various abnormal situations of the tube clamp and notifies a user. The tube clamp has a lid sensor, a tube sensor, and a plunger sensor. In a case where any one of detection of the closure of a lid portion via the lid sensor, detection of the mounting of a tube via the tube sensor, and detection of the movement of a plunger via the plunger sensor is not obtained despite the fact that there is an instruction for blocking the tube, it is determined that the blocking is abnormal. In a case where the three states including the closed state, the mounting state, and the movement state are detected despite the fact that there is no instruction for blocking the tube, it is determined that the tube is erroneously blocked. Such abnormal situations are notified to a user via an alarm.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: January 22, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Tomoki Utsugida
  • Patent number: 10183108
    Abstract: A diafiltration system comprises a fluid treatment assembly comprising two or more fluid treatment modules, the fluid treatment assembly comprising a feed inlet, a permeate outlet, and a retentate outlet; each module comprising a cross flow treatment assembly including an ultrafiltration membrane and having a feed side and a permeate side, and a diafiltration fluid distribution plate comprising a diafiltration fluid feed inlet and a common feed permeate/diafiltration fluid permeate outlet port; two or more diafiltration fluid conduits, each conduit in fluid communication with a respective single diafiltration fluid feed inlet; and, a diafiltration fluid pump comprising at least a first multiple channel pump head having at least two channels including separate channels for separate conduits in fluid communication with respective single diafiltration fluid feed inlets, wherein the pump provides simultaneously controlled diafiltration fluid flow rates through each of the conduits to the respective diafiltration
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: January 22, 2019
    Assignee: Pall Corporation
    Inventors: Engin Ayturk, Catherine Casey
  • Patent number: 10183109
    Abstract: A dialysis system includes an on-line dialysate generator, a first dialysate pump in fluid communication with the on-line dialysate generator, and a second dialysate pump in fluid communication with the on-line dialysate generator. The dialysis system also includes a dialyzer in fluid communication with the first and second dialysate pumps. The dialysis system further includes a first valve located between the first dialysate pump and the dialyzer and a second valve located between the second dialysate pump and the dialyzer. The dialysis system is configured to alternate pumping of dialysate from the first and second dialysate pumps to the dialyzer using the first and second valves.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: January 22, 2019
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din
  • Patent number: 10183110
    Abstract: The invention relates to a method and a device for monitoring a vascular access during an extracorporeal blood treatment. The method and the device according to the invention are based on the monitoring of the difference between the venous pressure measured by a venous pressure sensor and the arterial pressure measured by an arterial pressure sensor (in the extracorporeal blood circuit. According to the method and the device according to the invention, a test function describing disturbances in the extracorporeal blood circuit is determined. Said test function is used to determine a noise-free differential pressure from the measured venous and arterial pressure, said differential pressure being evaluated in an arithmetic and evaluation unit to identify a defective vascular access.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: January 22, 2019
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Pascal Kopperschmidt
  • Patent number: 10183111
    Abstract: A needle system and methods for using the needle system are described. The needle system is generally intended for medical use and can be used when performing a dialysis on a patient, for example, hemodialysis. In general, the needle system can address problems that commonly arise when using conventional single or double needle systems during hemodialysis.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: January 22, 2019
    Inventor: Amit Shah
  • Patent number: 10183112
    Abstract: A trans-anal irrigation (TAI) system adapted for self-use includes an irrigation head supplied with water from a reservoir by a pump or by gravity feed. The irrigation head has either internal or external structures for releasably retaining the head in a user's rectum during the water flow portion of a TAI process. A guide member arm may be provided for manipulating the irrigation head for both insertion and removal. The irrigation head is reliably attached to the guide member arm. The guide member arm may include an integral manual pump.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: January 22, 2019
    Assignee: Hollister Incorporated
    Inventors: Adam J. Foley, Stephen Collum, David Hannon
  • Patent number: 10183113
    Abstract: A dosing unit for an ambulatory infusion system, including a metering pump unit including a dosing cylinder and a piston, the piston in sealing sliding engagement inside the dosing cylinder; a valve unit having a filling port and a draining port, the filling port being couplable with a liquid drug reservoir, the draining port being couplable with an infusion site interface, and a shut-off body movable between a filling position where it couples the filling port with the dosing cylinder and a draining position where it couples the dosing cylinder with the draining port; and a valve driver coupler coupled to or integral with the shut-off body and being the output element of a step switching mechanism. Also disclosed is a drive unit that may be used in combination with a dosing unit, an ambulatory infusion system and a method for coupling a dosing unit and a drive unit.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: January 22, 2019
    Assignee: ROCHE DIABETES CARE INC.
