Patents Issued in January 24, 2019
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Publication number: 20190023806Abstract: The present disclosure in some aspects relates to hemoglobin (including various hemoglobin variants) polypeptides. In some aspects, the present disclosure further relates to hemoglobin antibodies, including camelid antibodies that specifically bind to hemoglobin, and antibody fragments. The disclosure further relates to methods of detecting an analyte in a sample using a camelid antibody, such as a camelid VHH antibody or fragments thereof. In one aspect, provided herein is a technology platform for isolating highly specific antibodies and applying these antibodies in an immunoassay, such as a lateral flow immunoassay (LFIA). In some aspects, this technology is used to develop hemoglobin variant specific antibodies and to produce LFIA devices for rapid and early diagnosis of a disease.Type: ApplicationFiled: October 20, 2016Publication date: January 24, 2019Applicant: QOOLABS, INC.Inventor: Hong QI
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Publication number: 20190023807Abstract: The disclosure relates to binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.Type: ApplicationFiled: January 12, 2017Publication date: January 24, 2019Inventors: Eleanora Balloi, Normann Goodwin, Brian McGuinness, Chris Rossat, Thomas Sandal, Lorraine Thompson
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Publication number: 20190023808Abstract: An antibody recognizing the O-acetylated-GD2 ganglioside for the treatment of Cancer Stem Cells (CSC) cancer, a pharmaceutical composition including the antibody for treating a CSC cancer and a method for treating a CSC cancer in a patient in need thereof, the method including administering the antibody to the patient. A method for diagnosing a CSC, the use of the O-acetylated-GD2 ganglioside as a biomarker of CSC cancer, and a method for predicting the response of a subject affected with CSC cancer to a treatment with the antibody or the composition are also described.Type: ApplicationFiled: May 21, 2018Publication date: January 24, 2019Inventors: Stephane BIRKLE, Denis COCHONNEAU, MyIene DORVILLIUS, Jean-Marc LE DOUSSAL, MickaeI TERME
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Publication number: 20190023809Abstract: The present disclosure provides anti-NAMPT cDNA clones and the amino acid sequences encoded by the clones. Such clones and amino acid sequences are combinable in several variations and can be used to decrease NAD synthesis in a targeted cell population.Type: ApplicationFiled: September 6, 2016Publication date: January 24, 2019Inventors: Shui Qing Ye, Daniel P. Heruth, Li Qin Zhang
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Publication number: 20190023810Abstract: Described herein are mutations in the CHl/CL interface and CH3 constant regions of a bispecific antibody which facilitate heterodimerization and methods for the efficient production of bispecific antibodies. Also disclosed are therapeutic and diagnostic methods for using the antibodies.Type: ApplicationFiled: December 28, 2016Publication date: January 24, 2019Applicants: Massachusetts Institute of Technology, Massachusetts Institute of TechnologyInventors: Ram SASISEKHARAN, Kannan THARAKARAMAN, Vidya SUBRAMANIAN, Eduardo FLEISCHER, Andrew Peter HATAS
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Publication number: 20190023811Abstract: The present invention provides a method of preparing a dry biocellulose material, including immersing a biocellulose material into an aqueous solution containing 10% or a higher concentration of glycerol for a predetermined time, and drying the biocellulose material containing glycerol. The present invention also provides a dry biocellulose material prepared thereby. The preparation method of the present invention prevents irreversible impairment to the fibrous structure of the biocellulose material due to drying at high temperatures. Thus, the dry biocellulose material of the present invention may quickly regain a condition of high water content after contact with water.Type: ApplicationFiled: July 19, 2018Publication date: January 24, 2019Inventors: Yung-Hsiang Lin, Cheng-Yu Ho, Wei-Hsiu Chuang
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Publication number: 20190023812Abstract: The invention relates to a hydrogel product comprising glycosaminoglycan molecules as the swellable polymer, wherein the glycosaminoglycan molecules are covalently crosslinked via crosslinks comprising a spacer group selected from the group consisting of di-, tri-, tetra-, and oligosaccharides.Type: ApplicationFiled: December 28, 2016Publication date: January 24, 2019Applicant: GALDERMA S.A.Inventors: Hotan MOJARRADI, Johan OLSSON, Craig Steven HARRIS, Jean-Guy BOITEAU, Thibaut GERFAUD, Loïc TOMAS
