Abstract: An apparatus for assessing user frailty is disclosed. In embodiments, the apparatus includes a housing that defines (or is defined by) a body and a handle coupled to the body. The apparatus includes a force sensor at least partially disposed within the handle. The apparatus further includes an inertial sensor at least partially disposed within the housing. The apparatus may further include a user interface device disposed within a cavity of the body. The user interface device may be coupled to the force sensor and the inertial sensor via one or more signal paths. In embodiments, the user interface device includes a controller with a touchscreen coupled to the controller.

Abstract: A biological information measurement device includes a housing, a measurement unit disposed in the housing and sending and receiving light to and from a subject, and an arithmetic unit disposed in the housing and estimating first information related to a biological body from a signal depending on the light received by the measurement unit, wherein the housing includes an attachment portion for attachment of a second information measurement device configured to obtain, from the subject, second information related to the biological body, the second information being different from the first information.

Abstract: An apparatus (1) comprising a cuff configured to be worn around an upper arm of a user (75), a first sensor (S1) comprised in the cuff and configured to receive sounds through a side of the chest of the user, and a second sensor (S2) configured to receive sounds and to be movable with regard to the cuff and configured to be placed at a front side of the user's chest and used in conjunction with the first sensor.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: Embodiments of fluid pumps configured for use in a magnetic resonance imaging environment are disclosed. The pumps may include piezoelectric driven pumping mechanisms or ultrasonic motor driven pumping mechanisms. The pumps may be configured to pump fluid such as air or liquid. The pumps may be incorporated in a multi-parameter patient monitoring system.

Abstract: A method for time domain signal reconstruction for representing heart activity of a subject from a photoplethysmogram (PPG) signal comprises: receiving a PPG signal carrying information of heart activity of the subject; decomposing frequency information of the PPG signal into a plurality of components, each component having a frequency spectrum and a weight; for each component of the plurality of components: comparing the frequency spectrum of the component to a spectrum mask based on an estimate of heart rate of the subject; and adjusting the weight of the component based on the comparing; and reconstructing a time domain signal based on recombination of the plurality of components with adjusted weights.

Abstract: A biosensor including: a first electrode; a second electrode spaced from the first electrode; a channel unit electrically connected at a portion with the first electrode and electrically connected at another portion with the second electrode; a stimuli source electrically connected with the channel unit and applying an electric stimulus; and probes connected to the channel unit and complementarily bound with target materials to sense.

Abstract: A method and medical device for determining a cardiac episode that includes sensing a cardiac signal, identifying the signal sensed during a predetermined time interval as one of a cardiac event, a non-cardiac event, and an unclassified event, determining a number of identified cardiac events, determining a number of identified unclassified events, and determining whether the cardiac episode is occurring in response to the number of identified cardiac events being greater than a cardiac event count threshold and the number of identified unclassified events being less than an unclassified event count threshold.

Abstract: A biomagnetic field measuring apparatus enabling reliable biomagnetic field measurements in clinical practice, having a plurality of magnetic field sensors being arranged in an array in a sensor plane, including a plurality of first magnetic field sensors being designed and configured to measure a first component of the magnetic field, a plurality of second magnetic field sensors being designed and configured to measure a second component of the magnetic field, and a plurality of third magnetic field sensors being designed and configured to measure a third component of the magnetic field, the first, second and third components of the magnetic field being orthogonal to each other. Viewed perpendicular to the sensor plane, the first magnetic field sensors and the second magnetic field sensors are arranged essentially centrally and the third magnetic field sensors are arranged essentially around the first and second magnetic field sensors.

Abstract: In some embodiments, the PC-HEMT based microelectronic sensors are used in cardiovascular and pulmonary monitoring, detection and measurements of electrocardiography signals, detection of the primary heart activity signals and measurements of the central venous pressure and heart rate variability, measurements of the right and left atrium pressures, recording a phonocardiogram, detection of the S2-split phenomena, measurements of breath dynamics and lung activity diagnostics, monitoring the brain activity and measuring and monitoring electrical signals associated with an electroencephalogram, and eye pressure diagnostics.

Abstract: The exemplary systems and methods may be configured for use in the determination of ectopic beat-compensated electrical heterogeneity information. Electrical activity can be monitored by a plurality of external electrodes. Ectopic beat information can be detected. Ectopic beat-compensated electrical heterogeneity information can be generated based on the monitored electrical activity and the detected ectopic beat information.

