Abstract: Multi-frequency neural treatments and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes at least reducing patient pain by applying a first electrical signal to a first target location of the patient's spinal cord region at a frequency in a first frequency range of up to about 1,500 Hz, and applying a second electrical signal to a second target location of the patient's spinal cord region at a frequency in a second frequency range of from about 2,500 Hz to about 100,000 Hz.

Abstract: Bacteria, cancer cells, fungus and other harmful cells located beneath the surface of a mammal body can be effectively destroyed by passing an electrical current through the area to be treated. Electrodes are positioned on either side of the area to be treated, for example, gums, fingers, arms, legs, feet and torso, and an electric current is caused to flow between the electrodes and through the area to be treated. The electric current will destroy the bacteria, cancer cells, fungus or other harmful cells.

Abstract: The present invention discloses a comb-like device for stimulation of hair re-growth on the epidermis of an area of skin of a subject and methods of stimulating hair re-growth for stimulation of hair re-growth.

Abstract: An implantable stimulator is provided for stimulating muscles or nerves. The implantable stimulator may comprise an array of electrodes for electrically stimulating at least one of a nerve or a muscle of a subject, and at least one processing device.

Abstract: A neurostimulation system includes an electromyographic (EMG) electrode; a neural electrode implantable in a deep cerebellar nuclei of a subject; a data acquisition unit in communication with the EMG electrode for receiving and transmitting a EMG signal; and a processor in communication with the data acquisition unit, the processor generates a EMG pattern based on the EMG signal and outputs a stimulation signal to the neural electrode when the EMG pattern is indicative of an abnormal motor movement. A method of modulating an abnormal motor movement of a subject by using said neurostimulation system.

Abstract: A wireless pacemaker network including an electronic pacemaker unit (1) that acts as a master in the pacemaker network, including an electrode portion (2) that is, according to its intended purpose, to be attached to a first body portion, and an electronics assembly; and an electronic pacemaker unit (1?) that acts as a slave in the pacemaker network. The electronic pacemaker unit (1?) including an electrode portion (2?) that is, according to its intended purpose, to be attached to a second body portion, and an electronics assembly connected with the electrode portion, which is configured to generate a pulse, in particular a voltage pulse, and to output it to the second body portion via the electrode portion; wherein the pacemaker unit (1) acting as the master and the pacemaker unit (1?) acting as the slave interact wirelessly for controlling the bodily function.

Abstract: A topical nerve activation patch includes a flexible substrate, a dermis conforming bottom surface of the substrate comprising adhesive and adapted to contact a dermis of a user, a flexible top outer surface of the substrate, a plurality of electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the flexible substrate, a power source, and electronic circuitry that generates an output voltage applied to the electrodes. The electronic circuitry includes a controller, a voltage monitoring circuit coupled to the controller, a current monitoring circuit coupled to the controller, a switch coupled to the controller and a two stage boosted voltage circuit coupled to the switch and the power source that is configured to increase a switch voltage level to approximately a half value of a final output voltage before increasing to the final output voltage.

Abstract: A system for stimulating phrenic nerves to provide smooth breathing patterns is provided. More specifically, by identifying contraction threshold voltages for muscles associated with each of the left and right portions of a patient's diaphragm, a phrenic nerve pacing signal customized for each phrenic nerve may be provided to a patient. More specifically, a voltage of a pacing voltage provided to a first phrenic nerve may be less than the contraction threshold while a voltage of a pacing voltage provided to a second phrenic nerve may be greater than the contraction threshold.

Abstract: A therapeutic or diagnostic device comprises a wearable electrodes garment including electrodes disposed to contact skin when the wearable electrodes garment is worn, and an electronic controller operatively connected with the electrodes. The electronic controller is programmed to perform a method including: receiving surface electromyography (EMG) signals via the electrodes and extracting one or more motor unit (MU) action potentials from the surface EMG signals. The method may further include identifying an intended movement based at least on features representing the one or more extracted MU action potentials and delivering functional electrical stimulation (FES) effective to implement the intended movement via the electrodes of the wearable electrodes garment.

Abstract: Disclosed are: a skin care device which determines whether, on the basis of a voltage fluctuation according to contact with the skin, the skin care device has been rubbed, and which blocks the output of current through an electrode when rubbing does not occur for at least a set time; and a control method therefor. The disclosed skin care device determines the state of the skin care device on the basis of sensing voltage corresponding to a change in current of a transformation module according to the outputting of alternating current into the skin through contact electrodes, and blocks the output of current of an electrode module if the skin care device is in a fixed state.

