Patents Issued in February 7, 2019
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Publication number: 20190038809Abstract: The invention relates to the technical filed of tissue engineering and 3D printing, particularly relates to an artificial tissue progenitor and a method for preparing the same.Type: ApplicationFiled: August 27, 2018Publication date: February 7, 2019Inventors: Yujian James KANG, Xiao ZUO, Mingchun DU
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Publication number: 20190038810Abstract: Improved randomized porous structures and methods of manufacturing such porous structures are disclosed. The scaffold of the porous structures are formed from by dividing the space between a plurality of spatial coordinates of a defined volume, where the plurality of spatial coordinates have been moved in a random direction and a random finite distance according to a predetermined randomization limit.Type: ApplicationFiled: October 5, 2018Publication date: February 7, 2019Inventors: Ryan L. Landon, Aashiish Agnihotri, Laura J. Gilmour, Jeffrey Sharp, Randy C. Winebarger
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Publication number: 20190038811Abstract: Provided is a tympanic membrane or ear canal regeneration agent comprising a combination of a gelatin sponge that carries basic fibroblast growth factor (bFGF) and a covering material. The covering material is used not only to fix the gelatin sponge to the affected portion, but also for the purpose of preventing drying and infections to provide a culturing environment that is favorable for regenerating tissue isolated from the outside. To promote tissue regeneration, the margin of the tympanic membrane or ear canal defect is preferably freshened in advance.Type: ApplicationFiled: October 12, 2018Publication date: February 7, 2019Applicant: NOBELPHARMA CO., LTD.Inventor: Shin-ichi Kanemaru
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Publication number: 20190038812Abstract: A soft tissue filler comprising a biodegradable amino-acid derived polycarbonate-urethanes and methods of repairing soft tissue defects are provided. The biodegradable soft tissue filler comprises a porous scaffold that is the reaction product of: a) a divinyl oligomer component that comprises a carbonate-derived divinyl oligomer that is the reaction product of a lysine-derived diisocyanate, a vinyl coupling agent, and a polycarbonate and, optionally, an ether-derived divinyl oligomer, wherein the ether-derived divinyl oligomer is the reaction product of a lysine-derived diisocyanate, a vinyl coupling agent, and an ether; b) at least one anionic monomer; and c) at least one hydrophobic monomer. The molar ratio of (a):(b+c) is between about 1:?21 and about 1:30, the soft tissue filler has a porosity of >75%; and a compressive moduli of between about 1 kPa and about 50 kPa.Type: ApplicationFiled: February 16, 2017Publication date: February 7, 2019Inventors: Paul SANTERRE, Soror SHARIFPOOR, Wey Liang LEONG
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Publication number: 20190038813Abstract: The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been inserted in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising: (A) at least one taurinamide derivative, (B) at least one compound selected from the group consisting of biologically acceptable acids and biologically acceptable salts thereof; and (C) heparin at a low concentration.Type: ApplicationFiled: March 5, 2018Publication date: February 7, 2019Inventor: Frank R. Prosl
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Publication number: 20190038814Abstract: A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.Type: ApplicationFiled: October 8, 2018Publication date: February 7, 2019Inventor: James A. Walls
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Publication number: 20190038815Abstract: An implantable biocompatible material includes one or more vacuum deposited layers of biocompatible materials deposited upon a biocompatible base material. At least a top most vacuum deposited layer includes a homogeneous molecular pattern of distribution along the surface thereof and comprises a patterned array of geometric physiologically functional features.Type: ApplicationFiled: July 31, 2018Publication date: February 7, 2019Inventor: Julio C. Palmaz
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Publication number: 20190038816Abstract: Surgical tools are provided herein that are configured to apply suction and irrigation at a surgical site during the course of a surgical procedure. A surgical tool can include a handle that has a suction flow path configured to provide suction therethrough and an irrigation flow path configured to provide irrigation therethrough. The suction flow path and the irrigation flow path can share a common path along at least partial lengths thereof. An elongate shaft can extend distally from the handle and can have an inner lumen that is in communication with the suction flow path and the irrigation flow path. The inner lumen can thus be configured to provide suction from the suction flow path to a surgical site to remove matter therefrom and to provide irrigation from the irrigation flow path to the surgical site to provide fluid thereto.Type: ApplicationFiled: August 1, 2017Publication date: February 7, 2019Inventors: Rudolph H. Nobis, Patrick J. Minnelli, Kevin M. Montgomery
