Patents Issued in February 11, 2021
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Publication number: 20210038089Abstract: A medical device for measuring blood flow through a blood vessel of a mammal includes a conductive elastomer having a variable resistance. A frame is at least partially surrounding at least a portion of the conductive elastomer, the conductive elastomer is suspended within the frame. A mechanical amplification element is slidably engaged to the conductive elastomer, the mechanical amplification element being configured to slide within the frame and to contact skin of the mammal over the blood vessel when the frame is positioned over the blood vessel, the mechanical amplification element being configured to be displaced when the artery pulsates and changes the resistance of the elastomer.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Inventors: Philippe Lange, Giovanni Amoroso, David Lawrence Camp, JR., Gabriele Buttignol, Gerrit de Vries
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Publication number: 20210038090Abstract: Provided are a diagnostic device and a diagnostic method for predicting fractional flow reserve (FFR) and diagnosing coronary artery lesions via a coronary angiography-based machine learning algorithm. A deep learning-based diagnostic method for diagnosing an ischemic lesion includes: obtaining an angiography image of a patient's blood vessel; extracting a region of interest (ROI) from the angiography image; acquiring diameter information of the blood vessel in the ROI; extracting morphological features of the blood vessel based on the diameter information; and obtaining a predictive FFR value by inputting the morphological features to an artificial intelligence (AI) model and determining whether a lesion is an ischemic lesion.Type: ApplicationFiled: August 5, 2020Publication date: February 11, 2021Inventors: Soo Jin KANG, June Goo LEE, Hyung Joo CHO
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Publication number: 20210038091Abstract: Methods and systems for monitoring blood pressure in a person are disclosed. A method for monitoring a blood pressure in a person involves transmitting millimeter range radio waves over a three-dimensional (3D) space below the skin surface of a person, receiving radio waves on multiple receive antennas, the received radio waves including a reflected portion of the transmitted radio waves that is reflected by blood in a blood vessel in the 3D space, isolating a signal that corresponds to the portion of the transmitted radio waves that is reflected by blood in the blood vessel in response to receiving the radio waves on the multiple receive antennas, and outputting a signal that corresponds to a blood pressure level in the person in response to the isolated signal.Type: ApplicationFiled: October 15, 2020Publication date: February 11, 2021Inventor: Michael A. LEABMAN
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Publication number: 20210038092Abstract: A sleep monitor includes a layered sensor that includes at least one substrate layer that includes multiple laterally adjacent substrates. The substrate layer may be formed by interdigitating fingers of a first sheet with fingers of a second sheet. Combining multiple substrates in a single layer of a layered sensor may allow multiple materials and/or sensing mechanisms to be combined together in a single layer.Type: ApplicationFiled: July 15, 2020Publication date: February 11, 2021Inventors: Ali M. Amin, Yindar Chuo, Zijing Zeng
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Publication number: 20210038093Abstract: A method for blood flow assessment in an arteriovenous (AV) fistula includes steps of: emitting a carrier radio wave toward the AV fistula, and receiving a return wave signal; generating a transmission signal based on the return wave signal; recovering a digital signal from the transmission signal, performing a digital filtering process on the digital signal to result in a filtered signal, and generating a plurality of graphic files based on a waveform of the filtered signal; and performing image recognition on the graphic files, and outputting a result of the image recognition as a result of the blood flow assessment of the AV fistula.Type: ApplicationFiled: August 5, 2020Publication date: February 11, 2021Applicant: CardiacM CO., Ltd.Inventors: Teh-Ho TAO, Tai-Been CHEN
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Publication number: 20210038094Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.Type: ApplicationFiled: September 11, 2020Publication date: February 11, 2021Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Shriram Raghunathan, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley, Sean Quinlan
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Publication number: 20210038095Abstract: A wearable measuring system configured for determining a blood pressure of a user, including: a first measuring unit including a PPG sensor, a first voltage measuring electrode and a first current injecting electrode; and a second measuring unit including a second voltage measuring electrode and a second current injecting electrode. The first measuring unit is removably attachable to a user's body first location such that a PPG signal can be measured by a PPG sensor at the first location, and the second measuring unit is removably attachable to a user's body second location, such that an ECG and an ICG signal can be measured between the first and second locations. The wearable measuring system further includes a signal processing module configured for processing the measured ECG, ICG and PPG signals to determine a blood pressure value.Type: ApplicationFiled: April 11, 2018Publication date: February 11, 2021Inventors: Martin Proença, Josep Sola i Caros, Olivier Chételat, Jonas Racine
