Abstract: An actively-powered temperature data logger patch with wireless data communication includes a sealed, flexible battery configured to provide continuous electrical power, and a flexible circuit including a microprocessor, a temperature sensor configured to sense a temperature of a target subject, a wireless communication transmitter and an antenna. In one example, the temperature sensor is located at a first end of the patch, and the antenna is located at an opposite, second end of the patch. The patch is configured to conform to a curved surface of the target subject and includes an adhesive configured to be removably applied to skin of the patient. An external computing device is capable of receiving communication from the wireless communication transmitter of the patch via an electromagnetic field.

Abstract: A user-wearable sensor device may be configured to be directly or indirectly secured to a user or to an article worn by the user. The user-wearable sensor device may include at least one sensor configured to collect sensor data associated with an orientation of the user, a display unit including at least one LED or other visual indicator, a battery configured to provide power to at least the display unit, and a control system. The control system may be configured to determine the orientation of the user based on sensor data collected by the at least one sensor, maintain the display unit in a deactivated state in the absence of a defined activation input, detect a defined activation input, activate the deactivated display unit in response to detecting the defined activation input, and control the activated display unit based on the determined orientation of the user.

Abstract: An optical probe includes a lens combination, an optical fiber assembly, and a cover. The lens combination includes a first lens and a second lens. The first lens has a generally planar first lens surface defining an oval edge. The second lens has a generally planar second lens surface operatively coupled to the first lens surface. The second lens has four primary edges and at least two secondary edges connecting pairs of the primary edges. Each primary edge extends in substantially a straight line between two spaced-apart points at the oval edge of the first lens. The optical fiber and the lens combination are configured such that a light beam exiting the optical fiber enters the lens combination at an entering surface of the first lens, passes through the first lens and exits the first lens at the first lens surface. The cover circumferentially surrounds the optical fiber assembly.

Abstract: A system and method utilizing thermoacoustic imaging to estimating tissue temperature within a region of interest that includes an object of interest and a reference which are separated by at least one boundary located at least at two boundary locations. The system and method use a thermoacoustic imaging system that includes an adjustable radio frequency (RF) applicator configured to emit RF energy pulses into the tissue region of interest and heat tissue therein and an acoustic receiver configured to receive bipolar acoustic signals generated in response to heating of tissue in the region of interest; and one or more processors that are able to: process received bipolar acoustic generated in the region of interest in response to the RF energy pulses to determine a peak-to-peak amplitude thereof; and calculate a temperature at the at least two boundary locations using the peak-to-peak amplitudes of the bipolar acoustic signals and a distance between the boundary locations.

Abstract: A method of calibrating a PAI system (401-413) is described. The method includes a signal processing unit (404) determining optical fluence at voxels within arteries of a human or animal, and interpolating from these measurements to provide a fluence map with a fluence value for all voxels of interest. The system (404) stores the fluence map for subsequent use in making PAI measurements. The arterial optical fluence may be determined on the basis that the arterial oxygen saturation (SaO2) is the same throughout the arterial part of the circulation system.

Abstract: A magnetic resonance probe (2) includes a fiber optic sensor probe (32) and a sheath (38). The fiber optic sensor probe (32) includes a non-ferrous sensor (42) on a distal portion (36) configured for insertion into a subject, a locking element (34) connected to the distal portion (36), and a proximal portion (44) connected to the locking element (34) and in light communication via an optical fiber (48) with the non-ferrous sensor (42) and includes a connector (46). The sheath (38) covers the distal portion (36) of the fiber optic sensor probe (32), engages the locking element (34), and provides a sterile outer surface (70).

Abstract: An automated measurement device and method for coronary artery disease scoring is disclosed. An example device includes a stenosis determiner configured to receive a computerized model of a plurality of vascular segments of a patient, and analyze the model to determine locations of potential lesions. The example device further includes a vascular state score calculator configured to, for each potential lesion, determine a vascular state scoring tool (“VSST”) score based on at least one of a size of the potential lesion, a distance of the potential lesion from a branch point in the plurality of vascular segments, and a distance of the potential lesion to an adjacent potential lesion. The example device also includes a user interface configured to display the VSST scores for the potential lesions.

