Abstract: Methods and systems for tracking ocular vergence movements of an eye of a person are described. The methods and systems involve placement of flexible/stretchable skin-like electrodes on a person's head and recording the biopotential or electrooculogram of the person as the eye or eyes move to different focal positions, such as near distances, intermediate distances, and far distances. A data acquisition unit can record the electrooculogram and transmit the electrooculogram data to a computer for classification or for further processing. The data can be used with ophthalmic devices to provide a visual change for a person with the ophthalmic device.

Abstract: Improved scanning ophthalmoscopes for scanning the retina of an eye are discussed in the present disclosure. One example scanning ophthalmoscope includes an uncollimated light source, a first scanning element, a second scanning element, a slit of a first aspherical mirror, and a second aspherical mirror. The uncollimated light source produces a beam of light to illuminate the retina. The beam of light is relayed from the first scanning element onto the second scanning element by the slit of the first aspherical mirror. The second aspherical mirror relays the beam of light from the second scanning element to the pupil of the eye.

Abstract: A portable retinal imaging device for imaging the fundus of the eye. The device includes an ocular imaging device containing ocular lensing and filters, a fixation display, and a light source, and is configured for coupling to a mobile device containing a camera, display, and application programming for controlling retinal imaging. The light source is configured for generating a sustained low intensity light (e.g., IR wavelength) during preview, followed by a light flash during image capture. The ocular imaging device works in concert with application programming on the mobile device to control subject gaze through using a fixation target when capturing retinal imaging on the mobile device, which are then stitched together using imaging processing into an image having a larger field of view.

Abstract: An optical imaging system for an ophthalmic laser beam delivery system, which includes a focusing objective including a plurality of lenses, a semi-transparent folding mirror disposed near an entrance of the focusing objective for reflecting a treatment laser beam into the focusing objective, a prism disposed adjacent a back surface of the folding mirror, the prism having a first, a second and a third surface, the second surface being disposed adjacent the back surface of the folding mirror, the prism being configured to reflect a light that has entered the second surface sequentially by the first surface and by the second surface toward the third surface to be output, a focusing lens module disposed adjacent the third surface of the prism to focus light output from the third surface of the prism, and an image sensor disposed to receive the light focused by the focusing lens module to form an image.

Abstract: A tonometer for non-invasive measurement of intraocular pressure and or ocular durometer through a closed or open eyelid, and via sclera, includes a frame, a force sensor mounted with respect to the frame for measuring a force, a support structure mounted with respect to the frame, a position sensor mounted with respect to the frame, a movement mechanism, a contact tip, and a processing unit in communication with the force sensor and the position sensor, a memory unit, a display unit, a signaling mechanism, a power source, a power switch and a wireless communication module. A variant of the apparatus is also capable of functioning as a durometer measuring device to measure hardness of tissues such as wound tissue.

Abstract: A sensor (1) including: an acquisition unit (11) which can acquire patient identification information so that a patient can be identified by the acquired patient identification information; a storage unit (12) which stores the patient identification information acquired by the acquisition unit (11); a detection unit (13) which can detect vital information of the patient; an association unit (14) which associates the patient identification information stored in the storage unit (12), with the vital information; and a transmission unit (15) which can transmit the vital information including the associated patient identification information, to a bedside monitor.

Abstract: Devices, systems, and methods for measuring and monitoring biometric or physiological parameters in a user-friendly and convenient manner are disclosed. Relevant physiological parameters of the user may be measured as the user normally operates a computing device or other hand-operated or hand-held device. These parameters are measured using an accessory of the device such as a laptop case, a tablet computer case, a smartphone case, or a smart watch or smart armband. The accessory may include at least two or three electrodes for taking an electrocardiogram or other physiological parameters. The measured parameters are transmitted to the computing device. The computing device can be normally used while a physiological parameter monitoring and measurement application loaded onto the computing device operates in the background to receive the measured parameters.

Abstract: An example of a mobile computing device for managing medical equipment includes a display and a processor, a memory, and associated circuitry, the processor configured to receive patient data gathering device location information for a plurality of patient data gathering devices, the patient data gathering device location information being indicative of one or more patient data gathering device locations in an assigned monitoring area corresponding to the mobile computing device, control the display to provide the patient data gathering device location information, capture a user selection of at least one patient data gathering device of the plurality of patient data gathering devices based on the provided patient data gathering device location information, and provide patient data gathering device information based on the user selection.

