Abstract: A medical device is configured to produce a cardiac motion signal by sampling a signal produced by an axis of a motion sensor, starting a blanking period, suspending the sampling of the signal during at least a portion of the blanking period, and restarting the sampling of the signal at the sampling frequency before the blanking period has expired. The medical device may detect a cardiac event from the cardiac motion signal and generate a pacing pulse in response to detecting the cardiac event in some examples.

Abstract: Methods for determining stimulation for a patient having a stimulator device are disclosed. A model is received at an external system indicative of a range or volume of preferred stimulation parameters, which model is preferably specific to and determined for the patient. The external system receives a plurality of pieces of fitting information for the patient, including information indicative of a symptom of the patient, information indicative of stimulation provided by the stimulator device during a fitting procedure, and/or phenotype information for the patient. The external system determines one or more sets of stimulation parameters for the patient using the pieces of fitting information. In one example, training data is applied to the pieces of fitting information to select the one or more sets of stimulation parameters from the range or volume of preferred stimulation parameters in the model.

Abstract: A heart pacemaker according to the present invention includes a generator configured to generate nonlinear electrical energy using a friction element and an energy harvester configured to sequentially store the generated nonlinear electrical energy in multi-stage multiple energy storages and supply the electrical energy stored in the multiple energy storages.

Abstract: A feedthrough for a cochlear implant or other medical device can include contacts disposed on an outer perimeter thereof. By disposing the contacts on the perimeter, the number of contacts on the feedthrough can be increased, the size of the feedthrough reduced, or both.

Abstract: Methods and systems for providing stimulation therapy are disclosed. Embodiments of the system include an implantable stimulator and an external controller configured to control the implantable stimulator. A clinician can prescribe a set amount of stimulation therapy to a patient. The external controller is programmed with the prescription. As the patient uses the external controller and the stimulator device the external controller tracks the amount of stimulation the patient uses. Once the patient has used all of the prescribed therapy the patient may return to the clinician for a follow-up appointment.

Abstract: Systems and methods are provided for managing patient activated capture of transient data by an implantable medical device (IMD). The systems and methods collect transient data using the IMD. The collected transient data is stored in a temporary memory section of the IMD. The IMD receives a patient activated storage request including activation information related to a patient designated trigger point from an external device. The IMD transfers a segment of the transient data from the temporary memory section to a long-term memory, wherein the segment of transferred transient data is based on the trigger point. The activation information includes an elapsed time corresponding to a duration of time between entry of the trigger point and issuance of the patient activated storage request by an external activation device.

Abstract: An implantable cardiac defibrillator (ICD) system includes an ICD implanted subcutaneously in a patient, a defibrillation lead having a proximal portion coupled to the ICD and a distal portion having a defibrillation electrode configured to deliver a defibrillation or cardioversion shock to a heart of the patient, and a pacing lead that includes a distal portion having one or more electrodes and a proximal portion coupled to the ICD. The distal portion of the pacing lead is implanted at least partially along a posterior side of a sternum of the patient within the anterior mediastinum. The ICD is configured to provide pacing pulses to the heart of the patient via the pacing lead and provide defibrillation shocks to the patient via the defibrillation lead. As such, the implantable cardiac system provides pacing from the substernal space for an extravascular ICD system.

Abstract: A subcutaneously implantable device includes a clip that is configured to anchor the subcutaneously implantable device to a muscle, a bone, and/or a first tissue, and a first prong with a proximal end attached to the clip and a distal end extending away from the clip that is configured to contact an organ, a nerve, and/or a second tissue. A first electrode on the first prong is configured to contact the organ, the nerve, and/or the second tissue. A wire conductively connected to the first electrode is configured to be connected to an external device that is positioned outside of a patient's body to electrically connect the subcutaneously implantable device to the external device.

