Patents Issued in December 31, 2020
  • Publication number: 20200406227
    Abstract: A carbon skeleton reinforced porous starch and a preparation method thereof. The method of preparing the porous starch includes bonding starch to transition metal ions, then treating the starch attached with the transition metal ions and amylase via an extruding device, and finally forming a starch-based porous material having a high strength recombination structure, that is, the carbon skeleton reinforced porous starch.
    Type: Application
    Filed: July 11, 2018
    Publication date: December 31, 2020
    Applicant: Jiangnan University
    Inventors: Zhengyu JIN, Enbo XU, Zhengzong WU, Aiquan JIAO, Xing ZHOU, Yaoqi TIAN, Jinpeng WANG, Yuxiang BAI, Jianwei ZHAO, Zhengjun XIE, Xueming XU, Na YANG
  • Publication number: 20200406228
    Abstract: The method for preparing a super absorbent polymer according to the present disclosure reduces the generating amount of a fine powder while realizing the same particle size distribution in the process of pulverizing the dried polymer, thereby reducing the load of the fine powder reassembly, drying, pulverizing and classifying steps.
    Type: Application
    Filed: August 16, 2019
    Publication date: December 31, 2020
    Applicant: LG Chem, Ltd.
    Inventors: Yoon Jae Min, Jong Hun Song, Gicheul Kim, Jae Yul Kim, Heechang Woo
  • Publication number: 20200406229
    Abstract: A chromatography column for the use of separation of acidic sugar chains, wherein the column comprises a first column and a second column, the second column connected by a flow path downstream of an outlet of the first column, and selected from the following (1) or (2): (1) the carrier of the first column is hydrophobically modified silica having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine; (2) the carrier of the first column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is hydrophobically modified silica having a group containing a primary amine, a secondary amine, or/and a tertiary amine.
    Type: Application
    Filed: November 14, 2018
    Publication date: December 31, 2020
    Applicant: JCR Pharmaceuticals Co., Ltd.
    Inventors: Tomoki FUKATSU, Chika MOROOKA
  • Publication number: 20200406230
    Abstract: A protein-binding product comprising one or more porous polymer beads, wherein at least one ligand is bound to the surfaces of said polymer beads via a spacer (R), and wherein said at least one ligand is Gal?1-3HexNAc?—O—, Gal?1-4GlcNAc?—O— and/or a derivative thereof, is disclosed as well as a device containing said protein-binding product and a method for reduction of the level of at least one galactose-binding protein and optionally at least one other protein in human blood plasma.
    Type: Application
    Filed: March 8, 2019
    Publication date: December 31, 2020
    Applicant: GLYCOREX TRANSPLANTATION AB
    Inventor: Kurt NILSSON
  • Publication number: 20200406231
    Abstract: A method of separating biomolecules in an aqueous mixture is disclosed comprising a obtaining a separation vessel containing separation media, wherein the separation media comprises a porous support with a hydrophobic monomer grafted thereon, the hydrophobic monomer having the structure: CH2?CR4C(O)NHC(R1R1)(C(R1R1))nC(O)XR3 wherein n is an integer of 0 or 1; R1 is independently selected from at least one of: a hydrogen atom, alkyls, aryls, and alkylaryls, wherein the alkyls, aryls, and alkylaryls have a total of 10 carbon atoms or less; R3 is a hydrophobic group selected from at least one of alkyls, aryls, alkylaryls and ethers, wherein the alkyls, aryls, alkylaryls and ethers have a total number of carbon atoms ranging from 4 to 30; R4 is H or CH3; and X is O or NH; wherein the hydrophobic monomer is derived from an amine or an alcohol (HXR3) that has a hydrophilicity index of 25 or less; and (b) passing the aqueous mixture through the separation vessel thereby separating the biomolecules.
    Type: Application
    Filed: September 14, 2020
    Publication date: December 31, 2020
    Inventors: Jerald K. Rasmussen, Cary A. Kipke, Peter D. Wickert
  • Publication number: 20200406232
    Abstract: Chromatography resins having anionic exchange-hydrophobic mixed mode ligands, that are useful for purifying target biomolecules using anionic exchange (i.e., where the ligand is positively charged) and hydrophobic mixed mode chromatography. The chromatography resins allow for efficient purification of target biomolecules (e.g., recombinant proteins, antibodies, antibody-drug conjugates, or antibody derivatives including, but not limited to, antibody fragments and antibody fusions) from a sample, and have been found to be useful in purifying monomeric target biomolecules from aggregate target biomolecules. In an embodiment, the chromatography resins are useful for separating antibodies from one or more components (e.g., contaminants) in the sample.
