Abstract: A capacitive vapor sensor, sensor system, and method for determining a vapor concentration is provided. The capacitive sensor includes a first electrode and a second electrode. The first and second electrodes are configured to provide a bias voltage. The sensor further includes a cantilevered sensor electrode interdigitated between the first and second electrodes and having an adsorptive polymer attached to a surface of the cantilevered sensor electrode. The adsorptive polymer is configured to expand in response to adsorbing a vapor and cause a deflection of the cantilevered sensor electrode, the deflection causing a change in a differential capacitance of the first and second electrodes. A sensor indicates current at the cantilevered sensor electrode, and an electronic processor determines the change in the differential capacitance to determine a characteristic or concentration of the vapor.

Abstract: Provided is an electrostatic capacitance detection device including: an electrode pair including a pair of electrodes, the electrode pair being arranged inside a compressor configured to compress refrigerant; a capacitor being connected in series to the electrode pair; an inverter having one of power lines connected to one end of series-connected electrode pair and capacitor, and is configured to drive the compressor, the power lines being used for driving the compressor; and a voltage detecting unit configured to measure a voltage between the pair of electrodes of the electrode pair.

Abstract: The present invention relates to an apparatus and a method for separating single cells, and the apparatus includes: a fluid channel which has an upper panel and a lower panel and has a flow path which is formed between the upper panel and the lower panel and configured to convey a sample including a single cell; a single cell measuring unit which includes first and second electrodes which are provided on the fluid channel so as to be spaced apart from each other at a predetermined interval and apply electrical signals to the sample being conveyed through the flow path of the fluid channel, and a detection electrode which is provided between the first electrode and the second electrode and detects the single cell in the sample being conveyed through the flow path, such that the single cell measuring unit applies the electrical signals to the sample being conveyed through the flow path, detects the electrical signals of the sample to which the electrical signals are applied, and detects whether there is the sin

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

Abstract: The present invention provides a method of obtaining miRNA biomarkers by data-search of up-regulated microRNAs (miRNAs) in cancer and screening the miRNA biomarkers to identify cancer kind- and stage-specific miRNA biomarker(s) using cancer cells, tissues and biological fluids. This invention includes obtaining lung cancer-specific miRNA biomarkers including early (Stage I) lung cancer miRNA biomarkers and identification of anti-cancer miRNA (complementary miRNA, DNA and their derivatives) in order to ameliorate diseases. This invention relates to novel utility of nanowell electrodes to detect target molecules in biological samples. The invention teaches methods to increase sensitivity of nanowell electrodes to detect target molecules including miRNA, RNA and DNA in biological samples to diagnose cancer and other diseases and monitoring prognosis and response to therapy.

Abstract: An electrochemical sensor device that is efficiently and economically produced at the chip level for a variety of applications is disclosed. In some aspects, the device is made on or using a wafer technology whereby a sensor chamber is created by said wafer and a gas port allows for a working electrode of the sensor to detect certain gases. Large scale production is possible using wafer technology where individual sensors are produced from one or more common wafers. Integrated circuits are made in or on the wafers in an integrated way so that the wafers provide the substrate for the integrated circuitry and interconnects as well as providing the definition of the chambers in which the gas sensors are disposed.

Abstract: An electrochemical gas sensor for detecting a target gas includes a housing comprising at least one gas inlet, an electrolyte within the housing, at least one working electrode in ionic contact with the electrolyte, at least one counter electrode in ionic contact with the electrolyte and at least one secondary electrode in ionic contact with the electrolyte. The secondary electrode is configured so that reaction of the target gas entering the housing via the at least one gas inlet at the at least one secondary electrode is less than reaction of the target gas at the least one working electrode. The electrochemical gas sensor further includes electronic circuitry in operative connection with the at least one working electrode, the at least one counter electrode and the at least one secondary electrode. The electronic circuitry is configured to measure an output from the at least one working electrode, and to measure an output from the at least one secondary electrode.