Abstract: A system and method for enhancing sensory function of an individual are disclosed. The system comprises a generalized brain-skin interface (GBSI), configured to enable the individual to experience senses. The system further comprises a sensor, a processor, and an epidermal neuro-oscillating patch (ENOP). The sensor is configured to receive environmental data surrounding the individual. The processor in communication with the sensor is configured to receive environmental data from the sensor and convert it into an analog vibration pattern. The epidermal neuro-oscillating patch (ENOP) is removably fastened to the skin of the individual, configured to produce a sequence of vibrations based on the analog vibration pattern received from the processor and directly transmit it to the skin for stimulating the nerves of the individual, thereby effectively training the brain of the individual to learn and equate the sequence of vibrations for experiencing senses of the physical environment of the individual.

Abstract: Methods are provided for targeting cancer cells that over-express voltage-gated sodium channels (VGSCs or “sodium channels”) and causing osmotic lysis of these cancer cells by initially inhibiting the sodium, potassium-adenosine triphosphatase (Na+, K+-ATPase or “sodium pump”), and then stimulating the VGSCs by pulsed magnetic field gradients to cause sodium and water to enter the cancer cells.

Abstract: A medical device assembly is provided for removable insertion into a catheter with a lumen. The medical device assembly comprises an electromagnetic radiation (EMR) source for providing non-ultraviolet, therapeutic EMR having an intensity sufficient to inactivate one or more infectious agents and/or to stimulate healthy cell growth causing a healing effect, and a removable EMR conduction system at least partially insertable into and removable from the lumen of the catheter. The EMR conduction system has at least one optical element providing axial propagation of the therapeutic EMR through an insertable elongate body. The elongate body may have an exterior surface between a coupling end and a distal end tip that has at least one modified portion permitting the radial emission of therapeutic EMR from the elongate body proximate the modified portion. Such modified portion may be gradient along the exterior surface.

Abstract: A system for treatment of wounds consists of a treatment housing, a fluid delivery mechanism for supplying debridement fluids to the wound treatment area, an evacuation mechanism for evacuation of debris from the treatment chamber, handheld device is connected to the treatment housing, wherein its interior accommodates a laser source, a scanning device, an image recording device and at least one sensors/detectors, a control unit having a microprocessor for controlling operation of the system. The sensors detect concentration of various substances in the wound, and microprocessor analyzes data obtained by the sensors and generates signals to adjust parameters of the laser, the liquid dispensing nozzles and the suction outlet to optimize removal of necrotic tissue so as to ultimately to promote wound healing.

Abstract: Methods and systems for use in treating one or more patient's sensory impairment, e.g., associated with peripheral neuropathy. An exemplary system may be configured to generate treatment information for treating sensory impairment in at least one body portion using photonic energy from a therapeutic laser based on data indicative of damage.

Abstract: A system to be used to treat Leukemia, comprises a device to power, control and monitor an ultraviolet radiation as well as to monitor a blood contactless conductivity; and a catheter assembly with an inner dialysis catheter, an ultraviolet radiation source and a differential coil sensor. The system is using wavelengths of ultraviolet radiation to destroy infectious microbes that are in the blood and that are inside circulating tumor cells directly and indirectly as well as to destroy infectious microbes at primary tumor location (bone marrow). This is done without withdrawing the blood out of the body. Furthermore, the system measures a blood conductivity to evaluate the treatment process in a real time during the operation.

Abstract: It is provided a method for determining a distribution of spots for use with ion beam therapy for providing the spots in a target volume, wherein each spot represents a collection of ions of a specific energy level and of a specific size at a specific lateral location. The method is performed in a treatment planning system and comprises the steps of: dividing the target volume in a plurality of target sections based on a user configuration comprising at least one spot size strategy defining a maximum spot size at the location of a Bragg peak; assigning a spot size strategy to each one of the target sections based on the location of the respective target section; and determining, within each target section, spots in accordance with its spot size strategy.

Abstract: Solutions are provided herein that specifically accounts for biological effects of tissue during radiation planning (such as treatment planning). In one or more embodiments, the biological effects may be calculated by accessing a knowledge base to determine reference data comprising at least one biological characteristic corresponding to the at least one organ, predicting a biological effect for the plurality of identified structures based on the biological characteristic corresponding to the at least one organ, and generating or modifying a radiation plan based on the biological effect. By incorporating biological data and fraction dose information, dose-estimation models can be created and trained to more accurately estimate dose absorption and effectiveness. Moreover, existing estimation models may be adapted to create dose estimations that account for the biological efficiency of target structures.

