Patents Issued in November 19, 2019
  • Patent number: 10478066
    Abstract: A system and method detects and provides alerts when a subject's physiological measurements indicate a likelihood of the presence of drug cravings and a possible return to drug use. The system includes a wearable sensor which monitors movement in three dimensions, Electro Dermal Response (EDR), and temperature. Initially, training measurements are taken while subject is under supervision and not taking drugs, and algorithms process the measurements to determine thresholds. After release from supervision, the physiological measurements are monitored, processed, and compared to the thresholds. When the comparison indicates a presence of cravings for drugs, an alert is provided to the subject and/or to monitoring personnel.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: November 19, 2019
    Inventors: Megan Reinhardt, Nicole Gilbertson
  • Patent number: 10478067
    Abstract: Procedures, implantable wireless sensing devices, and sensor assemblies suitable for monitoring physiological parameters within living bodies. Such sensor assembly includes a sensing device and an anchor for securing the sensing device within a living body. The sensing device comprises a housing having at least one internal cavity and a transducer and electrical circuitry within the at least one internal cavity. The sensing device further comprises an antenna that is within the at least one internal cavity or outside the housing. The housing has at least one additional housing portion in which the transducer, the electrical circuitry, and the antenna are not located. The anchor has a metal portion that surrounds the at least one additional housing portion so as not to surround the transducer, the electrical circuitry, or the antenna.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: November 19, 2019
    Assignee: Integrated Sensing Systems, Inc.
    Inventor: Nader Najafi
  • Patent number: 10478068
    Abstract: Camera device and method for shooting light having at least two wavelength bands are disclosed. The camera device includes a first camera containing a first lens for receiving light having a first wavelength band; a second camera including a second lens for receiving light having a second wavelength band which is different from the first wavelength band, the second lens being disposed facing the first lens of the first camera; and a parabolic mirror set between the first camera and the second camera, able to let the light having the first wavelength band penetrate therethrough, and at the same time, reflect the light having the second wavelength band. The first camera is a non-fisheye camera. The first lens is a non-fisheye lens. The second camera and the parabolic mirror form a catadioptric camera. The aperture stop of the non-fisheye lens coincides with the focal point of the parabolic mirror.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: November 19, 2019
    Assignee: Ricoh Company, Ltd.
    Inventors: Yupeng Zhang, Hong Yi, Weitao Gong, Haihua Yu, Wei Wang
  • Patent number: 10478069
    Abstract: Disclosed is a method for estimating an onset time of an infarct region based on brain images, the method including: obtaining brain images; extracting from the infarct region included in the brain images a set of quantitative values that vary according to the onset time of the infarct region; and having the set of quantitative values correspond to the onset time of the infarct region by applying a corresponding relation prepared therefor.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: November 19, 2019
    Assignee: THE ASAN FOUNDATION
    Inventors: Nam Kug Kim, Dong Wha Kang
  • Patent number: 10478070
    Abstract: An adjustable anatomy display table is disclosed. According to one embodiment, the adjustable anatomy table includes a display configured to visualize the anatomy in a real size, a base configured to support the display, and an adjustable mechanism that mechanically couples the display to the base. The adjustable mechanism is configured to adjust a position of the display relative to the base.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: November 19, 2019
    Assignee: Anatomage Inc.
