Patents Issued in July 20, 2021
  • Patent number: 11065379
    Abstract: Methods and for treatment of cancer and other diseases including complications from late stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed.
    Type: Grant
    Filed: April 11, 2020
    Date of Patent: July 20, 2021
    Assignee: VERYHERMIA ACQUISTION, INC.
    Inventors: Roger Vertrees, Jan Winetz
  • Patent number: 11065380
    Abstract: A patient care system is configured for infusing fluid to a patient. The system includes a plurality of modular fluid infusion pumps that each has a connector for connecting to a modular programming unit or to one another. Systems and methods are configured for verifying that the connectors are reliably performing their functions or communicatively connecting the pumps to one another or to the programming unit.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: July 20, 2021
    Assignee: Carefusion 303, Inc.
    Inventor: Andre Gamelin
  • Patent number: 11065381
    Abstract: A patch pump including a medicament reservoir having an inner surface defining an elongate piston engagement pathway, an electric motor having a rotary drive output element, a piston replaceably axially fixed to the electric motor. The piston having an outer surface arranged for sealing engagement with the inner surface of the medicament reservoir, the piston also including a rotary to longitudinal drive converter receiving a rotary drive input from the rotary drive output element of the electric motor and providing a longitudinal drive to the reservoir, thereby driving the medicament reservoir in longitudinal motion relative to the piston in which the elongate piston engagement pathway defined by the inner surface of the medicament reservoir is displaced axially and in sealing engagement with the outer surface of said piston.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: July 20, 2021
    Assignee: E3D A.C.A.L.
    Inventors: Ziv Naftalovitz, Ilan Shopen, Tsachi Shaked
  • Patent number: 11065382
    Abstract: The present disclosure relates to an apparatus for providing access to bone marrow and delivering a quantity of fluid to an intraosseous space. The apparatus may include a driver having a housing and a drive shaft, and a plunger operating and cartridge drive mechanism for releasably retaining a portion of a cartridge assembly having a plunger assembly. A plunger operating assembly may be disposed within a longitudinal bore of the plunger operating and cartridge drive mechanism. The plunger operating assembly may include a plunger barrel having a chamber configured to receive a portion of the plunger assembly of the cartridge assembly. The apparatus may also include a drive housing for transmitting rotational forces from the drive shaft to the cartridge assembly.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: July 20, 2021
    Assignee: TELEFLEX LIFE SCIENCES LIMITED
    Inventors: Larry J. Miller, David S. Bolleter, Charles M. Schwimmer, Robert A. Wilk
  • Patent number: 11065383
    Abstract: A connector provided with a housing which defines an insertion section into which a male connector is inserted from the outside and a flow path communicating with the insertion section and an elastic valve body which has a slit and blocks the insertion section. The housing includes a tip receiving section formed on an inner wall defining the flow path, the tip receiving section receiving a tip of the male connector inserted through the slit of the elastic valve body. The tip receiving section is formed on only a part of the inner wall in a cross section that is perpendicular to an insertion direction of the male connector and includes at least a part of the tip receiving section.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 20, 2021
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Yasuhiro Ueda
  • Patent number: 11065384
    Abstract: An administration set for an infusion pump includes a free-flow prevention device having a movable plunger that includes a cam surface defining an uneven profile along a direction of movement of the plunger, wherein the shape of the cam surface profile indicates the administration set is authorized for use with the infusion pump and may further indicate the specific type of administration set. A sensor in the infusion pump senses movement of the plunger as a platen of the infusion pump is latched and generates a profile signal in the time domain representative of the cam surface profile. A processor evaluates the profile signal and controls operation of the pump to protect a patient from improper loading of an administration set, use of an unauthorized administration set, and/or use of an invalid type of administration set for a chosen infusion protocol.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: July 20, 2021
    Assignee: Curlin Medical Inc.
