Patents Issued in June 25, 2019
  • Patent number: 10328220
    Abstract: A bi-directional gas flow generation system (10), the system comprising: (a) a pressure generator (14) comprising an inlet (40) and an outlet (42), (b) a flow member (16) comprising an outlet port (50), an inlet port (52), a respiratory circuit port (54) and a flow path (60), (c) a first valve (18), (d) a second valve (20), and (e) a processor (24) configured to selectively control the first valve and the second valve to operate in (i) a first mode in which gas flows from the flow member inlet port (52) to the respiratory circuit port (54), thereby creating a positive pressure at the respiratory circuit port (54) to insufflate the subject; and (ii) a second mode in which gas flows from the respiratory circuit port (54) to the flow member outlet port (50), thereby facilitating gas flow out from the airway of the subject to exsufflate the subject.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: June 25, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Kenneth E. Cole, Jr.
  • Patent number: 10328221
    Abstract: An anesthetic breathing apparatus has a processing unit, a breathing circuit for providing an inspiratory patient gas mixture of re-breathed gas and/or fresh gas to a patient fluidly connected to the breathing circuit, and a fresh gas supply controllable by the processing unit for supplying a flow of the fresh gas to the breathing circuit in a composition including oxygen and at least one anesthetic agent (AA). A user interface includes a first user input element for receiving operator input for an anesthetic target value including an end expiratory concentration of the AA (EtAA) target value and/or an end expiratory minimum alveolar concentration (EtMAC) target value of an end expiratory MAC value of the patient, and a second user input element for receiving operator input for a desired control profile for the fresh gas supply for obtaining at least the anesthetic target value.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: June 25, 2019
    Assignee: Maquet Critical Care AB
    Inventors: Tom Pessala, Mari Andersson, Bengt Johansson, Stig Andersson, Mattias Rodehed
  • Patent number: 10328222
    Abstract: A vent device for a respiratory device, comprising one or a plurality of vents configured with a variable aperture size for communicating a flow of breathable gas. Said vent device being configured so that the cross section profile exposed to the flow of breathable gas communicating through the vent does not change as the aperture size changes. A vent device may comprise of a plurality of the said vents, wherein the aperture size of each vent may be controlled independently or together, and may be controlled according to one or more input signals from one or more sensors. Examples of suitable input signals include flow, pressure, noise, accelerometer outputs, orientation of a patient or presence of any obstructions. A patient interface or a patient conduit may comprise the vent device, or the vent device may be configured to connect with a patient interface or a patient conduit.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: June 25, 2019
    Assignee: ResMed Pty Ltd
    Inventor: Roger Mervyn Lloyd Foote
  • Patent number: 10328223
    Abstract: A recovery and collection assembly for an atomized material inhalation device is provided. The recovery and collection assembly includes an outer tubular housing and an input tube. The outer tubular housing includes a sidewall defining an outer chamber, an upper end piece attached to an upper end of the sidewall, and a lower end piece attached to a lower end of the sidewall. The lower end piece has at least one air flow opening allowing fluid communication between an interior of the outer chamber and an atmosphere surrounding the outer tubular housing. The input tube extends through the lower end piece and has a first end in fluid communication with the atomized material inhalation device. The input tube also has a second end disposed in an upper half of the outer chamber and in fluid communication with the outer chamber and defines an inner chamber.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: June 25, 2019
    Inventors: Lloyd Courtney, Ann Louise Yant
  • Patent number: 10328224
    Abstract: A cleaning catheter includes an inflatable element expandable into contact with an inner surface of a ventilation tube. An input module includes a flow regulator, which is shaped so as to define a suction port coupleable in fluid communication with a suction source, and a fluid port coupled in fluid communication with a pressurized fluid source. A mechanical user control element is configured to mechanically and non-electrically set at least base and inflation/suction activation states of the flow regulator. When in the inflation/suction activation state, the flow regulator effects fluid communication between the suction port and a distal suction orifice, and effects inflation of the inflatable element by fluid communication between the fluid port and the inflatable element via a fluid-delivery lumen. The mechanical user control element includes one or more user-interface elements, a single one of which is arranged to set the flow regulator in the inflation/suction activation state.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: June 25, 2019
    Assignee: TELEFLEX LIFE SCIENCES UNLIMITED COMPANY
    Inventors: Oron Zachar, Elad Einav, Gil Yigal
  • Patent number: 10328225