Abstract: The present disclosure relates to a system and a method. The system may include a magnetic resonance imaging (MRI) apparatus configured to acquire MRI data with respect to a region of interest (ROI) and a therapeutic apparatus configured to apply therapeutic radiation to at least one portion of the ROI. The MRI apparatus may include a plurality of main magnetic coils arranged coaxially along an axis, a plurality of shielding magnetic coils arranged coaxially along the axis, and a cryostat in which the plurality of main magnetic coils and the plurality of shielding magnetic coils are arranged.

Abstract: A method for measuring radiotherapy doses on a subject undergoing radiotherapy or other treatments with ionizing radiations includes: electrically insulating the subject during the radiotherapy treatment; applying at least one electrode to the subject, or connected to an amplifier with a system for acquiring the signal outgoing from the amplifier; detecting, by means of the at least one electrode, the voltage pulse produced during the radiotherapy treatment and deriving from the ionization secondary electrons set into motion and/or by the loaded net charge induced in the subject; converting said voltage pulse into a value of charge induced by the treatment in the subject; and determining the dose of ionizing radiations received by the subject by a processing system which uses the above value of the induced charge, the energy spectrum of the incident beam and the contact surface of the incident beam on the subject.

Abstract: A neutron capture therapy system, including a beam shaping assembly, and a vacuum tube and at least one cooling device. The beam shaping assembly includes a beam inlet, an accommodating cavity accommodating the vacuum tube, a moderator adjacent to an end portion of the accommodation cavity, a reflector surrounding the moderator, and a radiation shield and a beam outlet arranged in the beam shaping assembly. An end portion of the vacuum tube is provided with a target. The cooling device undergoes a nuclear reaction with a charged particle beam incident from the beam inlet to produce neutrons. The moderator decelerates the neutrons produced by the target to an epithermal neutron energy region. The reflector leads deviating neutrons back to the moderator. At least one accommodating pipeline accommodating the cooling device is arranged in the beam shaping assembly. A filler is filled between the cooling device and the accommodating pipeline.

Abstract: Techniques for selective modulation of motor neuronal activity in a peripheral nervous system using a focused ultrasound assembly are provided. Methods include adjusting a pulse repetition frequency parameter of a focused ultrasound to selectively modulate a location on a peripheral nerve and modulating the peripheral nerve with the focused ultrasound to increase a temperature of the peripheral nerve. The modulating can comprise one or more of exciting and inhibiting the peripheral nerve with the focused ultrasound, either separately or in combination. Methods can further include locating the peripheral nerve using an imaging probe, monitoring a physiological response to the modulating, and changing the one or more ultrasound parameters in response to the physiological response. Systems for use in the modulation of peripheral nerves are also provided.

Abstract: This invention relates to skincare compositions, in particular compositions effective in the treatment of acne vulgaris, and to methods of treatment of the skin that involve the application of such compositions, wherein the compositions comprise salicylic acid or a salt thereof in combination with at least two actives selected from the group consisting of lactic acid or a salt thereof; glycyrrhizinic acid or a salt or a derivative thereof; bisabolol; cetylhydroxyproline palmitamide; allantoin; niacinamide; and Epilobium angustifolium extract.

Abstract: A device for supplying breathing gas to a user includes: a mask having a breathing opening; and a bag having a bag opening that is connected to the breathing opening in fluid communication, wherein the device further includes an adjustable exhalation valve, wherein the adjustable exhalation valve is in fluid communication with the bag. Thus, the device for supplying breathing gas to a user provides protection against hyperventilation, toxic gases and smoke.

Abstract: A retrofittable mount system for a mask having a mask window comprises a sensor removably mounted to the mask to collect information about an environment as sensor data, wherein the sensor is removably mounted to the mask with a first mount mechanism that does not penetrate the mask window. A processor is coupled to the sensor, wherein the processor executes one or more cognitive enhancement engines to process the sensor data into enhanced characterization data. An output device is removably mounted to the mask with a second mount mechanism without penetrating the mask window. The output device receives the enhanced characterization data from the processor and communicates the enhanced characterization data to a mask wearer, such that the enhanced characterization data is integrated into natural senses of the wearer and optimized for the performance of a specific task of the wearer to reduce the cognitive load of the wearer.

