Patents Issued in April 16, 2019
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Patent number: 10258722Abstract: The illustrative embodiments described herein are directed to systems, methods, and apparatuses for applying a reduced pressure to a subcutaneous tissue site. In one instance, a manifold for applying reduced pressure to a subcutaneous tissue site includes a plurality of first conduits, each of the plurality of first conduits having a wall with at least one first aperture and at least one second aperture. At least one of the plurality of first conduits is operable to deliver reduced pressure to the subcutaneous tissue site. The plurality of first conduits is coupled in a spaced arrangement that forms an interior space. The manifold further includes a second conduit comprising the interior space and formed by a portion of each wall of the plurality of first conduits. The second conduit is in fluid communication with the plurality of first conduits via the at least one second aperture.Type: GrantFiled: September 17, 2014Date of Patent: April 16, 2019Assignee: KCI Licensing, Inc.Inventors: Justin Alexander Long, Michael E. Manwaring, Douglas A. Cornet
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Patent number: 10258723Abstract: A breast milk collection device includes a reservoir volume and an adaptor having one end to receive a woman's breast. The adaptor has a drip tube communicating with the reservoir. A source of cyclical application and relief of vacuum force is applied to the woman's breast located in the adaptor for the expression of breast milk. A one-way assembly permits breast milk to enter the reservoir and to submerge the valve element. The valve assembly includes a flexible barrier having an interior hollow chamber in fluid communication with said cyclical source of vacuum force and relief pressure, the flexible barrier fluidly isolating the source from the reservoir. The flexible barrier inflatably expands when relief pressure is applied to the interior of the flexible barrier, the flexible barrier becoming deflated when a vacuum force is applied to the hollow interior of the flexible barrier.Type: GrantFiled: July 8, 2016Date of Patent: April 16, 2019Assignee: Dao HealthInventors: Dan Garbez, Stella Dao, Dave Paul, Ben Sutton
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Patent number: 10258724Abstract: The present disclosure provides for methods and devices for determining the probability of a patient's aortic valve being open or closed. In one embodiment, a plurality of flow rate data points are obtained from a blood pump, a portion of the flow rate data points are identified, first and second index values characterizing properties of at least part of the identified portion of the flow rate data points determined using only arithmetic and/or exponentiation operations, and a probability is determined of whether the patient's aortic valve is open or closed based on the first and second index values.Type: GrantFiled: July 31, 2017Date of Patent: April 16, 2019Assignee: HeartWare, Inc.Inventors: Zoe Demou, Carlos Reyes, Pedro Grave De Peralta
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Patent number: 10258725Abstract: The present invention relates to extracorporeal blood treatment devices and methods and devices for conserving extracorporeal blood treatment devices. In accordance with the present invention, an antifreeze agent in introduced only into that part of the dialysis liquid system of the blood treatment device that includes the volume lying upstream of a sterile filter with which sterile substituate is recovered from the dialysis liquid. Accordingly, that part of the dialysis liquid system that includes the volume lying downstream of the sterile filter is not filled with an antifreeze agent. The present invention makes it possible, after removal of the sterile filter, to easily and safely separate a substituate segment from the rest of the dialysis liquid system and drain off liquid located in the substituate segment.Type: GrantFiled: April 30, 2013Date of Patent: April 16, 2019Assignee: Fresenius Medical Care Deutschland GmbHInventor: Gerhard Wiesen
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Patent number: 10258726Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a filtration unit (2), a blood withdrawal line (6), a blood return line (7), an effluent fluid line (13), a pre and/or post-dilution fluid line (15, 25) connected to the blood withdrawal line, and a dialysis fluid line. Pumps (17, 18, 21, 22, 27) act on the fluid lines for regulating the flow of fluid. A control unit (10) is configured to periodically calculate a new value for the patient fluid removal rate to be imposed on an ultrafiltration actuator in order to keep a predefined patient fluid removal rate across a reference time interval irrespective of machine down times.Type: GrantFiled: August 18, 2016Date of Patent: April 16, 2019Assignee: Gambro Lundia ABInventor: Dominique Pouchoulin
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Patent number: 10258727Abstract: The invention relates to a disposable article for use in dialysis treatment which has at least one sensor for determining a measured value relating to the dialysis. The invention further relates to a dialyzer having a disposable article in accordance with the invention. The invention furthermore relates to a dialyzer and to a water preparation plant for dialysate having at least one sensor for determining at least one measured value relating to the dialysis, at least one transmitter which is connected to the sensor and is configured such that it enables a wireless transmission of the measured value to at least one receiver and at least one energy converter for providing energy, preferably electrical energy, to the sensor and to the transmitter.Type: GrantFiled: August 14, 2014Date of Patent: April 16, 2019Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventor: Benedict Glaser
