Patents Issued in March 21, 2019
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Publication number: 20190083781Abstract: Embodiments provide systems for delivering cosmetic agents (CA) into the skin. The system includes a power source and at least two electrode assemblies (EA) which may be attached or otherwise incorporated into a facemask assembly that fits over the user's face. Each EA is configured to be held in contact with a facial or other skin layer. Additionally, each EA includes an electrode that is coupled to the power source to receive an output current from the power source. At least one of the EAs in the pair includes a medium that carries a CA, the medium being provided on the at least one electrode assembly to enable the output current to deliver the cosmetic agent into the epidermal dermal or other layer of the skin. Embodiments are particularly useful for delivering CAs into a selected layer of the skin to produce a desired cosmetic effect.Type: ApplicationFiled: September 18, 2018Publication date: March 21, 2019Inventor: Mir A. Imran
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Publication number: 20190083782Abstract: Embodiments provide systems for delivering cosmetic agents (CA) into the skin. The system includes a power source and at least two electrode assemblies (EA) which may be attached or otherwise incorporated into a facemask assembly that fits over the user's face. Each EA is configured to be held in contact with a facial or other skin layer. Additionally, each EA includes an electrode that is coupled to the power source to receive an output current from the power source. At least one of the EAs in the pair includes a medium that carries a CA, the medium being provided on the at least one electrode assembly to enable the output current to deliver the cosmetic agent into the epidermal dermal or other layer of the skin. Embodiments are particularly useful for delivering CAs into a selected layer of the skin to produce a desired cosmetic effect.Type: ApplicationFiled: September 18, 2018Publication date: March 21, 2019Inventor: Mir A. Imran
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Publication number: 20190083783Abstract: Some embodiments relate to a method of treating a waste evacuation dysfunction, comprising administering transcutaneous electrical stimulation (TES) to at least one lower pelvic and/or sacral region for at least one treatment period per day over a treatment term of at least one week.Type: ApplicationFiled: September 13, 2018Publication date: March 21, 2019Inventors: Bridget Rae Southwell, John Medwyn Hutson, Andre Yi Feng Tan
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Publication number: 20190083784Abstract: Restless Leg Syndrome (RLS) or Periodic Limb Movement Disorder (PLMD) can be treated using high frequency (HF) electrostimulation. This can include selecting or receiving a subject presenting with RLS or PLMD. At least one electrostimulation electrode can be located at a location associated with at least one of, or at least one branch of, a sural nerve, a peroneal nerve, or a femoral nerve. HF electrostimulation can be delivered to the subject, which can include delivering subsensory, subthreshold, AC electrostimulation at a frequency that exceeds 500 Hz and is less than 15,000 Hz to the location to help reduce or alleviate the one or more symptoms associated with RLS or PLMD. A charge-balanced controlled-current HF electrostimulation waveform can be used.Type: ApplicationFiled: November 20, 2018Publication date: March 21, 2019Inventor: Shriram Raghunathan
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Publication number: 20190083785Abstract: A device and method is provided for stimulation of neurons. The device includes a stimulation unit that can be implanted into a body of a patient and has stimulation elements that apply a stimulation signal to tissue of the patient to stimulate neurons in the brain and/or the spinal cord of the patient. Moreover, a measuring unit receive a measurement signal that reflects a neuronal activity of the stimulated neurons. Further, a control unit generate a modulation signal from the measurement signal, and modulates an amplitude of a pulse train with the modulation signal. Individual pulses of the pulse train include a first and second pulse portions that introduce and remove charge from the tissue. Moreover, the control unit varies a pause between the pulse portions until the synchronization of the stimulated neurons is minimized or falls below a predetermined threshold.Type: ApplicationFiled: March 14, 2017Publication date: March 21, 2019Applicant: Forschungszentrum Juelich GmbHInventors: Peter Alexander TASS, Oleksandr POPOVYCH
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Publication number: 20190083786Abstract: A medical device detects a previously defined event, and controls delivery of therapy to a patient according to therapy information associated with the previously defined event. In exemplary embodiments, the medical device enters a learning mode in response to a command received from a user, e.g., the patient or a clinician. In such embodiments, the medical device defines the event, collects the therapy information, and associates the therapy information with the defined event while operating in the learning mode. In some embodiments, the medical device defines the event based on the output of a sensor that indicates a physiological parameter of the patient during the learning mode. The sensor may be an accelerometer, which generates an output that reflects motion and/or posture of the patient. The medical device may collect therapy information by recording therapy changes made by the user during the learning mode.Type: ApplicationFiled: November 9, 2018Publication date: March 21, 2019Inventors: Ruchika Singhal, Steven L. Jensen, Robert M. Skime