    Inventor: Hans List
  • Patent number: 10183114
    Abstract: The present invention relates to an apparatus and a system for controlling an amount of medicine or fluid injection through falling due to potential energy of the fluid. For example, the present invention can automatically adjust an injection rate of a medicine injected into a patient by controlling an opening/closing degree of a medicine hose by using a driving element driven by electric power according to a comparison of the number of drops with a predetermined value. An apparatus for realizing the method includes an accommodating case for accommodating a connecting portion for connecting a fluid, a detection unit for detecting the number of drops, a control unit for comparing the information detected by the detection unit, and a driving element for opening and closing a passage of the medicine hose based on the contents analyzed by a control unit.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: January 22, 2019
    Assignee: ACE MEDICAL CO., LTD.
    Inventor: Jong-Woo Lee
  • Patent number: 10183115
    Abstract: Disclosed is a syringe for corium regeneration. The syringe includes a cylinder formed as a thin tube having an inner diameter of 2-7 mm such that a liquid can be separated and stacked over a gas inside the cylinder; an inflow check valve provided on one side of the lower end of the cylinder such that a gas, which is supplied from the outside, can flow into the cylinder; and a needle coupled to the lower end of the cylinder, the upper end of the needle being positioned between a point which is 2 mm below the portion of connection of the inflow check valve and a point which is 5 mm above the portion of connection of the inflow check valve.
    Type: Grant
    Filed: February 2, 2015
    Date of Patent: January 22, 2019
    Inventors: Joong Suk Jin, Se Hoon Chin
  • Patent number: 10183116
    Abstract: An apparatus includes a housing, a medicament container, and a movable assembly. The movable assembly includes a first movable member and a second movable member. The second movable member is configured to move relative to the first movable member to move the movable assembly from a first configuration to a second configuration. A distal end portion of the second movable member is configured to move a plunger disposed within the medicament container in a distal direction when the movable assembly is moved to the second configuration. The movable assembly is configured to move between a first position and a second position to move the medicament container within the housing between a first container position and a second container position.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: January 22, 2019
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, Frank E. Blondino
  • Patent number: 10183117
    Abstract: A wearable automatic injection device is provided for administering a final medicament to a patient. The wearable automatic injection device comprises a housing, an injection assembly for injecting the patient with the final medicament, a container holding a bulk intermediate medicament and a diluent to be mixed to form the medicament, and a mixing mechanism for mixing the bulk intermediate medicament and the diluent in the container to form the final medicament prior. A system for administering a final medicament to a patient is also provided. The system comprises a container, a mixing mechanism for mixing a bulk intermediate medicament and a diluent in the container to form the final medicament, and a wearable automatic injection device configured to receive the container.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: January 22, 2019
    Assignee: AbbVie Inc.
    Inventors: Wolfgang Fraunhofer, James Cameron, Linas P. Laurusonis
  • Patent number: 10183118
    Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: January 22, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Michael Vincent Quinn, Eric Schiller, Gang Ju, E Guan
  • Patent number: 10183119
    Abstract: An add-on dose logging device for a pen device consumes energy when the sensors are operated and when the display is active. By using cap-off event to activate the sensor system only, and using cap-on event to de-activate the sensor system and activate the display for a given time to display a sensed dose, power consumption can be reduced without changing the user-interface and without adding any components apart from a switch.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: January 22, 2019
    Assignee: Novo Nordisk A/S
    Inventors: Jens Christian Andersen, Nikolaj Frogner Krusell, Claus Bagger
  • Patent number: 10183120
    Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: January 22, 2019
    Assignee: Common Sensing Inc.
