Patents Issued in May 28, 2019
  • Patent number: 10300452
    Abstract: The present invention provides methods, compositions, and systems for distributing single polymerase molecules into array regions. In particular, the methods, compositions, and systems of the present invention result in a distribution of single polymerase molecules into array regions at a percentage that is larger than the percentage expected to be occupied under a Poisson distribution.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: May 28, 2019
    Assignee: Pacific Biosciences of California, Inc.
    Inventors: Lei Sun, Natasha Popovich, Gene Shen, Thang Pham, Stephen Turner
  • Patent number: 10300453
    Abstract: A device which can increase the rates of interfacial reactions including heterogeneous electron transfer reactions, the device comprising at least one sono(electro)chemical cell adapted to hold a thin layer of condensed fluid which is optionally adapted to participate in a heterogeneous electron transfer reaction, wherein the cell is further adapted to provide an ultrasonic transducer face to propagate sound waves into the thin layer of condensed fluid, and wherein the cell is still further adapted with an opening to provide the thin layer of condensed fluid with at least one interface which provides for reflection of the sound waves from the interface back into the thin layer of condensed fluid. The cells are configured to provide for a thin layer operation as opposed to a bulk operation. In method embodiments, ultrasound is applied to the thin layer of condensed fluid. The application of ultrasound is carried out both without cooling of the cell and without pressurization of the cell.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: May 28, 2019
    Inventors: Johna Leddy, Chester G. Duda, Jacob Lyon, William J. Leddy, III
  • Patent number: 10300454
    Abstract: A system includes a first chamber, a second chamber, an ultraviolet light source and a microwave source. The first chamber includes an inlet. The second chamber is adjacent the first chamber and includes an outlet and a waveguide. The ultraviolet light source resides within the waveguide of the second chamber. Related apparatus, systems, techniques and articles are also described.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: May 28, 2019
    Assignee: BREAKTHROUGH TECHNOLOGIES, LLC.
    Inventor: Kamal Jaffrey
  • Patent number: 10300455
    Abstract: The present invention relates to a zeolite material in the form of FAU zeolite nanocrystal aggregates, to the method for preparing said material, to the zeolite agglomerates prepared from said material with a binder, and to the uses of said material and agglomerate as adsorbents for gas-phase or liquid-phase separation operations, and particularly in methods for separating gas or liquid flows.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: May 28, 2019
    Assignee: Arkema France
    Inventors: Serge Nicolas, Guillaume Ortiz, Ludivine Bouvier, Cecile Lutz
  • Patent number: 10300456
    Abstract: A method for manufacturing activated carbon may include preparing activated carbon precursors, carbonizing the activated carbon precursors by performing a heat treatment on the carbon precursors, equalizing the activated carbon precursors carbonized in the carbonizing, by grinding the activated carbon precursors, and activating the activated carbon precursors by introducing a mixture gas including carbon dioxide and steam into the ground activated carbon precursors and performing a heat treatment on the activated carbon precursors.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: May 28, 2019
    Assignees: Hyundai Motor Company, Inha University Research and Business Foundation
    Inventors: Shin Tae Bae, Youjin Park, Soo Jin Park, Young Jung Heo
  • Patent number: 10300457
    Abstract: The present invention is directed to an absorbent material and the fibers therein, having two or more layers including an upper surface layer which has on the outer surface of the layer one or more surface area zones which are more wettable zones and adjacent thereto one or more less wettable zones, where the more wettable zones have a greater hydrophilicity than the less wettable zone. The present invention is also directed to the fibers therein, which contain polyvalent cation-containing compounds and fatty acid containing compounds. The present invention also provides for methods of treating fibers or solid materials and processes of producing the hydrophobic materials.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: May 28, 2019
    Assignee: GEORGIA-PACIFIC NONWOVENS LLC
    Inventors: Jacek K. Dutkiewicz, Stephen A. Skirius, Sonja McNeil Fields, Lynn Hung Rushing, David Jay Smith, Michael Kalmon, Ronald Timothy Moose, Ryszard Fryczkowski, Beata Fryczkowska, Monika Rom
  • Patent number: 10300458
    Abstract: To provide water-absorbing resin powder particularly useful for a sanitary article, water-absorbing resin powder containing a polyacrylic acid (salt)-based water-absorbing resin as a main component is surface-crosslinked, and satisfies (1) to (3) below: (1) a proportion of a water absorbent resin powder having a particle size of not less than 150 ?m and less than 850 ?m is not less than 90 weight %; (2) a water absorption time according to a vortex method is not more than 42 seconds; and (3) an elastic modulus index (600-500) is not less than 5500.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: May 28, 2019
    Assignee: NIPPON SHOKUBAI CO., LTD.