Abstract: A method for generating an EEG signal is disclosed. Multiple signals from multiple electrodes applied to a user's scalp are measured. The signals correspond to electrical activity generated by the user's brain. Each of the signals is evaluated using a machine learning algorithm in real-time to determine a quality of each of the signals. One or more switches is activated between the electrodes to electrically-connect a plurality of the electrodes. An EEG signal is measured using the parallel-connected electrodes.

Abstract: A biological information measurement device includes a photoplethysmographic sensor that detects a photoplethysmographic signal, an envelope detection processor that generates an envelope of the photoplethysmographic signal, and an amplitude normalization processor that normalizes amplitude of the photoplethysmographic signal to a desired amplitude value based on amplitude of the envelope. The device further includes an adaptive line spectrum enhancer that is capable of varying a filter coefficient, suppressing an aperiodic component contained in the normalized photoplethysmographic signal, and outputting a periodic component. A biological information obtainment unit is provided to obtain biological information such as a pulse rate based on an output signal from the adaptive line spectrum enhancer.

Abstract: A method for characterizing an electrocardiogram, including receiving a first unipolar signal from a first location of a heart and a second unipolar signal from a second location of the heart. The method further includes generating a bipolar signal from the first and second unipolar signals, and analyzing the bipolar signal to delineate a time period during which the first and second locations generate a bipolar complex. The method also includes analyzing the first unipolar signal within the time period to determine an activation time of the first location.

Abstract: The present disclosure relates to a maternal monitoring transducer (20), comprising a housing (60), a substrate board (72), particularly a PCB (70), disposed in the housing (60) and comprising control components (74), and a displacement measurement arrangement (76) comprising a displacement-sensitive structure (78) that is arranged to detect deformations of a deflectable measurement section (80) of the substrate board (72), wherein the maternal monitoring transducer (20) supplies a signal that is representative of maternal motion. The disclosure further relates to a method of operating a maternal monitoring transducer (20).

Abstract: Methods and devices are provided comprising an implantable lead having electrodes configured to be located proximate to a heart, the electrodes defining a sensing vector through a region of interest in the heart. The method and system collect an intra-cardiac electrogram (EGM) signal associated with an event of interest and determining an global amplitude characteristic (GAC) and a global slope characteristic (GSC) from the EGM signal under control of one or more processors within an implantable medical device (IMD). A QRS start. time is defined, within the EGM signal, based on the GSC and determining a local amplitude characteristic (LAC) for a segment of the EGM signal within a search window of the GAC under control of one or more processors within an implantable medical device (IMD) A QRS end time is defined, within the EGM signal, based on the LAC; and calculating a QRS duration based on the QRS start time and QRS end time under control of one or more processors within an implantable medical device (IMD).

Abstract: The exemplary systems, methods, and interfaces may obtain and analyze electrode signals from a plurality of external electrodes. The electrode signals may include at least an anterior set of electrode signals and a posterior set of electrode signals. The anterior and posterior sets of electrode signals may be used to generate, or provide, various metrics of cardiac electrical heterogeneity and various graphical depictions that may be useful in assessing a patient's cardiac functionality.

Abstract: An electroencephalogram (EEG) system is disclosed. The EEG system includes an EEG controller and an EEG sensor that includes a contact surface, the contact surface including an electrically-conductive portion in communication with the EEG controller and a sensor release element in communication with the EEG controller, the sensor release element being configured to perform, in response to a signal from the EEG controller, a release action to reduce adhesion of an electrically-conductive gel between the contact of the sensor and the user's skin.

Abstract: A method for obtaining an electroencephalogram (EEG) of a user is disclosed. A reference sensor is attached to the user by connecting a first component of the reference sensor to a second component of the reference sensor, at least a portion of the first component being sub-dermally implanted on or adjacent to a mastoid process of the user. At least one active sensor is attached to the user. A first signal is detected from the reference sensor simultaneously as a second signal is detected from the at least one active sensor. The EEG is obtained based on the first signal and the second signal.

Abstract: The invention relates to a microelectrode array, comprising a plurality of electrodes for electrically measuring brain waves and an integrated optical stimulation unit for stimulating brain regions by means of optical signals, wherein the stimulation unit has one or more electrical light sources.