    Abstract: A dental appliance apparatus is disclosed herein. In various aspects, the dental appliance may include a body removably attachable to one or more teeth selected from premolars and molars, and a flange extending forth from lingual portions of the body to contact a tongue at one or more locations proximate the premolars and the molars in order to cause a contraction of the genioglossus that positions the tongue anteriorly and downward toward the mandible by stimulation of the hypoglossal nerve. The dental appliance may include a connector connected to the body, and the connector may pass about buccal-labial sides of the anterior teeth. A bumper may be included on a labial side of the connector, and the bumper may contact the lips to promote pursed lips breathing. An anterior flange may extend lingually from the connector to stimulate the hypoglossal nerve proximate a tip of the tongue in order to cause contraction of the genioglossus to position the tongue anteriorly and downward toward the mandible.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: June 25, 2019
    Assignee: GARNER GENIOTHRUST LLC
    Inventor: Dena P. Garner
  • Patent number: 10328226
    Abstract: A patient interface has a single loop headstrap and a mask for covering at least the nostrils of the user. The single loop headstrap extends from the mask at either end. A short length of supple conduit is coupled to the mask by a swivel or ball joint to allow rotation of the conduit relative to the mask through different angles and orientations.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: June 25, 2019
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Olivia Marie Allan, Arvin San Jose Gardiola, Lewis George Gradon, Wen Dong Huang, Alastair Edwin McAuley, Mark Arvind McLaren, Craig Robert Prentice, Andrew Paul Maxwell Salmon, Silas Sao Jin Siew
  • Patent number: 10328227
    Abstract: A tracheal tube includes an inner cannula and an outer cannula that are connected with a threaded connection able to swivel, and wherein the inner cannula is also connected to an elbow adaptor through a Bayonet Neill-Concelman (BNC) connection. Both the threaded and the BNC connects provide more secure connections of the corresponding components and are able to withstand greater amounts of force exerted on them without becoming detached from each other. The elbow adapter may further be coupled to a pressure release valve that will alleviate pressure buildup within the tracheal tube.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: June 25, 2019
    Assignee: Smart Bridge Medical, Inc.
    Inventors: Kay L. Fuller, Lisa M. Carver, Matthew T. Hill, Michael M. Hotta, Laura G. Kruger, Alexander C. Waselewski
  • Patent number: 10328228
    Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: June 25, 2019
    Assignee: Third Pole, Inc.
    Inventors: David G. Zapol, Gregory W. Hall, Wolfgang Scholz, Benjamin Apollonio, Frank Heirtzler
  • Patent number: 10328229
    Abstract: An adapter includes a housing having an inlet port defining a flow path and an outlet port. An interior wall has an inner surface defining an interior passageway communicating with the outlet port and an exterior surface defining an exterior passageway communicating with the inlet port. The interior wall defines a mouth communicating between the interior and the exterior passageways. The interior wall is positioned transverse to the flow path of the inlet port. A medicament delivery port opens into the mouth. A valve is moveable between a closed position, wherein the valve closes the medicament delivery port, and an open position, wherein the medicament delivery port is open. A ventilator circuit and method of delivering a medicament are also provided.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: June 25, 2019
    Assignee: TRUDELL MEDICAL INTERNATIONAL
    Inventors: Neritan Alizoti, James Schmidt
  • Patent number: 10328230
    Abstract: A vaporizer for delivery of a volatile medium to a gas flow, the vaporizer comprising: a gas delivery unit (3) which receives a flow of gas and provides a flow of gas containing a metered amount of a vaporized medium; a reservoir unit (5) which contains a volatile medium and maintains a supply of the vaporized medium, wherein the reservoir unit is selectively fluidly connected to the gas delivery unit; a gas sensing unit (7) for sensing a flow rate and/or composition of the gas flow; a vaporized medium sensing unit (9) for sensing a flow rate of the vaporized medium; a manifold (10) which includes flow paths for the vaporized medium and fluidly connects the reservoir unit and the vaporized medium sensing unit; and a control unit (11) for controlling a flow rate of the gas flow and an amount of the vaporized medium which is metered into the gas flow.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: June 25, 2019
    Assignee: Penlon Limited
    Inventors: Cliff Kersey, James Montgomery, Iain Revell, David Martyn White, Brian Jones
  • Patent number: 10328231
    Abstract: Described are methods and devices for therapeutic or medical gas delivery that utilize at least one proportional control valve and at least one binary control valve. The proportional control valve may be in series with the binary control valve to provide a valve combination capable of pulsing therapeutic gas at different flow rates, depending on the setting of the proportional control valve. Alternatively, the proportional control valve and binary control valve may be in parallel flow paths.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: June 25, 2019
    Assignee: Mallinckrodt Hospital Products IP Limited
    Inventors: Jaron M. Acker, Thomas Kohlmann, Craig R. Tolmie
  • Patent number: 10328232
    Abstract: Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: June 25, 2019
    Assignee: Silk Road Medical, Inc.