    Type: Application
    Filed: March 8, 2019
    Publication date: December 31, 2020
    Inventors: CHRISTOPHER BELISLE, HONG CHEN, YUEPING XU, JIALI LIAO, XUEMEI HE
  • Publication number: 20200406233
    Abstract: The present invention discloses a bismuth oxide (Bi2O3)/bismuth subcarbonate ((BiO)2CO3)/bismuth molybdate (Bi2MoO6) composite photocatalyst, including a Bi2MoO6 photocatalyst, where Bi2O3 and (BiO)2CO3 nanosheets are introduced to a surface of the Bi2MoO6 through addition of Na2CO3 and roasting. The present invention also discloses a preparation method of the Bi2O3/(BiO)2CO3/Bi2MoO6 composite photocatalyst which is specifically implemented by the following steps: step 1: preparing a Bi2MoO6 photocatalyst; step 2: introducing Bi2O3 and (BiO)2CO3 nanosheets to a surface of the Bi2MoO6 photocatalyst obtained in step 1 through addition of Na2CO3 and roasting to obtain the Bi2O3/(BiO)2CO3/Bi2MoO6 composite photocatalyst. The photocatalyst of the present invention has no agglomeration, a wide responsive range of visible light, a significantly improved catalytic activity compared with a Bi2MoO6 alone, and excellent reusability.
    Type: Application
    Filed: June 24, 2020
    Publication date: December 31, 2020
    Applicant: YAN'AN UNIVERSITY
    Inventors: Feng FU, Huidong SHEN, Danjun WANG, Yanzhong ZHEN, Wenwen XUE, Long YAN
  • Publication number: 20200406234
    Abstract: A catalyst for gasoline engine exhaust gas after-treatment, comprising Pt and optionally at least one other platinum group metal on a hydrothermal stable support material which is coated onto a gasoline particulate filter. The catalyst oxidizes particulate matter trapped in the gasoline particulate filter under low temperature and abates NOx, CO and HC. Also a process for preparing the catalyst is disclosed, and a method for after-treatment of gasoline engine exhaust gas using the catalyst is disclosed.
    Type: Application
    Filed: February 22, 2019
    Publication date: December 31, 2020
    Applicant: BASF Corporation
    Inventors: Yun Fei QI, Jun Cong JIANG, Shau Lin CHEN, Weiyong TANG, Yu Lin QIU, Liang Fang LV, Yan Zhu LEI
  • Publication number: 20200406235
    Abstract: Provided herein is a method of preparing a porous composite ceramic material and a porous composite ceramic material made by the method of preparing.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 31, 2020
    Inventors: Diana Berman, Elena Shevchenko, Matteo Cargnello, Benjamin Diroll, Emmett Goodman
  • Publication number: 20200406236
    Abstract: A catalyst for decomposing an organic substance, the catalyst having a body which has a plurality of pores and the body contains a perovskite-type composite oxide represented by AxByMzOw, where the A contains at least one selected from Ba and Sr, the B contains Zr, the M is at least one selected from Mn, Co, Ni, and Fe, 1.001?x?1.1, 0.05?z?0.2, y+z=1, and w is a positive value that satisfies electrical neutrality. The average pore diameter of the plurality of pores is 49 nm to 260 nm and the pore volume of each of the plurality of pores is 0.08 cm3/g to 0.37 cm3/g.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: Kentaro Ishihara, Nario Sugahara, Satoshi Kuretake, Naoya Mori, Hideto Sato
  • Publication number: 20200406237
    Abstract: The invention relates to a process for the production of ethylene glycol including the steps of: (i) reacting, in a reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C., at least a portion of a carbohydrate source in the presence of hydrogen, a solvent, a homogeneous catalyst, which homogeneous catalyst contains tungsten, and a heterogeneous catalyst, which heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements, yielding ethylene glycol and a spent heterogeneous catalyst; (ii) regenerating the spent heterogeneous catalyst by removing at least a portion of deposited tungsten species from the spent heterogeneous catalyst, yielding a regenerated heterogeneous catalyst; and (iii) using at least a portion of the regenerated heterogeneous catalyst as heterogeneous catalyst in the reaction of step (i).
    Type: Application
    Filed: March 14, 2019
    Publication date: December 31, 2020
    Inventors: Jagdeep Singh, Paula Dekker, Jan Cornelis Van Der Waal, Benjamin McKay
  • Publication number: 20200406238
    Abstract: The invention relates to a catalyst comprising a support, at least one noble metal M, tin, phosphorus and yttrium, the content of phosphorus element being less than or equal to 1% by weight, and the content of yttrium being less than or equal to 1% by weight relative to the mass of the catalyst. The invention also relates to the process for preparing the catalyst and to the use thereof in reforming.
