Abstract: A method for regulating immune cells includes applying a stimulus to a specific area to be stimulated at a body surface by a stimulus applying apparatus so as to bring an increase rate of a blood flow to 60% or more, preferably, 100% or more. The blood flow is measured by a laser Doppler tissue blood flow meter attached to a central part of an inner side of a wrist joint. The regulating and balancing these T cell groups finely is essential to maintain the immune system of human beings and increase in blood flow volume by thermal therapy enables a regulatory T cell to regulate and balance the immune cells.

Abstract: Apparatuses and methods to enhance sleep, reduce sleep onset latency, extend sleep duration and/or increasing the duration of deeper sleep stages relative to stage 1 sleep. In general, these apparatuses and methods apply and maintain one or more target “warm” temperatures to a subject's forehead for a time period. The target temperature may be between 25° C. and 42° C. The target temperature may be a fixed amount greater than ambient temperature. The time period may be a fixed time period or a variable time period. These methods and apparatuses may limit the application of thermal energy to the subject's forehead region.

Abstract: Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.

Abstract: An eye drop assist apparatus and method for sequentially administering an ocular medication into a patient's eyes. A bottle or vial containing liquid eye drops is supported in a holder. First and second nasal locators extend in opposite directions from the holder. The nasal locators are separated by the pupillary distance (typically 60 mm), with the dispensing tip of the bottle located mid-way between. A person administering eye drops abuts the first nasal locator against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a first eye before squeezing the bottle to forcibly expel one or more drops into the first eye. The person then linearly translates the bottle so that the second nasal locator abuts against the top of the patient's nasal bridge while aligning the tip of the bottle directly over a second eye. The bottle is then squeezed again to forcibly expel drops into the second eye.

Abstract: Vitrectomy probe (1) for the removal of the vitreous humour (1a) and comprising a tube (2) adapted to be put into direct contact with the vitreous (1a), defining a main axis (2a) and including an internal passage (21) and a opening (23) enabling the vitreous (1a) to enter the internal passage (21) and comprising at least one cutting edge (23a, 23b); a suction system suitable for the creation of vacuum within the internal passage (21) sucking the vitreous (1a) into the opening (23); a drive unit adapted to move the tube (2) defining a vibrational motion (A) of the tube (2) which therefore produces pressure waves reducing the viscosity of the vitreous (1a), and a reciprocating motion (B), having a frequency lower than the frequency of the vibrational motion (A), adapted to enable the cutting edges (23a, 23b) to cut the vitreous (1a)

Abstract: A Device for producing cuts or perforations on a human or animal eye at the anterior or posterior opening of the eye lens (capsulatomy, rhexis) with a cutting element that can be inserted into the interior of the eye and a drive device which is arranged outside of the eye in order to cause movement, in particular oscillatory vibrations or rotation of the cutting element inside the interior of the eye, the drive device having a field generator for generating a magnetic or electromagnetic excitation field and the cutting element can be excited, in particular driven, by way of the excitation field generated by the field generator.

Abstract: The invention relates to a method for forming curved cuts in a transparent material, in particular in the cornea, by the creation of optical perforations in said material using laser radiation that is focused in the material. The focal point is displaced three-dimensionally to form the cut by lining up the optical perforations. The focal point is displaced in a first spatial direction by a displaceable lens and said focal directions in such a way that it follows the contours of the cut, which lie on a plane that is substantially perpendicular to the first spatial direction.

Abstract: Systems and methods for increasing the amplitude of accommodation of an eye, changing the refractive power of lens material of a natural crystalline lens of the eye, and addressing presbyopia are is provided. Generally, there are provided methods and systems for delivering a laser beam to a lens of an eye in a plurality of laser shots, which are in precise and predetermined patterns results in the weakening of the lens material.