Abstract: An electrochemical gas sensor device with small physical footprint is disclosed. The electrodes within the element are arranged about the electrolyte such that the electrical impedance of the sensor is minimized. This results in a fast stabilization after detecting gasses and enables rapid changes in bias voltage to target different gasses. Gasketing elements, or alternative designs, are included to eliminate the diffusion of gasses between the electrodes within the cell.

Abstract: The present invention provides a gas sensor capable of suppressing a variation of a sensor output by a sensor cell to be small. A sensor element of a gas sensor comprises a first solid electrolyte body and a second solid electrolyte body having oxygen ion conductivity, a measured gas chamber into which the measured gas is introduced, a first reference gas chamber and a second reference gas chamber into which reference gas is introduced, a first pump cell, a second pump cell, a sensor cell, and a heater. A value obtained by dividing a first average cross-sectional area of the first reference gas chamber by the first length is larger than the value obtained by dividing the second average cross-sectional area of the second reference gas chamber by the second length.

Abstract: A sensing system and a method utilizing same for determining and/or monitoring a presence and/or level of an analyte in a sample are provided. The sensing system is made of a nanostructure, or a plurality of nanostructures, having covalently attached thereto and a hydrogel having associated therewith a sensing moiety which selectively interacts with the analyte and being configured such that upon contacting the analyte, the nanostructure(s) exhibit a detectable change in an electrical property.

Abstract: Systems and methods for a treatment of chemical sensors placed in a wellbore. A method may comprise providing a chemical sensor disposed in a sensing chamber, wherein the chemical sensor is on an optical fiber installed in a wellbore; optically interrogating the chemical sensor with the optical fiber; and pumping a treatment fluid through a fluid supply line and into the sensing chamber.

Abstract: A sensor for detecting lead in an aqueous solution includes a copper working electrode, a counter electrode, a power supply for applying underpotential deposition of lead onto the copper electrode from the aqueous solution, a measuring device for providing measurement of a hydrogen evolution reaction (HER) current on the Pbupd-modified electrode, and a means for correlating the degree of suppression of the HER current to Pbupd coverage to determine the lead coverage and lead concentration of the solution.

Abstract: A method for glycan profiling by capillary electrophoresis (CE), and a CE system for glycan analysis (N-Glycan). The CE system uses integrated dual optical fibers for both radiation excitation and emission detection. The CE system is configured for performing a two-color detection for data analysis. A single radiation excitation source is used to excite two emission fluorophores or dyes in the sample solution to be analyzed. One emission dye is to tag the sample and the other dye is used to provide a reference marker (e.g., a Dextran Ladder) for the sample run. Two detectors (e.g., photomultipler tubes (PMTs)) are applied to simultaneously detect the fluorescent emissions from the dyes. The data collected by both detectors are correlated (e.g., synchronized, and/or super-positioned for analysis) for accurate data peak identification.

Abstract: An ionization method for use with mass spectrometry or ion mobility spectrometry is a small molecule compound(s) as a matrix into which is incorporated analyte. The matrix has attributes of sublimation or evaporation when placed in vacuum at or near room temperature and produces both positive and negative charges. Placing the sample into a region of sub-atmospheric pressure, the region being in fluid communication with the vacuum of the mass spectrometer or ion mobility spectrometer, produces gas-phase ions of the analyte for mass-to-charge or drift-time analysis without use of a laser, high voltage, particle bombardment, or a heated ion transfer region. This matrix and vacuum assisted ionization process can operate from atmosphere or vacuum and produces ions from large (e.g. proteins) and small molecules (e.g. drugs) with charge states similar to those observed in electrospray ionization.

Abstract: A sensor apparatus according to an embodiment of the present invention includes an element substrate, an element electrode located on an upper surface of the element substrate, an insulating member covering at least a part of the element electrode, and a detection part that includes an immobilizing film located on the upper surface of the element substrate or an upper surface of the insulating member, and performs a detection of a detection object contained in a specimen. A surface roughness of the immobilizing film is smaller than a surface roughness of the element electrode. In a sensor apparatus of other embodiment of the present invention, an amount of oxygen in a surface layer part of the immobilizing film is smaller than an amount of oxygen in a surface layer part of the element electrode.