    Type: Application
    Filed: November 16, 2018
    Publication date: December 31, 2020
    Applicant: IFP Energies Nouvelles
    Inventors: Fabrice DIEHL, Carine GUEGAN
  • Publication number: 20200406239
    Abstract: A cobalt carbide-based catalyst for direct production of olefin from synthesis gas, a preparation method therefor and application thereof are disclosed. The method for preparing the catalyst comprises the following steps: 1) mixing a cobalt source with water, or mixing a cobalt source, an electron promoter and water to obtain a first solution; and mixing a precipitant with water to obtain a second solution; 2) adding the first solution and the second solution to water, or water and a structure promoter for precipitation, crystallizing, separating, drying and calcination; and 3) reducing a solid obtained in Step 2) in a reducing atmosphere, and then carbonizing in a carbonizing atmosphere. The prepared catalyst has high activity and high selectivity to olefins for direct production of olefins via syngas conversion.
    Type: Application
    Filed: September 29, 2016
    Publication date: December 31, 2020
    Applicants: SHANGHAI ADVANCED RESEARCH INSTITUTE, CHINESE ACADEMY OF SCIENCES, SHANXI LUAN ENVIRONMENTAL ENERGY DEVELOPMENT CO., LTD.
    Inventors: ZHENGJIA LI, LIANGSHU ZHONG, YUHAN SUN, FEI YU, YUNLEI AN, XINGZHEN QI, TIEJUN LIN, YANING XIAO, BIN LIU, DONGFEI WANG
  • Publication number: 20200406240
    Abstract: The present invention provides lanthanide-supported transition metal catalysts synthesized using high-nitrogen energetic precursors; processes for the preparation of said catalysts and for coating inert ceramic monoliths with said catalysts; and uses thereof, e.g., in reforming of methane.
    Type: Application
    Filed: June 14, 2018
    Publication date: December 31, 2020
    Inventors: Brian Ashley Rosen, Michael Gozin, Moran Dahan, Eswara Vara Prasadarao Komarala, Ludmila Fadeev, Ajay Kumar Chinnam, Avital Shlomovich
  • Publication number: 20200406241
    Abstract: An object of the invention is to provide an oxygen reduction catalyst composed of a titanium oxynitride having high oxygen reduction capacity. The oxygen reduction catalyst of the invention is a titanium oxynitride that has a nitrogen element content of 0.1 to 2.0 mass %, has a crystal structure of rutile titanium dioxide in a powder X-ray diffraction measurement, and has a signal intensity ratio N—Ti—N/O—Ti—N in an X-ray photoelectron spectroscopic analysis of in the range of 0.01 to 0.50. Further, the oxygen reduction catalyst of the invention is a titanium oxynitride that includes titanium oxide particles, has a crystal structure of rutile titanium dioxide, and has an amorphous layer in a surface layer of the titanium oxide particles.
    Type: Application
    Filed: December 22, 2017
    Publication date: December 31, 2020
    Applicants: SHOWA DENKO K.K., NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY
    Inventors: Kunchan LEE, Yoshinori YAMATO, Kenichiro OTA, Akimitsu ISHIHARA
  • Publication number: 20200406242
    Abstract: A catalyst, which comprises molecular sieves; a molecular sieve structure is at least provided with a one-dimension eight-membered annular small hole channel, wherein the diameter of a substance that may diffuse in the direction of the eight-membered annular channel is no less than 2.0 ?, and the diameter of a substance that may be accommodated in the molecular sieves is no more than 6 ?. The catalyst is used for a methanol- and/or dimethyl ether-to-propylene reaction, comprising causing methanol and/or dimethyl ether to make contact with a methanol-to-propylene catalyst to obtain propylene.
    Type: Application
    Filed: December 20, 2017
    Publication date: December 31, 2020
    Applicant: Dallan Institute of Chemical Physics, Chinese Academy of Sciences
    Inventors: Miao YANG, Peng TIAN, Zhongmin LIU, Bing LI, Lin LIU, Shiyun SANG
  • Publication number: 20200406243
    Abstract: The present invention relates to a bifunctional chiral organocatalytic compound having excellent enantioselectivity, a preparation method therefor, and a method for producing a non-natural gamma amino acid from a nitro compound by using the chiral organocatalytic compound. According to the present invention, the bifunctional chiral organocatalytic compound having excellent enantioselectivity can be easily synthesized, gamma-amino acids with high optical selectivity can be obtained at a high yield by an economical and convenient method using the chiral organocatalytic compound, and various (R)-configuration gamma-amino acids, which are not present in nature, can be produced with high optical purity in large quantities by using a small amount of a catalyst, and therefore, the present invention can be widely utilized in various industrial fields including the pharmaceutical industry.
    Type: Application
    Filed: January 24, 2019
    Publication date: December 31, 2020
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Deok-Chan HA, Jae Ho SHIM
  • Publication number: 20200406244
    Abstract: A catalyst including: a first layer including a transition metal; a base layer; and an interlayer, wherein the interlayer is disposed between the base layer and the first layer is disclosed. Also disclosed are methods for preparing a catalyst as well as for synthesizing graphene, a pellicle produced using the catalyst or methods disclosed herein, as well as a lithography apparatus including such a pellicle.