    Inventors: Kevin Sihlanick, Richard Whalley, Matthew Legrand, James White, Jeffrey Carothers
  • Patent number: 10183121
    Abstract: An injection device is disclosed which comprise a housing (10), a plunger (40) for expressing a medicament from a syringe (20) and an actuation mechanism (30). The actuation mechanism (30) is arranged in use to move the plunger (40) between a first rearward position and a second forward position to express a dose from the syringe (20). The injector device further comprises an injection activation sensor 51, arranged for example to provide an end of dose indication. The sensor 51 comprises an elongate flexible member (50). The flexible member (50) has a first end (52) connected to the plunger (40) or actuation mechanism (30) such that actuation motion of the injection device acts to move the elongate flexible member (50) relative to the housing. Movement of the elongate member (50) triggers a response to the injection such as an audible and/or tactile injection complete indication.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: January 22, 2019
    Assignee: OWEN MUMFORD LIMITED
    Inventor: Toby Cowe
  • Patent number: 10183122
    Abstract: A fluid injection device having a syringe body, a needle, and a needle protection device. The protection device includes a substantially flexible or deformable inner body and a substantially rigid outer body. The inner body closes a dispenser orifice of the needle, and co-operates with the syringe body in a leaktight manner, and the outer body fastens the protection device on the syringe body. The inner body includes a radial projection, and the outer body includes a radial shoulder and an axial end edge that defines a top axial opening. The inner body is inserted in the outer body, through the top axial opening, with the radial projection in abutment against the radial shoulder, the axial end edge of the outer body folded down on the inner body so as to fasten the inner body in the outer body.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: January 22, 2019
    Assignee: APTAR STELMI SAS
    Inventors: Arnaud Fournier, Ghislain Fournier, Mickael Swal
  • Patent number: 10183123
    Abstract: Injection device of fluid product (100) comprising a syringe body (101) and a needle (110) fixed in an axial end projection (102) of the syringe body, said end projection (102) comprising an axial end surface (103), said injection device comprising a needle protection device (200), said protection device being, in a storage position, fixed on said injection device, said protection device being removable from said injection device, said protection device comprising an inner body (210) made of substantially supple and/or deformable material and an outer body (220) made of substantially rigid material, said inner body (210), in a storage position, sealingly closing the distribution orifice (111) of said needle (110) and sealingly cooperating with said injection device (100), and said outer body (220) comprising a fixing part (228) which, in a storage position, cooperates with a shoulder (104) of said injection device (100) for fixing said protection device (200) on said injection device (100), said inner body (2
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: January 22, 2019
    Assignee: APTAR STELMI SAS
    Inventors: Arnaud Fournier, Ghislain Fournier, Mickaël Swal
  • Patent number: 10183124
    Abstract: Provided is a system and method for an ergonomic needle protector. More specifically, provided is an ergonomic needle protector for a needle having a first curvature. The ergonomic needle protector has a flexible body having a first end and a second end, and an internal channel extending from the first end towards the second end. The flexible body is formed of a resilient material structured and arranged to return to a curved state along the length of the flexible body according to a second curvature different from the first curvature of the needle. The internal channel is structured and arranged to receive the needle when the flexible body is deformed to conform the internal channel to the first curvature and frictionally bind against the needle when the flexible body is released back to the second curvature. An associated method of use is also provided.
