Abstract: A breast pump (10) includes a breast pump cup (11) that is mounted on a breast, a suction pump (21) that absorbs fluid from the breast side of the breast pump cup (11), a detector (32) that detects temporal change in a sucked state of the breast by the breast pump cup (11), and an indicator (39) and a pattern adjusting unit (33) that perform processing based on the temporal change in the sucked state, which has been detected by the detector (32).

Abstract: An implantable connector assembly (14) for communicating an element to an implantable device (12) within a patient (20) comprises a plug (16), a receptacle (18), and a pair of communication structures (72, 108). The plug (16) includes a plunger body (64). The receptacle (18) includes a sleeve (98) and a stopper (114). The sleeve (98) defines an opening (104), and the stopper (114) is resiliently mounted within the sleeve (98) to cover and fluidly seal the opening (104). The pair of communication structures (72, 108) is positioned respectively on the plunger body (64) and the sleeve (98). One of the communication structures (72, 108) connects to a source and the other communication structure (108, 72) connects to the implantable device (12). The plunger body (64) inserts into the sleeve (98) to displace the stopper (114) and couple the pair of communication structures (72, 108) for communication of the element therebetween.

Abstract: A ventricular assist device for intraventricular placement inside a heart of a mammalian subject includes a pump including a housing having an inlet end, an inlet at the inlet end, and an outlet. The pump further includes a moveable element disposed in the pump housing for pumping blood from the inlet to the outlet. A base member is included as well as a spacer member connected to the pump housing and the base member. The base member is positioned a distance from the inlet end of the pump housing to define a gap therebetween. One or more sensor elements are mounted to at least one from the group consisting of the base member and the housing, the one or more sensor elements being configured to measure one or more blood parameters prevailing within the gap during operation of the pump.

Abstract: An implant device includes a housing and an energy receiving element disposed in the housing. The energy receiving element is configured to be electrically connected to an energy-consuming device. The implant device is configured to be mounted within a body of a human or non-human animal. The housing includes a feature configured to be accessible through skin of the animal and to receive a corresponding mating member of an external charger including an energy transmitting element. The energy receiving element is configured to receive energy wirelessly from the energy transmitting element when the external charger is mated with the housing.

Abstract: Extracorporeal blood treatment apparatus (1) and methods as described herein involve control of blood line pressure utilizing a non-invasive pressure sensor (16).

Abstract: A system associated with a medical treatment device for detecting a condition of a patient includes an input device including at least a camera or a microphone. The system also includes a medical treatment device with a controller/classifier and at least one of flow controller, a pump, and/or an alarm output. The controller/classifier has at least a video-image processor or an audio processor configured to recognize a face and a body or to recognize changes in skin color, facial expression, or body position. The controller/classifier may also recognize speech and classify predefined normal and irregular sound patterns, and output state data corresponding thereto. The controller/classifier is connected to apply the state data to the at least one flow controller, pump, and/or alarm output. The controller/classifier is further adapted to control the at least one flow controller, pump, and/or alarm output responsively to the state data.

Abstract: A blood reservoir may be used in combination with other elements such as a heart lung machine (HLM), oxygenator, heat exchanger, arterial filter and the like to form an extracorporeal blood circuit that may be employed in a procedure such as a bypass procedure. The blood reservoir may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).

Abstract: The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

Abstract: A blood purification column includes an adsorbent and a casing whose two ends are open ends, wherein the adsorbent is housed inside the casing, and wherein one of two casing ends is a blood inflow-side end portion and another is a blood outflow-side end portion, and wherein a filter is disposed at the blood inflow-side end portion and/or the blood outflow-side end portion of the casing, and wherein the filter satisfies (1)-(3): (1) an opening rate thereof is greater than or equal to 5% and less than or equal to 80%; (2) an equivalent diameter of an aperture thereof is greater than or equal to 1 ?m and less than or equal to 5000 ?m; (3) a ratio of the equivalent diameter of the aperture thereof to an average circle equivalent diameter of void spaces of the adsorbent is greater than or equal to 45%.