    Inventors: Woncheol Choi, Kristopher Thomson, Sean Pacheco
  • Patent number: 10478071
    Abstract: A medical imaging method includes imaging a target with a hyperspectral imaging system in order to obtain imaging data. There is provided a method in medical imaging. In the method, a target is imaged with a hyperspectral imaging system in order to obtain imaging data. The obtained imaging data is pre-processed by spatial and spectral averaging. A number of endmembers to be determined from the pre-processed imaging data is selected. The endmembers are extracted from the pre-processed imaging data based on vertex component analysis on the pre-processed imaging data and the selected number of endmembers, said endmembers defining an extremity of projections of the pre-processed imaging data in a subspace spanned by the endmembers. At least one abundance map is generated of the selected number of endmembers in the pre-processed imaging data using a filter vector algorithm on the extracted endmembers and the imaging data.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: November 19, 2019
    Assignee: REVENIO RESEARCH OY
    Inventors: Noora Neittaanmäki-Perttu, Mari Grönroos, Pekka Neittaanmäki, Ilkka Pölönen, Hannu-Heikki Puupponen
  • Patent number: 10478072
    Abstract: Exemplary system, method and computer accessible medium are provided for determining at least one characteristic of a target object located behind or within a medium. For example, it is possible to identify a reference object that is located behind or within the medium. The target object and the reference object can be irradiated via a surface of the medium using at least one electromagnetic wave. At least one acoustic signal provided from an irradiated tissue volume that is responsive to the electromagnetic wave(s) can be measured. Calibration information can be obtained from the acoustic signal measured from the reference object based on at least one known property of the reference object. Then, the characteristic(s) of the target object can be determined based on the calibration information and the acoustic signal from the target object.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 19, 2019
    Assignee: The General Hospital Corporation
    Inventors: Guillermo J. Tearney, Li Li, Balachundhar Subramaniam
  • Patent number: 10478073
    Abstract: A centerline extraction unit extracts at least two coronary artery centerline structures from at least two images respectively corresponding to at least two cardiac phases concerning a heart, an interpolation processing unit interpolates coronary artery centerline structures concerning other cardiac phases from the at least two extracted coronary artery centerline structures to generate coronary artery centerline structures respectively corresponding to a plurality of cardiac phases throughout one heartbeat of the heart, and a displacement distribution calculation unit calculates a plurality of displacement distributions between the respective cardiac phases from a plurality of coronary artery centerline structures throughout the one heartbeat.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: November 19, 2019
    Assignee: Canon Medical Systems Corporation
    Inventors: Hideaki Ishii, Satoshi Wakai, Kazumasa Arakita, Takuma Igarashi, Yasuko Fujisawa, Shigeo Kaminaga, Kenji Hirohata, Junichiro Ooga
  • Patent number: 10478074
    Abstract: A system and method for determining a patient's suitability for a proposed surgical procedure is disclosed in which a simulated, procedure specific hemodynamic profile of an individual patient is obtained using a hemodynamic simulation module operating on a digital processor using a patient specific hemodynamic calculation parameter set. This is used by a trained clinician to evaluate whether the patient is a suitable candidate to undergo the proposed surgery. The patient specific hemodynamic calculation parameter set is obtained by optimizing a generic hemodynamic calculation parameter set. Optimization is done automatically by adjusting the generic hemodynamic calculation parameter set based on the comparison of simulated profiles corresponding to measured hemodynamic profiles of the patient in a non-operation situation. The automatic adjustment is guided by a Damped Least Squares Method and related algorithms.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: November 19, 2019
    Inventors: Frank Dedroog, Javier Murillo-Castarlenas, Pilar Garcia-Navarro, Adrian Navas-Montilla, Jose Ramirez-Rodriguez
  • Patent number: 10478075
    Abstract: Methods, systems, computer-readable media, and apparatuses for obtaining at least one bodily function measurement are presented. A mobile device includes an outer body sized to be portable for user, a processor contained within the outer body, and a plurality of sensors physically coupled to the outer body. The sensors are configured to obtain a first measurement indicative of blood volume and a second measurement indicative of heart electrical activity in response to a user action. A blood pressure measurement is determined based on the first measurement and the second measurement. The sensors also include electrodes where a portion of a user's body positioned between the electrodes completes a circuit and a measurement to provide at least one measure of impedance associated with the user's body. A hydration level measurement is determined based on the measure of impedance.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: November 19, 2019
    Assignee: QUALCOMM Incorporated
    Inventors: Russel Allyn Martin, Leonid Sheynblat, Douglas Wayne Hoffman
  • Patent number: 10478076
    Abstract: A device is configured to monitor a cardiovascular property of a subject. The device obtains measurement data from a primary pressure wave sensor arranged to detect pressure waves in an extracorporeal fluid circuit in fluid communication with the cardiovascular system of the subject. The device has a signal processor configured to generate a time-dependent monitoring signal based on the measurement data, such that the monitoring signal comprises a sequence of heart pulses, wherein each heart pulse represents a pressure wave originating from a heart beat in the subject; determine beat classification data for each heart pulse in the monitoring signal; and calculate, based at least partly on the beat classification data, a parameter value indicative of the cardiovascular property. The beat classification data may distinguish between heart pulses originating from normal heart beats and heart pulses originating from ectopic heart beats.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: November 19, 2019
    Assignee: Gambro Lundia AB
    Inventors: Bo Olde, Kristian Solem
  • Patent number: 10478077
    Abstract: A blood pressure meter includes a pump and a first fluid path provided inside a main body. The first fluid path feeds a fluid from the pump to a fluid bladder or discharges the fluid from the fluid bladder. A pressure sensor is mounted on a first substrate disposed inside the main body. A second fluid path that introduces the fluid from the fluid bladder to the pressure sensor is provided. The second fluid path includes an inlet pipe that is integrally formed with a sensor package that incorporates the pressure sensor, and extends straight between the fluid bladder and the pressure sensor. A second substrate on which a blood pressure measurement element is mounted is disposed in a space that is located between the first substrate and the fluid bladder in a thickness direction and is adjacent to the second fluid path in a planar direction.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: November 19, 2019
    Assignee: OMRON HEALTHCARE Co., Ltd.