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Publication number: 20190083787Abstract: An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a plurality of electrically isolated electrodes called passive electrodes or field-shaping electrodes that are located under the surface of the supporting structure. The passive electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Passive or field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field in the space surrounding the electrodes, which has consequence on the path of the stimulating currents injected by other devices or by the organism itself. The invention also discloses locating the passive electrodes on surfaces that surround the desired target volume.Type: ApplicationFiled: October 31, 2018Publication date: March 21, 2019Inventor: Sergio Lara Pereira Monteiro
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Publication number: 20190083788Abstract: An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a plurality of electrically isolated electrodes called passive electrodes or field-shaping electrodes that are located under the surface of the supporting structure. The passive electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Passive or field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field in the space surrounding the electrodes, which has consequence on the path of the stimulating currents injected by other devices or by the organism itself. The invention also discloses locating the passive electrodes at different depths from the surface of the supporting structure.Type: ApplicationFiled: October 31, 2018Publication date: March 21, 2019Inventors: Daisong Zhang, Sergio Lara Pereira Monteiro
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Publication number: 20190083789Abstract: Systems and methods for managing heart failure are described. The system receives physiological information including a first HS signal corresponding to paced ventricular contractions and a second HS signal corresponding to intrinsic ventricular contractions. The system detects worsening heart failure (WHF) using the received physiological information. A signal analyzer circuit can generate a paced HS metric from the first HS signal and a sensed HS metric from the second HS signal, and determine a concordance indicator between the paced and the sensed HS metrics. In response to the detected WHF, the system can use the concordance indicator to generate a therapy adjustment indicator for adjusting electrostimulation therapy, or a worsening cardiac contractility indicator indicating the detected WHF is attributed to degrading myocardial contractility.Type: ApplicationFiled: August 28, 2018Publication date: March 21, 2019Inventors: Pramodsingh Hirasingh Thakur, Jason Humphrey, David J. Ternes, Qi An, Krzysztof Z. Siejko, Michael James Dufresne, Yinghong Yu
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Publication number: 20190083790Abstract: A medical device is configured to deliver a high-energy electrical stimulation pulse to a patient that produces a post-stimulation polarization signal. A cardiac signal analyzer of the medical device is configured to detect a cardiac electrical signal superimposed on the post-stimulation polarization signal, determine at least one feature of the detected cardiac electrical signal, compare the feature to criteria that differentiate an intrinsic cardiac event during the post-stimulation polarization signal from an evoked response signal and identify the detected cardiac electrical signal as the intrinsic cardiac event if the feature meets the criteria.Type: ApplicationFiled: November 20, 2018Publication date: March 21, 2019Inventors: Saul E. GREENHUT, Michael T. HEMMING
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Publication number: 20190083791Abstract: Systems, methods, and devices for determining occurrences of a tamponade condition are disclosed. One exemplary method includes monitoring an accelerometer signal of a leadless cardiac pacemaker attached to a heart wall, determining if a tamponade condition of the patient's heart is indicated based at least in part on the monitored accelerometer signal, and in response to determining that the tamponade condition is indicated, providing a notification of the tamponade condition for use by a physician to take corrective action.Type: ApplicationFiled: November 15, 2018Publication date: March 21, 2019Applicant: Cardiac Pacemakers, Inc.Inventors: Michael J. Kane, Allan Charles Shuros, Brian L. Schmidt, Keith R. Maile, Benjamin J. Haasl
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Publication number: 20190083792Abstract: The present disclosure relates to an implantable lead comprising an elongated lead body having at least one lumen therein and at least one through hole, and at least one electrically conductive wire. For at least one of said at least one lumen, a first through hole extends from an outer surface of the lead body into said lumen, and an electrically conductive wire is arranged in said lumen at least on one side of said first through hole. Furthermore, said electrically conductive wire is further arranged in a configuration exiting the lumen via said first through hole and wound around a predefined portion of the outer surface of the lead body.Type: ApplicationFiled: September 13, 2018Publication date: March 21, 2019Inventor: Jean-Francois Ollivier