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Patent number: 10258728Abstract: Systems and methods are provided for performing selective sorbent-based regeneration of dialysate. The systems and method provide for dialysate regeneration to be carried out intermittently throughout a dialysis session, decreasing the necessary amounts of sorbent materials and infusates to conduct dialysis. The system and methods allow for regeneration of dialysate as needed based on the concentration of waste species in the dialysate, allowing for effective treatment with a decreased need for sorbent materials.Type: GrantFiled: September 14, 2016Date of Patent: April 16, 2019Assignee: Medtronic, Inc.Inventor: Martin T. Gerber
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Patent number: 10258729Abstract: A method for pumping and oxygenating blood includes receiving a flow of gas including oxygen into a gas inlet manifold via a gas inlet. The flow of gas is passed through the hollow fibers from the gas inlet manifold to a gas outlet manifold. The flow of gas is output from the gas outlet manifold via a gas outlet. An impeller is rotated to generate a flow of blood that flows over the hollow fibers. Oxygen from the flow of gas is transferred to the flow of blood through the hollow fibers. Carbon dioxide is transferred from the flow of blood to the flow of gas through the hollow fibers.Type: GrantFiled: January 28, 2016Date of Patent: April 16, 2019Assignees: Thoratec LLC, University of Maryland, BaltimoreInventors: Barry N. Gellman, Andrew Koert, Zhongjun Wu, Juntao Zhang, Bartley P. Griffith
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Patent number: 10258730Abstract: The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min, wherein the force on the upper bearing is less than 3 N during operating speeds up to 6000 rpm. The rotary blood pump is part of a blood pump system that includes blood conduit(s), a control system with optional sensors, and a power source.Type: GrantFiled: May 26, 2017Date of Patent: April 16, 2019Inventors: F. Nicholas Franano, Howard M. Loree, II, Geoff Tansley, Steve Woodard, Barrett Hutto
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Patent number: 10258731Abstract: The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The manifold includes diaphragms adapted to minimize the dead space between the dialysis machine pins and improve responsivity. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface and a heater in thermal communication with the container. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.Type: GrantFiled: February 29, 2016Date of Patent: April 16, 2019Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Barry Neil Fulkerson, Alec Huang, Brian Thomas Kelly
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Patent number: 10258732Abstract: A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures. In one embodiment, the split-tip catheter includes a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region includes an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion may taper distally from a first outer perimeter to a second outer perimeter smaller than the first outer perimeter.Type: GrantFiled: January 8, 2016Date of Patent: April 16, 2019Assignee: C. R. Bard, Inc.Inventors: Colin S. Gregersen, Ryan T. Moehle, Ryan C. Patterson
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Patent number: 10258733Abstract: An apparatus is described for extracorporeal blood treatment, comprising a treatment unit, an extracorporeal blood circuit and a fluid evacuation line. The apparatus comprises a control unit connected to a pressure sensor and a blood pump, the blood pump generating a variable flow with a constant component and a variable component. The control unit receives, from the pressure sensor, a plurality of values and calculates the average pressure value, acquires an estimated value of volume variation in the expansion chamber connected to the variable flow component, calculates, as a function of the pressure values, an estimated value of pressure variation in the expansion chamber that is representative of an oscillating pressure component and determines a representative magnitude of a blood level in the expansion chamber as a function of the average pressure value, the estimated value of volume variation and the estimated pressure variation in the expansion chamber.Type: GrantFiled: August 2, 2017Date of Patent: April 16, 2019Assignee: Gambro Lundia ABInventor: Alessandro Vasta
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Patent number: 10258734Abstract: A method of modifying cells includes removing fluid including cells from a patient, contacting the removed fluid from the patient with at least one surface upon which at least one agent to interact at least one cell receptor is immobilized to modify cells in the fluid, and returning the fluid to the patient. The agent can, for example, be immobilized via covalent bonding or ionic bonding to the at least one surface. The fluid can, for example, be blood or a blood fraction. The agent can, for example, be an agonist, an antagonist or an inverse agonist.Type: GrantFiled: March 8, 2017Date of Patent: April 16, 2019Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: William J. Federspiel, John Alston Kellum, Kai Singbartl