Abstract: An electric hearing prosthesis, wherein the electric hearing prosthesis includes an implantable portion configured to electrically stimulate a cochlea to evoke a hearing percept, and an external portion configured to be in wired communication with the implantable portion, wherein the electronic components of the implantable portion are all passive electronic components.

Abstract: A navigation system or combination of navigation systems can be used to provide one or more navigation modalities to track a position and navigate a single instrument in a volume. For example, both an Electromagnetic (EM) and Electropotential (EP) navigation system can be used to navigate an instrument within the volume. The two navigation systems may be used separately to selectively individually navigate the single instrument in the volume. Disclosed are also systems and processes to determine a shape of the single instrument either alone or in combination with the position of the instrument. The instrument may be navigated with the addition of tracking devices or with native or inherent portions of the instrument.

Abstract: A spinal cord stimulator includes: (1) a flexible substrate; (2) a power source embedded in the flexible substrate; (3) a controller embedded in the flexible substrate and connected to the power source; and (4) an array of electrodes, including an array of stimulation electrodes, disposed over the flexible substrate and connected to the controller, wherein the controller is configured to direct the array of stimulation electrodes to deliver a stimulation pattern to a spinal cord of a patient.

Abstract: A medical device may receive sensor data from sensing sources, and determine confidence levels for sensor data received from each of the plurality of sensing sources. Each of the confidence levels of the sensor data from each of the sensing sources is a measure of accuracy of the sensor data received from respective sensing sources. The medical device may also determine one or more therapy parameter values based on the determined confidence levels, and cause delivery of therapy based on the determined one or more therapy parameter values.

Abstract: A medical device is configured to sense a cardiac electrical signal and determine from the cardiac electrical signal at least one of a maximum peak amplitude of a positive slope of the cardiac electrical signal and a maximum peak time interval from a pacing pulse to the maximum peak amplitude. The device is configured to determine a capture type of the pacing pulse based on at least one or both of the maximum peak amplitude and the maximum peak time interval.

Abstract: An implantable pulse generator (IPG) is disclosed having an improved ability to steer anodic and cathodic currents between the IPG's electrodes. Each electrode node has at least one PDAC/NDAC pair to source/sink or sink/source a stimulation current to an associated electrode node. Each PDAC and NDAC receives a current with a magnitude indicative of a total anodic and cathodic current, and data indicative of a percentage of that total that each PDAC and NDAC will produce in the patient's tissue at any given time, which activates a number of branches in each PDAC or NDAC. Each PDAC and NDAC may also receive one or more resolution control signals specifying an increment by which the stimulation current may be adjusted at each electrode. The current received by each PDAC and NDAC is generated by a master DAC, and is preferably distributed to the PDACs and NDACs by distribution circuitry.

Abstract: An external control device for indicating whether a stimulation parameter set for use in a neurostimulator is available on a remote control in communication with the external control device is provided. The device includes a user interface configured for displaying the stimulation parameter set and an indicator that indicates whether the stimulation parameter set is available to the patient from the remote control. The device also includes control circuitry configured for, in response to input from the user (e.g., actuating the indicator), selectively turning the indicator on or off. The indicator may be an icon, and the icon may be a graphical depiction of a remote control. The user interface may be further configured for receiving additional input from the user, and the control circuitry may be further configured for, in response to the additional input from the user, programming the remote control with the stimulation parameter set.

Abstract: A wearable cardioverter defibrillator (“WCD”) latching connector system includes a receptacle positioned within a WCD monitor, and a connector configured to removably engage the receptacle.

Abstract: A dynamically adjustable multiphasic pulse system and method are provided. The dynamically adjustable multiphasic pulse system may be used as pulse system for a defibrillator or cardioverter.

Abstract: Concepts and technologies disclosed herein are directed to a smart automated external defibrillator (“AED”). According to one aspect of the concepts and technologies disclosed herein, the AED can present a menu that includes a plurality of modes. The plurality of modes can include a first responder mode, an Internet of Things (“IoT”), and a general use mode. The AED can receive, via an input component, a selection, from the menu, of a mode from the plurality of modes. In response to the selection, the AED can configure a network connectivity component in accordance with a setting specified in the mode.

Abstract: An apparatus for independent readiness determination for AED deployment includes a controller configured to detect an AED enclosure event corresponding to one or more AEDs registered to be disposed within one or more corresponding AED enclosures, where the controller is configured to communicate data for classifying an AED enclosure event into a predetermined event category, and further includes a communication interface configured to communicate a response action in response to data of the AED enclosure event satisfying one or more predetermined criteria for the predetermined event category. A method and a computer program product also perform the functions of the apparatus.