Abstract: The present disclosure includes a host device that is part of a patient monitoring system. The host device can provide an improved, organized, uncluttered, and graphically-rich display that presents an integrated display of real-time patient data and alarms from multiple integrated or non-integrated devices, such as patient monitors, ventilators, anesthesia gas machines, or intravenous (IV) pumps. The host device may provide a supplementary display for the patient data collected by the multiple devices and present information, such as comprehensive real-time patient status, historical trends, or alarm indicators, in an organized manner for particular clinical scenarios. The one or more displays can be central to a care team for a patient, and the care team can together simultaneously view and act upon the information presented.

Abstract: A sensing device allows detection of biological quantities in ways that are minimally invasive. Micrometer or nanometer sized needles allow sensing of bodily fluids in a minimally invasive method. The device comprises electronics and power harvesting. Antennas or coils allow communication and power harvesting from an external device, which can be attached to smartphones to allow operation of a camera and camera light for biosensing.

Abstract: A computer-implemented method for decoding patient characteristics and brain state from multi-modality brain imaging data includes receiving a plurality of brain imaging datasets comprising brain imaging data corresponding to plurality of subjects. The brain imaging datasets are aligned to a common reference space and quantitative measures are extracted from each brain imaging dataset. Non-imaging characteristics corresponding to each subject are received and a forward model is trained to map the plurality of characteristics to the quantitative measures.

Abstract: A method for computing global longitudinal strain from cine magnetic resonance (MR) images includes automatically detecting landmark points in each MR long axis image frame included in a cine MR image sequence. A deformation field is determined between every pair of frames based on the landmark points. Myocardial pixels in the frames are labeled using a deep learning framework to yield myocardium masks. These myocardium masks are propagated to each frame using the deformation fields. A polar transformation is performed on each of the masked frames. The contours of the myocardium in each transformed frame are computed using a shortest path algorithm. Next, longitudinal strain is calculated at every pixel in the myocardium for the polar frames using the contours of the myocardium. Then, global longitudinal strain is computed by averaging the longitudinal strain at every pixel in the myocardium of the transformed frames.

Abstract: A method and system to identify function in areas of a cerebral cortex using optical coherence tomography to scan an area and compare the scan to a cytoarchitectural database of classified images. A matched image has an associated likely function. Using a navigation system, the location of the cerebral cortex scanned is determined and is associated with the likely function corresponding to the matched image. A registration module may generate an image, possibly including pre-operative scan data, of the cerebral cortex with likely functions indicated for the scanned locations.

Abstract: An optical apparatus has an OCT imaging apparatus with a first light source for low coherence light of wavelengths above a threshold wavelength and a signal detector that obtains an interference signal between low coherence light from the sample and low coherence light reflected from a reference. A surface contour imaging apparatus has a second light source that emits one or more wavelengths of surface illumination below the threshold wavelength, a camera to acquire images from illumination reflected from the sample and a probe that has a raster scanner wherein the low coherence light and the surface illumination share the same path from the raster scanner to the sample. A processor coordinates activation of the light sources, actuation of the scanner, and acquisition of data and the camera and follows instructions to display, store, or transfer images from the acquired data.

Abstract: A method for acquiring image data obtains, for an intraoral feature, optical coherence tomography (OCT) data in three dimensions wherein at least one dimension is pseudo-randomly or randomly sampled and reconstructs an image volume of the intraoral feature using compressive sensing, wherein data density of the reconstructed image volume is larger than that of the obtained OCT data in the at least one dimension or according to a corresponding transform. The method renders the reconstructed image volume for display.

Abstract: Provided is a fast parallel optical coherence tomographic image generating method including dispersing light into N spectral regions ??1 through ??N sequentially from a low wavelength to a high wavelength, the light being emitted from a broadband light source of a fast parallel optical coherence tomographic image generating apparatus, N being an integer greater than or equal to “2”, splitting the light emitted from the broadband light source to be incident on a sample and a reference mirror, partitioning the sample into N image regions P1 through PN, discretely controlling a beam scanner such that the light emitted from the broadband light source is incident on the sample at a position changed by a preset distance, acquiring an interference spectral image through interference light formed in response to interference of measurement light and reference light, and generating a tomographic image of the sample using the interference spectral image.