Abstract: The present disclosure provides an aerosol sensing method. The aerosol sensing method includes steps of providing an entering process, providing a particle collecting process and providing a measuring process. The entering process is to allow an aerosol to enter a chamber of a thermal-piezoresistive oscillator-based aerosol sensor, and a thermal-piezoresistive resonator is disposed in the chamber. The particle collecting process is to allow particulate matters in the aerosol to land on at least one proof-mass of the thermal-piezoresistive resonator when the thermal-piezoresistive resonator is not driven. The measuring process is to use an electrical signal to drive the thermal-piezoresistive resonator and measure a resonant frequency of the thermal-piezoresistive resonator. The particle collecting process and the measuring process are operated in a repetitive cycle for measuring changes of the resonant frequency of the thermal-piezoresistive resonator to measure the particulate matters of the aerosol.

Abstract: Ultrasonic transmitting elements in an electroacoustical transceiver transmit acoustic energy to an electroacoustical transponder, which includes ultrasonic receiving elements to convert the acoustic energy into electrical power for the purposes of powering one or more sensors that are electrically coupled to the electroacoustical transponder. The electroacoustical transponder transmits data collected by the sensor(s) back to the electroacoustical transceiver wirelessly, such as through impedance modulation or electromagnetic waves. A feedback control loop can be used to adjust system parameters so that the electroacoustical transponder operates at an impedance minimum. An implementation of the system can be used to collect data in a vehicle, such as the tire air pressure. Another implementation of the system can be used to collect data in remote locations, such as in pipes, enclosures, in wells, or in bodies of water.

Abstract: A method for measuring mechanical parameters of a multilayer composite thin film structure and belongs to the technical field of online tests of micro-electro-mechanical system (MEMS for short) material parameters. Equivalent Young modulus and equivalent residual stress of each layer of the multilayer composite thin film structure can be obtained in one step by means of solving an equation set on the basis of a relationship between first-order resonance frequency of multilayer composite fixed-fixed beams and multilayer composite cantilever beams and parameters such as material characteristics and structure size, the online test of multilayer thin film materials can be realized, the test structure and calculating method are simple, and the accuracy is higher. The present invention further discloses a device for measuring mechanical parameters of the multilayer composite thin film structure.

Abstract: Embodiments include an electromagnetic acoustic transducer (EMAT) system. The EMAT system includes a plurality of magnets and a conductor set. The plurality of magnets has a like pole arrangement and wherein each magnet is in close proximity to one another. The conductor set includes electrically conductive elements. A portion of the conductor set is positioned proximate to the plurality of magnets. The plurality of magnets and the conductor set are positioned proximate to a test object. The EMAT system is configured to perform at least one of generating and receiving an elastic wave. Embodiments also include a method of elastic wave measurement for nondestructive testing and evaluation.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: Exemplary embodiments are directed to methods and systems for managing fluid decompression. A fluid connector is located downstream of a chromatography column and defines an interior bore through which a fluid can pass. The interior bore has a reduced internal diameter at a downstream end compared to an upstream portion of the fluid connector. A cooling system is configured to cool a portion of the fluid connector at or below a threshold temperature value associated with a phase separation of the fluid. A detector is located downstream of the fluid connector, and the detector is configured to receive the fluid exiting the cooled fluid connector.

Abstract: A nano-flow fractionator apparatus, comprises: one or more sources of mobile phase solvent; a source of auxiliary solvent; a sample injection valve; a chromatographic column having an inner diameter of less than or equal to 75 micro-meters, a column inlet end and a column outlet end; a solvent fraction delivery line comprising: an inlet end that is configured to receive eluate that is emitted from the column outlet end and an outlet end that is configured to dispense the eluate to each of a plurality of sample fraction containers; a fluid junction configured to receive the eluate that is emitted from the column outlet end and to receive a flow of the auxiliary solvent that is delivered from the source of auxiliary solvent and to deliver the eluate and the flow of auxiliary solvent to the solvent fraction delivery line.