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Publication number: 20190083793Abstract: An operating-room cable-assembly for an electrical-stimulation system includes a lead connector with a lead passageway defined in a housing. Contacts disposed in the housing engage terminals of a lead when the lead is operationally-inserted into the lead passageway. A first biased tab is disposed in a first tab lumen defined in the housing. The first biased tab has a first end exposed to an outer surface of the housing and an opposing second end exposed to the lead passageway. The first biased tab moves to an unlock position and is biased to return to a lock position. When in the lock position, the first biased tab is biased to exert a force against an inserted lead sufficient to resist axial movement of the lead relative to the lead connector.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Inventor: Ranjan Krishna Mukhari Nageri
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Publication number: 20190083794Abstract: An operating room cable assembly for an electrical stimulation system that includes a lead connector having a housing, a lead lumen extending inwardly from a first opening in the housing and configured and arranged to receive a portion of a lead or lead extension, and a contact assembly disposed within the housing and configured and arranged to move relative to the housing. The contact assembly is configured and arranged to move to a load position and is biased to return to a lock position. The contact assembly includes of contacts that are configured and arranged to engage a portion of any lead or lead extension within the lead lumen when the contact assembly is in the lock position and to disengage from the portion of the lead or lead extension within the lead lumen when the contact assembly is in the load position.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Inventor: Ranjan Krishna Mukhari Nageri
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Publication number: 20190083795Abstract: The present disclosure relates to an electrical connector cap, in particular for an implantable lead, the electrical connector cap comprising an elongated body having at least one lumen and at least one through hole extending from an outer surface of the elongated body into the lumen, and at least one electrically conductive member arranged on an outer circumference of the elongated body over said at least one through hole of the elongated body. Furthermore, said at least one electrically conductive member comprises at least one through hole (extending from an outer surface of the electrically conductive member into the lumen through said at least one through hole of the elongated body. The disclosure further relates to implantable lead assemblies comprising said electrical connector cap, and to an implantable lead member usable with said electrical connector cap.Type: ApplicationFiled: September 19, 2018Publication date: March 21, 2019Inventor: Jean-Francois Ollivier
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Publication number: 20190083796Abstract: An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Inventors: Pujitha Weerakoon, David M. Wagenbach, Philip L. Weiss, Goran N. Marnfeldt
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Publication number: 20190083797Abstract: An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.Type: ApplicationFiled: September 14, 2018Publication date: March 21, 2019Inventors: Pujitha Weerakoon, David M. Wagenbach, Philip L. Weiss, Goran N. Marnfeldt, Kiran K. Gururaj
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Publication number: 20190083798Abstract: Methods and devices for providing noninvasive electrotherapy and electrical stimulation are described herein. In one aspect, a device for noninvasive electrotherapy includes wireless communication circuitry configured to receive pulse generation control signals wirelessly transmitted from a computing device. The device can include pulse generation circuitry configured to deliver electrical waveforms according to instructions encoded in the pulse generation control signals. The computing device can include a cellular telephone device, a portable media player, a personal digital assistant, a tablet computer, or an internet access device.Type: ApplicationFiled: September 10, 2018Publication date: March 21, 2019Inventors: Thomas Jerome Bachinski, Michael Wayne Moore, Joseph Winn, Jay Dave, David Orr, Dain Silvola
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Publication number: 20190083799Abstract: An adapter includes a first connector, a second connector, and a circuit that reverses a polarity of a signal received at the first connector. Moreover, a lead includes a connector including a cathode terminal and an anode terminal, an electrode including a tip and a ring, and a circuit that connects the anode terminal of the connector to the tip of the electrode and that connects the cathode terminal of the connector to the ring of the electrode.Type: ApplicationFiled: July 18, 2018Publication date: March 21, 2019Inventor: Morton M. MOWER
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Publication number: 20190083800Abstract: A pacemaker has a housing and a therapy delivery circuit enclosed by the housing for generating pacing pulses for delivery to a patient's heart. An electrically insulative distal member is coupled directly to the housing and at least one non-tissue piercing cathode electrode is coupled directly to the insulative distal member. A tissue piercing electrode extends away from the housing.Type: ApplicationFiled: September 13, 2018Publication date: March 21, 2019Inventors: Zhongping YANG, Becky L. DOLAN, Xin CHEN, Thomas A. ANDERSON, Berthold STEGEMANN, Gerard Johannes Jozef BOINK, Maurice VERBEEK