    Type: Application
    Filed: February 7, 2019
    Publication date: December 31, 2020
    Applicant: ASML NETHERLANDS B.V.
    Inventors: Evgenia KURGANOVA, Adrianus Johannes Maria GIESBERS, Alexander Ludwig KLEIN, Maxim Aleksandrovich NASALEVICH, Arnoud Willem NOTENBOOM, Mária PÉTER, Pieter-Jan VAN ZWOL, David Ferdinand VLES, Sten VOLLEBREGT, Willem-Pieter VOORTHUIJZEN
  • Publication number: 20200406245
    Abstract: A honeycomb-structured catalyst for decomposing an organic substance, which includes a catalyst particle. The catalyst particle contains a perovskite-type composite oxide represented by AxByMzOw, where the A contains at least of Ba and Sr, the B contains Zr, the M is at least one of Mn, Co, Ni, and Fe, y+z=1, 1.001?x?1.05, 0.05?z?0.2, and w is a positive value that satisfies electrical neutrality. The toluene decomposition rate is greater than 90% when toluene is decomposed using the honeycomb-structured catalyst subjected to a heat treatment at 1200° C. for 48 hours and a gas that contains 50 ppm toluene, 80% nitrogen, and 20% oxygen as a volume concentration as a target at a space velocity of 30,000/h and a catalyst temperature of 400° C.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: Naoya Mori, Satoshi Kuretake, Nario Sugahara, Kentaro Ishihara
  • Publication number: 20200406246
    Abstract: The invention relates to a method for producing catalysts by the method of combustion in solution, to the catalysts produced by said method, and to the particular use thereof in the reverse water-gas shift reaction and in the partial oxidation of the methane into synthesis gas. Therefore, it is understood that the present invention pertains to the area of the green industry aimed at the reduction of CO2 on the planet.
    Type: Application
    Filed: December 28, 2017
    Publication date: December 31, 2020
    Inventors: María Consuelo ÁLVAREZ GALVÁN, Martín DAPENA OSPINA, José Antonio ALONSO ALONSO, Loreto TRONCOSO AGUILERA, Vanesa CASCOS JIMÉNEZ, José Miguel CAMPOS MARTÍN, José Luis GARCÍA FIERRO, Horacio FALCÓN RICHENI
  • Publication number: 20200406247
    Abstract: The present invention comprises a method for the generation of 227Th of pharmaceutically tolerable purity comprising i) preparing a generator mixture comprising 227Ac, 227Th and 223Ra; ii) loading said generator mixture onto a strong base anion exchange resin; iii) eluting a mixture of said 223Ra and 227Ac from said strong base anion exchange resin using a first mineral acid in an aqueous solution; iv) eluting 227Th from said strong base anion exchange resin using a second mineral acid in an aqueous solution whereby to generate a first 227Th solution containing contaminant 223Ra and 227Ac; v) loading the first 227Th solution onto a strong acid cation exchange resin; vi) eluting at least a part of the contaminant 223Ra and 227Ac from said strong acid cation exchange resin using a third mineral acid in aqueous solution; and vii) eluting the 227Th from said strong acid cation exchange resin using a first aqueous buffer solution to provide a second 227Th solution.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 31, 2020
    Applicant: Bayer AS
    Inventors: Dimitrios MANTZILAS, Jan Roger KARLSON, Judit Tjelmeland ØSTBY
  • Publication number: 20200406248
    Abstract: An ultra-thin anion exchange membrane incorporates functional additives to provide improved water management. Without the functional additives the ultra-thin membrane may have high cross-over and not be effective for many applications. A composite anion exchange membrane includes a porous scaffold support such as a porous polymer. The anion exchange polymer may be coupled to the porous scaffold, such as by being imbibed into the pores of the porous scaffold. The functional additives may contribute to increase water production, water retention, back-diffusion and reduce the gas crossover. A functional additive may include a reactive species, including a catalyst that reacts with oxygen or hydrogen, a plasticizer, a hygroscopic material and/or a radical scavenger.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 31, 2020
    Inventors: Bamdad Bahar, Taoli Gu
  • Publication number: 20200406249
    Abstract: A pipette based on surface charges includes a pipette body. A plurality of support rods are provided below the pipette body. Connecting rods are provided at the lower ends of two adjacent support rods. A substrate is provided between the connecting rods. A porous SiO2 coating is provided on the substrate. A hydrophobic molecule layer is provided on the surface coating by the vapor deposition method. A superamphiphobic surface is formed on the substrate by the surface coating and the hydrophobic molecule layer. The substrate and the surface coating are made of dielectric materials. A circular limit plate is provided above the pipette body. The pipette body, the support rods, the connecting rods and the limit plate are integrally formed, and are electrically non-conductive. An electrically conductive sliding rod is movably provided within the pipette body and the limit plate.