Abstract: This disclosure provides quantitative, rapid, and reliable LC-MS/MS methods for analyzing panels of pesticides and mycotoxins in various samples, including very hydrophobic and chlorinated compounds normally analyzed on a GC-MS/MS system. The methods can be carried out using a single instrument and can detect and quantify levels of the pesticides and mycotoxins that are well below action limits specified by U.S. states (e.g., California) and other countries (e.g., Canada) for these compounds in cannabis products.

Abstract: An odor measurement apparatus includes an odor sensor detecting an odor and an imaging device having a lens portion, in which an imaging direction of the imaging device and an introduction direction of air when the air is guided to a sensor surface of the odor sensor through an introduction port are substantially the same direction. The odor measurement apparatus detects odor substances contained in air using a sensor when an odor is measured, and measures attribute information of a measurement target or the like of the odor. An odor data management apparatus stores and manages odor data measured by the odor measurement apparatus.

Abstract: A method, system, and apparatus are provided for improving accuracy of sensor readings reflecting measurements of at least one constituent in an engine exhaust. The sensor measurement is corrected or compensated for by applying to a gain correction factor to the reported sensor measurement. The gain correction factor is developed by determination of prior test sensor readings correlated with discrete sensor age levels, and with constituent concentrations to which those test sensors are exposed. By applying the determined gain correction factor to change the sensor's reported measurements, bias may be reduced and a more accurate measure of actual constituent levels is provided.

Abstract: An artificial olfactory sensing system includes a sensor unit. The sensor unit includes a semiconductor device equipped with a transistor and a sensor cell in which an olfactory receptor is manifested on a lipid film. A proton adsorption film is formed on a gate electrode of the transistor. A physiological aqueous solution is disposed on the proton adsorption film. Then, the sensor cell is disposed in the physiological aqueous solution. A proton is adsorbed onto the proton adsorption film. When the olfactory receptor recognizes an odor molecule, the positive ions in the physiological aqueous solution flow from an ion channel of the olfactory receptor into the sensor cell. As a result, the proton is dissociated from the proton adsorption film into the physiological aqueous solution, and the potential of the gate electrode is changed.

Abstract: A gas sensor includes an adjustment unit having a concentration adjuster which changes the concentration of a particular gas component contained in measured gas introduced into a first chamber, a sensor unit having a second chamber for receiving the measured gas which has passed through the adjustment unit and a detector whose electrical characteristic changes with the concentration of the particular gas component, a single heater for heating the concentration adjuster and the detector, and a gas flow tube having the form of a pipe, at least partially running externally of the adjustment unit and of the sensor unit, and adapted to establish communication between the first chamber and the second chamber. The adjustment unit, the sensor unit, and the heater are united together in such a manner as to establish thermal coupling between the adjustment unit and the heater and thermal coupling between the sensor unit and the heater.

Abstract: An analytics system uses soil health indicators to determine metrics for soil samples. In an embodiment, the analytics system receives metadata describing a soil sample, where the metadata indicates one or more types of crops grown in a geographical location having the soil sample. The analytics system determines nucleic acid sequence reads of the soil sample. The analytics system determines taxonomic information of the nucleic acid sequence reads. The analytics system determines microbial composition of the soil sample using the taxonomic information. The analytics system determines reference metrics of soil samples from geographical locations in which the one or more types of crop were grown. The analytics system determines a metric of the soil sample using the microbial composition and the reference metrics. The analytics system transmits the metric to a client device.

Abstract: A condition diagnosis and a life-extending treatment method for an electric apparatus comprising insulation oil and a system to perform the method and comprises addition of a specific group, phospines, of chemical substances to protect metals in transformers and other insulating oil filled apparatuses from sulphidation caused by elemental sulphur.

Abstract: Systems and methods are described herein. The method generally includes generating frequency responses of one or more sample fluids having known fluid properties, selecting an equivalent circuit model for modeling the frequency responses, the equivalent circuit model including one or more model elements, calculating an equivalent impedance of the equivalent circuit model, generating a correlation between the one or more model elements and the known fluid properties, measuring an impedance of a drilling fluid, and determining at least one property of the drilling fluid based on the correlation between the one or more model elements and the known fluid properties.