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Publication number: 20190023813Abstract: A process is described for the purification of HA, and pharmaceutical, cosmetic and nutritional compositions containing HA thus purified.Type: ApplicationFiled: July 17, 2018Publication date: January 24, 2019Applicant: FIDIA FARMACEUTICI S.P.A.Inventors: Vincenza CORSA, Giancarlo CARPANESE
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Publication number: 20190023814Abstract: Disclosed are compositions comprising a liquid carrier, a polysulfide rubber curing agent, a metal cation, and an ionic liquid. Also disclosed are methods for curing a surface of an uncured polysulfide rubber. These methods involve applying the disclosed compositions to the surface of the uncured polysulfide rubber.Type: ApplicationFiled: November 6, 2017Publication date: January 24, 2019Inventors: Matthew Alexander Flack, Andrew M. Zweig
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Publication number: 20190023815Abstract: Provided is a method of preparing a rubber composition, which includes (a) reacting a conjugated diene-based monomer with one or more of compounds in the presence of a first catalyst; (b) adding a conjugated diene-based monomer to a product of the step (a) and inducing a reaction; and (c) adding a second catalyst and a conjugated diene-based monomer to a product of the step (b) and inducing a reaction.Type: ApplicationFiled: July 12, 2018Publication date: January 24, 2019Inventors: Jae Yun KIM, Yeong Min JUNG
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Publication number: 20190023816Abstract: The invention relates to: a hybrid supported metallocene catalyst includes at least one first metallocene compound among the compounds represented by chemical formula 1, at least one second metallocene compound among the compounds represented by chemical formula 2 and a cocatalyst compound; a method for preparing an ethylene-?-olefin copolymer, comprising polymerizing olefin monomers in the presence thereof; and an ethylene-?-olefin copolymer having improved melt strength.Type: ApplicationFiled: March 29, 2016Publication date: January 24, 2019Applicant: HANWHA CHEMICAL CORPORATIONInventors: Ah Ra Cho, Ah Reum Kim, Lan Hua Piao, Jun Ho Seo, Song Hee Yang, So Jung Lee, Yu Jeong Lim, Dong Wook Jeong, Seung Il Choi
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Publication number: 20190023817Abstract: A method for synthesizing a piezoelectric material is provided. The method includes dehydrofluorinating a fluoropolymer precursor by incubating the fluoropolymer precursor in the presence of a base, wherein the fluoropolymer precursor comprises poly(vinylidene fluoride) or a copolymer of vinylidene fluoride; and isolating an at least partially dehydrofluorinated fluoropolymer solid having ?-phase and that exhibits melt flow processability at a temperature of greater than or equal to about 150° C. The at least partially dehydrofluorinated fluoropolymer solid is capable of forming a solid piezoelectric fluoropolymer material having ?-phase in an amount sufficient to exhibit a piezoelectric strain coefficient d31 absolute value of greater than or equal to about 25 pm/V.Type: ApplicationFiled: August 15, 2018Publication date: January 24, 2019Inventor: Henry A. Sodano
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Publication number: 20190023818Abstract: The invention provides a method for producing low molecular weight polytetrafluoroethylene less likely to generate C8-C14 perfluorocarboxylic acids and salts thereof. The method for producing low molecular weight polytetrafluoroethylene includes: (1) feeding into an airtight container: polytetrafluoroethylene; at least one additive selected from the group consisting of hydrocarbons, chlorinated hydrocarbons, alcohols, and carboxylic acids other than C8-C14 perfluorocarboxylic acids; and at least one selected from the group consisting of inert gases other than the above additive and oxygen adsorbents; and (2) irradiating the polytetrafluoroethylene to provide low molecular weight polytetrafluoroethylene having a complex viscosity of 1×102 to 7×105 Pa·s at 380° C.Type: ApplicationFiled: August 4, 2017Publication date: January 24, 2019Applicant: DAIKIN INDUSTRIES, LTD.Inventors: Ken YOSHIDA, Hirotoshi YOSHIDA, Keisuke HAGI, Masayuki TSUJI, Taketo KATO, Yuuji TANAKA, Taku YAMANAKA, Kazuya KAWAHARA, Masamichi SUKEGAWA, Kazutaka HOSOKAWA