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Publication number: 20190038817Abstract: Described herein are devices and methods for irrigating and suctioning fluids from the lumens or cavities of a mammalian body. The devices include a malleable irrigation tube and a suction tube that is slidably mounted upon the irrigation tube.Type: ApplicationFiled: April 28, 2016Publication date: February 7, 2019Applicant: ENTELLUS MEDICAL, INC.Inventors: Andrew T. Forsberg, John R. Drontle, Anthony J. Hanson
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Publication number: 20190038818Abstract: A breast pump includes a container, a host unit disposed above and communicating with the container, an electric heating cup disposed at a front end of the host unit and communicating with the container, an electric heating element, and a heat insulation. The electric heating cup includes an inner cover and an outer cover. The electric heating element and the heat insulation are disposed between the inner cover and the outer cover. The heat insulation is disposed between the electric heating element and the outer cover. Positive and negative electrodes of the electric heating element are connected to conducting plates disposed in the inner side of the outer cover via connection wires. The conducting plates extend to the outer side of the outer cover and are in electric connection to contact chips disposed at the lower front end of the host unit.Type: ApplicationFiled: October 7, 2018Publication date: February 7, 2019Inventor: Min HU
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Publication number: 20190038819Abstract: A system is provided for connecting a blood pump to a heart, the system comprising: a blood pump for conveying blood, wherein the blood pump comprises a first tubular portion and a second tubular portion, and between the first and the second tubular portion, there is a flange-shaped portion; and comprising a connector having a tubular connector portion extending in an axial direction between a distal end and a proximal end having a lumen for receiving the first tubular portion of the blood pump, and having a flange-shaped connector portion arranged at the distal end for fastening the connector to an organ.Type: ApplicationFiled: September 12, 2016Publication date: February 7, 2019Applicant: Berlin Heart GmbHInventors: Nedim Arslan, Heiko Gundlach, Benjamin Daniel Kaebe, Gerhard Lauterbach, Michael Matthes, Kim Peter Winterwerber
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Publication number: 20190038820Abstract: A blood pump may be provided that includes an inlet, an outlet and a rotor for delivering fluid from the inlet to the outlet, wherein the rotor is suspended within the blood pump by radial passive magnetic forces and axially is preloaded in one direction at least by way of passive magnetic forces so that, during a fluid-delivering rotation of the rotor, the axial thrust of the rotor acts counter to the magnetic attraction acting axially in the direction of the outlet.Type: ApplicationFiled: February 6, 2017Publication date: February 7, 2019Applicant: Berlin Heart GmbHInventors: Marcus Granegger, Kim Peter Winterwerber, Hendryk Richert, Bodo Schmidt, Oliver Peters
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Publication number: 20190038821Abstract: A blood pump housing device designed to enclose and protect a total artificial heart when implanted in a subject is disclosed. The blood pump housing device comprises a first and second artificial heart pump receiving part (3a, 3b) configured to receive and partly enclose a first and a second artificial heart pump (20a, 20b) of a total artificial heart (TAH); and a first and second pump actuation enclosing part (4a, 4b) configured to partly enclose a first and second pump actuation means (60a, 60b), said artificial heart pump receiving parts (3a, 3b) and pump actuation means enclosing parts (4a, 4b) are arranged to connect to each other in a leak-free manner.Type: ApplicationFiled: February 9, 2017Publication date: February 7, 2019Inventor: Azad Najar
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Publication number: 20190038822Abstract: An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.Type: ApplicationFiled: October 12, 2018Publication date: February 7, 2019Applicant: MAQUET Cardiovascular LLCInventors: Walid N. ABOUL-HOSN, William R. KANZ, Bruce A. BAKER