Abstract: A method for performing a photopheresis procedure is provided comprising collecting MNCs in a suspension comprising RBCs and plasma and lysing the red blood cells in the solution, preferably by combining the suspension with a solution to cause lysis. In one example, the solution for causing lysis of the red blood cells comprises ammonium chloride, and the suspension including the ammonium chloride is incubated to cause lysing. After lysing, the suspension may be washed to remove plasma and hemoglobin freed by the lysis of the red blood cells, and an ultraviolet light activated substance is added to the suspension. The suspension is then irradiated with ultraviolet light.

Abstract: A body-wall-contact-type water tank (12) is equipped with: a water-tank body for storing a fluid to be supplied into a body cavity, and positioned so as to contact a body wall (120); a through-hole which conveys the fluid stored in the water-tank body into the body cavity via an incision formed in the body wall (120), and which is formed in the bottom section of the water-tank body; and a connecting means for connecting, in a fluid-tight manner, the water-tank body to the body wall (120) and/or to a retractor (110) attached to the incision.

Abstract: A device for delivering a beneficial agent is provided and generally includes a cassette, a pump, and a delivery tube. The pump includes a pump housing containing a pump assembly having a fluid drive component. The pump housing has a receiving region disposed proximate the fluid drive component and further includes a rear closure portion. The rear closure portion includes a membrane disposed between the receiving region and the fluid drive component. The cassette includes a cassette housing, which has a cassette body region defining a fluid reservoir chamber therein. The cassette further includes a cassette base region having a boundary configured to be received by the receiving region.

Abstract: A system and method provide for enhanced reliability and safety of programming and/or operating a medical device, such as an infusion pump. A safety processor can check whether an operating command is within acceptable parameters.

Abstract: Systems and methods for automatic flow termination for fluid delivery, including a housing configured for coupling a fluid delivery tube to a needle configured for subcutaneous delivery of fluid within a tissue of a patient and a spring-loaded activation mechanism having a first orientation corresponding to a condition where the housing is disposed substantially adjacent to the tissue and the needle lodged within the tissue and a second orientation corresponding to a condition where the housing is disposed away from the tissue or the needle being dislodged from the tissue. A flow termination mechanism is coupled to the activation mechanism and having an open configuration allowing flow from the fluid delivery tube to the needle when the activation mechanism is in the first orientation and a closed configuration substantially terminating flow from the fluid delivery tube to the needle when the activation mechanism is in the second orientation.

Abstract: A drug delivery device for delivery of medicament having a delivery pump system and a cartridge system, the delivery pump system operating electromagnetically by driving two disk magnets that are housed within pump body inserts of the cartridge system. The displacement of the magnets and an elastomer membrane placed between the magnets of the cartridge system results in a volumetric change within two reservoirs and the flow of medicaments. The medicament flows from the reservoirs to the inlet/outlet members via the pump body inserts and discharged to a patient user's body through an infusion set.

Abstract: Methods and systems are presented for monitoring a clinical procedure using regional blood oxygen saturation (rSO2) of a subject. The rSO2 of a subject is monitored, and clinical information is received, indicating that the subject is undergoing a clinical procedure (e.g., an infusion pump procedure for sodium nitroprusside administration). A change in the rSO2 of the subject is detected, which may be indicative of a circulatory system impairment (e.g., elevated venous oxygen saturation) caused by the clinical procedure. Status information, which may be indicative of an increased risk of a physiological event (e.g., cyanide toxicity) is determined for the subject based on the clinical information and the detected change in the rSO2 of the subject. Corrective actions may be triggered based on the status information in order to reduce the increased risk. The corrective actions may be implemented as smart prompt or closed loop systems.

Abstract: A de-noising algorithm is executed dynamically as data is received to generate and update a set of candidate solutions. Each candidate solution is a representation of the data using one or more line segments, and each line segment is fitted to the data within the time period that the segment spans. During each iteration of the algorithm, one candidate solution is identified as a best solution, and properties of the best solution are utilized to dynamically compute properties of the data. To limit the number of active candidate solutions and the corresponding processing power required to update and evaluate them, candidate solutions that fall too far behind the best candidate solution are eliminated from consideration. The de-noising algorithm finds particular utility in the context of a load cell signal that is representative of a weight of an intravenous fluid container.