Abstract: A method of board lumber (Table 2) grading is performed in an industrial environment on a machine learning framework (12) configured as an interface to a machine learning-based deep convolutional network (20) that is trained end-to-end, pixels-to-pixels on semantic segmentation. The method uses deep learning techniques that are applied to semantic segmentation to delineate board lumber characteristics (Table 1), including their sizes and boundaries.

Abstract: Methods and apparatus for long read, label-free, optical nanopore long chain molecule sequencing. In general, the present disclosure describes a novel sequencing technology based on the integration of nanochannels to deliver single long-chain molecules with widely spaced (>wavelength), ˜1-nm aperture “tortuous” nanopores that slow translocation sufficiently to provide massively parallel, single base resolution using optical techniques. A novel, directed self-assembly nanofabrication scheme using simple colloidal nanoparticles is used to form the nanopore arrays atop nanochannels that unfold the long chain molecules. At the surface of the nanoparticle array, strongly localized electromagnetic fields in engineered plasmonic/polaritonic structures allow for single base resolution using optical techniques.

Abstract: A method of forming a plurality of lipid bilayers over an array of cells in a nanopore based sequencing chip is disclosed. Each of the cells comprises a well. A first salt buffer solution with a first osmolarity is flowed over a cell in the nanopore based sequencing chip to substantially fill a well in the cell with the first salt buffer solution. A lipid and solvent mixture is flowed over the cell to deposit a lipid membrane over the well that encloses the first salt buffer solution in the well. A second salt buffer solution with a second osmolarity is flowed above the well to reduce the thickness of the lipid membrane, wherein the second osmolarity is a lower osmolarity than the first osmolarity such that an osmotic imbalance is created between a first volume inside the well and a second volume outside the well.

Abstract: The present disclosure relates to a method of screening an antibody or an antigen-binding fragment thereof by use of patient-derived tumor spheroids, and more particularly to a method of screening an antibody or an antigen-binding fragment thereof, which binds specifically to an antigen, by use of patient-derived tumor spheroids containing the antigen.

Abstract: An animal-based chemical detectors that can be customized to detect a wide variety of chemicals under real-world conditions. Methods and systems for brain/machine interface devices using electrodes to read odor-signatures from the patterns of activated glomeruli, for example in the rodent olfactory bulb.

Abstract: Illustrative systems, methods and non-transitory computer-accessible mediums are provided for aligning a focal plane and a sample plane to be imaged.

Abstract: The invention relates to compositions and methods for the concentration and/or purification of analytes, such as biomarkers, typically from complex biological samples such as whole blood, serum or plasma. This invention also relates to the use of binding agents, such as antibodies, aptamers, antigens and engineered protein scaffold based binding agents (e.g. commercially available Affibodies®), to facilitate the concentration and/or purification of said analytes. This invention further relates to assays used to detect, measure and/or quantify the analyte after its concentration and/or purification, preferably solid-phase immunoassays and more preferably multiplex solid-phase immunoassays.

Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of hyaluronic acid (HA) as diagnostic and prognostic biomarker assays in renal injuries.

Abstract: The invention relates to a sensor molecule for detecting a target molecule comprising: (a) a rod-like molecule L and a rod-like molecule R connected to each other by a joint molecule C to form a hinge; (b) a target binding molecule A bonded to the end of rod-like molecule L opposite to the joint molecule C; (c) a binding molecule A? bonded to the end of rod-like molecule R opposite the joint molecule C; wherein the target binding molecule A is arranged to bind to an epitope or nucleic acid sequence of the target molecule to be detected, and binding molecule A? is arranged to bind to the same epitope or same nucleic acid sequence, or portion thereof of the target molecule as target binding molecule A; and wherein the hinge is biased into an open position, such that target binding molecule A and binding molecule A? are biased apart by the hinge. The invention also relates to analyte dependent activation of pharmaceuticals and chemo-toxins.