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Publication number: 20190038823Abstract: The invention relates to an apparatus for extracorporeal blood treatment that comprises a device 1 for providing fresh dialysate and a drain 2 for used dialysate, a balancing device 4 for balancing fresh dialysate and used dialysate, an ultrafiltration device 15, and a dialyser 3 that is divided into a blood chamber 6 and a dialysate chamber 7 by a semi-permeable membrane 5. The invention further relates to a method for operating such an apparatus for extracorporeal blood treatment. The apparatus according to the invention is based on the use of the ultrafiltration device 15 of the blood treatment apparatus for raising the liquid level in the air separation device 12 on the secondary side of the dialysate system I. In the apparatus according to the invention, the ultrafiltration device 15 is designed such that the ultrafiltration device can be operated not only in an ultrafiltration mode, but also in a ventilation mode.Type: ApplicationFiled: January 4, 2017Publication date: February 7, 2019Inventor: Jurgen HACKER
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Publication number: 20190038824Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.Type: ApplicationFiled: October 9, 2018Publication date: February 7, 2019Inventors: Bryant J. Pudil, Thomas E. Meyer, David B. Lura, Martin T. Gerber
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Publication number: 20190038825Abstract: Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage deairing of blood to provide automated cardiopulmonary replacement to sustain patient life during a medical procedure such as; cardiopulmonary bypass graft surgery, keyhole cardiopulmonary bypass graft surgery, percutaneous angioplasty, percutaneous stent placement, and percutaneous atherectomy, repairing or replacing the heart valve and/or for perfusing an organ or the body of an organ donor to preserve viability of organ(s) for transplantation.Type: ApplicationFiled: November 6, 2017Publication date: February 7, 2019Inventors: Gerhard Muller-Spanka, Hans Reinhard Zerkowski
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Publication number: 20190038826Abstract: A blood filtration method, system, device and media for removing gram negative bacteria from the blood wherein the media includes a substrate coated with mannose optionally in constitution with substrate coated with heparin.Type: ApplicationFiled: August 2, 2018Publication date: February 7, 2019Applicant: ExThera Medical CorporationInventors: KEITH MCCREA, ROBERT WARD, OLLE LARM, LARS ADOLFSSON
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Publication number: 20190038827Abstract: An extracorporeal heart-lung support machine apparatus includes a platform capable of supporting one or more pieces of equipment and at least one coupler mounted to the platform so as to provide a docking interface for a piece of equipment, wherein the coupler includes: an electrical interface configured to matingly engage wills a complementary configured electrical interface of the at least one piece of equipment; and a locking mechanism configured to selectively transition between a locked configuration in which a latch member of the locking mechanism is positioned to secure fee at least one piece of equipment to the coupler and m unlocked configuration in which the latch member of the locking mechanism is positioned to permit both engagement or disengagement of the electrical interface of the coupler with the electrical interface of the at least one piece of equipment.Type: ApplicationFiled: May 12, 2016Publication date: February 7, 2019Applicant: Maquet Cardiopulmonary GmbHInventors: Robert HOFF, Daniel A. WALTERS
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Publication number: 20190038828Abstract: A system for sterilizing a drug delivery device includes a drug delivery device having a first self-healing seal configured to seal a fluid reservoir disposed within the drug delivery device. A sealable container is configured to receive the drug delivery device therein. The sealable container has a base portion and a cover portion. The cover portion has a second self-healing seal positioned to align with the first self-healing seal when the drug delivery device is disposed within the sealable container. A fill port includes a fill path, the fill path being configured to pass through the first and second self-healing seals to fluidly couple the fill port to the reservoir of the drug delivery device. Other systems, methods, and devices of sterilization are also disclosed.Type: ApplicationFiled: August 2, 2018Publication date: February 7, 2019Inventor: Ian MCLAUGHLIN