    Inventors: Azur Azapagic, Mohan Jonathan Barkley
  • Patent number: 11065385
    Abstract: The present disclosure provides systems that include a flow probe that senses fluid flow or mass flow of fluid delivery to a patient. Based at least in part on the sensed fluid or mass flow, the flow probe provides flow-related data (e.g., volume or mass flow rate) that the system uses to derive a volume of fluid being delivered. The fluid can be delivered from an IV bag, another in-line port, or a combination of the two. The disclosed systems provide fluid volume and/or fluid rate for display to a clinician and an informative understanding of what volume of fluid/mass a patient has received.
    Type: Grant
    Filed: June 8, 2018
    Date of Patent: July 20, 2021
    Assignee: Edwards Lifesciences Corporation
    Inventors: Brian R. Hipszer, Morgan T. McKeown, Feras Al Hatib, Peter James Ifft, Geertruida Lucretia Van Der Sar, Peiyuan Li
  • Patent number: 11065386
    Abstract: An automatic medication injection device that provides a user with audible notice of injecting progress. The device in one form includes a plurality of sound elements located on drive mechanism portion that inserts within a barrel of a container of medication to advance a sealing plunger of that container. The device also includes at least one actuating element movable axially with the container of medication within the device housing, which at least one actuating is element arranged to engage the plurality of sound elements to generate audible notices as the advancing portion moves past the at least one actuating element when advancing the sealing plunger for an injection.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 20, 2021
    Assignee: Eli Lilly and Company
    Inventors: William G. Atterbury, Steven Michael Madland, Christopher Paul McKenzie, Jessica Diane Modlich
  • Patent number: 11065387
    Abstract: An activation mechanism for a medicament delivery device is provided having a housing elongated along a generally longitudinal axis, a spring-biased drive member, a locking unit, movable from a locked position, preventing longitudinal movement of said drive member, to an unlocked position, a first activation member movable relative to the housing; a second activation member movable relative to the housing, and wherein the locking unit comprises a key member, movable relative to the locking unit, wherein the first activation member and the second activation member are configured to move the locking unit from the locked position to the unlocked position, wherein upon actuation, the first activation member and the second activation member cooperate in interacting with the key member to move the key member to the cooperating position and to move the locking unit from the locked position to the unlocked position.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: July 20, 2021
    Assignee: SHL MEDICAL AG
    Inventor: John Laiosa
  • Patent number: 11065388
    Abstract: A cartridge (100) for packaging a medicament and being suitable for use with multiple different types of dosing device is described, together with dosing devices and adaptors for dosing devices. The cartridge includes a generally tubular body (102) having an interior cavity (104), a closure member (106) disposed at a distal end of the body and comprising a sealing element (128), a piston member (108) disposed in the cavity to contain the medicament between the piston member and the sealing element (128), a coupling element (114) disposed at the distal end of the body for coupling the cartridge to a dosing device (200) or to an adaptor for a dosing device, and a seal arrangement (126, 129) for receiving a sealing element release member (214) of the dosing device or adaptor.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: July 20, 2021
    Assignee: Owen Mumford Limited
    Inventors: Toby Cowe, Timothy Evans, Colin Webb, Jake Mallon
  • Patent number: 11065389
    Abstract: An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: July 20, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl, Christiane Schneider
  • Patent number: 11065390
    Abstract: A drive mechanism for a delivery device comprising a rotator comprising an outer surface and an inner surface, the rotator configured to rotate from a first position to a second position; and a needle cover comprising an inner surface that engages the outer surface of the rotator. An end of injection indication device is positioned at least partially within a plunger rod spring, the end of injection indication device providing a signal to a user of the drive mechanism that an injection has been completed.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: July 20, 2021
    Assignee: SHL MEDICAL AG
    Inventors: Jason Frost, Mattias Daniel, Sebastian Karlsson
  • Patent number: 11065391
    Abstract: A medication injection device comprising a medication container to contain medication; a connector provided with a blocking feature; a push rod having a plurality of teeth disposed along the length, and a spring biasing against the push rod to move proximally. The spring can be compression spring, extension spring, torsion spring, or constant force spring. By enabling or disabling engagement between the blocking feature on the connector and the tooth on the push rod, the push rod is either prevented from moving distally or allowed to move distally. The medication is drawn into the medication container when the push rod moves proximally and the medication is dispensed out of the medication container when the push rod moves distally.