Abstract: A drive member for driving a piston rod in a drug delivery device is provided. The drive member is configured to be driven in a rotational movement by an actuating member. The drive member comprises a track for transmitting a driving load from the actuating member to the drive member. The track comprises both sections running in a distal and sections running in a proximal direction of the drive member. Moreover, a drug delivery device comprising such a drive member is provided.

Abstract: A method of delivering high pressure medication injections, the method comprising storing a medicament in a cartridge, engaging a lever gear in a lever assembly to a rack, rotating a lever arm in said lever assembly that is connected to said lever gear, moving said rack to move a stopper through said cartridge upon rotation of said lever arm, expelling a medicament dose from said cartridge via movement of said stopper, and injecting said medicament dose through a needle that communicates with said cartridge.

Abstract: A medial assembly comprises a logging first unit adapted to be mounted on a drug delivery device second unit from a fully un-mounted to a fully mounted position along a path. The first unit comprises a switch operatable between an off- and an on-state when the first unit is mounted on the second unit, the switch being in the on-state when the first unit is mounted within a first distance from the fully mounted position, and in the off-state when the first unit is mounted outside the first distance from the fully mounted position, and a snap lock operatable from an initial state through an expanded state to a snap-in state when the first unit is mounted on the second unit, the snap lock being in the snap-in state when the first unit is mounted within a second distance from the fully mounted position, the second distance being shorter than the first distance. By this arrangement it is ensured that the switch will be in the on-state before the snap lock is in the snap-in state.

Abstract: A syringe having a mechanical ejection mechanism. The ejection mechanism includes an actuator and a rotational gear. The actuator has a retractable pawl configured to engage the gear when the actuator is displaced from a non-depressed position into a depressed position. Displacement of the actuator causes the gear to rotate by a predetermined angle. The rotation of the gear is translated into linear displacement of the plunger within the barrel, thereby ejecting a predetermined amount of solution from the barrel.

Abstract: A dose control mechanism for a syringe includes an engaging screw thread arrangement between an exterior surface of a plunger and a longitudinally extending channel of a housing. The engaging screw thread arrangement includes at least one thread segment and a pitch guide including a variable pitch thread. At least a portion of the longitudinally extending channel of the housing including one of the pitch guide and the at least one thread segment, and the plunger includes the other of the pitch guide and the at least one thread segment. The plunger resides at least partially within the housing with the at least one thread segment engaged with the pitch guide. An accurate dose drug delivery syringe includes such a dose control mechanism, a barrel, a plunger seal, and a barrel adapter assembly having a barrel tip and a needle.

Abstract: A medicament delivery device is shown for the administration of one or more drug agents. The device has a priming mode and a drug delivery mode for administering delivery of the one or more drug agents. The device comprises a controller configured to set the device in a priming mode when one or more predetermined states of the device are identified and to disable the drug delivery mode during said predetermined state(s). When states of the device are different from said predetermined states, the controller can set the device in the drug delivery mode. A priming mode may still be enabled through a user interface.

Abstract: Disclosed herein is a syringe device comprises (a) an outer housing, (b) a barrel, (c) a stopper, and (d) a plunger with one or more grooves.

Abstract: A drug delivery device (1) comprises a housing and an expelling assembly adapted to expel a dose of drug from a cartridge (380). The expelling assembly comprises a drive spring (135) which in an energized state is adapted to drive the expelling assembly, a rotating component (550,650) adapted to rotate relative to an axis of rotation during expelling of a dose of drug, and user actuated release means (191, 190) for releasing the drive spring to thereby expel a dose of drug. The device is provided with a brake element (575, 675) being moveable in a plane generally perpendicular to the axis of rotation, the brake element being adapted to engage the rotating component such that during rotation thereof the brake element is moved back and forth, whereby the brake element provides a braking action on the rotating component.

