Abstract: Embodiments of a hybrid imaging sensor and methods for pixel sub-column data read from the within a pixel array.

Abstract: This invention is related to a dental retractor including a body part having a handle portion, a neck portion extending from the handle portion, and a mirror part having a micro mirror, which is detachably attached to an end of the neck portion, such that the projection can be inserted in to a hole formed at a surgical site to observe an inside the hole. According to the present invention, since the dental retractor has the mirror part for observing the interior of the oral cavity, the number of operations, the number of persons required for the operation and the working time are reduced and it is not necessary to separately use a dental mirror. In addition, since the dental retractor has a mirror such as a micro mirror at the head portion, a doctor or other practitioner/technician can use the other hand to perform a medical examination.

Abstract: Certain aspects relate to systems and techniques for an endoscopic system to access, visualize, and treat pathologies in various organs via natural orifices and lumens of various organs. In one aspect, the system includes an elongate shaft configured for insertion into a urinary tract of a patient. The elongate shaft can include a proximal section, a distal section, a tip portion, and a plurality of pull wires extending along the elongate shaft and terminating at the tip portion of the elongate shaft. The plurality of pull wires may include a first and second pull wire. The first pull wire may be configured to articulate each of the proximal section and the distal section in a first direction. The second pull wire may be configured to articulate the distal section in a second direction independently of the proximal section, the second direction being transverse to the first direction.

Abstract: The present technology relates to an image processing apparatus and an image processing method, and particularly to an image processing apparatus and an image processing method capable of suppressing an increase in a load on a subject and obtaining a captured image of the subject with higher image quality. An imaging unit reduces a light amount and performs a plurality of imagings of the fundus of the eye so as to generate a plurality of fundus images. A biological information alignment processing unit aligns the fundus images by using biological information of a subject. A super-resolution processing unit superimposes an aligned input image on a previous super-resolution result image so as to generate a new super-resolution result image. The super-resolution processing unit stores or outputs the super-resolution result image in a storage unit or from an output unit, and supplies the super-resolution result image to a super-resolution result image buffer so as to be stored.

Abstract: Methods, systems, and computer readable media for testing visual function using virtual mobility tests are disclosed. One system includes a processor and a memory. The system is configured for configuring a virtual mobility test for testing visual function of a user; generating the virtual mobility test; and analyzing a user's performance during the virtual mobility test for determining the visual function of the user based on user interaction with objects in the virtual mobility test and using data from body movement detection sensors.

Abstract: Disclosed herein are system and method for testing and analysis of visual acuity and changes using an acuity model, the acuity model generated based on one or more acuity chart design parameters and candidate acuity parameters calculated using the acuity test data of the subject, the acuity model comprising a chart-specific psychometric function determined using a family of multiple-optotype psychometric functions, and wherein the acuity model is configurable to estimate possibility of obtaining the acuity test data of the subject.

Abstract: Systems and methods for tracking eye movement during a diagnostic procedure include a retina imaging system configured to capture a first plurality of images of an eye and detect a presence of a fovea, an eye tracker configured to capture a second plurality of images of the eye and track a position and orientation of the eye; and a control processor configured to synchronize the first and second plurality of images, determine a time at which the fovea is detected in the first plurality of images, and determine one or more images from the second plurality of images to be classified as representative of fixation. The classified images are analyzed to determine eye fixation status during the diagnostic procedure based on eye tracking data.

Abstract: Systems and methods for tracking eye movement during a diagnostic procedure include an eye tracker capturing images of an eye, and a control processor configured to detect an eye position and orientation in each of the images, determine an eye fixation position and orientation relative to an optical axis of the eye tracker, estimate eye fixation parameters based at least in part on the determined eye fixation position and orientation, and track the eye position and orientation by analyzing the images to determine the eye position and orientation relative to the eye fixation parameters. The eye fixation parameters may comprise a reference position and orientation of the eye when fixated. A histogram is constructed of detected eye positions and orientations and analyzed to determine an eye fixation position and orientation.