    Inventors: Kazushi Torii, Ryosuke Fujikawa
  • Patent number: 10300459
    Abstract: A process includes reacting a feed stream containing ethanol and optionally acetaldehyde in a dehydration reactor in the presence of a dehydration catalyst system having a Group 4 or Group 5 metal oxide and a support. The process includes obtaining a product stream containing butadiene from the dehydration reactor. Another process includes reacting a feed stream containing ethanol and optionally acetaldehyde in a dehydration reactor in the presence of a dehydration catalyst system containing a tungsten oxide supported on a zeolite or a tantalum oxide supported on a zeolite. The process includes obtaining a product stream containing butadiene from the dehydration reactor.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: May 28, 2019
    Assignee: FINA TECHNOLOGY, INC.
    Inventors: Sivadinarayana Chinta, Kaushik Gandhi
  • Patent number: 10300460
    Abstract: Methods for synthesizing a water-soluble titanium-silicon complex are disclosed herein. The titanium-silicon complex can be utilized to produce titanated solid oxide supports and titanated chromium supported catalysts. The titanated chromium supported catalysts subsequently can be used to polymerize olefins to produce, for example, ethylene based homopolymer and copolymers.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: May 28, 2019
    Assignee: Chevron Phillips Chemical Company L.P.
    Inventors: Max P. McDaniel, Kathy S. Clear, Eric D. Schwerdtfeger, Jeremy M. Praetorius
  • Patent number: 10300461
    Abstract: In order to specify a catalytic converter, especially SCR catalytic converter, with maximum catalytic activity, this catalytic converter has at least one catalytically active component and additionally at least one porous inorganic filler component having meso- or macroporosity. The organic porous filler component has a proportion of about 5 to 50% by weight. More particularly, a diatomaceous earth or a pillared clay material is used as the porous inorganic filler component.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: May 28, 2019
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Juergen Bauer, Ralf Dotzel, Joerg Walter Jodlauk, Rainer Leppelt, Joerg Werner Muench
  • Patent number: 10300462
    Abstract: A silver impregnation solution comprising: (i) silver ions, (ii) a silver concentration enhancer selected from at least one ammonium salt having an anionic component that is thermally decomposable; or at least one amino acid, or a combination thereof, (iii) at least one organic amine; and (iv) water; wherein said components (i)-(iii) are dissolved in said impregnation solution, and oxalic acid may or may not be included. The silver impregnation solution can achieve significantly higher silver concentrations, including at least or above 33, 34, or 35 wt %. Methods for producing a silver catalyst by silver impregnation of a refractory support followed by calcination are also described. The resulting silver catalysts possess high silver loadings of typically at least 17, 18, or 19 wt %.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: May 28, 2019
    Assignee: SCIENTIFIC DESIGN COMPANY, INC.
    Inventors: Lixin Cao, Andrzej Rokicki
  • Patent number: 10300463
    Abstract: Provided is a catalyst for manufacturing an unsaturated aldehyde and/or an unsaturated carboxylic acid, which is prepared by a method in which a molybdenum component raw material is composed of only an ammonium molybdate, the weight of water for dissolution is 8.5 times or less relative to the weight of molybdenum contained in the ammonium molybdate; and a bismuth component raw material is composed of only bismuth nitrate, the weight of a nitric acid aqueous solution for dissolution is 2.3 times or more relative to the weight of bismuth contained in the bismuth nitrate, and a nitric acid concentration in the nitric acid aqueous solution for dissolving the bismuth nitrate is 10% by weight or more.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: May 28, 2019
    Assignee: NIPPON KAYAKU KABUSHIKI KAISHA
    Inventors: Tomoyuki Kawamura, Motohiko Sugiyama, Ryota Hiraoka
  • Patent number: 10300464
    Abstract: Disclosed is a method for producing, among others, alkenes and/or saturated or unsaturated oxygenates and, which include at least one of an aldehyde and an acid, comprising subjecting the corresponding C3 to C5 aliphatic alcohols that are derivable from biomass, to a vapor phase process over the catalytic system in the presence of a gas mixture of oxygen, air or nitrogen and/or other suitable diluting gas. The catalyst system comprises multi-catalytic zones, in each of which the composition of the co-feed and other reaction parameter can be independently controlled.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: May 28, 2019
    Assignee: EverNu Technology, LLC
    Inventors: Manhua Lin, Wai-si Eng
  • Patent number: 10300465
    Abstract: Catalysts, catalytic forms and formulations, and catalytic methods are provided. The catalysts and catalytic forms and formulations are useful in a variety of catalytic reactions, for example, the oxidative coupling of methane. Related methods for use and manufacture of the same are also disclosed.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: May 28, 2019
    Assignee: Siluria Technologies, Inc.