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Patent number: 10258735Abstract: A medicament delivery device includes a housing, a medicament container disposed within the housing, an activation mechanism, a cover and an electronic circuit system. The activation mechanism includes an energy storage member configured to produce a force to deliver the dose of a medicament and/or vaccine. The cover is configured to receive at least a portion of the housing. The electronic circuit system is coupled to the housing such that a protrusion of the cover electrically isolates a battery from a portion of the electronic circuit system when the portion of the housing is received by the cover. The electronic circuit system is configured to be electrically coupled to the battery and to produce a recorded speech output when the portion of the housing is at least partially removed from the cover. The electronic circuit system configured to produce a signal when the activation mechanism is actuated.Type: GrantFiled: November 4, 2016Date of Patent: April 16, 2019Assignee: kaleo, Inc.Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, David A. Weinzierl
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Patent number: 10258736Abstract: Devices and methods are disclosed for transferring fluids from supply reservoirs. The devices and methods may be configured to prevent or reduce the incidence of a user transferring a fluid to an incorrect receptacle reservoir.Type: GrantFiled: January 4, 2017Date of Patent: April 16, 2019Assignee: Tandem Diabetes Care, Inc.Inventors: Thomas Metzmaker, Sean Saint, Michael Michaud, Michael J. Rosinko, Vance Swanson
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Patent number: 10258737Abstract: Disclosed is a skin adherable device for delivering therapeutic fluid into a body of a patient. The device includes a monitoring apparatus, a dispensing apparatus, and a tip for delivering the therapeutic fluid into the body of the patient and for monitoring bodily analyte in the body of the patient. The dispensing apparatus may continuously deliver the therapeutic fluid to the body of the patient and the monitoring apparatus may continuously monitor bodily analytes of the patient.Type: GrantFiled: September 8, 2015Date of Patent: April 16, 2019Assignee: Roche Diabetes Care, Inc.Inventors: Ofer Yodfat, Ruthy Kaidar
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Patent number: 10258738Abstract: Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor.Type: GrantFiled: April 21, 2017Date of Patent: April 16, 2019Assignee: Chrono Therapeutics Inc.Inventors: Guy DiPierro, Steven A. Giannos
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Patent number: 10258739Abstract: A mechanical driver comprising a wedge shaped member operatively coupled to a shape memory alloy such that the shape memory alloy is able to displace the wedge shaped member in an essentially linear direction. The wedge shaped member is in constant contact with a lever arranged so that it can rotate about a fixed pivot point. A piston is arranged such that it is constant contact with the lever at a point between the pivot point of the lever and the contact point between the lever and the wedge shaped member. Activation of the shape memory alloy displaces the wedge shaped member along its linear direction and this causes the lever to be deflected about its pivot point and the piston to be deflected in an essentially linear direction that is perpendicular to the linear direction of travel of the wedge shaped member.Type: GrantFiled: November 23, 2016Date of Patent: April 16, 2019Assignee: ViCentra B.V.Inventor: Joseph John Cefai
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Patent number: 10258740Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof; a hollow needle at a front end of the barrel, the hollow needle defining a needle tip; and a plunger that is axially movable within the barrel. The cassette unit includes, in contact with the plunger and axially movable within the barrel, a plunger slaving part arranged such that when a drive load is applied to a rear drive-receiving face thereof the drive load is evenly transmitted to the plunger.Type: GrantFiled: June 4, 2012Date of Patent: April 16, 2019Assignee: UCB BIOPHARMA SPRLInventors: Martin John McLoughlin, Darrell P. Morgan, Kevin Richard Lozeau, Agnete Enga, Eric Freitag, Daniel Formosa, Michael Schumann, Brian Lipford, Jake Cowperthwaite, Alex Flamm, Ilario Melzi, Jonathan Bodnar
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Patent number: 10258741Abstract: Embodiments of the present invention relate to a microfluidic flow restrictor having a converging tapered inlet connected by a constant internal diameter section to a diverging tapered outlet having an outlet face and a smooth and gradual transition from the constant internal diameter section to the outlet face. This dual tapered capillary flow restrictor may be incorporated into a system such as a microfluidic circuit. Using a dual tapered capillary for accurate flow control together with a constant pressure source provides a more steady flow with reduced flow fluctuation caused by bubbles passing or pinning to the capillary end-face. Further, when connected in series, these dual tapered capillary flow restrictors may reduce noise in flow and pressure measurements, reduce bubble segmentation, and reduce bubble pinning.Type: GrantFiled: December 28, 2016Date of Patent: April 16, 2019Assignee: CeQur SAInventors: Peter Gravesen, Bo F. Madsen