Abstract: A laser probe with a replaceable optic fiber may include a reusable handle, a reusable housing tube, a reusable handle adapter, a reusable machine adapter, and a replaceable optic fiber. The handle adapter may interface with a proximal end of the handle. The machine adapter may interface with a surgical machine. The replaceable optic fiber may include an optic fiber having a first optic fiber end and a second optic fiber end, a first connector, and a second connector. The optic fiber may be disposed within the first connector and the second connector. The first connector may be temporarily fixed within the handle adapter and the second connector may be temporarily fixed within the machine adapter.

Abstract: The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The invention relates to a multi-blade device for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

Abstract: A three-layered wound dressing, including: a first layer, a second layer, and a third layer. The first layer includes a blend of first hydrophilic fibers and first hydrophobic fibers, the second layer includes a blend of second hydrophilic fibers and second hydrophobic fibers, and the third layer includes hydrophobic fibers. The second layer is disposed between the first layer and the third layer. In use, the first layer contacts a wound.

Abstract: A medical dressing includes an adhesive, permeable layer, a fabric support, and a hydrochromatic layer. The adhesive, permeable layer is configured to adhere to skin near a wound, for example, an intravenous catheter or other percutaneous device insertion site. The fabric support is disposed on the adhesive, permeable layer. The hydrochromatic layer is disposed on the fabric support, and is configured to change a color appearance responsive to contact with moisture.

Abstract: The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Abstract: A unit for forming absorbent sanitary articles including a drum rotatable about its axis of rotation and having a circumferential peripheral surface movable along a feed direction, first feeding means for feeding a succession of pairs of panels of material facing the circumferential peripheral surface and configured to position each pair in such a way that the respective two panels are facing each other and transversely aligned with the feed direction and second feeding means for feeding a continuous web of material suitable for defining at least part of the main body of an absorbent sanitary article, and configured to position the web on the circumferential peripheral surface of the drum in such a way that each panel projects partly sideways from the web.

Abstract: An absorbent article (100-1200) is capable of providing comfort to the wearer and can maintain dryness and inhibit the leakage of fluid. The absorbent article (100-1200) includes a multi-layered topsheet (138). The multi-layered topsheet (138) includes a first topsheet layer (106) having an opening (148) and a second topsheet layer (108) disposed under the first topsheet layer (106). The first topsheet layer (106) and the second topsheet layer (108) are joined together by a seal that, in one embodiment, generally corresponds with the shape of the opening (148). Further, a first sub-topsheet layer (116) is situated beneath the multi-layered topsheet (138) and has an opening (150) that is smaller than the first topsheet layer opening (148). This combination of openings (148, 150) situated one below the other provides for an absorbent article (100-1200) that can maintain a high level of dryness and its ability to conform to the wearer's body, and inhibit the leakage of bodily fluids due to a funnel-like effect.

Abstract: An elastic structure for absorbent sanitary products, comprising a sleeve comprising a first layer and a second layer overlapping each other, at least one elastic thread, and a plurality of first connecting portions spaced apart in a longitudinal direction, wherein each of said first connecting portions comprises two first welds arranged on opposite sides of the thread, wherein the first welds weld said first and second layers to each other in a first longitudinal portion of said sleeve, and a plurality of second connecting portions spaced apart in the longitudinal direction, wherein each of said second connecting portions comprises at least one second weld, wherein said second welds weld said first and second layers to each other in a second longitudinal portion of said sleeve without axially connecting the thread to said second longitudinal portion of the sleeve.

Abstract: A patient incontinence and lifting pad is an apparatus utilized to absorb urine excreted by a bedridden patient as well as to facilitate turning and lifting the patient. The apparatus includes a bed pad on which the patient is able to lie as well as an attached first securing strap and a second securing strap used to anchor the bed pad to a hospital bed railing or similar structure. An elongated band of the first securing strap and the second securing strap may be attached to itself in order to anchor the bed pad. An absorbent incontinence pad insert for absorbing urine is inserted within a slot on the bed pad and may be removable/replaceable. The absorbent incontinence pad insert may be held in place within the slot by a peripheral hook fastener strip.