Abstract: A method and system for the analysis of a patient's oximetry data to detect sleep-disordered breathing is provided. The system employs an algorithm to reliably detect patient arousals and correlate those with accelerated heart rate and oxygen saturation levels in a manner that detects sleep-disordered breathing via the respiratory mask. Initially a timing channel is formed based on a plethsmography signal using an optical finger sensor. Based on the pleth waveform, a respiratory wave form is prepared that represents respiration rate. An arousal mask is applied to the signal based on attenuations in the pleth signal. Once arousals are identified the time required for changes to propagate from the lungs to the blood gas is subtracted from the onset time of the arousal. As a result if the timing agrees with dropping oxygen saturation or falling arterial pH then the arousal is indicated as a chemoreflex related arousal.

Abstract: A vital signs monitor for attachment to a human or animal thorax, the monitor having a low power mode and a high accuracy mode and comprising: a motion sensor configured to, in the low power mode, sample movement at a first frequency and, in the high accuracy mode, sample movement at a second frequency, the second frequency being greater than the first frequency; and a processor configured to, in the low power mode, process a series of the one or more movement samples captured by the motion sensor in the low power mode so as to form a measure of activity level, and to, in the high accuracy mode, cause a series of the movement samples captured by the motion sensor in the high accuracy mode to be stored at the vital signs monitor and/or transmitted by means of a transceiver; wherein the processor is configured to prevent the vital signs monitor entering the high accuracy mode from the low power mode when the activity level exceeds a first predefined or dynamic threshold.

Abstract: The heart rate monitor disclosed herein removes a step rate component from a measured heart rate by using one or more filtering techniques when the step rate is close to the heart rate. In general, a difference between the step rate and the heart rate is determined, and the step rate is filtered from the heart rate based on a function of the difference.

Abstract: An apparatus includes a strap configured to enable the apparatus to be worn by a user; an optical measurement element configured to be placed on a skin of the user, and to measure data related to heart activity of the user; communication circuitry configured to transmit the data related to heart activity of the user according to a Bluetooth standard on a 2.4 GHz band; and an antenna coupled with the communication circuitry, and configured to access a radio interface to transmit the data related to heart activity of the user.

Abstract: A method, a computer readable media and a hand-held device, the hand-held device may include a first sensor that is positioned such as to be contacted by a first hand of a user when the user holds the hand-held device; a second sensor that is positioned such as to be contacted by a second hand of the user when the user holds the hand-held device; wherein at least one sensor of the first sensor and the second sensor is a hybrid sensor that comprises an electrode, an illumination element and a light detector; and a health monitoring module arranged to process detections signals from the electrode and from the light detector such as to provide processed signals that are indicative of a state of the user.

Abstract: A guided meditation system, such as a virtual reality (VR) guided meditation system, provides biofeedback. Wearable devices (e.g., fitness trackers) record information about a physiological state of a user (e.g., heart rate, blood pressure, sleep, and activity data). Performing guided meditation exercises may help users improve their physiological state (e.g., by decreasing a user's heart rate). The VR guided meditation system automatically retrieves physiological state information from wearable devices or third party applications before and/or after a user performs guided meditation exercises. Based on the retrieved information, the VR guided meditation system provides biofeedback related to effects or potential correlations between an exercise and the user's physiological state. In particular, the biofeedback indicates a certain type of meditation, certain VR environment location, or certain meditation duration that is likely to improve the user's physiological state.

Abstract: A system for monitoring a subject for an arrhythmia includes an external monitoring device (EMD) configured to be disposed outside of a subject's body. The EMD includes a first communication component configured to receive, from a medical device, a first physiological parameter signal and an indication of a detected trigger event associated with a first portion of the first physiological parameter signal. The trigger event is indicative of a potential arrhythmia. The EMD also includes an analysis component configured to (1) identify a second portion of the first physiological parameter signal, where the second portion satisfies a discard criterion, (2) discard the second portion, and (3) perform an arrhythmia confirmation evaluation using a third portion of the first physiological parameter signal.

Abstract: A method of diagnosis is disclosed. The method comprises: acquiring an absolute component and a phase component of an input signal indicative of an impedance of an organ of a subject; determining baseline blood flow of the subject based on the phase component; determining transient changes in blood flow based on at least the absolute component; and displaying the baseline blood flow and the transient changes in blood flow.