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Publication number: 20190023819Abstract: Thermally or electrically conductive high molecular weight polyethylene compositions are disclosed. The polymer compositions can contain thermally conductive particulate material, such as boron nitride. Alternatively or in addition, the polymer composition may contain a thermally and electrically conductive material, such as an ionic liquid or graphite particles.Type: ApplicationFiled: July 20, 2018Publication date: January 24, 2019Inventors: Christina Schmid, Rainer Walkenhorst
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Publication number: 20190023820Abstract: It is intended to provide a method for producing a catalyst for olefin polymerization which exhibits excellent catalytic activity in a polymerization treatment and permits production of a polymer excellent in stereoregularity, melt flowability, etc., even when the polymerization catalyst is prepared in an inert gas atmosphere by using a solid catalytic component comprising an electron-donating compound other than a phthalic acid ester. The method for producing a catalyst for olefin polymerization comprises performing a pre-contact treatment of bringing a solid catalytic component (A) comprising a magnesium atom, a titanium atom, a halogen atom and an electron-donating compound having no phthalic acid ester structure, a specific organoaluminum compound (B) and an external electron-donating compound (C) into contact with each other at a temperature of lower than 15° C. for a time of 30 minutes or shorter in the absence of the olefin.Type: ApplicationFiled: October 28, 2016Publication date: January 24, 2019Applicant: TOHO TITANIUM CO., LTD.Inventors: Hiroyuki Kono, Takahiro Masuyama, Shinta Marui, Toshiya Uozumi
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Publication number: 20190023821Abstract: Essentially ETU-free cross linkable compositions comprising chloroprene rubber, a cross-linker and a vulcanization accelerator, which have a defined content of ions from the second or third main group and resinate anions and thus possesses improved curing characteristics, a process for vulcanization of such compositions and vulcanizates obtained thereby.Type: ApplicationFiled: November 25, 2016Publication date: January 24, 2019Applicant: ARLANXEO DEUTSCHLAND GMBHInventors: VICTOR NASREDDINE, HEINER STANGE, NICOLAS SARY, MARTIN SCHNEIDER, KAY VARNHORN
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Publication number: 20190023822Abstract: Methods for determining the concentration of transition metal compounds in a solution containing more than one transition metal compound are described. Polymerization reactor systems providing real-time monitoring and control of the concentrations of the transition metal components of a multicomponent catalyst system are disclosed, as well as methods for operating such polymerization reactor systems.Type: ApplicationFiled: June 5, 2018Publication date: January 24, 2019Inventors: Qing Yang, Richard M. Buck
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Publication number: 20190023823Abstract: Disclosed herein is a method for reducing isomerization during the copolymerization of ethylene with an ?-olefin comprising adding to a reactor a reaction mixture comprising hydrogen, ethylene, an ?-olefin, a solvent and a catalyst; where the catalyst does not include a chain shuttling agent that comprises dialkyl zinc; heating the reactor to a first temperature to react the ethylene with the ?-olefin to form a copolymer; discharging from the reactor a first product stream to a heat exchanger; where the product stream comprises the copolymer; adding to the product stream prior to the heat exchanger a first additive that is operative to reduce isomerization of the ?-olefin; and discharging from the heat exchanger a second product stream.Type: ApplicationFiled: December 14, 2016Publication date: January 24, 2019Inventors: Daniela Ferrari, Sean Ewart, Timothy Gambrel
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Publication number: 20190023824Abstract: Star polymer occlusion complexes were prepared comprising i) an amphiphilic unimolecular star polymer having a crosslinked core covalently linked to 6 or more independent amphiphilic polymer arms, ii) a nutraceutical (such as coenzyme Q10), and iii) a cholesterol-lowering drug (such as simvastatin). An initial occlusion complex formed with the nutraceutical and the star polymer exhibited improved binding properties for the cholesterol-lowering drug, resulting in improved loading efficiencies for the cholesterol-lowering drug. The star polymer occlusion complexes have utility in the medical treatment of high blood cholesterol.Type: ApplicationFiled: July 20, 2017Publication date: January 24, 2019Inventors: Mohd Zulkefeli Bin Mat Jusoh, Alshakim Nelson, Victoria A. Piunova, Joseph Sly