Abstract: In some examples, a coil electrode assembly includes a coil electrode including a plurality of windings and extending from an electrode proximal end to an electrode distal end, the coil electrode defining an electrode lumen from the electrode proximal end to the electrode distal end. The coil electrode assembly further includes an insulative tube extending within the lumen of the coil electrode such that the coil electrode extends along an outer surface of the insulative tube. The coil electrode is partially embedded within the insulative tube when the insulative tube is in an expanded state to maintain a spacing between the windings.

Abstract: The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering a new dual-frequency dynamic nuclear polarization (DNP) method that uses a microwave beam to polarize the spins of electrons and concomitantly act as a NMR transmitter.

Abstract: A method of treating dysautonomia in a human via transcranial magnetic stimulation is provided. The method includes positioning an induction device in proximity to a head region adjacent a prefrontal cortical brain region of the human and delivering magnetic stimulation to the prefrontal cortical region of the human by applying current to the induction device at a frequency that promotes inhibition (e.g., a frequency of about 5 Hertz or less, or certain types of theta bursts). The transcranial magnetic stimulation can introduce variability and/or have a modulatory or a disinhibitory effect on an autonomic nervous system of the human. For instance, the transcranial magnetic stimulation can increase a level of heart rate variability in the human by having a positive modulatory effect on the autonomic nervous system in which autonomic balance is achieved or restored as a result of the stimulation.

Abstract: Photobiomodulation therapy (PBMT) can be applied to a tender area on a subject's body to treat fibromyalgia. A light source device can be contacted to a subject's skin proximal to a tender area on the subject's body. A light signal (with wavelengths from the red to infrared part of the spectrum) can be applied in at least one of a pulsed operating mode, a continuous operating mode, and a super-pulsed operating mode through the light source device to the tender area. The light signal is applied for a time sufficient to stimulate a phototherapeutic response in the tender area to treat fibromyalgia.

Abstract: The present invention provides a digestive tract capsule endoscopy integrated with photodynamic diagnosis and therapy; the digestive tract capsule endoscopy integrated with photodynamic diagnosis and therapy includes an imaging system, a control system, a battery and a communication system, and the imaging system includes a fluorescent camera, diagnosis LED light sources and therapy LED light sources. In the digestive tract capsule endoscopy integrated with photodynamic diagnosis and therapy provided by the present invention, it changes a conventional optical image system into a fluorescent image system, which requires no extra equipment and has strong adaptability; the present invention can achieve integrated diagnosis and therapy of human body's internal cavities, e.g.

Abstract: A sublingual light therapy device for use in photonic infusion therapy of sublingual tissues. The disclosed device is optimized to direct therapeutic light directly to the targeted tissues while providing comfort and convenience to the patient.

Abstract: The present invention relates to a light emission control device for inhibiting accumulation of amyloid beta plaques, wherein light emission is controlled whereby nerve endings distributed in the epidermis or dermis layer under the skin surface within a specific region of the neck and the nape of the neck in an animal or human body are simulated with visible light energy for a predetermined period of time, and nitrergic nerve terminals connected to the stimulated nerve endings and the nervous system are induced to secrete a material, such as nitric oxide, which in turn relaxes the cerebral blood veins or lymphatic vessels in contact with the nitrergic nerve terminals to induce cerebral blood circulation or lymph circulation enhancement, thereby inhibiting the accumulation of amyloid beta plaques.

Abstract: Provided herein is a multifunctional aesthetic system including a housing, an electromagnetic array situated in the housing and having a plurality of electromagnetic radiation (EMR) sources, each EMR source configured to generate an EMR beam having a wavelength different than that of an EMR beam generated by another of the EMR sources, a controller in electronic communication with the array to operate two or more of the EMR sources to direct the EMR beam to a treatment area, and a sensor in electronic communication with the controller for providing feedback to the controller based on defined parameters to allow the controller to adjust at least one operating condition of the multifunctional system in response to the feedback.

Abstract: A phototherapy device for delivering light emitted by a light source to an infant. The phototherapy device includes two or more light pads configured to be optically connected to a light source via a connector. Light emitted by the light source is received by the connector and propagated through the connector to the light pads. The phototherapy device also includes a flexible garment configured to maintain the position of the pads on a front and back of an infant.

Abstract: The present disclosure relates to modulating neural activity within brainstem circuitry to evoke a certain bodily function (e.g., cardiorespiratory response) in a patient. A controller can configure a light signal (such as an infrared light signal) to deliver an amount of radiant exposure to a specific portion of the brainstem for a time. The specific portion of the brainstem can include brainstem circuitry that is the control center for the certain bodily function. The configured light signal can be delivered to the specific portion of the brainstem by an optrode for the time. During application, the light signal can deliver the amount of radiant exposure to the specific portion of the brainstem to evoke the certain bodily function.

Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.

Abstract: A casing holding one or more brachytherapy seeds for implanting in a patient, which in turn carry atoms of a radioactive element for radiotherapy treatment is filled with a viscous liquid in a manner preventing radiation from the one or more brachytherapy seeds from exiting the casing. The casing may include a metallic or non-metallic elongated tube configured for insertion into tissue or a vial for delivering a seed to a physician for insertion into a needle.

Abstract: A computer implemented method of determining a resultant treatment plan for a proton radiation therapy system based on given dose volume constraints, wherein the resultant treatment plan is optimized for treatment time comprises accessing the dose volume constraints and range information, wherein the range information indicates acceptable deviations from the dose volume constraints. Based on the proton radiation therapy system, the method further comprises accessing machine configuration information comprising a plurality of machine parameters that define a maximum resolution achievable in irradiating a patient. Further, the method comprises iteratively adjusting the plurality of machine parameters to values which decrease the maximum resolution and simulating a plurality of candidate treatment plans to generate a plurality of treatment plan results, wherein each treatment plan result comprises: a respective treatment time and a respective plan quality.

Abstract: A system (1) includes a device (12, 116 or 118) with memory with spectral volumetric image data generated by a spectrally configured computed tomography scanner including a radiation source and a radiation detector and an image guided system (14) configured to employ the spectral volumetric image data for an image guided procedure. A computer readable medium is encoded with computer executable instructions, where the computer executable instructions, when executed by a processor, causes the processor to: obtain spectral volumetric image data generated by a spectrally configured computed tomography scanner including a radiation source and a radiation detector, and employ the spectral volumetric image data for an image guided procedure. A method includes receiving spectral volumetric image data generated by a spectrally configured computed tomography scanner including a radiation source and a radiation detector, and utilizing he spectral volumetric image data for an image guided procedure.

Abstract: Systems and methods for implementing an adaptive therapy workflow that minimizes time needed to create a session patient model, select an appropriate plan for the treatment session, and treat the patient.

Abstract: The invention comprises a method and apparatus for using a multi-layer multi-color scintillation based detector element to image a tumor of a patient using a process of determining residual energies of positively charged particles after passing through the patient, the process comprising the steps of: (1) transmitting the positively charged particles at known energies through the patient and into a multi-layer detector element; (2) detecting first and second secondary photons, resultant from passage of the positively charged particles, respectively from a first layer of a first scintillation material and a second layer of a second scintillation material at two respective layer depths, where the first wavelength range differs from the second wavelength range; (4) determining residual energies of the positively charged particles, using output from the step of detecting; and (5) relating the residual energies to body densities to generate an image.

Abstract: A radiation treatment system may include a gantry configured to rotate around an object, a treatment head moving with the gantry, a plurality of imaging radiation sources configured to emit imaging beams toward the object, and one or more first detectors configured to detect at least a portion of the imaging beams. When the treatment head is delivering a treatment beam to the object, the plurality of imaging radiation sources and the one or more first detectors may be positioned outside at least a portion of a maximum treatment radiation region so as not to interfere with the treatment beam. At least one of the plurality of imaging radiation sources and the one or more first detectors may be positioned at or near an edge of the maximum treatment radiation region.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue to cause altered activity at a synapse between a neuron and a non-neuronal cell. In one embodiment, the energy is applied to cause persistent effects as a result of repeated application of energy within a predefined treatment window.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue (e.g., an organ) that include applying energy (e.g., ultrasound energy) into the tissue to cause altered activity at a synapse between a neuron and a non-neuronal cell. In one embodiment, the energy is applied to cause competing or opposing effects for bi-directional control of physiological processes.

Abstract: A method that may be executed by a device for calculating a reapplication time for sunscreen. The method may be implemented as lines of code that are executed by the device. The method includes receiving information associated with a reapplication of sunscreen, calculating the reapplication time for the sunscreen based, in part, on the information and displaying the reapplication time to a user.

Abstract: An emergency escape system for high-rise building includes a launcher installed in a launch room/station of a given floor in a skyscraper and suspended by a spring-loaded reel of cable which is counterbalanced by the weights of the launcher which has mechanisms for floor retraction and movement control incorporated to it, and a descending ride unit on a guide rail which engages with the launcher and which conveys an escapee or a load whose weight upsets the equilibrium of the two opposing forces and while the ride unit disengages from the launcher when the launcher has descended through the retracted floor, the launcher returns to the launch station to maintain the equilibrium of the weight balance, leaving the descending ride unit to continue its motion down the shaft with its human cargo/es until brought to rest by a brake system of arresting cables with or without brake linings and drums; before safely ejecting the escapee/s from the ride unit away from the shaft.

