Patents Issued in March 19, 2020
  • Publication number: 20200086000
    Abstract: The described invention provides soft tissue grafts, hard tissue grafts, and composite soft/hard tissue grafts and methods of producing such grafts. The grafts comprise a three-dimensional carrier matrix, a growth factor composition comprising an autologous platelet-rich fibrin and a cell culture composition comprising a culture medium, a population of cells suspended in the culture medium, and cells impregnated on or in a surface of osteoconductive particles.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 19, 2020
    Inventors: Nicholas ELIAN, Sean M. O'CONNELL, William K. BOSS, JR.
  • Publication number: 20200086001
    Abstract: Periosteum harvesting and processing systems and methods enable rapid, efficient, and repeatable harvesting of periosteum tissue from human long bones and processing of the tissue into individual fibers for use in strengthening surgical allograft products. One harvesting and processing method involves providing a human long bone, securing the long bone between two rotating live centers, scraping, using one of a plurality of harvesting tools selected from a harvesting and processing kit, periosteum tissue from the long bone, executing a first wash cycle comprising a hydrogen peroxide wash, executing a second wash cycle comprising an isopropyl alcohol wash, executing a third wash cycle comprising a phosphate buffered saline wash, compressing the periosteum tissue to remove excess fluid, cryofracturing the tissue until a desired fiber size is achieved, and separating the periosteum tissue into individual periosteum fibers having the desired fiber size. Other embodiments are also disclosed.
    Type: Application
    Filed: September 16, 2019
    Publication date: March 19, 2020
    Inventors: Megan Maccagnan, Cameron Mattson, Cole Watkins, Adrian C. Samaniego, William Maslanik
  • Publication number: 20200086002
    Abstract: Described herein are bioengineered constructs and methods of producing the same. The constructs and methods disclosed herein can be applied towards, for example, the generation of vascular grafts to treat cardiovascular disease.
    Type: Application
    Filed: September 13, 2019
    Publication date: March 19, 2020
    Inventor: Khatija Pinky ALI
  • Publication number: 20200086003
    Abstract: A method for decellularization of a skin tissue according to an embodiment of the present invention comprises: a step of preparing a skin tissue to be decellularized; a peeling preparation step of treating the skin tissue with a first solution containing trypsin; and a peeling step of removing subcutaneous fat from the skin tissue after the peeling preparation step.
    Type: Application
    Filed: May 25, 2018
    Publication date: March 19, 2020
    Inventors: Dong Woo CHO, Jeong Sik KONG, Byoung Soo KIM
  • Publication number: 20200086004
    Abstract: The invention provides cellular compositions that contain CD34+ cells derived from bone marrow of a decease donor and CD3+ cells derived from non-bone marrow of the deceased donor. The compositions are useful to promote mixed chimerism in recipients of solid organ transplants. The invention also provides methods of making and using such compositions. In certain embodiments, the invention further provides methods of analyzing and preparing blood and blood components from a deceased donor for use in compositions of the invention to promote mixed chimerism in solid organ transplant recipients.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 19, 2020
    Inventors: Michael Zdanowski, Colby Suire, D. Scott Batty, JR.
  • Publication number: 20200086005
    Abstract: The invention relates to implantable systems for repairing and restoring cartilage. The invention provides methods and products for cartilage repair that use universal chondrocytes. A universal cell line includes cells such as universal chondrocytes that are not immunogenic or allergenic and can be grown in products suitable for use in a number of different people. Use of the universal chondrocytes allows for new processes and products. Where prior art autologous neocartilage constructs required many small reactors (e.g., at least one culture dish per patient to grow one 34 mm disc per patient), using a universal cell line allows, for example, one large batch of cartilage or neocartilage to be made under uniform conditions.
    Type: Application
    Filed: April 25, 2019
    Publication date: March 19, 2020
    Applicant: HISTOGENICS CORPORATION
    Inventor: Stephen Richard Kennedy
  • Publication number: 20200086006
    Abstract: The invention provides cellular compositions that contain CD34+ cells derived from bone marrow of a decease donor and CD3+ cells derived from non-bone marrow of the deceased donor. The compositions are useful to promote mixed chimerism in recipients of solid organ transplants. The invention also provides methods of making and using such compositions. In certain embodiments, the invention further provides methods of analyzing and preparing blood and blood components from a deceased donor for use in compositions of the invention to promote mixed chimerism in solid organ transplant recipients.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 19, 2020
    Inventors: Michael Zdanowski, Colby Suire, D. Scott Batty, JR.