    Inventors: Erik M. Freer, Wayne P. Schammel, Fabio R. Zurcher, Joel M. Cizeron, Jin Ki Hong, Anja Rumplecker, Sam Maurer, Joel Gamoras, Daniel Rosenberg, Erik C. Scher
  • Patent number: 10300466
    Abstract: The present invention relates to a process for modifying the physical and chemical properties of Faujasite Y-type zeolites (FAU), mainly used as a base material of catalyst used in the Fluid Catalytic Cracking (FCC) process, for the interest of the oil refining industry, in which the conversion of oil heavy fractions into lighter fractions, with a higher commercial value, is carried out. The process produces a modified Faujasite Y-type zeolite, with lower sodium content, as low as 75%, than that of the starting Faujasite Y-type zeolite. A mesoporous material associated with the modified Faujasite Y-type zeolite has an average pore size ranging from 2 to 100 nm, having a bimodal or multimodal pore size distribution. The proportion of modified Faujasite Y-type zeolite with respect to the meso-porous material associated to the Faujasite Y type Zeolite can be regulated through the process operation conditions.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: May 28, 2019
    Assignee: INSTITUTO MEXICANO DEL PETROLEO
    Inventors: Hector Armendariz Herrera, Maria de Lourdes Alejandra Guzman Castillo, Francisco Javier Hernandez Beltran, Patricia Perez Romo, Jaime Sanchez Valente, Jose Marie Maurice Julien Fripiat
  • Patent number: 10300467
    Abstract: A method to make a phosphorus modified zeolite can include providing a zeolite including at least one ten member ring in the structure, steaming the zeolite, mixing the zeolite with one or more binders and shaping additives, and then shaping the mixture. The method can include making a ion-exchange. The shaped mixture can be steamed. Phosphorous can be introduced on the catalyst to introduce at least 0.1 wt % of phosphorus, such as be dry impregnation or chemical vapor deposition. A metal, such as calcium, can be introduced. The catalyst can be washed, calcinated, and then steamed. The steaming severity (X) can be at least about 2. The catalyst can be steamed at a temperature above 625° C., such as a temperature ranging from 700 to 800° C. The catalyst can be used in alcohol dehydration, olefin cracking, MTO processes, and alkylation of aromatics by alcohols with olefins and/or alcohols.
    Type: Grant
    Filed: July 25, 2012
    Date of Patent: May 28, 2019
    Assignee: TOTAL RESEARCH & TECHNOLOGY FELUY
    Inventors: Nikolai Nesterenko, Delphine Minoux, Cindy Adam, Jean-Pierre Dath
  • Patent number: 10300468
    Abstract: A process for the preparation of a zeolitic material having an MWW framework structure and comprising boron and titanium, the process comprising (i) providing an aqueous synthesis mixture comprising a silica source, a boron source, a titanium source, and an MWW templating agent; (ii) heating the aqueous synthesis mixture to a temperature in the range of from 160 to 190 ° C.; (iii) subjecting the synthesis mixture (ii) to hydrothermal synthesis conditions, obtaining, in its mother liquor, a precursor of the zeolitic material; (iv) separating the precursor from its mother liquor; (v) calcining the separated precursor, obtaining the zeolitic material having an MWW framework structure and comprising boron and titanium.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: May 28, 2019
    Assignee: BASF SE
    Inventors: Andrei-Nicolae Parvulescu, Ulrich Mueller, Georg Uhl, Joaquim Henrique Teles, Dominic Riedel
  • Patent number: 10300469
    Abstract: The invention describes phospho-amino pincer-type ligands, metal complexes thereof, and catalytic methods comprising such metal complexes.
