Abstract: A handheld acoustic shock wave or pressure pulse applicator device has a body structure and an applicator head. The body structure has a proximal end and a distal end with a longitudinal axis extending between the ends. The applicator head is at the distal end. the head emits pressure pulses or shock waves at an inclined angle relative to the longitudinal axis of the body structure. The applicator head has a balloon or lens or membrane through which the emitted pressure pulses or shock waves pass. The lens or membrane is configured to be coupled directly or indirectly to an exposed soft tissue surface of a palate inside a patient's mouth to direct emitted pressure pulses or shock waves to the brain. The applicator device can be configured with the inclined obtuse angle fixed between 150 degrees and 90 degrees or can be adjustable between 180 degrees and 90 degrees.

Abstract: A CPR chest compression machine includes a retention structure that is configured to retain a body of the patient, and a compression mechanism. The compression mechanism is coupled to the retention structure and configured to perform successive compressions to the patient's chest. Various types of chest compressions may be performed on a patient during a single resuscitation event. Some embodiments also include a driver configured to drive the compression mechanism. The compression mechanism may thus perform chest compressions that differ from each other in a number of aspects, for example the depth of the compressions or the height of the active decompressions between the compressions. Some embodiments also include an adjustment mechanism. The adjustment mechanism may shift the compression mechanism with respect to the patient so that the chest compressions are performed at different locations of the patient's chest.

Abstract: The present disclosure provides a cardio pulmonary resuscitation (CPR) apparatus for performing a chest compression on a patient supported by a support. The apparatus includes an actuator operatively coupled to a compression mechanism for actuating the compression mechanism to perform the chest compression. The compression mechanism is securable to the support and is configured to repeatedly perform chest compressions on the patient in an operating space, the operating space being the space in which the compression mechanism operates. The actuator is positioned outside of the operating space. The present disclosure further provides a monitoring system having the CPR apparatus and a feedback system coupled to the CPR apparatus.

Abstract: A soaking chair comprising: a bucket seat comprising a seat back, a seat surface, and two armrests; and a support structure; wherein the chair is suitable for use in a shower; and wherein the seat surface comprises a reservoir and a moveable dam panel near a front end of the seat surface.

Abstract: An objective of the present invention is to provide users a face cradle that form-fits to the unique contours of a user's face, as the user suspends their face within the elastic woven components of the face cradle. Accordingly, the present invention provides an apparatus comprising of a structure that holds a webbed elastic face rest. Preferably, the present invention comprises an arch shaped webbing formed over a rigid structure. According to a preferred embodiment, the present invention is shaped similar to that of a vortex or torus that can stretch, and form fit to the user's head/face with no pressure points. Furthermore, the present invention may exist as a standalone structure, or a removable attachment to a previously existing structure for attaching to a treatment table.

Abstract: The present disclosure relates to a medication delivery system including a medication administration device, a medication within the medication administration device, a container defining a cavity receiving the medication administration device, and a cap attached to the container and sealing the medication administration device within the cavity. The medication administration device includes an actuator extending from a body and operable to expel the medication by depressing the actuator into the body. The cap includes hold down members positioned to bear against the body of the medication administration device to prevent movement of the medication administration device toward the cap beyond a predetermined distance. The medication administration device is thereby prevented, inter alfa, from prematurely discharging the medication during storage and transport.

Abstract: A pre-filled syringe is disclosed, comprising a barrel and a plunger, the barrel having an outlet, the barrel containing a pharmaceutically acceptable solution having a non-physiological pH, wherein the syringe further comprises an ion exchange material. The ion exchange material is provided at a position to allow contact with the pharmaceutically acceptable solution upon ejection of the Pharmaceutically acceptable solution from the barrel via the outlet. The ion exchange material is capable of adjusting the pH of the solution from a non-physiological pH, at which the pharmaceutically acceptable solution is stored in order to ensure acceptable shelf life, to a more physiological pH at which the discomfort and/or pain experienced during injection may be alleviated.

Abstract: The invention relates to a valve unit for a system for producing a parenteral nutrition, in which a three-way valve is used for respectively two connections to a source container. The valve unit is a component which is mounted on the system and can be removed again following use. The valve unit is in particular provided as a replaceable disposable component.

Abstract: A storage container for medication and medical items includes a first section defining a first cavity to receive a first portion of the medication and medical items; a second section defining a second cavity to receive a second portion of the medication and medical items; at least one tray positioned in at least one of the first section and the second section configured to hold the respective medication and medical items; and at least one educational information card positioned in at least one of the first section and the second section. The educational information card includes information pertaining to the medication and how to use the medical items held in the at least one tray.

