Abstract: Wearable devices that track activity and ventilation rates for use on humans or animals that breathe air and methods of use thereof, are provided. The device is generally suitable to be worn around a subject's chest, and typically contains one or more sensors. Generally, one sensor detects respiratory rate and another sensor detects acceleration (i.e. activity). The method and apparatus can be used to determine the minimum ventilation rate for a given degree (intensity) of movement to construct the ‘stress-free’ relationship between ventilation rate and movement. Then measured values of ventilation rate in relation to movement are compared to the predicted, minimum ventilation rates (stress-free values) and the minimum ‘stress-free’ values are subtracted from the measured values. The difference (Ventilation Rate Above Predicted’ (VRAP)) correlates with stress in the subject.

Abstract: A method for determining a membership function, the membership functions allowing a stress level of a user to be determined on the basis of a physiological parameter measured on the user, the membership function varying, depending on the physiological parameter, between: a first value, representative of a rest state; and a second value, representative of a stressed state; the membership function taking into account a distribution function, which is defined beforehand, the distribution function being a continuous and monotonic function, the distribution function being applied to a normalized parameter established on the basis of a measured physiological parameter, the method comprising determining a normalization function, and optionally a standardization function, the normalization function and the optional standardization function being determined on the basis of physiological parameters measured on a plurality of test individuals, in various calibration periods.

Abstract: Brain activity of a user is detected, and a mental state of the user is determined. In one technique, life/work context is automatically presented to the user in a manner that modulates the mental state of the user. In another technique, an entertainment selection is presented to the user, and an entertainment selection list is automatically modified in response to the determined mental state of the user. In still another technique, the mental state that is determined is a negative emotional state, and life/work context is automatically presented to the user in a manner that promotes a cognitive state of the user in response to the determined emotional state of the user. In yet another technique, the wellness of the user is automatically tracked over a time period based on the determined mental state.

Abstract: An apparatus for determining a cognitive state of a user of a mobile device (2) of the apparatus (1), the apparatus (1) comprising: an output means (5) in the mobile device (2) for giving out information to the user, wherein the output means (5) comprises an optical output means (5.1) for optically giving out information to the user; a camera (3) in the mobile device (2) for recording images in a first view direction (3.1) of an environment of the mobile device (2); a path means (6) configured to determine a positional path of the mobile device (2) in the environment; a further camera (4) in the mobile device (10) for recording images in a second view direction (4.1) and/or a microphone (13) for recording an audio signal; a task means (7, 7?) for interacting via the output means (5) with the user to make the user solve a task using an augmented reality environment shown via the optical output means (5.

Abstract: A method and a system are provided for taking biomarker measurements of patients who have ADHD. Mathematical analysis (e.g., pattern recognition, machine learning and AI algorithms) of the biomarker measurements is used to create a unique personal prediction model and data set for an individual patient. The unique personal data set is used to diagnose and monitor a particular problem of the individual patient associated with ADHD, or to recommend a treatment for a particular problem of the individual patient associated with ADHD, or to predict an outcome of a treatment for a particular problem of the individual patient associated with ADHD.

Abstract: This document describes methods for assessing defecatory disorders of patients. For example, this document describes methods for assessing evacuation using seated manometry and methods for analyzing rectoanal pressures to diagnose pelvic floor dysfunction.

Abstract: A magnetoencephalography apparatus includes: a lead configured to be secured to a user's head; a first magnetic field sensor attached to the lead, the first magnetic field sensor including a substrate, and an electron spin defect layer on the substrate, the electron spin defect layer including at least one lattice defect, in which a first spin energy level of the at least one lattice defect splits upon exposure to a microwave; and cabling, in which the cabling includes a first microwave transmission line arranged to provide a first microwave field to the electron spin defect layer and in which the cabling includes an optical fiber arranged to provide, from a first end of the optical fiber, a first light signal to the electron spin defect layer and to receive, at the first end of the optical fiber, a second light signal emitted by the electron spin defect layer.

