Abstract: A pulse wave measurement electrode unit (200) includes electrodes (41 to 46) including a pair of current applying electrodes and a first pair of voltage measuring electrodes; a support member (210) that supports the electrodes on a first main surface (211) that faces a body surface of a measurement subject in a case that the pulse wave measurement electrode unit is attached on the measurement subject; and a fluid bag (24) configured to expand and contract and configured to expand upon measurement to press the electrodes (41 to 46) against the body surface of the measurement subject. The support member (210) includes a length direction (L) corresponding to a circumferential direction of the device in an attached state to the measurement subject and a width direction (W) orthogonal to the length direction (L) and a thickness direction. The electrodes (41 to 46) are arranged side by side in the width direction (W).

Abstract: An intracranial pressure monitoring device includes a housing defining a first internal chamber, a plurality of strain gauges disposed on an inner surface of a diaphragm defined by a wall of the first internal chamber, a device for generating orientation signals, and circuitry coupled to the plurality of strain gauges and to the device. The circuitry is configured to generate intracranial pressure data from signals received from the plurality of strain gauges, generate orientation data based on the orientation signals received from the device, and store the intracranial pressure data and the orientation data in a computer readable storage such that the intracranial pressure data and orientation data are associated with each other.

Abstract: A method measures intolerances in a subject to various factors, such as food, beverage, metals and minerals, nutrients, and environmental factors using a testing machine that measures bioresonance, radionics, and/or quantum response.

Abstract: A method and system for visualization of electrophysiology information sensed by electrodes on a catheter, includes recording times of electrode signal acquisition, designating a reference electrode signal acquisition, assigning a relative time to each recorded time of electrode signal acquisition relative to the reference electrode signal acquisition, identifying the electrodes with signal acquisition, correlating assigned relative times to identified electrodes to generate a sequence of electrode signal acquisitions, and generating a visual representation of the sequence of electrode signal acquisitions generating a visual representation with a graphical image of the electrodes, wherein individual electrodes are visually marked to represent the sequence of electrode signal acquisitions.

Abstract: A non-transitory computer-readable medium stores instructions readable and executable by at least one electronic processor (20) to perform an atrial fibrillation (AF) detection method (100). The method includes: generating a time-frequency representation of an electrocardiogram (ECG) signal acquired over a time interval; processing the time-frequency representation using a neural network (NN) (32) to output probabilities for rhythms of a set of rhythms including at least atrial fibrillation; assigning a rhythm for the ECG signal based on the probabilities for the rhythms of the set of rhythms output by the neural network; and controlling a display device (24) to display the rhythm assigned to the ECG signal.

Abstract: The medical toilet includes a first, second, and third electrocardiogram (EKG) lead for collecting EKG measurements from a user while seated on the medical toilet. The toilet may include arm rests, each an EKG leads placed on or within it. The arm rests may include hand grips, each hand grip including one of the EKG leads. The arm rests may have finger slips which include EKG leads. The arm rests may each have a wrist strap which includes one of the EKG leads. The first and second EKG leads may be on a toilet lid. The third EKG lead may be placed on the base of the toilet where a user may place an ankle or it may be on a toilet seat. Alternatively, the third EKG lead may be on a foot pad or within an ankle wrap. A chest strap may include additional EKG leads.

Abstract: A medical probe includes an insertion tube for insertion into a patient body, at least an arm, which is attached to a distal end of the insertion tube, at least a reference electrode coupled to the arm, and multiple electrodes, which are coupled to the arm, surround the reference electrode and are configured to sense electrical signals of body tissues that, when measured relatively to the reference electrode, are indicative of anatomical signals in the patient body.

Abstract: A catheter with basket-shaped electrode assembly with spines configured for hyper-flexing in a predetermined, predictable manner when a compressive force acts on the assembly from either its distal end or its proximal end. At least one spine has at least one region of greater (or hyper) flexibility that allows the electrode assembly to deform, for example, compress, for absorbing and dampening excessive force that may otherwise cause damage or injury to tissue wall in contact with the assembly, without compromising the structure and stiffness of the remaining regions of the spine, including its distal and proximal regions. The one or more regions of greater flexibility in the spine allow the spine to flex into a generally V-shape configuration or a generally U-shape configuration.

