Abstract: A surgical illumination apparatus comprises a fiber optic input, and illuminated surgical instrument, and an optical coupling bracket for coupling the fiber optic input to the illuminated surgical instrument. The coupling bracket comprises an elongate frame having a proximal end, a distal end, and a central channel extending therebetween, wherein the central channel is sized to receive and support optical fibers of the fiber optic input. The proximal end of the bracket is coupled to the fiber optic input, and the distal end of the bracket is coupled to an illumination element of the illuminated surgical instrument. The apparatus may further comprise a shroud disposed around the illumination element that is coupled to the bracket.

Abstract: An ultrasonic communication system and method provide a networking framework for wearable devices based on ultrasonic communications. The ultrasonic communication system and method incorporate a set of physical, data link, network and application layer functionalities that can flexibly adapt to application and system requirements to efficiently distribute information between ultrasonic wearable devices.

Abstract: A control method of an information terminal causes a display to display a display screen which includes a first display region and a second display region. The first display region displays an object medical image. The second display region displays M number of similar medical images and includes ND number of individual regions for displaying the M number of the similar medical images. When an instruction from one or more instruction buttons is detected, a display size of each corresponding region of interest that is included in the second number of the similar medical images is changed while maintaining a size of each of the individual regions in the second display region, and each of the similar medical images is magnified at a magnification ratio of a reference thumbnail.

Abstract: A method is for providing a medical image of a patient. The method includes acquiring medical measurement data of the patient, including a set of multiple sampled state combinations; a first state space, including first physiological states, and a second state space, including second physiological states, together spanning a third state space. Each of the combinations includes a state from the first and second state spaces, and the third state space includes the set of combinations. The method further includes generating a medical image of the patient using the medical measurement data acquired, including a further state combination; the further state combination including a state from the first and second state space, the third state space including the further state combination, and the further state combination lying within the third state space outside the set of combinations. Finally, the method includes providing the medical image of the patient generated.

Abstract: An optical measuring device including a light source, a light beam path adjuster, a light detector and a controller is provided. The light source may emit light toward an object in a predetermined progress direction. The light beam path adjuster may be disposed between the light source and the object and may change a progress path of the light emitted from the light source. The light detector may receive the light that is reflected from the object after passing through the light beam path adjuster. The controller may compare a first effective beam path length of the reflected light that the light detector receives with a predetermined target beam path length and control a refractive angle of the light beam path adjuster based on a beam path length difference between the first effective beam path length and the predetermined target beam path length.

Abstract: An exemplary system, method and computer-accessible medium for determining a characteristic(s) of a tissue(s), can be provided which can include, for example, ablating the tissue(s), illuminating the tissue(s) during the ablation procedure; and continuously determining the characteristic(s) based on the ablation and illumination procedures. The tissue(s) can be ablated using radiofrequency ablation. The illumination procedure can be performed with a radiation in a visible spectrum.

Abstract: A 3D scanner system for detecting and/or visualizing cariogenic regions in teeth based on fluorescence emitted from said teeth, the 3D scanner system including data processing means configured for mapping a representation of fluorescence emitted from the teeth onto the corresponding portion of a digital 3D representation of the teeth to provide a combined digital 3D representation.

Abstract: A system for determining a clinically relevant temperature differential between a predetermined area of interest, as defined herein, on the body surface of a mammal and a control area on the body surface of said mammal, said system comprising: a visual and thermal image capturing device, said image capturing device comprising: a housing, a means for capturing a digital visual image within said housing; and a means for capturing a digital thermal image within said housing; a display apparatus, said display apparatus comprising means for showing said captured visual image and said captured thermal image; and a computing apparatus, said computing apparatus operatively connected to said image capturing device and to said display apparatus, said computing apparatus comprising: a means for selecting a control area on the surface of the skin; a means for determining an temperature of said control area; a means for selecting an area of clinical interest within said visual image; a means for calculating plane geometri

Abstract: A method for detecting an artifact of a blood pressure signal includes measuring consecutive signals of blood pressure in real time, dividing the consecutive signals into a plurality of unit waveforms by searching systolic starting points and peak points from the measured signals, determining two outputs by applying N consecutive unit waveforms among the plurality of unit waveforms as an input to a deep belief network (DBN), and determining whether the signal is an artifact or a normal signal by using the two determined outputs. According to the present disclosure, it is possible to minimize various false alarms of bio-signal streams which are measured in real time by automatically eliminating ABP artifacts using a deep belief network (DBN) which is one of deep neural network (DNN) models capable of learning causes and shapes of various types of artifacts together.