    Inventors: Kenji Ono, Yuma Adachi, Yoshihide Tokko, Eisuke Yamazaki
  • Patent number: 10478078
    Abstract: The present invention relates to a Device for determining vital signs of a subject comprising an interface (22) for receiving a periodic photoplethysmographic, PPG, signal obtained from a subject (14) by a PPG measurement, a signal partitioning unit (24) for partitioning the PPG signal in time into a plurality of PPG sub-signals covering a half period or an integer multiple of a half period, a normalizing unit (26) for normalizing the PPG signal in advance of the partitioning and/or the PPG sub-signals in time and/or amplitude, a signal combination unit (28) for combining a number of normalized PPG sub-signals to obtain a combined PPG sub-signal, and a vital sign processor (30) for deriving a desired vital sign from the PPG signal, one or more combined PPG sub-signals or an enhanced PPG signal obtained by consecutively arranging a number of combined PPG sub-signals.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: November 19, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Gerard De Haan
  • Patent number: 10478079
    Abstract: A pulse can be stably estimated based on an image data suitable for extracting a pulse signal. A pulse estimation device includes image input portion (21) to which time-sequential captured images including at least a portion of subject H as an object are input from camera (2); region extractor (22) that extracts a skin-color region from each of the captured images; zoom commander (28) that transmits a zoom command to camera (2) that has imaged the captured images or a user of camera (2) in order to adjust a size of the skin-color region; and pulse estimator (23) that estimates a pulse of subject H based on the skin-color region of the captured images obtained by imaging with camera (2), after the zoom command is transmitted.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: November 19, 2019
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Tadanori Tezuka, Tsuyoshi Nakamura, Masatoshi Matsuo
  • Patent number: 10478080
    Abstract: A physiological detection system including an array sensor and a processing unit is provided. The array sensor is configured to output array PPG signals. The processing unit is configured to construct a 3D energy distribution according to the array PPG signals to accordingly identify different microcirculation states.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: November 19, 2019
    Assignee: PIXART IMAGING INC.
    Inventors: Wei-Ru Han, Chih-Yuan Chuang, Cheng-Nan Tsai, Ren-Hau Gu
  • Patent number: 10478081
    Abstract: The present invention relates to a decision support system (DSS), a medical monitoring system (100), and a corresponding method for identifying the need for measurement of cardiac output (CO) based on one or more comparisons (COMP1, COMP2) in a physiological model. More specifically, for identifying when an approximated value of CO cannot be correct due to circulatory compromise and as such that another estimated or measured value of CO is required.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: November 19, 2019
    Assignee: Mermaid Care A/S
    Inventors: Stephen Edward Rees, Dan Stieper Karbing
  • Patent number: 10478082
    Abstract: Provided is a film-type biomedical signal measuring apparatus configured in a such a way that a plurality of metallic thin film electrodes and a circuit unit are formed on a film-type piezoelectric element so as to easily attach the apparatus to the skin and an electrical signal as well as an electrical signal of a human body is simultaneously measured using the plurality of metallic thin film electrodes and the circuit unit. Accordingly, the film-type biomedical signal measuring apparatus simultaneously measures electrocardiogram (ECG) and ballistocardiogram (BCG) from the simultaneously measured electrical signal and vibration signal of the human body and extracts biomedical information of various types of health indexes such as a heart rate, a stress index, BCG, a blood pressure, an amount of physical activity, a respiration rate, and VO2max from the two different biomedical signals.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: November 19, 2019
    Assignee: Seoul National University R&DB FOUNDATION
    Inventors: Hee Chan Kim, Seung Woo Noh, Chi Yul Yoon
  • Patent number: 10478083
    Abstract: Physiological monitoring can be provided through a wearable monitor that includes two components, a flexible extended wear electrode patch and a removable reusable monitor recorder. The wearable monitor sits centrally (in the midline) on the patient's chest along the sternum oriented top-to-bottom. The placement of the wearable monitor in a location at the sternal midline (or immediately to either side of the sternum) benefits extended wear by removing the requirement that ECG electrodes be continually placed in the same spots on the skin throughout the monitoring period. Instead, the patient can place an electrode patch anywhere within the general region of the sternum. Power is provided through a battery provided on the electrode patch, which avoids having to open the monitor recorder's housing for battery replacement.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: November 19, 2019
    Assignee: Bardy Diagnostics, Inc.