Abstract: A physiological signal sensor is provided, which includes an electrode layer, a pressure detection layer and a controller. The electrode layer is disposed on the skin of a subject to detect a physiological signal therefrom. The pressure detection layer detects the pressure signal of the electrode layer. The controller is connected to the electrode layer and the pressure detection layer; the controller outputs the physiological signal and outputs a measurement prompt signal according to the pressure signal.

Abstract: A method of performing magnetic resonance imaging of a body includes a) immerging the body in a static and substantially uniform magnetic field; b) exciting nuclear spins inside the body using at least one radio-frequency pulse; c) applying to the body a time-varying magnetic field gradient defining at least one trajectory (ST) in k-space and simultaneously acquiring samples of a magnetic resonance signal so as to perform a pseudo-random sampling (KS) of the k-space; and d) applying a sparsity-promoting nonlinear reconstruction algorithm for reconstructing a magnetic resonance image of the body; wherein, at least in a low-spatial frequency region of the k-space, the distance between any two adjacent points belonging to a same trajectory is lower than 1/FOV, FOV being the size of a field of view of the reconstructed image. A magnetic resonance imaging apparatus for carrying out such a method is also provided.

Abstract: In a magnetic resonance imaging method, a first adjustment parameter is determined for presetting an initial contrast of a magnetic resonance image; a second adjustment parameter is determined for obtaining an optimized contrast of the magnetic resonance image and a specified data acquisition time of a blade artifact correction sequence; an optimized echo signal evolution curve is determined according to the first adjustment parameter and the second adjustment parameter; an actual variable flip angle train is calculated according to the optimized echo signal evolution curve; and the actual variable flip angle train is applied to a two-dimensional fast spin echo sequence, and the blade artifact correction sequence corresponding to the second adjustment parameter is used to acquire magnetic resonance signals and enable the magnetic resonance image to satisfy the optimized contrast.

Abstract: Various examples are directed to systems and methods for operating an analyte sensor system using sensor electronics. An example method may comprise applying a bias voltage change to an analyte sensor bias voltage and measuring a current value for each of a plurality of time periods after application of the bias voltage change. The example method may also comprise determining an estimated impedance using the current values for the plurality of time periods and determining a characteristic of the analyte sensor using the estimated impedance. The example method may further comprise receiving from the analyte sensor a signal indicative of an analyte concentration, and determining an estimated analyte concentration level using the determined characteristic of the analyte sensor and the received signal.

Abstract: A system and method for locating a medical device within a body uses wireless technology to transmit the information obtained from the sensors to a mobile device or other computing system. A software application on the mobile device or computing system can be used to display the information, wherein the user can control the display without needing to contact any items that are not sterile.

Abstract: The present invention provides a gastrointestinal tract positioning switch, a method of manufacturing the gastrointestinal tract positioning switch and a site-specific delivery capsule. The gastrointestinal tract positioning switch includes a base, a first electrode, a second electrode, a conductive device and a positioning film. The first electrode and the second electrode are spaced apart from each other and fixed on the base. The first electrode and the second electrode electrically connected to the conductive device respectively, and covered by the positioning film. Both the first electrode and the second electrode are an inert electrode, and can be exposed after dissolution or/and degradation of the positioning film in the stomach or intestine.

Abstract: Various embodiments of a video-based fall risk assessment system are disclosed. During operation, this fall risk assessment system can receives a sequence of video frames including a person being monitored for fall risk assessment. The system next generates a sequence of action labels for the sequence of video frames by, for each video frame in the sequence of video frames: estimating a pose of the person within the video frame; and classifying the estimated pose as a given action among a set of predetermined actions. Next, the system identifies a subset of action labels within the sequence of action labels. The system next extracts a set of gait features for the person from a subset of video frames within the sequence of video frames corresponding to the subset of action labels. Subsequently, the system analyzes the set of extracted gait features to generate a fall risk assessment for the person.