Abstract: An earphone includes a loudspeaker, a microphone, a housing supporting the loudspeaker and microphone, and an ear tip surrounding the housing and configured to acoustically couple both the loudspeaker and the microphone to an ear canal of a user, and to acoustically close the entrance to the user's ear canal. A processor receives input audio signals from the microphone, detects peaks having a frequency of around 1 Hz in the input audio signals, based on the detected peaks, computes an instantaneous heart rate, measures a frequency of an oscillation within the instantaneous heart rate, and based on the frequency of the oscillation, computes a rate of respiration.

Abstract: A photoacoustic image evaluation apparatus includes a processor configured to acquire a first photoacoustic image generated at a first point in time and a second photoacoustic image generated at a second point in time before the first point in time, the first and second photoacoustic images being photoacoustic images generated by detecting photoacoustic waves generated inside a subject, who has been subjected to blood vessel regeneration treatment, by emission of light into the subject; acquire a blood vessel regeneration index, which indicates a state of a blood vessel by the regeneration treatment, based on a difference between a blood vessel included in the first photoacoustic image and a blood vessel included in the second photoacoustic image; and display the blood vessel regeneration index on a display.

Abstract: A wireless, patient-worn, physiological sensor configured to, among other things, help manage a patient that is at risk of forming one or more pressure ulcers is disclosed. According to an embodiment, the sensor includes a base having a top surface and a bottom surface. The sensor also includes a substrate layer including conductive tracks and connection pads, a top side, and a bottom side, where the bottom side of the substrate layer is disposed above the top side of the base. Mounted on the substrate layer are a processor, a data storage device, a wireless transceiver, an accelerometer, and a battery. In use, the sensor senses a patient's motion and wirelessly transmits information indicative of the sensed motion to, for example, a patient monitor. The patient monitor receives, stores, and processes the transmitted information.

Abstract: Disclosed methods and systems may be operable to obtain non-contact diagnostic information about movements of scattering objects such as fluids in subsurface vasculature in tissue. As an example, a method may include causing a light source to illuminate the tissue with at least a first portion of the emitted light and illuminate an optical modulator with at least a second portion of the emitted light. The second portion of the emitted light may be modulated by the optical modulator. An offset source is configured to provide an offset frequency signal. An image sensor may receive optical information from the sample. A heterodyne signal based on the reference frequency signal and the offset frequency signal may be used as a gain input of each detector element of the image sensor. Based on the received information, a movement of a portion of the sample may be determined.

Abstract: A photoelectric sensor includes a silicon substrate, a light emitter that emits first light, a light receiver that receives second light, a light emitter terminal that supplies the light emitter with electric power, and a light receiver terminal to which the light receiver outputs a signal, and the light emitter, the light receiver, the light emitter terminal, and the light receiver terminal are provided on the silicon substrate.

Abstract: The invention relates to a system for recording breathing efforts of a patient, which comprises a pressure determination device for determining a transpulmonary pressure at the point in time of the breathing effort of the patient. The invention moreover relates to a unit for recording the optimum filling volume of the balloon of an esophageal catheter.

Abstract: A head wearable unit has a shape of headphone or headband. The head wearable unit has a connector to a neural interface, a processor for processing signals received from/to be transmitted via the neural interface as well as a power supply.

Abstract: A fully-implantable brain-computer interface cyber-physical system capable of acquiring and analyzing electrocorticogram (“ECoG”) signals, recorded directly from the subdural space of the brain, to enable direct brain control of a prosthetic (e.g., a robotic gait exoskeleton or a functional electrical stimulation (“FES”) system) is disclosed. The present system comprises a plurality of electrodes, for acquiring the ECoG signals, and a digital signal processor (“DSP”) for deriving a plurality of real-time commands from the ECoG signals. These real-time commands may then be wirelessly transmitted to the prosthetic for execution. Further, to avoid wireless data transmission of the ECoG signals from the plurality of electrodes to the DSP, which would expose the brain, skull, and scalp tissue to potentially harmful radio frequencies, a subcutaneous tunneling cable operatively couples the plurality of electrodes and the DSP.