Abstract: A tubing assembly for use in conjunction with electronic catheter guidance systems is provided and includes a catheter and a sensor. The catheter extends in a longitudinal direction and has a proximal end and a distal end that define a lumen therebetween. Further, the catheter is configured for placement within a digestive tract of a patient. The sensor includes a temperature sensor, relative humidity sensor, or both, and can be located within the lumen of the catheter or in an air sampling chamber connected to the catheter. The sensor can communicate with a processor to deliver temperature and/or relative humidity readings to a display device. A constant temperature or relative humidity profile, or both after a pre-determined amount of time can indicate placement of the catheter in the digestive tract. A catheter guidance system and a method for accurately placing a catheter in the digestive tract are also provided.

Abstract: The present disclosure relates to a labelled root canal filling material. The labelled root canal filling material according to the present disclosure is filled in a root canal to perform root canal treatment, and includes a main body having a shape corresponding to a shape of the root canal to be filled in the root canal and to be removed by a cutting tip after being inserted into the root canal; and a remaining portion integrally formed with the main body, having a mark to be distinguished from the main body, and remaining in the root canal when the main body having inserted into the root canal is removed by the cutting tip.

Abstract: A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.

Abstract: A method of installing a dental prosthetic device includes securing a first guide member to an alveolar arch in a mouth of a patient. The first guide member is utilized to achieve a substantially planar bone surface along the alveolar arch. A second guide member is coupled with the first guide member. The second guide member is utilized to install one or more implants in the alveolar arch through substantially planar bone surface. A dental prosthetic is secured to the one or more implants. The dental prosthetic includes nanoceramic material.

Abstract: The present disclosure concerns a cosmetic composition comprising a film-forming polymer, a cosmetically acceptable solvent capable of dissolving the film-forming polymer, a particulate material and a cosmetically acceptable propellant. The film-forming polymer comprises a PVP/VA co-polymer and the particulate material comprises a hydrophobized fumed silica and/or a modified starch.

Abstract: Described herein is a wet wipe including a substrate and a lotion. The lotion includes from about 95% to about 99.9% water by weight of the lotion and an odor reducing composition comprising a natural extract, wherein the natural extract is selected from one of: magnolia extract, marigold extract, white tea extract, green tea powder, olive oil, green tea extract, white tea powder, and combinations thereof. The lotion has a pH from about 3.6 to about 4.8.

Abstract: The present invention provides a patch for attaching to teeth or a surrounding part of teeth, and the patch can be easily removed by tooth brushing alone.

Abstract: A method for producing a nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method including the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution; mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension; and allowing the obtained suspension to stand still to obtain a transparent composition. Unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.

Abstract: A non-rinse micellar water composition; method of manufacture for a non-rinse micellar water composition; and a method of use for a micellar water composition are disclosed.

Abstract: A solid temporal colorimetric hydrogel cosmetic composition includes 15 to 99.90 wt % of the water phase part and 0.10 to 85 wt % of the oil phase part, having a refractive index difference of 0 to 0.02 therebetween, and having a color change according to variations in a refractive index difference between the water phase part and the oil phase difference when applied to the skin. The cosmetic composition not only has flexibility through irradiation of gamma-rays, but also enables an optimal application time of the cosmetic composition to be visually confirmed through a color change from transparency to ivory white due to a change in the refractive index difference caused by absorbency and volatilization of water when applying the composition to the skin. The cosmetic composition is capable of improving quality of a product although a preservative irritating to the skin is not added.

Abstract: An oil-in-water emulsion cosmetic using an ultramicroemulsion that is excellent in transparency and high in viscosity is provided. The oil-in-water emulsion cosmetic includes: (A) 10 to 50% by mass of an ultramicroemulsion including the following (a1) and (a2): (a1) is an anionic surfactant, and (a2) is a linear higher alcohol having 16 or more carbon atoms that can form an ?-gel in water in combination with (a1); (B) 0.2 to 2% by mass of a stearoxy hydroxypropyl methyl cellulose having the following formula (1); and (C) 0.1 to 1% by mass of a nonionic surfactant.

Abstract: The present invention relates to a stable and clear microemulsion comprising: an oil phase comprising an hydrophobic active ingredient; an aqueous phase; and a surfactant system comprising: a non-ionic primary surfactant system; a first non-ionic co-surfactant system, and a second non-ionic co-surfactant system.

Abstract: Compositions and methods for the styling and temporary hold of keratin are provided. An exemplary composition for the styling and temporary hold of keratin includes a solvent, a polymer, and a propellant having nitrogen. After being dispensed from a compressed container, the composition has an increased density at ambient temperature and pressure as compared to conventional non-nitrogen propelled compositions. Further, such a composition may be free of volatile organic compounds (VOCs).

Abstract: A deodorant composition comprising a magnesium salt and an aqueous carrier, wherein the deodorant composition is substantially free of aluminum.