    Inventor: David W. Chang
  • Patent number: 10328233
    Abstract: An apparatus for stimulating neurons that includes a stimulation unit for applying pulse-like tones, a measuring unit for picking up measurement signals that render neural activity by the stimulated neurons, a control unit. The control unit applies a first pulse train having varied pitch, takes the measurement signals picked up in response to the first pulse train to select a first pitch range or pitch in which there is phase synchronization between the pulse train and the neural activity, actuates the stimulation unit to apply two phase-shifted second pulse trains, the pitch of the pulse trains being varied in opposite directions and a pitch starting value of the second pulse trains based on the first pitch range or pitch that is used to select a second pitch range or pitch resulting in minimum amplitude of the neural activity.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: June 25, 2019
    Assignee: FORSCHUNGSZENTRUM JUELICH GMBH
    Inventor: Peter Alexander Tass
  • Patent number: 10328234
    Abstract: The present disclosure pertains to a system for enhancing knowledge consolidation in a subject during sleep. New declarative memories may be better consolidated by presenting sensory stimuli during slow wave sleep that correspond to sensory stimuli presented during prior wakeful learning. The sensory stimuli may include odors, sounds, visual stimulation, touches, tastes, and/or other types of sensory stimuli. The system is configured to provide a prompt sensory stimulus during slow wave sleep that corresponds to a wakeful stimulus provided during wakeful learning. The prompt sensory stimulus may prompt enhanced knowledge consolidation in the subject. In some embodiments, the system may comprise one or more of a slow wave sleep inducer, a sensory stimulator, a sensor, a processor, electronic storage, a user interface, and/or other components.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: June 25, 2019
    Assignees: Koninklijke Philips N.V., Wisconsin Alumni Research Foundation
    Inventors: Gary Nelson Garcia Molina, Michele Bellesi, Giulio Tononi, Joanne Henriëtte Desirée Monique Westerink
  • Patent number: 10328235
    Abstract: A system and method that provides controlled bilateral stimulation to a patient in response to physiological feedback to initiate and/or accelerate the onset of sleep and to maintain the sleep state after the onset of sleep. The system induces bilateral stimulation through stimulation modules that are coupled to opposite lateral sides of the patient's body. The stimulation modules stimulate the patient's body bilaterally through a sequence of stimulations that alternate from one side of the patient's body to the other with a pause between each successive stimulation. The system controls the duration of the stimulations, the intensity of the stimulations and the period of time between successive stimulations in response to feedback from physiological sensors. The sensors are coupled to the patient and provide physiological information which initiates or terminates the bilateral stimulations, and/or modifies the characteristics of the stimulations.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: June 25, 2019
    Assignee: Insomnisolv, Inc.
    Inventor: Peter Kelley
  • Patent number: 10328236
    Abstract: Visual and auditory stimuli are provided to a patient to treat various neurological disorders or conditions and/or to provide improved mental or physical performance. The visual and auditory stimuli are provided by a wearable headset or sleep mask that may be comfortably worn by a user, such as in bed to induce sleep. The wearable headset or sleep mask is operated by a personal computing device of the user, such as smartphone, having downloaded and active thereon a control application or app for the therapy. The wearable headset or sleep mask also concurrently provides tactile stimuli, and the tactile stimulus is provided from bone conduction transducers that concurrently provides the auditory stimuli.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: June 25, 2019
    Assignee: SANA HEALTH, INC.