Abstract: Systems and method for optical examination of dental structures are disclosed. Light from an optical source is directed on a portion of a dental structure. Light received from the portion of the dental structure is analyzed to detect a condition of the dental structure.

Abstract: Heat sensors can be positioned within the esophagus of a patient so as to monitor temperature changes during ablation procedures in the heart. Some heat sensors can include a wire that defines an extended heat sensing region capable of detecting a change in the local temperature. Some heat sensors can be conformable to an inner surface of the esophageal wall to maintain contact therewith or to be in close proximity thereto.

Abstract: One variation of a method for detecting inflammation in a foot includes: accessing a first temperature measured through a left temperature sensor and a second temperature measured through a right temperature sensor at approximately a first time, the left temperature sensor arranged in a left sock and the right temperature sensor arranged in a right sock worn on the user's feet; calculating a baseline difference between the first and second temperatures based on confirmation of absence of inflammation in the user's left and right feet at the first time; accessing a third temperature measured through the left temperature sensor and a fourth temperature measured through the right temperature sensor at approximately a second time; and in response to a second temperature difference between the third and fourth temperatures differing from the baseline difference by more than a threshold difference, issuing an alarm through the user interface.

Abstract: A biological information measurement device operates using a battery as a power source, and enables the continuous measurement of biological information. The biological information measurement device is provided with: a battery charge level detection unit for detecting the charge level of the battery; a measurement control unit that ends measurement of biological information when the charge level of the battery falls below a threshold value during biological information measurement; and an information output unit that, when biological information measurement has been ended by the measurement control unit, outputs, to a display unit, information indicating the length of time over which biological information was measured.

Abstract: A system control unit in the biological information measurement device generates and reports measurement efficiency information indicating measurement efficiency for biological information included in biological information calculation results information, based on biological information calculation results information and pulse wave detection results information from a storage medium storing the biological information calculation results information and the pulse wave detection results information, said biological information calculation results information being information indicating the calculation results for biological information from a biological information calculation unit that calculates biological information based on pulse waves for each pulse detected for a living body, said biological information calculation results information including at least the biological information, and said pulse wave detection results information indicating results from pulse wave detection performed for calculating b

Abstract: Methods, systems, and devices are disclosed for wearable, real -time multimodal sensing of electrochemical and electrophysiological and/or physical parameters of a user. In some aspects, a multimodal sensor device includes a flexible substrate; an electrochemical sensor disposed on the substrate and including electrochemical sensing electrodes operable to measure an electrical signal corresponding to a reaction including a chemical substance via an electrochemical sensing electrode and an analyte at the electrochemical sensor; and an electrophysiological sensor including two or more electrodes disposed on the substrate to acquire an electrophysiological signal of the user, such that when the multimodal sensor device is electrically coupled to an electronics unit and adhered to the user, the device is operable to simultaneously monitor an electrochemical parameter and an electrophysiological parameter of the user.

Abstract: A biological information analysis device includes: an indicator extraction unit configured to extract, from time-series data regarding blood pressure waveforms consecutively measured by a sensor that is configured to be worn on a body part of a user and to be capable of non-invasively measuring a blood pressure waveform for each heartbeat, and from time-series data regarding breathing measured by a respiration sensor during a period of time corresponding to the time-series data regarding blood pressure waveforms, an indicator indicating the relationship between the user's breathing and changes in blood pressure; and a processing unit configured to perform processing that is based on the indicator thus extracted.

Abstract: A method and system for determining the state of a patients brain under anesthesia. The present invention recognizes that anesthesia compounds induce different signatures in physiological characteristics of the patient under anesthesia and aids interpretation of physiological characteristics and signatures therein based on a selected anesthesia compound. The present invention aids the monitoring and/or interpreting of the physiological characteristics to a state of the patient's brain.