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Publication number: 20210038096Abstract: Systems and methods are disclosed to measure a PPG signal. In some embodiments, a method may include capturing a plurality of frames of a subject; tracking the position of a region of interest of the subject in each of the plurality of frames; creating a first time series signal, a second time series signal, and third time series signal corresponding with respective color channels of the plurality of frames; normalizing the first, second, and third time series signals, combining the normalized first time series signal, the normalized first time series signal, and the normalized first time series signal into a combined signal; creating a spectral signal from the combined signal; and extracting the PPG signal from the spectral signal.Type: ApplicationFiled: May 26, 2020Publication date: February 11, 2021Applicant: RAPSODO PTE. LTD.Inventors: Kelvin Yeo Soon KEAT, Batuhan OKUR
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Publication number: 20210038097Abstract: An image processing apparatus including a memory and a processor is provided. The image processing apparatus is configured to perform selecting one of data compression processing modes in response to a user input, and executing, according to the selected data compression processing mode, data compression processing on an input captured image based on an inter-frame prediction. The image processing apparatus is further configured perform generating a compressed image from the executed data compression processing. A group of pictures with respect to the generated compressed image is different according to the data compression processing modes. When receiving a request for acquiring vital information from a person captured in the input captured image, one of the data compression processing modes is selected so that the generated compressed image is configured by I pictures only.Type: ApplicationFiled: October 22, 2020Publication date: February 11, 2021Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.Inventors: Masao HAMADA, Tadanori TEZUKA, Tsuyoshi NAKAMURA
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Publication number: 20210038098Abstract: An apparatus for measuring bio-information may include a pulse wave sensor that may measure a pulse wave signal from an object in contact with a measurement surface. The apparatus may include a force sensor that may measure a contact force between the pulse wave sensor and the object. The apparatus may include a fastener configured to fasten the pulse wave sensor to an electronic device such that the pulse wave sensor is rotatable around a center axis in a length direction of the pulse wave sensor. The apparatus may include a processor that may determine a direction in which a measurement region of the pulse wave signal or the measurement surface of the pulse wave sensor is oriented, select a measurement mode from among a plurality of measurement modes, and estimate bio-information of the object.Type: ApplicationFiled: March 18, 2020Publication date: February 11, 2021Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Jeong Eun HWANG, Byung Hoon KO, Jong Wook LEE, Youn Ho KIM
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Publication number: 20210038099Abstract: A cable for use with a pressure monitoring catheter, the catheter including an inflatable balloon forming a fluid chamber for pressure measurement. The cable has a first end operably connectable to the catheter, a second end operably connectable to a monitor providing pressure displays, and a printed circuit. The cable includes one or both of the filter system to enable collection and analysis of data and an adjustment feature to adjust pressure values in response to patient movement.Type: ApplicationFiled: July 31, 2020Publication date: February 11, 2021Applicant: Sentinel Medical Technologies, LLCInventors: Timothy McKinney, Marc-Alan Levine, Michael Leedle
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Publication number: 20210038100Abstract: An intrauterine balloon apparatus to augment uterine birthing forces and assist fetal descent during parturition is provided. The body of the balloon apparatus begins packaged in a compressed state minimizing volume, enabling delivery through the birth canal. The apparatus is advanced to a proximal uterine location and deployed for operation by introducing a pressurized agent through its conduit, causing the body to expand and apply directional forces towards the infant and birth canal. The balloon body is shaped to apply pressures dispersed towards the infant and the bidirectional conduit enables fluid conduction as the infant descends. After the infant has successfully descended and been delivered through the birth canal, pressure within the balloon body is relieved through the conduit thereby collapsing the volume of the balloon body and enabling retraction through the birth canal.Type: ApplicationFiled: October 22, 2020Publication date: February 11, 2021Inventors: Ed CHINCHOY, Jay SNELL, James KELLEY
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Publication number: 20210038101Abstract: This disclosure relates to electrophysiology cardiac ablation devices, methods, and systems. In particular, this disclosure relates to devices, methods, and systems that create a reversible non-ablative blockade of cardiac tissue, test the cardiac tissue, and ablate the cardiac tissue.Type: ApplicationFiled: February 8, 2019Publication date: February 11, 2021Inventors: Kenneth S. Wu, Douglas Michael Ackermann