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Publication number: 20190083801Abstract: An implantable medical device has a housing having a proximal end, a distal end and an outer sidewall extending from the proximal end to the distal end. A fixation sheath includes a housing sheath portion extending along the outer sidewall of the housing, and a fixation member portion extending from the housing sheath portion. The housing sheath portion is advanceable from a first position along the outer sidewall of the housing in which the fixation member portion is retracted toward the proximal end of the housing to a second position along the outer sidewall of the housing in which the fixation member portion is deployed to extend away from the housing distal end for anchoring the implantable medical device at an implant site.Type: ApplicationFiled: September 15, 2017Publication date: March 21, 2019Inventors: Zhongping YANG, Thomas A. ANDERSON, Yong K. CHO, Becky L. DOLAN, Rick D. MCVENES
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Publication number: 20190083802Abstract: An implantable cardiac device that detects and protects against strong magnetic fields produced by MRI equipment is disclosed. The device has a magnetic field sensor for detecting the presence of a relatively weak static magnetic field (102, 110, 118, 122) of a level equivalent to that of a permanent magnet in the vicinity of the device. The device is switched from a standard operating mode (100) where the nominal functions of the device are active, to a specific protected MRI mode (114, 116) in the presence of a magnetic static field of a level corresponding to that emitted by MRI equipment. The device further temporarily switches the device from the standard operating mode (100) to an MRI stand-by state (108) when a magnetic field is detected by the magnetic field sensor such that a subsequent detection of a magnetic field switches the device from an MRI stand-by state to the specific protected MRI mode.Type: ApplicationFiled: November 16, 2018Publication date: March 21, 2019Applicant: SORIN CRM SASInventors: Thierry Legay, Dominique Decoene
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Publication number: 20190083803Abstract: The current technology relates to a shock deferral unit that is portable by an ambulatory patient. The shock deferral unit has a bi-directional communication device configured to receive a notification of an impending shock from a defibrillator and configured to send an instruction to defer the impending shock to the defibrillator. An authentication interface is configured to receive authentication data from a user. A user instruction interface is configured to receive the instruction to defer the impending shock from the user. An authentication device is configured to authenticate the user based on the authentication data and instruct the bi-directional communication device to send the instruction to defer a shock upon authentication and receipt of the instruction to defer the shock.Type: ApplicationFiled: November 15, 2018Publication date: March 21, 2019Inventors: Jeffrey E. Stahmann, Dan C. Goldman
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Publication number: 20190083804Abstract: An implantable cardioverter defibrillator (ICD) receives a cardiac electrical signal by a sensing circuit while operating in a sensing without pacing mode and detects asystole based on the cardiac electrical signal. The ICD determines, in response to detecting the asystole, if asystole backup pacing is enabled, and automatically switches to a temporary pacing mode in response to the asystole backup pacing being enabled. Other examples of detecting asystole and providing a response to detecting asystole by the ICD are described herein.Type: ApplicationFiled: November 19, 2018Publication date: March 21, 2019Inventors: Yanina GRINBERG, Robert T. SAWCHUK, Amy E. THOMPSON-NAUMAN, Douglas A. PETERSON, Paul R. SOLHEIM, Joel R. LAUER
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Publication number: 20190083805Abstract: The disclosures provided herewith relate to diagnosis and treatment of post-traumatic stres disorder (PTSD).Type: ApplicationFiled: March 23, 2017Publication date: March 21, 2019Inventor: Amit Etkin
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Publication number: 20190083806Abstract: An optical treatment apparatus includes: a power source unit; a light irradiation module, that irradiates an affected part with light; a spacer that is positioned between the light irradiation module and the affected part; a fixing material that applies pressure to the light irradiation module and fixes the light irradiation module at an installation position; and a shielding material that covers the light irradiation module, in which, in a case where the pressure applied by the fixing material becomes lower than predetermined pressure, supply of current is stopped.Type: ApplicationFiled: May 19, 2017Publication date: March 21, 2019Applicant: SHARP KABUSHIKI KAISHAInventors: KATSUJI IGUCHI, HIROYA SATO, TAKASHI YOSHIMOTO, JUN MORI
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Publication number: 20190083807Abstract: Differing from conventional approaches for improving sexual dysfunction of an adult man being commonly carried out by letting the adult man administer a dosage of synthetic drug or a composition of Chinese herbal medicines, the present invention particularly discloses a method for treating male sexual dysfunction by using underpants comprising far-infrared fibers. A variety of clinical data have proved that, after wearing this underpants for 3 months, both the men diagnosed with sexual dysfunction and the men not sure to suffer from sexual dysfunction have an apparent progress on improvements of their erectile ability, erectile quality, ejaculation control ability, and lower urinary tract symptoms (LUTS). Moreover, clinical data have also proved that, despite the fact that a male person wears the underpants provided by the present invention for three months, there is no adverse effect induced by the underpants for causing the physiological condition of the men be abnormal.Type: ApplicationFiled: September 20, 2017Publication date: March 21, 2019Inventor: Tien-Show Liang