Abstract: An injection device includes a housing, a dose setting member being operable in a first direction to set a desired dose to be dispensed, and a piston rod being adapted to cooperate with a piston so as to cause a set dose to be injected from a cartridge. Further, a first part and a second part of the injection device are provided, which are adapted to perform a relative rotational movement with respect to each other during dispensing of a dose, and which are adapted to provide a non-visual feedback signal to a user only at the end of dispensing of a set dose. The dose setting member is further operable in a second direction which is opposite to the first direction to cancel a set dose. A third part is movable between a dose setting or cancelling position and a dose dispensing position relative to the first part and/or the second part, which third part contacts the first part and/or the second part in its dose setting or cancelling position or in its dose dispensing position.

Abstract: A medical needle cover arrangement for a single-use syringe having a medical needle with a sharp tip, the needle being mounted on the syringe to project forwardly from a needle hub. A sleeve forming a part of a safety device is mounted on the syringe. The sleeve is arranged for axial movement with respect to the needle from an initial shielding position to a non-shielding position, the sleeve being blocked against forward movement with respect to the syringe from its initial shielding position. A soft needle cover overlies the needle with the sharp tip of the needle sealed by the cover. The rear end of the soft needle cover and the forward end of the syringe hub are profiled with complementary engaging surfaces. The cover has a step part-way between its ends, the step being engaged by an internal abutment at the forward end of the sleeve, to resist movement of the cover forwardly away from the syringe hub and so maintain a seal between the cover and hub.

Abstract: A replaceable needle assembly is provided for a retractable, prefilled syringe comprising a barrel having a mounting member and a plunger, whereby the retractable needle can be replaced by a user without affecting the retraction mechanism. The replaceable needle assembly comprises a needle fitted to a retractable needle mount and a needle retainer. The needle mount is removably, screw-threadedly mountable to the mounting member of the barrel. The needle retainer comprises a plurality of fingers that releasably engage the retractable needle to thereby prevent inadvertent retraction of the retractable needle before engagement by the plunger. The plunger comprises a plunger seal comprising an outer member and an inner member that engages the needle for spring-driven retraction. At the end of retraction, a lock is formed between the plunger and barrel to prevent re-use of the syringe.

Abstract: The invention relates to an injection device for self-administration of doses of a liquid drug. The injection device carries a needle cannula (15) which is concealed by a telescopically movable shield (20). Further a stopping means (30) interconnects the shield with the helical rotatable scale sleeve (25) such that the shield can only be operated proximally when the scale sleeve is rotated away from its zero position. Once the scale sleeve returns to its zero position during expelling of the dose, the shield and the stopping means is allowed to slide distally and thus return to the locked position.

Abstract: Inner ear treatment delivery devices and methods are disclosed. The device includes a pressurized container filled with a content, a control mechanism within the pressurized container, a nozzle coupled to the control valve, a microprocessor adapted to operate the control valve, and a power source providing energy to the device. The device administers at least one dose of the content to a patient's inner ear.

Abstract: A device for providing positive expiratory pressure therapy to a patient wherein exhaled air is at a comparatively higher pressure than atmospheric pressure, said device including a container to hold liquid, an air inlet means to allow entry of air into the container and an air outlet to allow air to vent from the container. The air inlet means includes a conduit to discharge the exhaled air. The conduit is fixed in position so that the exhaled air is discharged at or substantially adjacent the base of the container. In use liquid is introduced into the container to a predetermined level and the bottom of the conduit is below the predetermined level of liquid to provide a desired level of positive pressure and the air outlet is above the predetermined level of liquid.

Abstract: Systems and methods for providing respiratory therapy with varying flow rates are disclosed. A system comprises a source of breathing gas, a patient interface, and a flow control device. The flow control device is configured to automatically change a rate of the flow of breathing gas. The flow control device may vary the rate of the flow of breathing gas at a frequency slower than a frequency of breathing of the patient. A method comprises coupling a patient interface to the patient, providing the flow of breathing gas to an inlet port of the patient interface, and automatically changing a rate of the flow of breathing gas with a flow control device in communication with the flow of breathing gas. The method may also comprise varying the rate of the flow of breathing gas at a frequency slower than a frequency of breathing of the patient.

