Abstract: Method and systems are provided for reliable, convenient, self-administered, and cost-effective determination of central venous pressure. The noninvasive method and apparatus use changes in transmural pressure to create detectable changes in peripheral venous vascular volume for the determination of central venous pressure. Transmural pressure changes can be manifested by intravascular or extravascular pressure changes. The system is noninvasive and uses optical measurements of venous volume in the presence of transmural pressure changes. The relationship between the transmural pressure change and the change in vascular venous volume is combined with anatomical measurements to determine the central venous pressure of the subject. Central venous pressure can be used to determine hemodynamic status of the subject to include fluid overload in the heart failure patient.

Abstract: A portable spot-check system configured to assess the validity of a measured physiological parameter. The spot-check device can take into consideration a variety of factors to determine whether a valid measurement exists. For instance, the considerations can include signal stability, interference, signal IQ, patient movement, sensor position, timing of that measurement, comparison to previous or acceptable measurements, cancellation of measurement by the patient, confidence of the measurement, etc. The spot-check device can track a number of valid measurements. In some instances, the spot-check device is configured to provide a specified number of available measurements. If a valid measurement is recorded, the spot-check device can decrement the remaining number of available measurements.

Abstract: Methods, apparatus, and systems for medical procedures are disclosed herein and include detecting points of an intra-cardiac area that exhibits abnormal activations, such as local abnormal ventricular activations (LAVAs). Points that exhibit such abnormal activations may be referred to as seed points that are identified during a first step of the process disclosed herein. The seed points may be identified using one or more inputs such as unipolar and bipolar mapping channels, body surface ECGs, past activations, neighboring points and the like during the first step which prioritizes high specificity over sensitivity. During a second step which prioritizes high sensitivity, electrical activations of neighboring points near the seed points are analyzed to determine if the activations are similar (e.g., have a similar time) as the abnormal activations corresponding to the corresponding seed points.

Abstract: An electromyography (EMG) device according to an aspect of the present disclosure includes a main circuit board having opposing first and second faces. A plurality of first connectors of a first type are provided on the first face, and a plurality of input contacts are provided on the second face. An EMG circuit is provided on the main circuit board. The EMG circuit is configured to utilize the input contacts as inputs to obtain an EMG input signal, and process the EMG input signal to provide an EMG output signal that is based on, but different from, the EMG input signal. For each of the input contacts, there is no conductive path directly between the input contact and any of the first connectors.

Abstract: A system for generating an indicator at least in part relating to fluid levels in a biological subject, the system including one or more processing devices that, in response to at least one impedance measurement performed on the subject determine a parameter value at least in part using results of the at least one impedance measurement, perform an assessment to determine if the parameter value is indicative of a meaningful change in a subject normal, the subject normal being based on results of a plurality of previous impedance measurements and use results of the assessment to generate an indicator indicative of fluid levels or selectively update the subject normal.

Abstract: A system is provided for determining the position of an implanted device (10) in a human or animal body relative to a probe (12). In one device, a reference signal is generated and it is received in the other device. A phase angle or an amplitude attenuation or difference between the reference signal and the received signal is used to determine the proximity the probe to the implanted device. The approach makes use of body channel sensing by which the frequencies at which the body behaves as a waveguide are employed.

Abstract: A surgical tool having an electromagnetic (EM) sensor component is provided. The surgical tool has a flexible shaft portion. Additionally, the surgical tool has a rigid portion attached to the flexible shaft portion. The rigid portion comprises at least one EM sensor within the rigid portion. The at least one EM sensor comprises an extended core portion surrounded by a coil. Additionally, the at least one EM sensor generates a change in voltage when exposed to an electromagnetic field.

Abstract: Among other things, sound records captured from a subject by auscultation at sound capture points on the subject are classified among sound classes. Respiratory conditions can be inferred from the sound records and other information. Information about the respiratory conditions can be presented to the subject or to a healthcare provider for purposes of managing the respiratory conditions.

Abstract: A method for analyzing forced expiration is disclosed. The method comprises receiving forced expiration flow-volume data collected by a spirometer; fitting a second order differential equation in volume to the forced expiration flow-volume data; and determining a parameter representative of airway resistance in dependence upon a coefficient of a first order term in the differential equation.