Abstract: This disclosure relates to a system and method to analyze balance and stability of a patient. Test data for the patient, representing motion of a device affixed to the patient during a test interval, can be received. The test data can be processed to provide processed data (or sensor-derived data) that includes at least one of acceleration data, rotational rate data and rotational position data for the test interval. A biomechanical model can be applied to the processed data to provide center of mass (COM) motion data representing movement of the COM in multiple dimensions for the patient during the test interval. An indication of balance for the patient can be determined based on the COM motion data. The indication of balance can be used to analyze the balance and stability of the patient.

Abstract: Embodiments generally relate to a method of assessing the hearing of a patient using functional near-infrared spectroscopy (fNIRS). The method comprises receiving at least one response signal from an optode placed on a scalp of the patient, the response signal comprising fNIRS data generated by the optode and relating to an aural stimulation received by the patient; comparing at least one parameter of the at least one response signal to a predetermined parameter value; and determining an auditory response of a patient based on the at least one parameter of the at least one response signal.

Abstract: A method of assessing the effect of viewing varying colours of light on a subject's perception of tinnitus, comprising the steps of: presenting a display in at least part of the subject's Held of view; illuminating the display with coloured light in the visible spectrum using one or more variable sources, varying measurable values of the coloured light illuminating the display; and recording the measurable values of the coloured light illuminating the display at which the subject indicates a change in their perception of tinnitus.

Abstract: Various examples described herein are directed to systems and methods for determining an analyte concentration using an analyte sensor. A method may comprise disconnecting an analyte sensor from a measurement circuit and reconnecting the analyte sensor to the measurement circuit after an accumulation period. The method may comprise receiving a signal from the analyte sensor. The signal may be indicative of an amount of charge accumulated on the analyte sensor during the accumulation period. The method may also comprise determining an estimated analyte concentration level based on the received signal.

Abstract: Various examples are directed to systems and methods of and using analyte sensors. An example analyte sensor system comprises an analyte sensor and a hardware device in communication with the analyte sensor. The hardware device may be configured to perform operations comprising applying a first bias voltage to the analyte sensor, the first bias voltage less than an operational bias voltage of the analyte sensor, measuring a first current at the analyte sensor when the first bias voltage is applied, and applying a second bias voltage to the analyte sensor. The operations may further comprise measuring a second current at the analyte sensor when the second bias voltage is applied, detecting a plateau bias voltage using the first current and the second current, determining that the plateau bias voltage is less than a plateau bias voltage threshold, and executing a responsive action at the analyte sensor.

Abstract: The present invention relates to a personal health monitoring system comprising an implantable sensor and a monitoring device. The present invention further relates to a multiple user health monitoring system comprising a plurality of such personal health monitoring systems. The present invention further relates to a method of monitoring the biological parameters of at least one user.

Abstract: Systems and method are described for determining if a decision support recommendation is to be presented to a user for treatment of a diabetic state, including receiving a plurality of input data items impacting a diabetic state of a user of continuous glucose monitor, the input data items serving as input data to a process for determining a decision support recommendation; assigning a reliability level to each of the input data items; calculating a reliability metric based on the reliability levels assigned to each of the input data items; determining a decision support recommendation based on the process and the input data and presenting the decision support recommendation to the user on a user interface only if the reliability metric exceeds a threshold.

Abstract: Various examples described herein are directed to systems, apparatuses, and methods for mitigating break-in in an analyte sensor. An example analyte sensor system comprises an analyte sensor applicator comprising a needle; an analyte sensor comprising at least a working electrode and a reference electrode, the analyte sensor positioned at least partially within a lumen of the needle; and a hydrating agent positioned within the lumen of the needle to at least partially hydrate the needle.

Abstract: An analyte sensor comprising: an insertion tip configured for insertion below a tissue of a user, the insertion tip comprising: a working electrode comprising a sensing layer disposed thereon and a membrane layer disposed at least partially over the sensing layer; a substrate; and a counter electrode. Wherein a polymer layer comprising at least an immunosuppressant is disposed on an exterior surface of the working electrode, the substrate, or the counter electrode, the polymer layer being separate from the sensing layer and the membrane layer.