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Publication number: 20210038102Abstract: A system and method for neural-network-based atrial fibrillation detection with the aid of a digital computer are provided. Electrocardiography (ECG) features and annotated patterns of the features are maintained in a database, at least some of the patterns associated with atrial fibrillation. A classifier is trained based on the annotated patterns, the classifier implemented by a convolutional neural network. A representation of an ECG signal recorded by one or more ambulatory monitors is received. ECG features in the representation falling within each of the temporal windows are detected. The trained classifier is used to identify patterns of the ECG features. At least one matrix with weights for the patterns are generated. A value indicative of whether portions of the representation are associated the patient experiencing atrial fibrillation is calculated. That one or more of the portions are associated with the patient experiencing atrial fibrillation is determined.Type: ApplicationFiled: October 26, 2020Publication date: February 11, 2021Inventors: Rodney Boleyn, Ezra M. Dreisbach, Chuck Dulken, Gust H. Bardy
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Publication number: 20210038103Abstract: An electrophysiology system including signal channels each of which processes an electrophysiological signal along a signal path extending from an input port that receives the analog electrophysiological signal, via an adjustable gain element that amplifies the electrophysiological signal, and via an ADC element that converts the analog signal into a corresponding digital signal, to an output port. The system further includes a monitoring element that generates a monitoring signal representative of a DC component of the electrophysiological signal and a gain control element that generates a control signal responsive to the monitoring signal. The control signal controls the gain setting of the gain element to cause a decrease in gain, if an increase in the magnitude of the DC component is determined; and/or an increase in gain, if a decrease in the magnitude of the DC component is determined.Type: ApplicationFiled: March 12, 2019Publication date: February 11, 2021Inventors: Sigge Nejst Larsen, Victor Shadbolt, David P. MacAdam, Harold Wodlinger
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Publication number: 20210038104Abstract: A method of computing a heart rate value compensates for noise derived from the subject, the sensor, the transmission, and/or other variables that can lead to false R-peak detection or missed R-peak detection. The method computes an updated heart rate based on a window of approximately ten seconds of digitized ECG readings broadcast from a sensor. A new value is calculated approximately every second such that the window of ECG readings overlaps considerably between consecutive calculations. The method compensates for noisy data by discarding heart rate samples that differ by more than a threshold amount from a previously calculated heart rate value. The threshold is adjusted based on a standard deviation of differences between heart rate samples. Prior to calculating a heart rate value, a forward-looking, pre-filter logic may be applied in situations where the raw data has an extremely low signal-to-noise ratio.Type: ApplicationFiled: January 14, 2020Publication date: February 11, 2021Applicant: SPORTS DATA LABS, INC.Inventors: Vivek KHARE, Viprali BHATKAR, Mark GORSKI, Stanley MIMOTO, Anuroop YADAV
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Publication number: 20210038105Abstract: A system and method for facilitating a cardiac rhythm disorder diagnosis based on subcutaneous cardiac monitoring data with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.Type: ApplicationFiled: October 26, 2020Publication date: February 11, 2021Inventors: Gust H. Bardy, Ezra M. Dreisbach
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Publication number: 20210038106Abstract: Provided are sensor units that include conductive segments disposed in a flexible sensing layer material, which sensor units are useful in EEG and other diagnostic applications. The sensor units are capable of maintaining electrical contact with a subject's skin in the absence of electrolytic gel, and provide robust signal collection with minimal signal degradation over time. Also provided are related methods of making the disclosed sensor units as well as methods of use.Type: ApplicationFiled: September 9, 2020Publication date: February 11, 2021Inventors: Arjun RAMAKRISHNAN, Michael L. PLATT, Naz BELKAYA, Rimjhim CHAUDHARY
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Publication number: 20210038107Abstract: In one embodiment, a method to detect noise levels in electrocardiogram (ECG) signals is described. The method includes connecting to at least three sensing electrodes and obtaining a signal from each of the at least three sensing electrodes. The method also includes defining at least three channels between the at least three electrodes. The method includes calculating a morphological similarity value of at least one combination of the at least three channels based at least in part on the obtained signal from each of the at least three sensing electrodes and determining a noise level based at least in part on the calculated morphological similarity value.Type: ApplicationFiled: August 5, 2020Publication date: February 11, 2021Applicant: West Affum Holding Corp.Inventor: JAEHO KIM