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Publication number: 20190038829Abstract: What is disclosed is an organizational rack for organizing and storing syringes. The organizational rack is particularly useful in storing syringes that are utilized for dispensing an oral medication. This rack includes a base from which a series of projections emanate. This includes a base projection into which a cap of a syringe for oral dispensing of medicine is placed. The device utilizes a second projection that incorporates openings or notches into which the barrel of the syringe fits. The rack has a third projection that utilizes an opening. The space between the third projection and the first projection is configured such that when a syringe cap is placed in an opening in the first projection, the barrel of the syringe fits between the first projection and the third projection such that friction is placed on the finger grips of the syringe to hold the syringe in place.Type: ApplicationFiled: August 1, 2018Publication date: February 7, 2019Inventor: BLANCA NASKER
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Publication number: 20190038830Abstract: A patient care system is configured for infusing fluid to a patient. The system includes a plurality of modular fluid infusion pumps that each has a connector for connecting to a modular programming unit or to one another. Systems and methods are configured for verifying that the connectors are reliably performing their functions or communicatively connecting the pumps to one another or to the programming unit.Type: ApplicationFiled: August 6, 2018Publication date: February 7, 2019Inventor: Andre Gamelin
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Publication number: 20190038831Abstract: Methods and related systems for modulating neural activity by modulating neural activity in a nerve plexus of a subject are disclosed. Neural activity may be modulated by stimuli delivered via various types of stimulus sources. Neural modulation may be used, for example, to modulate an undesired sensation, such as pain. Delivery of stimuli for modulating neural activity may be controlled in part in based on an activity state of the subject.Type: ApplicationFiled: October 8, 2018Publication date: February 7, 2019Inventors: Ralph G. Dacey, JR., Gregory J. Della Rocca, Colin P. Derdeyn, Joshua L. Dowling, Eleanor V. Goodall, Roderick A. Hyde, Muriel Y. Ishikawa, Jordin T. Kare, Eric C. Leuthardt, Nathan P. Myhrvold, Michael A. Smith, Lowell L. Wood, JR., Victoria Y.H. Wood, Gregory J. Zipfel
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Publication number: 20190038832Abstract: An indwelling assembly includes an inner needle having a sharp needlepoint, an inner needle hub fixed to the inner needle, a hollow elongated outer member in which the inner needle is positioned and movable in a distal direction relative to the inner needle after puncturing the blood vessel to position the elongated outer member at a desired position in the blood vessel, an outer member hub fixed to hollow elongated outer member, a projection removably connected to the outer member hub and configured to be engaged by a finger of the user to apply a force to the projection causing the outer member hub and the hollow elongated outer member to move together with the projection in the distal direction relative to the inner needle and the inner needle hub, and an elongated movable member that is movable relative to the hollow elongated outer member and the outer member hub.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: Terumo Kabushiki KaishaInventor: Masahiro Ishida
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Publication number: 20190038833Abstract: A solution infusion apparatus (1), particularly for dialysis systems, comprising at least one main pouch (3, 3?) adapted to contain a solution and comprising a pump (5) configured for introducing the solution in the blood circuit of a dialysis system. The apparatus further comprises at least one additional pouch (7) that is hydraulically connected to the at least one main pouch (3, 3?), wherein the pump (5) is configured to draw the solution from the at least one additional pouch (7).Type: ApplicationFiled: January 27, 2017Publication date: February 7, 2019Inventors: Paolo PIRAZZOLI, Renato PEDRAZZI
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Publication number: 20190038834Abstract: The systems, methods and articles described herein are directed to at least one pressure sensor along a downstream fluid line which senses fluid pressure and assists an occlusion detection feature in determining the presence of occlusions in the downstream fluid line. In addition, the system can dynamically adapt the occlusion detection feature based on a delivery of fluid, such as a bolus, in order to prevent the system from creating a false alarm regarding an occlusion of the downstream fluid line.Type: ApplicationFiled: July 16, 2018Publication date: February 7, 2019Inventors: Donald Halbert, Jesse Guerra, Stephen Bollish
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Publication number: 20190038835Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.Type: ApplicationFiled: July 30, 2018Publication date: February 7, 2019Inventors: David NAZZARO, Ian MCLAUGHLIN, Daniel ALLIS, Jason O'CONNOR