Abstract: A method, an apparatus, and a kit including the apparatus and a fluorescence agent are provided for measuring a time-varying change in an amount of blood in a tissue volume, and include exciting a fluorescence agent in the blood, acquiring a time-varying light intensity signal during a pulsatile flow of the blood through the tissue volume, the pulsatile flow having a systolic and a diastolic phase resembling a conventional photoplethysmogram, and processing the acquired signal by applying a modified Beer-Lambert law to obtain a measurement of the time-varying change in the amount of blood in the tissue volume. The instantaneous molar concentration of the fluorescence agent is determined by utilizing a concentration-mediated change in a fluorescence emission spectrum of the fluorescence agent. There is further provided a fluorescence agent for use in the method.

Abstract: A measurement patch device may change length according to somatotype of a user, and may be joined with another measurement patch device integrally according to the need of different physiological lead measurement. Moreover, the two joined measurement patch devices may rotate with respect to each other, such that multi-channel or multi-lead physiological signal may be measured to save measurement time of physiological signal.

Abstract: An extended wear electrocardiography patch with wire interconnects is provided. The patch includes a flexible backing formed of an elongated strip of stretchable material with narrow longitudinal midsection evenly tapering inward from a distal end and a proximal end, the elongated strip adherable only at a contact surface defined on each of the ends; a pair of electrocardiographic electrodes interfaced to one or more of a set of electrode pads, each of the electrodes including an electrically conductive surface only exposed on the contact surface; a battery connected to one or more of the pads of the set via at least one flexile wire interconnect, the battery secured in place via a flexile wire; and the set of electrical contact pads included on the flexible backing and formed by a set of further flexile wires, the set configured to interface the electrodes and the battery with an electrocardiography monitor recorder.

Abstract: Cardiac mapping catheters and methods for using the catheters are described. The catheter can detect the presence, direction and/or source of a depolarization wave front associated with cardiac arrhythmia. A mapping catheter includes a plurality of bipolar electrode pairs in which the members of each pair are opposed to one another across a perimeter, for instance in a circular pattern. The spaced arrangement of the electrodes can be utilized to identify directional paths of moving electric fields or wave fronts in any direction passing across the endocardial surface. The catheters can be used to identify locations and types of triggers and/or drivers of cardiac arrhythmia including rotors, ectopic trigger foci and/or to delineate reentrant pathways.

Abstract: An ECG system measures and annotates a subdivision of the P wave of the ECG waveform from harmonic waveforms. Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients. Starting and ending discontinuity points are identified for a subdivision of the P wave of the ECG waveform and an APD is calculated for the subdivision. The ECG waveform is displayed along with a location of the P wave subdivision on the ECG waveform and the calculated APD.

Abstract: In order to estimate a movement command that a central nervous system is to select to implement a desired movement based on three feature amounts under the concepts of an antagonistic muscle ratio and an antagonistic muscle sum and based on a musculoskeletal model, a movement analysis apparatus includes: a myoelectric potential measurement unit to measure a myoelectric potential of a person who performs a movement; a movement measurement unit to measure a body movement; and a stiffness-ellipse calculation unit, an equilibrium-point calculation unit and a muscle synergy calculation unit to calculate, from measurement information obtained at the measurement units, feature amounts of a stiffness ellipse, an equilibrium point, and a muscle synergy that are base vectors describing the equilibrium point at an operating point based on a musculoskeletal model.

Abstract: Systems and methods are provided for detecting and analyzing changes in a body. A system includes an electric field generator, an external sensor device, a quadrature demodulator, and a controller. The electric field generator is configured to generate an electric field that associates with a body. The external sensor device sends information to the electric field generator and is configured to detect a physical change in the body in the electric field, where the physical change causes a frequency change of the electric field. The quadrature demodulator receives the electric field from the electric field generator and is configured to detect the frequency change of the electric field and to produce a detected response. The controller, coupled to the electric field generator, is configured to output a frequency control signal to the electric field generator and to modify the frequency of the electric field by adjusting the frequency control signal.