Abstract: An imaging system may include a panoramic gonioscopic imaging apparatus that includes a disposable component configured to rest against a cornea of a patient, and an objective optical device configured to direct a continuous panoramic image of an entire circumference of an iridocorneal angle of the patient on an intermediate imaging plane, and a relay lens configured to direct the continuous panoramic image from the intermediate imaging plane to a sensor such that the sensor captures the entire circumference of the iridocorneal angle at once. The imaging system may also include a computing device in communication with the panoramic gonioscopic imaging apparatus, where the computing device configured to display an image of the entire circumference of the iridocorneal angle.

Abstract: Systems and methods for monitoring eye health. The systems and methods monitor eye health by measuring scleral strain by way of an implantable monitor, a wearable monitor configured in eyeglasses, or an external monitor using a portable tablet computing device. Certain embodiments of the strain monitor may be utilized to measure the strain on any surface to which it is attached, including, but not limited to, the skin of a patient or the surface of a structure such as a building or a bridge.

Abstract: A system and method for a non-contrast enhanced magnetic resonance imaging technique using a temporal maximum intensity projection reconstructed from multiple temporal subsets of data acquired the acquisition window. The method includes applying a radiofrequency pulse to the subject, waiting a quiescent interval, performing a radial acquisition with a golden-angle view angle increment over a duration corresponding to a cardiac cycle of the subject to generate acquisition data, reconstructing a plurality of images across a plurality of temporal phases from the acquisition data and generating a temporal maximum intensity projection image by tracking an intensity of each pixel across the plurality of images and selecting the pixel having a maximum intensity value across the plurality of images.

Abstract: A subcutaneous electrocardiography monitor configured for self-optimizing ECG data compression is provided. ECG waveform characteristics are rarely identical in patients with cardiac disease making this innovation crucial for the long-term data storage and analysis of complex cardiac rhythm disorders. The monitor includes a memory and a micro-controller operable to execute under a micro-programmable control and configured to: obtain a series of electrode voltage values; select one or more of a plurality of compression algorithms for compressing the electrode voltage series; apply one or more of the selected compression algorithms to the electrode voltage series; evaluate a degree of compression of the electrode voltage series achieved using the application of the selected algorithms; apply one or more of the compression algorithms to the compressed electrode voltage series upon the degree of compression not meeting a predefined threshold; and store the compressed electrode voltage series within the memory.

Abstract: Parametric model based computer implemented methods for determining the stiffness of a bone, systems for estimating h the stiffness of a bone in vivo, and methods for determining the stiffness of a bone. The computer implemented methods include determining a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f) and independently fitting a parametric mathematical model to Y(f) and to H(f), and using a first measure of conformity and a second measure of conformity of the collected data to determine accuracy and repeatability of measurements. The systems include a device for measuring the stiffness of the bone in vivo and a data analyzer to determine a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f).

Abstract: The present invention relates to a three-dimensional oral scanner. In particular, the present invention comprises: a case which can be drawn in and out of an oral cavity and has an opening formed in a manner such that the shape of the inside of the oral cavity (hereinafter, abbreviated as “image”) is introduced to the inside in the form of light through one end thereof; a pair of lenses disposed inside the case and spaced apart from each other in the width direction of the case so as to pass light incident from one end of the case in different paths; a pair of imaging boards having an imaging sensor for imaging the respective lights transmitted through the pair of lenses and disposed in close contact with a widthwise side wall and the other widthwise side wall of the case; and a pair of light path changing units arranged to change the respective paths of the lights transmitted through the pair of lenses toward the imaging board.

Abstract: A cap for a thermometer having a probe configured to be placed in contact with a patients body or to be inserted into a body cavity of the patient and a temperature sensor includes a cap housing, a proximity sensor and a proximity sensor electrical conductor. The cap housing is configured to selectively connect with and to be selectively detached from the thermometer and at least partially surround the probe of the thermometer when connected with the thermometer. The proximity sensor is connected with the cap. The proximity sensor electrical conductor is connected with the cap and electrically connected with the proximity sensor. A thermometer including the cap is also provided.