  • Publication number: 20200086007
    Abstract: Provided herein are human arterial endothelial cell-seeded polymeric vascular grafts suitable for replacing or bypassing natural blood vessels and exhibiting increased long term patency rates and reduced leukocyte adhesion relative to grafts comprising venous endothelial cells. Methods for generating the human arterial endothelial cell-seeded vascular grafts and therapeutic uses of the same are also described.
    Type: Application
    Filed: August 30, 2019
    Publication date: March 19, 2020
    Inventors: James A. Thomson, Jue Zhang
  • Publication number: 20200086008
    Abstract: A lubricating coating including at least one polymer A, a cross-linker and at least one lubricating agent, and wherein a portion of the at least two reactive groups of the cross-linker are covalently linked to the polymer A to form a three-dimensional network in which the lubricant is incorporated, and wherein at the same time another portion of the reactive groups of the cross-linker are covalently linked to the surface of the device or to the optional adhesion layer on the surface of the device.
    Type: Application
    Filed: May 30, 2017
    Publication date: March 19, 2020
    Applicant: SUSOS AG
    Inventors: Samuele TOSATTI, Olof STERNER, Stefan ZUERCHER, Christian MATHIS
  • Publication number: 20200086009
    Abstract: Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventor: Pierre F. LEBRETON
  • Publication number: 20200086010
    Abstract: Systems and methods for biofilm inoculation including a feeding tube having a distal end for placement in the gut of a patient, and a biofilm coated or otherwise provided on the distal end of the feeding tube for introducing the biofilm to the gut of the patient. In example embodiments, the biofilm can be colostrum, breast milk or one or more probiotics.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 19, 2020
    Applicant: NeoMed, Inc.
    Inventor: Aaron N. INGRAM
  • Publication number: 20200086011
    Abstract: An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Duncan J. Maitland, Todd L. Landsman, John Horn, Landon Nash, Chung Yeh
  • Publication number: 20200086012
    Abstract: The present invention discloses a compound heparin anticoagulant coating liquid, a microsphere for coating and its preparation methods and applications. In the present invention, the combination of curcumin and heparin can enhance the anticoagulation functions of heparin coating, and further enhance the stability using the properties of PLA-PEG-PLA drug-loaded sustained-release microspheres, achieving the functions of anti-tissue proliferation and anti-inflammatory reactions that cannot be achieved by coatings alone such as heparin or protein, which is very important for implanted devices such as artificial blood vessels, vascular stents and vascular patches to reduce thrombosis in the human body, lower postoperative complications and improve product lifespan.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 19, 2020
    Inventors: TUO YAN, CHENXI OUYANG, YAWEN LIU, SISHI LIU, YUAN LIU
  • Publication number: 20200086013
    Abstract: Embodiments of negative pressure wound therapy systems and methods are disclosed. In one embodiment, a system includes a wound dressing, negative pressure source, switch, and control circuitry. The switch can include an actuator that toggles states of first and second pairs of contacts in response to a user input. The control circuitry can supply negative pressure with the negative pressure source when the state of the first pair of contacts is a first state and the state of the second pair of contacts is a second state, and the control circuitry can disable supply of negative pressure with the negative pressure source when the state of the first pair of contacts is not the first state or the state of the second pair of contacts is not the second state.
    Type: Application
    Filed: May 4, 2018
    Publication date: March 19, 2020
    Inventor: Felix Clarence Quintanar
  • Publication number: 20200086014
    Abstract: A negative pressure wound therapy system includes a dressing, a tube, a flow restriction pad, and an in-line filter. The dressing is configured for placement in a wound bed. The tube includes a first end and a second end. The first end is configured to be operably coupled to the dressing. The second end is configured to engage a negative pressure source. The flow restriction pad is configured to be coupled to the dressing proximate the first end of the tube. The flow restriction pad includes a tortuous fluid flow path that is configured to restrict or reduce an amount of a fluid drawn from the dressing into the tube and induce a backpressure between the dressing and the tube. The in-line filter is positioned within the tube between the first end and the second end. The in-line filter configured to substantially prevent the fluid entering the tube.
