Abstract: A method for external ear canal pressure regulation to alleviate one or more symptoms associated with a disorder or treat one or more disorders, the method including providing a fluid transfer device which generates a fluid flow of a fluid through an earplug, the earplug having an earplug external surface configured to sealably engage an external ear canal wall as a barrier between an external ear canal pressure and an ambient pressure; sealably engaging the earplug of the fluid transfer device with the external ear canal wall as the barrier between the external ear canal pressure and the ambient pressure; and operating the fluid transfer device to generate the fluid flow of the fluid through the earplug to achieve an external ear canal pressure differential between the external ear canal pressure and the ambient pressure effective to alleviate a disorder symptom or treat a disorder.

Abstract: A fibrin-coated wound dressing article having a flexible film layer, a pressure-sensitive adhesive layer disposed on the flexible film layer, and a fibrin powder layer disposed on a surface of the pressure-sensitive adhesive layer opposite the flexible film layer. Methods of making and using fibrin-coated wound dressing articles are included.

Abstract: A nonwoven fabric. The nonwoven fabric can include a first surface and a second surface and a visually discernible pattern of three-dimensional features on one of the first or second surface. Each of the three-dimensional features can define a microzone comprising a first region and a second region. The first and second regions can have a difference in values for an intensive property, and wherein in at least one of the microzones, the first region exhibits a Contact Angle of greater than 90 degrees, as measured by the Contact Angle Test Method detailed herein, and the second region exhibits a Time to Wick of less than 10 seconds, as measured by the Time to Wick Test Method detailed herein.

Abstract: The present invention relates to a method and apparatus for forming a composite structure, preferably for use in an absorbent structure used within the personal hygiene industry, such as for instance feminine hygiene garments, baby diapers and pants and adult incontinence garments. The present invention preferably provides a method and apparatus for depositing and positioning particulate materials in a desired pattern onto a moving carrier layer. The method allows accurate forming of a pattern of particulate material clusters at high production speed having improved attachment properties, with reduced raw material usage and relative low cost. The present invention foresees in the need for improved thin, flexible, lightweight absorbent structure having optimal absorption, distribution and retention.

Abstract: A top sheet includes a skin contact surface configured to contact the skin of a wearer. The skin contact surface includes at least one projection and at least one recess. The top sheet further includes a back surface opposite the skin contact surface. The top sheet further includes a coating on the at least one projection. The coating essentially includes a blood slipping agent having a kinematic viscosity of 0.01 to 80 mm2/s at 40° C., a water holding percentage of 0.01 to 4.0 mass %, and a weight-average molecular weight of less than 1,000, and the coating is configured to slip from the skin contact surface, through the top sheet, to the back surface along with menstrual blood.

Abstract: A sanitary napkin (1) includes an absorbent (4) interposed between a liquid permeable top sheet (3) and a back sheet (2), wherein the liquid permeable top sheet (3) has multiple protruding parts (10) that protrude towards a skin side and that are formed at intervals, embossed parts (11) compressed from the skin side, and opening parts (12) that penetrate the liquid permeable top sheet (3), the embossed parts (11) and opening parts (12) being formed, around the protruding parts (10), to be separate from each other. Skin side extending parts (13) are provided at peripheries of the opening parts (12) such that the skin side extending parts (13) protrude towards the skin side at heights lower than heights of the protruding parts (10).

Abstract: The present invention relates to a unitary absorbent structure and method thereof wherein said unitary absorbent structure comprises an absorbent core (5) and/or an acquisition (2) and dispersion (3) layer, said absorbent core (5) and/or an acquisition (2) and dispersion (3) layer comprising at least one non-woven fibrous substrate layer (23) having a void volume suitable to be penetrated by super absorbent particles, characterized in that said super absorbent particles are dispersed in the substrate layer (23) according to a size distribution gradient along the depth direction or z-direction of said absorbent core (5) and/or acquisition (2) and dispersion (3) layers.

Abstract: An adaptable rugged illumination system for use with an emergency medical stretcher. The illumination system illustratively includes a light source, wherein the emitted light may be controlled based upon detected movement of the stretcher.

Abstract: The presently disclosure describes a system for stabilizing a wheelchair. The system includes at least one caster arm configured to maintain contact with a surface underlying the wheelchair. The at least one caster arm includes a force sensing system configured to measure a force exerted on the underlying surface by the at least one caster arm; and an actuator to configured adjust a position of the at least one caster arm based at least in part on the measured force.