Abstract: A method for photoplethysmography measurement couples a color camera in optical contact against a skin surface of a subject and couples at least a first solid-state illumination source in optical contact against the skin surface, wherein the first solid-state illumination source has a first wavelength range with a first bandwidth that exceeds 50 nm. The illumination source and color camera are energized over a predetermined time interval to acquire a first sequence of image frames from the skin surface. A set of hue values is computed from each of the acquired sequence of image frames and photoplethysmography data generated according to periodic changes in an average hue per frame computation. The generated photoplethysmography data is presented on a display.

Abstract: A suction applying device (10) for applying suction to a sampling unit (50) for sampling bodily fluid, wherein the suction applying device comprises a syringe body (12) with a hollow interior (14) and a piston (20) movable inside the hollow interior of the syringe body. The syringe body has a rear end (16) through which a piston rod (21) connected to the piston extends outside of the syringe body and by means of which the piston can be moved, and a front end (18) opposite the rear end. The suction applying device further comprises a connection arrangement (130) configured for connection of a sampling unit, wherein the connection arrangement is located at the front end of the syringe body.

Abstract: A monitoring system for generating a mental state indicator for use in identifying a mental state of a biological subject, including one or more electronic processing devices that obtain subject data indicative of at least a heart rate measured for the biological subject during at least part of a sleep episode, analyze the subject data to determine at least one sleep segment; analyze the subject data to determine at least one metric for the at least one sleep segment, and apply the at least one metric to a computational model to determine a mental state indicator indicative of a mental state, the computational model embodying a relationship between different mental states and one or more metrics, and being obtained by applying machine learning to reference metrics derived from heart rates measured for one or more reference subjects during at least part of a reference sleep period.

Abstract: A system for analyzing eye movement on the basis of brain function and a device using the same, wherein the eye movement analysis system comprises: an eye movement behavior pattern and a plurality of eye movement data collection and data storage modules. The eye movement data collection is used to perform real time analysis on position data of the head and eyes, so as to compensate for the impact of head motion on eye position, thereby ensuring more accurate results. The device using this system is applicable to the diagnosis of neurodegenerative diseases.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for causing a stimulus presentation system to present first content to a patient. Obtaining, from a brainwave sensor, electroencephalography (EEG) signals of the patient while the first content is being presented to the patient. Identifying, from within the EEG signals of the patient, first brainwave signals associated with a first brain system of the patient, the first brainwave signals representing a response by the patient to the first content. Determining, based on providing the first brainwave signals as input features to a machine learning model, a likelihood that the patient will experience a type of depression within a period of time. Providing, for display on a user computing device, data indicating the likelihood that the patient will experience the type of depression within the period of time.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for presenting a human participant with information known to stimulate a person's neural reward system. Receiving an EEG signal from a sensor coupled to the human participant in response to presenting the participant with the information, the EEG signal being associated with the participant's neural reward system. Contemporaneously with receiving the EEG signal, receiving contextual information related to the information presented to the human participant. Processing the EEG signal and the contextual information in real time using a machine learning model trained to associate depression in the person with EEG signals associated with the person's neural reward system and the presented information. Diagnosing whether the participant is experiencing depression based on an output of the machine learning model.

Abstract: Described herein is a method of using functional MRI (fMRI) for determining brain activation patterns for a group of subjects in response to different odor-elicited feelings (i.e., conscious emotions). A method for preparing a perfume by using the method of the present invention and a consumer product including said perfume are also described herein.

Abstract: An impression measurement device is provided with an acquisition unit that, in a case in which a user interviews multiple persons in an order, acquires biological information of the user during the interview with each of the multiple persons, a setting unit that, in a case of deciding weight values assigned to the biological information acquired by the acquisition unit for each of the multiple persons, sets larger weight values for later persons compared to earlier persons in the order, and a correction unit that uses the weight values set by the setting unit to correct the biological information of the user with respect to each of the multiple persons.