    Inventors: Jason Felix, Jon Mikalson Bishay, Gust H. Bardy
  • Patent number: 10478084
    Abstract: Apparatuses and methods for extracting, de-noising, and analyzing electrocardiogram signals. Any of the apparatuses described herein may be implemented as a (or as part of a) computerized system. For example, described herein are apparatuses and methods of using them or performing the methods, for extracting and/or de-noising ECG signals from a starting signal. Also described herein are apparatuses and methods for analyzing an ECG signal, for example, to generate one or more indicators or markers of cardiac fitness, including in particular indicators of atrial fibrillation. Described herein are apparatuses and method for determining if a patient is experiencing a cardiac event, such as an arrhythmia.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: November 19, 2019
    Assignee: AliveCor, Inc.
    Inventors: Conner Daniel Cross Galloway, David E. Albert
  • Patent number: 10478085
    Abstract: The present disclosure provides an apparatus including: one or more needle-like bases enabled to be inserted into the brain; a first electrode having a first impedance and enabling an input of an electric activity of a nucleus with which the first electrode comes into contact; and a second electrode having a second impedance lower than the first impedance and being able to output an electric stimulation to the nucleus, wherein the first electrode is provided at a tip portion of at least one of the bases, and the second electrode is provided on a part of the at least one of the bases at a position identical to a position of at least one of the first electrode or on a proximal side with respect to the first electrode, in a direction along a long axis of the base on which the first electrode is provided.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: November 19, 2019
    Assignee: INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES
    Inventors: Atsushi Nambu, Satomi Chiken, Yukio Nishimura, Sayuki Takara
  • Patent number: 10478086
    Abstract: The present invention includes a responsive neural stimulator having electrodes, a filter, a processor, a recording medium, an extractor for extracting instantaneous voltage amplitudes of biased oscillatory activity with asymmetrically distributed peak/trough amplitudes, and a neural stimulator connected to the processor configured to apply neural stimulation via the neural stimulator when a predetermined state of neuronal excitability is detected, a state of relatively higher neuronal excitability corresponding to a relatively lower instantaneous voltage amplitude extracted by the extractor.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: November 19, 2019
    Assignee: HEALTH RESEARCH, INC.
    Inventors: Gerwin Schalk, Peter Brunner, William G. Coon, Adriana De Pesters
  • Patent number: 10478087
    Abstract: An open bore coil system enabling electronic steering and rotation of a Field Free Line (FFL) inside a large volume. An FFL is generated by placing two parallel coil pairs (fed with alternating current directions) side by side. Using two of these coil groups, the FFL can be rotated in the plane perpendicular to the coil axes. The FFL can be translated in the rotation plane of the FFL using a coil pair placed on the same axis with the other coils. It can also be translated in the perpendicular plane by asymmetrical coil excitation. As all the coils in the system are parallel, the imaged object can be reached from the sides during imaging.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: November 19, 2019
    Assignee: ASELSAN ELEKTRONIK SANAYI VE TICARET A.S.
    Inventors: Can Baris Top, Huseyin Emre Guven
  • Patent number: 10478088
    Abstract: A pack of disposable multi-layered liner sheets suitable for covering non-planar surfaces of medical scanners having a long, hard to clean, bore or tunnel, particularly MRI scanners, to establish a sterile patient environment. Liner sheets are connected end-to-end in a stack by an adhesive or a linear array of perforations to respective succeeding and preceding sheets of the pack. In one embodiment, the pack is secured inside the bore by pegs on the top side of the pack engaging strategically placed clips attached to the bore wall. In other embodiments, the pack is secured inside the bore by opposing sides of a backing layer extending laterally beyond the liner sheets to engage a groove in guide rails affixed inside the bore.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 19, 2019
    Inventor: Michael F. Fink
  • Patent number: 10478089
    Abstract: Disclosed herein is a method for capturing a dental object with an object volume, in particular, at least one part of a maxilla and/or a mandible, with the sue of an MRT apparatus. A plurality of MRT segment images, which depict the defined segmented volume regions are acquired by an MRT apparatus within a measurement volume of the MRT apparatus. The segmented volume regions overlap no more than partially. In this case a target surface is defined or has already been defined. Then a two dimensional composite image, which corresponds to a two dimensional aggregate image through the target surface within the object volume of the dental object, is generated computer-aided from the individual MRT segment images.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: November 19, 2019
    Assignee: DENTSPLY SIRONA Inc.