Abstract: Disclosed herein is a biosensor capable of receiving bioelectric stimulation or bio-signals. The biosensor has a pillar-type electrode structure that is coated with a non-conductive material. The biosensor includes an electrode substrate, and an electrode structure having a plurality of pillar electrodes protruding on the substrate. The pillar-type electrode structure is coated with the non-conductive material in at least one of: a first coating structure in which at least one or more of the plurality of pillar electrodes are coated with the non-conductive material and at least a portion of a side surface of each of the coated pillar electrodes is coated with the non-conductive material; and a second coating structure in which at least one of a top surface of the substrate and bottom surfaces of the at least one or more of the pillar electrodes are coated with the non-conductive material.

Abstract: Disclosed is an electrocardiograph (ECG) lead wire. The left electrode (120) and the right electrode (130) of the ECG lead wire are stacked and enclose an accommodation hole (101) for an electrode contact to pass through. At least one of the left electrode (120) and the right electrode (130) is made of an elastic material and/or is driven by an elastic member, so that the left electrode (120) and the right electrode (130) can move relative to each other under the action of an external force to widen the accommodation hole (101), and can move relative to each other under an elastic action force to narrow the accommodation hole (101). Since the size of the accommodation hole (101) can change, the electrode holder can be adapted to electrode contacts of various sizes on the market and makes same be firmly connected, thereby ensuring the stability and reliability of signal transmission.

Abstract: A catheter is disclosed comprising: a connector including a plurality of first contacts and one or more second contacts; a shaft including a plurality of electrodes, each electrode being coupled to a different one of the plurality of first contacts; a memory coupled to at least one of the second contacts, wherein the memory is configured to: store a pinout map identifying an order in which the plurality of electrodes is coupled to the plurality of first contacts; and provide the pinout map to an external device via one or more of the second contacts after the connector is coupled to the external device.

Abstract: An electrode pad with a defibrillation circuit and a separate ECG tracing circuit. The electrode pad includes a foam base layer, first and second conductive layers, and a hydrogel layer. The foam base layer has a first side and the first conductive layer is centrally located on the base layer. The first conductive layer has a first circuit configured to provide a defibrillation current. The second conductive layer extends at least partially around the first conductive layer on the first side of the base layer. The second conductive layer has a separate second circuit configured to receive an electrical signal. The hydrogel layer covers the first and second conductive layers on the first side of the base layer. The electrode pad additionally includes an electrical connector attached to the first and second conductive layers. The electrical connector is configured for providing a voltage to the first and second conductive layers.

Abstract: A motor control score is automatically generated for a subject based on electroencephalography (EEG) data represented as a plurality of EEG waveforms obtained from a plurality of EEG electrodes. Each waveform is separated into at least one window, containing a portion of the EEG waveform representative of neural activity corresponding to a movement performed by the subject. At least one or more frequency components and/or signal components are determined from the EEG data in the window, and a motor control score is determined based on these components. The frequency components may correspond to event-related desynchronization (ERD) response frequency band and event-related synchronization (ERS) response frequency band. In other embodiments, the frequency components correspond to a phase response and the signal components correspond to a signal power spectrum density of the window, which are provided to a primary neural network model to determine the motor control score.

Abstract: A mobile apparatus adapted to be handheld and configured for electronic processing of blood sugar affecting factors includes a first central processing unit arranged for processing of patient critical information objects, at least one memory comprising a plurality of in advance stored food units and values of at least one related blood sugar affecting parameter, an input unit arranged to provide user input, such as a choice of food units and an amount thereof, a display arranged for visualization of food units for said user input, and for visualization of summed up blood sugar affecting parameters, and a second central processing unit arranged for processing of patient non-critical information objects.

Abstract: A non-transitory storage medium stores instructions readable and executable by at least one electronic processor (20) to perform an imaging method (100). The method includes: obtaining multi-parametric magnetic resonance (MR) imaging data parameterized by a diffusion weighting or perfusion weighting parameter and a magnetization relaxation parameter for a region of interest (ROI) of a patient; determining volume fraction maps of the ROI for each of a plurality of tissue types from the multi-parametric MR imaging data; and controlling a display device (24) to display a tissue composition map comprising or generated from the determined volume fraction maps.

Abstract: Skin torsionometers, methods and systems for using such skin torsionometers, and systems including a skin torsionometer, computing device configured to capture images, and an application (app) for determining the tautness of skin are described herein.