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Patent number: 10258742Abstract: A method for readying a fluid sensor associated with a medical device includes attaching a flow restrictor to a fluid outlet of the fluid sensor. The fluid sensor includes a fluid channel, a fluid inlet at a first end of the fluid channel configured to couple to an outlet of an administrable fluid source, and the fluid outlet at a second end of the fluid channel. Fluid is delivered from the administrable fluid source to the fluid channel through the fluid inlet. A syringe actuation device including a force limiting device may be used to deliver the fluid. The fluid is pressurized in the fluid channel between the fluid inlet and the flow restrictor to wet an interior surface of the fluid channel with the fluid. The flow restrictor is removed from the fluid outlet.Type: GrantFiled: June 19, 2017Date of Patent: April 16, 2019Assignee: Becton, Dickinson and CompanyInventors: Kaushal Verma, Brandi Ford, Shawn Wayne DeKalb, Hong Zhu
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Patent number: 10258743Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.Type: GrantFiled: April 3, 2017Date of Patent: April 16, 2019Assignee: Common Sensing Inc.Inventors: Richard Whalley, James White
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Patent number: 10258744Abstract: A pharmaceutical syringe piston having a longitudinal axis includes a body having a central face portion with a first outer circumference and maximum first diameter. A cylindrical sealing portion proximate the central face portion has first and second axial ends and a wall extending therebetween. The wall has a second outer circumference and a second diameter essentially constant along the longitudinal axis between the first and second axial ends of the cylindrical sealing portion and is larger than the maximum first diameter. An annular curved portion has a maximum outer diameter less than the second diameter and connects the first axial end of the cylindrical sealing portion to the first outer circumference. An inert film encloses the central face portion and at least a part of the annular curved portion and has an outer boundary between the first axial end of the cylindrical sealing portion and the first outer circumference.Type: GrantFiled: April 5, 2013Date of Patent: April 16, 2019Assignee: West Pharmaceutical Services, Inc.Inventors: Jeffrey M. Laubach, Jurgen Brinkhues, Heike Gruen, Joel Worman, Xia Zhao, Jason Mattia
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Patent number: 10258745Abstract: Disclosed are systems and methods of detecting an impulse of energy given off by an injection device and determining a dosage of medicine based on the impulse. In one example, a module detects the vibrations given off by dialing a click-wheel on an autoinjector and determining the selected dosage of medicine based on the dialed dosage.Type: GrantFiled: January 21, 2016Date of Patent: April 16, 2019Assignee: Becton, Dickinson and CompanyInventors: Mircea Stefan Despa, Harry Bullivant, Andrew Richards, Michael Allan, Mark Hsieh, Sundeep Kankanala, Dylan Wilson
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Patent number: 10258746Abstract: An apparatus and method of automatically and safely removing a needle from a syringe assembly while retaining a syringe hub as part of the syringe assembly is generally described. A needle containment device is provided, which may include a needle handling apparatus and a shutter mechanism assembly. The needle handling apparatus is configured for receiving at least a portion of a syringe assembly including at least a needle and a syringe hub, wherein a first clamping mechanism is configured to clamp the syringe hub and a second clamping mechanism is configured to clamp the needle, so that the needle is safely and automatically removed from the syringe hub.Type: GrantFiled: March 19, 2015Date of Patent: April 16, 2019Assignee: Inventive Medical Devices, LLCInventors: Reza Radmand, Ali Moghadam
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Patent number: 10258747Abstract: A method for manufacturing a needle-equipped outer tube includes providing a needle; providing a joint member having a needle insertion hole into which the needle is insertable; providing an outer tube comprising a connection section at a first axial end portion of the outer tube; pressing the joint member, with the needle located in the needle insertion hole, toward the connection section, such that the joint member engages with the connection section of the outer tube; and thermally welding the needle and the joint member, as well as the joint member and the connection section, such that the needle is joined to the joint member, and the joint member is joined to the connection section of the outer tube.Type: GrantFiled: April 24, 2014Date of Patent: April 16, 2019Assignee: TERUMO KABUSHIKI KAISHAInventors: Kozo Matsumoto, Masaaki Kasai, Tsutomu Sugiki