Abstract: A caster wheel suspension assembly for a wheelchair or the like includes a housing with a clevis portion and a tubular portion; a fork member pivotably mounted in the clevis portion of the housing, the fork member having a pair of fork arms extending from the housing, each of the fork arms terminating in a lower end, the fork member having an upper portion formed as a clevis tang disposed in the clevis portion of the housing; a damping element in the tubular portion of the housing; and a compression adjustment element connected to the clevis pin and extending axially through the damping element. The compression adjustment element is configured to apply an adjustable compressive force to the damping element, and it is further configured to be moved axially within the tubular portion of the housing for adjustment of the compressive force applied to the damping element.

Abstract: An embodiment can include a suspension system for a powered wheelchair, the suspension system comprising an arm and an air suspension subsystem. The air suspension subsystem in this embodiment can comprise a coil spring and an air bag surrounded by the coil spring. The arm in this embodiment can be configured to (a) couple a drive axle to a frame of the powered wheelchair and (b) move the drive axle relative to the frame. In this embodiment, a first end of the drive axle can be coupled to a wheel of the powered wheelchair, while the frame is closer to a second end of the drive axle than the first end, and the first end of the drive axle is opposite the second end of the drive axle. A first end of the air suspension subsystem in this embodiment can be coupled to the frame when a second end of the air suspension subsystem is coupled to the arm and the second end of the air suspension subsystem is opposite the first end of the air suspension subsystem. Other embodiments are disclosed.

Abstract: A linkage assembly that connects a sling bar to a person lift apparatus includes a link body that connects to the person lift apparatus. The link body has a keyed slot extending therethrough. The keyed slot has a region of reduced dimension. An interlocking member connects to the sling bar. The interlocking member has an interlocking portion that is sized to be slidably received in the keyed slot. The interlocking portion has a region of reduced dimension such that, in an interlocked orientation, the region of reduced dimension of the interlocking portion is offset from the region of reduced dimension of the keyed slot thereby inhibiting removal of the interlocking member from the keyed slot and, in a release orientation, the region of reduced dimension of the interlocking portion is aligned with the region of reduced dimension of the keyed slot thereby allowing removal of the interlocking member from the keyed slot to disconnect the sling bar from the person lift apparatus.

Abstract: A patient repositioning apparatus doubles as a repositioning sheet and a sling. The repositioning apparatus includes a sheet with an upper surface and an opposing lower surface and defines an outer periphery that has opposing side edges. The upper surface of the sheet has an upper surface material, and the lower surface of the sheet has a lower surface material that is formed from a relatively low-friction material as compared to the upper surface material. The handles are disposed along the opposing side edges of the sheet, and the strap members are attached to the sheet and distributed across both opposing side edges. Each of the strap members includes a strap portion that forms a bight in the strap member.

Abstract: A patient repositioning device includes an upper body support and a lower body support which are generally planar and laterally spaced from one another by a spacing element. A handle can rotate in the plane of the supports, enabling a care giver to rotate a patient form a sitting to a lying position and then to roll the patient onto their back. Another embodiment provides a patient cradle for cradling a patient from a reclining to a sitting position and vice versa.

Abstract: A mobile medical office may include a desk platform including a desk surface, and a telescoping swivel arm including a fixed portion and a telescoping portion, the fixed portion operably attached to a frame and the telescoping portion pivotably attached to the desk platform such that the desk platform is adjustable from a) a collapsed configuration in which the desk platform is in a position substantially perpendicular to a seating support to b) a deployed configuration in which the desk platform is in a position substantially parallel the seating support.

Abstract: Users of body bags know and live with the technical issues that come with the reality of the manipulation of the corpse of a deceased animal or human. The simple and efficient design of this body bag is free of unnecessary structures, is expandable to adapt to various body shapes depending on species and size through two expandable gussets, is leak proof through glued side folds, presents an aperture that allows access to the entire corpse through a closable flap, is permanently identifiable through a printed identification area, is the only bag necessary for transportation, storing and disposal and is compact, sturdy, and economical. With this invention, technical issues are addressed while bringing an even more dignified look to the corpse of the deceased in the body bag for the family, the public and the professionals involved in the process.