Abstract: A grip-type electrocardiographic measuring device includes a main body portion that has a spheroid shape, a plate-shaped flange portion mounted on a side surface of the main body portion, a first electrocardiographic electrode disposed at a back surface side of the main body portion and making contact with one hand when the main body portion is gripped by the one hand, and a second electrocardiographic electrode disposed on a surface of the flange portion and making contact with a finger of the other hand when the flange portion is pinched by the other hand. The flange portion has flexibility and is bendable from a mounting portion on the main body portion.

Abstract: An apparatus comprises a magnetic field detection circuit, a cardiac signal sensing circuit, a memory circuit, a control circuit, and an arrhythmia detection circuit. The cardiac signal sensing circuit generates a cardiac signal representative of cardiac activity of a subject when coupled to sensing electrodes. The control circuit is operatively coupled to the magnetic field detection circuit; the cardiac signal sensing circuit, and the memory circuit. The control circuit stores cardiac signal data determined using the sensed cardiac signal, receives an indication of magnetic field detection by the magnetic field detection circuit, stores data obtained using the sensed cardiac signal during the magnetic field detection, and stores an identifier indicating the magnetic field detection in association with the data. The arrhythmia detection circuit processes the cardiac signal data to detect a cardiac arrhythmia event and confirm the cardiac arrhythmia event according to the magnetic field indication.

Abstract: Systems and methods for managing cardiac arrhythmias are discussed. A data management system receives a first detection algorithm including a detection criterion for detecting a cardiac arrhythmia. An arrhythmia detector detects arrhythmia episodes from a physiologic signal using a second detection algorithm that is different from and has a higher sensitivity for detecting the cardiac arrhythmia than the first detection algorithm. The arrhythmia detector assigns a detection indicator to each of the detected arrhythmia episodes. The detection indicator indicates a likelihood that the detected arrhythmia episode satisfies the detection criterion of the first detection algorithm. The system prioritizes the detected arrhythmia episodes according to the assigned detection indicators, and outputs the arrhythmia episodes to a user or a process according to the episode prioritization.

Abstract: A medical device is utilized to monitor physiological parameters of a patient and capture segments of the monitored physiological parameters. The medical device includes circuitry configured to monitor one or more physiological parameters associated with the patient and an analysis module that includes a buffer and a processor. The buffer stores monitored physiological parameters and the processor analyzes the monitored physiological parameters and triggers capture of segments from the buffer in response to a triggering criteria being satisfied. The analysis module selects a pre-trigger duration based at least in part on the triggering criteria.

Abstract: The present system allows for the physician to change the relative height of the signal to allow for examination of details of the signals, while maintaining an ability to interpret signal voltage levels absolutely based on color or other secondary mechanism beyond signal height. The disclosed system and method provide for faster and more accurate analysis based upon the color of the signal. The signal height may change, such as to view, display, or examine details of the signal, while the colors of the display do not. The color scale of the signal provides an absolute scaling of the signal regardless of the displayed height.

Abstract: A system and method for ECG data classification for use in facilitating diagnosis of cardiac rhythm disorders is provided. ECG data is obtained via an electrocardiography monitor shaped for placement on a patient's chest. The ECG data is divided into segments and noise detection analysis is applied to the ECG data segments. A noise classification or a valid classification is assigned to each segment of the ECG data. At least one ECG data segment assigned the noise classification and that includes ECG data that corresponds with feedback from the patient via the electrocardiography monitor is identified. The ECG data that corresponds with the patient feedback is removed from the identified ECG data segment with the noise classification. The ECG data segments assigned the noise classification are removed from further analysis.

Abstract: An information processing apparatus includes a selection unit. The selection unit selects whether to calibrate biological information of a user in accordance with designation by the user. When the selection unit selects no calibration in accordance with designation by the user, the biological information is associated with a specific state of the user under a predetermined condition.

Abstract: An information processing apparatus includes an acquisition unit, an association unit, and a guide unit. The acquisition unit acquires biological information of a user. The association unit associates the acquired biological information with a specific state of the user. The guide unit guides the user to the specific state. A reference to be used for association with the specific state by the association unit is calibrated by using the biological information, the biological information being acquired from the user who is guided to the specific state by the guide unit.