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Publication number: 20190023825Abstract: The present invention relates generally to a polyvinyl alcohol composition having higher amorphous polyvinyl alcohol polymer content and various end uses thereof.Type: ApplicationFiled: September 24, 2018Publication date: January 24, 2019Applicant: KURARAY CO., LTD.Inventors: Michael Collins, Ghebrehiwet Ghebremeskel, Masaki Kato, Keisuke Morikawa, Yoriko Imaoka
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Publication number: 20190023826Abstract: The invention relates to a specific copolymer obtainable by co-polymerizing at least the following monomers: —more than 80 wt % of at least one bicyclic (meth)acrylate ester, —0.05 to 15% w/w styrene, and—optionally other ethylenically unsaturated monomers, as well as to the way to synthesize them and the use of such polymers to modify the rheology of a liquid in which they are soluble.Type: ApplicationFiled: February 3, 2017Publication date: January 24, 2019Inventors: John Socrates THOMAIDES, John M. MORALES, Qiwei HE, Damien Christian VADILLO, Michael Timothy PHILBIN
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Publication number: 20190023827Abstract: A composition and methods for making the same. The composition includes an isoolefin having from 4 to 7 carbons, a first styrene, and a second styrene alkylated with a diene to have a pendant double bond. A copolymer having units derived from an isoolefin having from 4 to 7 carbons and an alkylstyrene can be reacted with a diene to provide the composition. The reaction of the copolymer with the diene can be reacted in the presence of a catalyst at a temperature of about 80° C. to about 200° C.Type: ApplicationFiled: May 23, 2018Publication date: January 24, 2019Inventors: Andy H. Tsou, Hillary L. Passino, Jennifer L. Rapp
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Publication number: 20190023828Abstract: A graft copolymer includes: an inner layer made of a hard polymer (I) obtained by polymerizing a monomer mixture including 40 to 100 wt % of a methacrylate ester 0 to 15 wt % of an aromatic vinyl monomer, and 0 to 45 wt % of another copolymerizable monomer and 0.01 to 10 parts by weight of a polyfunctional monomer; an intermediate layer made of a soft polymer (II) obtained by polymerizing a monomer mixture including 60 to 100 wt % of an acrylate ester and 0 to 40 wt % of another copolymerizable monomer, 0.01 to 5 parts by weight of allyl (meth)acrylate, and a di(meth)acrylic compound; and an outer layer made of a hard polymer (III) obtained by polymerizing a monomer mixture including 40 to 100 wt % of a methacrylate ester and 60 to 0 wt % of another copolymerizable monomer and 0 to 10 parts by weight of a polyfunctional monomer.Type: ApplicationFiled: September 21, 2018Publication date: January 24, 2019Applicant: KANEKA CORPORATIONInventors: Mitsuru Nakamura, Fuminobu Kitayama
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Publication number: 20190023829Abstract: Process for the preparation of a novolac alkylphenol resin using a defined mixture of mono- and dialkylphenols, an aldehyde, and an acid catalyst. The mixture of mono- and dialkylphenols comprises 20 to 70 mol % mono-alkylphenols having an alkyl group of 1 to 18 carbon atoms, and 30 to 80 mol % of dialkylphenols having alkyl groups of 1 to 18 carbon atoms. The molar ratio of aldehyde in comparison to the mono- and dialkylphenol mixture is greater than or equal to 1. Novolac alkylphenol resins prepared according to this invention contain, of each individual starting material phenolic monomer component, less than 0.5 mass %, and in the best case, less than 0.1 mass % in comparison to the total obtained alkylphenol resin.Type: ApplicationFiled: March 9, 2017Publication date: January 24, 2019Applicant: SUMITOMO BAKELITE EUROPE N. V.Inventors: WOUTER VANORMELINGEN, BART SCHOOFS, TOM DE SMEDT
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Publication number: 20190023830Abstract: This invention provides durable, low-ice-adhesion coatings with excellent ice-adhesion reduction. Some variations provide a low-ice-adhesion composition comprising a composite material containing at least a first-material phase and a second-material phase that are nanophase-separated on a length scale from 10 nanometers to less than 100 nanometers, wherein the first-material phase and the second-material phase further are microphase-separated on a length scale from 0.1 microns to 100 microns. The larger length scale of separation is driven by an emulsion process, which provides microphase separation that is in addition to classic molecular-level phase separation. The composite material has a glass-transition temperature above ?80° C. The coatings may be characterized by an AMIL Centrifuge Ice Adhesion Reduction Factor up to 100 or more. These coatings are useful for aerospace surfaces and many other applications.Type: ApplicationFiled: September 27, 2018Publication date: January 24, 2019Inventors: Andrew P. NOWAK, April R. RODRIGUEZ, Elena SHERMAN, Adam F. GROSS