Abstract: An orthosis includes dynamic tensioning elements, recreating and/or improving on the load sharing typically provided by soft tissue, such as ligaments, tendons, muscle and a capsule at a joint of a patient or wearer, thereby providing support and preventing further injury from joint instability and/or joint laxity. The orthosis can support a glenohumeral joint of the shoulder brace and can prevent additional injury from various shoulder instabilities, for example, anterior, inferior, posterior and/or multidirectional instabilities. This can be accomplished by dynamically tensioning posterior, anterior and/or humeral head straps of the orthosis. The straps can be primarily adjustable only in tension forces stored there within, rather in orientation relative to the shoulder. This can simplify setup and use, and can ensure the orthosis has a low profile. Related methods of use also are provided.

Abstract: A device for rehabilitating or strengthening the ankle includes a plank that is connected by a transversely oriented hinge and a longitudinally oriented pivot, as well as a pair of compression springs at its forward end. The connections of the plank to the underlying base limit the plank to motion in two directions about two axes, thereby providing four types of therapeutic ranges of motion, including dorsiflexion and plantar flexion, eversion and inversion. A transversely slidable foot rest enables the user to hold device 21 in position with one foot while using the plank of the device to rehabilitate the other foot.

Abstract: A corrugated tube includes a hollow tube formed of several crests and several troughs connected alternately. The middle of an end face of a tail end of the corrugated tube is provided with a boss; and both a first section of a head end and a last section of a tail end of the corrugated tube are crests, with the width of both the crest of the first section of the head end and the crest of the last section of the tail end being greater than the thickness of the corrugated tube, preventing the tail end and the head end of the corrugated tube from collapsing inwards when the air pressure in the corrugated tube decreases.

Abstract: A human motion assistance device has an upper torso harness for attaching to a user. The upper torso harness has a shoulder strap or backpack assembly. A belt is connected to the upper torso harness and extends around a waist and back area of the user. Leg straps are affixed to the upper torso harness proximate to a gluteal area of the user and configured to extend down a hamstring area to cross in front of a knee area and further extend down a calf area to a foot anchor. The leg straps are made of an elastic material with a pocket around the knee area of the user. The foot anchor may extend under the heel to an arch strap, or cross over the talus and under the arch of the foot. The upper torso harness and leg straps are passive without active members.

Abstract: A load-relieving apparatus includes a wire cable 36 with a free end and a fixed end opposite to the free end, a locking part 361 being attached to the free end, a winding part 334 configured to wind the wire cable 36 from a fixed-end side thereof, a pulley 335 interposed between the winding part 334 and the locking part 361, and configured to stretch the wire cable therebetween, and a cover 336 with a through hole 338H formed therein through which the wire cable 36 is inserted, the cover 336 being interposed between the locking part 361 and the pulley 335, and formed so as to cover at least a part of the pulley 335. Further, the through hole 338H is configured so that a relative position of the through hole 338H with respect to a rotation axis of the pulley 335 changes.

Abstract: An assistance apparatus includes a first and second wires coupling an upper-body belt and a left knee belt to each other on or above a front and back parts of a body of a user, respectively, a third and fourth wires coupling the upper-body belt and a right knee belt to each other on or above the front and back parts, respectively, a motor, a first sensor that detects at least tensions of the first and third wires, and a control circuit. The control circuit controls the motor to generate, when the first wire is broken, in the second wire, a tension less than a tension of the second wire during no break in the first wire, and to generate, when the third wire is broken, in the fourth wire, a tension less than a tension of the fourth wire during no break in the third wire.

Abstract: A rollator designed to provide low-radius rotational mobility while a user is engaged in motion with a foldable and height adjustable frame allowing a user to have a natural full gait. The foldable frame has an angled upright U-shaped main frame section and a base U-shaped frame section mounted to the angled upright U-shaped frame and a U-shaped intermediate frame section mounted to the angled U-shaped upright frame section and the base U-shaped frame section. A moveable seat assembly is slideably mounted to the U-shaped support assembly to assume desire positions. A pair of rear wheels are mounted to the frame and a pair of front wheels are mounted to yoke mechanisms which are mounted on the frame. A brake assembly including brake levers are mounted to the frame, the brake assembly being operatively connected to the pair of rear wheels to brake the rear wheels with each of the brake levers being adapted to transfer braking force from the user hand grip lever to the rear wheels.

Abstract: A massage device includes spaced apart first and second arms having aligned first and second pivot areas. A cross bar having a first end and a second end is attached to the first arm proximate the first end of the cross bar between the first and second pivot areas. The cross bar is attached to the second arm proximate the second end of the cross bar between the first and second pivot areas. A massage element is carried by the cross bar.