Abstract: There is provided a computer implemented method for adapting a neurofeedback treatment, comprising: receiving at least one patient brain state parameter indicative of a current brain state of a patient for application of a neurofeedback treatment; correlating the at least one patient brain state parameter with a set of neurofeedback treatments from a plurality of neurofeedback treatments stored in a dataset; iterating for members of the set of neurofeedback treatments: selecting one neurofeedback treatment from the set of neurofeedback treatments, wherein in each iteration another neurofeedback treatment is selected; administering the one neurofeedback treatment to the patient; calculate an effectiveness parameter associated with the one neurofeedback treatment administered to the patient based on measured outputs of at least one brain signal outputted by at least one sensor sensing the head of the patient; and designating an effective neurofeedback treatment according to the measured effectiveness parameter.

Abstract: The exemplary systems, methods, and interfaces may obtain and analyze electrode signals from a plurality of external electrodes. The electrode signals may include at least an anterior set of electrode signals and a posterior set of electrode signals. The anterior and posterior sets of electrode signals may be used to generate, or provide, various metrics of cardiac electrical heterogeneity and various graphical depictions that may be useful in assessing a patient's cardiac functionality.

Abstract: The exemplary systems, methods, and interfaces may obtain and analyze electrode signals from a plurality of external electrodes. The electrode signals may include at least an anterior set of electrode signals and a posterior set of electrode signals. The anterior and posterior sets of electrode signals may be used to generate, or provide, various metrics of cardiac electrical heterogeneity and various graphical depictions that may be useful in assessing a patient's cardiac functionality.

Abstract: An electronic device includes: a polymer film that is to melt at a predetermined temperature higher than a body temperature; at least one electronic component provided in the polymer film; and a first hydrophobic film provided on an opposite surface of the polymer film to a side of the polymer film to be attached to skin.

Abstract: Systems, articles, and methods for surface electromyography (“EMG”) sensors that combine elements from traditional capacitive and resistive EMG sensors are described. For example, capacitive EMG sensors that are adapted to resistively couple to a user's skin are described. Resistive coupling between a sensor electrode and the user's skin is galvanically isolated from the sensor circuitry by a discrete component capacitor included downstream from the sensor electrode. The combination of a resistively coupled electrode and a discrete component capacitor provides the respective benefits of traditional resistive and capacitive (respectively) EMG sensor designs while mitigating respective drawbacks of each approach. A wearable EMG device that provides a component of a human-electronics interface and incorporates such capacitive EMG sensors is also described.

Abstract: The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.

Abstract: Method and systems provide a tool to quantify sensory maps of the brain. Cortical surfaces are conformally mapped to a topological disk where local geometry structures are well preserved. Retinotopy data are smoothed on the disk domain to generate a curve that best fits the retinotopy data and eliminates noisy outliers. A Beltrami coefficient map is obtained, which provides an intrinsic conformality measure that is sensitive to local changes on the surface of interest. The Beltrami coefficient map represents a function where the input domain is locations in the visual field and the output is a complex distortion measure at these locations. This function is also invertible. Given the boundaries and the Beltrami map of a flattened cortical region, a corresponding visual field can be reconstructed. The Beltrami coefficient map allows visualization and comparison of retinotopic map properties across subjects in the common visual field space.

Abstract: The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.

Abstract: A device for measuring and diagnosing the galvanic skin response with a modified mouse equipped with a control processor, comprising four touch sensors made by contact electrodes located on the surface of the mouse at the hand grip, and interconnected with each other to form six measuring channels, wherein the mouse is equipped with a signal processor comprising a measuring unit which is divided into sections, the number of which corresponds to the number of measuring channels, where the measuring unit is connected in series with a microprocessor unit and a channel switch such that each section of the microprocessor unit is connected to one of the measuring channels and the channel switch is also connected back to the measuring unit so that each of its sections is connected by a separate input, while the microprocessor unit is further provided with an output for connection to the control computer.

Abstract: An apparatus includes an interface and a processor. The interface is configured to receive signals from a calibration probe inserted in an organ of a patient. The processor is configured to hold multiple electrode positions corresponding respectively to multiple electrodes attached externally to the patient, to evaluate, based on the received signals, multiple data points, each data point including (i) a respective measured coordinate of the calibration probe, and (ii) a respective set of electrical values indicative of respective impedances between the calibration probe and the multiple electrodes. The processor is further configured to evaluate, based on the multiple data points and on the electrode positions, an alternative position for a selected electrode to be repositioned, and to output an identification of the selected electrode and the evaluated alternative position.