    Inventors: Ciamak Abkai, Tim Braun, Jan Paul, Volker Rasche
  • Patent number: 10478090
    Abstract: A magnetic resonance imaging (MRI) system can include a magnetic resonance imaging (MRI) scanner, having a plurality of radio frequency (RF) receivers, and a processor. The MRI scanner can perform a full field of view (fFOV) scan on an anatomy area including an implant to acquire first multi-spectral MRI data associated with a plurality of frequency bins. The processor can generate, for each pair of a single RF receiver and a single frequency bin, a respective spectral sensitivity map using at least a portion of the fFOV multi-spectral MRI data. The MRI scanner can perform a reduced FOV (rFOV) scan to acquire second multi-spectral MRI data associated with the plurality of frequency bins. The processor can reconstruct one or more MRI images according to the rFOV using the rFOV multi-spectral MRI data and the spectral sensitivity maps.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: November 19, 2019
    Assignee: Medical College of Wisconsin
    Inventors: Kevin Matthew Koch, Andrew Scott Nencka
  • Patent number: 10478091
    Abstract: Provided is a micro robot position detection device. The device includes a micro robot position detection unit that uses a micro robot control parameter to filter a reflected signal of an ultra wide-band impulse radar signal emitted to a micro robot to extract, as a micro robot signal, a natural oscillating frequency signal generated when the micro robot is driven through control of external electromagnetic field, and analyzes the micro robot signal based on a transmission and reception parameter of the ultra wide-band impulse radar signal to calculate position information for the micro robot. Also, the device may further include an image matching unit that receives position information for the micro robot and performs position correction on the received position information based on pre-stored reference image data and the image data.
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: November 19, 2019
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Hong Yeon Yu, Nac Woo Kim, Sim-Kwon Yoon, Byung-Tak Lee, Young Sun Kim
  • Patent number: 10478092
    Abstract: A registration method whereby a sensor-based approach is used to establish initial registration and whereby upon the commencement of navigating an endoscope, image-based registration methods are used in order to more accurately maintain the registration between the endoscope location and previously-acquired images. A six-degree-of-freedom location sensor is placed on the probe in order to reduce the number of previously-acquired images that must be compared to a real-time image obtained from the endoscope.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: November 19, 2019
    Assignee: Covidien LP
    Inventors: Dorian Averbuch, Oded Zur, Oren P. Weingarten
  • Patent number: 10478093
    Abstract: To provide an exhaled-air pressure measuring device capable of deciding on exhaled-air pressure levels suitable for usage purposes. An exhaled-air pressure measuring device measures the pressure of air exhaled by a user, and on the basis of the measurement result, decides on an exhaled-air pressure level which corresponds to the pressure of the exhaled air. The exhaled-air pressure measuring device includes a measuring device body, and a mouthpiece portion from which the user exhales into the device. The measuring device body includes: a microcomputer which stores threshold data representing a threshold of the exhaled-air pressure level and decides on the exhaled-air pressure level corresponding to the exhaled-air pressure of a detection signal detected by a pressure sensor; and a USB terminal which is connected to an external storage device so as to change the threshold data stored in the microcomputer.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: November 19, 2019
    Assignee: YUBA CORPORATION
    Inventor: Tasuku Yuba
  • Patent number: 10478094
    Abstract: A ketone measurement and analysis system provides various features for enabling health program participants to interpret their ketone measurements, such as breath acetone measurements. One such feature breaks down ketone measurements into causal components. For example, the system may generate and display an estimate of how much of a participant's ketone measurement is attributable to stored fat metabolism versus consumption of a “confounding substance” such as dietary fat and/or exogenous ketones. The system may also estimate the contributions of specific confounding substances, and/or the contributions of other factors or events (such as exercise, interrupted sleep, a missed medication, etc.) that affect ketone levels. Another feature involves the generation and display of target ketone levels that are personalized for the participants. The system may generate the measurement breakdowns and target ketone levels by applying data mining algorithms to aggregated data of many program participants.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 19, 2019
    Assignee: Invoy Holdings, LLC
    Inventor: Lubna M. Ahmad
  • Patent number: 10478095
    Abstract: The present invention relates to analyzing fatigue level of users by transmitting pressure data from user's shoes wirelessly for real-time monitoring. Athletes for in body-contact games such as football, are often suddenly forced out of games due to injuries as it is often difficult to ascertain the nature of the injury on the field. The present invention enables a coach to have an ability to monitor performance of the athletes as they play, thus help in determining current level of athlete's injury, and help in preventing career threatening and/or fatal injuries. Further, pressure sensors can be used to determine fatigue detection and can be verified by readings from knock sensor, accelerometer data, etc. Variations in all such sensors for a time slice t-seconds can be used as an indicator for fatigue.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: November 19, 2019
    Inventor: Dharma P Agrawal
  • Patent number: 10478096
    Abstract: A neural monitoring system for detecting an artificially-induced mechanical muscle response to an electrical stimulus at a stimulation frequency includes a mechanical sensor and a processor in communication with the mechanical sensor. The mechanical sensor is configured to be placed in mechanical communication with the muscle and to generate a mechanomyography output signal corresponding to a sensed mechanical movement of the muscle. The processor is configured to receive the mechanomyography output signal from the mechanical sensor and determine a frequency component of the mechanomyography output signal that has a peak magnitude and to detect the occurrence of an artificially-induced mechanical muscle response therefrom.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: November 19, 2019
    Assignee: Innovative Surgical Solutions.