Abstract: The invention provides a compression device for the limb of a mobile patient. The device includes an inflatable sleeve adapted to surround the limb; a conduit attached to the sleeve for delivering fluid to the sleeve; and a portable, wearable controller attached to the conduit that generates and controls the flow of fluid in the device.

Abstract: A device can comprise: a trigger chamber, having a trigger elastic wall and a trigger base wall, the trigger chamber configured for relative motion between the trigger elastic wall and the trigger base wall; a connecting line fluidly coupled to the trigger chamber, the connecting line having a substantially inelastic wall; a stimulation chamber fluidly coupled to the connecting line, the stimulation chamber having a stimulation elastic wall and a stimulation base wall, the stimulation chamber configured for relative motion between the stimulation elastic wall and the stimulation base wall, the stimulation elastic wall having an exterior surface; a plurality of projections coupled to the exterior surface; and a stabilizing frame, the stabilizing frame having a substantially rigid wall, the stabilizing frame having a plurality of apertures, the stabilizing frame extending over the stimulation chamber, the projections configured to extend through the apertures when the stimulation chamber is expanded.

Abstract: A device is provided for vibrational stimulation of body tissue in body cavities which are difficult to access, particularly in the nasal cavity. The device includes an expandable stimulation member, which can be introduced via a body opening into a body cavity. In an expanded state of the device, the stimulation member abuts against the body tissue within the body cavity. To accomplish vibrational stimulation, the stimulation member is brought to vibrate at a frequency of 48-70 Hz within the body cavity. A method is also provided for vibrational stimulation of body tissue in a body cavity, particularly in the nasal cavity of a patient.

Abstract: The present invention is a method for improving hemodynamics and clinical outcome of patients suffering cardiac arrest and other low-flow states by combination of circumferential constriction and anteroposterior compression decompression of the chest cardiopulmonary resuscitation. Anteroposterior compression decompression may be provided by a piston mechanism attached to a gantry above the patient. Circumferential constriction may be achieved by inflation of pneumatic bladders or shortening of a band. The on-off sequence and relative force of circumferential constriction and anteroposterior compression decompression may be adjusted so as to improve efficacy.

Abstract: A device for storing pharmaceuticals that includes a bottom portion having wells and a lid having correlating well covers. The wells and cover are manufactured from an insulating material which protects the medication from heat and moisture. The bottom portion and lid preferably includes matching tabs to assist the user in lining up the lid with the bottom. The device may include a child resistant rim on the bottom portion that “locks” the lid onto the device when it is closed. The lid of the device may include a protrusion which interlocks with a complimentary indentation in the bottom of an additional device to allow for easy transport of additional pharmaceuticals. The device may further include a hanger hole for easy transport of the device.

Abstract: A container storing a liquid anesthetic solution is disclosed. The container is sealed by a closure, and the liquid anesthetic solution includes an anesthetic being from 0.1% to 10% by weight of the liquid anesthetic solution, water, and a solvent. The container includes a material that is inert to the anesthetic, and the closure includes siliconized rubber, a fluoropolymer, or metal that is inert to the anesthetic. The concentration of the anesthetic in the liquid anesthetic solution stored in the container following a predetermined time period is at least 93% of a concentration of the anesthetic in the liquid anesthetic solution before the liquid anesthetic solution is stored in the container.

Abstract: Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.

Abstract: Liquid drug transfer devices including an integral telescopic vial adapter for telescoping from an initial pre-compacted state to a final compacted state. In the initial pre-compacted state, the vial adapter telescopically snap fits on an initially non-punctured intact discrete injection vial leaving its injection vial stopper non-punctured. In the final compacted state, the vial adapter punctures the injection vial stopper. The liquid drug transfer device is used with an intact discrete injection vial release tool for applying a pincers-like compression for convenient release of a non-punctured intact discrete injection vial in the initial pre-compacted state. The vial adapter includes a clamping arrangement for irreversibly clamping same in the final compacted state. The vial adapter precludes release of a punctured discrete injection vial in its final compacted state.

Abstract: Liquid transfer devices with an integral telescopic vial adapter for use with an infusion liquid container and an initially non-punctured intact discrete injection vial. The integral telescopic vial adapter is configured for initial telescopic snap mounting on a discrete injection vial leaving its injection vial stopper non-punctured until a subsequent compaction for puncturing the injection vial stopper. The integral telescopic vial adapter includes a safety catch mechanism for precluding advertent compaction from a pre-compacted state to a compacted state. The integral telescopic vial adapter includes a clamping arrangement for irreversibly clamping same in its final compacted state.