Abstract: A blood pump including a housing having an inlet element, the inlet element including a distal portion coupled to the housing and a proximal portion sized to be received within at least a portion of a heart of a patient and a rotor configured to rotate within the housing and impel blood from the heart. At least one pressure sensor is coupled to the proximal portion of the inlet element.

Abstract: A method and device for analysis of sampled physiological parameters according to at least a second-order process over time, e.g., second-order differential equation or model, for use in therapeutic, diagnostic, or predictive health applications. The system may generate an alert regarding a present or predicted health abnormality. The biometric device may be implantable, wearable, contact or non-contact, and may communicate through a network, to send an alert. The system may further comprise an actuator or therapeutic device to perform an action based on the at least second-order process.

Abstract: A patient monitoring system to help manage a patient that is at risk of falling is disclosed. The system includes a patient-worn wireless sensor that senses the patient's motion and wirelessly transmits information indicative of the sensed motion to a patient monitor. The patient monitor receives, stores, and processes the transmitted information to determine whether the patient has fallen or is about to fall. Upon such detection, the system can notify the patient's caretakers that the patient has fallen or is about to fall and therefore, is in need of immediate attention.

Abstract: An adapter includes a substantially rigid body having a distal portion, a proximal portion, a central opening formed at least in part by an inner wall of the body, and a longitudinal axis extending substantially centrally through the opening. The distal portion includes an annular ring having a top surface and a ridge disposed opposite the top surface, the ridge extending substantially perpendicular to the longitudinal axis. The distal. The adapter also includes a seal configured to form a substantially fluid-tight seal with a surface of a fitting removably attachable to the adapter.

Abstract: A novel, modified MEMS accelerometer with additional ability to measure optical radiation due to integration of silicon photodiode in the silicon cap. The silicon cap is used to protect the MEMS based accelerometer from the environment. The function of the cap is enhanced to include optical measurement. The entire sensor element including accelerometer and photodiode (XL+PD) occupies no more space than the XL alone.

Abstract: A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal tip, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position spaced from the distal tip of the sheath. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a straight configuration to a dual hinged curved configuration that positions the electrodes in the vicinity of the bundle of His.

Abstract: A brain mapping system and methods for providing personalized therapy for a broad range of brain dysfunctions by determining the location and the extent of the brain regions that have to be therapeutically targeted in each subject. The present invention includes means to record specific characteristics of brain activity, detect and display brain regions that present signatures of disease or dysfunctions by using a computing system. The therapy is tuned to target detected brain regions to restore specific connectivity characteristics using invasive, non-invasive stimulation, neurofeedback or drug administration. While connectivity characteristics are estimated based on resting state recordings the therapy will be performed in successive steps to alter network fragmentation in dysfunctional brain regions.

Abstract: The present disclosure relates to identification of focal areas of abnormal interactions in a brain of an anesthetized subject. During the maintenance period of anesthesia and/or the post-emergence period of anesthesia, neurophysiological time series signals from two or more areas of the brain of the subject can be recorded. A system that includes a processor can receive these signals, estimate a percentage of time (POT) each of the two or more areas of the brain of the subject exhibits a maximum total effective inflow (TEI) of information, and localize one or more focal areas of abnormal brain interactions based on the POT of each of the at least two areas exhibiting maximum TEI.

Abstract: A system and method for cardiovascular monitoring and reporting are disclosed. The system (CV monitoring system) includes a data analysis system and an in-ear biosensor system that preferably includes left and right earbuds. The earbuds include infrasound/vibration sensors that detect biosignals from the individual including signals associated with cardiovascular activity (CV signals). The analysis system calculates cardiovascular function measurements (CV function measurements) based upon the CV signals. The CV monitoring system uses machine learning to predict blood pressure (BP) measurements of the individual based upon the CV signals and the calculated CV function measurements. In an embodiment, the CV monitoring system includes an EKG detection system that detects EKG signals associated with heart function.

Abstract: Methods, apparatus, and systems for medical procedures are disclosed herein and include sensing a plurality of tissue electrical potentials at an organ area of an organ, by one or more electrodes on a catheter, determining a number of peak electrical potentials from the plurality of first tissue electrical potentials such that the a peak electrical potential exceeds a potential threshold, determining a first visual characteristic based on the number of peak electrical potential and displaying a rendering of the organ comprising the organ area such that the rendering of the first organ area comprises the first visual characteristic.