Abstract: The systems and methods provide for novel a triggering mode that allows the patient to trigger or initiate the delivery of a breath during ventilation on a ventilator. Further, the systems and methods provide for triggering ventilation utilizing a statistical trigger mode. Additionally, the systems and methods provide for analyzing and/or displaying information related to a potential change in a triggering threshold for a currently utilized breath type.

Abstract: A physiological monitoring method and device, the device comprising: a fixation band adapted to be fastened around a user's torso; a monitoring assembly fastened to the fixation band, the monitoring assembly comprising: at least one deformable member adapted to be deformed in response to an expansion of the user's torso; at least one deformation sensor operatively connected to the at least one deformable member for measuring a deformation of the deformable member; a processing unit operatively connected to the at least one sensor for determining a physiological parameter value of the user based on the measured deformation.

Abstract: A method and system for monitoring oxygen saturation of a patient are provided. An example system includes a wearable device having a first optical sensor to measure a first red wavelength photoplethysmography (PPG) signal and a first infrared wavelength PPG signal and a second optical sensor to measure a second red wavelength PPG signal and a second infrared wavelength PPG signal. The system further includes a processor configured to determine that conditions for calibration of the first optical sensor are satisfied, determine a first ratio for obtaining the oxygen saturation, a first parameter for modifying the first red wavelength PPG signal, a second parameter for modifying the first infrared wavelength PPG signal, and a second ratio for obtaining the oxygen saturation. The processor is further configured to determine a value of the oxygen saturation and provide a message regarding a health status of the patient.

Abstract: Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.

Abstract: A non-invasive device for holding one or more respiratory sensors includes a housing anatomically shaped to be attached to a subject's face in proximity to the respiratory orifices, and including one or more flow directing elements for directing at least a portion of the respiratory flow to one or more locations in the housing configured to hold at least one sensor.

Abstract: An apparatus for collecting volatile organic compounds from a gas sample such as alveolar breath or room air comprises an exhaust portion having at least a flow measuring device, and a discriminating device for distinguishing between alveolar and non-alveolar breath. The apparatus further comprises a collection portion distinct from and parallel with the exhaust portion having at least a collection component for receiving and concentrating gas samples within a collection chamber and a sampling component having a plurality of sampling devices for receiving the concentrated gas sample from the collection chamber and isolating VOCs contained in the gas sample. The collection chamber is compressible via a drive mechanism for precisely actuating the chamber to draw a gas sample into the collection chamber and circulating the sample to the sampling devices. Use of a drive mechanism enables the exhaust portion to be distinct from the collection portion, thereby mitigating cross-contamination therebetween.

Abstract: Disclosed herein is a gait analysis apparatus that is configured to provide multidimensional measures of the gait of an individual as the individual traverses the gait analysis apparatus. The gait analysis apparatus may be configured to provide a gait measuring processing device with the multidimensional measurements. Based on the multidimensional measurements, the gait measuring process device may, for example, diagnose the test subject with lameness or particular neuromuscular dysfunctions (NM) disease and/or injury, monitor progression of lameness or a particular NM disease and/or injury over time, determine a static weight as the test subject is traversing, monitor the static weight of the test subject over an extended period time, and/or determine which measurements may be used as biomarkers to identify lameness or the particular NM disease and/or injury. A system including a gait analysis apparatus is also disclosed.

Abstract: A foot pressure measurement apparatus, method, and non-transitory tangible machine-readable medium thereof are provided. The foot pressure measurement apparatus stores multiple first pressure value sets corresponding to a first position set of a foot and multiple second pressure value sets corresponding to a second position set of the foot. A first position quantity of the first position set is smaller than a second position quantity of the second position set. The foot pressure measurement apparatus decides multiple candidate weight set. For each candidate set, the foot pressure measurement apparatus calculates multiple first center of pressure (COP) values and multiple second COP values and calculates an accumulated difference corresponding to the candidate weight set according to the first COP values and the second COP values. The foot pressure measurement apparatus further determines a designated weight set from the candidate weight sets according to the accumulated differences.

Abstract: Dental caliper and method for determining occlusion. The caliper may comprise an elongate member, or “beam”, marked with a scale (indicia); a first jaw (or probe) extending from the beam, and fixed to the beam; and a second jaw (or probe) extending from the beam, and movable along the beam; wherein: a proximal portion of the first (fixed) jaw is offset from a distal portion of the jaw. The offset may be is fixed, such as 3 mm, or may have a gradient, such as 3-5 mm. The method may comprise using the caliper to (i) measure the eye-to-ear distance and (ii) measure the nose-to-chin distance. This may be done without adjusting the probes. The caliper and method of use may represent an improvement over U.S. Pat. No. 4,718,850 (Knebelman).