    Type: Grant
    Filed: February 9, 2020
    Date of Patent: July 20, 2021
    Inventor: Min Wei
  • Patent number: 11065392
    Abstract: The disclosure relates to injectors that are configured to inject and deliver medicaments and other fluids from a syringe into a target site.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: July 20, 2021
    Assignee: Action Medical Technologies, LLC
    Inventors: Joseph B. Hoffer, Mark W. Pursel, Kevin C. O'Connor, Andrew D. Contreras, James P. McCans
  • Patent number: 11065393
    Abstract: A device for administering a fluid product, the device including a first housing part provided with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: July 20, 2021
    Assignee: Ypsomed AG
    Inventors: Philippe Kohlbrenner, Daniel Kuenzli, Christoph Meier, Peter Stettler, Juergen Wittmann, Martin Wittwer
  • Patent number: 11065394
    Abstract: The invention relates to a syringe with a retractable needle comprising a barrel (2) having a nozzle (19) integrated in a male Luer adapter element (26); a piston (3) slidably arranged in the barrel (2) and coupled to a sealing element (16), said sealing element (16) having a central channel (20); a needle assembly comprising a needle (4), a needle holder (6) and a female Luer adapter element (7); a spring assembly arranged in the piston (3) comprising a spring sleeve (12), a spring (13) mounted on the spring sleeve (12), a spring tensioning element (14) located on the spring sleeve (12) and held in position by the piston wall, and a plunger (15) mounted within the spring sleeve; and a piston cap (10); said piston (3) being coupled to the sealing element (16) by means of the spring tensioning element (14); said spring sleeve (12) being held in position within the piston (3) by a ring element (18) protruding from the inner wall of the piston (3) and supporting the proximal end of the spring sleeve (12), the sp
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: July 20, 2021
    Assignee: GUANGDONG INTMED MEDICAL APPLIANCE CO., LTD.
    Inventor: Kewang Tu
  • Patent number: 11065395
    Abstract: A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a device shield interconnected to a lock collar with flexible member and biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. As the device shield moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar and disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: July 20, 2021
    Assignee: Safety Syringes, Inc.
    Inventor: Ryan Schoonmaker
  • Patent number: 11065396
    Abstract: A needle cannula (100) and a method for producing a needle cannula comprising providing a needle cannula tube (10) with an end portion (30). The end portion (30) comprises an outer surface, and a given type of steel comprising carbon (C) in 0.07 to 0.15% by mass, silicon (Si) in 0.50 to 1.00% by mass, manganese (Mn) in 5.0 to 7.5% by mass, phosphorus (P) in 0 to 0.030% by mass, sulfur (S) in less than or equal to 0.015% by mass, chromium (Cr) in 17.5 to 19.5% by mass, nickel (Ni) in 6.5 to 8.5% by mass, and nitrogen (N) in 0.20 to 0.30% by mass. The method further comprises establishing an electrochemical reaction to remove material from the outer surface of the end portion (30), and thereby providing a needle cannula (100) with a tapered end portion.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: July 20, 2021
    Assignee: Novo Nordisk A/S
    Inventors: Jacqueline Trosborg, Jens Christian Uggerhoej
  • Patent number: 11065397
    Abstract: An inhalation device including a housing, which encloses a liquid reservoir in which the liquid is stored before discharge, and an applicator head with a nebulization chamber and an applicator piece connected thereto, wherein the applicator piece is designed either as a mouthpiece, to be received in the mouth of a patient, or as an inhalation mask, to sealingly cover the mouth, the nose, or the mouth and the nose. The inhalation device furthermore has a discharge channel which connects the liquid reservoir to the applicator head. The inhalation device includes at the end of the discharge channel a nozzle plate with a large number of nozzle openings which serve to generate an inhalation mist and through which the liquid from the liquid reservoir is conveyed into the nebulization chamber.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: July 20, 2021
    Assignee: Aptar Radolfzell GMBH
    Inventor: Günter Nadler
  • Patent number: 11065398