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Publication number: 20190038836Abstract: A multi chamber syringe unit (1) comprises a body (2), a separating element (3) and a bypass arrangement (26). The body (2) has a distal end side (23), a proximal end side (22) opposite to the distal end side (23), an interior limited by a side wall (21) between the distal end side (23) and the proximal end side (22) and a longitudinal axis (27) centrally extending from the distal end side (23) to the proximal end side (22) through the body. The separating element (3) is arranged in the interior of the body (2) forming a distal chamber (24) between the distal end side (23) and the separating element (3) and a proximal chamber (25) between the proximal end side (22) and the separating element (3). The bypass arrangement (26; 260; 268; 269) is a section of the body (2) in which the interior has a constant noncircular cross section (261) orthogonal to the longitudinal axis (27).Type: ApplicationFiled: February 3, 2017Publication date: February 7, 2019Inventors: Jörg LÜMKEMANN, Tobias WERK
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Publication number: 20190038837Abstract: An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor.Type: ApplicationFiled: July 10, 2018Publication date: February 7, 2019Inventors: Kevin Bokelman, George M. Wohlhieter, Thomas F. McGee, Arthur G. Marlin, Stefanie A. Hurowitz, David R. Jansen, Ellen Ni Chathail
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Publication number: 20190038838Abstract: A manual subcutaneous jet injector includes an injector body having an injection portion provided with an injection system including an injection fluid volume fluidically connected to a subcutaneous injector outlet, and a pumping portion. The pumping portion includes an interior chamber having a pumping portion and a pressure chamber portion fluidically connected to the injection fluid volume. A manually operated injector pump is arranged in the pumping portion. At least one one-way valve is arranged between the pumping portion and the pressure chamber portion, the one-way valve including an inlet end and an outlet end. A piston is arranged in the pumping portion at the inlet end of the one-way valve.Type: ApplicationFiled: August 1, 2017Publication date: February 7, 2019Inventors: Andrew C. Hicks, Alex M. Hytha
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Publication number: 20190038839Abstract: A method of manually charging a subcutaneous jet injector includes shifting a piston arranged within a pressure chamber portion of the subcutaneous jet injector, forcing a fluid through a one-way valve with the piston into a chamber of the subcutaneous jet injector, pressurizing the fluid in the chamber creating a pressurized fluid, forcing the pressurized fluid in the chamber into another chamber including a bolus dose of injectable fluid, and directing the bolus dose of injectable fluid from the subcutaneous jet injector with the pressurized fluid.Type: ApplicationFiled: November 7, 2017Publication date: February 7, 2019Inventors: Andrew C. Hicks, Alex M. Hytha
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Publication number: 20190038840Abstract: A sensor for detecting a change in state of an asset comprising including a transmission antenna operable to transmit a control signal to an external device, control electronics connected to the transmission antenna configured to provide instructions to the transmission antenna to transmit the control signal, and a bypass antenna positioned and configured to prevent the control electronics from providing the instructions to the transmission antenna when the bypass antenna is in an undisturbed position and to permit the control electronics to provide the instructions to the transmission antenna when the bypass antenna is displaced from the undisturbed position.Type: ApplicationFiled: July 3, 2018Publication date: February 7, 2019Inventor: Minhong Yu
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Publication number: 20190038841Abstract: A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.Type: ApplicationFiled: October 5, 2018Publication date: February 7, 2019Inventor: Mads Schenstroem Stefansen
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Publication number: 20190038842Abstract: The invention relates to a torsion spring driven injection device for delivering individually set doses of a liquid drug wherein a torsion spring is strained by rotation of a rotatable dose setting element and released by axial movement of a clutch which couples the dose setting element with the drive tube and the drive tube with a piston rod guide driving the piston rod. When straining the torsion spring the clutch is decoupled from a piston rod guide such that the piston rod guide is able to rotate independently and coupled to the dose setting element. During dose expelling the clutch is moved into engagement with the piston rod guide and out of engagement with the dose setting element such that the piston rod guide rotates with the clutch under influence of the torsion spring. The invention further relates to a non-axial movable End-of-Content mechanism preventing the user from setting a dose larger than the content of the injectable liquid drug remaining in the cartridge of the injection device.Type: ApplicationFiled: February 2, 2017Publication date: February 7, 2019Inventors: Simon Munch Pedersen, Simon Roervig