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Publication number: 20190083808Abstract: An apparatus is provided. The apparatus includes a flexible wrap and a plurality of lights arranged on the wrap. The wrap is configured to wrap around a body of a user such that the lights face selected areas of the body. The apparatus is configured to cause the lights to emit light at a first predetermined wavelength to the selected areas of the body that is sufficient to perforate one or more fat cells at the selected areas of the body to drain the content within the one or more fat cells when power is supplied to the lights. The apparatus is configured to cause the lights to emit light at a second predetermined wavelength to the selected areas of the body at the same time as the lights emit light at the first predetermined wavelength when power is supplied to the lights.Type: ApplicationFiled: September 20, 2017Publication date: March 21, 2019Inventor: Jessica Iverson
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Publication number: 20190083809Abstract: The invention comprises componentry and devices for light therapy application to a patient in need thereof. The present invention relates to controllers for light therapy devices, light delivery elements, light guides, light guide arrangements configured to deliver personalized light therapy to one or more patients, with related componentry, dosage, and configurations of light therapy delivery elements (e.g., bandages, garments, braces, inserts etc.) suitable to deliver light therapy to one or more patient body areas and associated tissues, as well as sensors for monitoring treatment progress and dosage optimization. Methods of delivering light therapy to a patient and treatment of associated medical indications are also set out herein. Personalized LLLT dosage configurations and telemedicine LLLT treatment platforms and systems are also provided herein.Type: ApplicationFiled: August 23, 2018Publication date: March 21, 2019Inventor: Jack K. Zhang
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Publication number: 20190083810Abstract: A system for treating a region of the epidermis, including: at least one laser energy source; a time control device to generate a laser beam; a laser energy focusing system arranged and produced to direct a laser beam on the region of the epidermis. The control device generates a laser beam including a plurality of composite pulses, emitted at a base frequency, each composite pulse including a sequence of sub-pulses at a higher frequency than the base frequency.Type: ApplicationFiled: November 15, 2018Publication date: March 21, 2019Inventors: Stefano MODI, Maurizio SCORTECCI, Damiano FORTUNA, Tiziano ZINGONI, Leonardo MASOTTI, Gabriele CLEMENTI, Nicola ZERBINATI
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Publication number: 20190083811Abstract: According to some aspects, a carrier configured for use with a broadband x-ray source comprising an electron source and a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target is provided. The carrier comprising a housing configured to be removably coupled to the broadband x-ray source and configured to accommodate a secondary target capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation, the housing comprising a transmissive portion configured to allow broadband x-ray radiation to be transmitted to the secondary target when present, and a blocking portion configured to absorb broadband x-ray radiation.Type: ApplicationFiled: November 6, 2018Publication date: March 21, 2019Applicant: Imagine Scientific, Inc.Inventor: Eric H. Silver
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Publication number: 20190083812Abstract: The invention relates to a determination apparatus for determining the pose and shape of an introduction element like a catheter within a living being, wherein the introduction element (12) is adapted to be used by a brachytherapy apparatus for introducing a radiation source (10) close to a target object (11) to be treated. A position determination element (27) like guidewire (20) with an electromagnetic tracking element (16) is introduced into the introduction element (12) such that it is arranged at different locations within the introduction element (12), wherein the positions of the position determination element (27) within the introduction element (12) are determined. The determined positions are then acquired depending on the determined positions for determining the pose and shape of the introduction element within the living being. This can lead to a determination procedure with reduced user interaction, thereby simplifying the determination procedure for the user.Type: ApplicationFiled: November 14, 2018Publication date: March 21, 2019Inventors: Shyam BHARAT, Ehsan Dehghan Marvast, Jochen Kruecker, Cynthia Ming-fu Kung