Abstract: Devices, kits and methods described herein may be for treatment to skin, including but not limited to wound healing, the treatment, amelioration, and/or prevention of scars or keloids. An applicator and/or tensioning device may be used to apply a dressing to a subject. The applicator and/or tensioning device applies and/or maintains a strain in an elastic dressing, wherein at least some of the strain is out-of-plane or at a non-orthogonal, non-parallel and non-aligned orientation to other strains in the dressing.

Abstract: A mobile screening apparatus has a patient compartment having a floor, and end wall, a first sidewall and a second sidewall. The second sidewall has an expanding wall that is movable between a retracted position and an extended position. The mobile screening apparatus also has a scanner positioned in the patient compartment. The scanner has a length dimension extending longitudinally within the patient compartment. A scanning table is positioned within the patient compartment. The scanning table is movable in relation to the scanner. The patient compartment is positioned upon a chassis of a vehicle. A generator is connected to the scanner so as to supply power to the scanner. In particular, the scanner is a lung scanner.

Abstract: Disclosed is a hand-held control (1) for furniture drives (81), comprising a touch-sensitive control panel section (3, 3a, 3b) that has a number of actuation surfaces (4). A method for detecting actuation of the hand-held control (1) is also provided. An electromotive furniture drive (81) is fitted with a hand-held control (1) of this type.

Abstract: A bed step stool for assisting a user into and out of bed including opposite sides, a head, and a foot. The bed step stool includes a first support to be disposed closer to the head of the bed; a second support to be disposed closer to the foot of the bed; and a step assembly supported between the first support and the second support, the step assembly to enable the user to step thereon for assisting the user into and out of the bed.

Abstract: An autonomous wheeled transportation device (1) for transporting beds and other items. The wheeled transportation device (1) comprises a base, with a lower part having a number of wheels (8, 12, 22). The autonomous wheeled transportation device (1) comprises at least one movable first engagement member (13) adapted to engage a frame part (14) of a bed, the movable first engagement member being movable between a resting engagement member position at or below a plane and horizontal surface (6) of the wheeled transportation device (1), and an activated engagement member position in which the movable first engagement member (15) engages the frame part (14) of the bed. The autonomous wheeled transportation device (1) comprises a further engagement member (19) located above said at least one substantially horizontal and plane surface (6), and adapted to engage a patient support base of the bed.

Abstract: The present invention provides devices for neck support and correction, for example, pillows, headrests, or cushions, designed to be placed under the head and neck of a person lying in a supine or side-lying position, Such devices are useful for maintaining or improving cervical and/or thoracic spinal curvature and/or alignment and for reducing pain associated with ailments of the neck or cervical vertebrae. Also provided are methods of improving cervical spinal alignment and for treating or ameliorating ailments of the neck or cervical vertebrae.

Abstract: An apparatus includes a harness, at least one brace that may include an articulated frame coupled to the harness, a pre-tensioning device, a lower assembly coupled to the articulated frame, and an energy-transforming mechanism that may be adjusted to a user and may assist with the user's gait. The energy-transforming mechanism may include an energy storage device coupled to the pre-tensioning device via a superior exotendon and coupled to the lower assembly via an inferior exotendon.

Abstract: An ambulatory exoskeleton can be selectively operated in at least two different modes, with one mode constituting an unworn propulsion mode, used when the exoskeleton is not worn by a user, and another mode constituting a default or worn propulsion mode, used when the exoskeleton is worn by a user. With this arrangement, a physical therapist, or other operator, wishing to move an unworn exoskeleton, can balance the unworn exoskeleton, while simultaneously utilizing a control system and actuators of the exoskeleton to propel the unworn exoskeleton. Therefore, the exoskeleton walks by taking steps forward, as commanded by the operator using any of a plurality of input arrangements, while the operator balances and steers the exoskeleton by physically guiding the exoskeleton using a handle or other interaction surface of the exoskeleton.