    Type: Application
    Filed: September 13, 2019
    Publication date: March 19, 2020
    Inventors: Christopher B. Locke, Timothy M. Robinson
  • Publication number: 20200086015
    Abstract: A negative pressure wound treatment (NPWT) system including a NWPT therapy unit and a wound dressing configured to overlay a wound bed. The NPWT system includes a first length of tubing comprising a first end and a second end, the first end of the first length of tubing coupled to the NWPT therapy unit and the second end of the first length of tubing having a first coupling half, as well as a second length of tubing having a first end and second end, the first end of the second length of tubing coupled to the wound dressing and the second end of the second length of tubing having a second coupling half. The NPWT system includes an inline filter comprising a sintered polymer and a superabsorbent material, and an inline coupling, wherein the inline coupling is configured to operably couple and de-couple the NPWT therapy unit and wound dressing.
    Type: Application
    Filed: September 13, 2019
    Publication date: March 19, 2020
    Inventors: Timothy Mark Robinson, Christopher Brian Locke, Colin John Hall
  • Publication number: 20200086016
    Abstract: An apparatus and method are disclosed for providing a fluid communication path to a wound site through a drape. The apparatus comprises a body portion having a lower surface and an upper surface, at least one connection port, at least one suction port and at least one fluid communication passageway between the connection port and the suction port. A connector at an end of at least one tubular conduit is locatable through the drape into an orifice in the connection port to thereby provide a fluid communication path through the drape between the tubular conduit and the wound site.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: Neill Philip Bannister, Edward Yerbury Hartwell, Iain Michael Blackburn, Andrew Linton, Mark White, Tim Stern
  • Publication number: 20200086017
    Abstract: A resilient connector for a negative pressure wound therapy system. The connector includes a first lumen having an entrance dimensioned and configured for slidably engaging a projection of a canister adapter to provide fluid communication of the first lumen to a first portion of reduced pressure tubing and an exit dimensioned and configured for slidably engaging a first projection of a dressing adapter to provide fluid communication of the first lumen to a second portion of reduced pressure tubing. The connector further a second lumen having an entrance dimensioned and configured for slidably engaging a second projection of the canister adapter to provide fluid communication of the second lumen to a first portion of secondary pressure tubing and an exit dimensioned and configured for slidably engaging a second projection of the dressing adapter to provide fluid communication of the second lumen to a second portion of the secondary pressure tubing.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 19, 2020
    Applicant: DeRoyal Industries, Inc.
    Inventors: Vincent Denis Jardret, Scott Douglas Barnes, Walter Cleveland Cowart, Jonathan Matthew Cayce, Breanna J. Rhyne, Andrew Sullivan, Dhanvin S. Desai
  • Publication number: 20200086018
    Abstract: A negative pressure wound therapy device that includes a first tubing connectable in flow communication with a source of negative pressure configured for application of negative pressure to a wound site, a second tubing in flow communication with the wound site, and a valve.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 19, 2020
    Applicant: DeRoyal Industries Inc.
    Inventors: Vincent Denis Jardret, Jonathan Matthew Cayce, Walter Cleveland Cowart, Scott Dougles Barnes, Gregory S. Hodge
  • Publication number: 20200086019
    Abstract: A manual breast pump is disclosed. The manual breast pump comprises a breast cup configured to engage with a mother's breast and a reservoir at a base of the breast cup configured to collect milk extracted from the mother's breast. The reservoir is defined by a wall. The wall comprises a varying thickness from a top of the reservoir toward a bottom of the reservoir.
    Type: Application
    Filed: September 15, 2018
    Publication date: March 19, 2020
    Inventor: Poh Leng Jeffrey CHUA
  • Publication number: 20200086020
    Abstract: An expression kit (2) for use in a breast pump device (1) for extracting breast milk from a human breast comprises a breast pump body (20) having a first pressure chamber (21), a second pressure chamber (22), and a membrane portion (5) separating the first and the second pressure chamber (21, 22) from each other. The membrane portion (5) is configured to form a barrier between the first and the second pressure chamber (21, 22) for preventing leakage of human breast milk from the second pressure chamber (22) to the first pressure chamber (21), yet to allow for air exchange between the first and the second pressure chamber (21, 22), wherein the membrane portion (5) is hydrophobic and has the shape of a solid sheet being provided with holes (50) which are configured for rendering the sheet permeable to air and impermeable to liquid.