Abstract: A wearable electrocardiography monitoring ensemble is provided. A first receptacle is defined in a wearable garment by two horizontal bands placed across the wearable garment. A second receptacle is defined by two further horizontal bands positioned across the wearable garment under the first receptacle. A first electrode assembly is positioned within the first receptacle and includes a backing with an electrical connection having an electrode on one end of the electrical connection and terminated at the other end of the electrical connection to connect with a monitor recorder. A second electrode assembly is positioned within the second receptacle and includes a backing with an electrical connection having an electrode on one end of the electrical connection and terminated at the other end of the electrical connection to connect with a further monitor recorder, wherein the first and second electrodes are aligned longitudinally in the wearable garment.

Abstract: An electrocardiograph is disclosed. A first electrocardiograph measures a first electrocardiogram waveform with a potential of a first electrode being as a reference potential among a plurality of electrodes. A second electrocardiograph measures a second electrocardiogram waveform with a potential of a second electrode being as the reference potential among the plurality of electrodes. The first electrocardiograph and the second electrocardiograph are switched in a time sharing manner, and the first electrocardiogram waveform and the second electrocardiogram waveform are measured.

Abstract: Systems and methods for improving an individual's response are disclosed. A system for improving an individual's response comprises an item of headwear having a microphone; a speaker; a recording device secured to a front of the item of headwear; an electroencephalogram cap for measuring and recording electrical activity in the individual's brain; and a computing device. The computing device includes machine readable media; an input device; an output device; a communication device for communicating over a network; a processor in data communication with the machine readable media, the input device, and the output device; and electronic instructions that, when executed by the processor, perform steps for causing the speakers to project noise to the individual and actuating the recording device to record the individual's field of view. The microphone allows the individual to communicate, over the network, with a third party.

Abstract: A wrist-wearable body composition measuring device includes a main body; a strap connected to the main body; a first input electrode and a first output electrode which are provided on an inner surface of the strap and configured to contact a wrist of a subject; a second input electrode and a second output electrode which are provided on an outer surface of the strap; a measuring unit configured to measure a body impedance of the subject by applying current to the first input electrode and the second input electrode and detecting a voltage generated between the first output electrode and the second output electrode in response to the applied current; and a processor configured to analyze a body composition of the subject based on the body impedance measured by the measuring unit.

Abstract: A device for examining limb joints comprises a support frame to which are attached mechanisms with holders for positioning patient's limbs in the region encompassing patient's hips, thighs and feet, said mechanisms being made of materials that do not interact with magnetic fields. A hip belt (B) is secured to special ports on both sides of the support frame (A) of the device, then a thigh support platform (C) is secured to the support frame on a swingable hinge, and a shank support assembly (D) is secured in the middle part, where on a common adjustment screw guided by a slider and locked in position on the support frame by means of a position nut is located a fixed casing combined with a nut and with two force measurement assemblies. A feet support assembly (E) is secured to the opposite side of the frame. The second variant of the device consists of only the following groups: the support frame (A), the thigh support platform (C) and the shank support assembly (D).

Abstract: A hydrogel sensor device can include a crosslinked hydrogel body which changes in volume in response to an environmental stimulus, a support post positioned to mechanically support the crosslinked hydrogel body during the change in volume, and a sensor positioned to detect the change in volume in the crosslinked hydrogel body.

Abstract: The present disclosure provides systems and methods for retrieving an implantable device. An implantable device includes a casing, and a marker coupled to the casing, wherein the marker includes a detectable material encased in a biocompatible material, and wherein the marker facilitates accurately locating and retrieving the implantable device after implantation in a patient.

Abstract: Systems and methods for three-dimensional imaging, modeling, mapping, and/or control capabilities in compact size suitable for integration with and/or augmentation of robotic, laparoscopic, and endoscopic surgical systems.

Abstract: A method and apparatus for determining a respiration state on the basis of a plurality of biological indicators calculated using bio-signals. The method for determining a respiration state on the basis of a plurality of biological indicators calculated using bio-signals includes collecting a photoplethysmography (PPG) signal measured by a PPG sensor and a cutaneous electric signal measured by an electrodermal activity (EDA) sensor; analyzing the collected PPG signal and cutaneous electric signal and calculating a plurality of biological indicators including a respiration rate; and comprehensively evaluating the plurality of biological indicators to determine a user's respiration state.

Abstract: A system is provided for sensing an analyte in breath of a user. The system comprises a base; a breath input operatively coupled to the base that receives the breath; a cartridge coupled to the base and in fluid communication with the breath input to receive the breath, wherein the cartridge comprises an interactant subsystem that is selected to undergo a reaction with the analyte when the analyte is present in the breath and to undergo an optical change corresponding to the reaction; and an optical subsystem coupled to the base and configured to sense the optical change, wherein the optical subsystem generates an output comprising information about the analyte in response to the optical detection.