Abstract: A miniaturised instrument for simulating simultaneous vision by generating masks is provided with a single image-forming optical channel. The instrument comprises: a mask-generating element (EGM) which generates at least two complementary masks, with a temporal frequency of alternation such that when one partially blocks the incident light, the other allows the incident light to partially pass, and vice-versa; an adjustable lens (LA) of variable optical power which generates, with said frequency of alternation, at least two different optical powers corresponding to at least two observation distances. The EGM and the LA are located in a single optical channel via which the incident light circulates, such that each mask of the EGM is temporally synchronised with a power of the LA. The combination of all the masks and optical powers produces, via high-speed temporal fusion, a pupil pattern wherein at least two optical powers corresponding to at least two observation distances are combined.

Abstract: Post-scar formation reduction apparatus comprises a biocompatible scar interface layer, a compressible pressure chamber overlying the scar interface layer, and an at least substantially uniformly compressible pressure element in the pressure chamber which extends over the scar interface layer. The pressure element has a bulk modulus enabling a predetermined uniform or substantially uniform compression of the pressure element in at least a direction perpendicular or substantially perpendicular to the scar interface layer on application of a specific pressure. Evacuator is also provided which at least partially evacuates the pressure chamber, whereby the pressure element is uniformly or substantially uniformly compressed in the direction of the scar interface layer and the pressure chamber positively urges the compressed pressure element towards the scar interface layer.

Abstract: The present invention relates to a method of diagnosing the primary lesions that give rise to a chronic condition or incorrect structure in myofascial units and associated structures in a human patient. The invention also relates to a method of therapeutic treatment of the diagnosed conditions, in particular by application of a variable vacuum stimulus.

Abstract: A muscle fiber excitation system (MFES) to execute multiple displacements in each of a vertical, a medial-lateral, and an anterior-posterior direction. The device may be step-on or wearable. In use, the device stimulates muscles to ameliorate the risk of blood clots and muscular-skeletal decline.

Abstract: A portable hydro-thermal therapy system for use with a vessel for containing water and method for use of the same are disclosed. In one embodiment, the portable hydro-thermal therapy system includes a mobile trailer having a platform to achieve point-to-point haulage thereof. A cool water supply device having inlet and outlet port is mounted on the platform. The cool water supply device includes a water circulation path from the inlet port to the outlet port, a water pump coupled to the water circulation path, and a refrigeration cycle contained within the cool water supply device. A thermostat and water pump may cooperate in combination to provide water between about 50° F. and about 55° F. The water circulation path is thermally proximate to the evaporator coil in order to cool the water being pumped through the water circulation path to and from the vessel by way of inlet and outlet tubing.

Abstract: A sensing and monitoring system can use acupuncture needle-based electrodes for sensing signals from a person and/or delivering stimulation to the person. In various embodiments, the electrodes can include partially insulated acupuncture needles. In various embodiments, the electrodes can include partially insulated or non-insulated acupuncture needles and one or more electrodes incorporated into a needle stopper configured as a guiding tube for an acupuncture needle or integrated into an acupuncture needle.

Abstract: A delivery vehicle for delivering biological products to a surgical site is provided that includes a container for housing the biological product and a fastener that extends from the container for securing the container at a location adjacent to the surgical site. The container is a flexible container having an access that is moveable between an open position and a closed position prior to and after being secured to the surgical site.

Abstract: A record-keeping indicator device, and in particular, to an indicator device associated with medicine containers permits a user to determine the number of doses of medicine taken in a successive interval and on a given day. The indicator device includes a disk having a top and bottom surface. The top surface displays a first set of indicia for the seven days of the week spaced circumferentially around the perimeter. A second set of indicia for the number of doses of medication ingested are evenly spaced between each indicator of the first set. A dial or arrow arm, at the center of the disk, extends outwardly toward the dose indicia and is rotatable about the disk via a turning mechanism. The bottom surface of the disk contains an adhesive material which allows the disk to be attached to any surface of a medicine container.