Abstract: Supraglottic airway devices such as the laryngeal mask airway (LMA) device are used in anesthesia practice to maintain an open airway in patients undergoing anesthesia. LMA devices are also used as a conduit for the insertion of endotracheal tubes (ETT) through the laryngeal opening into the patient's trachea (endotracheal intubation). In scenarios where the conventional method of tracheal intubation is challenging or not possible, modified LMA devices have played a pivotal role for several decades. However, present embodiments of LMA devices suffer from significant shortcomings that the device in this patent aims to address. Currently available modified LMA devices have many limitations when used as a conduit for the insertion of ETT. The apparatus shown the present description aims to address those major limitations and to significantly improve the success rate of tracheal intubation.

Abstract: A nasopharyngeal cannula comprising a body formed by a tubular portion that is curved so as to be inserted into a patient's nostril and a collar for resting on the base of the patient's nostril is described. The cannula also comprises a main channel forming a fluid passage between the collar and the tubular portion of the body and two auxiliary channels formed in the body and extending from the collar into the main channel. Each auxiliary channel opens into the collar at an inlet/outlet port oriented radially in relation to the axis of the main channel such as to be oriented laterally on each side of the patient's nostril when the cannula is in place on the patient.

Abstract: A mask to administer breathable gas to a user may include a body structure having a connection opening to connect to a line device to deliver the breathable gas; a sealing lip device to seal against the user's face, the sealing lip device joined to the body structure, and the sealing lip device having an upper bridge portion structured to cross the bridge of the user's nose in use, a pair of side portions structured to be positioned along corresponding side surfaces of the user's nose in use, and a lower bridge portion structured to cross the user's upper lip or chin region in use; and a pair of beadlike gel cushions, each positioned in a corresponding one of the side portions.

Abstract: A patient interface device includes a frame member and a cushion having a main body, a sealing portion, and first and second posts extending from the main body. The frame member defines a first orifice and a second orifice. The first post of the cushion is rotateably received within the first orifice and the second post is rotateably received within the second orifice in a manner that permits the cushion to rotate relative to the frame member.

Abstract: A medical tube has a tube wall defining a passageway for transportation of gases and further has a first end and a second end. At least one end of the medical tube comprises one or more of a pre-formed pneumatic port component, a pre-formed electrical port component, and a pre-formed sensor port component. A cuff is over-molded about and thereby connects the pneumatic port component, the electrical port component, and/or the sensor port component and at least a portion of the tube end.

Abstract: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4, activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.

Abstract: A tub for a humidifier includes an inner tub configured to hold a supply of water; an outer tub configured to receive the inner tub, the outer tub including a bottom and a cavity being formed between the bottom and the inner tub when the inner tub is received in the inner tub; and a valve configured to control a flow of the supply of water from the inner tub to the cavity. The valve is closed to prevent the flow when the inner tub is received in a first position in the outer tub and open to permit the flow when the inner tub is received in a second position in the outer tub.

Abstract: The present invention provides a new inhaler device for the storage and administration of inhalable liquids to a patient, such as halogenated volatile liquids, particularly methoxyflurane for use as an analgesic, the device having one or more advantages or improvements over known inhalers.

Abstract: A valve comprises a housing in which a movable valve element having first and second valve members is disposed. A plurality of ports are disposed in the housing, and first and second seal portions are connected to the housing. At least one of the first seal portion and the first valve member is deformable such that, when only the first seal portion is in a sealed configuration with the first valve member, deformation allows the second seal portion to be brought into a sealed configuration with the second valve member, and/or at least one the second seal portion and the second valve member is deformable such that, when only the second seal portion is in a sealed configuration with the second valve member, deformation allows the first seal portion to be brought into a sealed configuration with the first valve member.

Abstract: A valve with an internal member is disclosed which allows exhaled carbon dioxide to escape from a breathing circuit when the circuit gas pressure drops below a threshold pressure. The valve operates by occluding one or more ports under a relatively high pressure and opening the one or more ports under a relatively low pressure. The internal member is attached to the body of the valve at two or more locations on the internal member. The internal member moves in a direction perpendicular to the gas flow through the valve.