Abstract: A physiological signal measurement device includes a shell, a pair of induction sheets mounted to the shell, and a circuit board assembly mounted in the shell. The circuit board assembly includes a microprocessor, a photoplethysmography sensor electrically connected with the microprocessor, and an electrocardio signal sensor. The photoplethysmography sensor senses photoplethysmography signals of blood vessels reflected by the finger parts. The electrocardio signal sensor is electrically connected with the microprocessor and the pair of the induction sheets. The pair of the induction sheets respectively contact with finger parts of two hands to form a loop for sensing trace amounts of electrical signals generated from heart beats.

Abstract: A method is disclosed for diagnosing and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a lesion distal to an aortailiac bifurcation is to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a lesion proximal to the bifurcation is to be treated next, then treating the lesions substantially continuously.

Abstract: A method is disclosed for diagnosing, validating and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a shorter lesion to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a longer lesion is to be treated next, then treating the lesions substantially continuously.

Abstract: A method is disclosed for diagnosing and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a lower stenosis rate lesion to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a higher stenosis rate lesion is to be treated next, then treating the lesions substantially continuously.

Abstract: A method is disclosed for diagnosing and treating a patient having lesions in both arteries of left and right lower limbs. By determining that a longer lesion to be treated first, catheters and an operation time can be reduced is to be treated first on a priority basis based on diagnostic data, deciding that a shorter lesion is to be treated next, then treating the lesions substantially continuously.

Abstract: According to an example embodiment, a technique in a monitoring device for remote monitoring of at least one vital sign of a living subject is provided, the technique including capturing one or more sensor signals that are descriptive of respective characteristics of a body of the subject from a distance, deriving, on basis of said one or more sensor signals, at least a first biometric signal that is descriptive of a second predefined vital sign of said subject for transmission to a server device, detecting presence of another monitoring device that is operating to derive a first biometric signal that is descriptive of a first predefined vital sign of the same subject for transmission to the server device, and controlling derivation of said first biometric signal in the detected another monitoring device in response to detecting said another device.

Abstract: A biological information measurement device includes: a pulse wave detection unit that continuously detects pulse waves from a living body; a biological information calculation unit that calculates biological information based on pulse waves detected by the pulse wave detection unit and stores, in a storage medium, biological information calculation results information including said biological information; a storage control unit that stores, in the storage medium, pulse wave detection results information by the pulse wave detection unit in order to calculate biological information included in biological information calculation results information; a measurement efficiency information generation unit that generates measurement efficiency information indicating measurement efficiency for biological information included in biological information calculation results information, generating same based on the biological information calculation results information and pulse wave detection results information; and a

Abstract: A method for measuring blood pressure includes: detecting a cardiac impendence signal and a pulse signal of a person to be tested, determining a starting point of time of ejection from the cardiac impendence signal, determining a reference point of time from the pulse signal, determining a transmission time of pulse wave from the starting point of time of ejection and the reference point of time, and determining blood pressure of the person to be tested from the transmission time and a time-blood pressure formula.

Abstract: The present disclosure relates to the field of early non-invasive diagnosis, and specifically, to a method of determining a virtual hepatic venous pressure gradient. The method includes: constructing a 3-dimensional (3D) hepatic vein-portal vein model; establishing a finite element division mathematical model; and applying fluid dynamics to compute and simulate a virtual hepatic venous pressure gradient (vHVPG). The method optimizes and improves a more complete 3D hepatic vein-portal vein model, finite element division, and fluid dynamic simulation computation, constructing and validating a new vHVPG determination technology providing better diagnosis, providing a safe, non-invasive, accurate, and quantitative method for early non-invasive diagnosis of a portal vein high pressure patient.

Abstract: A biological information analyzing device includes: an indicator extraction unit that extracts an indicator pertaining to a characteristic of a blood pressure waveform using data of the blood pressure waveform obtained by a sensor, which is worn on a user's body and can non-invasively measure the blood pressure waveform for each of heartbeats, continuously measuring the blood pressure waveform; and a processing unit that carries out a process based on the extracted indicator.