Abstract: The invention relates to a method of providing an indication of a body composition parameter to a user. The method includes receiving a data value indicative of a body composition parameter, providing the data value to a first buffer, the first buffer storing data values received over a first given time period, comparing the data value with a first tolerance range determined from data values stored in the first buffer over the first given time period. If the data value falls within the first tolerance range, the data value is provided to a second buffer, the second buffer storing those data values provided from the first buffer over a second given time period longer than the first given time period. an indication of the body composition parameter is provided to the user based on an average of the data values stored in the second buffer.

Abstract: Systems and methods for marking the location and extent of an anatomical region-of-interest, such as a tumor, using magnetic seeds whose position and orientation are measured or otherwise detected using a detection device that includes two or more magnetic sensors are described. One or more magnetic seeds are implanted to mark and define the center and extent of an anatomical region-of-interest and a magnetic sensor-based detector system is used to accurately identify the location of the magnetic seeds.

Abstract: Physicians performing invasive procedures utilize instruments inserted into a human body to perform the procedures. Such procedures typically involve actions to be performed on specific targeted anatomical structures. During the procedure, nearby anatomical structures unrelated to the procedure should generally be avoided. A system and techniques are provided herein for monitoring the position of such unrelated nearby anatomical structures relative to one or more surgical instruments. The system emits a warning to a human operator such as a surgeon if one of the instruments is too close to a monitored anatomical structure.

Abstract: Disclosed is a method for selecting a suitable inhaler device to a user. The method comprises using a spirometer and a computer comprising a display. The method comprising the following steps: A) connecting the spirometer and the computer; B) the computer, or spirometer, indicating to the user to inhale through the spirometer; C) the spirometer sending flow over time data of the inhalation made to the computer; and D) the computer comparing the flow over time data with dose emission over time data for a range of inhalers and indicating the suitable inhaler from the range of inhalers as the inhaler with the largest dose emission within the flow over time data. Disclosed is also a system for establishing a suitable inhaler device. The system comprises a spirometer and a computer connectable to each other for data transfer. The spirometer or the computer is configured to indicate to the user to inhale through the spirometer.

Abstract: A method for analyzing an audio respiratory signal comprises capturing the audio respiratory signal from a subject using a microphone and partitioning the audio respiratory signal into a plurality of overlapping frames. The method further comprises calculating a fourier transform for each frame and determining a magnitude spectrum using the fourier transform of the plurality of overlapping frames. Additionally, the method comprises extracting a spectrogram using the magnitude spectrum and analyzing the spectrogram to determine characteristics pertaining to wheeze sounds in the audio respiratory signal.

Abstract: An electronic endoscope processor includes a converting means for converting each piece of pixel data that is made up of n (n?3) types of color components and constitutes a color image of a biological tissue in a body cavity into a piece of pixel data that is made up of m (m?2) types of color components, m being smaller than n; an evaluation value calculating means for calculating, for each pixel of the color image, an evaluation value related to a target illness based on the converted pieces of pixel data that are made up of m types of color components; and a lesion index calculating means for calculating a lesion index for each of a plurality of types of lesions related to the target illness based on the evaluation values calculated for the pixels of the color image.

Abstract: The present disclosure is directed towards an electronic device, method of using a device, and a method of making a device for estimating the nutritional status in an individual of any age or weight. The electronic device measures the circumference of a body part of an individual and determines a standard score value for the individual based upon a designated age and gender to estimate the nutritional status of the individual. The method includes measuring the circumference of a body part of an individual using the electronic device and determining a standard score value from the device to estimate the nutritional status of the individual.

Abstract: A method to identify feature points associated with the heart valve movement, heart contraction or cardiac hemodynamics is revealed. The mechanocardiography (MCG) is a technology that makes use of vibrational waveforms acquired using at least one gravity sensor attached on one of the four heart valve auscultation sites on the body surface. The data of the electrocardiography (ECG) is recorded simultaneously with the MCG The feature points are identified by comparing P, R and T points of synchronized ECG with the MCG spectrum. By the time sequences and amplitudes of the feature points, the method provides additional clinical information of cardiac cycle abnormalities for diagnosis.

Abstract: Sensors are provided for monitoring neuromuscular blockade in patients. In one embodiment, a sensor includes a first flexible substrate including a sensing element for measuring patient response to a stimulus, a second flexible substrate for providing the stimulus, the second flexible substrate including at least two electrodes, the first flexible substrate not connected to the second flexible substrate, and a common connector coupled to both the first flexible substrate and the second flexible substrate, the connector configured to couple to an NMT monitoring device.