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Patent number: 10258748Abstract: A portable handheld vein-image-enhancing device broadly includes: a first laser emitting a beam of light at a first wavelength; a second laser emitting a beam of light at a second wavelength; a scanner to scan the beams of light onto the target surface; a photo detector to receive the reflected vein image and convert the image into a signal, for use by the second laser and scanner to project the image onto the target surface; and a user interface and electronic circuitry to permit adjustments to one or more of the following imaging parameters: a vein size parameter to set a vein size to be imaged by the device; a field of view size; a size for a field of high resolution for the projected image; a brightness of the projected image; and a laser output intensity parameter setting a depth of penetration by the first wavelength for the imaging.Type: GrantFiled: December 22, 2015Date of Patent: April 16, 2019Assignee: AccuVein, Inc.Inventors: Fred Wood, Ron Goldman, Stephen P Conlon, Vincent Luciano
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Patent number: 10258749Abstract: A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.Type: GrantFiled: December 8, 2015Date of Patent: April 16, 2019Assignee: Becton, Dickinson and CompanyInventors: Ryan Schoonmaker, Michel Bruehwiler, Ira Spool, Melissa Rosen
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Patent number: 10258750Abstract: An example medical device includes a body portion having a tubular inner wall defining an inner channel, and a tubular outer wall encircling the inner wall. The outer wall defines an outer channel between the outer wall and the inner wall. The body portion also includes an indicator substance disposed within the outer channel. The device also includes an indicator portion defining an indicator channel. The body portion is configured to insert at least in part into a patient, and the indicator portion is configured to remain at least in part along an exterior of the patient when the body portion is inserted into the patient. The device is also configured to transfer at least a portion of the indicator substance from the outer channel to the indicator channel when the body portion is bent.Type: GrantFiled: November 16, 2016Date of Patent: April 16, 2019Assignee: KLOSE Monitoring, LLCInventor: Kashif Latif
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Patent number: 10258751Abstract: A dry-powder inhalation device including a casing having at least one push button located on an external portion thereof, the push button including at least one pin structure, an air inlet located at a first terminus of the casing; a powder delivery port located at a second terminus of the casing and is positioned distal to the air inlet; and an elongated support panel located within an interior of the casing and being fitted within the casing so as to partially rotate therein about a single axis. The support panel has at least one compartment containing dry-powder located proximal to the first terminus, and the at least one pin structure is located proximal to the air inlet and arranged above the dry-powder compartment.Type: GrantFiled: October 20, 2014Date of Patent: April 16, 2019Assignee: Seroton, Inc.Inventors: David R. Elmaleh, Maxim D. Elmaleh
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Patent number: 10258752Abstract: Embodiments of an inhaler device include a housing, a withdrawing assembly disposed within the housing for facilitating withdrawal of medicament from a target blister of a blister strip, the withdrawing assembly including an opening element adapted for opening the target blister of the blister strip while the target blister is positioned in the withdrawing assembly, and a dispensing element adapted for directing the withdrawn medicament toward the exterior of the inhaler device. A blister track is disposed within the housing for guiding each blister of the blister strip to the withdrawing assembly in succession, an advancing mechanism for advancing the blister strip by a predetermined distance each time the advancing mechanism is engaged, and an engaging element for engaging the advancing mechanism to advance the blister strip. The blister track includes a primary coil structure, a secondary coil structure, and a tertiary coil structure.Type: GrantFiled: September 25, 2014Date of Patent: April 16, 2019Assignee: Novartis AGInventors: Mark Glusker, Victoria Quitugua
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Patent number: 10258753Abstract: An inhalation training system and a method for practicing of an inhalation process and a method of operating a portable communications device in this respect and to an information storage medium are improved. An air flow during inhalation is converted into an acoustic signal, especially a whistling tone. The acoustic signal is picked up by a microphone of a portable communications device, such as a smartphone, and is electronically evaluated. The inhalation training system has a mouthpiece and a converter apparatus for converting the air flow into the acoustic signal and in addition has a holding apparatus for especially detachable holding of the communications device.Type: GrantFiled: October 2, 2013Date of Patent: April 16, 2019Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Patricia Adams, Marion Frank, Herbert Wachtel