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: January 22, 2019
    Inventors: Andrew I. Sealfon, Siavash Gheshmi
  • Patent number: 10183125
    Abstract: A puncture device includes a housing unit including an attachment surface configured to be attached to a body surface of a user; a puncture needle including an outer needle and an inner catheter located in the outer needle, the puncture needle being configured to be projected from the attachment surface to be punctured into a body of the user; a puncture mechanism configured to project the puncture needle from the attachment surface to be punctured into the body of the user, and pull back only the outer needle of the puncture needle into the housing unit with the inner catheter of the puncture needle indwelled in the body; and a puncture angle adjustment mechanism configured to adjust a puncture angle of the puncture needle, which is an angle of the puncture needle with respect to the attachment surface.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: January 22, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Joji Uchiyama
  • Patent number: 10183126
    Abstract: A heated patient tube assembly that carries and warms fluids to a desired temperature includes an elongated hollow tube and a heating assembly at least partially embedded within the tube for heating the tube and fluids carried in the tube. The heated patient tube assembly can be selectively used in any combination of three different modes: a first mode in which the heating assembly is connected to a control assembly, a second mode in which the heating assembly is powered wirelessly, and a third mode in which the tube is inserted into and heated by an external warming device.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: January 22, 2019
    Inventors: Scott Norman, Mark Petheram, Anthony Hash
  • Patent number: 10183127
    Abstract: The present invention relates to a pressure reducer for delivering drugs to a patient and the corresponding method of manufacture, said pressure reducer for delivering drugs to a patient comprising: a duct (9) with an inlet (11) and an outlet (13), a first body (1) with a first surface (5), and a second body (3) with a second surface (6) directly contacting the first body (1). One of the surfaces (5,6) has a recess (7) such that a duct (9) is defined between both surfaces. Both bodies are attached to one another by means of a continuous attachment line running on both sides of the duct (9). The method of manufacture comprises a laser welding step in which the first body (1) is welded to the second body (3) by means of a welding seam extending along both sides of the duct.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: January 22, 2019
    Assignee: LEVENTON S.A.U.
    Inventors: Jordi Martín Llorens, Javier Torras Marí
  • Patent number: 10183128
    Abstract: An injection device for injecting liquid medicine to a patient comprises a medicine container (2) an end of which is connectable to a needle (3) and magnetic sensor means (21, 22) for sensing connection of the needle (3) to the medicine container (2).
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: January 22, 2019
    Assignee: ARES TRADING SA
    Inventors: Werner Wurmbauer, Josef Schopf, Bernhard Schatz
  • Patent number: 10183129
    Abstract: A closure assembly structured for use with a female connector and being operative to indicate an attempted tampering or access thereto. A flow restrictor is movably and removably disposed within a housing and includes a male connector such as, but not limited to, a male luer connector comprising a plug disposed and structured to be inserted in flow restricting engagement within an interior port of the female connector. An indicator member is removably connected to an interior of the housing in surrounding relation to the flow restrictor and a drive assembly associated with both the flow restrictor and the housing is operable to dispose the male plug into the inserted, flow restricting engagement within the female connector. Attempted removal of the housing from the female connector, such as by an applied axial force, will detach the indicator member from the housing and expose it in a visually observable position on the flow restrictor, thereby indicating attempted access.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: January 22, 2019
    Assignee: MEDICAL DEVICE ENGINEERING, LLC
    Inventor: Jonathan J. Vitello
  • Patent number: 10183130
    Abstract: A medical fluid infusion system includes a pump system configured to deliver a fluid drug to a patient. The system includes a pump, such as a piston pump, for driving fluid to a patient. One or more pressure sensors are configured to measure and detect changes in fluid pressure in a fluid flow line of the infusion system. The changes in fluid pressure, when detected, can be an indication of proper or improper functioning of a valve system of the pump system of the fluid infusion system.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: January 22, 2019
    Assignee: CareFusion 303, Inc.
