Patents Issued in March 21, 2019
  • Publication number: 20190083681
    Abstract: The present invention relates to a porous polymer material (or scaffold), and more particularly to a polymer-ceramic composite having interconnected pores and a porosity of about 50% to 90%. The scaffold is bioresorbable and exhibits advantageous mechanical properties that mimic those found in natural bone. Methods of preparing the scaffolds and using them in skeletal tissue engineering applications (e.g., as bone grafts to repair osteochondral defects and ligaments) is also described.
    Type: Application
    Filed: February 28, 2017
    Publication date: March 21, 2019
    Applicant: EpiBone, Inc.
    Inventors: Sarindr Bhumiratana, Eric Jeffries, Melanie Reschke
  • Publication number: 20190083682
    Abstract: The invention relates to process for creating catheters that are coated with these layers of elastomeric polymeric coating with an antitoxic agent, antimicrobial resin, affixed to the surface of said polymeric coating. The method of coating an elastomeric material on the exterior and/or the interior includes: (a) providing a base elastomer comprised of an elastomeric polymer; (b) dipping the elastomer in a second organic solution containing a polymer to form a secondary coating over the barrier coating; (d) coating the elastomer with suspension containing polyiodinated resin particulate in an organic solvent to anchor the particulates to the secondary coating; and (e) drying the elastomer.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 21, 2019
    Inventors: Kermit R. Littleton, Lynn R. Detlor, Albert Rego
  • Publication number: 20190083683
    Abstract: The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.
    Type: Application
    Filed: April 17, 2018
    Publication date: March 21, 2019
    Inventors: Gordon F. JANKO, Herbert R. RADISCH, Thomas A. TROZERA
  • Publication number: 20190083684
    Abstract: The disclosed medical examination glove comprises natural or nitrile rubber latex, and a water soluble singlet oxygen generator. The glove can be manufactured by contacting a glove former with a coagulant solution comprising divalent calcium cations and carbonate particles and a water soluble singlet oxygen generator and then contacting the glove former with a natural or nitrile rubber latex dispersion.
    Type: Application
    Filed: February 28, 2017
    Publication date: March 21, 2019
    Applicant: Chemical Intelligence Limited
    Inventors: Robert T. GROS, Paul Wight
  • Publication number: 20190083685
    Abstract: Disclosed is a degradable zinc base alloy implant material comprising, by mass percentage content, 0.01 wt % to 14 wt % of Fe, 0 wt % to 13 wt % of functional elements and the remainder being Zn and a preparation method and use thereof. During preparation, Zn, Fe, and the functional elements are homogeneously mixed and placed into a high-purity graphite crucible and smelted together under a mixed gas atmosphere of SF6 and CO2. The mechanical properties of the zinc base alloy implant material have been significantly improved, so that the implant material is easy to process and shape, and so that the properties of strength and plasticity, etc., meet the basic requirements of human body implant materials, such as vascular stents, orthopedic internal fixation systems, and the like.
    Type: Application
    Filed: March 10, 2017
    Publication date: March 21, 2019
    Inventors: Haijun ZHANG, Luning WANG, Chao ZHOU, Yuxia YIN, Shoutao LU, Yanwei ZHAO
  • Publication number: 20190083686
    Abstract: In one aspect, the present invention relates to a wound care system. The wound care system includes a power unit and a processor coupled to the power unit. An ultra-violet light-emitting diode array is electrically coupled to the processor. A thermoelectric element is thermally exposed to the ultra-violet light-emitting diode array. A probe is optically coupled to the ultra-violet light-emitting diode array. The thermoelectric element cools the ultra-violet light emitting diode array thereby optimizing the ultra-violet light emitting diode array.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 21, 2019
    Inventor: Tony QUISENBERRY
  • Publication number: 20190083687
    Abstract: The invention relates to a device for rinsing a body cavity, wherein a pressure sensor for determining the actual pressure in the body cavity is provided, said pressure sensor being arranged in the drainage line (8).