    Abstract: An aerosol generating apparatus is disclosed. The apparatus includes a liquid container, an adaptor and a driving element. The liquid container includes a perforated membrane through which a liquid can permeate. The liquid container further includes a first mating element. The adaptor includes a second mating element. The driving element includes a piezoelectric element coupled to a substrate. The driving element is accommodated by the adaptor and the substrate includes an aperture and a projection. The first and second mating elements are adapted to detachably and slidably mate with each other such that the aperture of the substrate aligns proximately to the center of the perforated membrane. The first and second mating elements are further adapted for relative movement along a sliding axis. The projection is adapted to press against the perforated membrane.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: July 20, 2021
    Assignee: MICROBASE TECHNOLOGY CORP.
    Inventors: Shu-Pin Hsieh, Yi-Tong Chen, Po-Chuan Chen, Ting-Kai Tsai, Chih-Wei Lu, Laurence Kao
  • Patent number: 11065399
    Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: July 20, 2021
    Assignee: STAMFORD DEVICES LIMITED
    Inventors: Joseph Grehan, Niall Smith
  • Patent number: 11065400
    Abstract: Inhalation delivery of aerosols containing small particles is described. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present disclosure, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: July 20, 2021
    Assignee: ALEXZA PHARMACEUTICALS, INC.
    Inventors: Craig C. Hodges, Peter M. Lloyd, Daniel Mufson, Daniel D. Rogers, Martin J. Wensley
  • Patent number: 11065401
    Abstract: A stand for an elongated medicament delivery device having a distal end and a proximal end the stand comprising a base section for supporting the stand on a support surface; a holding section for receiving the distal end of the medicament delivery device; and a body section arranged between the base section and the holding section; wherein the holding section is configured to hold the medicament delivery device in a substantially vertical orientation when the base section is positioned on the support surface. The holding section comprises an elastically deformable material for providing an elastic squeeze fit around the distal end of the medicament delivery device when received in the holding section. A system comprising an elongated medicament delivery device and a stand for supporting the medicament delivery device is also provided.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: July 20, 2021
    Assignee: SHL MEDICAL AG
    Inventor: Lucas Carpenter
  • Patent number: 11065402
    Abstract: A vaporization device includes a housing, a fluid pathway extending through the housing, a heating chamber with a heating element proximate a first housing end, a control circuit and a battery disposed within the housing. The heating chamber is in fluid communication with the fluid pathway. The first chamber end is open and the second chamber end includes a closed end with one or more vents. The heating element is operable to generate heat at a predetermined vaporization temperature. The control circuit has a switch operable to control a flow of current from the battery to the heating element. In use, the predetermined vaporization temperature is sufficient to vaporize phyto material in contact with the heat at the predetermined vaporization temperature to emit a vapor. Inhaling from the second housing end draws mixed vapor and air through the fluid pathway.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: July 20, 2021
    Assignee: GSEH Holistic, Inc.
    Inventor: Michael Alexander Trzecieski
  • Patent number: 11065403
    Abstract: A blister strip advance mechanism includes: an indexing gear train; drive mechanism configured to drive the indexing gear train; and a hub including a recess shaped to engage a first blister of a blister strip, the hub being rotatable by the indexing gear train to engage the first blister in the recess and move the engaged blister strip such that a second blister is moved to a dosing position at which the second blister can be emptied; wherein the indexing gear train is configured to temporarily disengage the drive mechanism from the hub when the second blister is in the dosing position. Also disclosed is a dosing mechanism including the blister strip advance mechanism; an inhaler including the dosing mechanism; a method for advancing a blister strip; and a method for dosing a medicament including the method for advancing a blister strip.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: July 20, 2021
    Assignee: MICRODOSE THERAPEUTX, INC.