    Type: Application
    Filed: December 21, 2017
    Publication date: March 19, 2020
    Inventors: PAULUS CORNELIS DUINEVELD, JOHANNES PETRUS ANTONIUS MARIA VAN ASSELDONK
  • Publication number: 20200086021
    Abstract: The invention provides an introducer assembly for delivering a blood pump into vasculature of a subject, as well as a method for utilizing the assembly.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Applicant: NuPulseCV, Inc.
    Inventors: Valluvan JEEVANANDAM, Robert SMITH
  • Publication number: 20200086022
    Abstract: The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.
    Type: Application
    Filed: June 19, 2019
    Publication date: March 19, 2020
    Inventors: Ahmad El Katerji, Qing Tan, Christian Moyer, Alexander Ship, Sonya Sanat Bhavsar, Noam Josephy, Elazer R. Edelman, Brian Yale Chang, Steven Keller
  • Publication number: 20200086023
    Abstract: A method of starting an implantable blood pump including a first stator and a second stator, the method including detecting an electrical fault in one of a group consisting of the first stator and the second stator and commencing a startup of the first stator and the second stator in response to the electrical fault.
    Type: Application
    Filed: August 27, 2019
    Publication date: March 19, 2020
    Inventors: Carlos REYES, Justin WOLMAN, Mark Steven EGLER
  • Publication number: 20200086024
    Abstract: A microfluidic device for increasing convective clearance of particles from a fluid is provided. A network of first channels can be separated from a network of second channels by a first membrane. The network of first channels can also be separated from a network of third channels by a second membrane. Fluid containing an analyte can be introduced in the network of first channels. Infusate can be introduced into the network of second channels, and waste-collecting fluid can be introduced into the network of third channels. A pressure gradient can be applied in a direction perpendicular to the direction of fluid flow in the network of first channels, such that the analyte is transported from the network of first channels into the network of third channels through the second membrane.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 19, 2020
    Inventors: Christopher DiBiasio, Daniel I. Harjes, Joseph L. Charest, Jeffrey T. Borenstein
  • Publication number: 20200086025
    Abstract: A communication connection between a dialysis machine (such as a hemodialysis machine or a peritoneal dialysis machine) and a control device located away from the dialysis machine may be secured based on a safety protocol being implemented. The safety protocol may be executed in a server-side integrated circuit component and in a client-side integrated circuit component.
    Type: Application
    Filed: August 26, 2019
    Publication date: March 19, 2020
    Inventor: Stefan Konrad Marterstock
  • Publication number: 20200086026
    Abstract: Systems, methods, and/or apparatuses may be operative to perform a dialysis process using RBV-based UF control. Embodiments may include methods operative to receive RBV target information comprising population-based dialysis data of real patient outcomes of a patient population associated with the patient, determine an RBV value of a patient during the dialysis process, and determine UF information to control a UF pump of the dialysis device to maintain the RBV value within a target RBV range defined by the RBV target information. Other embodiments are described.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 19, 2020
    Inventors: Doris H. Fuertinger, Peter Kotanko, Sabrina Rogg
  • Publication number: 20200086027
    Abstract: Absolute blood volume in dialysis patients is a useful patient attribute to know for dialysis treatment, diagnosis, adjustments, etc. In some cases, it is difficult or impossible to directly determine absolute blood volume. Estimating absolute blood volume may be used to overcome the inability to directly determine the absolute blood volume. Estimating absolute blood volume may include obtaining a series of measurements of hemoconcentration of a patient over a time period, and estimating parameters for a physiological model based on the series of measurements. The absolute blood volume of the patient may be determined using the physiological model.