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Inventors: Martin Reuther, Matthias Stiller, Thomas Merzhauser
  • Publication number: 20190083688
    Abstract: A sound suppression system for reducing or eliminating sound produced by the operation of a breast vacuum pump includes a sound suppressing muffler assembly having an air entry port adapted to communicate with an air outlet port of a vacuum pump or other air flow generating device. The sound suppressing muffler assembly also includes a muffler housing defining an internal space communicating with the air entry port, and an opening in the housing leading to atmosphere. The muffler housing has a tortuous air path in the muffler housing. In one embodiment, sound absorbing porous foam structure is disposed in the tortuous air path. The at least one sound absorbing porous structure absorbs sound energy from the air as the air moves through the at least one air path toward the opening in the muffler housing. In further embodiments, a tortuous air path is provided between an air entry port and an opening to atmosphere in the muffler assembly.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 21, 2019
    Inventors: Ben Sutton, Dave Paul, Dan Garbez
  • Publication number: 20190083689
    Abstract: A circulatory assist apparatus comprising: an inflatable pumping balloon having a proximal end joined to an elongated balloon catheter, the balloon catheter having a distal end joined to the pumping balloon and a proximal end, separated from the distal end by a length sufficient to extend from within a circulatory lumen to the outside of a patient's body, for receiving positive and negative pressure pulses from a pump to inflate and deflate the pumping balloon; and a radially expandable frame, mounted on one of a segment extending distally from the pumping balloon, the balloon catheter, and a sleeve tube surrounding the balloon catheter. The expandable frame is manipulate to expand within the circulatory lumen, and functions to space apart the inflatable balloon from the circulatory lumen, having a first diameter in a collapsed configuration for intraluminal delivery and a second, larger diameter in an expanded configuration achieved by said manipulation.
    Type: Application
    Filed: June 12, 2018
    Publication date: March 21, 2019
    Inventor: Constantinos ANAGNOSTOPOULOS
  • Publication number: 20190083690
    Abstract: A blood pump system including a blood pump, an intravascular flow cannula, and a pressure sensor. The intravascular flow cannula is in flow communication with the blood pump and has a distal end portion distally from the blood pump and a proximal end portion closer to the blood pump. The intravascular flow cannula has at least one blood flow through opening at its distal end portion for blood to enter or exit the flow cannula. The blood flow through opening has a borderline surrounding the through opening. The pressure sensor is configured radially within the flow cannula and borders a proximal portion of the borderline.
    Type: Application
    Filed: February 10, 2017
    Publication date: March 21, 2019
    Inventors: Thorsten Siess, Frank Kirchhoff, Christoph Nix
  • Publication number: 20190083691
    Abstract: A unit (10) for preparing at least one hemodialysis concentrates solution (CH), the solution comprising solid water-soluble materials comprising at least sodium chloride (NaCl), potassium chloride (KCl), calcium chloride (CaCl2) and magnesium chloride (MgCl2). This unit has a modular structure and includes the following modules: a sampling module (MPRE) to take at least a sample of each of the raw materials to be dissolved in a volume of purified water, a laboratory module (MLAB) arranged to analyze each of the samples of said raw material to control compliance and quality, a weighing module (MPES) to determine the quantity in weight of the raw material to be introduced in the predetermined volume of purified water, a solution preparation module (MPRE) to introduce and dissolve the quantity in weight of raw material in the predetermined volume of purified water, and at least one module (MCON) for packaging the prepare hemodialysis concentrate solution.
    Type: Application
    Filed: March 17, 2017
    Publication date: March 21, 2019
    Inventors: Henri GAUTHIER, Nicolas TILATTI, Philippe COURTIADE
  • Publication number: 20190083692
    Abstract: A method for operating a dialysis machine to conduct a dialysis treatment on a patient (e.g., a peritoneal dialysis machine) may include transferring dialysate from a first bag, and automatically determining the dialysate from the first bag has completely transferred. After determining the dialysate has completely transferred from the first bag, switching from the first bag to a second bag of dialysate. The method may further include transferring dialysate from the second bag in response to the detection of the completed transfer of the first bag, and automatically determining the dialysate from the second bag has completely transferred. The method may further include determining if the respective first or second bag has completely transferred by comparing a dialysate bag volume transferred to the patient to a detected volume of the respective first or second bag. Systems with dialysis machines for performing such a method are disclosed as well.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 21, 2019
    Inventors: Kulwinder S. Plahey, John A. Biewer
  • Publication number: 20190083693
    Abstract: Dialysis machines and methods for operating dialysis machines (e.g., peritoneal dialysis machines) may include delivering dialysate to a patient and detecting a temperature of a volume of the dialysate, an air content of the dialysate volume, or another condition, or combinations thereof, wherein the detected temperature of the dialysate volume is compared to a predetermined maximum temperature, the detected air content of the dialysate volume is compared to a predetermined maximum air content and the detected other condition generates a signal. The volume of dialysate may be diverted in response to the detected temperature exceeding the predetermined maximum temperature, the air content exceeding the predetermined maximum air content, or the other condition generated signal, or combinations thereof.