Abstract: A pump drive for an automatic drug compounder may be provided. The pump drive may include a pump head assembly with a plurality of operational mechanisms controllable to operate a pump cartridge to pump fluids through the cartridge to a vial containing a drug, or to pump a reconstituted drug to a receiving container. The pump drive may include a vial lift vial grip configured to retrieve the vial from a vial tray and lift the vial such that a needle assembly of the pump cartridge extends into the vial through sealing membranes of the cartridge and a vial puck attached to the vial. The pump head assembly may be rotatable to agitate and/or invert the vial. The operational mechanism may include an eccentric drive for driving a piston pump of the cartridge and a plurality of valve actuators for operating valves of the pump cartridge.

Abstract: A disposable pump cartridge for a compounder system is provided. The cartridge may include a plurality of controllable fluid pathways and a piston for pumping fluid and/or vapors through selected ones of the fluid pathways. The cartridge may include a plurality of valves operable to select particular pathways from the plurality of pathways. The fluid pathways may be formed from a portion of a cartridge frame and a sealing membrane disposed on the cartridge frame. A cartridge bezel disposed over the sealing membrane may include openings that provide access to the valves. The valves and the piston may be operated by a pump drive of the compounder system. The bezel may include additional openings that provide access to ports within the cartridge for receiving diluents or for providing waste. Portions of the sealing membrane within the additional openings in the bezel may be configured to receive a needle therethrough.

Abstract: According to one embodiment, a tablet printing apparatus includes: a conveyor belt configured to convey a tablet; a first suction path configured to suck the tablet to hold the tablet on the conveyor belt and suck the conveyor belt while allowing the conveyor belt to convey the tablet; a second suction path configured as a different path from the first suction path to suck only the conveyor belt while allowing the conveyor belt to convey the tablet; and a printer configured to perform printing on the tablet conveyed by the conveyor belt.

Abstract: A cutting device includes a first blade having a first sharp edge aligned in a first direction, and a second blade having a second sharp edge aligned in a second direction, opposite the first direction. The second blade is oriented adjacently in proximity with the first blade so that they may slide closely besides one another. The first sharp edge has a first concavely-curved indent, and the second sharp edge has a second concavely-curved indent aligned opposite the first concavely-curved indent. The first and second concavely-curved indents form an opening between the first sharp edge and the second sharp edge. The opening is adapted to receive a pill for cutting when the first blade is moved in the first direction and the second blade is concurrently moved in the second direction, which effectively splits the pill for precise dosing and reduced waste.

Abstract: A turntable is divided into an inner part (50) and an outer part (40). The angular speed of a large-diameter turntable 40 is made higher than the angular speed of a small-diameter turntable 50, and a tablet transfer path 32 of a straightening guide 30 is configured to be a spiral path extending from an inner end portion 32a to an outer end portion 32b. A tablet contact portion (64) of a tablet holding mechanism is reciprocated with respect to a temporary holding area (62) located before the outer end portion 32b. A tablet is temporarily held in the temporary holding area and when a long narrow blade insertion slit 43 in the large-diameter turntable 40 reaches the temporary holding area, a tablet cutting blade of a tablet cutting mechanism is reciprocated with respect to the temporary holding area and a blade insertion notch (62, 63) to split the tablet.

Abstract: A method for filling a tray with individual medicine portions, which are removed from medicament packs that are provided from an automated storage system by means of an output/input station, is provided. A target filling of accommodating compartments of the tray is provided to a control device, which determines the medicament packs to be removed from storage and the sequence of the removal. For removal, a medicament pack is placed on a first transfer position of the output/input station by an operating device, transported to an output position by a first transport device as soon as the output position is free, and removed from the output position. Individual portions are removed from the medicament pack and introduced into respective accommodating compartments of the tray as indicated by an indicating device. The medicament pack is transported to a second transfer position by a second transport device.

Abstract: A tablet and capsule dispensing assembly, comprising a case including an inner circumferential surface having a first plurality of teeth a tablet disc having a plurality of tablets disposed circumferentially thereon, the tablet disc arranged to rotate within the case, and a lock arranged to engage with the first plurality of teeth to prevent rotation of the tablet disc in a first rotational direction during a first predetermined time interval.