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Patent number: 10258754Abstract: Apparatus and methods are disclosed for controlling pressure delivery to a user such as a patient. A flow generator generates an outlet flow at an outlet port for delivery to a patient. At least one sensor measures properties of the flow of gas at the outlet port or being delivered to the patient. A controller is operatively connected to the flow generator and the at least one sensor, and is adapted to operate according to a pressure control mode in which the controller controls the flow generator to output a substantially steady pressure or a flow control mode in which the controller controls the flow generator to output a substantially steady flow. The controller operates in the flow control mode when a patient may be awake and in the pressure control mode when the patient may be asleep.Type: GrantFiled: August 12, 2011Date of Patent: April 16, 2019Assignee: Fisher & Paykel Healthcare LimitedInventors: Christopher Earl Nightingale, Donald Roy Kuriger
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Patent number: 10258755Abstract: A multi-functional oropharyngeal airway device designed to be inserted into the peripheral portion of a patient's oral airway to establish and maintain that airway. The components comprising the invention are a non-compressible, hollow cylinder body with at least three different and commonly used medical connectors incorporated into the proximal end of the body, and a flexible tube incorporated into the distal end of the body. The specific geometry and inclusion of the components of the airway device are arranged to be inserted and affixed into a peripheral position in a patient's mouth.Type: GrantFiled: December 1, 2017Date of Patent: April 16, 2019Inventors: Jeffrey Lee Dexter, John Paul Dexter
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Patent number: 10258756Abstract: An atraumatic nasal tube for non-invasive respiratory support (NIV-CPAP), having one central tube (5) extending from the nasal bridge, at a distance from the forehead area, to the nasal opening of the patient. The first end of the central tube (5) has an applicator (2) to be fixed to the forehead of the patient for connecting to a hose system coupled to a respiratory machine, and the second end of the central tube (5) comprises nasal connectors (6) protruding in a sickle shape out of the central tube (5) and opening into the nasal opening.Type: GrantFiled: April 1, 2010Date of Patent: April 16, 2019Assignee: F. Stephen GmbH MedizintechnikInventors: Georg Mainusch, Peter Schaller
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Patent number: 10258757Abstract: A patient interface has a single loop headstrap and a mask for covering at least the nostrils of the user. The single loop headstrap extends from the mask at either end. A short length of supple conduit is coupled to the mask by a swivel or ball joint to allow rotation of the conduit relative to the mask through different angles and orientations.Type: GrantFiled: January 18, 2017Date of Patent: April 16, 2019Assignee: Fisher & Paykel Healthcare LimitedInventors: Olivia Marie Allan, Arvin San Jose Gardiola, Lewis George Gradon, Wen Dong Huang, Alastair Edwin McAuley, Mark Arvind McLaren, Craig Robert Prentice, Andrew Paul Maxwell Salmon, Silas Sao Jin Siew
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Patent number: 10258758Abstract: The invention relates to a flow controlled valve system. The flow controlled valve may be incorporated into a pre-filled, small-volume nebulizer assembly with a T-connector. The flow controlled valve allows different airflow characteristics in each direction. The flow controlled valve also facilitates breathing physiotherapy by creating different airflow resistances during inhalation and exhalation.Type: GrantFiled: April 20, 2018Date of Patent: April 16, 2019Assignee: Caddo Medical Technologies LLCInventors: Joseph Dee Faram, Evan Dyer Faram
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Patent number: 10258759Abstract: A bi-level positive airway pressure device includes a housing that has a patient port for connecting to an airway of a patient. Within the housing is a device that generates a positive airway pressure directed towards to patient port. Also within the housing is a system that mechanically detects exhalation (by the patient that is connected to the patient port) that enters into the patient port. Responsive to detecting exhalation, a blocking device occludes the device that generates positive airway pressure, thereby reducing or stopping the positive airway pressure until the system that mechanically detects exhalation no longer detects exhalation, at which time the blocking device is operated to no longer occlude the device for generating positive airway pressure, thereby providing positive airway pressure to the patient port during, for example, inhalation.Type: GrantFiled: September 14, 2015Date of Patent: April 16, 2019Assignee: MERCURY ENTERPRISES, INC.Inventor: Jeffrey B. Ratner
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Patent number: 10258760Abstract: Computer implemented method and system for achieving a preferred state of mind of a user are disclosed. In a first aspect, the method comprises detecting a biological marker (biomarker) of a user utilizing one or more sensors; and inferring a state of mind of the user based upon data received from the one or more sensors that are provided to computational hardware. Finally the method includes providing an antidote to the user if the inferred state of mind is different than the preferred state of mind utilizing an actuator. In a second aspect, the system comprises one or more sensors for detecting a biological marker (biomarker) of the user and computational hardware for inferring a state of mind of the user based upon data received from the one or more sensors. Finally the system includes an actuator for providing an antidote to the user if the inferred state of mind is different than a preferred state of mind.Type: GrantFiled: December 23, 2016Date of Patent: April 16, 2019Assignee: AlayaTec, Inc.Inventors: Trungram Gyaltrul R. Sherpa, David H. C. Chen