    Type: Application
    Filed: September 21, 2017
    Publication date: March 21, 2019
    Inventors: John A. Biewer, Kulwinder S. Plahey
  • Publication number: 20190083694
    Abstract: The invention relates to dialysis device having an extracorporeal blood circuit which has an arterial line having a blood pump and an arterial needle for connection to a patient, a venous line having a venous needle for connection to a patient and a dialyzer arranged between the arterial line and the venous line and having a blood chamber and a dialysis fluid chamber, wherein the dialysis device furthermore has a control unit, wherein the dialysis device furthermore has an extracorporeal blood pressure sensor which is arranged at the suction side of the blood pump and wherein the control unit is configured such that a signal output takes place which indicates the presence of recirculation when a change in the signal of the sensor following a trigger event exceeds a threshold value.
    Type: Application
    Filed: December 23, 2016
    Publication date: March 21, 2019
    Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Pascal KOPPERSCHMIDT, Alfred GAGEL
  • Publication number: 20190083695
    Abstract: A percutaneous catheter provides an adjustable diameter in order to reduce pressure loss, maintain a required flow, and avoid increasing a load to the patient. A catheter tube is formed of braided wires in an intersecting manner and extends in an axial direction. A distal tip is affixed to a distal side of the catheter tube and is configured to engaged a distal end of a dilator. The catheter tube includes a non-coated portion on a proximal side of the distal tip and a coated portion embedded in a resin material. An inner diameter of the non-coated portion is larger than an outer diameter of the dilator. When the dilator is fully inserted through the percutaneous catheter, the non-coated portion expands in the axial direction, reducing its in inner diameter so that an inner surface of the non-coated portion comes into tight contact with an outer surface of the dilator.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 21, 2019
    Inventor: Kenji Yokoyama
  • Publication number: 20190083696
    Abstract: A platelet collection method includes a step of accommodating whole blood in a first chamber (44) and performing centrifugal separation, a step of transferring a buffy coat resulting from the centrifugal separation to a second chamber (50), and a step of performing centrifugal separation on the buffy coat. Subsequently, a step of transferring a platelet-containing component resulting from the centrifugal separation to a third chamber (52) and a step of performing centrifugal separation on the platelet-containing component are executed. Also performed in the collection method are a step of introducing a platelet additive solution into the third chamber (52) and replacing plasma resulting from the centrifugal separation and a step of collecting platelets remaining in the third chamber (52) along with the platelet additive solution.
    Type: Application
    Filed: August 25, 2016
    Publication date: March 21, 2019
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Masatsugu IGARASHI
  • Publication number: 20190083697
    Abstract: A syringe nest assembly includes a base having a first surface and an opposing second surface and a first plate movably coupled to the base. The base includes a plurality of nesting units extending upwardly away from the first surface of the base. Each nesting unit includes a hollow body having a first open end distal from the first surface of the base and an opposing second open end. The first plate has a first surface and an opposing second surface. The first plate includes a plurality of apertures extending from the first surface to the second surface of the first plate. Each aperture of the first plate is generally aligned with a respective nesting unit of the base.
    Type: Application
    Filed: February 8, 2017
    Publication date: March 21, 2019
    Inventors: Christopher EVANS, Brian COSTELLO, Raymond PROTASIEWICZ, Christopher GIEDA
  • Publication number: 20190083698
    Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.
    Type: Application
    Filed: December 11, 2017
    Publication date: March 21, 2019
    Inventors: Richard J. Lanigan, Bright Chong Khuang Foo, Dean Kamen
  • Publication number: 20190083699
    Abstract: A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.
    Type: Application
    Filed: March 3, 2017
    Publication date: March 21, 2019
    Inventors: MICHAEL SPOHN, RALPH SCHRIVER, ARTHUR UBER, RONALD HELLER, KEVIN COWAN, BARRY TUCKER, EDWARD RHINEHART, TIMOTHY NEWING
  • Publication number: 20190083700
    Abstract: A one-time use plastic disposable lockbox enclosing an infusion system including the infusion device, method of delivery such as tubing, and source reservoir such as a fluid bag or syringe is provided. The lockbox includes first and second thermoplastic shells joinable along a separation plane to define a housing. The housing carries an IV bag volume abutting a periphery of a filled standard IV bag to restrain movement of that IV bag along the separation plane and a pump volume abutting a periphery of an IV pump to restrain movement of that IV pump along the separation plane. A channel extends between the pump volume and an exterior of the housing to allow egress of a standard IV line from the housing.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 21, 2019
    Inventor: Frederick Lee
  • Publication number: 20190083701
    Abstract: The present disclosure relates to a drug delivery device for dispensing of a liquid medicament, the device comprising: a housing to accommodate a cartridge filled with the medicament and having a piston slidably displaced inside the cartridge and sealing a proximal end of the cartridge, at least one resilient member having a first end arranged at an inside facing side wall portion of the housing and having a second end (opposite to the first end to abut with the piston of the cartridge.