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Publication number: 20190023831Abstract: Provided are a resin composition for an acoustic wave probe including, a polymer which has a structural unit having a siloxane bond and a structural unit having a urea bond, an acoustic lens using the same, the acoustic wave probe, acoustic wave measurement apparatus, ultrasound diagnostic apparatus, photoacoustic wave measurement apparatus, and ultrasound endoscope.Type: ApplicationFiled: September 27, 2018Publication date: January 24, 2019Applicant: FUJIFILM CorporationInventors: Yuzo NAGATA, Yoshihiro NAKAI, Shigeki UEHIRA, Atsushi OSAWA
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Publication number: 20190023832Abstract: A resin composition containing: an epoxy resin (A) represented by the following formula (1); and a cyanate compound (B), wherein Ar represents a polycyclic aromatic group, R represents a hydrogen atom or a methyl group, G represents a glycidyl group, and n represents an integer of 0 to 15.Type: ApplicationFiled: September 1, 2017Publication date: January 24, 2019Applicant: MITSUBISHI GAS CHEMICAL COMPANY, INC.Inventors: Shota KOGA, Daisuke UEYAMA, Kentaro TAKANO
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Publication number: 20190023833Abstract: An object of the present invention is to provide an epoxy resin composition capable of forming a cured epoxy resin product that exhibits excellent initial transparency and weatherability and excellent adhesion to various substrates. The present invention relates to an epoxy resin composition containing (A) an epoxy resin, (B) a polycarboxylic anhydride containing a structural unit represented by formula (1), and (C) a specific phosphonium compound wherein A represents a cycloalkylene group and the like, R1 to R10 are identical or different and each represent a hydrogen atom or an optionally substituted C1-10 alkyl group, and two groups of R1 to R10 may be taken together to form a divalent group.Type: ApplicationFiled: January 18, 2017Publication date: January 24, 2019Applicant: NEW JAPAN CHEMICAL CO., LTD.Inventors: Takayuki Nagashimada, Eriko Harada
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Publication number: 20190023834Abstract: Resins comprising nanoparticles formed from ?-conjugated cross-linked polymers are disclosed, together with their methods of manufacture and their applications in light emitting devices.Type: ApplicationFiled: January 18, 2017Publication date: January 24, 2019Inventors: Mark McCairn, Michael Turner, Jair Esquivel Guzman, Benjamin Lidster
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Publication number: 20190023835Abstract: The present specification relates to a copolymer including a first unit represented by Chemical Formula 1; and a second unit represented by Chemical Formula 2, and an organic solar cell including the same.Type: ApplicationFiled: January 16, 2017Publication date: January 24, 2019Inventors: Bogyu LIM, Youngu LEE, Jiyoung LEE, Honggi KIM, Hyojung HEO, Jaechol LEE
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Publication number: 20190023836Abstract: The invention relates to novel compounds containing one or more 1,3-dithiolo[4,5-d]phthalimide (“DTPI”) units, to methods for their preparation preparation and educts or intermediates used therein, to mixtures and formulations containing them, to the use of the compounds, mixtures and formulations as organic semiconductors in organic electronic (OE) devices, especially in organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising these compounds, mixtures or formulations.Type: ApplicationFiled: February 17, 2017Publication date: January 24, 2019Applicant: Merck Patent GmbHInventors: Changsheng WANG, William MITCHELL, David SPARROWE
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Publication number: 20190023837Abstract: Disclosed is a process for the manufacture of a composition comprising PEF; wherein said process polymerizes FDCA and a diol in a polymerization reactor; wherein the polymerization reaction occurs in at least one reactor previously used in a polyester plant to produce said composition comprising PEF.Type: ApplicationFiled: March 20, 2018Publication date: January 24, 2019Applicant: EASTMAN CHEMICAL COMPANYInventors: MESFIN EJERSSA JANKA, KEVIN JOHN FONTENOT, KENNY RANDOLPH PARKER