    Type: Grant
    Filed: November 26, 2014
    Date of Patent: May 28, 2019
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Kuo-Wei Huang, Chengling Pan, Yupeng Pan
  • Patent number: 10300470
    Abstract: This describes homogeneous catalysts that are recoverable from solution by being phase selective and through host-guest interactions. An example of a method includes separating a water soluble N-heterocyclic carbene homogeneous catalyst from a solution by: (a) forming a host-guest compound between the catalyst and an inclusion compound in the solution; and (b) isolating the host-guest compound from the solution.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: May 28, 2019
    Assignee: Florida State University Research Foundation, Inc.
    Inventor: Hoyong Chung
  • Patent number: 10300471
    Abstract: Using a [RuCl2(arene)]2 complex and a formate source, a directed ortho C—H insertion and aryl-aryl coupling sequence in water provides biaryl compounds useful in the preparation of biologically active molecules and intermediates. Reactions may be conducted in the ambient atmosphere. Ruthenium catalysts prepared from [RuCl2(arene)]2 and a formate source may be prepared in situ or isolated for later use.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: May 28, 2019
    Inventors: Ali Aiden Koohang, Anita Mehta
  • Patent number: 10300472
    Abstract: The present invention relates to a catalyst composition including a phosphorous-based ligand, and a hydroformylation method using the catalyst composition. More particularly, the present invention relates to a catalyst composition, which includes two different kinds of monocoordinated phosphine ligands and a transition metal catalyst, and a hydroformylation method using the catalyst composition. In accordance with the present invention, a catalyst composition lowering a selection ratio of normal aldehyde to iso aldehyde (n/i ratio), which are generated during hydroformylation of an olefinic compound, and exhibiting superior catalytic activity and stability, and a method of hydroformylating an olefinic compound using the catalyst composition are provided.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: May 28, 2019
    Assignee: LG CHEM, LTD.
    Inventors: Min Ji Choi, Mi Young Kim, Sung Shik Eom, Dong Hyun Ko, Da Won Jung, Tae Yun Kim
  • Patent number: 10300473
    Abstract: The invention concerns a catalytic composition comprising: at least one nickel precursor with an oxidation number of (+II) containing a phosphine ligand complexed with nickel, at least one Lewis base, and at least one activating agent selected from the group formed by chlorinated and brominated hydrocarbylaluminium compounds, used alone or as a mixture, in a manner such that the molar ratio of the ensemble of the Lewis base and phosphine ligand complexed with the nickel of the composition to the nickel is in the range 5 to 30. The invention also concerns the use of said catalytic composition.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: May 28, 2019
    Assignee: IFP Energies Nouvelles
    Inventors: Pierre-Alain Breuil, Olivia Chaumet-Martin
  • Patent number: 10300474
    Abstract: A method for producing one or more hydrocarbon compounds from at least one of 2,3-butanediol, acetoin, and ethanol, the method comprising contacting said at least one of 2,3-butanediol, acetoin, and ethanol with a catalyst at a temperature of at least 100° C. and up to 500° C. to result in said 2,3-butanediol, acetoin, and/or ethanol being converted to said one or more hydrocarbon compounds, wherein said catalyst is either: (i) a catalyst comprising nanoparticles composed of (a) a first metal oxide selected from the group consisting of zirconium oxide, cerium oxide, titanium oxide, and lanthanum oxide, and (b) a main group metal oxide; or (ii) a catalyst comprising a zeolite loaded with at least one metal selected from the group consisting of copper, silver, nickel, palladium, platinum, rhodium, and ruthenium in an amount of 1-30 wt % by weight of the zeolite.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: May 28, 2019
    Assignee: UT-Battelle, LLC
    Inventor: Zhenglong Li
  • Patent number: 10300475
    Abstract: A circumferential coating material which is coated on a circumferential surface of a honeycomb structure monolithically formed by extrusion, to form a circumferential coating layer, the circumferential coating material containing fused silica in a range of 20 to 75 mass %, containing a color developing agent in a range of 5 to 50 mass %, containing colloidal silica in a range of 5 to 30 mass %, and further containing a silicon based water repellent agent in a range of 1 to 10 mass % to a total mass of the fused silica, the color developing agent, and the colloidal silica.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: May 28, 2019
    Assignee: NGK Insulators, Ltd.