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Publication number: 20210038108Abstract: A computer implemented method and system are provided for detecting premature ventricular contractions (PVCs) in cardiac activity. The method and system obtain cardiac activity (CA) signals for a series of beats, and, for at least a portion of the series of beats, calculate QRS scores for corresponding QRS complex segments from the CA signals. The method and system calculate a variability metric for QRS scores across the series of beats, calculate a QRS complex template using QRS segments from the series of beats, calculate correlation coefficients between the QRS complex template and the QRS complex segments, compare the variability metric to a variability threshold and the correlation coefficients to a correlation threshold, and designate the CA signals to include a predetermined level of PVC burden based on the determining.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Inventors: Jong Gill, Fujian Qu, Neha Malhotra, Stuart Rosenberg, Gene A. Bornzin, Fady Dawoud
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Publication number: 20210038109Abstract: According to one embodiment, a magnetic sensor includes a first sensor element and a first interconnect. The first sensor element includes a first magnetic layer, a first opposing magnetic layer, and a first nonmagnetic layer provided between the first magnetic layer and the first opposing magnetic layer. A first magnetization of the first magnetic layer is aligned with a first length direction crossing a first stacking direction from the first magnetic layer toward the first opposing magnetic layer. At least a portion of the first interconnect extends along the first length direction. The first interconnect cross direction crosses the first length direction and is from the first sensor element toward the portion of the first interconnect. A first electrical resistance of the first sensor element changes according to an alternating current flowing in the first interconnect and a sensed magnetic field applied to the first sensor element.Type: ApplicationFiled: October 28, 2020Publication date: February 11, 2021Applicant: KABUSHIKI KAISHA TOSHIBAInventors: Hitoshi IWASAKI, Akira KIKITSU, Satoshi SHIROTORI
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Publication number: 20210038110Abstract: The present disclosure discloses a method for synthesizing high-quality magnetic resonance images, wherein the method expands the value ranges of echo time TE and repetition time TR in a magnetic resonance signal formula to negative intervals, and expands the contribution of proton density PD to a negative power. The method can effectively reduce the influence of the measurement error of quantitative magnetic resonance imaging tissue parameters on the tissue contrast of the synthetic magnetic resonance image, and can obviously improve the tissue contrast of the synthetic magnetic resonance image. This method will significantly improve the imaging quality of synthetic magnetic resonance imaging, and promote its detection effect in neuroscience and clinical lesions. This method is expected to improve the imaging quality of synthetic magnetic resonance imaging and promote its detection effect in neuroscience and clinical lesions.Type: ApplicationFiled: September 29, 2020Publication date: February 11, 2021Inventors: Hongjian HE, Jun LI, Xiaozhi CAO, Qiuping DING, Jianhui ZHONG
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Publication number: 20210038111Abstract: A novel method and system for enhanced-resolution THz imaging whereby an enhanced-resolution THz image is developed by deconvolution of the original THz image that is developed using THz signals that are manipulated in time-domain and/or in frequency-domain and a point spread function (PSF) that is developed according to an equation wherein said THz signals in time-domain and/or frequency-domain are input parameters. By using this method and system, enhanced-resolution THz images are developed for detecting traces of symptoms of COVID-19 as small as a drop of water. Said novel method and system for enhanced-resolution THz imaging is used for developing a device, and method, that is: (a) rapid, (b) economical, (c) able to perform measurements remotely, (d) non-invasive. This device, and method, is capable of detecting symptoms of COVID-19 such as runny nose, congestion, and cough. The person under examination may or may not wear a face covering mask.Type: ApplicationFiled: October 21, 2020Publication date: February 11, 2021Inventor: Kiarash Ahi
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Publication number: 20210038112Abstract: A needle is provided that has terminals located at or near its tip. The terminals are connectable to an impedance calculating circuit configured to enable the impedance calculating circuit to apply an alternating current input electrical signal to the terminals. The terminals are further configured to enable the impedance calculating circuit to measure a resultant electrical signal and calculate an impedance of biological tissue surrounding the tip. The needle may further include light transmitting media, that extends along the needle, and that is connectable to a light circuit. The light circuit may include an emitter/detector pair for transmitting light from the emitter, along the media, and emitting the light from the tip. A reflection of the emitted light may be transmitted from the tip to the detector and the light circuit may calculate the light absorption of the tissue.Type: ApplicationFiled: April 3, 2019Publication date: February 11, 2021Inventors: Pieter Rousseau Fourie, Tys Van Der Merwe