Abstract: A blood glucose tracking system and method measures emitted microwave energy transmitted to and accepted by blood vessels in a desired target area of a patient in order to determine, in real time and in vivo, appropriate blood glucose levels. A measurement unit comprises a transmitter operatively connected to an antenna to deliver energy towards appropriate subcutaneous blood vessels. The measurement unit determines an accepted energy power value in the blood vessels associated with the desired target area. This measurement energy power value is compared with a calibration value, and the difference is used to determine a resultant blood glucose value. The determined blood glucose value may further be acclimatized using additional sensed values compensating for biological and ambient factors relevant to the patient. The final determined blood glucose value can be displayed for reading and/or transmitted and stored for recording for further reference.

Abstract: In part, the disclosure relates to systems and methods of detecting struts in a blood vessel. In one embodiment, an intravascular data collection system and an intravascular data collection probe are used. An exemplary method may include one or more of the following steps converting an image of a blood vessel into an image mask, the image includes struts of a bioresorbable scaffold; inverting the image mask to create an inverted image mask, detecting an insular group of bright/signal containing pixels; and filtering the insular group of bright/signal containing pixels using one or more morphological filters to identify candidate struts; and validating the candidate struts to identify one or more struts of the bioresorbable scaffold.

Abstract: Detecting spatial location and rotation (pitch, roll and yaw) of an implantable programmable valve device having a direction of flow of fluid therethrough. A permanent-magnet rotor disk associated with the valve has magnets arranged in a ring. A single position within the ring represents a moveable reference marker position. Also included in the valve is a first fixed, stationary, non-moveable magnet disposed a predetermined distance relative to the moveable reference marker position. A magnetoresistive sensor array produces the asymmetric magnetic field pattern including a moveable reference marker corresponding to the moveable reference marker position in the ring and a first fixed reference marker corresponding to the first fixed, stationary, non-moveable magnet. An indicator device determines spatial location based only on the moveable reference marker and yaw based on the moveable reference marker relative to the first fixed reference marker.

Abstract: Guidewires and methods useable in conjunction with image guidance systems to facilitate performance of diagnostic or therapeutic tasks at locations within the bodies of human or animal subjects.

Abstract: A method of diagnosis. The method can include the steps of sampling the breathing of a patient and from the sampling, obtaining a waveform corresponding to a pattern of the breathing of the patient in which the waveform is a repetitive waveform that is indicative of a carbon dioxide concentration in air expired by the patient. The method can also include the steps of processing the waveform to obtain a set of data that reflects the carbon dioxide concentration in the expired air and based on the processing of the waveform, detecting a potential adverse respiratory event in the patient.

Abstract: A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.

Abstract: According to an aspect, a testing instrument that is used for testing an airway protection function includes: a pipe portion continuous from an inlet port to an outlet port, the pipe portion having a plurality of holes penetrating the pipe portion from an outer surface of the pipe portion to an inner surface of the pipe portion, the holes being provided for guiding a reagent gas mixture to the inside of the pipe portion; and a guide portion covering all of the holes to form a closed space and guiding the reagent gas mixture to the closed space from an inflow port.

Abstract: The present invention provides a method for predicting seizures and for detecting seizures, and other potentially injurious or life-threatening events, optionally in conjunction with a mobile device. In an embodiment, a portable device provides epilepsy seizure prediction, detection, monitoring, analysis and alerting for epilepsy patients or other people afflicted with seizures. In an embodiment, the portable device may alert and communicate information to health care providers, caregivers and family members, emergency services, and the like. Collected data may be reviewed and analyzed for use in developing specific criteria for predicting and detecting seizures and other potentially injurious or life-threatening events.

Abstract: A method and an apparatus for performing the method are disclosed. The method includes obtaining cardiac output power data on a user; obtaining kinetic data characterizing physical exercise intensity of the physical exercise performed by the user; detecting that a measured cardiac output power exceeds a first threshold or that physical exercise intensity changes according to a rate exceeding a second threshold; upon the detecting, determining a synthetic cardiac output power parameter based at least partly on the kinetic data; and outputting the synthetic cardiac output power parameter.