Abstract: In one aspect of the present invention, there is provided a modular respirator comprising an elongate filter unit having a filter inlet, a filter a filter outlet, and a replaceable fluid filter for filtering pollutants within the fluid. The elongate exhaust unit having an exhaust inlet, an exhaust outlet, and one or more one-way valves. A mask assembly having a mask for covering the oral and nasal passage of a user, a mask inlet at one end of the mask, a mask outlet at an opposite end of the mask, wherein the mask inlet is releasably fastened to the filter outlet, and the mask outlet is releasably fastened to the exhaust inlet.

Abstract: In a preferred embodiment, methods and systems for the control of the breathing gas supply from a pressure-leading supply conduit to one or more breathing masks of an oxygen emergency supply device in a passenger aircraft include an on/off valve arranged between the supply conduit and the one or more breathing masks. The valve can be blocked or released to control air supply based upon monitoring mass flow to the breathing masks. The valve, for example, is actuated to an open position until the error between the actual mass flow and a desired mass flow exceeds a maximal error value, whereupon the valve is actuated to a closed position until the error between the actual mass flow and the desired mass flow exceeds a minimal error value whereupon the valve is actuated to the open position and the mass flow monitoring cycle is repeated.

Abstract: A filter according to an embodiment include a filter main body provided with a sheet member, and a border portion of the filter main body includes a first region bent at least one time, and a second region formed in a flat shape and provided to be bendable and to provide softness to the filter main body.

Abstract: A connection arrangement for use with a wearable body harness includes a first connector having a first body component, a second body component, and an attachment element connected to each other by a rod having a longitudinal axis. The connection arrangement further includes a second connector removably connectable to the first connector. Each of the first body component, the second body component, and the attachment element are independently movable relative to each other about the longitudinal axis of the rod. The first connector and the second connector are removably connectable to each other via a locking and release mechanism between a first, locked configuration, where the first connector and the second connector are connected to each other, and a second, unlocked configuration, where the first connector and the second connector are disconnected from each other.

Abstract: A rope based fall protection device including a rotation unit, a brake unit, and a rope. A first end of the rope is connected to the rotation unit. The rope includes a first rope loop and a second rope loop that are wound around the rotation unit. A first retaining portion of a retaining ring is sleeved on the first rope loop and a second retaining portion thereof is sleeved on the second rope loop, such that the rope forms a rope section which has a fixed length between the second retaining portion and the first end and is wound around the rotation unit. When a free end of the rope is pulled by an external force to release the rope wound around the rotation unit in a direction away from the rotation unit, the retaining ring is broken to release the rope section of the rope. The external force is greater than or equal to a pulling force generated by a user's free fall.

Abstract: An energy-absorbing structure for a tether line includes a helical spring and a first connector for securing a first end of the helical spring to a first fastener (such as a support cable section, an eye bolt or an eye nut). The first connector has an externally threaded portion for threadedly receiving the first end of the helical spring. A sleeve is provided on the connector, extending over at least part of the first end of the helical spring and the external threaded portion of the connector, for retaining the helical spring on the connector. Additionally or alternatively, the connector includes a tapered portion extending from the inner end of the externally threaded portion.

Abstract: A method of protecting life, property, homes and businesses from wild fire by applying environmentally-clean anti-fire (AF) liquid spray using a wireless network supported by GPS-tracking techniques GPS-specified maps and task reports are generated on the wireless network informing when environmentally-clean anti-fire (AF) chemical liquid should be spray applied to said GPS-specified private property using a GPI-tracking AF chemical liquid spraying system prior to arrival of wild fires. The preferred clean anti-fire chemical liquid used does not depend on water to extinguish fire, so that, even after a month or two after spray application on buildings and dry brush around the neighborhood, the clean anti-fire chemical continues to work by stalling the ability of a wild fire to advance and consume property and homes.

Abstract: A portable fuel container configured to prevent liquid fuel contained therein from being entirely emptied from the container. The amount of liquid fuel retained in the container can be sufficient to maintain a fuel-to-air ratio in the container at a fuel-rich level that prevents combustion within the container if the container were to be placed near an ignition source or if an ignition source were to somehow enter the container. The container can also include other safety features such as, for example, a flash suppressor located at the fill opening, an extra wide fill opening, and/or an easily controllable dispensing spout. When a flash suppressor is employed, the perforations in the flash suppressor can be configured to retain fuel therein after fuel has been dispensed from the container and the flash suppressor is no longer submerged in fuel.