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Patent number: 10258761Abstract: A children's soothing device, such as a motorized swing, a motorized glider, a motorized rocker, a motorized bouncer, a playard, a crib, a car seat, a stroller, an infant carrier, or a bassinet, can include one or more speakers, one or more vibrating motors or solenoids, and one or more light attractions or lights for soothing a child. The children's soothing device can include a control system for storing and reading sound and other data files to output music or other sounds through the speakers and to activate and deactivate the vibrating motors in a synchronized pattern with the sound or music. The children's soother device can also evaluate the sound and other data files to synchronize the activation, deactivation, and/or change of state of the light attraction or lights with the sound/music and the vibrating motors.Type: GrantFiled: April 13, 2016Date of Patent: April 16, 2019Assignee: GRACO CHILDREN'S PRODUCTS INC.Inventor: Bart A. Smudde
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Patent number: 10258762Abstract: A sleep support apparatus includes a pair of electrocardiographic electrodes that detect an electrocardiographic signal, a photoelectric pulse wave sensor that includes a light emitter and a light receiver and that detects a photoelectric pulse wave signal, peak detectors that respectively detect the peaks of the electrocardiographic signal and the photoelectric pulse wave signal, a pulse wave transit time clock that obtains a pulse wave transit time from a time difference between the peak of the photoelectric pulse wave signal and the peak of the electrocardiographic signal, a sleep state detector that determines that a user's body has not reached a state suitable for sleep when the pulse wave transit time is less than or equal to a certain threshold, and a forearm heater that increases a temperature of a forearm when it is determined the user's body has not reached a state suitable for sleep.Type: GrantFiled: September 19, 2016Date of Patent: April 16, 2019Assignee: MURATA MANUFACTURING CO., LTD.Inventor: Toru Shimuta
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Patent number: 10258763Abstract: A method of manufacturing a catheter shaft includes extruding an inner polymeric layer having a main lumen and two or more side lumens spaced about the main lumen; forming an outer polymeric layer about the inner polymeric layer; and inserting at least one elongate member, such as a wire, through each side lumen of the inner polymeric layer. The side lumens are less than about ? the size of the main lumen. The method may further include the step of forming a braided layer between the inner polymeric layer and the outer polymeric layer. In an alternate embodiment, the method includes co-extruding an inner polymeric layer and a multi-lumen layer, the multi-lumen layer having two or more side lumens; forming an outer polymeric layer about the multi-lumen layer; and inserting at least one elongate member through each side lumen. Catheter assemblies made according to the described methods are also disclosed.Type: GrantFiled: January 6, 2017Date of Patent: April 16, 2019Assignee: St. Jude Medical, Atrial Fibrillation, Inc.Inventors: Martin Maitre Grasse, James V. Kauphusman
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Patent number: 10258764Abstract: A ball-tipped mandrel, separate or integrated on a device delivery assembly, can be used to ease delivery and/or retrieval of an ancillary device within a body vessel having tortuous anatomy. A ball-tipped mandrel can be moved through a catheter as a part of a preparation procedure prior to insertion into a body vessel of a patient. A ball-tipped mandrel can be moved through a catheter during or after insertion into a body vessel of a patient in preparation for delivery of an ancillary device. A ball-tipped mandrel can be integrated onto the distal portion of a device to produce dilation during device delivery.Type: GrantFiled: July 30, 2014Date of Patent: April 16, 2019Assignee: Covidien LPInventors: Michael Losordo, Evan Epstein
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Patent number: 10258765Abstract: A cable includes a silicone rubber coating including microparticles and cavities as an outermost coating. A medial hollow tube includes a silicone rubber coating including microparticles and cavities as an outermost coating or an innermost coating. The microparticles may be at least one kind of microparticle selected from silicone resin microparticle, silicone rubber microparticle and silica microparticle. The microparticles may have hardness higher than a hardness of silicone rubber constituting the silicone rubber coating.Type: GrantFiled: July 25, 2017Date of Patent: April 16, 2019Assignee: HITACHI METALS, LTD.Inventors: Seiichi Kashimura, Takanobu Watanabe, Kimika Kudo, Masamichi Kishi