Abstract: The present invention relates to a system and methods generally aimed at surgery. More particularly, the present invention is directed at a system and related methods for performing surgical procedures and assessments involving the use of neurophysiology.

Abstract: Disclosed herein are embodiments for a standing equine magnetic resonance imaging device. The device includes two opposing planar power transmit coils facing each other. Each of the planar power transmit coils includes a plurality of radio frequency conducting planar rungs arranged to form concentric circles and a plurality of radio frequency conducting planar spokes extending from an outermost rung and connecting to each of the rung circles. At least one pin diode is positioned across the outermost rung circle. A plurality of tuning capacitors are positioned across the spokes.

Abstract: Embodiments of this disclosure provide an apparatus and method for detecting a living body. The apparatus is to obtain range FFT signals within a first time range according to reflected signals of a microwave radar within the first time range; obtain amplitude distributions and/or phase distributions of distances in the first time range according to the range FFT signals within the first time range, and calculate amplitude fluctuations of the distances within the first time range. A Fourier transform is performed on the amplitude distributions and/or the phase distributions to obtain amplitude spectra and/or phase spectra; and based on magnitudes of the amplitude fluctuations, it may be determined whether there exists a living body corresponding to the distances according to the amplitude spectra and/or the phase spectra, and the amplitude fluctuations, or it may be determined whether there exists a living body corresponding to the distances according to the amplitude spectra and/or the phase spectra.

Abstract: It is disclosed a device for microwave measurement of a dielectric discontinuity of a material to be inspected. The device comprises a launcher for waveguide, a waveguide and a receiving antenna. The launcher is configured to emit in the waveguide a microwave electromagnetic field adapted to interact with the material to be inspected. The receiving antenna is configured to receive a electromagnetic field reflected by the material to be inspected. The waveguide is configured to propagate the emitted electromagnetic field towards the material to be inspected and to convey the reflected electromagnetic field towards the receiving antenna. The waveguide has an inspection seat configured for the insertion of at least one portion of the material. At least one of either the launcher or the receiving antenna is movable in a plurality of positions around the inspection seat.

Abstract: A screen providing a GUI is disclosed for a tissue biopsy system having a tissue cutting member. The screen includes a first GUI area configured to represent a first region of the target site from which at least one tissue specimen has been separated from tissue at the target site by the tissue cutting member. The screen further includes a second GUI area configured to represent a second region from which the tissue cutting member may separate one or more additional tissue specimens from tissue at the target site. The screen includes a third GUI area configured to represent a third region in which the tissue cutting member is deployed to separate a tissue specimen from tissue at the target site. The GUI is configured to update the first GUI area, the second GUI area, and the third GUI area as the tissue cutting member is rotated within the patient.

Abstract: A measurement apparatus (1, 2, 3, 71), a measurement method and an electronic device (7) for measuring the energy expenditure of an individual. The measurement apparatus (1, 2, 3, 71) comprises: a near-infrared unit (10) for emitting near-infrared rays to muscle tissue of an individual, so as to determine muscle oxygenation value of the individual by reflection of the near-infrared rays by the muscle tissue; an electrode array (20) for measuring conductivity of skin of the individual; and a control unit (30) operably connected to the near-infrared unit (10) and the electrode array (20), to control activation of the near-infrared unit (10) and the electrode array (20), and to obtain muscle oxygenation value and conductivity, so as to determine energy expenditure of the individual based on muscle oxygenation value and conductivity and skin temperature of the individual and ambient temperature.

Abstract: A capnograph system may be used together with a ventilation system for a patient. The capnograph system may include a capnography module with a carbon dioxide detector, which may generate a carbon dioxide signal responsive to an amount of carbon dioxide detected within an air path of the ventilation system. A monitoring circuit may further detect a pressure within the air path. A processing component within the capnography module may generate a pressure signal responsive to the pressure detected in the air path. The pressure signal, alone or in combination with other signals such as the carbon dioxide signal, may be used to detect spontaneous breaths of the patient.