Abstract: An object is to provide a technique capable of accurately determining an awakening degree. An awakening degree determination apparatus includes a change amount acquisition unit, a frequency calculation unit, and an awakening degree determination unit. The change amount acquisition unit acquires an angle change amount, an inclination change amount, and a position change amount. The frequency calculation unit calculates an angle frequency, an inclination frequency, and a position frequency. When at least one of the angle frequency, the inclination frequency, and the position frequency exceeds a fourth threshold value, a fifth threshold value, and a sixth threshold value, the awakening degree determination unit determines that an awakening degree of a driver of the vehicle decreases.

Abstract: The present invention provides a method and system for monitoring driver inattentiveness using plurality of physiological factors of the driver. In this method, captured images and/or short videos are used to determine the physiological factors of the driver. The first physiological factor from the plurality of physiological factors is used to determine the level of drowsiness and/or inattentiveness of the driver, which further supported by the second physiological factor. The data generated from the analysis of first and second physiological factors is further utilized to generate a predictive warning to the driver. The intensity level of the warning is varied based on the analyzed level of inattentiveness of the driver. The warning may be an audio warning, a visual warning, an audio-visual warning, haptic warning like vibration, etc.

Abstract: A urine collecting and analyzing apparatus that mounts on a toilet. The apparatus has a housing that mounts to or is integrated into the rim of the toilet bowl and has an opening for access to the bowl. The housing has a collector compartment and a controller compartment. A collector cup fits under the collector compartment extends over the bowl in a retracted position and in a collecting position. When in the collecting position, the cup captures urine released by a user. The cup is connected to a measurement chamber by a transfer tube. The urine moves through the transfer tube from the cup to the measurement chamber to a predetermined threshold volume and level. A controller in the controller compartment reads sensors and transmits sensor data to a device for storage and display.

Abstract: An oxygen-sensing assembly for attachment to a urinary catheter may include a housing having a flow pathway extending between an inlet end and an outlet end thereof, an oxygen sensor in operable communication with the flow pathway of the housing, the oxygen sensor configured to detect oxygen levels of a fluid flowing through the flow pathway and a flowrate sensor configured to detect a flowrate of the fluid flowing through the flow pathway. A risk of acute kidney injury may be determined based on the mass flowrate of oxygen through the flow pathway, determined based on the detected oxygen levels and the flowrate of the fluid through the flow pathway. Related catheter assemblies and methods are also disclosed.

Abstract: A method and a system for action monitoring of reciprocating sport are provided. The monitoring method is adapted for a monitoring system including a calculation apparatus, at least one gravity sensor disposed on at least one motion part of a human body and at least one electromyography sensor disposed on at least one muscle part of the human body. The method includes: in a process of a reciprocating sport involving multiple actions performed by the human body, sensing a relative angle of each motion part with respect to a reference position of the human body by the gravity sensor and sensing a startup sequence of the muscle part by the electromyography sensor; determining the action performed by the human body according to the relative angle; and determining whether a force applied by the human body is correct according to the action and the startup sequence of the muscle part.

Abstract: Systems, devices and methods are provided for acquiring, validating and analyzing athletic movement data. Generally, a sensor device, such as a force plate, is provided for sensing certain characteristics of an athletic movement. A local computing device coupled to the sensor device can be configured to receive sensor data indicative of the characteristics of the athletic movement, process and extract information from the sensor data, and transmit the processed sensor data to a remote server system. The remote server system can be configured to store, aggregate and update the processed sensor data in a database, and can also generate one or more normalized scores correlating to the athletic movement. The normalized scores can indicate to a user a susceptibility to injury, progression towards return to play or propensity for success with respect to a particular sport.

Abstract: A wearable device for multiplexed sweat analysis includes a sensing module. The sensing module includes multiple compartments, including a first compartment configured to induce sweat and sense a target analyte, and a second compartment configured to induce sweat and sense the target analyte.

Abstract: Devices and processes for maintaining a narrow body lumen are described. One embodiment of the inventive device includes: (i) a hydraulic propulsion mechanism for propelling an imaging portion or a therapeutic portion through the narrow body lumen; and (ii) a retrieval mechanism for retrieving the imaging portion or the therapeutic portion from the narrow body lumen.