    Type: Application
    Filed: June 1, 2018
    Publication date: March 19, 2020
    Inventors: Yossi Chait, Joseph Horowitz, Christopher V. Hollot, Hamed Samandari, Michael J. Germain, Daniel Schneditz
  • Publication number: 20200086028
    Abstract: A medical fluid treatment system includes a source of purified water; at least one concentrate for mixing with the water from the source to form a treatment fluid; a disposable set including a pumping portion, a concentrate line in fluid communication with the concentrate source and the pumping portion, and a patient line in fluid communication with the pumping portion, the patient line including a filter having a membrane configured to filter the treatment fluid, the filter configured such that (i) fresh treatment fluid flowing from the pumping portion towards a patient flows through the membrane and (ii) used treatment fluid flowing through the filter from the patient to the pumping portion bypasses the membrane; and a medical fluid delivery machine including a pump actuator operable with the pumping portion of the disposable set.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 19, 2020
    Inventors: John Norman, Edward Szpara, Karl Cazzini
  • Publication number: 20200086029
    Abstract: A medical device, such as a hemodialysis machine or a peritoneal dialysis machine, is provided with control commands in a secure manner based on the commands being detected on a separate control component. The control commands are detected and thereupon a message is generated which contains a request to activate an operating element. Only if the indicated operating element has been activated is the control command forwarded to a dialysis machine for execution.
    Type: Application
    Filed: August 23, 2019
    Publication date: March 19, 2020
    Inventor: Stefan Konrad Marterstock
  • Publication number: 20200086030
    Abstract: A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include patient line state detector for detecting whether a patient line is primed before it is to be connected to the patient. The patient line state detector can also the ability to detect whether a patient line has been properly mounted for priming. Both patient line presence/absence and fill state can be determined using an optical system, e.g., one that employs a single optical sensor.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 19, 2020
    Applicant: DEKA Products Limited Partnership
    Inventors: Jacob W. Scarpaci, Simon C. Helmore, Eric J. VanWyk, Matthew J. Finch
  • Publication number: 20200086031
    Abstract: Provided is a blood purifying apparatus including a blood purifying filter in which mass transfer occurs between blood and dialysis fluid, a blood tube connecting the blood purifying filter and a patient to allow blood to flow therethrough, a dialysis fluid supply tube connected to the blood purifying filter and allowing dialysis fluid to be supplied to the blood purifying filter therethrough, a dialysis fluid discharge tube connected to the blood purifying filter and allowing dialysis fluid to be discharged from the blood purifying filter therethrough; and a fluid pumping device. The fluid pumping device further includes a plurality of chamber each having an internal space, a chamber pressurizing member disposed inside the plurality of chambers and compressing or expanding the chambers to thereby allow a fluid to flow therethrough, and a flow controller controlling a flow passage.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 19, 2020
    Inventor: Jake K. Lee
  • Publication number: 20200086032
    Abstract: The present invention concerns methods of treating a patient suffering from a traumatic brain injury (TBI), comprising contacting said patient's blood with a sorbent for an inflammatory mediator and kits for performing such treatments.
    Type: Application
    Filed: May 21, 2018
    Publication date: March 19, 2020
    Inventor: Phillip CHAN
  • Publication number: 20200086033
    Abstract: Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly-isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood.
    Type: Application
    Filed: October 9, 2019
    Publication date: March 19, 2020
    Inventors: Marc E. Voorhees, Christopher Park, Salvatore Privitera
  • Publication number: 20200086034
    Abstract: A control system is provided to restrict the flow rate of blood in a venous line 12 of a perfusion system 1 comprising a reservoir 10 supplied by the venous line 12 and supplying an outgoing line 22. The control system comprises an outgoing flow sensor 32 configured to determine an outgoing flow value indicative of the outgoing flow rate in the outgoing line 22, and a controller configured to process the outgoing flow value and to determine if the outgoing flow value exceeds a pre-set pairing threshold.
    Type: Application
    Filed: December 19, 2017
    Publication date: March 19, 2020
    Inventor: Stephen Turner
  • Publication number: 20200086035
    Abstract: Hemodialysis systems are described. A hemodialysis system may include a dialysate flow path through which dialysate is passed from a dialysate reservoir, which includes a valved vent to atmosphere, to an ultrafilter. The dialysate flow path includes a pneumatically actuated diaphragm-based dialysate pump for pumping fluid from the dialysate reservoir to the ultrafilter. The hemodialysis system may include a controller for controlling pneumatic actuation pressure delivered to the dialysate pump and at least one valve connecting the dialysate reservoir vent to the atmosphere. The hemodialysis system may be configured to actuate the dialysate pump and the at least one valve to introduce air into the dialysate flow path and expel liquid from the dialysate flow path to a drain.