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Publication number: 20190083813Abstract: Generally speaking, pursuant to these various embodiments a memory stores prescribed treatment instructions for a particular patient radiation therapy. Those treatment instructions specify clinical metrics for goals pertaining to at least one treatment volume for the particular patient. Either directly or inferentially those clinical metrics are prioritized. A control circuit automatically converts those treatment instructions into resultant radiation treatment plan optimization objectives where the automatic conversion can compatibly comprise a non-convex optimization objective. The control circuit then automatically iteratively optimizes the radiation treatment plan for the particular patient radiation therapy as a function, at least in part, of the aforementioned resultant optimization objectives to thereby produce an optimized radiation treatment plan for the particular patient that a radiation treatment platform then utilizes to administer therapeutic radiation to the particular patient.Type: ApplicationFiled: September 15, 2017Publication date: March 21, 2019Inventors: Emmi Ruokokoski, Jarkko Y. Peltola, Esa Kuusela
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Publication number: 20190083814Abstract: Computer-implemented methods and systems can be used to facilitate generation of VMAT treatment plans for providing radiation therapy to patients. Starting from a seed plan, a library of alternative plans, each with an associated outcome for a set of treatment objectives, can be generated via a set of parallel optimization operations performed on the seed plan. A graphical user interface is provided, via which the user can navigate within a treatment space defined by the alternative plans to identify a satisfactory outcome. Based on the satisfactory outcome and a candidate plan selected from the alternative plans, a deliverable VMAT treatment plan can be generated using another optimization operation.Type: ApplicationFiled: September 21, 2017Publication date: March 21, 2019Inventors: Tuomas Tallinen, Stephen K. Thompson, Joona Hartman, Perttu Niemelä
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Publication number: 20190083815Abstract: Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.Type: ApplicationFiled: November 16, 2018Publication date: March 21, 2019Inventors: Samuel MAZIN, Akshay NANDURI
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Publication number: 20190083816Abstract: A sensing device for a radiation therapy apparatus, the apparatus comprising an accelerator and a beam-shaping device the beam shaping device being a multi-leaf collimator (MLC) (2) having a plurality of pairs of leaves, and a rotatable gantry, the sensing device comprising: a transmission electronic detector (1) comprising an array of ionization chambers. The ionization chambers are defined by a bias electrode (11a,11b, 34,42) on the one hand and by a planar array of conductive strips (40) or strip assemblies (30) on the other hand. The strips or strip assemblies are associated to the leaf pairs of the MLC. The strips are the collecting electrodes of the ionization chambers.Type: ApplicationFiled: September 20, 2018Publication date: March 21, 2019Applicant: Ion Beam Applications S.A.Inventors: David MENICHELLI, Lutz MÜLLER, Jochen KRIMMER
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Publication number: 20190083817Abstract: Disclosed are methods, systems, and non-transitory computer readable media having stored thereon executable instructions that when executed by the processor of a computer control the computer to perform therapeutic ultrasound, such for the treatment of Ischemic reperfusion injury (IRI). The methods, systems, and non-transitory computer readable media can involve steps comprising: imaging a target tissue region within said subject, such as wherein the target tissue region comprises spleen tissue; identifying a volume region of interest (ROI) in said target tissue; and applying ultrasonic energy to the ROI, wherein applying the ultrasonic energy comprises emitting a sequence of ultrasonic pulses from an ultrasound transducer, the sequence of ultrasound pulses having predetermined frequency, mechanical index, pulse lengths, and pulse spacings, while performing a volumetric sweep through the ROI systematically for a selected total time duration, such as between about 3 minutes and about 15 minutes.Type: ApplicationFiled: May 3, 2017Publication date: March 21, 2019Inventors: Mark D. Okusa, Joseph C. Gigliotti, John A. Hossack
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Publication number: 20190083818Abstract: Various devices related to a therapeutic ultrasound device for use during a medical procedure to cauterize tissue are disclosed. The therapeutic ultrasound device can include an inner tube assembly and an outer tube assembly. The device can further include a tissue engagement assembly that is secured to the distal end of the inner tube and the distal end of the outer tube. The tissue engagement assembly includes a plurality of transducers configured to provide therapeutic ultrasound. The device can include a housing assembly that is secured to the proximal end of the inner tube and the proximal end of the outer tube. The housing assembly can include a handle configured to actuate the inner tube relative to the outer tube to engage and disengage the tissue engagement assembly.Type: ApplicationFiled: October 18, 2017Publication date: March 21, 2019Inventors: Stuart B. Mitchell, Eric Hadford, Daniel Baker