    Type: Application
    Filed: September 5, 2016
    Publication date: March 21, 2019
    Inventor: Andreas Bode
  • Publication number: 20190083702
    Abstract: An adhesive patch for a drug delivery device with a bacteria impermeable sterility margin surrounding an edge surface of the adhesive patch is disclosed, as well as a drug delivery device fixed to such an adhesive patch and a method of assembling a drug delivery device with such an adhesive patch. In some arrangements, the sterility margin is attached to or integral with a lower liner on a lower surface of the adhesive patch. In other arrangements, the sterility margin is attached to or integral with an upper liner on an upper surface of the adhesive patch.
    Type: Application
    Filed: July 31, 2018
    Publication date: March 21, 2019
    Inventors: Ali Nekouzadeh, Jerome Olivas, Joshua Merilos, Matthew Wayne Janke, Justin Harris, Marc Orloff, Edward Stapleford Nielsen, Chitra Nadig, Yasaman Damestani, Guojie Song, Bryton De Guia
  • Publication number: 20190083703
    Abstract: Disclosed herein are self-degradable microneedle devices for the controlled-release of an immunotherapeutic agent. Also disclosed are methods for treating a disease (for example, cancer) using a self-degradable microneedle patch for the sustained delivery of an immunotherapeutic agent (for example, a PD1 antibody).
    Type: Application
    Filed: March 1, 2017
    Publication date: March 21, 2019
    Inventors: Zhen Gu, Chao Wang, Yanqi Ye
  • Publication number: 20190083704
    Abstract: A cannula insertion device is disclosed. The device includes a needle carriage, a rail device on which the needle carriage is slidable, a yoke having a channel, a linkage connected to the needle carriage and extending into the channel, a torsion spring with one end connected to the linkage, and locking device for locking the torsion spring in tension and maintaining the needle carriage and the linkage in a locked position prior to activation. Upon release of the locking device, the tension of the torsion spring is released, which causes the linkage to move in the channel and slide the needle carriage along the rail device. A catheter carriage may also be provided for actuation by the linkage.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Inventors: Russell COLE, Alyssa JACKSON
  • Publication number: 20190083705
    Abstract: A method of embolizing a tumor includes advancing a distal end of a device having a catheter body and an occlusion structure to a target tumor site within a blood vessel of a body. The occlusion structure is activated within the blood vessel, and a real time pressure measurement in the vascular space distal to the activated occlusion structure is monitored. The method further includes waiting for a pressure drop in the vascular space distal to the activated occlusion structure and for the pressure drop to cause a blood flow reversal in branch vessels antegrade to the occlusion. An embolic substance is injected from the distal end of the delivery device to permit the reversed blood flow to carry the embolic substance into the vasculature of the target tumor and the device is withdrawn from the body. Other catheter assemblies and methods of use are also disclosed.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Inventor: Michael P. ALLEN
  • Publication number: 20190083706
    Abstract: Disclosed is a valve drive unit that has first and second SMA wires that can be alternatively activated. The valve drive unit further includes a pivoting member pivotably arranged around a pivoting member axis, the pivoting member including a valve driver arranged at a distance from the pivoting member axis. The first and second SMA wires are coupled to the pivoting member such that an activation of the first SMA wire causes the pivoting member to pivot into a first direction and an activation of the second SMA wire causes the pivoting member to pivot into a second direction, the second direction being opposite to the first direction. The valve driver is configured to releasably engage a valve driver coupler of a valve unit, such that, in the engaged state, a pivoting of the pivoting member is transmitted to the valve driver coupler via the valve driver.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Inventors: Hans List, Stefan Pfalz, Niklaus Schneeberger, Pierre Jaquier, Peter Siegrist
  • Publication number: 20190083707
    Abstract: This pharmaceutical injection device may be provided with a main body case, a pharmaceutical syringe mounting portion, a piston, a piston feed screw or the like, and a cover. At a first end, the main body case may have an injection needle mounting portion to which an injection needle is mounted. The pharmaceutical syringe mounting portion may be provided inside the main body case, and a pharmaceutical syringe may be mounted thereto. The piston may be provided movably with respect to the pharmaceutical syringe that is mounted to the pharmaceutical syringe mounting portion. The piston feed screw or the like drives the piston. The cover may be provided on the first end side of the main body case and operates to open and close the injection needle mounting portion.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Applicant: PHC Holdings Corporation
    Inventors: Kenji MURAKAMI, Mitsuteru FUJIMOTO
  • Publication number: 20190083708
    Abstract: An electrical information device configured to communicate information related to a medicament delivery performed by a medicament delivery device is presented. The device includes at least one information communication unit configured to communicate the information, and at least one power providing arrangement including at least one power source, at least one electrical switch and at least one switch lock member. The at least one switch lock member being configured to be movable in an axial direction from a first position to a second position by an axial movement of at least one triggering member of the medicament delivery device, to cause a change of state of the at least one electrical switch in the second position, thereby providing electrical power to the at least one information communication unit from the at least one power source, and to be locked in the second position, such that the change of state of the electrical switch is maintained.