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Publication number: 20190023838Abstract: Disclosed is a process for the manufacture of a composition comprising PEF; wherein said process polymerizes FDCA and a diol in a polymerization reactor; wherein the polymerization reaction occurs in at least one reactor previously used in a polyester plant to produce said composition comprising PEF.Type: ApplicationFiled: March 20, 2018Publication date: January 24, 2019Applicant: EASTMAN CHEMICAL COMPANYInventors: MESFIN EJERSSA JANKA, KEVIN JOHN FONTENOT, KENNY RANDOLPH PARKER
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Publication number: 20190023839Abstract: Various embodiments relate to biorenewable and water-degradable co-polymers and methods of producing co-polymers that include a plurality of first monomeric units and a plurality of second monomeric units joined by a plurality of hydrolytically-sensitive ester linkages. Each of the plurality of first monomeric units may be derived from a first monomer. The first monomer may be the product of a reaction between itaconic acid and a first amino acid. Each of the plurality of second monomeric units may be derived from a second monomer. The second monomer may be the product of a reaction between itaconic acid and a second amino acid. The co-polymers may be a product of the reaction of the first monomer and the second monomer in the presence of a diol. The co-polymers may have a glass transition temperature of about 50° C. or greater.Type: ApplicationFiled: June 25, 2018Publication date: January 24, 2019Inventors: Stephen Albert MILLER, Pengxu QI
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Publication number: 20190023840Abstract: The purpose of the present invention is to provide a polycarbonate resin which has high fluidity and with which mold fouling such as mold deposits, etc., can be reduced. The polycarbonate resin according to the present invention has a terminal structure represented by general formula (1), and a viscosity-average molecular weight of 10,000-18,000, wherein the contained amount of low-molecular-weight carbonate compounds having a molecular weight of 1,000 or less contained in the polycarbonate resin is less than 1 mass %.Type: ApplicationFiled: February 21, 2017Publication date: January 24, 2019Applicant: MITSUBISHI GAS CHEMICAL COMPANY, INC.Inventors: Yuusuke NII, Shun ISHIKAWA
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Publication number: 20190023841Abstract: A polyalkylene glycol derivative with a minimal impurity content is prepared simply by the steps of reacting a compound having formula (III-I) or (III-II) with an electrophile having formula (IV) in the presence of an optional basic compound, to form a reaction solution containing a compound having formula (V), and passing the reaction solution through a column of cation and anion exchange resins to remove water-soluble impurities, for thereby purifying the desired polyalkylene glycol derivative.Type: ApplicationFiled: July 23, 2018Publication date: January 24, 2019Applicant: Shin-Etsu Chemical Co., Ltd.Inventors: Shiori NONAKA, Yuki SUKA, Yuji HARADA
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Publication number: 20190023842Abstract: In one embodiment, a resist material to be used in an imprint process includes a diluent monomer having a hydroxyl group and at least one functional group selected from a vinyl ether group, an epoxy group and an oxetanyl group. The material further includes a dendrimer having at least two reactive groups for photo-cationic polymerization. The material further includes a photo-acid generator as a polymerization initiator.Type: ApplicationFiled: September 27, 2018Publication date: January 24, 2019Applicant: Toshiba Memory CorporationInventors: Kei KOBAYASHI, Seiji MORITA
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Publication number: 20190023843Abstract: A process for the production of a polyamide is disclosed. The process for production of a polyamide (P) comprises mixing a first mixture (M1), which comprises at least one lactam and at least one catalyst, with a second mixture (M2), which comprises at least one lactam, at least one activator and at least one amine, to give a polymerizable mixture (pM) and then polymerization of the polymerizable mixture (pM) to give the polyamide (P). A polyamide (P) obtainable by the process of the invention is also disclosed, as well as moldings made of the polyamide (P).Type: ApplicationFiled: July 5, 2016Publication date: January 24, 2019Inventors: Philippe Desbois, Rene Arbter, Bernd Bruchmann, Robert Stein, Frank Thielbeer, Rolf Muelhaupt, Tina Andrae