    Inventors: Travis Ernest Yoch, Robert R. Roberts, III
  • Patent number: 11065404
    Abstract: An electronic cigarette includes a shell and a mouthpiece. The external wall of the shell has an air inlet. An atomizer and a liquid-supply are in contact with each other. The air inlet, atomizer, and an aerosol passage are interconnected.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: July 20, 2021
    Assignee: FONTEM HOLDINGS 1 B.V.
    Inventor: Lik Hon
  • Patent number: 11065405
    Abstract: An electronic cigarette includes a ceramic heating element having a current conducting heating member on and/or in a body of ceramic material which is impenetrable to the liquid; a liquid delivery member to deliver liquid from a liquid storage to the heating element; a battery; and an electric circuit for electrically connecting the heating element to the battery. The body of ceramic material is to contact or be in close proximity to the liquid delivery member, to vaporize the liquid when the ceramic heating element produces heat. The electronic cigarette further includes a cartomizer part, having the liquid storage and the liquid delivery member, and a battery holding part, having the battery, the ceramic heating element, and the electric circuit. In an assembled state, the cartomizer part and the battery holding part are assembled. In a disassembled state, the cartomizer part and the battery holding part are separated.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: July 20, 2021
    Inventor: Dick Paul Voerman
  • Patent number: 11065406
    Abstract: An interface for positive pressure therapy includes a mask assembly, a headgear assembly and a connection port assembly. The mask assembly comprises a seal member that has an upper portion movably connected to an integrated lower portion, wherein the upper portion rolls during hinging movement of the upper portion relative to the lower portion. The headgear assembly allows connection to the mask assembly in a direction substantially normal to a direction of strap tension. The connection port assembly includes a swivel elbow with a valve member that controls flow through a port that opens toward the user.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: July 20, 2021
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Gregory James Olsen, Peter David Alexander Bearne, Leon Edward Evans, Matthew Roger Stephenson, Craig Robert Prentice, Bernard Tsz Lun Ip, Tony William Spear, Mark Arvind McLaren, Roheet Patel, Brad Michael Howarth, Jonathan David Harwood
  • Patent number: 11065407
    Abstract: Resuscitation apparatuses and methods for assisted ventilation are described herein. The apparatuses may include functional elements that allow the manual delivery of a prescribed volume to an adult or an infant lung. Furthermore, the apparatuses may inform and assure an emergency worker that an appropriate volume is being delivered and therefore lessen the possibility of barotrauma from over-delivery, or ventilatory distress from under-delivery. In some embodiments, the apparatuses include biomechanical and ergonomic functional elements that allow an adult hand to hold it in place during operation, while at the same time, allowing the user to actuate the apparatus to deliver only the necessary amount of volume suitable for an infant lung. In other embodiments, a volume-controlled design is applied to pediatric and adult resuscitation.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: July 20, 2021
    Assignee: SOLENO THERAPEUTICS, INC.