Abstract: A system for monitoring patient movement during a medical procedure requiring minimal movements, comprising a wireless sensor module responsive to movement incorporating a microprocessor and executable computer code stored in memory and an inertial measurement unit connected to the microprocessor sensitive to angular pitch changes and attached to a patient. A patient movement monitor incorporating a microprocessor and executable computer code stored in memory and a display displaying processed patient movement data including visual data graphically depicting movement within one or more movement parameters required to execute the medical procedure and visible to the patient during the medical procedure interfaced with the wireless sensor module. A sensor control and monitoring unit incorporating a microprocessor and executable computer code stored in memory and a display in wireless communication with the wireless sensor module.

Abstract: The invention relates to a system 1 of characterizing the gait of a user to obtain a value representative of the evolution of the gait of said user, including a pair 10 of soles, the soles 11, 12, constituting said pair 10 of soles, each including an electronic box 100, 101, 102, each electronic box 100, 101, 102 comprising: an inertial platform 110, 111, 112, a data processing module 120, 121, 122, a data storage module 130, 131, 132, and a power source 160, 161, 162; said system including a data comparison module 140, 141, 142 configured to compare the at least one biomechanical parameter to reference biomechanical parameters and calculate a value representative of the evolution of the gait of the user; said data comparison module being carried by the electronic boxes or the external terminal; and each electronic box including a first communication means.

Abstract: Embodiments of the present invention disclose a method for fall detection and protection, which is configured to apply in a wearable device worn on a human body, the method comprising: obtaining a gesture variation information of chest or abdomen of the human body from the wearable device; determining whether the human body is in a dynamic state depending on the gesture variation information; if the human body is in a dynamic state, obtaining a gesture information of chest and abdomen of the human body at the present moment and determining if the human body is in a state of being about to fall; if the human body is in a state of being about to fall, determining whether the fall is an unconscious fall; and if the fall is an unconscious fall, protecting the human body. Embodiments of the present invention can accurately determine an unconscious fall and provide protection that can prevents injury.

Abstract: An animal physical activity tracking device is adapted for contacting with a skin of an animal. The device comprises a substrate for contacting the skin, a sensing module disposed on the substrate, a communication module disposed on the substrate and a control module disposed on the substrate. The sensing module comprises a skin sensing module for sensing the skin to generate a dermatoglyphic signal, and a physiological sensing module for sensing the animal to generate a physiological signal. The control module outputs the dermatoglyphic signal and physiological signal through the communication module.

Abstract: The present disclosure relates to systems and processes for monitoring a workout and for generating improved interfaces for the same. One example user interface detects when a workout of a particular type is started and begins generating activity data related to workout metrics associated with the type of workout selected. Using determined current values for the workout metrics, the example user interface displays a pro-view display that includes indicators for the workout metrics associated with the selected workout type. The pro-view display also includes a focus indicator that highlights a selected indicator representative of a focused workout metric. The focus indicator is movable among the indicators representative of the workout metrics based on user input. Upon detection of a gesture, the example user interface transitions to a simple-view display that includes an indicator representative of the focused workout metric.

Abstract: A joint bending state determining device comprises a sensor group and a processor. The sensor group comprises first and second gravity sensors. The first/second gravity sensor generates a first/second polar angle and a first/second azimuth angle. The processor obtains a first length corresponding to the first gravity sensor and a second length corresponding to the second gravity sensor, obtains a set of coordinates of a joint in a coordinate system according to the first polar angle, the first azimuth angle and the first length, obtains a set of coordinates of the second gravity sensor in the coordinate system according to the set of coordinates of the joint, the second polar angle, the second azimuth angle and the second length, and obtains a joint angle according to the set of coordinates of the second gravity sensor in the coordinate system, the first length and the second length.