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Publication number: 20210038113Abstract: A sensing apparatus for measuring at least one parameter includes at least one sensor for detecting at least one parameter and outputting a signal representative of the parameter. The sensing apparatus includes a memory for storing data and computer instructions and a communication component configured to transmit data representative of a value associated with the at least one parameter. A processor of the sensing apparatus communicates with the at least one sensor, the memory and the communication component. The processor receives output signals from said at least one sensor, and calculates at least one parameter based on computer instructions stored in the memory. The parameter is formatted in a human interface device (HID) compliant protocol, and provided to the communication component, which transmits the at least one HID compliant parameter value to a remote processing device.Type: ApplicationFiled: October 21, 2020Publication date: February 11, 2021Inventors: Steven Petrucelli, Jack Ko
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Publication number: 20210038114Abstract: A respiratory gas flow coupling includes a device connector having a female receptacle or male nipple with a side-oriented leak path. A patient accessory connector has a male nipple or female receptacle adapted to connect with the female receptacle or male nipple of the device connector. The patient accessory connector seals the side-oriented leak path of the female receptacle or male nipple of the device connector when the patient accessory connector is connected with the device connector. The side-oriented leak path is disposed at a position such that a shorter male nipple or female receptacle of an incompatible patient accessory connector which is shorter than the male nipple of the patient accessory connector does not seal the side-oriented leak path when the incompatible patient accessory connector with the shorter male nipple is connected with the device connector.Type: ApplicationFiled: April 25, 2019Publication date: February 11, 2021Inventor: ASHISH MISHRA
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Publication number: 20210038115Abstract: In one aspect, a computer-implemented method includes receiving a signal corresponding to impedance across a patient's chest cavity; filtering the signal using one or more filters that reduce noise and center the signal around a zero baseline; adjusting an amplitude of the filtered signal based on a threshold value; separating the amplitude-adjusted signal into component signals, where each of the component signals represents a frequency-limited band; detecting a fractional phase transition of a component signal of the component signals; selecting a dominant component signal from the component signals based on amplitudes of the component signals at a time corresponding to the detected fractional phase transition; determining a frequency of the dominant component signal at the time corresponding to the detected fractional phase transition; and determining a respiratory rate of the patient based on the determined frequency.Type: ApplicationFiled: July 7, 2020Publication date: February 11, 2021Inventors: Carlos A. Ricci, Vladimir V. Kovtun, Scott Thomas Mazar
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Publication number: 20210038116Abstract: A cough detection, analysis, and communication platform may be provided. The platform may comprise methods, systems, and a devices for detecting, analyzing, and communicating cough detection data. A cough detection device may comprise at least one microphone and analytic firmware used to employ methods of detecting, analyzing, and communicating the cough detection data. The analytic software may be updated to use the appropriate algorithms for an individual or corresponding demographic based on, for example, age and disease, with abnormal cough frequency components, abnormal cough frequency profiles, and alert thresholds. The cough detection device may be configured to communicate cough detection data to a server. The server, in turn, may be operative to process and communicate the data to a third party, such as, for example, a physician. Systems may further be operative to provide a user interface (e.g., mobile or web applications) for interfacing with the platform.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Inventor: Steven P. Schmidt
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Publication number: 20210038117Abstract: A system for determining continuous positive airway pressure (CPAP) and interface type for a user which includes one or more processors, one or more computer readable media, and one or more modules maintained on the one or more computer readable media that, when executed by the one or more processors, cause the one or more processors to perform operations including receiving an initial CPAP pressure setting for a user, monitoring a residual apnea hypopnea of the user, and determining an optimal CPAP pressure setting for the user based on the residual apnea hypopnea of the user.Type: ApplicationFiled: March 27, 2020Publication date: February 11, 2021Inventor: Bijan Sadrnoori