    Inventor: Richard Hanbury
  • Patent number: 10328237
    Abstract: A ready to use catheter assembly comprises a catheter package with an opening, a catheter with a shaft arranged in the catheter package so a distal end of the catheter lies in the region of the opening, and a protective sleeve which partly covers the catheter shaft, a first end of the protective sleeve fixed to the distal end of the catheter. A method for producing a ready to use catheter assembly and a ready to use catheter assembly which further reduces the risk of an accidental contamination of a catheter when pulling it out of the catheter package prior to the insertion into the urethra of a user are provided. The opening has a defined maximum opening length, a second end of the protective sleeve is releasably connected which the catheter package near the maximum opening length of the opening and the protective sleeve is in a retracted state.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: June 25, 2019
    Assignee: Teleflex Life Sciences Unlimited Company
    Inventors: Ronald John Kelly, Alan Fitzgerald, Morgan Tierney, Volkmar Schulz, Bernhard Hiesch
  • Patent number: 10328238
    Abstract: In a catheter system and method for controlling such a system, an elongate hollow shaft has a proximal end connected to a handle and a distal end remote from the handle. A working component is carried by the shaft and has at least one characteristic that is adjustable. An actuator is rotatably mounted on the handle for selectively adjusting at least one characteristic of the working component. A control line extends at least in part within the shaft. The control line operatively couples the actuator with the working component such that rotation of the actuator relative to the handle effects linear translation of the control line to adjust the at least one characteristic of the working component.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: June 25, 2019
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Russell D. Terwey, James Paul Goodman, Kevin Gin Park
  • Patent number: 10328239
    Abstract: A catheter insertion device and method for insertion. The catheter insertion device can include a housing, a needle attached to a needle carrier, a catheter including a catheter shaft attached to a catheter hub, and a guidewire. The guidewire can include a coil tip positioned in a lumen of the needle. The method for insertion can include inserting a distal end of the needle and the catheter shaft into a blood vessel of a patient, advancing the coil tip out of the needle lumen and into the blood vessel, advancing the catheter over the guidewire, and withdrawing the guidewire and the needle from the catheter. The coil tip can include a straightened configuration and a coiled configuration. The coil tip can transition from the straightened configuration in the needle lumen to the coiled configuration in the blood vessel.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 25, 2019
    Assignee: Vascular Pathways, Inc.
    Inventor: Amir Belson
  • Patent number: 10328240
    Abstract: An introducer sheath assembly (10) having a sheath tube (12), a hub (16), a valve (30) and a valve-retaining cap (50) on the proximal end of the hub. The cap (50) is so secured to the hub (16) as to have a closed, locked position and also an open position permitting access to the interior of the hub and the valve (30) while the cap (50) remains secured to the hub (16).
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: June 25, 2019
    Assignee: Medical Components, Inc.
    Inventors: Mahase Nardeo, William J. McCreight
  • Patent number: 10328241
    Abstract: An instrument for endoscopic applications has a first end portion and a second end portion opposing the first end portion. An intermediate cylindrical member of the instrument has a handling end portion with a flexible portion located at the first end portion and actuating means located at the second end portion. The actuating means has a first cylindrical part. The handling end portion has a second cylindrical part connected to the actuating means by longitudinal elements for transferring a movement of the actuating means to a bending of the handling end portion. The longitudinal elements are separated from one another by longitudinal slits defined in the intermediate cylindrical member. Each of the longitudinal elements is composed of a strip, adjacent strips being separated by a gap. A plate is arranged to move in a longitudinal direction of the gap but has a circumferential width filling a width of the gap.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: June 25, 2019
    Assignee: Fortimedix Surgical B.V.
    Inventor: Marcel Antonius Elisabeth Verbeek
  • Patent number: 10328242
    Abstract: A conduit management device and method for quickly and easily securing a conduit and reducing the risk of conduit disruption is disclosed. A selectively securable cleat is arranged for selective encirclement and securement of at least a portion of a conduit by wrapping the conduit around the cleat. An embodiment is disclosed having an elongate cleat that is fixed to the patient apparatus at a first location of the cleat spaced apart from releasably securable locations proximate first and second ends of the cleat such that the fixation point at the first location forms the fixed base of the cleat.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: June 25, 2019
    Assignee: REDpoint International Inc.