    Inventors: Constantine Andrew Gillespie, Otho Newman Boone, Pedro E. De La Serna, Anthony D. Wondka
  • Patent number: 11065408
    Abstract: A method for controlling the delivery of a breathing gas to a patient. The method comprises: delivering a flow of breathing gas to a patient, the breathing gas having a breathing gas flowrate and a fraction of inspired oxygen; measuring an oxygen saturation level of the patient; determining a respiratory rate of the patient; automatically adjusting the fraction of inspired oxygen of the breathing gas based on the measured oxygen saturation level of the patient and a breathing gas flowrate set-point; and automatically adjusting the breathing gas flowrate set-point based on the determined respiratory rate of the patient.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: July 20, 2021
    Assignees: UNIVERSITÉ LAVAL, UNIVERSITÉ DE BRETAGNE OCCIDENTALE, OXY'NOV INC
    Inventors: Francois Lellouche, Erwan L'Her, Benoit Gosselin, Quang-Thang Nguyen
  • Patent number: 11065409
    Abstract: This disclosure describes systems, methods, and apparatus for intubation where indicators of a bougie's axial orientation and insertion depth into the trachea are not visible. In particular, a bougie having one or more tactile indicators of axial orientation and/or depth of insertion are disclosed. The tactile indicators can include finger grooves and/or a ridge to name two examples.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: July 20, 2021
    Inventor: Shannon Sovndal
  • Patent number: 11065410
    Abstract: A molded breathing appliance for supporting a nasal oxygen tube having an upper bite rim, a lower bite rim, a moldable material disposed within the upper bite rim and lower bite rim for conforming to a patient's maxillary bite impression and mandibular bite impression, respectively, an L-shaped member extending outwardly perpendicular to the upper bite rim, and a transverse support disposed on the L-shaped member and configured with a plurality of sets of oxygen tube finger clamps to retain a nasal oxygen tube in proximity with a patient's nostrils.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: July 20, 2021
    Inventor: Leonard Feld
  • Patent number: 11065411
    Abstract: A customized sealing member is for a customized mask of a pressure support system. The steps to manufacture the customized sealing member include generating surface geometry data of a face of a patient, the surface geometry data corresponding to and representing a surface geometry of the face of the patient; generating customization data using the surface geometry data, the customization data representing how a seal blank should be modified for the patient; and customizing the seal blank using the customization data such that the customized seal blank is shaped according to the customization data.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: July 20, 2021
    Assignee: Koninklijke Philips N.V.
    Inventor: Lauren Patricia Chodkowski
  • Patent number: 11065412
    Abstract: An interface for positive pressure therapy includes a mask assembly and a headgear assembly. The mask assembly comprises a mask seal that is adapted to underlie the nose. The mask seal extends up the lateral sides of the nose. The mask seal has a primary seal below the nose and a secondary seal alongside the nose.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: July 20, 2021
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Matthew Roger Stephenson, Melissa Catherine Bornholdt
  • Patent number: 11065413
    Abstract: A patient interface to provide breathable gas to a patient, comprising: a plenum chamber assembly, comprising: a nasal plenum chamber at least partly defining an upper gas chamber; an oral plenum chamber at least partly defining a lower gas chamber; and a decoupling structure at least partly connecting the nasal plenum chamber and the oral plenum chamber and at least party defining a flow path; a top plate including at least one connection feature configured to releasably retain a first portion of a positioning and stabilising structure; and a faceplate configured to releasably retain a second portion of a positioning and stabilising structure.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: July 20, 2021
    Assignee: ResMed Pty Ltd
    Inventors: Adam Francis Barlow, Rupert Christian Scheiner, Lachlan Richard Goldspink, Lemmy Nga
  • Patent number: 11065414
    Abstract: A medical tube has a tube wall defining a passageway for transportation of gases and further has a first end and a second end. At least one end of the medical tube comprises one or more of a pre-formed pneumatic port component, a pre-formed electrical port component, and a pre-formed sensor port component. A cuff is over-moulded about and thereby connects the pneumatic port component, the electrical port component, and/or the sensor port component and at least a portion of the tube end.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: July 20, 2021
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Peter Nigel Coleman, Nathan Lee Gray
  • Patent number: 11065415
    Abstract: The present invention relates to a device and method of delivering inhaled Nitric Oxide (iNO) to a patient situated in a Magnetic Resonance Imaging (MRI) suite.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: July 20, 2021
    Assignee: Mallinckrodt Pharmaceuticals Ireland Limited
    Inventors: Craig Flanagan, David Newman, Jaron M. Acker, Craig R. Tolmie, Jim Potenziano
  • Patent number: 11065416