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Publication number: 20210038118Abstract: We describe a capnometer for detecting a concentration of a component in a gas, wherein said gas is inhaled and/or exhaled by a patient, said capnometer comprising: an air flow region through which said gas passes to and/or from said patient's lung; a mid-IR semiconductor emitter configured to provide IR light at a wavelength in the range 3-5 ?m; a mid-IR semiconductor detector to detect said IR light; a reflector to reflect said IR light emitted by said emitter; wherein said emitter, said detector and said reflector are arranged such that said IR light emitted by said emitter passes through said air flow region via said reflector to said detector. The reflector is selected from a Fresnel reflector and a reflective diffractive optical element, such as.a Fresnel zone plate.Type: ApplicationFiled: March 13, 2019Publication date: February 11, 2021Inventors: Julian CARTER, Jeremy WALSH, Russell OVEREND, Craig WHITEHILL, Colin PHIMISTER
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Publication number: 20210038119Abstract: A method of non-invasively monitoring the respiration of a patient comprises: transmitting ultrasound into the body toward an internal structure of the patient's body, the internal structure being one of the liver, the spleen or a kidney; selecting a depth range; measuring the phase of ultrasound echo signals from the internal structure at multiple points along the depth range for at least a first and a second echo signal, the first and second echo signals being received at different times; detecting the motion of the internal structure within the patient's abdomen by reference to differences in the measured phase between the first and the second echo signals; and thereby monitoring the respiration of the patient by associating movement of the internal structure with movement caused by respiration.Type: ApplicationFiled: October 28, 2020Publication date: February 11, 2021Inventors: Nicolas SOUZY, Morten ERIKSEN, Nicolay BERARD-ANDERSEN
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Publication number: 20210038120Abstract: A method and system for monitoring neuromuscular blockade in patients during surgical procedures. A stimulator provides stimulation to a nerve of the patient, such as train-of-four (TOF). Following such stimulation, the system and method creates a predicted recovery trend for the patient that is based upon measured recovery trend and a recovery model. The recovery model estimates a recovery trend for the patient based on initial model parameter values. The recovery model creates a predicted recovery trend that is used to estimate a recovery time for the patient. The trend values from the patient are monitored and compared to the predicted trend values throughout the operation as long as the NMT measurement is on. During recovery, the recovery model and recovery time estimates are updated based on the recovery trend being formed from measurements of the patient.Type: ApplicationFiled: August 9, 2019Publication date: February 11, 2021Applicant: GE Precision Healthcare LLCInventors: Helena Liisa Anneli Batsman, Kimmo Henrik Uutela, Markku Erik Spoof
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Publication number: 20210038121Abstract: System and method to monitor an exercise posture of at least one user are provided. The system includes a flexible substrate placed on top of a mat coupled with one or more contact sensors configured to generate a contact signal upon making a contact of at least one part of a body of the corresponding at least one user with the mat while performing the at least one exercise on the mat. The system further includes a processing subsystem configured to receive the contact signal, and to receive an angle signal generated by at least one inertial sensor upon measuring an angle of at least one user while performing the at least one exercise, to generate a combined signal, to compare the combined signal with a pre-defined set of exercise posture signals and to monitor the exercise posture of the at least one user.Type: ApplicationFiled: November 2, 2018Publication date: February 11, 2021Inventors: Muralidhar SOMISETTY, Pranav KANUPARTHI, Sankar DAS IGA
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Publication number: 20210038122Abstract: A method for detecting body movements of a sleeping person includes continuously creating three-dimensional images using an imaging unit and providing distance measurement values pixel by pixel. A two or three-dimensional height profile has points on a surface, or on, or next to the person. The profile is stored and available for each time. A range indicating a body part or area depending on a reference point or range is selected as a first region of interest. Periods of changes of the profile of the first region exceeding a first threshold value, and intervals therebetween are determined. Noise values of the profile are determined pixel by pixel for the intervals. Further changes of the profile exceeding a second threshold value in the intervals are determined, considering the noise value pixel by pixel. The periods and further periods of changes of the profile are registered as body movements.Type: ApplicationFiled: January 21, 2019Publication date: February 11, 2021Inventors: BERNHARD KOHN, MARKUS GALL, CHRISTOPH WIESMEYR, HEINRICH GARN, MARKUS WASER
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Publication number: 20210038123Abstract: A method, including obtaining respective first reactions of a recipient to a series of sounds subjected to the recipient of a hearing prosthesis, the first reactions being directly related to the recipient's ability to hear the series of sounds, obtaining respective second reactions of the recipient to the series of sounds, the second reactions being different in kind than the first reactions, and fitting the hearing prosthesis based at least in part on both the first reactions and the second reactions.Type: ApplicationFiled: February 6, 2019Publication date: February 11, 2021Inventors: Alexander VON BRASCH, Stephen FUNG