    Inventors: Christopher Wybo, Darren Scarfe, Aashish Shah
  • Patent number: 10478097
    Abstract: A neural monitoring system for detecting an artificially-induced mechanical muscle response to a stimulus provided within an intracorporeal treatment area includes a mechanical sensor and a processor in communication with the mechanical sensor. The mechanical sensor is configured to be placed in mechanical communication with the muscle and to generate a mechanomyography output signal corresponding to a sensed mechanical movement of the muscle. The processor is configured to receive the mechanomyography output signal from the mechanical sensor and determine a frequency component of the mechanomyography output signal that has a peak magnitude and to detect the occurrence of an artificially-induced mechanical muscle response therefrom.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: November 19, 2019
    Assignee: Innovative Surgical Solutions
    Inventors: Christopher Wybo, Darren Scarfe, Aashish Shah
  • Patent number: 10478098
    Abstract: An information processing system includes: a sheet that is usable in a use mode which is any one of an underlay mode and a cover mode; an accumulation unit that accumulates relevant information related to when the sheet is used in association with the use mode of the sheet when being used; and a presentation unit that presents a result of analysis of the information accumulated in the accumulation unit, in consideration of the use mode.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: November 19, 2019
    Assignee: FUJI XEROX CO., LTD.
    Inventors: Mizuha Marumoto, Yukari Sai, Yuka Nomura, Yukiko Miyakoshi, Kengo Tokuchi
  • Patent number: 10478099
    Abstract: This relates to systems and methods for determining the axial orientation and location of the user's wrist using one or more sensors located on the strap, the device underbody, or both. For example, the strap can include a plurality of elastic sections and a plurality of rigid sections. Each elastic section can include one or more flex sensors. In some examples, on or more electromyography (EMG) sensors can be included to measure the user's electrical signals, and the user's muscle activity can be determined. In some examples, a plurality of strain gauges can be included to generate one or more signals indicative of any changes in shape, size, and/or physical properties of the user's wrist. In some examples, the device can include a plurality of capacitance sensors for increased granularity and/or sensitivity in measuring the amount of tension exerted by the user's wrist.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 19, 2019
    Assignee: Apple Inc.
    Inventors: Jason Lor, Siddharth Nangia
  • Patent number: 10478100
    Abstract: A medical device and a method for configuring a process for determining a dose of insulin to be administered for glycemic control is provided, wherein the dose is stepwise adapted, comprising defining different dose adjustment profiles for stepwise adapting the dose, wherein each of the different dose adjustment profiles is based at least on a specific initial dose value, a specific time interval for increasing the dose, a specific dose increase step and a specific low blood glucose threshold value, storing the different dose adjustment profiles, selecting one of the stored different dose adjustment profiles based on specific requirements for stepwise adapting the dose, and personalizing the selected dose adjustment profile by defining at least a specific target blood glucose value for a specific user.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: November 19, 2019
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Andrew Tubb
  • Patent number: 10478101
    Abstract: A passive sensing continuous glucose monitoring system and method of use thereof. The system includes a passive antenna formed of biocompatible silicon carbide (SiC), modeled to a desired frequency, which is permanently implanted subcutaneously. The system further includes an external-to-the-body transmitting antenna to detect changes in the blood glucose level by sending a radio signal at the frequency of the implanted passive antenna into the body. This signal is received and reflected by the passive antenna, and the reflected signal is then received at an external-to-the-body receiving antenna. Changes in the glucose level lead to modifications in the signal and can be used to determine the blood glucose level externally.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: November 19, 2019
    Assignee: University of South Florida
    Inventors: Fabiola Araujo Cespedes, Stephen E. Saddow, Christopher Leroy Frewin, Erdem Topsakal
  • Patent number: 10478102
    Abstract: An introducer is provided for introducing a sensor into the body of a patient. The introducer connects to a sensor hub. When the sensor hub and introducer are connected, the introducer needle is exposed. When the sensor hub and introducer are disconnected, a needle cover and the needle move with respect to each other so that the needle cover substantially covers the needle, protecting a user from being injured by the needle.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: November 19, 2019
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Rebecca K. Gottlieb, Rajiv Shah, Katherine T. Wolfe, Eric Allan Larson
  • Patent number: 10478103
    Abstract: Embodiments of the invention provide apparatus, systems, and methods wherein pre-event and post-event analyte concentration readings associated with an event are collected and processed to determine a numerical delta. The numerical delta may be displayed on a visual display to aid in a ready determination of the affect that the event (alone or in combination with medication and/or insulin dosages) had on the analyte concentration levels. Medication and/or insulin dosages may be displayed alongside the numerical delta to gauge immediate relationships between numerical delta, dosage, and/or an associated event. Apparatus and systems for calculating and displaying the numerical delta are described, as are other aspects.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: November 19, 2019
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: David A. Simmons, Jeffery S. Reynolds, Paul M. Ripley, Stanley A. Telson
  • Patent number: 10478104
    Abstract: A contact lens includes a glucose sensor which can determine when a detectable concentration of glucose is present in the optical fluids of the user. The glucose sensor can transition between a first state and a second state relative to the concentration of glucose within the optical fluid of the user. The glucose sensor can be bonded or otherwise attached or incorporated into the contact lens. While the contact lens is worn in the user's eye, either the user or another person can view the contact lens to quickly determine if an excessive amount of glucose is present in the user's system.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: November 19, 2019
    Assignee: MENICON CO., LTD.