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Publication number: 20190038843Abstract: A reusable medication delivery device that can determine medication remaining in a simple fashion. The device includes a first sensor (200) for sensing when a cartridge is mounted in the device, and at least one second sensor for sensing a retraction of a drive member (160) that engages a cartridge plunger (132). The device includes a controller that determines, based on inputs from the first sensor and the at least one second sensor, that a newly installed cartridge is to be considered full or not full of medication. The controller calculates, after a medication delivery and based on an input from a means for determining an amount of medication delivered by operation of a dose delivery mechanism, and if the cartridge was considered full when newly installed, a quantity of medication remaining in the installed cartridge after the medication delivery.Type: ApplicationFiled: February 21, 2017Publication date: February 7, 2019Inventors: Roy H. Byerly, Russell W. Perkins, Giorgio M. Sardo
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Publication number: 20190038844Abstract: The invention relates to an injection device for injecting dosed amounts of a liquid therapeutic agent, comprising a receiving system for the therapeutic agent, an application system for transferring the therapeutic agent to an application site, a dosing system for transferring the therapeutic agent from the receiving system to the application system, a trigger system for activating the dosing system, and a detection system for detecting the amount of the therapeutic agent applied. According to the invention, a sensor arrangement comprises at least one recognition system which detects, prior to injection, whether the therapeutic agent has been mixed.Type: ApplicationFiled: February 8, 2017Publication date: February 7, 2019Inventors: Janko SCHILDT, Markus BENTRUP
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Publication number: 20190038845Abstract: The invention relates to an activator unit for an autoinjector, comprising a substantially cylindrical housing (3) in which an axially movable pressure pin (4) is guided, said pressure pin being insertable counter to a spring unit and being lockable, when inserted, by means of detent projections (6) of a retaining element (5) that is connected to the pressure pin. The spring unit comprises a first coil spring (1) and at least one second coil spring (2) having a larger diameter than the first coil spring, the second coil spring being coaxial to the first coil spring.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: PHARMA CONSULT GES.M.B.HInventors: Andreas SCHWIRTZ, Markus CSENAR
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Publication number: 20190038846Abstract: A port-a-cath needle adapted for determining the position of the needle prior to dispensing medical treatments is disclosed. Disclosed embodiments of the port-a-cath needle comprises a cannula, a hollow needle, and an inflatable balloon. The balloon is disposed at the distal end of the port-a-cath needle such that when the needle is inserted into a patient, the balloon may be inflated and the resistance pressure used to determine if the needle is inserted into the port chamber or a port-a-cath device or is surrounded by soft tissue. In certain embodiments, the balloon may be maintained in the inflated configuration in order to help retain the port-a-cath needle within the port chamber while treatment is delivered to the patient.Type: ApplicationFiled: August 1, 2017Publication date: February 7, 2019Inventor: Tejash Patel
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Publication number: 20190038847Abstract: The invention relates to a Safe Syringe comprising a barrel, a needle seat and a plunger, wherein the needle seat has a hook rod, a linkage deformation portion and a barrel clamping portion; and the plunger has a rod body, and a hook insertion hole which can be sleeved with the hook rod of the needle seat and compress the linkage deformation portion for elastic deformation such that the barrel clamping portion of the needle seat is not clamped into the seat clamping slot of the barrel, and the hook insertion hole can hook the hook rod of the needle seat to move the needle seat. The Safe Syringe can allow stable positioning and quick pullback of the needle seat and effectively reduce liquid medicine residue.Type: ApplicationFiled: December 26, 2016Publication date: February 7, 2019Inventor: WEN-CHIN LU