Abstract: Examples of methodologies and technologies for determining changes in one or more skin conditions of a user over time are described herein. Any changes in skin conditions over time may be used as a diagnosis and/or treatment aid for a physician. Any changes in skin conditions over time may be also used in a computer implemented method that provides diagnosis and/or treatment recommendations.

Abstract: A method of monitoring the status of a body of a person during sleep, said method comprising:—retaining in or adjacent the mouth or nose of said person an electronic detector which detects indications of the state of said body,—wirelessly transmitting a first data stream representing said indications to a data receiving means,—transmitting said first data stream from said data receiving means to a data processing means,—processing said first data stream within said data processing means to produce a second data stream representing said indications, or conclusion drawn from said indications, and—displaying a visual representation of said indications or conclusions.

Abstract: Systems and methods for measuring biologically and behaviorally based responses to social media, locations, or experiences and providing instant and continuous feedback in response thereto are disclosed. An example system includes a first sensor to determine an emotional response of a user exposed to a social media application, a second sensor to determine a current activity of the user, and a third sensor to determine an environment of the user. The example system also establishes a priority schedule based on the emotional response, the current activity, and the environment. The system also correlates, based on the priority schedule, an advertisement with at least one of the emotional response, activity, or the environment. In addition, the example system presents the advertisement based on the priority schedule and the correlation of the advertisement with the at least one of the activity, the environment, or the emotional response.

Abstract: A method for monitoring a patient during his sleep, comprising: monitoring the thoracic breath of the patient; monitoring the abdominal breath of the patient; detecting a sleep apnea syndrome (SAS) event (102); in reaction to the detection of N such SAS events, N being an integer equal or larger than 1, performing an additional measurement (105) to detect an abnormal condition.

Abstract: A pain level indicator assembly includes an increase control that is holdable by a patient and a decrease control that is holdable by the patient. A display unit is provided and the display unit is positionable in a prominent position in a healthcare environment to be visible to a caregiver. The display unit is in remote communication with each of the increase control and the decrease control. Additionally, the display unit displays gauge indicia comprising a pain meter ranging between a predetermined negative integer and a predetermined positive integer. The display unit is actuated to display a point along the gauge indicia to communicate the patient's pain level to the caregiver.

Abstract: Disclosed are a joint manipulation device and system for increasing the range of motion of a joint of a user, and monitoring the compliance of the user's operation of the joint manipulation device to standards or guidelines set by a monitoring entity. Certain sensors associated with the joint manipulation device may cause an indicator to transmit an alert to the user based on whether or not the device is sufficiently engaged with a limb or joint of the user to be considered in compliance. Additionally, progress data associated with the range of motion of the user's joint may be obtained by a sensor assembly and transmitted to one or more systems associated with the device system. Progress data obtained during a period of non-compliant use of the device may be excluded from the transmitted data, thereby generating a set of compliant progress data for accurate analysis of device effectiveness.

Abstract: An example system for monitoring and delivering therapy to a patient includes a monitor module with patient monitoring capability, and a manifold that is operable to provide an electrical connection between the monitor module and cables connecting to sensors for collecting physiologic monitoring data of a patient, and to provide a gas connection between the monitor module and tubing for delivering treatment to or collecting additional physiologic monitoring data from the patient. The manifold includes a connector for mechanically connecting the manifold to the monitor module, and the connector also for mechanically disconnecting the manifold from the monitor module while maintaining the cables and the tubing coupled to the patient. In some examples, the system can also include a cot including a second set of monitoring electronics with patient monitoring capability, the cot including a port for coupling with the connector of the manifold.

Abstract: Safe and effective exercise poses a specific set of challenges for subjects diagnosed with diabetes. These challenges include the coordination of exercise with blood glucose monitoring and insulin administration. Failure to coordinate these factors effectively can lead to various pathologies related to aberrant blood glucose levels. Presented herein are methods, systems, algorithms, computer program products, and computer-executable code for exercise guidance and instruction specific to diabetes relief and management. The approaches as disclosed herein can help ameliorate, slow, or reduce a likelihood of developing a diabetic condition.