    Abstract: A therapeutic device that can diffuse essential oils, infuse frequency into liquids, emit frequency-driven lights, and produce solfeggio tones. The therapeutic device includes an enclosure, at least one oil-diffusing device, at least one frequency-infusing device, at least one frequency-tone generator, a first plurality of ambience lights, at least one vent, and a first controller. The enclosure is used to conceal and protect the electronic components. The at least one oil-diffusing device is used to diffuse fluids. The at least one frequency-infusing device is used to infuse frequency by vibration into fluids. The at least one frequency-tone generator is used to generate tones of different frequencies. The first plurality of ambience lights is used for aesthetic and therapeutic aspects. The at least one vent is used as an escape for the mist produced by the diffusion of the fluids. The first controller is used to manage the electronic components.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: July 20, 2021
    Inventor: Bena Ptah Tehuti Ra Speret
  • Patent number: 11065417
    Abstract: A catheter manufacturing method includes positioning a shaft in a cavity of a mold. The shaft is an elongated tubular body configured to be inserted into a living body. The mold includes a first mold die and a second mold die that contact one another to define a closed space which is the cavity. The method includes injecting a molding material into the cavity from a gate at a position between the proximal end and the distal end of the shaft in the axial direction. The injecting position is offset from the center of the shaft in the transverse direction. The method includes molding a hub onto the shaft by solidifying the injected molding material in the cavity onto the outer surface of the shaft.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: July 20, 2021
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Takito Inukai, Shun Matsushita, Yuya Otake, Kota Hamuro
  • Patent number: 11065418
    Abstract: A method of assessing bladder storage anomalies via utilization of an indwelling urinary drainage catheter is provided. A urodynamic assessment assembly is provided, the assembly characterized by a pressure sensor for vesical pressure measurement, a processor/controller for receiving, processing and/or displaying select urodynamic patient parameters comprising sensed/monitored pressure data, and a catheter balloon adaptor for operably uniting the pressure sensor of the urodynamic assessment assembly to a balloon inflation valve of the indwelling urinary drainage catheter, the indwelling urinary drainage catheter operably linked with the urodynamic assessment assembly.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: July 20, 2021
    Assignee: SRS Medical Systems, LLC
    Inventor: Lee Brody
  • Patent number: 11065419
    Abstract: A system can include a handle and a needle fixedly secured to the handle. The needle can include a distal tip that can be inserted through a sidewall of a vessel of a patient. The system can further include a catheter that defines a lumen through which the needle extends and includes an engagement surface at an interior thereof. A stiffener can be positioned within the lumen of the catheter at an exterior of the needle and can include an engagement surface that can press distally on the engagement surface of the catheter to advance the catheter distally over the needle and through a lumen of the vessel when the stiffener is advanced distally over the needle. The system can further include a stiffener hub attached to the stiffener, the stiffener hub being movably coupled with the handle so as to translate relative thereto.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: July 20, 2021
    Assignee: Piper Access, LLC
    Inventors: Jay Muse, Kevin Jerry Cook
  • Patent number: 11065421
    Abstract: A catheter curvature brace, catheter assembly and method for managing fluid in a patient, the brace being attachable to a distal portion of a shaft of a catheter and having an elongated frame with a distal end and a proximal end. The frame is formed with at least one curve in a relaxed curved configuration. At least two coupling elements are connected to the frame, each coupling element configured to engage an outer surface of the catheter. At least the frame is formed of an elastic, biocompatible material capable of being straightened by a force and then returning to the relaxed curved configuration after the force is removed, thereby bending the catheter to substantially conform to the relaxed curved configuration.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 20, 2021
    Assignee: INTEGRA LIFESCIENCES SWITZERLAND SARL
    Inventor: Alan Dextradeur
  • Patent number: 11065422
    Abstract: Devices, systems, and methods useful to engage tissue using suction and to perform medical procedures during sectional engagement. The present disclosure includes disclosure of a tension apparatus, comprising an elongated portion; and a head portion at a distal end of the elongated portion, the head portion comprising one or more arms, whereby a suction lumen extending along the elongated portion and the one or more arms terminates at one or more suction openings at each of the one or more arms.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: July 20, 2021
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Matthew Phillips, H. Toby Markowitz
  • Patent number: 11065423
    Abstract: A balloon catheter includes an inner shaft with a distal variant portion and a proximal variant portion. A bulged portion is provided at the distal end of a reinforcement member, and the bulged portion is configured to move in an axial direction between the distal variant portion and the proximal variant portion. Thus, the balloon catheter may smoothly pass through a curved blood vessel with improved kink resistance of the reinforcement member.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: July 20, 2021
    Assignee: ASAHI INTECC CO., LTD.