    Type: Application
    Filed: September 19, 2019
    Publication date: December 31, 2020
    Applicant: University of Electronic Science and Technology of China
    Inventors: Xu DENG, Qiangqiang SUN, Yu ZHOU
  • Publication number: 20200406250
    Abstract: The invention is concerned with improvements in the technical field of pipettes. For this purpose, a pipette (1) with a base body (2) and a handle (3) is proposed, wherein a thermal insulation (5) is formed or arranged between the handle (3) and the base body (2) of the pipette (1) (see FIG. 1).
    Type: Application
    Filed: March 9, 2018
    Publication date: December 31, 2020
    Inventor: Philip Döbele
  • Publication number: 20200406251
    Abstract: The present invention is directed generally to devices and methods for manipulating laboratory pipettes in a programmable manner. The present invention is directed to an apparatus and methods for allowing a user to instruct the device to perform a specific process; identifying the type, location and identity of the consumables to be used; manipulating a plurality of pipettes for performing the liquid handling; monitoring the process during and after its execution; generating a detailed report for the plurality of actions. Other aspects of this invention include optimization of the liquid dispensing performances of a pipette; monitoring and controlling individual actions by means of vision; virtualization of the protocol definition by means of a reality augmented software interface; integration of the system in a conventional laboratory environment workflow.
    Type: Application
    Filed: August 6, 2020
    Publication date: December 31, 2020
    Inventors: Piero Zucchelli, Giorgio Horak, Antoine Jordan
  • Publication number: 20200406252
    Abstract: A sample preparation device is provided for enriching a component of a sample. The sample preparation device includes a surface in fluid communication with the sample, an alkylsilyl coating disposed on the surface, and an affinity ligand or an enzyme covalently bonded to the alkylsilyl coating.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 31, 2020
    Applicant: Waters Technologies Corporation
    Inventors: Matthew A. Lauber, Mathew H. DeLano, Beatrice Muriithi, Xiaoxiao Liu, Anna Boardman
  • Publication number: 20200406253
    Abstract: An integrated technological platform enabling real-time quantitative multiparameter metabolic profiling, utilizing either or both of extra and intracellular optical sensors, individually or simultaneously. A scalable embedded micropocket array structure, generally fabricated on fused silica substrates, facilitates the integration of multiple, spatially separated extracellular sensors for multiparameter analysis in a container formed with the use of an activation mechanism forming part of a device configured to hold the container during the measurements. The creation of hermetically sealed microchambers is carried out with a pneumatically and/or mechanically and/or electromechanically driven device that is “floating” within the holding device and that is optionally equipped with a vacuum/suction mechanism to hold a component of the container at its surface.
    Type: Application
    Filed: February 26, 2018
    Publication date: December 31, 2020
    Inventors: Deirdre MELDRUM, Laimonas KELBAUSKAS, Yanqing TIAN, Honor GLENN, Clifford ANDERSON, Kristen LEE, Ganquan SONG, Liqiang ZHANG, Jeff HOUKAL, Fengyu SU, Benjamin UEBERROTH, Jacob MESSNER, Hong WANG, Kimberly BUSSEY
  • Publication number: 20200406254
    Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, devices and methods of performing a biological and chemical extraction from a liquid, and performing assays, such as but not limited to immunoassays and nucleic acid assays.
    Type: Application
    Filed: February 13, 2018
    Publication date: December 31, 2020
    Applicant: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang, Ji Qi
  • Publication number: 20200406255
    Abstract: A microfluidic device, a diagnostic device including the microfluidic device and a method for making the microfluidic device are provided. The microfluidic device includes: (i) a transparent substrate comprising a cavity, the cavity opening up to a top of the transparent substrate; (ii) a transparent layer covering the cavity, and (iii) a semiconductor substrate over the transparent layer and the transparent substrate, wherein the semiconductor substrate comprises a through hole overlaying the cavity and exposing the transparent layer.
    Type: Application
    Filed: May 21, 2020
    Publication date: December 31, 2020
    Inventors: Giuseppe Fiorentino, Simone Severi, Aurelie Humbert
  • Publication number: 20200406256
    Abstract: A hand-held molecular diagnostic test device includes a housing, an amplification (or PCR) module, and a detection module. The amplification module is configured to receive an input sample, and defines a reaction volume. The amplification module includes a heater such that the amplification module can perform a polymerase chain reaction (PCR) on the input sample. The detection module is configured to receive an output from the amplification module and a reagent formulated to produce a signal that indicates a presence of a target amplicon within the input sample. The amplification module and the detection module are integrated within the housing.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Keith E. MORAVICK, Brian CIOPYK, Victor BRIONES, Gregory LONEY, Adam DE LA ZERDA, Jesus CHING, Steven CHU, David SWENSON, Helen HUANG, Colin KELLY
  • Publication number: 20200406257
    Abstract: A method includes conveying a detection solution containing a target amplicon into a detection module of a molecular diagnostic test device. The detection module includes a detection surface including a series of capture probes to which a first portion of the target amplicon is bound when the detection solution is conveyed. A first reagent formulated to produce a visible signal indicating a presence of the target amplicon is then conveyed into the detection module. The first reagent is bound to a second portion of the target amplicon when the first reagent is conveyed. A second reagent is conveyed into the detection module. The second reagent includes a precipitating substrate formulated to catalyze the production of the visible signal by producing an insoluble colored product when the second reagent is in contact with the first reagent. The method includes viewing the visible signal via a transparent portion of the detection module.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: Visby Medical, Inc.