Abstract: A method of processing electrophysiological signals includes: receiving, over a limited time duration, sample electrocardiography (ECG) signals indicative of heart pulsatile activity occurring with a variable heart rate, wherein receiving the sample ECG signals is discontinued at an expiry of the limited time duration; receiving photoplethysmography (PPG) signals indicative of the heart pulsatile activity; determining a correlation between the sample ECG signals and the PPG signals; determining reconstructed ECG signals from the PPG signals as a function of the correlation between the sample ECG signals and the PPG signals; and estimating a heart rate variability of the variable heart rate as a function of the reconstructed ECG signals.

Abstract: A method of determining respiratory rate from a photoplethysmograph signal includes filtering the photoplethysmograph signal to create a filtered photoplethysmograph signal. The method also includes detecting peaks and valleys in the filtered photoplethysmograph signal to extract predetermined features from the filtered photoplethysmograph signal. The method also includes obtaining variation waveforms from the predetermined features. The method also includes removing outliers from each of variation waveforms. The method also includes interpolating for the outliers removed from each of the variation waveforms to acquire a frequency estimation of each of the variation waveforms. The method also includes determining a respiratory rate based on the frequency estimation of each of the variation waveforms. The method also includes determining a weighted average of the respiratory rate the variation waveforms to determine an estimated respiratory rate.

Abstract: A physiological information measurement apparatus includes a measuring section that acquires a physiological signal from a living body of a subject, a signal processor that produces a plurality of physiological signal waveforms based on the physiological signal acquired from the measuring section, and that identifies an arithmetic average waveform that is obtained by arithmetic averaging of the plurality of physiological signal waveforms, and information relating to arithmetic average dispersion, and a display that displays at least the information relating to the arithmetic average dispersion.

Abstract: Electronic medical records (EMRs) with the results of the monitoring can be stored in a cloud-computing environment. All communications with the cloud-computing environment are performed via a secure connection. Each of the EMRs can be associated with an identifier that is provided with the results of the monitoring data. The EMRs can be created, viewed, and modified using a mobile application. The mobile application can use a scanner in the mobile device on which the application executes to obtain an identifier and uses the identifier to direct actions of the user towards the appropriate EMR. The mobile application can further provide additional user access verification. Alerts can further be provided through the mobile application. The mobile application deletes from the mobile device all information that has been transmitted or received from the cloud-computing environment once the information is no longer used.

Abstract: A wearable ECG device includes a band having a first and a second ECG electrode, the first and the second ECG electrodes electrically connected as a common electrode. A device body is removably coupled to the band, and has a face and a display on a first side thereof, and a third ECG electrode on an opposite face thereof. A clasp is coupled to the band to secure the device around a wrist of a user, the clasp having a fourth ECG electrode, the fourth ECG electrode insulated from the band.

Abstract: The present invention provides a bio-electrode composition including: a resin containing a urethane bond in a main chain and a siloxane bond in a side chain; and an electro-conductive material, wherein the electro-conductive material is a polymer compound having one or more repeating units selected from fluorosulfonic acid salts shown by the following formulae (1)-1 and (1)-2, sulfonimide salts shown by the following formula (1)-3, and sulfonamide salts shown by the following formula (1)-4. This can form a living body contact layer for a bio-electrode that is excellent in electric conductivity and biocompatibility, light in weight, manufacturable at low cost, and free from large lowering of the electric conductivity even when it is wetted with water or dried. The present invention also provides a bio-electrode in which the living body contact layer is formed from the bio-electrode composition, and a method for manufacturing the bio-electrode.

Abstract: A system and method for cardiac activation imaging includes non-invasively or minimally invasively acquiring data about an electrical activation of a heart of a subject using at least one sensor. An activation image of the heart of the subject is reconstructed using a weighted sparse constrained reconstruction.

Abstract: An apparatus for providing arrhythmia information uses an esophageal probe having a longitudinal axis oriented in the direction of the esophagus where it is intended to be lodged, the probe comprising at least three electrode portions spaced in the longitudinal esophageal direction of the probe. The apparatus comprises a control unit, wherein the electrode portions are connected to the control unit, wherein the control unit is configured to detect potential differences between different pairs of the electrode portions. The control unit is configured to determine a repeating heart beat pattern as basis for a time resolved determination of the potential in the direction of the longitudinal axis and possibly also a perpendicular axis of the esophageal probe using compressive sensing. The apparatus is configured to provide a plot with the representation of the activation map as observed on the posterior wall or any other wall of the heart.