Abstract: Disclosed is a method of enhancing exposure therapy comprising providing an exposure therapy to a patient and stimulating the patient's vagus nerve at the same time as the exposure therapy. Also disclosed is a post-traumatic stress disorder therapy method comprising providing an exposure event to a patient and stimulating the patient's vagus nerve during the exposure event. Also disclosed is a phobia disorder therapy method comprising providing an extinction event to a patient and stimulating the patient's vagus nerve during the exposure event. Also disclosed is an obsessive compulsive disorder therapy method comprising providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event. Also disclosed is an addiction disorder therapy method comprising providing a therapy event to a patient and stimulating the patient's vagus nerve during the therapy event.

Abstract: A catheter assembly includes an outer catheter and an inner catheter. The inner catheter has an accommodation unit which can be positioned on a farther distal side than an outer catheter body in a state where an inner catheter body is inserted into the outer catheter body, extends in a proximal direction from the inner catheter body, and can accommodate an outer catheter distal portion so as to surround an outer circumference thereof in a state where the outer catheter distal portion formed at a distal end of the outer catheter body is reduced in diameter. The outer catheter distal portion can be separated from the accommodation unit and can expand in diameter by moving the inner catheter body in a distal end direction relatively with respect to the outer catheter body from a state of being accommodated in the accommodation unit.

Abstract: A catheter has a proximal portion of relatively larger central lumen diameter and outer diameter, and a distal portion of relatively smaller central lumen diameter and outer diameter, the two portions being integral with one another so that cells delivered into the central lumen of the proximal portion will flow through and exit the central lumen of the distal portion, encountering a constriction at the junction of the two portions, for infusion into body tissue at a predetermined target site when the catheter is inserted into a designated natural body vessel or duct leading to the target site. The cells are delivered in a fluid under pressure through a central lumen of the catheter to exit distally from the lumen at the target site, and meander of exiting fluid pressure from a predetermined value is minimized by adjusting the fluid pressure at the point of entry into the catheter's central lumen accordingly.

Abstract: Apparatus and methods are described including inserting a catheter into a subject's body via a vein of the subject's groin. The catheter is advanced distally such that a distal end of the catheter is disposed inside the subject's renal vein. Respective stabilizing portions of the catheter stabilize the catheter by being in contact with inner walls of, respectively, an iliac vein of the subject, and a vena cava of the subject. Subsequently, a medical device is deployed inside the renal vein by retracting the distal end of the catheter, such that the distal end of the catheter is in a retracted state, in which the respective stabilizing portions of the catheter still stabilize the catheter by being in contact with the inner walls of, respectively, the subject's iliac vein and the subject's vena cava. Other applications are also described.

Abstract: Various devices, systems, and methodologies are disclosed for delivering a chemical agent to tissue, e.g., for delivering an anti-restenotic agent to tissue comprising a wall of a blood vessel. In one embodiment of the disclosure, a delivery member is disclosed comprising a body that includes a plurality of discrete, separable sections, wherein each section includes a housing defining an internal cavity, and a penetrating member that extends from the housing.

Abstract: A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

Abstract: Treating a treatment area in the vasculature includes a first catheter adapted for positioning at the treatment area, said first catheter including a first balloon having a transient radiopaque material corresponding to the treatment area. A second catheter adapted for positioning at the treatment area includes a treatment that substantially matches the transient radiopaque material, preferably so that the length and/or position of the treatment corresponds to the length and/or position of the transient radiopaque material. Related kits, assemblies, and methods are also described.

Abstract: An apparatus (100) for guiding a catheter within a patient's body, the apparatus comprising: a first wire (112) having longitudinally spaced distal and proximal first wire ends (114,116)) separated by a first wire body; a catheter (102) having longitudinally spaced distal and proximal catheter ends (130,132) separated by a catheter body having a catheter lumen (136) extending longitudinally therethrough between the distal and proximal catheter ends, the catheter having a catheter aperture (138) extending substantially laterally through the catheter body at a location proximally adjacent to the distal catheter end; a second wire (120) having longitudinally spaced distal and proximal second wire ends (122,124) separated by a second wire body.