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Publication number: 20190038848Abstract: An autoinjector includes a case adapted to hold a medicament container, a needle shroud telescopically coupled to the case, and a plunger slidably disposed in the case. The needle shroud is movable between a first extended position, a retracted position, and a second extended position relative to the case. The plunger is movable between a proximal position, an intermediate position, and a distal position relative to the case. When the plunger is in the intermediate position and the needle shroud is in the retracted position, the plunger abuts the case to prevent the needle shroud from returning to the extended position. When the plunger is in the distal position and the needle shroud is in the second extended position, the plunger abuts the case to prevent the needle shroud from returning to the retracted position.Type: ApplicationFiled: October 11, 2018Publication date: February 7, 2019Inventors: Stefan Taal, Thomas Kemp
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Publication number: 20190038849Abstract: Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.Type: ApplicationFiled: October 12, 2018Publication date: February 7, 2019Inventors: James J. Yoo, Anthony Atala, Kyle W. Binder, Mohammad Z. Albanna, Weixin Zhao, Dennis Dice, Tao Xu
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Publication number: 20190038850Abstract: The invention relates to a nozzle for use in a device for administering a liquid medical formulation, to a method for producing the nozzle in the form of a microfluidic component and to a tool for producing microstructures of the microfluidic component. The nozzle is formed by a plastics plate with groove-like microstructures which are covered by a plastics cover on the longitudinal side in a fixed manner. The production method includes a moulding process in which a moulding tool is used, which moulding tool has complementary metal microstructures which have been produced from a semiconductor material in an electrodeposition process by means of a master component.Type: ApplicationFiled: February 2, 2017Publication date: February 7, 2019Inventors: Klaus KADEL, Lothar KEYDEL
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Publication number: 20190038851Abstract: Nebulizers are used to deliver a medicine to a patient's lungs in the form of an airstream, with fluid comprising the medicine entrained in the airstream. To enable the fluid to be entrained in the airstream, a nebulizer contains an aerosol generator typically comprising a vibratory element (28) with a piezoelectric actuator. There is a need to frequently sterilize the nebulizer. This involves dipping the nebulizer in boiling water for a significant time. It has been found that repeated sterilization cycles can force water through gaps in the vibratory element, and its encapsulation (26), and damage the piezo element. The present invention proposes to more effectively seal the piezo of the vibratory element (28) from the effects of water ingress. In particular, it is proposed to create, at an interface of the vibratory element (28) and the encapsulating element (26), a discontinuity which provides a barrier geometry.Type: ApplicationFiled: January 25, 2017Publication date: February 7, 2019Applicant: KONINKLIJKE PHILIPS N.V.Inventor: MARKUS HIJLKEMA
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Publication number: 20190038852Abstract: A nebulizer is provided to atomize a liquid medication for rapid delivery of an aerosol spray to a user via inhalation. The nebulizer includes a jar having a compressed gas passage. A jet cooperates with the jar and has a jet orifice through which the liquid medication and the compressed gas are discharged to form an aerosol flow. The cap is connected to the jar to define an inner chamber. The cap includes an entrainment port for ambient room air, and a chimney in fluid communication with the entrainment port and the inner chamber. A deflector base having an impingement member is located adjacent to the entrainment chimney and is spaced below an opening thereof by a predetermined distance to provide a flow of the ambient room air to be entrained in the aerosol flow in order to enhance nebulization speed while maintaining a desired aerosol particle size.Type: ApplicationFiled: July 23, 2018Publication date: February 7, 2019Inventors: Daniel P. DWYER, Erin GRAHAM
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Publication number: 20190038853Abstract: Controlling device particularly adapted for administering a therapeutic composition, that includes (i) a power input element configured to connect with and receive power from a power source; (ii) a power adjustment device connected to said power input element optionally comprising a data input element connected to a data processing device; (iii) a power output element connected to said power adjustment device and configured to connect with and provide power to a processing element; optionally (iv) a data output element connected to the data processing device and connected to said power output element; wherein said power output element is configured to be controlled by said power adjustment device and wherein said controlling device is configured to be readily removable from the power source and the processing element.Type: ApplicationFiled: October 9, 2018Publication date: February 7, 2019Applicant: CANABOLABSInventors: Aharon M. EYAL, Shay Avraham SARID