Abstract: Provided is a compensatory movement source body region identification method including: a step of first determination that determines existence of the compensatory movement in a first motion based on whether or not first measurement data satisfies a first criterion; and/or a step of second determination that determines existence of the compensatory movement in a second motion that is of lower complicity than the first motion based on whether or not second measurement data satisfies a second criterion; and a step of identifying at least one or more body region to be the source for causing the compensatory movement based on whether or not third measurement data in a third motion that is of lower complicity than the second motion satisfies a third criterion, when determined in the step of first determination and/or the step of second determination that there is the compensatory movement.

Abstract: Methods and systems are provided for profile-based selection of imaging parameters for a clinical context. In one embodiment, a method comprises selecting a profile based on an indication of clinical context for a scan of a patient, selecting one or more sub-profiles based on the profile, selecting imaging settings for the scan based on the profile and the one or more sub-profiles, and performing the scan according to the selected imaging settings. In this way, a scan prescription may be defined more efficiently and personally for a patient while improving quality assurance and managing an x-ray radiation dose of the patient.

Abstract: A lactate working threshold-estimating device includes: an acquiring unit configured to acquire information on a gait of a person whose lactate working threshold value is to be estimated from a sensor installed on the person; and an estimating unit configured to estimate the lactate working threshold value of the person on the basis of the acquired information.

Abstract: A method for determining a rate of repetitive bodily motion of an individual with negligible contact with the individual begins by one or more computing devices transmitting a signal for reflection off of the individual and receiving a reflected signal. The method continues with one or more computing device applying a frequency estimation algorithm to the baseband signal to produce an estimated spectral density, where the estimated spectral density is in frequency domain and includes at least one frequency component corresponding to the repetitive bodily motion. The method further includes applying a repetitive bodily motion pattern search function to the estimated spectral density to estimate the rate of the repetitive bodily motion of the individual based on the at least one frequency component.

Abstract: A device for monitoring breathing activity of, e.g., athletes while exercising includes a breathing activity sensor configured to be worn by a wearer and to provide a breathing activity signal indicative of the breathing activity of the wearer. A motion sensor is configured to be worn by the wearer and to provide a motion signal indicative of the motion activity of the wearer. A processing arrangement is coupled to the breathing activity sensor to process the breathing activity signal and produce a processed breathing activity signal. The processing arrangement includes filter circuitry having a first filtering bandwidth and a second filtering bandwidth. The first filtering bandwidth is larger than the second filtering bandwidth. The filter circuitry is coupled to the motion sensor and operates with one of the first filtering bandwidth and the second filtering bandwidth selected as a function of the motion signal from the motion sensor.

Abstract: A system for monitoring medical conditions including pressure ulcers, pressure-induced ischemia and related medical conditions comprises at least one sensor adapted to detect one or more patient characteristic including at least position, orientation, temperature, acceleration, moisture, resistance, stress, heart rate, respiration rate, and blood oxygenation, a host for processing the data received from the sensors together with historical patient data to develop an assessment of patient condition and suggested course of treatment. In some embodiments, the system can further include a support surface having one or more sensors incorporated therein either in addition to sensors affixed to the patient or as an alternative thereof. The support surface is, in some embodiments, capable of responding to commands from the host for assisting in implementing a course of action for patient treatment.

Abstract: A system for recording visually guided motor activity within a bore of an MRI machine, comprising a tablet configured for mounting within the bore of the MRI machine, the tablet comprising a shielded housing, a touchscreen display mounted within the housing, and a receiver board, an interface box coupled to a controller configured to control operation of the touchscreen display, the interface box being located remotely from the bore and comprising a transmitter board for processing signals from the controller and transmitting processed signals to the receiver board of the tablet, and a cable connected between the tablet and the interface box, the cable comprising a plurality of conductors to carry signals between the receiver board and the transmitter board.

Abstract: The present invention relates to a cerebral function state evaluation device, which comprises a brain oxyhemoglobin concentration variation acquiring component, acquiring brain oxyhemoglobin concentrations of a stroke patient, who is in a phase of completing finger-nose and heel-knee-tibia tests under instruction, by applying near-infrared spectroscopic brain imaging technology; a brain functional network constructing component; a typical feature acquiring component; and an evaluation model establishing component. The cerebral function state evaluation device evaluates a patient's motor ability based on brain hemoglobin information. By using the proposed evaluation device, an evaluation result can be given only if a patient completes several required actions. The device is inventive and simple to operate, and subjective factors in the process of the scale scoring can be avoided.