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Publication number: 20190023844Abstract: The invention provides a non-particulate cross-linked poly-?-lysine polymer. The poly-?-lysine and cross linker are linked by amide bonds and may the cross linker has at least two functional groups capable of reacting with an alpha carbon amine of poly-?-lysine. The polymer is suitably insoluble in water and other solvents and is provided in macro form for example a sheet, article or fibre. The macro form polymer is useful in a wide range of applications including wound treatment, as a medical diagnostic comprising a particulate support and a functional material bound or retained by the support and solid phase synthesis of peptides, oligonucleotides, oligosaccharides, immobilisation of species, cell culturing and in chromatographic separation.Type: ApplicationFiled: March 15, 2018Publication date: January 24, 2019Inventor: Donald A. Wellings
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Publication number: 20190023845Abstract: A method of making a polyetherimide comprising: reacting an aromatic bis(ether anhydride) with an aromatic diamine in a solvent to form a first solid/liquid mixture having a first solids content within 5% of a first target solids content; cooling the first solid/liquid mixture to a temperature within 5% of a target temperature; separating a portion of the liquid component from the cooled first solid/liquid mixture to form a second solid/liquid mixture having a second solids content within 10% of a second target solids content; and melt polymerizing the second solid/liquid mixture to form the polyetherimide.Type: ApplicationFiled: December 29, 2016Publication date: January 24, 2019Inventors: THOMAS LINK GUGGENHEIM, KARTHIK VENKATARAMAN
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Publication number: 20190023846Abstract: The present invention provides a polyamide-imide film which maintains transparency and has highly enhanced mechanical properties and heat resistance. The polyamide-imide shows excellent transparency, heat resistance, mechanical strength and flexibility and thus can be used in various fields such as substrates for devices, cover substrates for displays, optical films, integrated circuit (IC) packages, adhesive films, multi-layer flexible printed circuits (FPC), tapes, touch panels and protective films for optical disks.Type: ApplicationFiled: May 16, 2017Publication date: January 24, 2019Applicant: LG CHEM, LTD.Inventors: Cheolmin YUN, Jun Sik SUH, Kyungjun KIM
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Publication number: 20190023847Abstract: This invention is a composition capable of forming a heat-dissipating member that has high heat resistance and high thermal conductivity. This composition for a heat-dissipating member comprises a thermally conductive first inorganic filler bonded to one end of a first coupling agent, and a thermally conductive second inorganic filler bonded to one end of a second coupling agent, the composition being characterized in that: the other end of the first coupling agent and the other end of the second coupling agent are each bonded to a bifunctional or higher silsesquioxane by a curing treatment, as illustrated in FIG. 2; or at least one of the first coupling agent and the second coupling agent includes, in the structure thereof, a silsesquioxane, and the other end of the first coupling agent and the other end of the second coupling agent are bonded together as illustrated in FIG. 3.Type: ApplicationFiled: February 28, 2017Publication date: January 24, 2019Applicants: JNC CORPORATION, OSAKA RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takeshi FUJIWARA, TAKAYUKI HATTORI, JYUNICHI INAGAKI, TAKAFUMI KUNINOBU, Kazuhiro TAKIZAWA, YASUYUKI AGARI, HIROSHI HIRANO, JOJI KADOTA, AKINORI OKADA
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Publication number: 20190023848Abstract: A process of producing a silicone polymer includes hydrolyzing/condensating one or more compound in the presence of a base, thereby producing a silicone polymer that has an organic acid content of 0.0001 to 0.03 parts by weight with respect to 100 parts by weight of the silicone polymer. The process for producing a silicone polymer makes it possible to inhibit an increase in the molecular weight of a silicone polymer during high-temperature concentration in the steps of producing a silicone polymer.Type: ApplicationFiled: December 7, 2016Publication date: January 24, 2019Applicant: Toray Fine Chemicals Co., Ltd.Inventors: Masayuki Mizuta, Hiroyasu Seki, Hisatake Kobayashi, Hidetoshi Kato
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Publication number: 20190023849Abstract: The present invention pertains to an aerogel having a thermal conductivity of 0.03 W/m·K or less and a compressive elasticity modulus of 2 MPa or less at 25° C. under atmospheric pressure.Type: ApplicationFiled: September 25, 2018Publication date: January 24, 2019Inventors: Tomohiko KOTAKE, Masato MIYATAKE, Hikari MURAI