Abstract: The present invention relates to a method for forming an anhydrous, moldable, cosmetic composition. According to the method, four cosmetic waxes are combined in a vessel to form a first phase. A solvent and wetting agent are combined in a separate vessel to form a second phase. Then, the first and second phases are combined to form a cosmetic composition. The cosmetic composition has a high pigment load while having excellent feel and payoff characteristics.

Abstract: The various aspects presented herein relate to the cooling and flavor boosting compositions, and their use thereof.

Abstract: Oil compositions containing two or more mixtures selected from the group consisting of a lauroyl glutamic acid diester mixture having a melting point higher than 33° C., a lauroyl glutamic acid diester mixture having a melting point of 20 to 32° C., and a lauroyl glutamic acid diester mixture having a melting point of ?20° C. or lower can simultaneously achieve the texture properties (melting smooth feel, uniform spread over the lip surface, and transparent gloss), stability (such as improvement in breaking strength and improvement in temporal stability of the breaking strength), and the elasticity necessary for improving makeup duration of a lipstick.

Abstract: This invention relates to high-water oral care compositions comprising a basic amino acid or salt thereof, together with a precipitated calcium carbonate, glycerol, and to methods of using and of making these compositions.

Abstract: This invention relates to oral care compositions, for example comprising a salt of a basic amino acid having a pH in solution of less than 7.5, an abrasive having a pH in solution of less than 7.5, and a fluoride ion source, and an acid selected from the group consisting of: a carboxylic acid (e.g., citric acid, lactic acid, glycolic acid, acetic acid, succinic acid, or fumaric acid), and an inorganic acid, wherein the inorganic acid is not phosphoric acid or sulfuric acid (e.g.

Abstract: The present invention relates to a process for dyeing keratin fibres, in particular human keratin fibres such as the hair, using one or more particular 2-azo(benz)imidazolium dyes and one or more fluorescent dyes. The present invention also relates to a cosmetic composition comprising the dyes defined above, and also to a multi-compartment device containing said dyes. The present invention also relates to the use of said dyes for dyeing light keratin fibres, especially human keratin fibres such as the hair, in chestnut-brown, dark chestnut-brown, brown, brown with a glint, or even black, without using an additional dye other than those defined above.

Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

Abstract: The present disclosure relates to anhydrous mineral sunscreen cosmetic composition comprising: a) From about 0.1% to about 2% of one silica silylate; b) From about 0.1% to about 5% of allantoin; c) From about 1% to about 12% of one at least one emulsifier; d) From about 0.1 to about 5% of at least one film former; e) From about 1% to about 25% of one or more mineral UV filtering agents; f) From about 20% to about 30% by weight of at least a first silicone having a viscosity from about between 2 cst to about 70 cst; and g) From about 40% to about 95% by weight of at least a second silicone; wherein all weight percentages are based on the total weight of the cosmetic composition.

Abstract: Silk coated and/or infused performance materials and apparel, and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, leather, and other materials that are coated with aqueous solutions of recombinant silk-based protein fragments, such as recombinant spider silk-based protein fragments, having low, medium, and/or high molecular weight in various ratios.

Abstract: A penis nourishing and invigorating cream that nourishes the dermis of a penis and promotes the widening of the arteries and blood vessels of the penis. The cream comprises of a distilled water, at least one antioxidant, at least on thickening agent, at least one preservative, at least one emulsifier, a skin penetrator, a mineral oil, and a nitric oxide generating natural supplement.

Abstract: The present disclosure relates to stable cosmetic compositions for delivering high amounts of ascorbic acid (vitamin C) and ceramides to the skin, products containing such cosmetic compositions, and methods for treating skin using the cosmetic compositions. The cosmetic compositions include ascorbic acid, one or more ceramides, panthenol, one or more monoalcohols having from 2 to 6 carbon atoms, one or more polyols, one or more fatty compounds, one or more emulsifiers, one or more cationic surfactants, and water. The cosmetic compositions are particularly useful for treating the effects of skin aging, for example, reducing the appearance of wrinkles and improving skin tone.

Abstract: A method and system for a multi-layer peelable nail cosmetic compositions are disclosed. The multi-layer system includes a water-washable, non-UV curable nail basecoat composition in a hand-held, non-pressurized container. The basecoat composition includes a hydrophilic poly(N-vinyl)lactam polymer, at least one alcohol, and at least one plasticizer. The multi-layer system also includes a colored non-UV curable nail colorcoat composition that includes a primary film former, a secondary film former, a plasticizer, and a colorant.

Abstract: The present disclosure relates to anhydrous cosmetic compositions comprising: a) From about 0.1% to about 2% of one silica silylate; b) From about 0.1% to about 5% of allantoin; c) From about 0.1% to about 5% of at least one fatty substance; d) From about 2% to about 30% of at least one emulsifier; e) From about 20% to about 30% of at least a first silicone having a viscosity from about between 2 cst to about 70 cst; and f) From about 50% to about 95% of at least a second silicone; wherein all weight percentages are based on the total weight of the cosmetic composition.