Abstract: The following disclosure discusses systems and methods of detecting and analyzing cutaneous conditions. According to one embodiment, a 2D image of the cutaneous condition and a set of 3D point clouds associated with the 2D image are captured using an image capturing device. The 2D image and the set of 3D point clouds are sent to a computing device. The computing device generates a 3D surface according to the set of 3D point clouds. Subsequently, the computing device receives a depth map for the 2D image based upon the 3D surface from another computing device such that the depth map comprises depth data for each pixel of the 2D image. The cutaneous condition may then be measured and analyzed based upon the depth map using the computing device.

Abstract: Various embodiments of the present invention relate to an electronic device and a stress measurement method thereof. The electronic device comprises: a memory for storing a first histogram for determining reference information for computing health condition of a user; a biometric sensor; and at least one processor functionally connected to the memory and the biometric sensor, wherein the at least one processor may be configured to acquire biometric information via the biometric sensor, generate a second histogram by analyzing the acquired biometric information, accumulate the second histogram in the first histogram, thereby updating the first histogram, and update the reference information on the basis of the updated first histogram. Other various embodiments are possible.

Abstract: A software and hardware system is described that enables effective lifestyle management by providing a dynamic assessment of a user's physical and behavioral metrics via a high feedback ratio interface.

Abstract: An electronic device according to various embodiments comprises: a bio-signal detection sensor configured to acquire first and second biometric information on an object outside the electronic device; and a processor, wherein the processor can be configured to: acquire the first and second biometric information by using the bio-signal detection sensor; configure a first variance, in which the first biometric information is changed, and a second variance, in which the second biometric information is changed; determining a state of the object related to the sleep on the basis of at least a part of the first variance and the second variance; and estimate a sleep latency related to the object on the basis of at least a part of the state.

Abstract: A personalized parameter learning method, a sleep-aid device and a non-transitory computer readable medium are provided. The personalized parameter learning method for a sleep-aid device is provided. The personalized parameter learning method includes the following steps. A process device computes a measured sleep quality of a user after operating a sleep-aid device with an inputted parameter setting at least according to a subjective feedback from the user. The processing device generates a plurality of candidate parameter settings according to the measured sleep quality. The processing device generates a plurality of predicting sleep qualities corresponding the candidate parameter settings. The processing device obtains a recommending parameter setting by selecting one of the candidate parameters according to the predicting sleep qualities.

Abstract: The present disclosure pertains to optimizing sleep score parameters. In one embodiment, a first set of vectors is obtained, where each vector includes parameter values of sleep-related parameters for calculating a sleep score. For each vector of the first set, a correlation value indicating a degree of a correlation between the vector and a user-indicated sleep score associated with a set of parameter values representative of a sleep metric of the user is determined. A second set of vectors is generated based on a first subset and a second subset of the first set of vectors satisfying a first and second criteria, respectively. A correlation value associated with each vector of the second set is determined. For each sleep-related parameter, a parameter value of a given vector of the second set is assigned based on the correlation values associated with the second set.

Abstract: This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a SMAD7 inhibitor.

Abstract: An implant installation strength evaluation method includes a step of vibrating an implant, a step of measuring time series data of the number of vibrations and vibration strengths of the implant vibrated in the vibrating step, and a step of deriving information indicating an index of an installation strength of the implant based on the time series data of the number of vibrations and vibration strengths of the implant.

Abstract: Methods, systems and devices for aligning measurement data sets from different devices. In one embodiment, a synchronization platform includes circuitry configured to establish a first communication link with a first device being worn at a first location on a body of a user, receive a first set of measurement data from a first sensor of the first device indicative of physiological measurements of the user. The circuitry is further configured to: establish a second communication link with the second device, receive a second set of measurement data of the first type from a second sensor of the second device indicative of the physiological measurements of the user, and align the second set of measurement data with the first set of measurement data, wherein the second set of measurement data is a continuation of the first set of measurement data.

Abstract: A clip configured to be coupled to an electrocardiogram sensor unit. The clip includes an electrically conductive material having a first surface and a second surface opposite the first surface. The clip also includes electrical insulation coupled to the second surface of the electrically conductive material, and an electrode defined by an exposed portion of the first surface of the electrically conductive material. The clip may be flexible or substantially rigid.