    Type: Application
    Filed: February 7, 2017
    Publication date: March 21, 2019
    Inventor: Daniel Säll
  • Publication number: 20190083709
    Abstract: A drug delivery device may include sterile needle covered by removable a sterility preserving protector. The device optionally includes skin contact surface and a needle protector for preventing a stick hazard upon removal of the skin contact surface from an injection site or angle without Removing completely. Optionally, the needle protector may include a shield that interferes with replacement of the needle protector. In some embodiments, the needle cover may interfere with deployment of the needle protector.
    Type: Application
    Filed: October 10, 2016
    Publication date: March 21, 2019
    Applicant: West Pharma. Services IL, Ltd.
    Inventors: Oz CABIRI, Ran HEZKIAHU
  • Publication number: 20190083710
    Abstract: A syringe assembly including a syringe barrel having a first end, a second end, and a sidewall extending therebetween defining a chamber is disclosed. The syringe assembly includes a stopper disposed within the chamber of the syringe barrel and a plunger rod having an inner member engaged with the stopper and an outer member adapted for telescopic movement with respect to the inner member. The plunger rod is transitionable from a collapsed position, in which a portion of the inner member is nested within the outer member, to an extended position, in which the same portion of the inner member extends outside the outer member. The syringe assembly also includes a stop member configured for cooperation with a portion of the syringe barrel, upon relative movement of the outer member with respect to the inner member, to limit the outward travel of the plunger rod from the syringe barrel.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 21, 2019
    Inventors: David Robert Schiff, Mathieu Dominic Turpault, Antonio Gatta, John Depler Coleman
  • Publication number: 20190083711
    Abstract: A plunging unit for a syringe is provided comprising (i) a plunger comprising a plunger head connected to a thumb rest by a shaft; and (ii) a pusher housing comprising a finger rest and an internal channel connecting a plunger-receiving end of the housing to a barrel-receiving end of the housing, wherein the plunger-receiving end is adapted to receive the plunger head into the channel and the barrel-receiving end comprises one or more protrusions adapted to engage a barrel of a carpule housing unit. The plunging unit optionally includes an aspirator adapted to cause a backward movement of the plunger away from a site of injection. The aspirator may comprise an actuator ring on the shaft of the plunger adjacent to the plunger-receiving end of the housing, and when the actuator ring is moved in a backward direction, a spring-loaded piston that sits within the pusher housing and houses the shaft of the plunger is pulled backward which causes the plunger to move backward.
    Type: Application
    Filed: September 20, 2018
    Publication date: March 21, 2019
    Inventors: Khurrum Masood Ashraf, Bruce Zagrodney
  • Publication number: 20190083712
    Abstract: Disclosed is an infusion device drive unit that includes a pump drive configured to operatively mechanically couple to a dosing unit to control operation of the dosing unit. The infusion device drive unit further includes a blocking member that is movable between a blocking configuration and a enabling configuration, the blocking member enabling the establishing and/or the releasing of an operative mechanical coupling between the pump drive and the dosing unit in the enabling configuration and preventing the establishing and/or the releasing of an operative mechanical coupling between the pump drive and the dosing unit in the blocking configuration. The infusion device drive unit controls the blocking member to take on the enabling configuration if the pump drive is in at least one pre-determined configuration and to take on the blocking configuration if the pump drive is in a configuration different from a pre-determined configuration.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Inventor: Hans List
  • Publication number: 20190083713
    Abstract: A drive mechanism of a drug delivery device and a respective drug delivery device for setting and dispensing of a dose of a medicament are presented, where the drive mechanism has an elongated housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge containing the medicament, a dosing arrangement manually and axially displaceable relative to the housing for setting and dispensing of the dose, and an accessory drive operably engaged with the piston rod to support a manually operated dose dispensing displacement of the dosing arrangement.