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Publication number: 20190083819Abstract: Various devices related to a therapeutic ultrasound device for use during a medical procedure to cauterize tissue are disclosed. The high intensity focused ultrasound device can include a transducer for producing high intensity focused ultrasound. The transducer includes a shell configured to receive an acoustic stack. The acoustic stack includes a piezoelectric layer, a matching layer, and a plurality of electrodes. The transducer includes an air-filled pocket formed between the inner surface of the shell and the piezoelectric layer of the acoustic stack, wherein the air-filled pocket is configured to ensure high efficiency of the transducer.Type: ApplicationFiled: October 18, 2017Publication date: March 21, 2019Inventors: Stuart B. Mitchell, Eric Hadford, Daniel Baker
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Publication number: 20190083820Abstract: Ambrisentan and formulations thereof for use in the treatment and prevention of acute renal failure associated with renal vasoconstriction.Type: ApplicationFiled: March 20, 2017Publication date: March 21, 2019Applicant: Noorik Biopharmaceuticals AGInventors: Iker NAVARRO, Satish KHANNA
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Publication number: 20190083821Abstract: A method is for operating an electromechanical or electrohydraulic work appliance or rescue appliance that can be carried and used by an operator, having a movable tool insert, a spreading tool or a lifting tool, a housing, an electric motor, a pump or a mechanical transmission driven by the electric motor, for actuating the tool insert. The appliance has an exchangeable, rechargeable appliance electrical energy source, having a housing in or on the rescue appliance. During operation of the appliance, operating data of the appliance and/or of the energy source are acquired and transferred into a data carrier or data storage device in the electrical energy source. The electrical energy source is removed from the appliance and connected to a charging device. The operating data stored in the data carrier or storage device of the electrical energy source are read by the charging device and transferred to a network.Type: ApplicationFiled: May 6, 2016Publication date: March 21, 2019Applicant: LUKAS Hydraulik GmbHInventors: Carsten SAUERBIER, Tammy HORNE, Ian CUBA, William J. BROWN, Nick RAMIREZ, Uwe KIRCHNER
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Publication number: 20190083822Abstract: A respirator has a shell that defines a breathable air zone for a user wearing the respirator. An air flow control system for the respirator has an air delivery conduit within the shell of the respirator, a valve member moveable relative to the air delivery conduit and within the shell to vary the amount of air flow through the air delivery conduit, and a valve actuator outside of the shell of the respirator. The valve actuator is manipulatable by a user of the respirator while wearing the respirator to control movement of the valve member.Type: ApplicationFiled: October 23, 2018Publication date: March 21, 2019Inventors: Garry J. Walker, Andrew Murphy, Desmond T. Curran, Derek A. Parkin, Thomas I. Insley, Mark A.J. Fernandes
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Publication number: 20190083823Abstract: The present disclosure provides a respiratory protection device that includes a valve assembly operable between an open configuration and a closed configuration. In some exemplary embodiments, the respiratory protection device includes a mask body having a first air chamber, a second air chamber, and a breathable air zone. A valve assembly is operable to a closed configuration to prevent airflow from the first and second air chambers into the breathable air zone.Type: ApplicationFiled: March 15, 2017Publication date: March 21, 2019Inventor: David M. Castiglione
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Publication number: 20190083824Abstract: A preferred embodiment suspension trauma relief strap assembly for use with a full body harness includes a pair of straps connectable in two configurations. The first configuration is formed by engaging a hook of one strap with one of a plurality of closed loop arrangements of the other strap to form a sling upon which a person donning the full body harness may stand. The second configuration is formed by engaging the hook of the one strap with one of the plurality of closed loop arrangements of the one strap and engaging the hook of the other strap with one of the plurality of closed loop arrangements of the other strap to form two slings upon which a person donning the full body harness may stand.Type: ApplicationFiled: November 15, 2018Publication date: March 21, 2019Inventors: J. Thomas Wolner, Travis P. Betcher
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Publication number: 20190083825Abstract: A weight bearing fall protection connector includes a first connection member configured to attach the connector to a piece of fall protection equipment, and a second connection member configured to attach the connector to another piece of all equipment, with the connection members fixed to each other to transfer the weight of a worker in a fall event and for movement relative to each other between a ready position and a fall position. The connector further includes a breakable component having a retaining condition wherein the component maintains the members in a ready position and broken condition wherein the component allows the members to move to their fall position. The connector further includes a wireless fall indicator including a wireless transmitter and a switch configured to activate the wireless transmitter in response to movement of the members from the ready position to the fall position.Type: ApplicationFiled: April 14, 2016Publication date: March 21, 2019Inventors: Steve Huseth, Bradley Rohlf, Michael Fegley, Steven Joseph Sharp, Cinnamon C. Deets, William A. Zachar, JR.