Abstract: The present invention relates to an anhydrous, moldable, cosmetic composition comprising a blend of waxes. The wax blend includes at least four distinct waxes, each characterized by having melting temperatures of from about 60° C. to about 65° C.; from about 33° C. to about 46° C.; from about 88° C. to about 96° C.; and from about 74° C. to about 99° C., respectively. The compositions further include at least one solvent, and a high pigment load. The compositions have excellent feel and payoff characteristics.

Abstract: A kit includes primer composition includes a vehicle comprising water and one or more first film-forming polymers stabilized in the vehicle, wherein the first film-forming polymer that is a non-ionic and water-soluble or water dispersible copolymer comprising a cyclic amide monomer, a cyclic amine monomer, and an acrylamide monomer. It further includes a mascara composition including water; colorant; wax; emulsifier; and one or more second polymers. The mascara composition has a critical shear rate from 2.5/s to 100/s. Methods of applying makeup to the eyelashes are also provided.

Abstract: A two-phase cosmetic composition includes an anhydrous phase and an aqueous phase in which the anhydrous and aqueous phases are separated by a single-phase interface. The anhydrous phase includes a plurality of fatty compounds and at least one thickener where the plurality of fatty compounds is present at about 30% by weight, based on the total weight of the composition, and the aqueous phase includes an acetic acid component.

Abstract: Disclosed are personal care formulations for delivery to the skin of a person in the form of an aerosol comprising: (1) non-propellant components comprising at least one active ingredient in the form of finely divided particles, at least one hydrophobized clay, a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier wherein: (i) the weight ratio of said trans-1233zd:co-carrier is from about 0.25:1 to about 4:1; (ii) said trans-1233zd and said co-carrier together comprise at least about 40% by weight of said hydrophobic carrier.

Abstract: The invention concerns dermatological or cosmetic compositions having a depigmenting action by topical application and comprising at least an effective amount of the specific combination of six constituents. It also concerns the use of an effective amount of said specific combination of six constituents acting in combination on melanogenesis as active compounds for the preparation of a dermatological composition intended for treating pathological or accidental hyperpigmentation. Finally, it concerns a cosmetic treatment method intended to improve the aesthetic appearance of the skin, consisting of applying a sufficient amount of a composition according to the invention to the skin.

Abstract: Breath freshening formulations comprising licorice extract and menthol are provided. The breath freshening formulations can provide breath freshening in a confectionary product, through the synergy between licorice extract and menthol. Methods of reducing sulfurous compounds over time via a chewy confectionary product are also provided.

Abstract: The present invention relates to the use of gingival fibroblast-derived products to reduce hair loss and promote hair growth. Specifically, the invention relates to a product derived from gingival fibroblasts to be used in the treatment or prevention of alopecia, as well as in the promotion of natural hair growth and/or in the control of natural hair loss.

Abstract: Disclosed is a topical skin care formulation comprising water, kaolin, glycerin, lactobacillus ferment, Helianthus annuus seed extract, and Terminalia ferdinandiana fruit extract.

Abstract: Disclosed is an osmotic pump controlled release formulation, comprising a core and a membrane, wherein the membrane is coated on an outer surface of the core, the formulation has at least one channel, the core is communicated with to the outer surface of the formulation via the channel, lateral length of the channel is 1.40 mm-2.50 mm, and depth of the channel is 2.05 mm-2.95 mm.

Abstract: Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

Abstract: Methods and compositions for treating a patient for a condition characterized by an excess blood concentration of dissolved gas in at least one targeted region of the patient are provided. The method comprises administering a composition comprising a perfluorocarbon droplet emulsion into the blood of the patient; insonifying the at least one target region sufficient to achieve formation of microbubbles by droplet vaporization of at least a portion of the perfluorocarbon droplets present in the blood; whereby a concentration gradient favoring movement of gas molecules from the blood into the microbubbles is established for a time frame.

Abstract: The invention relates to pharmacology and to a composition for making an antitumor agent in the form of a solution for injection. The composition contains alloferon at a concentration of 0.05 to 0.1% wt, cis-diamminedichloridoplatinum at a concentration of 0.01 to 0.05% wt, and water. The composition of the present invention features antitumor activity and hypotoxicity. 1 Figure, 3 Tables, 5 examples.

Abstract: The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases.

Abstract: A medical device comprising a composition comprising a therapeutically active amount of active agent, a zinc compound, and an array of microneedles. The zinc compound may be selected from the group consisting of zinc, pharmaceutically acceptable salts of zinc, and mixtures thereof. At least a portion of the composition is present as a coating on at least a portion of the microneedles. Methods of delivering a therapeutically active agent to a mammal using compositions of the disclosure are also included.