    Type: Application
    Filed: October 23, 2018
    Publication date: March 21, 2019
    Inventors: Paul Richard Draper, Anthony Paul Morris, Stephen Francis Gilmore
  • Publication number: 20190083714
    Abstract: An add-on device adapted to be releasably attached to a drug delivery device, the drug delivery device comprising an indicator adapted to display a dose amount during dose setting, and to display the remaining dose amount to be expelled during drug expelling. The add-on device comprises an electronically controlled display adapted to display a set dose amount, a sensor assembly adapted to detect movement of the dose setting member when the add-on device is attached to a drug delivery device, a camera device adapted to capture an image of the indicator, and processor means adapted to (i) control the display dynamically to show the set dose amount based on input from the sensor assembly, and (ii) determine an expelled dose amount based on input from the camera device.
    Type: Application
    Filed: February 27, 2017
    Publication date: March 21, 2019
    Inventor: Dan Groenkjaer Nielsen
  • Publication number: 20190083715
    Abstract: An electronic assembly includes a casing to conduct electricity flowing between at least some electronic components disposed within the casing. The electronic components include an ultrasonic transducer coupled to emit ultrasonic signals, and a battery to provide the electricity. A controller is coupled to the ultrasonic transducer and the battery, and the controller includes logic that when executed by the controller causes the electronic assembly to perform operations, including: instructing the first ultrasonic transducer to emit the ultrasonic signals.
    Type: Application
    Filed: September 20, 2018
    Publication date: March 21, 2019
    Inventors: John Redmond, Adam Reich
  • Publication number: 20190083716
    Abstract: A needle assembly for a medical device, comprising a needle hub adapted for receiving a needle cannula, and a needle shield having an open end. The needle assembly is adapted to be changed from an integral configuration, wherein the needle hub is aligned with the needle shield, wherein the first end of the needle shield is covered by the needle hub, and wherein a frangible connection forms an integral connection between a shield connecting portion and a hub connecting portion, to a broken configuration, wherein the frangible connection is broken, and whereby the needle hub and needle shield are two separate parts, and whereby the needle shield is removable from the needle hub.
    Type: Application
    Filed: October 7, 2016
    Publication date: March 21, 2019
    Applicant: Novo Nordisk A/S
    Inventor: Christian Saxe
  • Publication number: 20190083717
    Abstract: The invention generally relates to catheter systems and methods for guided formation of vascular access sites (such as fistulas and grafts). According to certain aspects, a catheter system for forming a vascular access site include an elongate body comprising a distal end and configured to be inserted into a first vessel. The elongate body includes an exit port along its side that is proximal to the distal end. An imaging assembly is associated with the elongate body and configured to generate image data of the first vessel and a second vessel positioned next to the first vessel. For vascular access formation, a penetrating member of the catheter system extends out of the exit port and through a wall of the first vessel and a wall of the second vessel.
    Type: Application
    Filed: November 9, 2018
    Publication date: March 21, 2019
    Inventors: Bradley S. MATSUBARA, John UNSER
  • Publication number: 20190083718
    Abstract: A magazine (18) that stores a plurality of needles (56) configured to engage a medication pen (2) for medication delivery, the magazine (18) comprising a magazine housing (20) enclosing a removable array (26) having a plurality of hub chambers (22) each enclosing one of a plurality of needle hubs (50), a connector (28) in each of the plurality of hub chambers (22), each connector (28) engages one of the plurality of needle hubs (50), a plurality of peel tabs (30) each sealing one of the plurality of hub chambers (22), and an electronic indicator (62) to identify a status of the plurality of needle hubs (50), wherein the electronic indicator (62) identifies how many of the plurality of needle hubs (50) are unused.