Abstract: The invention relates to a system and a method for providing an exacerbation risk score for a respiratory disease of a patient. The system measures a heart signal and/or a blood circulation signal of a patient and detects cough events and sneeze events in the measurement data. The cough events and sneeze events are indicative for an onset of a contagion and/or an allergy, which can rapidly exacerbate a respiratory disease of the patient. Thus, the system is configured for providing unobtrusively an exacerbation risk score to the patient and/or to a physician.

Abstract: A patient health management platform accesses a metabolic profile for a patient and biosignals recorded for the patient during a current time period comprising sensor data and/or lab test data collected for the patient. The platform encodes the biosignals into a vector representation and inputs the vector representation into a patient-specific metabolic model to determine a metabolic state of the patient at a conclusion of the current time period. The patient-specific metabolic model comprises a set of parameter values determined based on labels assigned to the previous metabolic states and a function representing one or more effects of the plurality of biosignals of the personalized metabolic profile. The platform compares the determined metabolic state of the patient to a threshold metabolic state representing a target metabolism.

Abstract: A patient health management platform determines of a metabolic state for a first time period. The platform generates a patient-specific treatment recommendation for a second time period following the first time period that identifies objectives for the patient to complete to improve the metabolic state determined for the first time period. Periodically during the second time period, the platform receives recordings of patient data indicating foods consumed by the patient, medication taken by the patient, and/or symptoms experienced by the patient. The platform compares the received recordings of patient data from the second time period to the generated patient-specific treatment recommendation to determine a number of objectives completed by the patient and updates a score representing n adherence of the patient to the patient-specific treatment recommendation based the number of completed objectives.

Abstract: Numerous aspects of communication devices, methods, and systems are described in this application. One aspect is an apparatus comprising an energy generator comprising a plurality of generator elements operable to output a plurality of different energy types in a signal direction toward the skin. Each generator element of the plurality of generator elements may be independently operable, when the energy generator is positioned relative to skin, to communicate with different nerves associated with the skin by outputting a different portion of an energy signal in the signal direction toward the skin with one energy type of the plurality of different energy types.

Abstract: A detachable physiological monitoring device includes a detachable electrode and an electrical coupling unit electrically connected to the detachable electrode. The electrical coupling unit includes a flexible substrate, a fabric, and a conductive wire. The flexible substrate has a first surface and a second surface opposite to the first surface, and the flexible substrate has a first opening. The fabric is disposed at the first surface of the flexible substrate. The fabric includes a second opening corresponding to the first opening and a conductive region surrounding the second opening. The conductive wire has a first terminal and a second terminal opposite to the first terminal, and the first terminal is connected to the conductive region. The detachable electrode contacts the conductive region, and is connected to the conductive wire.

Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.

Abstract: An adhesive layer applicator for a body-mountable device is disclosed. The applicator includes a housing defining a first opening through which a chamber is accessible, and a plurality of adhesive layers and a plurality of adhesive liners alternately stacked on a floor that is movable within the chamber. The size and shape of the opening corresponds to the size and shape of the body-mountable device. The housing is configured to receive at least a portion of the body-mountable device through the opening. A second opening is formed in each adhesive layer in the plurality of adhesive layers and a gel is accommodated within the second openings.

Abstract: A wearable sensing device is disclosed. The wearable sensing device includes a plurality of electrodes. A corresponding group of microprobes associated to each of the plurality of electrodes is provided. Another group of microprobe associated with a trigger circuit is provided and configured to determine attachment of the wearable sensing device to the user.

Abstract: A catheter insertable into a cavity of a patient for monitoring pressure including a first lumen for drainage from the cavity and an expandable balloon. The balloon has a liquid containing chamber to monitor pressure within the cavity of the patient as pressure on the outer wall of the balloon deforms the balloon and compresses the liquid within the balloon. An exit port provides passage of air from an interior of the balloon to outside the catheter. A membrane has plurality of pores dimensioned to enable passage of air but prevent passage of the liquid therethrough. A pressure sensor communicates with the liquid containing chamber for measuring pressure based on compression of liquid caused by deformation of the expanded balloon.