    Type: Application
    Filed: October 21, 2019
    Publication date: March 19, 2020
    Applicant: DEKA Products Limited Partnership
    Inventors: MICHAEL J. WILT, Jason A. Demers, Kevin L. Grant, Brian D. Tracey, James D. Dale
  • Publication number: 20200086036
    Abstract: A non-surgical method of delivering a liquid radioactive solution from a source to a recipient comprising the steps of: determining a desired recipient level of radioactivity and recipient volume of the radioactive solution to be delivered to the recipient, providing a first valve having a waste position and a recipient position, providing a bolus conduit, a waste conduit and a recipient conduit, each conduit having a valve end being connected to said first valve, so that the first valve can establish a waste flow path in the waste position and a recipient flow path in the recipient position, the recipient flow path being different from said waste flow path, the bolus conduit comprising a measuring section and an internal volume, the internal volume being approximately equal to the desired recipient volume of the radioactive solution to be delivered to the recipient, arranging said first valve in the waste position, transporting a first amount of said radioactive solution through said waste flow path, the fir
    Type: Application
    Filed: December 21, 2017
    Publication date: March 19, 2020
    Inventors: Martin STENFELDT, Rune KRISTENSEN WIIK, Peter LARSEN
  • Publication number: 20200086037
    Abstract: An inline microgravity air trap device includes an elongate air trap chamber, the air trap chamber having a blind end, an opposite air outlet end containing a gas egress opening, a fluid inlet port connecting to a pressurized fluid supply, a fluid outlet port connecting the air trap chamber to a fluid delivery destination, a filter forming a tube having an interior, a first end at the blind end of the air trap chamber and a second end at the gas egress opening, and a structural insert in the interior of the tube, having a first insert end located at the blind end, and a second insert end located the air outlet end, where the chamber is formed to direct fluid from the pressurized fluid supply to accelerate centrifugally around the filter, forcing gas contained in the fluid to pass through the filter into the interior of the tube.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 19, 2020
    Inventors: Arthur Formanek, Mark Ottensmeyer, Tovy Kamine
  • Publication number: 20200086038
    Abstract: The present disclosure is directed to a cap to be worn by an individual having a scalp intravenous tube so as to help in maintaining the body temperature of the individual. The cap includes a body, at least one opening and a fastener. The body has a plurality of panels. The at least one opening is formed between the plurality of panels of the body. The fastener is positioned on a portion of at least one of the plurality of panels of the body to connect the plurality of panels of the body so as to attach the body of the cap to a head of an individual.
    Type: Application
    Filed: September 17, 2019
    Publication date: March 19, 2020
    Inventor: Joni Hawkins
  • Publication number: 20200086039
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Application
    Filed: November 18, 2019
    Publication date: March 19, 2020
    Applicant: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Publication number: 20200086040
    Abstract: An infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, where the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw.
    Type: Application
    Filed: March 25, 2019
    Publication date: March 19, 2020
    Inventors: Kevin L. Grant, Brian D. Tracey
  • Publication number: 20200086041
    Abstract: A pump module for an infusion pump includes a plunger-cylinder unit that can be coupled to the infusion pump in order to deliver fluid from a fluid feed line into a fluid drain line to a patient. The plunger-cylinder unit has a delivery chamber that is fluidically connected to the fluid feed line and the fluid drain line. The delivery chamber is delimited by the cylinder (14). The plunger can be moved linearly/back and forth in the axial direction. A plunger seal seals the plunger in relation to the cylinder. The section of the wall of the cylinder, over which the plunger seal passes during the back-and-forth motion of the plunger, is sealed in a sterile manner in relation to the surroundings.
    Type: Application
    Filed: May 23, 2018
    Publication date: March 19, 2020
    Inventors: JÜRGEN FUCHS, JÜRGEN HARTUNG, JÜRGEN STEGER
  • Publication number: 20200086042
    Abstract: A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Dean Kamen, John M. Kerwin, Gerald M. Guay, Larry B. Gray, Richard J. Lanigan, Stephen L. Fichera, Colin H. Murphy, Thomas F. Soldau, David Blumberg, JR.
  • Publication number: 20200086043
    Abstract: A device for infusing liquid medicaments such as insulin includes an infusion pump. The device can modify a medicament delivery protocol stored in memory to delivery an alternative medicament delivery protocol with the pump.