    Inventors: Boris ANDREYEV, Rajinder K. BHATIA, Victor BRIONES, Phoebe CAO, Jesus CHING, Brian CIOPYK, Adam DE LA ZERDA, Jonathan H. HONG, Helen HUANG, Colin KELLY, Adrienne C. LAM, Gregory C. LONEY, Danielle MCSHEERY, Keith E. MORAVICK, Valeria REVILLA, Shaunak ROY, David D. SWENSON
  • Publication number: 20200406258
    Abstract: The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a microfluidic channel. A vent chamber can be in fluid communication with the microfluidic channel. A capillary break can be located between the microfluidic channel and the vent chamber. The capillary break can include a tapered portion and a narrowed opening with a smaller width than a width of the microfluidic channel. A vent port can vent gas from the vent chamber. The vent port can be located a distance away from the capillary break so that a fluid in the capillary break does not escape through the vent port.
    Type: Application
    Filed: April 7, 2017
    Publication date: December 31, 2020
    Applicant: Hewlett-Packand Development Company, L.P.
    Inventors: Alexander Govyadinov, Adam HIGGINS, Pavel KORNILOVICH
  • Publication number: 20200406259
    Abstract: Diagnostic systems for sensing biological molecules are disclosed. The diagnostic systems include a fluid control delivery and control system that can be coupled to a diagnostic cartridge that includes a microfluidic device and integrated sensing electronics. The diagnostic systems can be used to sequence biological molecules.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Inventors: ALBERT CHUEH, STEPHEN F. DREYER, PRIYANKA AGRAWAL, IGOR IVANOV, HUI TIAN
  • Publication number: 20200406260
    Abstract: A method of sample preparation for streamlined multi-step assays is provided. The method includes the step of providing a microfluidic device including a reservoir defined by a surface configured to repel an aqueous solution. A dried reagent is provided on a portion of the surface and the reservoir is filled with an oil. A first droplet formed from the aqueous solution is positioned on the dried reagent so to pick-up and re-dissolve the dried reagent therein so as to expose the portion of the surface. In addition, a second droplet of an aqueous solution may be deposited on a hydrophilic spot patterned on the surface. A magnetic force may be configured to interact magnetically with the paramagnetic beads within the first droplet to move the droplet through the oil in the reservoir or to move the paramagnetic beads from the first droplet, through the oil, into the second droplet.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 31, 2020
    Inventors: David J. Beebe, Joshua M. Lang, Duane S. Juang, Scott M. Berry, Tamara S. Rodems
  • Publication number: 20200406261
    Abstract: Devices, systems, and their methods of use, for generating droplets are provided. One or more geometric parameters of a microfluidic channel can be selected to generate droplets of a desired and predictable droplet size.
    Type: Application
    Filed: June 29, 2020
    Publication date: December 31, 2020
    Inventors: Alireza SALMANZADEH, Rajiv BHARADWAJ
  • Publication number: 20200406262
    Abstract: A method for aliquoting a sample liquid using a sealing liquid in a microfluidic device includes combining the sample liquid and the sealing liquid, which have different wetting behaviors, to form a two-phase system separated by a boundary surface. The microfluidic device includes a chamber with at least one inlet channel for introducing the liquids and a plurality of cavities configured to be filled via the inlet channel. The inlet channel and the cavities have a geometry that is defined in dependence on the respective wetting behaviors of the sample liquid and the sealing liquid. The method first includes introducing the sample liquid to form a first meniscus configured by the defined geometry, e.g. concave, to fill the cavities. The method further includes introducing the sealing liquid to form a second meniscus configured by the existing, greater contact angle and the defined geometry, e.g. convex, to cover the filled cavities.