    Inventors: Shuji Ueda, Shungo Nagai, Takayoshi Shibayama, Yoshihiro Sato, Makoto Murai, Kojiro Hayashi
  • Patent number: 10300476
    Abstract: Methods for regenerating a spent catalyst in a metal reactor are disclosed. Such methods may employ a step of chlorinating the spent catalyst, followed by decoking the chlorinated spent catalyst, and then fluorinating the de-coked catalyst.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: May 28, 2019
    Assignee: Chevron Phillips Chemical Company LP
    Inventor: Gabriela D. Alvez-Manoli
  • Patent number: 10300477
    Abstract: The present disclosure herein relates to a terminally-crosslinked methyl morpholinium-functionalized block copolymer, and an anion exchange membrane using the same, and more particularly, to a terminally-crosslinked block copolymer which has a novel structure, and in which, in a poly(arylene ether sulfone) multiblock copolymer (MM-PES) having methyl morpholinium as a conducting group, an azide compound may be used as a crosslinking agent so that crosslinking only occurs at ends of the polymer chains (xMM-PES), thereby minimizing conductivity loss, significantly increasing mechanical and chemical stability, attaining additional conductivity resulting from the three-dimensional structure of morpholinium, and reducing water uptake while enhancing water retention capacity, uses thereof as an alkaline fuel cell anion exchange membrane (AEM), and a method for conveniently preparing the same through simple heat-treatment.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: May 28, 2019
    Assignee: INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: Tae Hyun Kim, So Hyun Kwon
  • Patent number: 10300478
    Abstract: The present invention relates to a bipolar ion exchange sheet and a manufacturing method therefor, the bipolar ion exchange sheet comprising: a cation exchange film comprising a cation adsorption sheet and a cation exchange coating layer formed on one side of the cation adsorption sheet; and an anion exchange film comprising an anion adsorption sheet and an anion exchange coating layer formed on one side of the anion adsorption sheet, wherein the cation exchange film and the anion exchange film are bonded so that the cation exchange coating layer and the anion exchange coating layer face each other.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: May 28, 2019
    Assignee: Coway co., Ltd
    Inventors: Sung-Min Moon, Jun-Young Lee, Sun-Beom Choi, Sang-Hyeon Kang, Kyung-Seok Kang, Won-Keun Son
  • Patent number: 10300479
    Abstract: The present disclosure provides apparatuses, systems, and methods involving a spotter apparatus for depositing a substance from a carrier fluid onto a deposition surface in an ordered array. The spotter apparatus includes a loading surface, including a first well and a second well, and a different outlet surface, including a first opening and a second opening, where a first microconduit fluidly couples the first well with the first opening and a second microconduit fluidly couples the second well with the second opening. An overlay is sealed to the outlet surface and penetrated by a deposition channel that is situated to communicate carrier fluid among the first opening, the second opening, and the deposition surface when the overlay is pressed against the deposition surface.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 28, 2019
    Assignee: Carterra, Inc.
    Inventors: Bruce Kent Gale, Adam Miles, Joshua Wayne Eckman, Sriram Natarajan, Jim Smith, Mark Eddings
  • Patent number: 10300480
    Abstract: A pipetting device (100) for an apparatus (164) for processing a sample or reagent is disclosed. The pipetting device (100) comprises a coupling mechanism (102), wherein the coupling mechanism (102) comprises at least a first coupling unit (104) adapted to be coupled to a first pipetting tip and a second coupling unit (106) adapted to be coupled to a second pipetting tip, and a tilt mechanism (112) for moving the first coupling unit (104) between an untilted position, in which the first coupling unit (104) and the second coupling unit (106) are arranged parallel to one another, and a tilted position, in which the first coupling unit (104) is tilted relative to the second coupling unit (106).
    Type: Grant
    Filed: October 12, 2016
    Date of Patent: May 28, 2019
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Hans-Rudolf Bachmann, Rolf Schneebeli
  • Patent number: 10300481
    Abstract: A centrifuge tube assembly includes an elongate tubular receptacle having upper and lower ends and a side wall that extends between the ends. A cap attached to the receptacle carries a common inlet/outlet port formed therethrough for communication with an interior chamber of the tubular receptacle. A liquid impermeable piston is longitudinally movable through the receptacle chamber and sealably interengages an interior wall of the receptacle. The piston separates upper and lower regions of the chamber, which respectively communicate with the inlet/outlet port and a pressure neutralizing vent. Biological products are introduced into and aspirated from the receptacle through the inlet/outlet port.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 28, 2019
    Inventor: Patrick Pennie
  • Patent number: 10300482
    Abstract: An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: May 28, 2019
    Assignee: AKONNI BIOSYSTEMS, INC.