    Inventors: Daniel Kimm, Lee Good, Alexander Ellington
  • Patent number: 10183131
    Abstract: An extraction system uses a sample of botanical matter which has been rendered into particles of a predetermined range of sizes and compressed into a non-flowable form. The sample is loaded into an extraction chamber which may be sealed. A conductive or convective heat source is used to heat the loaded sample to a temperature which causes at least one substance within the sample to vaporize. A conduit can be used to transfer vapor resulting from vaporization of the substance to a collection chamber and mask. Pressure may be adjusted within the system to facilitate vaporization and vapor transport.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: January 22, 2019
    Inventor: Jeffrey M. Skell
  • Patent number: 10183132
    Abstract: The present invention is directed to an integrated delivery device that is operable with one hand and provides co-delivery of a liquid medicant and a powder medicant onto a tissue or wound from a liquid medicant expression subunit and a powder medicant expression subunit. Each expression subunit having an actuator for the liquid medicant and the powder medicant contained therein that are positioned in close proximity to one other at a proximate end of said expression subunits and delivery cannulas for each of said expression subunits that positioned in close proximity to one other at a distal end of said expression subunits. The present invention also relates to method for using such integrated devices.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: January 22, 2019
    Assignee: Ethicon LLC
    Inventors: Yi-Lan Wang, Leo B. Kriksunov
  • Patent number: 10183133
    Abstract: An inhaler comprising a housing defining a chamber to receive a strip having a plurality of blisters each containing a dose of medicament for inhalation by a user is disclosed.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: January 22, 2019
    Assignee: VECTURA DELIVERY DEVICES LIMITED
    Inventors: Andreas Meliniotis, Andrew Solly, Roger Clarke, Liam McGuinness
  • Patent number: 10183134
    Abstract: An MIE apparatus has a blower, a valve system, and a mask hose connector. The blower is connected to the valve system which is connected to the hose connector. During insufflation, the valve system connects exhaust of the blower to the hose connector to cause positive pressure at the hose connector. During exsufflation, the valve system connects the blower intake to the hose connector to cause negative pressure at the hose connector. The apparatus has an automatic mode in which switching between insufflation and exsufflation is based on one or more preset time intervals and a manual mode in which switching between insufflation and exsufflation is based on a manual input from a user.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: January 22, 2019
    Assignee: Hill-Rom Services Pte. Ltd.
    Inventors: Christopher Ikei, Dano S. Carbone, Lewis W. Ward, Tammy Stultz
  • Patent number: 10183135
    Abstract: A respiratory assistance device is disclosed. There is a patient interface for coupling to a patient respiratory passageway, and a selectively regulated therapeutic gas flow source in pneumatic communication with the patient over the patient interface. A controller is connected to the therapeutic gas flow source and is receptive to inputs of a prescription pressure level and an initial delay duration. After the patient dons the patient interface, therapeutic gas flow is restricted for the initial delay duration following receipt of a treatment initiation command. Upon the expiry of the initial delay duration, the controller increases therapeutic gas flow to the prescription pressure level.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: January 22, 2019
    Assignee: Breathe Technologies, Inc.
    Inventors: Samir S. Ahmad, Leonardo Alberto Baloa-Welzien
  • Patent number: 10183136
    Abstract: CPAP treatment apparatus is disclosed having a controllable positive airway pressure device. A sensor generates a signal representative of patient respiratory flow that is provided to a controller. The controller is operable to determine the occurrence of an apnea from a reduction in respiratory airflow below a threshold determined from long term ventilation. When an apnea or hypopnea has occurred the calculation of the threshold is suspended until the end of that event.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: January 22, 2019
    Assignee: ResMed Limited
    Inventors: Matthew Alder, Steven Paul Farrugia, Chinmayee Somaiya
  • Patent number: 10183137
    Abstract: A respiratory interface device is provided. The respiratory interface device includes a cushion structured to be coupled to a faceplate that includes a peripheral end and a coupling assembly. The faceplate peripheral end includes a formable material and a portion of faceplate peripheral end is a customized contoured end. Cushion is coupled to faceplate adjacent faceplate customized contoured end, cushion conforming to faceplate customized contoured end.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: January 22, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Lauren Patricia Chodkowski, Robert William Baiko