    Inventors: Kazuteru Segi, Takeharu Katsurada, Yuta Kubo
  • Patent number: 11065425
    Abstract: The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: July 20, 2021
    Assignee: Neurofluidics, Inc.
    Inventors: Shivanand Lad, William C. Mobley, Karoly Nikolich, Thomas Saul
  • Patent number: 11065426
    Abstract: Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: July 20, 2021
    Assignee: TARIS Biomedical LLC
    Inventors: Michael J. Cima, Heejin Lee
  • Patent number: 11065427
    Abstract: Provided is a method for manufacturing a transdermal absorption sheet which suppresses the cost of manufacturing equipment and prevents deterioration of a pharmaceutical preparation or a raw material thereof, and an intermediate. A mold filled with a first polymer solution is stored in a drying container in an aseptic environment, and the first polymer solution in the mold stored in the drying container is dried outside an aseptic environment. In a case where a surface of the drying container in which the mold is stored is irradiated with an electron beam from an electron beam source, a shield that shields an electron beam is arranged at a position on a straight line connecting the electron beam source and the needle-like recessed portions.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: July 20, 2021
    Assignee: FUJIFILM Corporation
    Inventors: Kenichiro Tamaki, Satoshi Wakamatsu
  • Patent number: 11065428
    Abstract: Microneedle arrays for introducing an active ingredient through a skin surface of a subject can include a base layer, a plurality of microneedles projecting from the base layer, and an active ingredient. Each of the microneedles comprises an elongate body having a proximal portion and a distal portion, in which the proximal portion is attached to the base layer. Each of the microneedles comprises at least one dissolvable polymer. The active ingredient is incorporated in the elongate body, and the active ingredient is present only in the distal portion and at least internally in the distal portion.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: July 20, 2021
    Assignee: Allergan, Inc.
    Inventors: Futian Liu, Xiaojie Yu, Lance E. Steward, Guang Wei Lu, Patrick M. Hughes, Sheshadri Neervannan
  • Patent number: 11065429
    Abstract: Provided is a method of producing a microneedle array unit which is capable of suppressing damage to a microneedle array.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: July 20, 2021
    Assignee: FUJIFILM Corporation
    Inventors: Yuka Kobayashi, Yasuhiro Sekizawa
  • Patent number: 11065430
    Abstract: The subject invention is directed to a new and useful coupling system for connecting a tube set to a trocar. More particularly, the system includes a trocar connector having no more than two coaxial flow passages formed therein including an inner flow passage and an outer flow passage. The inner flow passage is defined by an inner annular wall and the outer flow passage is defined between the inner annular wall and an outer annular wall. A dual lumen tube set is included with a first tube having a first diameter and a second tube having a second diameter that is greater than the diameter of the first tube. The system further includes a coupling including a generally cylindrical body having a first end portion configured to mate with the two coaxial flow passages of the trocar connector and a second end portion configured for attachment to the two tubes of the dual lumen tube set.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: July 20, 2021
    Assignee: Surgiquest, Inc.
    Inventors: Earl M. Zergiebel, Michael J. Augelli, Kenneth Blier