Abstract: An assembly for a pacifier is provided. The assembly includes a container defining a cavity for housing a bulbous portion of a pacifier, a tether for coupling the container to the pacifier, a spool housed within the container for permitting translation of the pacifier in relation to the container, and a band extending through a slot defined by the container for selectively engaging the assembly to an object or person. Configurations are provided to manage rotation of the spool for ease of use.

Abstract: Radically polymerizable dental material, which contains at least one compound of Formula I: and at least one thermolabile radically polymerizable compound and/or at least one photolabile radically polymerizable compound. The materials are characterized by debonding-on-demand properties.

Abstract: Oral care composition comprise a stannous ion source and a thickener consisting essentially of carrageenan and xanthan gum. A method for treating the oral cavity comprises administering the composition to the oral cavity in a toothpaste.

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

Abstract: A dentifrice composition containing water, calcium-containing abrasive, fluoride ion source, and alkaline metal carbonate with improved fluoride stability.

Abstract: A cosmetic preparation comprising ethylhexyl methoxycrylene and at least 20% by weight, based on the total weight of the preparation, of titanium dioxide and/or zinc oxide.

Abstract: Method for simultaneously and permanently reshaping and coloring keratin fibers, particularly human hairs, in a single process in which the keratinic fibers are first waved by way of a foam-type waving agent (M1) and then lightened or colored by way of a foam-type coloring agent (M2). The permanent wave is simultaneously fixed by the oxidizing agent included in the oxidative dyeing agent. The method according to the invention brings about a uniform waving and coloring result and causes little or no damage to the hair.

Abstract: The present disclosure provides biophotonic compositions and methods useful in phototherapy. In particular, the biophotonic compositions of the present disclosure comprise at least two xanthene dyes. The biophotonic compositions and the method of the disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and other skin conditions.

Abstract: Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.

Abstract: The invention concerns topical compositions based on retinaldehyde, glycylglycine oleamide and, if necessary, delta-tocopheryl-glucopyranoside, and their use in cosmetology and dermatology to combat skin ageing and more particularly light-induced skin ageing.

Abstract: The present invention relates to a method of suppressing coloration of catechins, which contains adding, to catechins, a water-soluble polymer forming a water-insoluble complex with catechins, as well as hydrogel particles containing a water-insoluble complex between catechins and a polymer forming a water-insoluble complex with catechins. Further, the present invention relates to a dentifrice composition containing hydrogel particles containing catechins and a polymer forming a water-insoluble complex with catechins, a binder and water.

Abstract: A method of stimulating adipogenesis in a person's skin is disclosed. The method can include topically applying to skin in need thereof, a composition comprising an effective amount of Commiphora mukul resin or an extract thereof that includes oleo gum resin, wherein adipogenesis in the person's skin is stimulated.

Abstract: A method for preventing or treating tetanus infection in a subject, comprising administering a non-adjuvanted tetanus toxoid vaccine to the skin. The vaccine can be delivered by intradermal injection or microneedle patch and does not require cold storage.

Abstract: Pharmaceutical formulations in suppository form, containing thrombolytic agents, which are able to penetrate rectal mucous, for the treatment of acute hemorrhoid diseases and/or diseases of thrombotic origin.

Abstract: The present invention relates generally to a methods of treating ear infections and clearing excess fluid from Eustachian tubes.

Abstract: The present specification discloses pharmaceutical compositions, methods of preparing such pharmaceutical compositions, and methods and uses of treating a chronic inflammation and/or an inflammatory disease in an individual using such pharmaceutical compositions.

Abstract: The present disclosure relates to a method for the preparation of a nanosuspension of at least one natural material, wherein the method comprises the steps of (a) providing at least one natural material having a particle size (D90) of less than 320 ?m; (b) dispersing said at least one natural material of step (a) in a solvent; and (c) milling the dispersion of step (b) to a particle size (D90) of below 1000 nm. The nanosuspension is useful for the preparation of a medicament.