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Publication number: 20190083826Abstract: A fall protection device includes a frame, a rotation unit, a safety belt, a braking plate, a braking block and a restoring spring. The frame includes a first lateral plate, and a stopping block is formed on an exterior surface of the first lateral plate. The rotation unit is rotatably disposed with the frame. The safety belt is wound around the rotation unit. The braking plate is engaged with the rotation unit and includes an interior surface which faces the exterior surface of the first lateral plate. The braking block is pivotally disposed on the braking plate and located between the interior surface of the braking plate and the exterior surface of the first lateral plate. The present invention could ensure the braking block to abut against the stopping block as the braking block is at an expanding position, and thereby to improve a reliability of the lockup function.Type: ApplicationFiled: January 17, 2018Publication date: March 21, 2019Applicant: YOKE INDUSTRIAL CORP.Inventor: EASON SUN
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Publication number: 20190083827Abstract: A fall protection device includes a frame, a rolling member, a safety belt, a braking plate, a braking part, and a restoring spring. The frame has a first side plate. An outer side surface of the first side plate is provided with a blocking part. A rolling member is rotatably disposed on the frame. A safety belt is wound around the rolling member. A braking plate is engaged to the rolling member and has an inner side surface, which faces the outer side surface. The braking part is pivotally disposed on the braking plate and is located between the inner side surface and the outer side surface, whereby to ensure that the braking part at a braking position could be abutting against the blocking part.Type: ApplicationFiled: September 19, 2018Publication date: March 21, 2019Applicant: YOKE INDUSTRIAL CORP.Inventors: Wei-Chieh HUNG, Jyu-Yi WANG, Eason SUN
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Publication number: 20190083828Abstract: A fall arrest device includes a bracket having a first and second side panels, a rotating member rotatably mounted to the bracket, a safety belt wound around the rotating member, a brake wheel engaged with the rotating member and having a groove, a brake block pivotally connected to the brake wheel and located between an inner surface of the brake wheel and an outer surface of the first side panel, and a restoring spring. A stopper is disposed on the outer surface of the first side panel. In this way, the groove could accommodate a part of a body of the restoring spring, preventing the brake block from propelling away from a surface of the brake wheel by the restoring spring, preventing the brake block from rubbing against the first side panel.Type: ApplicationFiled: November 19, 2018Publication date: March 21, 2019Applicant: YOKE INDUSTRIAL CORP.Inventor: Eason Sun
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Publication number: 20190083829Abstract: The present invention relates to a clock-type disaster preparedness kit. More particularly, the present invention relates to a clock-type disaster preparedness kit in which a clock is integrated with a configuration for storing disaster preparedness goods such that a location of the disaster preparedness goods is easily recognized whereby it is possible to request rescue promptly in an emergency. Accordingly, the present invention provides the clock-type disaster preparedness kit, the kit including: a housing provided with a storage space in which a first portion and a second portion thereof are engaged with each other; a clock provided on an outer surface of the housing and showing time; a storing portion provided in the second portion of the housing and storing disaster preparedness goods; and a coupling member coupling the first portion and the second portion of the housing to combine the housing.Type: ApplicationFiled: September 18, 2018Publication date: March 21, 2019Inventors: Eun A Kim, Kyung Hun Yim, Suk Woo Lee
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Publication number: 20190083830Abstract: A flexible bag includes an inner compartment for receiving a hot and/or burning object, the bag being able to be rolled up and/or folded, and including an opening for insertion of the object into the inner compartment. The flexible bag further includes an outer compartment that can be accessed from the exterior where the outer compartment is provided on the third of the bag lying opposite the opening and where a fire extinguisher is housed in the outer compartment in order to hold and dispense a fire-extinguishing agent.Type: ApplicationFiled: March 30, 2017Publication date: March 21, 2019Applicant: SACS GmbHInventors: Jan SCHOLTENS, Claude VALERIUS, Joseph SCHNOELL