  • Patent number: 10183138
    Abstract: A system of breathing arrangements for delivering breathable gas to a patient includes at least first and second cushion components, e.g., full-face, nasal, nasal prongs, nose tip, and/or a combination of any of the above, including a nasal or full-face cushion and nasal prongs/nozzles combination, etc., that are different from one another in at least one aspect, and a common frame assembly configured to support each of the first and second cushion components. Various embodiments are directed to a full-face or nasal mask used with a frame having lateral connector portions having a stiffening member. The mask assembly may include a nose height adjustment device for the height of the cushion, or a cushion adjustment member by which the position of the cushion may be adjusted relative to the frame. The mask assembly may include a chin strap assembly.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: January 22, 2019
    Assignee: ResMed Limited
    Inventors: Eva Ng, Robert Edward Henry, Philip Rodney Kwok, Karthikeyan Selvarajan
  • Patent number: 10183139
    Abstract: A method for controlling mechanical lung ventilation is described. The method may include supplying a breathing gas to an airway of a patient in an intermittent way such that a plurality of respiratory cycles are formed; measuring a volume received by the patient in one or more respiratory cycles of the plurality of respiratory cycles; comparing the measured volume of each of the one or more respiratory cycles with a user defined target volume; attributing a classifying score to each of the one or more respiratory cycles based at least partially on a deviation between the measured volume and the user defined target volume; summing the classifying scores and dividing the result by a sample size of the one or more respiratory cycles; attributing a pressure step value based at least partially on the division result; and adding the pressure step value to a present pressure.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: January 22, 2019
    Assignee: Vyaire Medical Capital LLC
    Inventors: Jorge Bonassa, Adriano De Lima Santos, José Augusto Calvo Lonardoni, Tito Coutinho Melco
  • Patent number: 10183140
    Abstract: The present invention relates to an apparatus and a method for local anesthesia and, more specifically, to an apparatus and a method for local anesthesia, which precisely indicate an anesthesia region and enable injection to be administered around the anesthesia region through a plurality of anesthesia needles. According to the present invention, the fear and pain of a subject to be anesthetized can be reduced since the affected part of the subject to be anesthetized can be anesthetized by injecting a plurality of syringes all at once, and an injection can be precisely administered to a region at which an injection is to be administered since the affected part can be precisely indicated by a provided laser pointer.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: January 22, 2019
    Assignees: AJOU UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION, UNIVERSITY—INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Kilyeon Lee, Moongu Lee, Yongho Jeon, Jaeseung Kim
  • Patent number: 10183141
    Abstract: The present disclosure provides systems and methods for at least one of preventing, reducing, and treating a level of or change in at least one of amyloid-? (A?) peptide, C-terminal fragment-? (?-CTF), ?-secretase (BACE1), ?-secretase, neuroinflammation, and/or dementia (e.g., Alzheimer's disease or age-related decline) in a subject by inducing synchronized gamma oscillations in the brain of the subject using, for example, a stimulus-emitting device to emit a stimulus (e.g., light, sound, and/or haptic) at a frequency (e.g., about 40 Hz) that synchronously activates in vivo a specific cell type (e.g., fast-spiking-parvalbumin (FS-PV) immunoreactive interneurons) and/or brain region (e.g., a sensory cortex and/or hippocampus) of the subject.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: January 22, 2019
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Li-Huei Tsai, Emery Brown, Hannah Iaccarino, Anthony James Martorell, Chinnakkaruppan Adaikkan
  • Patent number: 10183142
    Abstract: The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on cardiac activity in the subject during the sleep session. Cardiac activity, as monitored via one or more sensors worn on an extremity of the subject and/or placed at a distance from the subject, is used to determine periods of slow wave sleep. Sensory stimulation is delivered to the subject during the periods of slow wave sleep to enhance slow wave activity. Wearing a sensor on an extremity, and/or placing a sensor at a distance from the subject during sleep, as opposed to the subject wearing an EEG cap, is more comfortable for the subject.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: January 22, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Gary Nelson Garcia Molina, Cristian Nicolae Presura, Stefan Pfundtner, Sander Theodoor Pastoor