Abstract: In particular embodiments, a method includes accessing, by a computing device, sensor data from a sensor of a client device corresponding to a user. The method further includes determining one or more segments of sensor data and selecting at least one segment of sensor data. The method further concludes determining, based at least on the selected segments of sensor data, one or more features corresponding to the user's pulmonary condition. The method further includes determining, based at least on the determined features, an assessment of the user's pulmonary condition.

Abstract: A device and method for measuring respiratory air flow of a subject are provided. The device includes a hollow member having a proximal end, a distal end and a flow passage formed between the proximal and distal ends. The proximal end is configured to be received in a mouth of a subject. A flow sensor, such as thermal mass flow sensor, is disposed in the flow passage and configured to sense characteristics of an air flow in the flow passage. A processor is communicatively coupled to the flow sensor and configured to determine, based on an output from the flow sensor, whether the sensed characteristics of the air flow correspond to predetermined parameters.

Abstract: Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.

Abstract: An apparatus and computerized method of classifying a patient that has been previously diagnosed to have autosomal dominant polycystic kidney disease (ADPKD) includes providing a computing device having an input/output interface, one or more processors and a memory; receiving a total kidney volume (TKV), a patient height, and a patient age for the patient via the input/output interface; determining a height adjusted TKV (HtTKV) based on the total kidney volume and the patient height using the one or more processors; determining an ADPKD classification for the patient based on the height adjusted TKV and the patient age using the one or more processors; and providing the ADPKD classification for the patient via the input/output interface.

Abstract: A wearable device for monitoring physiological changes in a patient is provided. The device can include a housing adapted to being secured to a patient's body, the housing comprising a needle configured for fluid contact with a bodily fluid under a skin surface; a chamber having a cell layer and configured to monitor physiological changes in the bodily fluid and to generate one or more signals associated with the physiological changes; and a reader for detecting and/or decoding signals from the cell layer to monitor physiological changes in the patient. The device is capable of engaging in a two-way communication with a second device through transmission of one or more signals.

Abstract: An on-body insertion system is described. The on-body system includes a sensor in a first position being substantially parallel to an insertion surface. Activation of an actuator transitions the sensor to a second position. Wherein the transition imparts movement to the sensor that is substantially parallel to the insertion surface and the second position results in the sensing area being beneath the insertion surface.

Abstract: The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present disclosure relates to an electrode system for measuring the concentration of an analyte under in-vivo conditions, comprising an electrode with immobilized enzyme molecules and a diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: A wearable optical device is described for optically detecting parameters of interest within muscle, such as during physical activity or when at rest. The parameters of interest include oxygenation level and/or hemoglobin concentrations in some situations. The detected parameters, such as oxygenation level, may be used to assess physical performance, such as the extent to which the muscle is utilizing aerobic or anaerobic processes. Methods for determining the parameters of interest, such as oxygenation level, from the detected optical signals are also described, and feedback may be provided to a user.

Abstract: Disclosed herein are methods and systems for capillary oximetry (e.g., retinal capillary oximetry) using optical coherence tomography (OCT). The method may include obtaining an OCT angiography dataset, performing capillary segmentation based on the OCT angiography dataset to obtain capillary segments, resampling, registering, and/or averaging B-scans of the OCT angiography dataset that correspond to a first capillary segment of the capillary segments to obtain an averaged B-scan for the first capillary segment, determining an anterior and posterior border of the first capillary segment, and determining an oxygen saturation of the first capillary segment based on the averaged B-scan, the anterior border, and the posterior border. Other embodiments may be described and claimed.

Abstract: An estimation system includes: a first sensor that detects a first amount of activity that is an amount of activity of a subject in a room; a second sensor that detects a second amount of activity that is an amount of activity of the subject on a bed in the room; and an estimation device that estimates at least one of a position and an action of the subject in association with a position in the room based on the first amount of activity detected by the first sensor and the second amount of activity detected by the second sensor, and outputs an estimation result obtained from the estimation. The first sensor and the second sensor are sensors other than two-dimensional image sensors.