Abstract: There is disclosed a harness for breathing apparatus comprising a structural support member for supporting a vessel of breathable gas, a waist belt, and a pivot joint mechanism coupling the structural support member to the waist belt. The pivot joint mechanism comprises a release part which is movable to decouple the structural support member from the waist belt.

Abstract: The present system for fall restraint includes a mounting frame connected to a trigger mechanism and firing blocks, with a trigger cable extending through apertures in the mounting frame and trigger mechanism. Sudden movement by a user, such as a fall, actuates the trigger mechanism to trigger the firing blocks. The firing blocks are loaded with anchors and firing cartridges. Triggering the firing blocks causes the cartridges to fire, propelling the anchors into an anchoring surface, such as a roof. Because the user is connected to the trigger cable, once the anchors deploy the user is anchored to the roof and their fall arrested.

Abstract: Embodiments relate generally to systems and methods for quickly detecting a fall and alerting appropriate parties of the fall. A fall protection device may comprise a fall detection module operable to sense when a fall occurs and generate wireless beacon, where the beacon may be received (or picked up) by any number of wireless devices, including wireless gateways, monitoring stations, and mobile devices.

Abstract: A system for storing a hazardous product including a housing unit defining a product opening and a product door coupled to the housing unit adjacent to the product opening, wherein the product door is configured to form a seal with the housing unit about the product opening in response to a thermal event.

Abstract: A Fire Protection System for Runaway Grass and Forest Fires and Method for Use for protecting residential, commercial and governmental structures made of a heat reflective cover configured to fully encase the structure, a fire proof spray foam—approximately 2 to 12 inches, with fire retardant additive, multiple hold down straps, a series of anchors, a pre spray release coating a set of corner bands whereby the system, broadly considered, can be individually installed into a position to completely isolate a free standing structure from an external fire and can be readily customized to fit varying size structures which can prevent damage to a free standing structure and its contents from an external wild fire or firestorm.

Abstract: A fire suppressing device including a torus container with a main body defining an interior chamber and a discharge port, the interior chamber configured to receive and retain metal organic framework materials. The fire suppressing device also includes an inductor coil extending through the interior chamber of the torus container and surrounding the metal organic framework materials. The inductor coil is configured to heat the metal organic framework materials to form a fire suppressing substance that is conveyed through the discharge port.

Abstract: A ventilation closure system includes a damper, a shape memory alloy actuator, and a heating device. The shape memory alloy actuator is coupled to the damper. The shape memory alloy actuator has a first state in which the damper is positioned to permit airflow in the duct and has a second state in which the damper is positioned to obstruct the airflow in the duct. The shape memory alloy actuator is configured to change from the first state to the second state responsive to the shape memory alloy actuator attaining a first temperature responsive to heat released by an exothermic reaction in a compartment associated with the duct. The heating device is configured to heat the shape memory alloy actuator to maintain the damper in a position that obstructs the airflow in the duct.

Abstract: A containment system for a hazardous product includes a housing unit for storing the hazardous product. The housing unit includes sensors disposed throughout for detecting a thermal event. The system further includes an active fire suppression system configured to suppress the thermal event based on thermal event information received from the sensors. The system also includes a controller for processing signals from the sensors and activating the active fire suppression system, such as providing fire suppressants locally and/or globally or active venting. The system further includes a passive fire suppression system configured to suppress the thermal event using passive suppression without requiring activation from the controller, such as by coating surfaces of the system or using temperature sensitive venting or suppressant provision. The system may further include a training system to mimic the thermal event.

Abstract: A system for storing a hazardous product including a housing unit having an interior volume and a door coupled to the housing unit configured to provide access to the interior volume. The system includes an electrical connection configured to transmit electricity into or out of the interior volume. The system further includes a ventilation system for directing gasses and heat produced during a thermal event out of the interior volume.