Abstract: A system and method for capturing and analyzing a person's behavioral functions (e.g., 3-D bodily movements, facial expressions, vocalizations), and for developing a corresponding personal behavioral signature. The capture may be performed passively, e.g., in contactless manner (e.g., using LIDAR or camera-based imaging, and/or a microphone). Artificial intelligence, machine learning, and/or other techniques to may be used to analyze captured behavioral function data to identify patterns, assess characteristics, etc., and develop the corresponding behavioral signature. A baseline signature may be compared to a subsequent signature to assess a change in behavioral state. Similarly, data and/or signatures for multiple individuals having a common disease (or receiving a common treatment) may be analyzed to develop a characteristic disease signature (or treatment signature).

Abstract: A fingerprint reading device that can suppress a position shift of a finger, that includes: a placement portion on which a finger is placed; a reading face; a pair of light sources provided on the placement portion and that irradiate the finger with lights; and a reading unit that captures and reads a fingerprint of the finger in contact with the reading face in accordance with lights scattered in the finger and emitted from a surface of the finger, the pair of light sources are provided on both ends of the reading face that are opposed to each other in a width direction of the placement portion and have light guiding parts formed in a front-back direction of the placement portion, respectively, and the light guiding parts are formed so as to extend up to above the ends of the reading face.

Abstract: Embodiments are disclosed for a method for restoring a wearable biological sensor. The method includes determining that a wearable biological marker sensor comprising a reference electrode is placed within a restoration apparatus. The restoration apparatus includes a correct reference electrode, a counter electrode, and a chloride solution. The reference electrode is in electrical contact with the correct reference electrode and the counter electrode through the chloride solution. The method additionally includes determining whether the reference electrode is degraded based on a voltage differential between the reference electrode and the correct reference electrode. The method also includes restoring the reference electrode, if the reference electrode is degraded, by applying a voltage to a circuit. The circuit includes the reference electrode and the counter electrode. Further, multiple chloride ions of the chloride solution bond with a plurality of silver atoms of the reference electrode.

Abstract: The present disclosure relates to a dialysis device (1), more particularly a microdialysis device for the sampling of substances from the surface of a body organ. The device is particularly useful in the context of the monitoring of a moving organ, such as a beating heart, as the device comprises attachment means (2) allowing for a flexible and reliable attachment thereto. Furthermore, the microdialysis device provides for an efficient exchange of substances, such as metabolic substances, between the organ and the dialysis fluid through a semi-permeable material forming part of the device. There is also provided a method encompassing the device of the disclosure.

Abstract: Biosensing platform deployed in a catheter is described which permits long-term operation of biosensors monitoring glucose and other analytes subcutaneously or intraperitoneally (IP) to manage diabetes. A method for integrating a plurality of biosensors monitoring glucose and other analytes into a catheter platform. The catheter platform comprises of electrochemical sensors, sensor electronics, RF and optical communication devices, as well as pump control electronics to facilitate glucose management. Catheter mounted biosensor is shown with micro-dialysis provisions.

Abstract: Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: A wearable member may include a plurality of energy transmitters that are arranged on a surface of the wearable member, each of the energy transmitters being configured to project energy into tissue of a user. A wearable member may include a plurality of energy receivers each of which is configured to generate a signal based on a received portion of the energy that is projected by one or more of the energy transmitters and reflected by the tissue of the user, wherein at least one of the energy transmitters and the energy receivers are multi-dimensionally arranged on the wearable member such that energy reflected by the tissue of the user at locations that are multi-dimensionally different is incident on the plurality of energy receivers. The processor may be configured to calculate a biological metric based on signals generated by at least part of the plurality of energy receivers.

Abstract: A solid film structure formed of multiple solid film insert layers each having different functionality is provided. The solid film structure forms a bio-chemotronic structure having an actuator thin film layer with one or more low molecular weight organic active agents that may be activated, a sensor thin film layer that includes one or more sensors for measuring a direct or indirect response from a target to the one or more active agents, and a control thin film layer configured to individually control activation of the active agents in the actuator layer, e.g., according to a protocol.

Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

Abstract: An Internet of Things (IOT) system for management of a stress level and mental health of a human body. The system has one or more body sensors and a primary processing unit that runs an artificial intelligence system. The body sensors are adapted to measure at least one of a physiological parameter of the human body, body movement of the human body, or heat expenditure of the human body or combination thereof, and to generate a body data periodically or in realtime. The primary processing unit is adapted to receive and process the body data and adapted to determine at least one of the mental health of the human body and the stress level of the human body. The primary processing unit is adapted to provide therapies and give insights about the effectiveness of psychological therapies including CBD, meditation and mindfulness in a quantitative manner.