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Publication number: 20190038854Abstract: The present invention relates to a medical evaluation device (10) for evaluating an adherence to a therapy protocol when using an aerosol nebulizer (30) having an aerosol generator (31) for nebulizing a liquid medication according to said therapy protocol, said medical evaluation device (10) comprising: a communication unit (100), configured to establish a communication connection with a communication device (20), said communication connection being configured for: providing first configuration data to a nebulizer control device (40) of said aerosol nebulizer (30) via said communication device (20), said first configuration data for configuring said aerosol nebulizer according to said therapy protocol; and receiving nebulizing data indicating an operation of said aerosol nebulizer from said communication device (20); further comprising an evaluation unit (110), configured to evaluate said adherence to said therapy protocol based on a comparison of said received nebulizing data with respective parameters definType: ApplicationFiled: February 8, 2017Publication date: February 7, 2019Applicant: PARI Pharma GmbHInventors: Carola Fuchs, Matthias Finke, Björn Eschrich, Ronald Schmidt
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Publication number: 20190038855Abstract: The present disclosure relates to a dose indicator for a pressure-actuated metered dose inhaler (pMDI) device.Type: ApplicationFiled: October 8, 2018Publication date: February 7, 2019Inventors: ADAM J. STUART, PETER D. HODSON
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Publication number: 20190038856Abstract: Since some of the Individual States of the Federal Government no longer prosecute individuals for the possession or sale of medical marijuana, as long as compliance within the states sale regulations are followed, a new industry has emerged, Medical Cannabis. Medical Cannabis is cannabis and cannabinoids that are prescribed by a medical doctor to their patents to alleviate certain types of nausea and vomiting associated with chemotherapy, also to improve appetite in HIV/AIDS patients and to reduce chronic pain and muscle spasms. This has produced many problems specifically dosage and dosage control. A cigarette from tip to filter contains about one mg nicotine and is controlled by the cigarette industry, as this is the typical amount to addict a person.Type: ApplicationFiled: August 7, 2017Publication date: February 7, 2019Inventor: Marvin Manuel Boone, JR.
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Publication number: 20190038857Abstract: A blower includes a housing including an inlet and an outlet, a motor to drive a rotatable shaft, first and second impellers provided to the shaft, the first and second impellers each including a plurality of impeller blades, a first stationary component provided to the housing and including stator vanes downstream of the first impeller, and a second stationary component provided to the housing and including stator vanes downstream of the second impeller. A first set of stator vanes of the first stationary component is provided around the motor and are configured and arranged to direct airflow along the motor, to de-swirl the airflow and to decelerate air to increase pressure. A blower including a third impeller and third stationary component positioned above the first impeller is also described.Type: ApplicationFiled: October 12, 2018Publication date: February 7, 2019Inventors: Barton John KENYON, Jeegarkumar KAPADIA, Melanie Lucia CARIOLA, Michael Bruce MOIR, Aleksandr S. NAGORNY, Christopher Scott EDWARDS, James McKensey BENCKE, Paul Andrew DICKENS
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Publication number: 20190038858Abstract: A continuous positive airway pressure (CPAP) apparatus for respiratory assistance of a patient is disclosed. There is a blower having an output connectible to a ventilation mask wearable by the patient. A first pressure sensor measures blower pressure at the output of the blower, and a second pressure sensor that is connectible to the ventilation mask measures mask pressure therein. A pressure controller is connected to the first pressure sensor and the second pressure sensor, and a patient inspiratory phase and a patient expiratory phase is be detectable by the pressure controller to regulate therapeutic airflow delivered to the patient based upon pressure differentials between the mask pressure and the blower pressure.Type: ApplicationFiled: October 8, 2018Publication date: February 7, 2019Inventors: Samir S. Ahmad, Leonardo Alberto Baloa Welzien, Enrico Brambilla