Abstract: The invention relates to fire-fighting ground vehicles. A mobile fire extinguishing apparatus with pressurized foam generation comprises: a mixing chamber for supplying foam to a fire; and, a water supply system comprising a water supply pump with a drive, a foam-forming concentrate supply system comprising a foam pump with a drive, and also an air supply system comprising an air compressor with a drive. The drives of the compressor and of the foam pump are in the form of an adjustable hydraulic transmission of the air compressor drive and an adjustable hydraulic transmission of the foam pump drive, which are connected to a driving motor. The apparatus comprises a water meter, a gate valve having an electric drive, and a non-return valve, which are mounted on a water supply pipe between the water supply pump and the mixing chamber, and an electronic control unit for the gate valve.

Abstract: Automatic fluid control assemblies and methods for fire protection include an arrangement of electrically operated control points, a valve body and a controller to operate the fluid control assembly. The automatic fluid control assembly has an inlet, an outlet and a valve body to control flow between the inlet and the outlet. An electric latch includes a first electrically operated control point and a second electrically operated control point in fluid communication with a control line to control the flow of fluid control include controlling a plurality of electrically operated control points to perform any one of: a leak test, a trip test, a flow test, a water delivery test, and a validation test of a non-trip condition and a trip condition.

Abstract: Provided are embodiments including a method, device and system for an interconnected fire detection and extinguishing system that is implemented in an integrated manner The embodiments include a detector for detecting a condition associated with at least one of a fire or smoke, and an extinguisher operably coupled to the detector, wherein the extinguisher includes an extinguishing agent.

Abstract: The invention concerns a method of checking the implementation of maintenance works in a fire extinguishing installation, wherein there is provided an identification (3) which contains a radio identification means, for example a transponder chip or an NFC tag which is fixedly connected to a unit (2) to be maintained so that the identification (3) cannot be non-destructively removed from the unit to be maintained, wherein the identification (3) contains data of the unit (2) to be maintained and wherein the unit to be maintained is part of the fire extinguishing installation and has to be uninstalled for maintenance, wherein there is provided a reading unit (8) with which the identification of the unit (2) to be maintained and the data thereof are read and wherein the identification (3) is arranged concealed or shielded on the unit (2) to be maintained in such a way that the data of the identification cannot be read with the reading unit (8) when the unit (2) to be maintained is in the non-uninstalled state.

Abstract: Disclosed are fire extinguishants comprising from about 20% to about 80% by weight of 1-chloro-3,3,3-trifluoropropene (HFO-1233zd) and from about 20% to about 80% by weight of 1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)-3-pentanone (FK5-1-12), and to methods, systems and containers which use the fire extinguishants.

Abstract: A fire extinguishing composition includes a propellant, a dry chemical fire extinguishing agent and an anti-decomposition agent.

Abstract: A compact and portable exercise device, that can comprise a base frame portion, a first lower support member coupled with a first side of the base frame portion and extending upward from the first side of the base frame portion, a second lower support member coupled with a second side of the base frame portion and extending upward from the second side of the base frame portion, a first upper support member coupled with the first lower support member, and a second upper support member coupled with the second lower support member. Some embodiments of the device can also have a first handle member extending away from a front surface of the first lower support member, a second handle member extending away from a front surface of the second lower support member, and/or a bar extending at least between the first upper support member and the second upper support member.

Abstract: An adjustable resistance system for use with an indoor cycle comprising a magnetic resistance assembly, a friction brake assembly, and a resistance adjustment assembly.

Abstract: An aquatic exercise system includes a pool and an aquatic exercise apparatus positioned in the pool. The aquatic exercise apparatus includes a base and an aquatic exercise pole having a first substantially straight section, a second substantially straight section, and a curved transition section between the first substantially straight section and the second substantially straight section. The curved transition section includes a bend, and the aquatic exercise apparatus is positioned in the pool such that bend is above a surface of water in the pool.

Abstract: The present invention relates to a system for generating a force, in particular a driving force comprising: a first unit comprising a first tubular element, first magnetic means, a second unit comprising a second tubular element, where said second tubular element is coaxial with said first tubular element, second magnetic means, third magnetic means. Said first magnetic means are arranged within said first tubular element, and said second magnetic means and said third magnetic means are arranged on said second tubular element so as to be opposed to each other. Said first tubular element is arranged within said second tubular element and is configured to rotate of a predetermined rotation angle in such a way that, when said first tubular element rotates, said first magnetic means rotates with respect to said second magnetic means and said third magnetic means, so that a predetermined first force is generated by said system.