  • Patent number: 10183143
    Abstract: An implantable occlusion and tissue ingrowth resistant fluid interface is provided with a housing, an orifice and a catheter port. The housing is formed from at least one biocompatible material and is configured without sharp edges or corners. The housing at least partially defines an internal housing cavity. The orifice member at least partially defines an orifice between the internal housing cavity and an exterior of the housing. The orifice has an elongated transverse cross-section configured with a length that is at least four times its maximum width. The catheter port is located on the housing and is configured to couple with a catheter such that the internal housing cavity is in fluid communication with a lumen of the catheter when the catheter is coupled to the catheter port. Embodiments having a moving cylinder, a rotor, and non-chemical surface modifications, as well as methods of use are also disclosed.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: January 22, 2019
    Assignee: Bitol Designs, LLC
    Inventors: Ashik A. Mohan, Avinash L. Mohan, Mark J. Bernhard
  • Patent number: 10183144
    Abstract: A device disclosed herein includes a tubular member which is flexible and configured to receive ultraviolet (UV) light from a UV illumination coupler. The tubular member contains a lumen defining a longitudinal interior space within the tubular member, a tubular body bounded by an inner wall defining an outer boundary of the lumen and an outer wall defining an outer surface of the tubular member, at least one optical fiber disposed outside of the interior space not parallel to an axis of the lumen and adapted to receive the UV light from the UV illumination coupler, and a protective component adapted to prevent substantively all of the UV light emitted from the optical fiber from exiting the outer wall. Methods for producing and using such devices are also disclosed herein.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: January 22, 2019
    Assignees: The University of Maryland, Baltimore, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Cha-Min Tang, Paul E. Bigeleisen, Samuel M. Galvagno, Jr., Mark E. Shirtliff
  • Patent number: 10183145
    Abstract: A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: January 22, 2019
    Assignee: Incept, LLC
    Inventors: Yi Yang, Fred Khosravi, Lisa M. Young
  • Patent number: 10183146
    Abstract: A method of making a high flexibility distal zone on a neurovascular catheter is provided. The method includes the steps of dip coating a removable mandrel to form a tubular inner layer on the mandrel, coating the tubular inner layer with a soft tie layer, applying a helical coil to the outside of the tie layer, positioning a plurality of tubular segments on the helical coil, heating the tubular segments to form the high flexibility distal zone on the neurovascular catheter; and removing the mandrel. The plurality of segments have durometers that decrease in a distal direction. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: January 22, 2019
    Assignee: Incept, LLC
    Inventors: Yi Yang, Fred Khosravi, Lisa M. Young
  • Patent number: 10183147
    Abstract: A neurovascular catheter extension segment is provided, such as for distal neurovascular access or aspiration. The neurovascular catheter extension segment includes 1) an elongate flexible control wire having a proximal end and a distal end and 2) a tubular extension segment having a side wall defining a central lumen carried by the distal end of the control wire. The side wall of the tubular extension segment includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, and an outer jacket surrounding the helical coil. The extension segment may be introduced into the proximal end of a neurovascular catheter and advanced distally to extend beyond the catheter and thereby extend the reach of the catheter.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: January 22, 2019
    Assignee: Incept, LLC
    Inventors: Yi Yang, Fred Khosravi, Lisa M. Young
  • Patent number: 10183148
    Abstract: A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.
    Type: Grant
    Filed: July 20, 2014
    Date of Patent: January 22, 2019
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Randall Moshinsky, James McMillan, Elli Tutungi
  • Patent number: 10183149
    Abstract: Catheter ultrasound systems including a sheath, a handle, a sheath lumen, and an ultrasound catheter disposed within the lumen of the sheath with ultrasound elements capable of visualizing anatomical regions. The handle allowing the ultrasound catheter to rotate with respect to the sheath using a rotation adjustment knob within the handle or alternatively an separate manipulation handle attached to the proximal end of the ultrasound catheter. The sheath, ultrasound catheter, or both may also include one or more electrodes or other location sensor for both orienting the ultrasound element as well as for diagnostic purposes.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 22, 2019
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventors: Troy Terrance Tegg, Andrew Senn, James V. Kauphusman, Michael C. Bednarek