    Type: Application
    Filed: March 25, 2019
    Publication date: December 31, 2020
    Inventor: Daniel Sebastian Podbiel
  • Publication number: 20200406263
    Abstract: The microfluidic chip includes; at least one inlet channel connected to at least one well, each well being associated with an outlet channel, at least one analysis chamber connected to at least one well, an analysis surface including collection elements capturing biomarkers present in the liquid originating from the well and representative of the cellular response of a biological sample contained in the well. A liquid flow circulates from the well to the analysis surface including the collection elements. The liquid flowrate is between 0.1 ?L/min and 2 mL/min and flows in laminar manner in the analysis chamber. The chip forms part of a microfluidic lab-on-chip provided with a flow generator applying several different liquids.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 31, 2020
    Applicant: NANOBIOSE
    Inventors: Sarah MILGRAM, Damien FLEURY
  • Publication number: 20200406264
    Abstract: A reagent container according to an embodiment is used in an automatic analyzing system configured to measure a liquid mixture of a tested specimen and a reagent. The reagent container includes a case, a bag, and an outlet. The case is stored in a reagent storage. The bag is built in the case, is more flexible than the case, and is configured to contain the reagent. The reagent is taken out through the outlet.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 31, 2020
    Applicant: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Hirotoshi TAHARA, Shin IIDA, Shozo HASHIMOTO
  • Publication number: 20200406265
    Abstract: A carrier for consumables which are mainly used in laboratory (analytic) applications and provides a carrier for consumables, comprising a ground plate with at least two cut-outs for accommodating a consumable, a clamp plate with at least one clamp extending partially above the cut-outs and a locking lever movably connected with the clamp plate, wherein the locking lever has at least a cam located at an end connected with the clamp plate, wherein the cam presses in a locking position of the locking lever the clamp plate towards the ground plate and releases in a releasing position a gap between ground plate and clamp plate.
    Type: Application
    Filed: June 8, 2020
    Publication date: December 31, 2020
    Inventor: Andreas Meyer
  • Publication number: 20200406266
    Abstract: An automatic grinder and a grinding method thereof. The grinder includes a control structure and at least one material container assembly. The control structure includes a driving assembly and a connecting structure connected thereto. The material container assembly includes a material container body (20), a grinding head (22) fixedly connected to the material container body (20), and a grinding sleeve (25) rotatably connected to the grinding head (22). A recess (201) is provided on the material container body (20), engaged with the connecting structure. The grinding head (22) is fitted into the grinding sleeve (25), defining therebetween a material compartment (40) for accommodating a material. The driving assembly drives the material container body (20) to rotate. The material container body (20) drives the grinding head (22) to rotate. The grinding head (22) moves relative to the grinding sleeve (25), such that the material therebetween is ground into powder.
    Type: Application
    Filed: November 12, 2018
    Publication date: December 31, 2020
    Inventors: Alex Liu, Hongjin Liu
  • Publication number: 20200406267
    Abstract: A stirrer mill for the treatment of flowable grinding stock. The stirrer mill includes a milling container, a milling chamber delimited by the container wall, and a stirring mechanism having a rotor which rotates about a central longitudinal axis and has an inside diameter (d351). Tools, which extend toward the container wall, are attached to the rotor. The stirrer mill also includes an internal stator arranged inside the rotor. A grinding stock discharge channel is formed, between the rotor and the internal stator, through which the grinding stock passes to a separating device and, thereafter, to a discharge line. The milling chamber is at least partially filled with grinding bodies having a diameter (c). Above the internal stator is arranged a separating device with a diameter (d30). The distance (s) between the rotor and the grinding body separating device is given by the relationship: s=0.5·(d351?d30)?5·c.
    Type: Application
    Filed: March 5, 2019
    Publication date: December 31, 2020
    Inventors: Eduard NATER, Andreas RIECHE, Norbert KERN, Achim STURM
  • Publication number: 20200406268
    Abstract: Methods and systems for reducing an average particle size of blackwater solids is disclosed. A vessel is configured to receive a blackwater stream through a one-way inlet. The one-way inlet is configured to allow the blackwater stream into the vessel and prevent backflow. The blackwater stream contains blackwater solids and water. A device in a bottom portion of the vessel is configured to receive the blackwater and comminute the blackwater solids. A recirculating pump is configured to recirculate the blackwater stream under pressure through the device until the average particle size of the blackwater solids is reduced below a size threshold, resulting in a sized blackwater stream.
    Type: Application
    Filed: June 28, 2019
    Publication date: December 31, 2020
    Applicant: Hall Labs LLC
    Inventors: David Hall, Michael Hall, Cody Rees, Thomas Corie, Nathan Davis
  • Publication number: 20200406269
    Abstract: A method and a plant for producing secondary solid fuel (SSF) provide for removing fine and heavy waste from a flow of treated waste and further subdividing the remaining waste into intermediate waste and light waste. Only the fraction of intermediate waste is subjected to removal of chlorinated plastics (PVC). Advantageously, thanks to the fact that only a small fraction of the treated waste is subjected to removal of the chlorinated plastics, high efficiency in the treatment of waste and in the production of SSF is obtained. Preferably, the intermediate waste fraction is also subjected to removal of ferrous metals and non-ferrous metals, such as aluminum.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 31, 2020
    Inventors: Pietro Paolo Cella Mazzariol, Gian Francesco Galanzino
  • Publication number: 20200406270
    Abstract: A centrifuge rotor (10) has a closure (32) between a lower part (12) of the centrifuge rotor (10) and a cover (14). The closure has been improved such that proper single-handed operation is made possible. In particular, the closure (32) can be closed and detached again using just one hand. This means that the closure (32) has a simpler structure and can also be produced more cost-effectively.