Abstract: A sensing device can be used for ambulatory urodynamics. The sensing device can include an elongated outer housing constructed of flexible material that can curve within a patients bladder. At least a portion of the outer housing can be filled with a non-compressible fluid. A flexible printed circuit board can be disposed within the outer housing to curve with the outer housing. The printed circuit board can include a pressure sensor, comprising a diaphragm, to collect pressure data; a microcontroller miming control software; and a wireless transmitter to transmit the pressure data. A battery can be disposed within the outer housing and coupled to the printed circuit board. The flexible material of the outer housing is configured to be displaced by a pressure within the patients bladder, the displacement is transmitted through the non-compressible fluid to the pressure sensor that provides the pressure data based on the displacement.

Abstract: Methods, systems, and method for predicting sensor measurement quality.

Abstract: A biopotential measurement device includes: a branching section that branches a biopotential into plural analog potentials; a first conversion section that converts one of the analog potentials branched by the branching section into a digital potential on the basis of a designated first conversion condition; and a second conversion section that converts the other of the analog potentials branched by the branching section into a digital potential on the basis of a second conversion condition. The amount of data obtained after a conversion with the second conversion condition is smaller than the amount of data obtained after a conversion with the first conversion condition.

Abstract: Certain aspects of the present disclosure relate generally to a method for identifying a risk of sepsis in a body of a patient. The method includes measuring lactate concentrations associated with the body over one or more time periods. The method further includes identifying the risk of sepsis based on the lactate concentrations.

Abstract: Methods, systems, and apparatuses are described for associating dielectric properties with a patient model.

Abstract: A physiological signal sensing and compensation system is provided, for contacting an object to be measured and sensing a physiological signal. The physiological signal sensing and compensation system includes a physiological signal sensing module, a compensation module, and a computing unit. The physiological signal sensing module provides an initial sensing signal. The compensation module includes a collecting mechanism for collecting a physiological liquid of the object to be measured. The compensation module provides a compensation signal according to the physiological liquid collected by the collection mechanism. The computing unit is electrically connected to the physiological signal sensing module and the compensation module, and calculates and provides a compensated sensing signal based on the initial sensing signal and the compensation signal.

Abstract: A user, such as an elderly person, may be assisted by an assistance device in his or her caregiving environment that operates in conjunction with one or more server computers. The assistance device may execute a schedule of assistance actions where each assistance action is associated with a time and is executed at that time to assist the user. An assistance action may present an input request to a user, process a voice input of the user, and analyze the voice input to determine that the voice input corresponds to a negative response event, a positive response event, or a non-response event. Based on the categorization of one or more voice inputs as negative response events, positive response events, or non-response events, it may be determined to notify a caregiver of the user, for example where the user has not responded to a number of assistance actions.

Abstract: An imaging system and methods including a gantry defining a bore and an imaging axis extending through the bore, and at least one support member that supports the gantry such that the imaging axis has a generally vertical orientation, where the gantry is displaceable with respect to the at least one support member in a generally vertical direction. The imaging system may be configured to obtain a vertical imaging scan (e.g., a helical x-ray CT scan), of a patient in a weight-bearing position. The gantry may be rotatable between a first position, in which the gantry is supported such that the imaging axis has a generally vertical orientation, and a second position, such that the imaging axis has a generally horizontal orientation. The gantry may be displaceable in a horizontal direction and the system may perform a horizontal scan of a patient or object positioned within the bore.

Abstract: A positron emission tomography (PET) technique that can enhance the image resolution and system sensitivity of a clinical PET/CT scanner for imaging a whole body or a target region of a subject is provided. The system includes a detector array and a detector panel. The detector array includes an array of gamma ray detectors defining a field of view of a scanner and configured to detect at least one coincidence event. The detector panel includes an array of gamma ray detectors having a higher intrinsic spatial resolution than the detector array and positioned in closer proximity to a patient table than the detector array. The detector panel is positioned outside the field of view defined by the detector array during at least a portion of scanning by the PET system. The detector panel is configured to detect at least one coincidence event in cooperation with the detector array.