    Inventors: Christopher G. Cooney, Phillip Belgrader, Arial Bueno, Steve Garber, Nitu Harshendu Thakore, Peter Qiang Qu
  • Patent number: 10300483
    Abstract: A multi-index detection microfluidic chip is provided. A bottom plate (1) and a cover plate (2) that matches the bottom plate (1) and seals it are provided in the microfluidic chip. The center of the microfluidic chip has a through-hole (3). The bottom plate (1) has one or more wave-shaped main channel(s) (4), one end of each of the main channel (4) connected to a sample injection hole (9) on the bottom plate (1), and the other end connected to an exhaust hole (10) on the bottom plate (1). The valley on the main channel (1) is distal to the through-hole (3), and the peak is proximal to the through-hole (3). Each valley of the main channel (1) is connected to a reaction chamber (6) by a linking channel (5). The linking channel (5) comprises one or more buffering chambers (7). The microfluidic chip can be used in detection by fluorescence, turbidity, color, detection equipment, and/or direct observation by the naked eyes. The detection is real-time as the reaction occurs or after the reaction.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: May 28, 2019
    Assignee: Capitalbio Technology Corporation
    Inventors: Lei Wang, Guohao Zhang, Xinying Zhou, Juan Xin, Yao Zhang, Mingxian Lin, Guoliang Huang, Can Wang, Wanli Xing, Jing Cheng
  • Patent number: 10300484
    Abstract: A handheld system includes a reference pressure source configured to generate a reference pressure. The handheld system also includes a primary pressure source coupled to the reference pressure source. The primary pressure source is configured to generate a primary pressure in a primary pressure range. The primary pressure is less than the reference pressure, and the primary pressure is induced by the reference pressure source. The handheld system also includes a secondary pressure source coupled to the primary pressure source. The secondary pressure source is configured to generate a secondary pressure in a secondary pressure range. The secondary pressure is less than the primary pressure, and the secondary pressure is induced by the primary pressure source.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: May 28, 2019
    Assignee: THE GEORGE WASHINGTON UNIVERSITY
    Inventors: Zhenyu Li, Baichen Li
  • Patent number: 10300485
    Abstract: Methods and apparatuses for performing a nanoarray-in-microarray assay is provided, which can be used to estimate a protein concentration in a sample solution. A plurality of nanodots are fabricated on a surface having at least one affinity binder. One or more microspots are superimposed over the nanodots on predetermined regions of the surface, each of the microspots comprising at least one antibody. An assay process is performed on the surface, and the surface is imaged to acquire optical images of the nanodots within each microspot. Image analysis algorithms are the performed on the optical images to identify bindings on individual ones of the plurality of nanodots.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: May 28, 2019
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: David Juncker, Gina Zhou, Sebastien Bergeron
  • Patent number: 10300486
    Abstract: A microfluidic system is presented that includes a cartridge and a container. The cartridge includes a plurality of microfluidic channels coupled to one or more chambers. The container holds dry chemicals and includes a housing with a first opening and a second opening smaller than the first opening. The container is designed to be inserted into an opening of the cartridge, such that the container is independently secured within the opening. The insertion of the container allows for the container to be fluidically coupled with a microfluidic channel of the plurality of microfluidic channels via the second opening.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: May 28, 2019
    Assignee: STAT-DIAGNOSTICA & INNOVATION, S.L.
    Inventors: Holger Engel, Jordi Carrera Fabra
  • Patent number: 10300487
    Abstract: A holder for a pipette having a bulb is disclosed. In use, the bulb of the pipette is inserted into the holder and the user can hold the holder rather than the bulb to use the pipette. In this way, the holder enables the pipette to be held without any application of force from the user directly on the bulb. This enables the user to accurately draw a desired amount of liquid into the pipette. The holder comprises an aperture through which the bulb is accessible. The user can dispense liquid from the pipette by actuating the bulb through the aperture.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: May 28, 2019
    Assignee: Biosurfit, S.A.