Abstract: The process of aging and the development of age-related diseases are related to the emerging phenotypes of increasingly damaged and progressively malfunctioning proteomes. The present invention provides methods of preventing aging and age-related diseases in mammals by assessment of protein-specific oxidative damage. Methods of providing treatments that reduce intracellular reactive oxygen and/or nitrogen species, or protein-specific damage caused by reactive oxygen and/or nitrogen species, are disclosed. Furthermore, methods of screening for compounds that reduce intracellular reactive oxidative species, and/or molecules that prevent protein-specific damage by protecting the susceptible protein from such damage and therefore prevent or treat degenerative or age-related diseases, are also disclosed.

Abstract: A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

Abstract: There is disclosed a microarray having base cleavable linkers and a process of making the microarray. The microarray has a solid surface with known locations, each having reactive hydroxyl groups. The density of the known locations is greater than approximately 100 locations per square centimeter. Optionally, oligomers are synthesized in situ onto the cleavable linkers and subsequently cleaved using a cleaving base. Optionally, the oligomers are cleaved and recovered as a pool of oligomers.

Abstract: The invention relates to a method of determining the dissociation rate constant (koff) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein the cell has bound to it such a combination of cell labeling. The invention further relates to a kit and an apparatus useful in performing the methods of the invention. The invention further relates to a method of isolation a high-avidity T cell.

Abstract: Provided herein are methods of identifying a protein capable of binding a ligand, the method comprising: (a) contacting the ligand with two or more samples comprising a plurality of proteins in a solution; (b) separating the proteins bound to the ligand (“bound proteins”) from the proteins that are not bound to the ligand (“unbound proteins”) in each sample; (c) denaturing and digesting the bound proteins to form a plurality of peptides in each sample; (d) quantifying a plurality of molecular features contained in the plurality of peptides in each sample, wherein the molecular features are defined as having a mass to charge ratio, retention time, and peak intensity as measured by mass spectrometry; and (e) ranking the molecular features that exhibit a statistically significant difference in quantity between the samples contacted with the ligand and a sample that is not contacted with the ligand (“statistically significant molecular feature”).

Abstract: The present invention provides new and improved methods for screening for and/or identifying T cell epitopes, as well as various assays and compositions (such as nucleic acid molecules, vectors, viruses, peptides, libraries, and cells), that are useful in carrying out such methods. Such methods and compositions can be used to predict and/or study the toxicity and off-target effects of T-cells, TCRs, or TCR-like molecules.

Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).

Abstract: The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens that, separated from each other, are applied to a solid phase, wherein at least the following antigens are used: aa) the “non-structural protein 1” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, bb) an “envelope protein” of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, cc) an “envelope protein” of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, dd) the “non-structural protein 1” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and ee) an “envelope protein” of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids, b) the solid phase is washed to separate non-specific

Abstract: This invention is directed to methods for the facile and accurate identification of cancer cells in a tissue sample, such as a surgical field. In particular, the compositions and methods employ conjugates comprising pro-fluorescent fluorescein based moieties bound to folic or pteroic acid targeting moiety optionally through a linker. The pro-fluorescent fluorescein based moieties are non-fluorescent but capable of being rendered fluorescent by intracellular processes. The conjugates are employed to detect cancer cells that overexpress folic acid receptors thereby providing for differential accumulation of these conjugates in these cells.

Abstract: [Problem] The present invention addresses the problem of providing a novel biomarker which makes it possible to find the prognosis of glioma, the risk of distant recurrence of glioma, the invasion ability of glioma cells and the like and also makes it possible to detect the prognosis, the risk, the invasion ability or the like in an earlier stage of a therapy of glioma. [Solution] The present invention relates to a method for evaluating the prognosis of glioma, said method comprising the steps of: detecting ACTC1 protein and/or mRNA encoding the protein in a glioma-containing sample collected from a patient; and determining that the prognosis of the glioma is poor when the ACTC1 protein and/or the mRNA encoding the protein is detected in the aforementioned step. According to the present invention, the prognosis of glioma, the risk of distant recurrence of glioma, the invasion ability and the like can be evaluated using a novel biomarker, i.e., ACTC1 protein and/or mRNA encoding the protein.

Abstract: Provided herein are methods for determining a diagnosis and/or prognosis for prostate cancer using the ratio of FOXC1:FOXA1 in a sample obtained from a subject.