Abstract: An apparatus comprising a radiation source, coincident positron emission detectors configured to detect coincident positron annihilation emissions originating within a coordinate system, and a controller coupled to the radiation source and the coincident positron emission detectors, the controller configured to identify coincident positron annihilation emission paths intersecting one or more volumes in the coordinate system and align the radiation source along an identified coincident positron annihilation emission path.

Abstract: In an image processing device (300), a position determiner (313) determines, in a three-dimensional image showing an upper jaw part of a subject and a lower jaw part of the subject, positions of left and right mental foramina of the lower jaw part and a position of an incisors tube of the upper jaw part. A coordinate system setter (314) sets a three-dimensional coordinate system having an origin at a position established by the positions of the left and right mental foramina and the position of the incisors tube that are determined by the position determiner (313), the three-dimensional coordinate system including: a first coordinate axis that passes through the origin and the position of the incisors tube; a second coordinate axis that is perpendicular to the first coordinate axis and a straight line connecting the position of the left mental foramen and the position of the right mental foramen; and a third coordinate axis that is perpendicular to the first coordinate axis and the second coordinate axis.

Abstract: Disclosed are a method of and an apparatus for 3D visualization of the root canal curvature of a tooth. The method includes (a) displaying a CT image of one or more teeth on the basis of CT image data, (b) three-dimensionally rendering at least a portion of the root canal of a target tooth when a dental practitioner selects the target tooth from the CT image, and (c) visualizing a curvature in a region of the root canal that is three-dimensionally rendered using a visual factor.

Abstract: The present invention is directed to a method of multi-motion compensation for high-quality cone-beam CT of the head. A multi-stage approach is incorporated that includes a pre-conditioning stage in which an initial estimation of the motion trajectory is obtained with 3D-2D registration using the motion-contaminated CBCT and projection data. In the present invention, the motion-contaminated CBCT is used as a basis for 3D-2D registration in the pre-conditioning stage to capture large amplitude, rapid movements of the head and provide better initialization of the autofocus solution.

Abstract: A multi-axis imaging system comprising an imaging gantry with an imaging axis extending through a bore of the imaging gantry, a support column that supports the imaging gantry on one side of the gantry in a cantilevered manner, and a base that supports the imaging gantry and the support column. The imaging system including a first drive mechanism that translates the gantry in a vertical direction relative to the support column and the base, a second drive mechanism that rotates the gantry with respect to the support column between a first orientation where the imaging axis of the imaging gantry extends in a vertical direction parallel to the support column and a second orientation where the imaging axis of the gantry extends in a horizontal direction parallel with the base, and a third drive mechanism that translates the support column and the gantry in a horizontal direction along the base.

Abstract: A system and method for providing dynamic 3-D anatomical visualizations generates a 3D visualization of a patient's airway that may be dynamically transformed to characterize changes to the airway (e.g., as the patient breathes, when patient performs a Mueller's manoeuvre, and/or in response to mandibular repositioning). The 3D visualization is generated based on an integration of static 3D image data and acoustic reflection measurements of the airway determined and provided by an acoustic reflection measurement device. The movements or changes to the region of interest may be determined based on real-time dynamic readings taken by the acoustic reflection measurement device, and the 3D visualization may be transformed in real-time or near real-time stream based on the dynamic readings. The transformation of the 3D visualization provides an animated visualization of the airway.

Abstract: The present disclosure is related to systems and methods for controlling an imaging device. The system may include an imaging device, a voice processing device, and a terminal. The imaging device may be configured to image a subject. The voice processing device may be configured to receive a first voice signal from or transmit a second voice signal to the subject when the subject is positioned within the imaging device. The terminal may be configured to receive a third voice signal from or transmit a fourth voice signal to a user.

Abstract: Methods and systems are provided for medical imaging systems. In one embodiment, a method for a medical imaging system comprises acquiring emission data during a positron emission tomography (PET) scan of a patient, reconstructing a series of live PET images while acquiring the emission data, and tracking motion of the patient during the acquiring based on the series of live PET images. In this way, patient motion during the scan may be identified and compensated for via scan acquisition and/or data processing adjustments, thereby producing a diagnostic PET image with reduced motion artifacts and increased diagnostic quality.

Abstract: An object of the present invention is to provide an analysis method capable of analyzing time-series images by a method simpler than ever.