    Inventors: Nuno Alexandre Esteves Reis, Miguel João Marques Barreiros, Tania Moura Pires de Andrade Tenreiro
  • Patent number: 10300488
    Abstract: Provided herein are anti-static pipette trays that reduce the amount of static charge accumulated on or in pipette tips and allow for discharge of any accumulated static charge.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: May 28, 2019
    Assignee: Biotix, Inc.
    Inventors: Arta Motadel, Scott Edward Curry
  • Patent number: 10300489
    Abstract: A blade element (11) for a refiner (10) for refining fibrous material has a blade element body (12) and blade bars (13, 13a, 13b) and blade grooves (14, 14a, 14b) therebetween. Bottoms of the blade grooves (14, 14a, 14b) have, in the longitudinal direction (LD) of the blade grooves, a variable depth profile comprising alternating high points (14a?, 14b?) and low points (14a?, 14b?) so that there is a phase shift (X2) between the high points (14a?, 14b?) and the low points (14a?, 14b?) of the variable depth profiles of the bottoms of the adjacent blade grooves (14a, 14b). Also, a refiner (10) for refining fibrous material and a method for manufacturing the blade element (11) for the refiner (1).
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: May 28, 2019
    Assignee: Valmet Technologies, Inc.
    Inventors: Marko Loijas, Timo Könönen, Matti Kaarineva
  • Patent number: 10300490
    Abstract: A rotary mill for grinding recycled glass materials into particles has a housing defining an impact chamber with a rotor in the chamber at the bottom of an inclined guide wall underneath the feed opening. The rotor has a plurality of axially extending, angularly spaced massive impact hammers so that the impact hammers impact and deflect the solid materials onto a plurality of shatter bars located at the peripheral wall. Each of the impact hammers has a leading blade element of a hardened steel which has a front face inclined relative to a bottom portion of the guide surface so that an outer edge of the front face is angularly advanced relative to an inner edge thereof.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: May 28, 2019
    Assignee: Patent Applied Technology
    Inventor: David Langtry
  • Patent number: 10300491
    Abstract: An improved hammer mill hammer constructed by forming a groove in an edge of the grinding end of a hammer for receiving hard facing material and placing hard facing in the groove.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: May 28, 2019
    Inventor: Chad J. Plumb
  • Patent number: 10300492
    Abstract: Apparatus and system of components to mechanically exfoliate particulate materials using a multi-axis approach to deliver predetermined forces to a particulate material, including containers to hold particulate material and media, also including media, and, the associated parameters for operating such equipment along with methods and compositions provided by the apparatus and methods.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: May 28, 2019
    Assignee: XG SCIENCES, INC.
    Inventors: Scott L. Murray, Jim L. Peyton, Korey Morris
  • Patent number: 10300493
    Abstract: The invention relates to a shell plate, to a method for making a shell plate and to a grinding mill for ore grinding. The shell plate is mountable to a shell of a grinding mill for grinding ore and includes a shell plate body having a first portion including a fixing surface for fixing the shell plate body to the shell, and a second portion having a wear surface facing toward an interior of the grinding mill. The first portion and the second portion form a continuous shell plate body, and the second portion includes polyurethane such that the wear surface is made of polyurethane.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: May 28, 2019
    Assignee: OUTOTEC (FINLAND) OY
    Inventor: Kari Lauermaa
  • Patent number: 10300494
    Abstract: A process for trichome separation from plant matter deploys water slurry agitation and/or dry sieving to produce a mixture of solid trichomes and similar sized plant debris. The plant debris in each separate fraction is then removed by gravity filtration in a dense inert liquid, which is preferably a salt or brine solution. The desirable trichomes or trichome glands float on the dense liquid, while the undesirable vegetative matter sinks to the bottom of the brine containing vessel. The trichomes are readily removed and washed before further processing.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: May 28, 2019
    Assignee: TETRAGROW INC.