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Publication number: 20190023850Abstract: An organopolysiloxane emulsion composition which contains a polyoxyalkylene-modified organopolysiloxane compound represented by formula (1) as an emulsifying agent or as an emulsifying assistant. (LR2SiO1/2)a(R3SiO1/2)b(R2SiO2/2)c(RSiO3/2)d(SiO4/2)e ??(1) (In the formula, L represents a polyoxyalkylene group represented by formula (2); R represents a hydrogen atom, a hydroxy group, an alkyl group, an aryl group, an aralkyl group or an alkoxy group; a represents a number of 2-4; b represents a number of 0-2; c represents a number of 50-1,000; and each of d and e represents 0 or 1.) —H2C—CH2—(CH2)r—O-(EO)s-(AO)t—R1 ??(2) (In formula (2), EO represents an oxyethylene group; AO represents a linear or branched oxyalkylene group having 3-10 carbon atoms; R1 represents an alkyl group, a hydrogen atom, a carboxy group, an acyl group or a phenyl group; r represents a number of 0-10; s represents a number of 1-100, t represents a number of 0-150; and (s+t) represents a number of 15 or more.Type: ApplicationFiled: January 6, 2017Publication date: January 24, 2019Applicant: SHIN-ETSU CHEMICAL CO., LTD.Inventors: Yuko TAKADA, Shunji AOKI
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Publication number: 20190023851Abstract: The present invention provides a fluorine-containing, silicon-containing compound of formula (I): T1-(A-B)n-T2 which is useful as an additive.Type: ApplicationFiled: January 20, 2017Publication date: January 24, 2019Applicants: OCHANOMIZU UNIVERSITY, DAIKIN INDUSTRIES, LTD.Inventors: Tomoko YAJIMA, Kana SASAHARA, Tadashi KANBARA, Tsuyoshi NOGUCHI
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Publication number: 20190023852Abstract: Branched polyesters carrying dendrons are a useful class of nanomaterials which exhibit good handling properties and stability, can degrade to a high extent, and are effective encapsulation materials. They can be used to make nanoprecipitated particles which may for example be used in therapy. Furthermore, these materials can be synthesised by economical and tailorable processes. The materials can be prepared by the ring-opening polymerisation (ROP) of mono-functional lactone monomers and difunctional lactone monomers, using dendron initiators.Type: ApplicationFiled: December 29, 2016Publication date: January 24, 2019Inventors: Steven Rannard, Andrew Owen, Pierre Chambon, Hannah Rogers, Sarah Blackmore
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Publication number: 20190023853Abstract: The present invention relates to composition and an article prepared by applying the composition to paper. The composition comprises an aqueous dispersion of acrylic or styrene acrylic polymer particles having a hard phase and a soft phase, wherein both phases comprise structural units of an specific acid monomer. The composition further includes sub-stoichiometric levels of a Zn++ or Zr++++ with respect to the carboxylic acid groups. The composition is useful as imparting block and tack resistance as a coating on paper.Type: ApplicationFiled: July 17, 2018Publication date: January 24, 2019Inventors: Bryan L. McCulloch, John A. Roper, III, Kaitlin Rosen
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Publication number: 20190023854Abstract: A method for producing a polymer latex, including an emulsification step of emulsifying a polymer solution obtained by dissolution of synthetic polyisoprene and/or a styrene-isoprene-styrene block copolymer having a molecular weight distribution of 1.0 to 2.6 in an organic solvent, in water in the presence of a surfactant, to thereby obtain an emulsified liquid, wherein as the synthetic polyisoprene and/or styrene-isoprene-styrene block copolymer, used are/is synthetic polyisoprene and/or a styrene-isoprene-styrene block copolymer which, when dissolved in an organic solvent to thereby be formed into a polymer solution having a viscosity at a temperature of 60° C. of 20,000 cps, have/has a solid content concentration in the range of 10 to 60% by weight.Type: ApplicationFiled: January 26, 2017Publication date: January 24, 2019Applicant: ZEON CORPORATIONInventors: Hidetake ISHII, Junji KODEMURA
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Publication number: 20190023855Abstract: A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, said method including: i) providing a glycosaminoglycan crosslinked by amide bonds, wherein the crosslinked glycosaminoglycans include ester crosslinks formed as byproducts during the amide crosslinking; and ii) subjecting the crosslinked glycosaminoglycans to alkaline treatment to hydrolyze ester crosslinks formed as byproducts during the amide crosslinking.Type: ApplicationFiled: December 28, 2016Publication date: January 24, 2019Applicant: GALDERMA S.A.Inventors: Johan OLSSON, Hotan MOJARRADI