Abstract: A liquid lipstick composition capable of forming a multilayer structure after application to lips, wherein the liquid lipstick composition includes at least two immiscible components prior to application, wherein the at least two immiscible components are: Component A which includes 15% to 60% by weight with respect to the total weight of the composition of at least one film foiiiiing agent having at least one glass transition temperature which is lower than normal human body temperature; and Component B which includes 0.01% to about 80% by weight with respect to the total weight of the composition of one or more silicone compounds in amounts sufficient to achieve a viscosity of 1000 cSt to 900,000 cSt, wherein the weight ratio of film forming agent(s) in Component A to silicone compound(s) in Component B is from 50:1 to 1:2, as well as methods and kits including the liquid lipstick composition.

Abstract: Lipid microcapsules are described that can include at least one irritant active substance, more specifically a retinoid, in a soluble form. Also described, are pharmaceutical compositions comprising the same, and methods for the production thereof. A method of using the composition to treat dermatological pathologies is also described.

Abstract: Zinc oxide compositions and methods for applying anti-reflective coating on oxide particles for sunscreen applications are provided herein. A method includes selecting one or more coating materials to be applied to zinc oxide particles in a sunscreen composition, wherein said selecting is based on optical properties of the coating materials, wherein the optical properties comprises at least the refractive index of each of the coating materials, and applying the selected coating materials to the zinc oxide particles to create the sunscreen composition. A composition includes multiple zinc oxide particles suspended within a medium forming sunscreen composition, and one or more coating materials applied to each of the zinc oxide particles, wherein each of the coating materials has a refractive index that is between the refractive index of air and the refractive index of zinc oxide, and wherein at least one of the coating materials incorporates a textured surface.

Abstract: An oral care composition comprising high water oral care compositions comprising an orally acceptable carrier, zinc phosphate, a first stannous ion source (i.e., stannous fluoride), and a second stannous ion source (i.e., stannous chloride). Methods and uses for this composition are also described throughout.

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same.

Abstract: An aqueous ionic solution based on dissolved mineral salts, in particular intended for throat care, especially for the treatment, prevention and relief of manifestations related to sore throats. The aqueous ionic solution includes: by way of aqueous solvent, at least 20% by weight, with respect to the total weight of the composition, of a hypertonic solution of mineral salts having an osmolality greater than 350 mOsm/kg; at least 50% of one or more polyols of plant origin, by weight with respect to the total weight of the ionic solution; at least one sucrose and C8-C24 fatty acid ester, by weight with respect to the total weight of the ionic solution; and a non-alcoholic extract of propolis and/or between 1% and 8% honey, by weight with respect to the total weight of the ionic solution.

Abstract: Disclosed is a hair care composition comprising: a cationic surfactant system; a high melting point fatty compound; a fatty ester of benzoic acid; a non-volatile hydrocarbon oil; and an aqueous carrier. The compositions of the present invention provide conditioning benefits, especially dry conditioning benefits, while providing improved clean feel.

Abstract: A colchicine-containing composition comprising colchicine as the active ingredient or colchicine in combination with pentoxifylline and tocopherol (Vitamin E) which are formulated for topical use in the prevention and treatment of radiation-induced fibrosis. And methods of making and administering the colchicine-containing compositions. The compositions can be used as topical applications for the prevention and treatment of radiation-induced fibrosis, commonly known as scarring, that can be debilitating, and can occur as a late and permanent complication of radiation therapy.

Abstract: The present invention relates to a composition for reshaping keratin fibers, preferably the hair, having a specific range of a pH and including at least one specific active compound in an amount of 8% by weight or more relative to the total weight of the composition. The composition according to the present invention is preferably a cosmetic composition, for keratin fibers, such as hair, and can be used for a process for reshaping the keratin fibers with heat. The process according to the present invention can be used to deform or reshape keratin fibers, preferably hair, and can provide the keratin fibers with sufficient reshaping efficiency such as strong wave intensity of the curled keratin fibers and excellent hair conditioning effects (less damage to the keratin fibers), in a relatively short period of time as compared to a conventional process which uses a reducing agent and an oxidizing agent.

Abstract: A hair dye composition comprising the following components (A), (B) and (C) and having pH (25° C.) of 7.5 or more and 12 or less: (A): one or more azo dyes selected from the group consisting of the following (A-1), (A-2) and (A-3): (B): a cationic compound (C): 0.1 mass % or more and 8 mass % or less of at least one alkali metal salt of an acid selected from the group consisting of hydrochloric acid, carbonic acid and sulfuric acid.