Abstract: A method, system, and computer program product for limiting the amount of electromagnetic frequency emissions from a mobile device in a time of high anxiety. The method may include determining whether a user is awaiting a first notification on a mobile device. The method may also include estimating an anxiety level of the user based on the determining. The method may also include determining whether the anxiety level is above a threshold anxiety level. The method may also include calculating, in response to determining that the anxiety level is above the threshold anxiety level, a ping-pong rate for the mobile device. The method may also include reducing the ping-pong rate.

Abstract: [Problem] To provide an information processing system, an information processing method, and a recording medium capable of making a state of a user better according to an emotion of the user and improving quality of life. [Solution] The information processing system includes a control unit that estimates whether a user is positive or negative and has any one of a function of promoting an action of the user when it is estimated that the user is positive, a function of suppressing an action of the user when it is estimated that the user is negative, or a function of presenting a positive interpretation on a situation or action of the user when it is estimated that the user is negative.

Abstract: A needle electrode fixation device is configured to secure a transdermal needle electrode to a patient. The device includes a base having a body that defines a first portion and a second portion. The first and second portions are rotatable relative to each other. The first portion defines a channel configured to fit a portion of the transdermal needle electrode. The second portion defines a recess configured to fit a tip of the needle electrode. The device further includes an adhesive layer configured to affix the base to the patient.

Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods include evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

Abstract: Described herein are methods, software, systems and devices for detecting the presence of an abnormality in an organ, tissue, body, or portion thereof of a subject by analysis of the electromagnetic fields generated by the organ, tissue, body, or portion thereof.

Abstract: The signal quality of an electrophysiological signal can be determined from information regarding proximal stability of an electrophysiology catheter at the time the signal is acquired and temporal stability of the electrophysiological signal. The proximal stability information can include a distance between the electrophysiology catheter and an anatomical surface, a velocity of the electrophysiology catheter, and/or contact force between the electrophysiology catheter and the anatomical surface. Graphical representations of signal quality scores can be output to a display in order to enable visualization thereof by a practitioner.

Abstract: It is provided an electrode extension assembly comprising: a fastener for releasably fastening the electrode extension assembly to a user; a device holder for releasably holding a portable sensor device configured to capture electrocardiogram signals and audio signals; at least two extenders extending radially outwards from the device holder, wherein each extender comprises: a connector configured to connect to a respective electrode of the portable sensor device; an outer electrode connected at a distal end of the extender, the outer electrode being configured to be applied to a user; a conductor connected on one end to the connector and on the other end to the outer electrode; and an audio signal conveyor for conveying audio signals from the user to an audio sensor of the portable sensor device.

Abstract: In accordance with some embodiments of the disclosed subject matter, mechanisms for efficient real-time embedded processing of physiological signals using S transforms are provided. In some embodiments, a system comprises: a sensor configured to monitor at least one condition of the subject and generate physiological feedback data; a processor configured to receive the physiological feedback data from the sensor and programmed to: implement a ECG Leads filter bank with a predetermined number of coefficients and taps selected to perform a Stockwell transform on the physiological feedback data and provide a frequency domain data of the physiological feedback data; analyze the frequency domain data using a physiological monitoring criteria; generate a report about the physiological condition of the subject based on the analysis of the frequency domain data using the physiological monitoring criteria; a display configured to display the report about the physiological condition of the subject.

Abstract: A device and a signal processing method that can monitor human memory performance by recognizing and characterizing high-gamma (65-250 Hz) and beta (14-30 Hz) band oscillations in the left Brodmann Area 40 (BA40) of the brain that correspond with the strength of memory encoding or correct recall. The signal processing method detects high-gamma and beta band oscillations in the electrical signals recorded from left BA40, and quantifies the spectral content, power, duration, onset, and offset of the oscillations. The oscillation's properties are used to classify the subject's memory performance on the basis of a comparison with the subject's prior human memory performance and the properties of the corresponding oscillations. A report of the subject's current memory performance can be utilized in a closed loop brain stimulation device that serves the purpose of enhancing human memory performance.

Abstract: Disclosed are compositions and methods for measuring olfactory sensitivity, olfactory resolution, and combinations thereof. Such measurements can be made during a single test, or over consecutive tests, which may be performed during a single testing period, such as in a single day, or over a series of testing periods. The tests may be performed by a health care professional, or may be conveniently self-administered by the user.