Abstract: The present invention relates to a powder composition, in particular a fingerprint powder composition for the visualisation of latent fingerprints. Such fingerprint powder compositions comprise carbogenic nanoparticles which, when mixed with a suitable diluent (including any existing or future fingerprint powders), exhibits excitation-dependent emission properties which enable the fingerprint powder compositions and imagable fingerprint impression patterns formed thereform to be imaged in a variety of different colours by simply varying the wavelength(s) of any excitation radiation. As certain backgrounds can render visualisation of fingerprint impression patterns very difficult, having the flexibility to judiciously tune the foreground colour of the fingerprint impression patterns is a significant advantage since it permits instantaneous improvements in visualisation without needing to resort to using a different fingerprint powder.

Abstract: A method for non-invasive glucose monitoring includes the following steps. At least one ray of light is emitted from at least one light source. The light emitted from the light source is leaded into an eyeball and focused on the eyeball through a first beam splitter. The reflected light reflected from the eyeball is transmitted through the first beam splitter to a set of photo detectors. Optical angular information and energy information of the reflected light transmitted to the set of photo detectors are measured. Optical angular difference and energy difference resulting from the light emitted from the light source and the reflected light transmitted to the set of photo detectors are obtained. Glucose information is obtained by analyzing the optical angular difference and the energy difference. Since glucose information has a corresponding relationship with blood glucose information, blood glucose information may be obtained.

Abstract: A breast measurement apparatus includes a distance measurement unit measuring a distance from a skin to a light absorption portion for a measurement region of a breast which is a normal region including no tumor or an object region including a tumor, a light measurement unit measuring a hemoglobin amount in the measurement region by a light measurement method using measurement light of a predetermined wavelength, a correlation data storage unit storing normal correlation data of the distance to the light absorption portion and a normal hemoglobin amount generated based on measurement results for normal regions, and an evaluation value calculation unit calculating a property evaluation value of the tumor based on the normal hemoglobin amount, obtained from the normal correlation data and the distance to the light absorption portion in the object region, and an object hemoglobin amount in the object region.

Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Abstract: At least one microneedle comprises a hydrogel material that includes a substance that fluoresces when the substance interacts with an analyte. A magnitude of the fluorescence varies as a function of the concentration of the analyte. During use, the hydrogel material is illuminated with illumination light in a first wavelength range while the hydrogel material interfaces with the dermal interstitial fluid layer of a subject, and a photosensor generates an output that corresponds to an amount of light received in a second wavelength range.

Abstract: A system for transdermal alcohol sensing to be worn near a skin surface of a user, including: an alcohol sensor; a microporous membrane; a housing coupled to the alcohol sensor and the membrane, defining a volume between the alcohol sensor and a first membrane side, and fluidly isolating the volume from a second membrane side opposing the first membrane side; an electronics subsystem electrically coupled to the alcohol sensor, operable to power and receive signals from the alcohol sensor; and a fastener operable to position the second membrane side proximal the skin surface.

Abstract: Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

Abstract: A biosensor having a hollow coil having wires coiled in parallel and an electronic circuit component operably connected to the coil, wherein the wires include at least a first coiled wire which may be used as a counter electrode, a second coiled wire which may be used as a working electrode and a third coiled wire which may be used as a reference electrode, wherein the second coiled wire is provided with a biocompatible layer having a bioreceptor, wherein the electronic circuit component is capable of generating an input signal for a transceiver based upon the activity of the bioreceptor and wirelessly sending the input signal to the transceiver, wherein the electronic circuit component is encapsulated in a biocompatible resin.

Abstract: A lancet needle with an alignment and engagement notch, with material of the lancet body extending into the notch to more securely retain the needle to the lancet body, whereby a shorter needle can be utilized than with typical lancets. The notch optionally also provides a registration point for rotational and/or axial alignment of the needle during overmolding to form the lancet body, for example to maintain consistent positioning of the needle's beveled point.

Abstract: Methods and apparatus for blood sampling from skin capillaries are provided. Blood extraction is improved by applying gradient pressure in a proximal to distal direction of an extremity. Blood is extracted and sampled from the skin capillaries with a blood sampling mechanism of at least a lancet and testing kit.

Abstract: Methods are provided for non-invasive early screening of a subject for a neurodegenerative disorder, by analyzing one or more parameters associated with the neurodegenerative disorder.