    Inventors: Charles E. Nokes, Jr., Ronald C. Ames
  • Patent number: 10328243
    Abstract: An improved system and method for placing implantable medical devices (IMDs) such as leads within the coronary sinus and branch veins is disclosed. In one embodiment, a slittable delivery sheath and a method of using the sheath are provided. The sheath includes a slittable hub, and a substantially straight body defining an inner lumen. The body comprises a shaft section and a distal section that is distal to, and softer than, the shaft section. A slittable braid extends adjacent to at least a portion of one of the shaft section and the distal section. In one embodiment of the invention, the sheath further includes a transition section that is distal to the shaft section, and proximal to the distal section. The transition section is softer than the shaft section, but stiffer than the distal section.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: June 25, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Stanten C Spear, James F Kelley, Kenneth C Gardeski, Mohmoud K Seraj, Eric K. Y. Chan
  • Patent number: 10328244
    Abstract: This disclosure relates generally to systems and methods for occluding vessels of the heart and inducing cardioplegic arrest to facilitate the performance of cardiac procedures. An aortic occlusion and perfusion device includes an expandable member configured to expand within the aorta to secure the device within the aorta, and a catheter extending proximally from the expandable member and in fluid communication with the expandable member. The catheter can define a plurality of openings along its length through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member. The device can also include a flow control sheath disposed around the catheter member such that axial movement of the flow control sheath relative to the catheter selectively occludes or uncovers one or more of the openings located proximal to the expandable member.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: June 25, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Kenneth Eliasen, Adam J. Yestrepsky
  • Patent number: 10328245
    Abstract: A method is disclosed for forming a coating layer on an outer surface of a balloon of a balloon catheter. The method includes supplying a coating solution containing a drug and a solvent through an end portion of a flexible dispensing tube with an opening portion for discharging the coating solution through the end portion of the flexible dispensing tube; keeping in contact an opening portion-formed end portion side of the dispensing tube with the outer surface of the balloon in such a manner as to be oriented in a direction opposite to a rotating direction of the balloon; rotating the balloon about an axis of the balloon; and discharging the coating solution through the opening portion and applying the coating solution to the outer surface of the balloon while the dispensing tube is moved relative to the balloon in an axial direction of the balloon.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: June 25, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Yasuo Kurosaki, Ryosuke Suzuki, Eisuke Furuichi
  • Patent number: 10328246
    Abstract: A medical device for anchoring itself and other medical devices while channeling blood flow through the center of a vessel proximal to the device's target area to minimize debris and the pressure necessary to move blood proximal to the device. The medical device also provides superior recoil reduction capabilities. A doughnut-shaped balloon that may be inflated and deflated by increasing and decreasing pressure within the balloon, having two passages therethrough, dimensioned for blood flow and a delivery device. A method for using the device.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: June 25, 2019
    Inventor: Daniel Ezra Walzman
  • Patent number: 10328247
    Abstract: A method of forming a coated medical device is described in which a coating including a therapeutic agent dispersed in a polymer or oligomer matrix is applied to an outer surface of the medical device. The coating is then post-processed to selectively remove a substantial portion of the polymer or oligomer matrix from the coating. The post-processed coating is then sterilized.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: June 25, 2019
    Assignee: The Spectranetics Corporation
    Inventor: Patrick H. Ruane
  • Patent number: 10328248
    Abstract: A controller, which may be used in a transdermal drug delivery apparatus, includes a housing, a pushing mechanism mounted for moving relative to the housing, a force provider positioned between the housing and the pushing mechanism for moving the pushing mechanism relative to the housing, and a latching mechanism for selectively restricting and allowing relative movement between the housing and the pushing mechanism. The pushing mechanism may be configured for pushing against a reservoir of the transdermal drug delivery apparatus. The latching mechanism may include flexible arms extending between the opposite ends of the latching mechanism, and the latching mechanism may be configured so that the arms release the pushing mechanism in response to the opposite ends being forced toward one another.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: June 25, 2019
    Assignee: SORRENTO THERAPEUTICS, INC.