    Type: Application
    Filed: October 25, 2019
    Publication date: March 19, 2020
    Inventor: Sean Saint
  • Publication number: 20200086044
    Abstract: A disposable module that can be coupled to a reusable module in order to form a pump for dispensing a medicament substance to a user in a metered manner in a coupled state, comprising a housing that encases the following components: a reservoir for receiving the substance to be dispensed; and at least one extensible cannula, which is fluidically connected to the reservoir either after being inserted or in a permanent manner. The disposable module may also comprise an electrical energy store, wherein the electrical energy necessary for the reusable module can be obtained both from the disposable module and also from a rechargeable battery in the reusable module, in order to ensure redundancy of the energy necessary for the reusable module.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: Ursina Streit, Seline Staub, Thomas Buri, Patrick Hostettler, Juerg Steck, Christophe Hofer, Andreas Koehli, Florian Kuehni, Marc Labudde, Thomas Leuzinger
  • Publication number: 20200086045
    Abstract: An infusion pump apparatus includes a length of resilient tubing removably loadable in an infusion pump having a housing, a pumping mechanism, and a pump door. A latch member is pivotally mounted to the pump door and cooperates with a latch pin fixed on pump housing. A free-flow protection device is biased to pinch the tubing closed to stop fluid flow. The latch member has a first range of pivotal motion in a latching direction for causing the latch member to engage with the latch pin to secure the door in a closed position and a second range of pivotal motion in the latching direction for causing the latch member to actuate the free-flow protection device to unpinch the tubing and allow flow. The latch member pivots through at least a portion of the first range of pivotal motion before beginning to pivot through the second range of pivotal motion.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 19, 2020
    Inventors: Azur AZAPAGIC, Mohan Jonathan BARKLEY
  • Publication number: 20200086046
    Abstract: A reporting syringe, including a barrel in fluid communication with a needle connected with a first end of the barrel, a piston including a plunger, the piston positioned within a second end of the barrel and the plunger having a fluid-tight interaction with an interior of the barrel, and a microprocessor in electronic communication with a switch and a wireless module, the microprocessor configured to send an administration completion data from the wireless module after triggering the switch.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Jeremy Corbett, John Spencer, Nathaniel Mitchell
  • Publication number: 20200086047
    Abstract: A stimulation system for treating a patient comprises: a stimulator comprising at least one stimulation element for delivering stimulation to the patient, the delivered stimulation based on a set of stimulation settings; a controller for adjusting a stimulation setting of the stimulator; and a diagnostic device for measuring a physiologic response to the test stimulation on the patient. The set of stimulation settings comprise a set of test stimulation settings and a set of therapeutic stimulation settings. The stimulation comprises test stimulation delivered to the patient for a test duration, and therapeutic stimulation delivered to the patient for an extended duration. The test stimulation is based on the set of test stimulation settings and the therapeutic stimulation is based on the set of therapeutic stimulation settings. The set of therapeutic stimulation settings is based on an assessment of the measured physiologic response. Methods of delivering stimulation are also provided.
    Type: Application
    Filed: December 14, 2017
    Publication date: March 19, 2020
    Inventors: Andres Lozano, J. Christopher Flaherty
  • Publication number: 20200086048
    Abstract: Embodiments include methods and systems for maintaining glucose homeostasis. Systems can include a pump, a first reservoir including a homeostasis agent, an umbilical catheter capable of being advanced in the umbilical vein or in the falciform ligament, and a sensor. Systems can also include a biocompatible coating, a microprocessor in communication with the pump and the sensor, and a power supply. Methods can include implanting a pump and reservoir subcutaneously in a patient, advancing a catheter in the umbilical vein or in the falciform ligament, measuring a blood glucose level, pumping a homeostasis agent, and administering the homeostasis agent to the portal venous system.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 19, 2020
    Inventor: Amos Cahan
  • Publication number: 20200086049
    Abstract: The present in relates to a kit for treating or relieving incision site pain. According to the present invention, there is provided a kit for treating or relieving postoperative incision site pain, which makes effective treatment possible by injecting a pain relief drug or a treatment drug into a surgical site in situ after incisional surgery during an incisional surgical procedure, and stably and slowly releasing the drug.
    Type: Application
    Filed: April 3, 2018
    Publication date: March 19, 2020
    Inventors: IL KYU PARK, JUN HO KIM, JONG BAE CHOI, HUN UI KIM