Abstract: An embodiment in accordance with the present invention includes a technology to continuously measure patient mobility automatically, using sensors that capture color and depth images along with algorithms that process the data and analyze the activities of the patients and providers to assess the highest level of mobility of the patient. An algorithm according to the present invention employs the following five steps: 1) analyze individual images to locate the regions containing every person in the scene (Person Localization), 2) for each person region, assign an identity to distinguish ‘patient’ vs. ‘not patient’ (Patient Identification), 3) determine the pose of the patient, with the help of contextual information (Patient Pose Classification and Context Detection), 4) measure the degree of motion of the patient (Motion Analysis), and 5) infer the highest mobility level of the patient using the combination of pose and motion characteristics (Mobility Classification).

Abstract: Method for estimating a pure tone hearing threshold or a pure tone audiogram of a person with a non-calibrated audio-system, comprising the steps of performing a supra-threshold test at least over a portion of the audible frequency spectrum, wherein the audible frequency spectrum ranges particularly from 16 Hz to 20.

Abstract: A method comprising: conducting a hearing test for a user over a communication link established between a network entity in a communication network and a user device of a user; wherein the hearing test comprises providing audio stimuli to the user device at a plurality of test frequencies over the communication link, and monitoring responsiveness to the audio stimuli received from the user device; generating a hearing profile based on results of the hearing test; and storing the hearing profile and information associated with the user in a memory of a network entity, such that the hearing profile is available for modifying of audio signals to the user device.

Abstract: The in-vivo component measuring apparatus 1 for measuring components contained in interstitial fluid collected from a subject is provided. The apparatus includes a setting unit in which is installed an interstitial fluid collector that collects interstitial fluid, a glucose sensor for acquiring a signal reflecting the amount of the measurement target component contained in the interstitial fluid when in a state of contact with the interstitial fluid collector, and a moving unit that brings the glucose sensor into contact with the interstitial fluid collector installed in the setting unit by changing the relative position between the setting unit and the glucose sensor to a predetermined positional relationship.

Abstract: An electronic device for obtaining biometric information is provided. The electronic device includes at least one communication circuit, a first pad including a first electrode and a second electrode, the first electrode being coated with a catalyst associated with first biometric information, a second pad including at least a third electrode, and a processor for controlling the at least one communication circuit, the first pad, and the second pad. The processor is configured to obtain the first biometric information, based at least on an electric current generated by applying a specified voltage between the first electrode and the second electrode and obtain second biometric information, based at least on a voltage difference between the second electrode and the third electrode.

Abstract: A device (200) for sensing a biofluid (18) includes at least one analyte-consuming sensor (220) for measuring at least a first analyte concentration of an analyte in the biofluid (18) and at least one additional component (248). The at least one additional component (248) maintains analyte-consuming sensor (220) measurements within 20% of the first concentration measurement if a biofluid (18) sample flow rate is less than or equal to 2 times a first biofluid (18) sample flow rate measurement as measured by the device (200). A method for sensing a biofluid (18) includes measuring a first analyte concentration of an analyte in the biofluid (18) using an analyte-consuming sensor (220), measuring a first biofluid sample flow rate, and maintaining a subsequent analyte concentration measurement within 20% of the first analyte concentration measurement when a subsequently measured biofluid (18) flow rate is less than or equal to 2 times the first biofluid sample flow rate.

Abstract: A system and method for continuous glucose monitoring (CGM) of blood in a blood vessel of a patient using a non-invasive sensor composed of a patch antenna operating in the Industrial, Scientific and Medical (ISM) Radio band (5.725 GHz-5.875 GHz). The device determines the blood glucose concentration of the blood in the blood vessel based on the measured shift of the resonant frequency of the non-invasive antenna patch sensor. A radio frequency (RF) synthesizer is used to drive the patch antenna with a fraction of its output coupled to both the antenna and receiver through a directional coupler. In this approach both the transmitted (FWD) and received (REV) power are processed, by demodulating logarithmic amplifiers, which convert the RF signals to corresponding voltages for downstream processing. The resulting voltages are then fed into a microcontroller and the measured shift in resonant frequency is converted to a real-time glucose concentration.