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Publication number: 20210038124Abstract: The lancet device includes a housing and a lancet having a puncturing element. The lancet is disposed within the housing and is adapted for axial movement between an initial or pre-actuated position wherein the puncturing element is retained within the housing, and a puncturing position wherein the puncturing element extends through a forward opening in the housing. The lancet device includes a drive spring disposed within the housing for biasing the lancet toward the puncturing position, and a retraction or return spring for returning the lancet to a position within the housing where the puncturing element is disposed within the housing. The retraction spring thereafter maintains engagement with the lancet to assist in preventing the puncturing element from again projecting outward from the forward opening in the housing.Type: ApplicationFiled: October 26, 2020Publication date: February 11, 2021Inventors: Jacek Grzegorz Karbowniczek, Wlodzimierz Rutynowski
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Publication number: 20210038125Abstract: The concentration of substance in blood is measured non-invasively, with high accuracy and with simple configuration. Laser light 100 generated by a light source 10 is locally irradiated on the body epithelium F of a subject, and the resulting diffused reflected light 200 is detected by a light detector 40. The laser light 100 has a wavelength of 9.26 ?m. The laser light 100 is generated by converting and amplifying pulsed excitation light 101 from an excitation light source 11 to a long wavelength. A plate-shaped window 300 that is transparent to mid-infrared light is brought in close contact with the body epithelium F. The glucose concentration in interstitial fluid can be calculated using normalized light intensity calculated from a signal ratio of signals from a monitoring light detector 16 and light detector 40.Type: ApplicationFiled: September 29, 2020Publication date: February 11, 2021Applicant: National Institutes for Quantum and Radiological Science and TechnologyInventor: Koichi YAMAKAWA
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Publication number: 20210038126Abstract: A multimodal needle comprises a plurality of micro-electrodes for electrochemical sensing. Each micro-electrode comprises a core of conducting material, insulating material surrounding the core, and a layer of metal or metal oxide nano-structures deposited on tips of the micro-electrodes at a first end for interfacing with a target sensing site. Such a multimodal needle is particularly useful for identifying tissue around the needle tip.Type: ApplicationFiled: March 6, 2019Publication date: February 11, 2021Inventors: Romeo-Robert RACZ, Andreas SCHAEFER
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Publication number: 20210038127Abstract: Systems and methods are provided for determining levels of a target analyte in a biological sample. A transdermal sampling and analysis device may include a substrate, at least one disruptor mounted on the substrate, a reservoir configured to collect and contain a biological sample, at least two electrodes, and an electrochemical bioassay configured to determine levels of a target analyte in the biological sample. The at least one disruptor of the transdermal sampling and analysis device may be configured to generate a localized heat capable of altering permeability characteristics of a stratum corneum layer of skin of an organism.Type: ApplicationFiled: June 13, 2020Publication date: February 11, 2021Inventors: Helena Woodvine SNYDER, Vikas BHATIA, John Frederick CURRIE, Emil F. JACHMANN
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Publication number: 20210038128Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.Type: ApplicationFiled: October 23, 2020Publication date: February 11, 2021Inventors: Sebastian Bohm, Daiting Rong, Peter C. Simpson
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Publication number: 20210038129Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.Type: ApplicationFiled: October 28, 2020Publication date: February 11, 2021Inventors: Sebastian Bohm, Daiting Rong, Peter C. Simpson
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Publication number: 20210038130Abstract: A method and system for monitoring analytes in the circulatory system of an individual is provided. A biological sensor is implanted in the bone marrow of a patient and may be self contained within a housing. The biological sensor measures physiological parameters of a patient, including analytes, on a fixed or adjustable schedule. The biological sensor includes a control unit having a transmitter and an energy source for providing energy to the control unit. The biological sensor may be used to adjust other medical treatments and devices in a closed or semi closed loop mechanism and/or predict patient treatment.Type: ApplicationFiled: March 11, 2019Publication date: February 11, 2021Inventors: Jeffrey Valk, Timothy Valk