    Inventors: Andrew T. Baker, Elizabeth Deibler Gadsby, Russell F. Ross, Luke Hagan
  • Patent number: 10328249
    Abstract: A system and method comprise positioning a medical device within a subject. The medical device includes a plurality of compartments and each of the plurality of compartments includes a ferrous material. Further, each of the plurality of compartments is configured to hold a substance. The system and method further include delivering electromagnetic radiation, by an electromagnetic radiation source, to the medical device and varying, by a controller, an amount of the electromagnetic radiation delivered by the electromagnetic radiation source for selectively heating the ferrous material of at least one of the plurality of compartments and selectively releasing the substance held in the at least one of the plurality of compartments for managing a condition.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: June 25, 2019
    Inventor: Bernard Fryshman
  • Patent number: 10328250
    Abstract: An adapter constructed to have a proximal portion that interfaces with the internal lumen of a medical device and a distal portion that modifies, augments or extends the configuration or intended use of the medical device. The proximal portion of the adapter interfaces with the internal lumen of the medical device in a manner to secure the adapter to the medical device during use. The distal portion of the adapter is generally outside the lumen of the catheter or device.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 25, 2019
    Assignee: COVELLUS LLC
    Inventor: Bradley Beach
  • Patent number: 10328251
    Abstract: A system to detect occlusion of an intravenous catheter may include a housing, which may include a distal end configured to couple to a proximal end of a catheter adapter and an inner lumen forming a fluid pathway. The system may also include one or more transmitters, which may be disposed within the housing. The transmitters may be configured to transmit first energy waves along a length of an intravenous catheter at a first frequency, and a portion of the first energy waves that are reflected back from the catheter may be detected by the system. Based on the portion of the first energy waves that are reflected back from the catheter, the transmitters may transmit second energy waves along the length of the catheter at a second frequency, which may be greater than the first frequency and configured to reduce formation of blood clots within the catheter.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: June 25, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: S Ray Isaacson, Erik K Witt
  • Patent number: 10328252
    Abstract: An antimicrobial IV access cap having an inner surface for retaining an antimicrobial agent, and further configured to receive a portion of an access port of an intravascular device.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: June 25, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Minh Quang Hoang, Jonathan Karl Burkholz, Kelly David Christensen
  • Patent number: 10328253
    Abstract: A medical lead includes a coiled conductor portion that defines at least part of an outer surface of the lead and an expandable coiled fixation element that defines at least a part of the outer surface of the lead. The expandable coiled fixation element is configured to expand from a first dimension in a first state to a second dimension in a second state in a direction away from the coiled conductor portion. In some examples, the expandable coiled fixation element comprises a shape memory material.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: June 25, 2019
    Assignee: Medtronic, Inc.
    Inventor: Patrick D. Wells
  • Patent number: 10328254
    Abstract: Systems and methods for applying stimulating current to a patient for treating insufficient uterine contractions are provided. The system includes stimulation electrodes of a balloon electrode array device, a ring electrode array device, an electrode probe device, or a mesh electrode array device. Some aspects of the invention also provide a connector and cable device for coupling the stimulation electrodes to electronics for generating and providing the stimulating current to the stimulation electrodes.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: June 25, 2019
    Assignee: Dignity Health
    Inventors: Robert E. Garfield, Harvey Carp, William L. Maner
  • Patent number: 10328255
    Abstract: The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: June 25, 2019
    Assignee: Precision NeuroTechnologies LLC
    Inventors: Benjamin I. Rapoport, Demetrios Papageorgiou, Jason Chen
  • Patent number: 10328256
    Abstract: Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods. A method for treating a patient in accordance with a particular embodiment includes selecting a neural modulation site to include a neural population of the patient's spinal cord, and selecting parameters of a neural modulation signal to at least reduce an autonomic system deficit in the patient.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: June 25, 2019
    Assignee: Nevro Corp.
    Inventor: Bradford Evan Gliner
  • Patent number: 10328257
    Abstract: An implantable medical device assembly includes a mounting structure, an electrode, and fixation tines. The electrode protrudes from a surface of the structure, offset proximally from a distal end of the structure, and approximately centered between first and second sides of the structure. Each tine extends away from the surface—a first adjacent the first side, and a second adjacent the second side. Each tine is elastically deformable from a relaxed condition, in which the tine extends toward a proximal end of the structure, to an extended condition, in which the tine extends away from the distal end of the structure. A delivery tool has first and second longitudinally extending sidewalls to receive passage of the structure therebetween. When the structure distal end is located between proximal ends of the sidewalls, a rail-like edge of each sidewall receives, and elastically deforms to the extended condition, a corresponding tine.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: June 25, 2019
    Assignee: Medtronic, Inc.