    Type: Application
    Filed: December 17, 2018
    Publication date: December 31, 2020
    Applicant: Eppendorf AG
    Inventors: Steffen Kühnert, Christoph Knospe
  • Publication number: 20200406271
    Abstract: A centrifuge rotor (10) includes a closure (32) between a lower part (12) of the centrifuge rotor (10) and a cover (14). The centrifuge rotor has been improved such that proper single-handed operation is made possible. In particular, the closure (32) can be closed and detached again using just one hand. This means that the closure (32) has a simple structure and can also be produced cost-effectively.
    Type: Application
    Filed: December 12, 2018
    Publication date: December 31, 2020
    Applicant: Eppendorf AG
    Inventors: Steffen Kühnert, Christoph Knospe
  • Publication number: 20200406272
    Abstract: A centrifugal separator includes a rotor arrangement and a drive arrangement. A user of electric energy is arranged in the rotor arrangement. The centrifugal separator includes a rotary transformer, the rotary transformer including a transformer stator and a transformer rotor. The transformer stator and the transformer rotor are arranged adjacent to each other with an airgap therebetween. The transformer rotor includes a secondary coil and is rotatable together with the rotor arrangement. The secondary coil is electrically connected to the user of electric energy arranged in the rotor arrangement for providing the user of electric energy with an electric current. The user of electric energy may be an actuator, and/or a sensor, and/or a control unit.
    Type: Application
    Filed: February 19, 2019
    Publication date: December 31, 2020
    Applicant: ALFA LAVAL CORPORATE AB
    Inventor: Per-Gustaf LARSSON
  • Publication number: 20200406273
    Abstract: Methods and systems for coating with shear and moisture sensitive materials are disclosed. A method of coating a product includes filling an inner bellows chamber of a bellows, which is provided within and isolated from an outer bellows chamber of a tank, with a predetermined amount of the coating material. The method of coating the product further includes supplying a pressurized material to the outer bellows chamber to pressurize the coating material within the inner bellows chamber to an operating pressure, and supplying the coating material within the inner bellows chamber to a spray gun at the operating pressure. The method of coating also includes determining that a measured actual pressure is within a predetermined control range of the target pressure and subsequently coating the product by spraying the product with the coating material from the spray gun.
    Type: Application
    Filed: September 11, 2020
    Publication date: December 31, 2020
    Inventors: John Roos, Todd Frenk, Robert Sims, Benjamin S. Price
  • Publication number: 20200406274
    Abstract: A device is described for protecting a sensor window. The device includes a two-piece nozzle system and is configured for generating a first and a second fluid flow, a first piece of the two-piece nozzle system being fixedly situated with respect to the sensor window, and a second piece of the two-piece nozzle system being configured for assuming different positions with respect to the first piece of the two-piece nozzle system, and the two-piece nozzle system being aligned with respect to the sensor window to direct a predominant portion of the first fluid flow in parallel to the sensor window and to direct a predominant portion of the second fluid flow in the direction onto the sensor window.
    Type: Application
    Filed: June 22, 2020
    Publication date: December 31, 2020
    Inventor: Markus Schulz-Weiling
  • Publication number: 20200406275
    Abstract: An energy-saving shower having a user-friendly device includes a top spray module, an upper shower rod, and a lower shower rod, wherein a shoulder spray module is arranged between the upper shower rod and the lower shower rod. A shoulder spray of the shower prevents the hair of a user from getting wet during a shower, and exactly sprays water to shoulders to relieve shoulder pains, so that the user will feel comfortable during the shower, and the shower experience is improved.
    Type: Application
    Filed: May 24, 2020
    Publication date: December 31, 2020
    Applicant: Xiamen Easo Co., Ltd
    Inventors: Xiaoming Fujian Tu, Haitao Lu, Yuebin Yang, Ximin Chen
  • Publication number: 20200406276
    Abstract: The present disclosure discloses an anti-splash water outflow device comprises a water outflow body and an internal assembly. The internal assembly comprises an inner body that is rotatable relative to the water outflow body upon being impacted by water. The inner body is disposed with at least two spiral blades, and two adjacent spiral blades of the at least two spiral blades define a spiral water passage. The water flows into the water outflow body from the water inlet to impact the inner body to drive the inner body to rotate relative to the water outflow body, and the water flows through the spiral water passage, flows out of the outlet of the spiral water passage, flows spirally downward along an inner wall surface of the water outflow body, and sprays out of the water outlet to obtain an annular water spray shaped as a lampshade.
    Type: Application
    Filed: June 29, 2020
    Publication date: December 31, 2020
    Inventors: Xuedong WANG, Jiangcheng Zhang, Zhixin Lin, Chuanbao Zhu