    Type: Application
    Filed: March 31, 2017
    Publication date: March 21, 2019
    Applicant: Becton, Dickinson and Company
    Inventors: Sudarsan Srinivasan, David Schiff, Stephan Lawson, Nicholas Hugh McGill
  • Publication number: 20190083719
    Abstract: A fragrance diffuser can include a reservoir adapted to hold a foundation liquid, a fragrance dock adapted to receive a container containing a fragrant liquid, a vaporizer adapted to atomize a liquid, the vaporizer configured to receive and vaporize at least a portion of the base liquid from the reservoir and at least a portion of the fragrant liquid from the container, a duct providing a fluid flow path between the vaporizer and an airspace that surrounds the fragrance diffuser and a discharge tray adapted to receive an unused portion of a liquid mixture comprising the base liquid and the fragrant liquid.
    Type: Application
    Filed: May 11, 2018
    Publication date: March 21, 2019
    Inventor: Jason P. Freeman
  • Publication number: 20190083720
    Abstract: A vapor provision apparatus including a vapor generation chamber containing a vaporizer for generating vapor from a vapor precursor material; and an air channel wall defining an air channel between the vapor generation chamber and a vapor outlet at a mouthpiece end of the vapor provision apparatus through which a user can inhale vapor during use; wherein an inner surface of the air channel wall is provided with at least one protrusion extending into the air channel to modify (redirect) a flow of air in the air channel during use. For example, the at least one protrusion may be arranged to define one or more portions of a helical wall extending into the air channel so as to impart a degree of rotation about an axis of extent of the air channel to air flowing in the air channel during use.
    Type: Application
    Filed: March 21, 2017
    Publication date: March 21, 2019
    Inventors: DAVID LEADLEY, JEREMY WRIGHT
  • Publication number: 20190083721
    Abstract: A high-flow luer lock connector is disclosed. A high-flow luer lock connector comprises a connector body defining an interior region, a lumen, and an extended passageway. The interior region is bounded by a cylindrical side wall and a base wall. The lumen is defined at the base wall of the interior region and extends no more than 0.274 of an inch into the interior region. The extended passageway comprises a first and second end and passes through the connector body and the lumen. The extended passageway is in communication with the interior region to allow insufflation gas to flow through the interior region and extended passageway.
    Type: Application
    Filed: August 27, 2018
    Publication date: March 21, 2019
    Applicant: Northgate Technologies
    Inventor: Robert R. Mantell
  • Publication number: 20190083722
    Abstract: A nasal delivery device for delivering substance to a nasal cavity of a subject comprises: a housing (15); a nosepiece (17) for fitting to a nasal cavity of the subject; a mouthpiece (19) through which the subject in use exhales; and a flexible coupling (20) which couples the mouthpiece to the housing, wherein the flexible coupling provides for asymmetric translation of the mouthpiece relative to the nosepiece.
    Type: Application
    Filed: August 14, 2018
    Publication date: March 21, 2019
    Inventors: Per Gisle DJUPESLAND, Joseph Gordon, Michael Leclerc, Ramy A. Mahmoud, Shane Siwinski
  • Publication number: 20190083723
    Abstract: Provided is a configuration capable of executing a detection test for a comfort level including the quality of sleep, which is measurable at home without requiring the measurement of brain waves or electrocardiogram. The respiratory waveform of a subject during sleep is continuously measured and recorded from the respiratory gas flow, etc., and is window-Fourier transformed at each measurement time to generate a frequency spectrum, and a bandwidth including a respiratory frequency is extracted. The index indicating the regularity of the respiratory period of the subject is also calculated at each time point during the sleep, and the time-dependency of this index during the sleep is represented as a graph. A medical device includes a sleep evaluation system equipped with a control means for performing control so that a sleep cycle repeated at a cycle of about 90 minutes is clearly observed if the comfort level including the quality of sleep of the subject is favorable.
    Type: Application
    Filed: September 18, 2018
    Publication date: March 21, 2019
    Applicants: Teijin Pharma Limited
    Inventor: Hidetsugu ASANOI
  • Publication number: 20190083724
    Abstract: The present invention concerns a pneumatic delivery device having three successively-arranged chambers, a membrane element arranged in the third chamber so as to ensure a tight separation of the third chamber into a lower chamber and upper chamber, a membrane element arranged between the second chamber and the lower chamber of the third chamber so as to ensure a tight separation between said lower chamber and second chamber, a stem integrally fixed to the first membrane element and to the second membrane element, a valve cooperating with an outlet orifice arranged between the first chamber and the second chamber, and a flow adjustment element arranged on a gas conduct in fluid communication with the gas outlet of the second chamber, said flow adjustment element being operable by a user for setting a quantity of gas circulating in said gas conduct.