Abstract: The present invention relates to a device (20) for detection of a vital signs related risk score (111) for a bed fall risk of an individual (2), the device (20) comprising a first port (3) for obtaining vital signs data (140) related to a vital sign of the individual (2) and a vital signs processing unit (9) for obtaining and processing the vital signs data (140) to generate a vital signs related risk score (111) indicating the bed fall risk of the individual (2) by detecting at least one risk factor from the vital signs data (140) and computing the vital signs risk score (111) from the at least one risk factor.

Abstract: A sports training and guidance platform network which intertwine various wearables is provided. The network includes at least one wearable containing one biosensor worn on a human body and one worn on a animal body, Timestamp biometric and other measurements and inputs from a data stream for both human and animals collected, analyzed, compared and accessed on one or more mobile device platforms. According, the wearable network will measure and compare various animal biosensor data, and motion i.e., accelerometers, gyroscopes with human biosensor data. A sports training toolkit which includes wearable biosensors, sensors, secure wearable communication network(s) and platform and system, applications and database information is also provided.

Abstract: A peg (3) is placed on a peg board (2) by a subject. A detection unit (32) detects a contact state between a peg body (31) and a body portion of the subject. A signal transmission unit (33) transmits a signal indicative of a detection result from the detection unit (32).

Abstract: A determination apparatus includes a first acquisition unit, a second acquisition unit, and a controller. The first acquisition unit acquires a facial photograph image, included in a medium holding the facial photograph image, as a first facial image. The second acquisition unit acquires a captured image obtained by capturing an image of an imaging area, in which the face of a driver is assumed to be located, at a start of driving and/or during driving. The controller extracts an image of the face of the driver as a second facial image from the captured image acquired from the second acquisition unit, compares the first facial image and the second facial image, and determines whether the driver is the person in the facial photograph image held by the medium.

Abstract: A device and method for measuring levels of individual lipids in a lipoprotein, the device being equipped with: an irradiation unit that can emit irradiation light having a first wavelength and irradiation light having a second wavelength at predetermined light intensities toward the inside of a living body from outside of the living body; a light intensity detection unit arranged at a predetermined distance apart from a position at which light is emitted from the irradiation unit or is arranged adjacent to the position, and can detect the intensities of first light and second light both emitted from the living body; a scattering coefficient calculation unit that can calculate a first scattering coefficient and a second scattering coefficient in the living body respectively on the basis of the intensities of a first light and a second light detected by the light intensity detection unit; and a lipid level calculation unit.

Abstract: An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.

Abstract: A method for sampling momentary blood glucose levels, especially in the context of self-performed measurements conducted by a diabetes patient or by a user who assists the patient. Also provided are methods for estimating long-term blood glucose levels and glycated hemoglobin (HbA1c) concentration and methods for estimating blood glucose variance from the data obtained with the sampling method. The sampling method is based on a measurement of momentary blood glucose level data at randomly distributed sampling moments. The advantage obtained with this method is that averages calculated from measurements conducted at randomly distributed sampling moments are independent of periodically recurring events in the user's daily or weekly routines. The systematic errors arising from such routines can therefore be avoided.

Abstract: A photoacoustic apparatus of the present invention obtains distribution information of concentration of a substance inside an object using electric signals originated from acoustic waves generated from the object irradiated with a plurality of lights having a plurality of wavelengths, and includes a signal processor for obtaining a plurality of sound pressure distribution information, obtains concentration information of the substance at a certain position based on an user input, and obtains distribution information of the concentration of the substance inside the object using the sound pressure distribution information, concentration information of the substance, and information on absorption of each of the lights having the plurality of wavelengths by the substance.

Abstract: Disclosed are a method, device and system for determining total circulating blood volume (BV) using a minimally invasive technique.

Abstract: A device and method yielding a blood analysis employable in combination with an introducer for a catheter for a concurrent testing of blood from the introducer flash chamber during placement of a venous catheter. The device employs a colorimetric blood analysis to provide the user a visually discernable alert to the results of tested blood concurrent with the placement of the catheter with the introducer.

Abstract: The invention provides systems and methods to determine cannabis impairment using gyroscopes to sense impaired movement of a suspect. The system includes a triaxial gyroscope assembly that transmits wireless signals indicative of the movement to a computing device configured to receive and store the signals and compute and display cannabis impairment of the suspect based on the signals. The method identifies cannabis impairment, including attaching a triaxial gyroscope assembly to a suspect, computing signals indicative of the movement, transmitting the signals to a computing device, and displaying an indicator of cannabis impairment on the computing device.