Abstract: A living body state estimation apparatus acquires information indicating a state of a living body. The living body state estimation apparatus is configured to include an electrocardiogram signal acquisition unit which acquires an electrocardiogram signal of the living body and an information acquisition unit which acquires a parameter as the information, the parameter specifying a predetermined function indicating a probability distribution for a reference wave interval which is a time interval between peaks of consecutive predetermined reference waves in the acquired electrocardiogram signal.

Abstract: A method of analysing at least one hair surface using a 3D printer includes collecting a first imaging data for the at least one hair surface; applying at least one treatment to the at least one hair surface, the at least one treatment including at least one benefit agent; collecting a second imaging data for the at least one hair surface after applying the at least one treatment; converting the first imaging data into a first formatted data, the first formatted data associated with the 3D printer; converting the second imaging data into a second formatted data, the second formatted data associated with the 3D printer; producing a first 3D model of the at least one hair surface from the 3D printer using the first formatted data; and producing a second 3D model of the at least one hair surface from the 3D printer using the second formatted data.

Abstract: Axial stress or similar properties in a stressed tendon or ligament are measured by mechanical excitation of a shear wave in the tendon or ligament measured using ultrasonic displacement techniques at least two different longitudinal positions to derive a shear wave propagation speed. This shear wave propagation speed may be equated to an axial stress on the tissue using a model. Rapidly repeated measurements allow dynamic axial stress measurements to be obtained for clinical study.

Abstract: This document discusses, among other things, systems and methods for managing pain of a subject. A system may include a sensor circuit configured to sense a respiration signal and a heart rate signal. A pain analyzer circuit may determine respiratory cycles and respiratory phases in a respiratory cycle, and generate one or more signal metrics indicative of respiration-mediated heart rate variation. The pain analyzer may generate a pain score using the signal metrics indicative of respiration-mediated heart rate variation. The pain score may be output to a user or a process. The system may include an electrostimulator to generate and deliver closed-loop pain therapy according to the pain score.

Abstract: This document discusses, among other things, systems and methods for managing pain of a subject. A system may include a motion sensor configured to sense at least one functional signal indicative a physical state of the subject. The at least one functional signal may include at least one motor activity signal or at least one sleep state signal. A pain analyzer circuit may extract, from the functional signal, signal metrics indicative of subject motor control or kinetics, and generate a pain score using the signal metrics. The pain score may be output to a user or a process. The system may additionally include an electrostimulator to generate and deliver a closed-loop pain therapy according to the pain score.

Abstract: A method for patient setup includes: obtaining a first two-dimensional movie having a first plurality of image frames; obtaining a first plurality of two-dimensional images; and displaying the first plurality of two-dimensional images together with the image frames from the first two-dimensional movie in an overlay configuration and in a synchronized manner, wherein the act of displaying is performed during a patient setup procedure. A method for patient setup includes: obtaining a plurality of three-dimensional images; obtaining a first two-dimensional movie having a first plurality of image frames; determining a first plurality of two-dimensional images from the plurality of three-dimensional images; and displaying the first plurality of two-dimensional images together with the image frames from the first two-dimensional movie in an overlay configuration and in a synchronized manner, wherein the act of displaying is performed during a patient setup procedure.

Abstract: A method for titrating a stimulation parameter for one or more electrode contacts in a system for stimulating a hypoglossal nerve of a patient includes activating one of the one or more electrode contacts to stimulate the hypoglossal nerve of the patient, obtaining a first and/or second physiological measurement from the patient, comparing the first and/or second physiological measurement to a first and/or second predetermined target value, adjusting a stimulation parameter for the one of the one or more electrode contacts if the first and/or second physiological measurement differs from the first and/or second predetermined target value.

Abstract: Disclosed herein is a non-invasive system for determining tissue composition. The system comprises an imaging system with a non-invasive probe, a signal analyzer, and a correlation processor. The probe includes active imaging components for emitting energy and collecting imaging data including reflected signals from an object of interest. The signal analyzer analyzes the imaging data and determines one or more signal properties from the reflected signals. The correlation processor then associates the one or more signal properties to pre-determined tissue signal properties of different tissue components through a pattern recognition technique wherein the pre-determined tissue signal properties are embodied in a database, and identifies a tissue component of the object based on the pattern recognition technique.