Abstract: An implantable medical device comprises a sensing module configured to obtain electrical signals from one or more electrodes and a control module configured to process the electrical signals from the sensing module in accordance with a tachyarrhythmia detection algorithm to monitor for a tachyarrhythmia. The control module detects initiation of a pacing train delivered by a second implantable medical device, determines a type of the detected pacing train, and modifies the tachyarrhythmia detection algorithm based on the type of the detected pacing train.

Abstract: A system for bi-hemispheric brain wave measurements including a first device and a second device, wherein at least said first device is adapted to be worn in or at a first ear of a person subject to the measurements and wherein the first and second device exchange data using at least one wireless link configured to allow first digital data at least derived from first brain wave measurements from the first device to be compared with second digital data at least derived from second brain wave measurements from the second device. The invention also provides a method for measuring a bi-hemispherical brain wave signal.

Abstract: A system and method for assessing brain function is disclosed that comprises electronically recording biologic information of a user with one or more electronics modules as the user progresses through a series of cognitive, sensory, activation, and/or stimulation tasks. The method includes extracting one or more data features from the record biologic information to obtain extracted data features. The method includes analyzing the extracted data features for each task so to develop a predictive outcome assessment of one or more brain conditions of the user, wherein predictive outcome assessment is at least one of a) an injury determination, b) a brain injury index, or c) a brain health assessment. Medical therapy is provided to the user in accordance with the predictive outcome assessment.

Abstract: An extended wear electrocardiography patch with wire interconnects is provided. The patch includes a flexible backing formed of an elongated strip of stretchable material with narrow longitudinal midsection evenly tapering inward from a distal end and a proximal end, the elongated strip adherable only at a contact surface defined on each of the ends; a pair of electrocardiographic electrodes interfaced to one or more of a set of electrode pads, each of the electrodes including an electrically conductive surface only exposed on the contact surface; a battery connected to one or more of the pads of the set via at least one flexile wire interconnect, the battery secured in place via a flexile wire; and the set of electrical contact pads included on the flexible backing and formed by a set of further flexile wires, the set configured to interface the electrodes and the battery with an electrocardiography monitor recorder.

Abstract: In one aspect, a method comprises: receiving data indicative of at least one phase image captured using a magnetic resonance imaging (MRI) device during delivery of thermal therapy by a thermal therapy applicator to a target volume within a patient's body; and processing said at least one phase image; wherein said processing said at least one phase image comprises: applying a first mask; applying phase unwrap; and applying a second mask.

Abstract: Methods and apparatus for corneal imaging and sensing are provided. Apparatus capable of utilizing single or multiple frequency emissions at terahertz (THz) wavelengths to create reflectivity maps of the cornea in either a contact or non-contact modes are also provided. Methods of obtaining data from THz imaging and sensing apparatus about the corneal tissue-aqueous humor system, including information about the corneal tissue water content (CTWC) and/or the central corneal thickness (CCT) are likewise provided. Methodologies may use multiple transfer functions (frequencies) in obtaining simultaneous data about CTWC and CCT. Methods using frequency sweeping to allow for determination of CTWC and CCT may also be utilized. Methods may also be used to assess CTWC using multiple bandwidths at the same frequency, or multiple frequencies at the same bandwidth. Methods may use data from CTWC measurements to aid in the diagnosis of various corneal and brain disorders.

Abstract: The present invention relates to a system for improving sleep effectiveness of a user.

Abstract: A processor is configured to construct a baseline impedance model (BIM) that models a portion of a heart of a subject as a collection of three-dimensional cells, each of which corresponds to a respective volume within the heart, at least some of the cells being designated as baseline-impedance cells, for each of which the BIM specifies a respective baseline impedance, to ascertain, based on a signal received via an electrical interface, an impedance between a catheter electrode, which is within the heart, and an external electrode that is externally coupled to the subject, to identify one of the baseline-impedance cells as a reference cell, to ascertain that the catheter electrode is within a threshold distance of tissue of the heart, by comparing the ascertained impedance to the baseline impedance that is specified for the reference cell, and to update a map of the tissue in response to the ascertaining.