    Inventor: David M Cilia
  • Patent number: 10300495
    Abstract: An apparatus and method for removing an underflow stream is provided suitable for removing an underflow stream from a separator, such as a mineral particle separator. In one aspect, the separator can include a discharge outlet for discharging the underflow stream, and the apparatus can include a source of pressurised fluid, a first conduit for fluidly connecting the pressurised fluid source to the discharge outlet such that the pressurized fluid is directed to impede the flow of the underflow stream in the first conduit, thereby creating a fluidisation zone, and a second conduit fluidly connected to the first conduit so that material from the fluidisation zone flows into the second conduit for removal from the apparatus.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: May 28, 2019
    Assignee: NEWCASTLE INNOVATION LIMITED
    Inventor: Kevin Patrick Galvin
  • Patent number: 10300496
    Abstract: The present invention relates to core-shell-particles, wherein the core comprises at least one metal, or a compound thereof, or a mixture of at least one metal or a compound thereof and at least one semimetal or a compound thereof, and the shell comprises at least one silicon comprising polymer, to a process for the preparation of these core-shell-particles, to the use of these core-shell-particles in an agglomeration-deagglomeration process, in particular in chemical, physical or biological test methods or separation processes, decontamination processes, water purification, recycling of electrical/electronic scrap or gravity separation, and to a process for separating at least one first material from a mixture comprising this at least one first material and at least one second material.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: May 28, 2019
    Assignees: BASF SE, BASF Corporation
    Inventors: Florian Blasberg, Andreas Luz, Igor Shishkov, David J. Gilbert, Wolfgang Rohde
  • Patent number: 10300497
    Abstract: A magnetic separator includes a housing defining a product flow path through which material may pass. The magnetic separator further includes a drawer moveable between a first position and a second position and at least one magnet operatively connected to the drawer. The at least one magnet is positioned within the product flow path in the first position of the drawer. The at least one magnet is withdrawn from the flow path when in the second position.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: May 28, 2019
    Assignee: Magnetic Products, Inc.
    Inventor: Ronald Kwasniewicz
  • Patent number: 10300498
    Abstract: A seal for a centrifuge for preventing material from leaking out of an effluent portion into a drive portion where the seal is disposed between a basket carrier and a drive portion, and the basket carrier is disposed between the effluent portion and the drive portion. The seal can also be disposed on a stiffener, the stiffener disposed between the basket carrier and the drive portion. A sealing arrangement for a centrifuge including a contact seal and a labyrinth disc, for preventing liquid from leaking out of an effluent portion into a product discharge outlet and for preventing material from entering into the effluent portion through the product discharge outlet. Also provided is a centrifuge incorporating the seal and/or the sealing arrangement.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: May 28, 2019
    Assignee: FLSmidth A/S
    Inventors: Mathew Walker, Michael J. Gardiner, Tony Elliott
  • Patent number: 10300499
    Abstract: A centrifuge having a driveshaft that has an end section that tapers toward the central axis of the driveshaft. A rotor is removably mounted on the driveshaft such that the rotor may be axially removed in a removal direction. A bearing surface of a locking element of the rotor is connected to the driveshaft and holds the rotor against removal. A quick-action closure is integrated into the rotor and prevents removal of the driveshaft and the rotor in the removal direction. The end section of the driveshaft extends through an opening in the rotor where it is partially surrounded by multiple locking elements of the rotor for fixing the rotor and the driveshaft together. The locking elements include bearing surfaces engaging the end section and support surfaces engaging the rotor. The quick-action closure has force-transmitting elements which connect the locking elements to a handle permitting locking and/or unlocking the quick-action closure by a respective movement of the handle.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: May 28, 2019
    Assignee: ANDREAS HETTICH GMBH & CO. KG
    Inventors: Matthias Hornek, Frank Thuringer, Andreas Holderle, Klaus-Gunter Eberle
  • Patent number: 10300501
    Abstract: A polymer activation assembly is provided for separating monomer from the oil in which it is suspended in a polymer forming suspension and mixing the monomer with water supplied from another stream. The supply water is supplied through a primary fluid channel extending through the activation assembly and which transitions to a relatively wide rectangular activation channel. A secondary fluid inlet is formed in a side of the activation assembly for injection of the polymer forming suspension therein. A nozzle section of the secondary fluid inlet is formed between an initial section of the inlet and the activation channel. The nozzle section is generally rectangular in cross section and relatively shallow. The distal end of the nozzle section has a width that approximates the width of the activation channel. The nozzle section angles at an acute angle toward the outlet.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: May 28, 2019
    Assignee: Velocity Dynamics, LLC
    Inventors: Ryan G. Morerod, Scott Leakey
  • Patent number: 10300502
    Abstract: [Object] To provide a pump dispenser which allows accurate determination of a direction of spraying of liquid without a nozzle part moving toward a higher or lower position and, furthermore, whose trigger is excellent in operability.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 28, 2019
    Assignee: CANYON CORPORATION
    Inventors: Tetsuya Tada, Mitsuaki Shaduki