Abstract: An exercise bag apparatus, comprising: a cover comprising a re-sealable opening; and, an inner sleeve disposed within the cover, when the exercise bag apparatus is fully assembled, comprising a re-sealable opening and an inner cavity configured for holding a weighty substance therein.

Abstract: A deadlift device includes a cylindrical shaft attached to a base with a selectable weight. Horizontal channels in the shaft have a main horizontal through hole with a downwardly extending keyhole slot extension with beveled edges, so that portions of one or more resistance bands may be routed through the keyhole slots and used with minimal wear. A removable dual handle with right and left hand grip portions may be attached at any of the channels. An alternative removable short horizontal bar may be inserted at at any of the channels to permit kettlebell swing exercises. The device may be used effectively with a range of lift and walking exercises using the deadlift device with added weights and/or one or more resistance bands.

Abstract: A selectorized dumbbell has a handle that comprises a selector receiver and a hand grip that are separated from one another to allow a weight selector to be installed in the selector receiver. The position of the weight selector in the selector receiver determines how many of a plurality of nested weights are joined to the handle to thereby select the exercise mass of the dumbbell. After the weight selector is so installed, the hand grip is dropped into the selector receiver and is joined thereto by a connector so that the selector receiver and hand grip then act as a unitary handle to permit exercise with the selected number of weights. When so installed, the hand grip telescopically fits into the weight selector to affirmatively prevent the weight selector from inadvertently dislodging.

Abstract: A kettle bell including a weighted mass and a handle or grasping ring extending from an upper portion of the mass, and at least one opening or receiver formed through at least a portion of the mass and/or handle. In example embodiments, the at least one opening or receiver is provided for accommodating interengagement with the end male receivers of a barbell or other exercise device. In other example embodiments, one or more portions of the kettle bell is at least partially deformable or flexible.

Abstract: A dumbbell having a shaft, first and second dumbbell heads, respectively fixedly connected to first and second ends of the shaft, a tube-shaped hollow grip rotatably arranged around the shaft having first and second ends. An inner diameter of the grip is greater than an outer cross-sectional dimension of the shaft. The dumbbell further having a first ball bearing and a second ball bearing, wherein an outer ring of the first ball bearing is connected to the first dumbbell head, and an inner ring of the first ball bearing is fixedly arranged to the first end of the hollow grip, and an outer ring of the second ball bearing is connected to the second dumbbell head, and an inner ring of the second ball bearing is fixedly arranged to the second end of the hollow grip.

Abstract: An exercise device includes a resilient compression member configured to resist a compressive force from a user, and a resilient tension member configured to couple to opposing sides of the compression member. The resilient tension member is also configured to form a first portion of a loop around the compression member and the user, and resist a tensile force from the user. The exercise device also includes an extension member configured to connect with opposing ends of the tension member to form a second portion of the loop around the compression member and the user.

Abstract: A therapeutic walking trainer with a foot receiving portion for receiving at least a sub-region the forefoot of a user or for forming a connection with a toe of a shoe, having at least one main carrier which can be displaced in and/or counter to an adjustment direction, and with an actively and/or passively operable adjustment unit for the relative adjustment, oriented essentially perpendicular to the adjustment direction, of the foot receiving portion relative to the at least one main carrier.

Abstract: A wall-mounted collapsible exercise system which is adjustable between a collapsed position against a wall and an expanded position for use in multiple exercise configurations. The wall-mounted collapsible exercise system generally includes a mount support adapted to be connected to a wall, a body support adapted to support an exerciser, and a base support adapted to support the body support when the body support is in use. The body support may be pivotably connected to the mount support and the base support may be pivotably connected to the body support such that the body support and base support are adjustable between a first collapsed position for storage and a second expanded position for use. When in the expanded position, the body support may be converted between a glute ham developer configuration and a reverse hyper configuration through use of various exercise attachments.