    Inventor: Mouad Lamrani
  • Patent number: 10478105
    Abstract: An extracorporeal blood circulation management device having an oxygenator accurately determines oxygen consumption by the target person and oxygen delivery by the oxygenator. Oxygenation-related parameter values in the blood are determined at regular intervals. An in-body passing time (a cycle time for a particular volume of blood to pass from input sensors to output sensors) is determined. Parameter values separated by the in-body passing time are selected as comparison targets to evaluate oxygenation consumption of the target person. An oxygenator unit passing time is determined. Parameter values separated by the oxygenator unit passing time are selected as comparison targets to evaluate oxygenation delivery of the oxygenation unit.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: November 19, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Tomoki Utsugida, Tomoaki Hashimoto, Tsuyoshi Hasegawa
  • Patent number: 10478106
    Abstract: The present disclosure concerns a measuring probe (10) for non-invasive in vivo measurement of blood analytes (33) by Raman spectroscopy. The measuring probe (10) comprises a housing (20) having a skin engaging surface (21). The housing (20) comprises a first optical system (1, 3, 4) arranged for providing source light (11) to the skin engaging surface (21) for penetrating a subject's skin (31) by said source light (11) for interacting with the blood analytes (33). The housing (20) further comprises a second optical system (5, 6, 2) arranged for capturing scattered Raman light (12) from the blood analytes (33) for measurement of the blood analytes (33). The first optical system (1, 3, 4) is arranged for providing the source light (11) as a collimated beam (1c) onto the skin (31).
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: November 19, 2019
    Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO
    Inventors: Daniel Perez Calero, James Peter Robert Day, Jacobus Thomas Wilhelmus Elisabeth Vogels, Maarten J. Scholtes-Timmerman, Jacobus Johannes Frederik van Veen
  • Patent number: 10478107
    Abstract: A sensor cover according to embodiments of the disclosure is capable of being used with a non-invasive physiological sensor, such as a pulse oximetry sensor. Certain embodiments of the sensor cover reduce or eliminate false readings from the sensor when the sensor is not in use, for example, by blocking a light detecting component of a pulse oximeter sensor when the pulse oximeter sensor is active but not in use. Further, embodiments of the sensor cover can prevent damage to the sensor. Additionally, embodiments of the sensor cover prevent contamination of the sensor.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: November 19, 2019
    Assignee: Masimo Corporation
    Inventors: Abraham Mazda Kiani, Massi Joe E. Kiani
  • Patent number: 10478108
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: November 19, 2019
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Howard Wolpert, Adam Heller
  • Patent number: 10478109
    Abstract: A fluid transfer device for parenterally transferring fluid to and/or from a patient includes a housing, a needle, and an occlusion mechanism. The housing defines a fluid flow path and is couplable to a fluid reservoir. The needle has a distal end portion that is configured to be inserted into the patient and a proximal end portion that is configured to be fluidically coupled to the fluid flow path of the housing, and defines a lumen therebetween. The occlusion mechanism selectively controls a fluid flow between the needle and the fluid flow path. The occlusion mechanism includes an occlusion member that is movable between a first configuration where the lumen of the needle is obstructed during insertion into the patient and a second configuration where the lumen of the needle is unobstructed after the needle has been inserted into the patient allowing fluid transfer to or from the patient.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: November 19, 2019
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Jay M. Miazga, Shan E. Gaw, Richard G. Patton
  • Patent number: 10478110
    Abstract: A social intimacy determining method includes detecting electrocardiogram (ECG) data from at least two subjects; detecting heart rhythm pattern (HRP) data from ECG signals of the two subjects; and determining a relationship (intimacy) between the two subjects by comparing the HRP data of the two subjects.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: November 19, 2019
    Assignees: SANGMYUNG UNIVERSITY SEOUL INDUSTRY—ACADEMY COOPERATION FOUNDATION, CENTER OF HUMAN-CENTERED INTERACTION FOR COEXISTENCE
    Inventors: Sang In Park, Min Cheol Whang, Myoung Ju Won, Sung Teac Hwang
  • Patent number: 10478111
    Abstract: A computer-implemented method can include a speech collection module collecting a speech pattern from a patient, a speech feature computation module computing at least one speech feature from the collected speech pattern, a mental health determination module determining a state-of-mind of the patient based at least in part on the at least one computed speech feature, and an output module providing an indication of a diagnosis with regard to a possibility that the patient is suffering from a certain condition such as depression or Post-Traumatic Stress Disorder (PTSD).