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Publication number: 20210038131Abstract: A sensor inserter for a physiological characteristic sensor includes a housing that defines a track system that extends from a bottom of the housing toward a top of the housing. The sensor inserter includes a striker assembly movable relative to the housing between a first state, a second, cocked state and a third, disposal state. The striker assembly is movable from the second, cocked state to the third, disposal state to couple the physiological characteristic sensor to an anatomy. The striker assembly includes a lock beam that engages with the track system as the striker assembly moves between the first state, the second, cocked state and the third, disposal state. In the third, disposal state the lock beam inhibits movement of the striker assembly from the third, disposal state to the first state.Type: ApplicationFiled: August 6, 2019Publication date: February 11, 2021Inventors: Xin X. Li, Zhiyong Liu, Matthew William Yavorsky
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Publication number: 20210038132Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.Type: ApplicationFiled: October 14, 2020Publication date: February 11, 2021Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATIONInventors: Boris P. Kovatchev, Marc D. BRETON, Stephen D. PATEK
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Publication number: 20210038133Abstract: A system, apparatus, and device estimate the state of the glucose metabolism of the subject based on a correlation between a blood glucose level of the subject acquired in advance and an index which is based on the pulse wave of the subject associated with the blood glucose level.Type: ApplicationFiled: October 27, 2020Publication date: February 11, 2021Applicant: KYOCERA CorporationInventor: Hiromi AJIMA
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Publication number: 20210038134Abstract: A system and method for controlling and monitoring a diabetes-management system through the use of a model that predicts or estimates future dynamic states of glucose and insulin from variables such as insulin delivery or exogenous glucose appearance as well as inherent physiological parameters. The model predictive estimator can be used as an insulin bolus advisor to give an apriori estimate of postprandial glucose for a given insulin delivery profile administered with a known meal to optimize insulin delivery; as a supervisor to monitor the operation of the diabetes-management system; and as a model predictive controller to optimize the automated delivery of insulin into a user's body to achieve a desired blood glucose profile or concentration. Open loop, closed-loop, and semi-closed loop embodiments of the invention utilize a mathematical metabolic model that includes a Minimal Model, a Pump Delivery to Plasma Insulin Model, and a Meal Appearance Rate Model.Type: ApplicationFiled: October 29, 2020Publication date: February 11, 2021Inventors: GARRY M. STEIL, SAMI S. KANDERIAN, JR., MARTIN T. CANTWELL, UDO HOSS
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Publication number: 20210038135Abstract: The present disclosure is directed to relates to systems and methods for evaluating tissue using high intensity focused ultrasound (HIFU) energy. In one embodiment, for example, a system for treating a patient comprises an ultrasound source configured to deliver HIFU energy to a target tissue mass of the patient and a function generator operably coupled to the ultrasound source for initiating a pulsing protocol for delivering the HIFU energy. The system further comprises a controller configured to perform operations comprising applying HIFU energy to induce cavitation in the target tissue mass and cause a biomarker to be released, comparing a baseline concentration of the biomarker from a first fluid sample to a concentration of the biomarker in a second fluid sample within 2 hours after applying HIFU, and repeating the applying and comparing until the concentration of the biomarker in the fluid sample falls below a threshold value.Type: ApplicationFiled: July 22, 2020Publication date: February 11, 2021Inventors: John R. Chevillet, Tatiana D. Khokhlova, George R. Schade, Joo Ha Hwang, Muneesh Tewari
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Publication number: 20210038136Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.Type: ApplicationFiled: October 21, 2020Publication date: February 11, 2021Applicant: DexCom, Inc.Inventors: Apurv Ullas Kamath, Jack Pryor, Paul V. Goode, JR., James H. Brauker, Aarthi Mahalingam
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Publication number: 20210038137Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.Type: ApplicationFiled: October 22, 2020Publication date: February 11, 2021Inventors: Samuel M. Curry, Manuel L. Donnay, Tuan Nguyen, Louis G. Pace, Peter G. Robinson, Phillip Yee
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Publication number: 20210038138Abstract: Methods, devices, systems and kits for obtaining blood samples are provided. Devices include a cuff, a pressure source, and a timing mechanism. Devices may further include one or more of a: warming mechanism, lancing mechanism; automated sample collection device, automated sample analysis device, and communication unit. Systems include such a device, and may include sample collection, sample analysis, or communication devices. Methods include placing a cuff on a digit of a subject, inflating the cuff, and obtaining a small volume blood sample. Methods may further include warming a digit; lancing a digit; pulsing the cuff; and providing a signal indicating the end of the sample collection time period. Kits may include a device, a sample collection vessel, and may include a disposable for use in sample collection. These methods, devices, systems and kits for obtaining blood samples may be used to easily, reliably, and consistently obtain blood samples from subjects.Type: ApplicationFiled: July 21, 2020Publication date: February 11, 2021Inventors: Patricia McHale, William Westrick