    Type: Application
    Filed: August 23, 2018
    Publication date: March 21, 2019
    Inventor: Thierry BOULANGER
  • Publication number: 20190083725
    Abstract: There is provided system for monitoring spontaneous breathing of a mechanically ventilated target individual, comprising: a feeding tube for insertion into a distal end of an esophagus of the individual, sensor(s) disposed on the feeding tube at a location such that the sensor(s) is located at the distal end of the esophagus of the individual when the feeding tube is in use, wherein the sensor(s) is positioned for sensing values by contact with the tissue of the esophagus including a lower esophageal sphincter (LES) and/or tissue in proximity to the LES, and code for computing an indication of a frequency band of diaphragm movement of the individual according to an analysis of values sensed by the sensor(s), and for adjustment of parameter(s) of a mechanical ventilator for mechanically ventilating the individual, wherein the instructions for adjustment are computed while the feeding tube is in use.
    Type: Application
    Filed: June 6, 2018
    Publication date: March 21, 2019
    Inventors: Liron ELIA, Gavriel J. IDDAN
  • Publication number: 20190083726
    Abstract: A process for operating a ventilator (12) and a ventilator (12) operating according to the process are provided. A pressure target value (pz) is determined during a phase of exhalation (48) as a function of a compliance (C) determined in relation to the lungs (14) of a patient being ventilated by means of the ventilator (12).
    Type: Application
    Filed: September 19, 2018
    Publication date: March 21, 2019
    Inventors: Hans-Ullrich HANSMANN, Karsten HILTAWSKY
  • Publication number: 20190083727
    Abstract: A removable fiberoptic adapter is secured onto a respiratory-device, such as a laryngeal mask airway (LMA) or a ventilating airway mask, to allow for endoscopes to be inserted through the LMA while maintaining a connection to an oxygen source to sustain the patient as the patient breathes. The removable fiberoptic adapter includes an airway tube, an oxygen port, a carbon dioxide outlet, an implement port, and an adapter plug. The oxygen port and the carbon dioxide outlet allow for the introduction of air or oxygen and the removal of carbon dioxide for respiration of the patient. The oxygen port and the carbon dioxide outlet are laterally connected to the airway tube. The implement port allows for the insertion of endoscopes or other medical implements through the respiratory-device. The adapter plug engages the implement inlet in order to restrict fluid flow through the implement inlet.
    Type: Application
    Filed: July 24, 2018
    Publication date: March 21, 2019
    Inventors: Elena Anigati, Carol Anigati
  • Publication number: 20190083728
    Abstract: An airway management device (10) for a human or animal subject (20) includes an airway tube (101) having a first end for disposal external to the subject (20) and a second end (102) for disposal in a portion of an airway of the subject (20). A light emitting element (108) and a photo-sensing element (109) may be disposed at the second end (102) of the airway tube (101). The light emitting element (108) may be configured to transmit light to tissue adjacent to the light emitting element (108). The photo-sensing element (109) may be configured to receive reflectance spectra (204) from the tissue. The location of the second end (102) of the airway tube (101) may be determined from characteristics of the reflectance spectra (204) of the tissue.
    Type: Application
    Filed: August 1, 2018
    Publication date: March 21, 2019
    Applicant: THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY
    Inventors: Corinne NAWN, Brian SOUHAN
  • Publication number: 20190083729
    Abstract: A tracheal tube assembly includes an outer cannula configured to be positioned in a patient airway and an inner cannula configured to be disposed inside the outer cannula. The tracheal tube assembly further includes a flange member secured about the outer cannula, and an outer cannula connector coupled to a proximal end of the outer cannula. The inner cannula includes a compressible proximal end region that is compressed while secured inside the outer cannula connector.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 21, 2019
    Inventors: Martin Bruggeman, James Michael Ryan, Declan Kiernan, Alan Finneran
  • Publication number: 20190083730
    Abstract: A laryngeal mask is provided which has a mask body having a capsule body and a support body, wherein a groove is provided on the top of the support body, and the capsule body is correspondingly disposed on the groove; and a tube body having an airway tube body, wherein one end of the tube body is bonded to the support body, and the bonding portion is provided with an opening communicating with one end of the airway tube body.
    Type: Application
    Filed: September 19, 2018
    Publication date: March 21, 2019
    Applicant: E-PROSPERITY & DEVELOPMENT CO., Ltd.
    Inventors: CHEN-CHUN LIAO, JIUN-YI LI, CHENG-SHIH LIEN