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: November 19, 2019
    Assignee: SRI International
    Inventors: Bruce Knoth, Dimitra Vergyri, Elizabeth Shriberg, Vikramjit Mitra, Mitchell McLaren, Andreas Kathol, Colleen Richey, Martin Graciarena
  • Patent number: 10478112
    Abstract: A computer system for generating a diagnostic tool by applying artificial intelligence to an instrument for diagnosis of a disorder, such as autism. For autism, the instrument can be a caregiver-directed set of questions designed for an autism classification tool or an observation of the subject in a video, video conference, or in person and associated set of questions about behavior that are designed for use in a separate autism classification tool. The computer system can have one or more processors and memory to store one or more computer programs having instructions for generating a highly statistically accurate set of diagnostic items selected from the instrument, which are tested against a first test using a technique using artificial intelligence and a second test against an independent source. Also, a computer implemented method and a non-transitory computer-readable storage medium are disclosed.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: November 19, 2019
    Assignee: President and Fellows of Harvard College
    Inventor: Dennis Wall
  • Patent number: 10478113
    Abstract: The present disclosure relates generally to using detected bladder events for the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction. A system includes a sensing device comprising a pressure sensor to directly detect a pressure within a bladder. The sensing device is adapted to be located within the bladder. The system also includes a signal processing device to: receive a signal indicating the detected pressure within the bladder; detect a bladder event based the detected pressure within the signal; and characterize the bladder event as a bladder contraction event or a non-contraction event. The characterization of the bladder event can be used in the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: November 19, 2019
    Assignees: THE CLEVELAND CLINIC FOUNDATION, CASE WESTERN RESERVE UNIVERSITY, THE U.S. GOV'T AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS
    Inventors: Margot S. Damaser, Swarup Bhunia, Robert Karam, Steve Majerus, Dennis Bourbeau, Hui Zhu
  • Patent number: 10478114
    Abstract: A brain dysfunction assessment device (100) comprises: a body movement indicator (10) which presents a body movement to be performed to a subject with a body movement presentation device (2); a body movement data acquisition unit (20) which acquires the subject's body movement data with a body movement detection sensor (3); a body movement accuracy calculation unit (30) which calculates a positional accuracy and a time sequence accuracy of the subject's body movement from the acquired body movement data; and a cognitive dysfunction assessment unit (40) which assesses the level of cognitive dysfunction of the subject by comparing a value which indicates the accuracy of the subject's body movement that is obtained from the calculated positional accuracy and time sequence accuracy with statistical data which indicates the accuracy of body movement of healthy individuals.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: November 19, 2019
    Assignee: MAXELL, LTD.
    Inventors: Yuko Sano, Akihiko Kandori, Kanako Esaki, Kazuhiro Kaizaki, Shinya Katsuki, Kenji Katsumata, Tomohiko Mizuguchi, Yasushi Saito, Tamotsu Nagabayashi, Tomochika Yamashita, Takumi Okamura
  • Patent number: 10478115
    Abstract: Light weight personal handheld home monitoring and managing device, which includes a Sound Sensor network/array of Sound Sensor networks combined with an Artificial Neural Network (ANN) and a build in system and methods, making this device an intelligent and portable apparatus to address specific health issues. The combined apparatus is used for managing and/or guidance and/or diagnosing and/or controlling and managing purposes. This present version of the apparatus will address pulmonary disorders and diseases or similar ailments.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: November 19, 2019
    Assignee: SpiroFriend Technology ApS
    Inventor: Dan Avrahamson