    Inventors: Teresa A Whitman, Matthew D Bonner, Jean M Carver, Raymond W Usher
  • Patent number: 10328258
    Abstract: Electrotherapeutic systems, devices, and methods are described. In one embodiment, a portion of a hepatic branch of a vagus nerve in a liver is stimulated with a lead implanted in the liver. In another embodiment, a stimulation member is delivered to a location in the gastrointestinal tract and implanted in a target area endoscopically and under ultrasound visualization. In another embodiment, a stimulation device is magnetically coupled to a stimulation member in order to electrically couple stimulation generation circuitry with a lead implanted in a target area.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: June 25, 2019
    Assignee: Cook Medical Technologies LLC
    Inventors: Shaun Davis Gittard, John Crowder Sigmon, Jr.
  • Patent number: 10328259
    Abstract: A system for treatment of biological tissues is provided. The system can deliver electric pulses to a targeted region within a biological tissue. The system includes an antenna assembly and a lens. The antenna assembly is configured to generate and direct electromagnetic radiation. The lens is configured to be positioned between a surface of the biological tissue and the antenna assembly. The lens can have a plurality of lossy portions. The lens can be configured to be adjustable to create a patient-specific desired electric field distribution by selective positioning of the plurality of lossy portions within the lens.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: June 25, 2019
    Assignee: Old Dominion University Research Foundation
    Inventors: Shu Xiao, Andrei Pakhomov, Karl H. Schoenbach
  • Patent number: 10328260
    Abstract: A disposable electrical stimulation device and method for providing therapeutic treatment and pain management in a convenient, compact configuration. Electrode size and shape and relative configuration can be varied according to an intended application and use, or a universal configuration can be provided for use on almost any area of the body. The common structure of communicatively coupled dual electrodes including control circuitry and a power source accommodates a range of different sizes, configurations, stimulation treatment intensities, and other physical and electrical characteristics that can be pre-customized and packaged for specific, limited time use. The device can therefore be used in methods of providing therapy, managing pain, and achieving other treatment goals by electrical stimulation.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: June 25, 2019
    Assignee: DJO, LLC
    Inventors: Pierre-Yves Mueller, Marshall Masko, Pierre-Yves Lampo, Klaus Schonenberger, Felix Buhlmann, Steve Guex, Gary L. Moore, Patrick Lavalley
  • Patent number: 10328261
    Abstract: Embodiments described herein generally relate to devices and methods for stimulation or recording of accommodation of an eye. Accommodation of an eye naturally occurs through contraction of the ciliary muscle. Embodiments described herein can deliver electrostimulation to the ciliary muscle through a pair of electrodes which deliver power over an area of the sclera which is both positioned above and over an area which is substantially equivalent to the surface area of the ciliary muscle. In further embodiments, electrical impulses produced by the ciliary muscle can be received by one or more electrodes positioned proximate the ciliary muscle. Thus, by embodiments described herein, accommodation of the eye can be reproducibly achieved by external stimulation of the ciliary muscle or measured based on electrical impulses generated by or in conjunction with the ciliary muscle.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: June 25, 2019
    Assignee: UNIVERSITY OF HOUSTON SYSTEM
    Inventor: Adrian Glasser
  • Patent number: 10328262
    Abstract: Described here are stimulation systems and methods for stimulating one or more anatomical targets in a patient for treatment conditions such as dry eye. The stimulation system may include a controller and a microstimulator. The components of the controller and microstimulator may be implemented in a single unit or in separate devices. When implemented separately, the controller and microstimulator may communicate wirelessly or via a wired connection. The microstimulator may generate pulses from a signal received from the controller and apply the signal via one or more electrodes to an anatomical target. In some variations, the microstimulator may include a passive generation circuit configured to generate a pulse based on a signal received from the controller.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: June 25, 2019
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Oculeve, Inc.