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Patent number: 10258766Abstract: The application relates to a tube for being introduced into an object. The tube (1), which is preferentially a catheter, comprises a tube-like braid (2) made from electrically conductive strands (3), wherein ends (4) of the strands (3) are staggered in the longitudinal direction of the tube (1). Since the ends of the strands are staggered in the longitudinal direction of the tube, local radio frequency heat generated during a magnetic resonance imaging procedure is not concentrated at a single longitudinal location, but distributed along a staggered region in the longitudinal direction of the tube, in which the ends of the electrically conductive strands are staggered. This distribution of the radio frequency heat along the longitudinal direction of the tube reduces the maximum temperature produced by radio frequency heating and, thus, the likelihood of damaging the object, in which the tube is to be introduced, due to heat.Type: GrantFiled: November 29, 2012Date of Patent: April 16, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventor: Steffen Weiss
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Patent number: 10258767Abstract: A catheter having a catheter shaft and a tip. The catheter shaft includes an inner layer, a first reinforcing layer disposed around an outer periphery of the inner layer, an intermediate layer, a second reinforcing layer disposed around an outer periphery of the intermediate layer, and an outer layer that covers the second reinforcing layer. The tip includes a proximal end portion that extends in an axial direction of the catheter and is joined to at least the intermediate layer and the outer layer, between the first reinforcing layer and the second reinforcing layer. The proximal end portion increases the joining strength between the intermediate layer and the tip and the joining strength between the outer layer and the tip. As a result, it is possible to prevent the tip from easily detaching from the catheter shaft.Type: GrantFiled: March 17, 2017Date of Patent: April 16, 2019Assignee: ASAHI INTECC CO., LTD.Inventor: Hirotomo Shimizu
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Patent number: 10258768Abstract: Catheter apparatuses, systems, and methods for introducing a catheter into a patient's body. In one embodiment, a catheter apparatus includes a catheter body having a first lumen capable of fluid communication via a first distal opening and a second lumen capable of fluid communication via a second distal opening, a first intra-catheter stiffener element for disposition through the first lumen such that a distal end thereof is distal in relation to the first distal opening, and a second intra-catheter stiffener element configured for disposition through the second lumen such that a distal end thereof is distal in relation to the second distal opening, one of the first intra-catheter stiffener element distal end and the second intra-catheter stiffener element distal end capable of receiving and accommodating the other of the first intra-catheter stiffener element distal end and the second intra-catheter stiffener element distal end.Type: GrantFiled: July 14, 2015Date of Patent: April 16, 2019Assignee: C. R. Bard, Inc.Inventors: German Loesener, Ericka J. Prechtel
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Patent number: 10258769Abstract: An elongate medical device having an axis comprises an inner liner, a jacket radially outward of the liner, a braid comprising metal embedded in the jacket, a sensor, and at least one wire electrically connected to said sensor. The at least one wire is one of: embedded in the jacket and optionally disposed helically around the braid; extending longitudinally within a tube which extends generally parallel to the device axis and wherein the tube is embedded in the jacket; and disposed within a lumen, wherein the lumen extends longitudinally within the jacket.Type: GrantFiled: October 3, 2016Date of Patent: April 16, 2019Assignee: St. Jude Medical International Holding S.á r.l.Inventors: Ran Sela, Lior Sobe, Dan Seter
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Patent number: 10258770Abstract: A recanalization catheter for facilitating re-entry into a lumen of a blood vessel from a subintimal space. The catheter includes an inflatable balloon mounted on a distal end region of the catheter shaft of the catheter. The catheter shaft includes a guidewire lumen having a distal opening and a lateral opening in a distal region of the catheter shaft proximal of the distal opening, and an inflation lumen in fluid communication with the balloon. The balloon is configured to be inflated in the subintimal space to a first inflation state at inflation pressures below a threshold inflation pressure to orient the lateral opening toward the lumen of the blood vessel, and inflated to a second inflation state at inflation pressures above the threshold inflation pressure. The catheter includes means for retaining the balloon in the first inflation state at pressures below the threshold inflation pressure.Type: GrantFiled: March 11, 2014Date of Patent: April 16, 2019Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Huisun Wang, Pu Zhou, Benjamin Gundale, Daniel Horn, John Chen
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Patent number: 10258771Abstract: An introducer assembly includes a sheath and a tubular member that are coupled by a movement that is simultaneously longitudinal and radial.Type: GrantFiled: October 3, 2015Date of Patent: April 16, 2019Assignee: Teleflex Medical IncorporatedInventors: Jason Ryan Beissel, Todd Raymond Hilbert