    Inventors: Douglas Michael Ackermann, James Donald Loudin, Janusz Kuzma, Daniel Palanker, Scott Franklin Wetenkamp
  • Patent number: 10328263
    Abstract: In a patient suffering from neural impairment, stimulation is provided to sensory surfaces of the face and/or neck, or more generally to areas of the body that stimulate the trigeminal nerve, while performing an activity intended to stimulate a brain function to be rehabilitated. The simulation may then be continued after the performance of the activity has ceased. It has been found that the patient's performance of the activity is then improved after stimulation has ceased. Moreover, it tends to improve to a greater extent, and/or for a longer time, when the post-activity stimulation is applied, as compared to when post activity stimulation is not applied.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: June 25, 2019
    Inventors: Yuri P. Danilov, Mitchell E. Tyler, Kurt A. Kaczmarek
  • Patent number: 10328264
    Abstract: A neurostimulation system delivers neurostimulation to a patient using one or more primary parameters and one or more secondary parameters. The one or more primary parameters are controlled for maintaining efficacy of the neurostimulation. The one or more secondary parameters are adjusted for preventing the patient from developing neural accommodation. In various embodiments, values for the one or more secondary parameters are varied during the delivery of the neurostimulation for prevention of neural accommodation that may result from a constant or periodic pattern of stimulation pulses.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: June 25, 2019
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jason J. Hamann, David J. Ternes, Stephen B. Ruble, Juan Gabriel Hincapie Ordonez
  • Patent number: 10328265
    Abstract: An example of a system may include an arrangement of electrodes configured to be operationally positioned for use in modulating targeted neural tissue, a neural modulator, a communication module, and a controller. The neural modulator may be configured to use at least some electrodes within the arrangement of electrodes to generate a modulation field. The communication module may be configured to receive user-provided selections. The controller may be configured to use the communication module to receive a user-provided selection of a desired electrode list where the electrode list identifies electrodes within the arrangement of electrodes that are available for use in modulating the targeted neural tissue, control the neural stimulation modulator to generate the modulation field, and use the electrodes identified in the electrode list to modulate the targeted neural tissue.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: June 25, 2019
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Michael A. Moffitt, Bradley Lawrence Hershey, Changfang Zhu, Jordi Parramon, Sridhar Kothandaraman
  • Patent number: 10328266
    Abstract: An external medical device includes at least one therapy electrode configured to be disposed on a patient; and a treatment manager configured to execute a baseline process to determine at least one of a range of values for a discomfort parameter and a patient discomfort threshold value corresponding to the at least one pacing routine, detect a cardiac condition of the patient, execute the at least one pacing routine, the at least one pacing routine being associated with the cardiac condition, monitor the discomfort parameter during execution of the at least one pacing routine, determine whether the discomfort parameter transgresses the at least one of the range of values and the patient discomfort threshold value, and adjust at least one characteristic of the at least one pacing routine upon the discomfort parameter transgressing the at least one of the range of values and the patient discomfort threshold value.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 25, 2019
    Assignee: ZOLL MEDICAL CORPORATION
    Inventors: Jason T. Whiting, Thomas E. Kaib, Rachel H. Carlson, Gregory R. Frank, Gary A. Freeman
  • Patent number: 10328267
    Abstract: A device can include a multi-dimensional posture sensor that provides an electrical sensor output representative of alignment of first, second, and third non-parallel axes of the device with the gravitational field of the earth, and a processor that includes a calibration circuit and a posture circuit. The calibration circuit measures a first sensor output for the first device axis and a second sensor output for one of a second device axis while the subject is in a first specified posture, measures sensor outputs for the first, second, and third device axes while the subject is in a second specified posture, calculates one or more coordinate transformations, generates transformed sensor outputs using the coordinate transformations, and calibrates the posture sensor by calculating a calibration transformation using the first and second sensor outputs and the transformed sensor outputs. The posture circuit determines a subsequent posture of the subject using the posture sensor.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: June 25, 2019
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: John D. Hatlestad, Tsz Ping Chang
  • Patent number: 10328268
    Abstract: A cardiac pacing system that includes a pulse generator to generate therapeutic electrical pulses and at least one lead inserted through an intercostal space in the region of a cardiac notch of the left lung of a patient, the lead having a distal end configured to transmit the therapeutic electrical pulses generated by the pulse generator to pace the heart of the patient.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: June 25, 2019
    Assignee: ATACOR MEDICAL, INC.
    Inventors: Rick Sanghera, Alan Marcovecchio, Sean P. McGeehan
  • Patent number: 10328269
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: June 25, 2019
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied