Abstract: The present invention provides an endoscopic device for examination cum sample collection of an orifice of a user's body. In particular, the device is useful for vaginal and cervical examination. The device comprises a camera attached on the probe along with a radial luminous system and cytobrush for sample collection attached within the probe. A latex balloon and air flow directly through port are provided to inflate the vaginal cavity. The invention also provides the method for sample collection and supervision through controlled camera.

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Abstract: Devices and methods for extraction and processing of substantiagelatineafuniculi umbilicalis (Wharton's Jelly) from an umbilical cord.

Abstract: The present application discloses a device and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part and injecting a procoagulant material into the tissue tract adjacent a vascular access site via the sheath.

Abstract: Systems and methods for sealing tissue sites may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site and causing sealing of at least a portion of the target site.

Abstract: Medical devices for delivering compositions or medical articles to a patient are disclosed. The medical plug delivery devices can include a fluid delivery device (e.g., a syringe), a frame, and a rotatable magazine. The rotatable magazine can include a plurality of chambers that each hold a composition or a medical article (e.g., a medical plug). By rotating the rotatable magazine relative to the frame, material within the chambers of the rotatable magazine can be sequentially deployed to a patient.

Abstract: Retractor blades for a retractor system are disclosed. The blades are designed for use in preparing an area of the body for a surgical procedure. The retractor blades are configured with different lengths and with different blade tip geometries to facilitate engagement with vertebrae for the oblique lateral interbody fusion surgical approach.

Abstract: Devices and methods are disclosed herein for accessing the hip joint. A first device can be securely attached to the capsule of a joint. The first device can tent the capsule to increase the volume of the peripheral compartment. A second device can be biased against the first device to pierce the tented capsule and create a portal. Devices and methods are also disclosed herein for distending the capsule of a joint. A distention device may access a portal established within the capsule. The distention device can expand the capsule by applying an expansive force within the peripheral compartment. The distention device can maintain distention of the peripheral compartment while other devices access the joint.

Abstract: A soft tissue fixing anchor includes: an anchor member which is inserted to the bone cavity interior and prevented from moving in the bone cavity interior by the artificial joint when the artificial joint is implanted; and a suture of which one end portion is fixed to the anchor member and the other end portion is exposed to a bone cavity exterior of the bone so as to be sutured to the soft tissue.

Abstract: Various exemplary systems and devices for knotless anchor insertion and methods of knotless anchor insertion are provided. In general, an inserter tool is configured for knotless anchor insertion in a soft tissue repair surgical procedure. The inserter tool is configured to insert an anchor into a bone of a patient to secure a soft tissue relative to the bone. A suture coupled to the soft tissue is secured relative to the bone by being trapped between an exterior surface of the anchor and a bone surface defining a hole in the bone in which the anchor is positioned.

Abstract: Various exemplary systems and devices for knotless anchor insertion and methods of knotless anchor insertion are provided. In general, an inserter tool is configured for knotless anchor insertion in a soft tissue repair surgical procedure. The inserter tool is configured to insert an anchor into a bone of a patient to secure a soft tissue relative to the bone. A suture coupled to the soft tissue is secured relative to the bone by being trapped between an exterior surface of the anchor and a bone surface defining a hole in the bone in which the anchor is positioned.

Abstract: knotless anchor insertion are provided. In general, an inserter tool is configured for knotless anchor insertion in a soft tissue repair surgical procedure. The inserter tool is configured to insert an anchor into a bone of a patient to secure a soft tissue relative to the bone. A suture coupled to the soft tissue is secured relative to the bone by being trapped between an exterior surface of the anchor and a bone surface defining a hole in the bone in which the anchor is positioned.

Abstract: A tissue anchor system includes a fixation device and a tool. The fixation device includes a tab connected to a tissue anchor. The tool includes a shaft connected between a proximal handle portion and a distal tip. The distal tip is configured to limit movement of the fixation device during loading of the tissue anchor.

Abstract: A button inserter and system are disclosed that enable easily and effectively deploying a near bone suture button from the button inserter when implementing the suture button technique. To deploy the near bone button, with a far bone button deployed from the button inserter and against the far bone, the button inserter's handle may be translated away from the deployed far bone button. Translating the handle changes a position of a carriage body within a channel of the handle thereby compressing a spring. Protrusions on the carriage body may be forced through notches in the handle, which thereby alters an orientation of the carriage and releases the compressed spring, which applies force to the carriage body. The combination of force induces the carriage to rotate, which thereby releases the near bone button from the carriage. A free end of suture also releases from the carriage.

Abstract: This invention is directed surgical line fixation devices and kits, and methods for using the same.

Abstract: In one embodiment, an adjustable implant system includes a bone anchor having first and second ends, a bone engagement surface adjacent the first end, and a housing extending between the first and second ends. The adjustable implant system can further include a non-invasively actuatable driving element within the housing and coupled to an adjustment component configured to couple to a flexible elongate tension member which is capable of engaging a patient's soft tissue (e.g., rotator cuff or ACL). Non-invasive actuation of the driving element can cause the adjustment component to change the amount of tension on the flexible elongate tension member and consequently on the patient's soft tissue. The adjustable implant system can include an external adjustment device configured to be placed on or adjacent the patient's skin and comprising at least one energy transferring component configured to energize/actuate the driving element inside the housing of the adjustable implant.

Abstract: Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

Abstract: A new and innovative method of routing a strand of material for creating a self-locking construct that joins two objects is provided. More specifically, the provided routing method includes a crossover point at which the routed strand of material crosses over itself thereby enabling the strand portions routed through one of the objects to travel in a same direction when the self-locking construct is cinched. The strand portions traveling in the same direction generates less friction between the portions than if the portions traveled in opposite directions. Accordingly, the provided routing method helps enable a self-locking construct that generates less friction than typical self-locking constructs, which thereby helps reduce the occurrences of weaknesses in the final self-locking construct. The reduced friction generation also helps increase an ease of use for a user when cinching the self-locking construct.

Abstract: Button-suture assemblies which employ a knotted locking mechanism do not maintain tension when securing bone and tissue fragments. A knotless method and device for maintaining tension and providing precise placement of a button-suture assembly during stabilization procedures comprising a locking pin, which mates with a button creating pinch points with increased surface area through which suture can pass from a baseplate through two dedicated openings in the button, one for the first end of the suture and one for the second end of the suture while preventing tension loss during the locking step and therefore allowing for precise placement of the button-suture assembly.

Abstract: A method of operating a surgical instrument is disclosed. The surgical instrument includes an electronic system comprising an electric motor coupled to the end effector; a motor controller coupled to the motor; a parameter threshold detection module configured to monitor multiple parameter thresholds; a sensing module configured to sense tissue compression; a processor coupled to the parameter threshold detection module and the motor controller; and a memory coupled to the processor. The memory stores executable instructions that when executed by the processor cause the processor to monitor multiple levels of action thresholds and monitor speed of the motor and increment a drive unit of the motor, sense tissue compression, and provide rate and control feedback to the user of the surgical instrument.

Abstract: Articulation joints for use in connection with a surgical instrument that has a portion that must be passed through a trocar or similar structure and then articulated relative to another portion of the instrument received within the trocar. Various embodiments of the articulation joint include at least one flexible driven member to articulate the surgical implement relative to the handle assembly of the instrument.

Abstract: A staple for attaching a sheet-like implant to tissue or bone may include first and second arms, and first and second flukes. In some embodiments, the first arm has a proximal end and a distal end, and the second arm has a proximal end and a distal end. A bridge extends from the proximal end of the first arm to the proximal end of the second arm. The first fluke has a proximal end abutting the distal end of the first arm, and the first fluke extends distally from the first arm. The first fluke has a lateral extent larger than a lateral extent of the first arm and is mounted eccentrically thereto. The first fluke includes a proximal surface projecting at an outward angle in a proximal direction away from the distal end of the first arm to engage the tissue or bone when inserted therein. The second fluke has similar features. This arrangement causes the first and second flukes to rotate in response to a pullout force on the bridge.

Abstract: A thread lift cannula has a plurality of therapeutic liquid discharge ports to enable the discharge of a therapeutic liquid into the surrounding tissue. The therapeutic liquid may be injected into the thread lift cannula conduit by a syringe and the thread therein may be bioresorbable and absorb the therapeutic liquid. The therapeutic liquid may include a medicament to reduce swelling or to treat pain, or a biologic that aids in collagen creation, formation, or restructuring. The plurality of therapeutic liquid discharge ports may vary in size along the length of the cannula. A distal discharge port may be larger than a proximal discharge port to enable a more uniform delivery of therapeutic liquid along the cannula. A therapeutic liquid discharge port may be configured at a port angle, offset from orthogonally through the wall of the cannula, to prevent blockage of the outlet opening of the discharge port.

Abstract: Suture passer systems for tissue suspension and tissue compression are described. The system can include a shaft and a needle, wherein the needle is freely rotatable with respect to the shaft. The suture may include an overmolded segment. Methods of placing one or more implants, sutures, fastener, bone anchors and other devices are also described. The methods include moving tissue, including the superior pharyngeal constrictor muscle, palatopharyngeal arch, and palatoglossal arch. The methods include hyoid bone suspension.

Abstract: An endoscopic surgical instrument has a distal end configured to perform an action on tissue; a proximal end; a beam; a drive rod; and at least one rail supporting at least one bearing, the at least one bearing movable relative to the at least one rail. The distal end of the instrument is configured to receive at least a portion of the beam, the beam movable longitudinally in response to an action on the drive rod. The at least one rail is shaped and configured to contact the beam tangentially to prevent the beam from buckling as the beam is moved longitudinally.

Abstract: An anchor-handling device comprises a housing shaped to define a channel having an anchor-storage zone and a proximal opening. An anchor driver comprises an anchor-engaging head, the anchor-engaging head being dimensioned to be advanceable through the proximal opening toward the anchor-storage zone. A tissue anchor is stored in the anchor-storage zone, and comprises a coupling head configured to be locked to the anchor-engaging head. The tissue anchor is movable out of the anchor-storage zone toward the proximal opening in response to a proximally-directed force being applied to the tissue anchor by the anchor driver. The anchor-handling device comprises an element that serves as an indicator of movement of the tissue anchor out of the anchor-storage zone toward the proximal opening, by moving in response to the proximally-directed force such that at least part of the element protrudes out of the housing. Other embodiments are also described.

Abstract: Methods and devices for increasing oxygenation levels in the blood supply and thereby treating the condition of hypoxemia. Multiple approaches such as pressure reduction in the pulmonary circulatory system, reducing triggering mechanisms in the main pulmonary artery and restricting flow in the pulmonary circulatory system are disclosed. Interventions associated with those approaches can including shunting, restrictors, compliance devices, pharmacologic substances, etc.

Abstract: A dual-motor clip applicator includes a working head, and a first motor, a second motor, a first driving assembly, a second driving assembly and a clip cartridge assembly that are provided in the working head. The clip cartridge assembly includes a clip cartridge configured to accommodate a ligation clip and a clip jaw provided on a side of the clip cartridge; the working head further includes a firing rod and a clip-pushing rod, the firing rod is connected to the clip jaw to drive the clip jaw to open or close for firing the ligation clip, the first driving assembly is respectively connected to the firing rod and the first motor, the second driving assembly is respectively connected to the clip-pushing rod and the second motor, and the clip-pushing rod is configured to push the ligation clip in the clip cartridge to enter into the clip jaw.

Abstract: A medical apparatus, including a clamp, a work head and a handle. The work head is connected to the clamp and the handle and includes: a casing, a firing forcing member, a firing rod connected to the firing forcing member, a receiving cavity arranged at a side of the firing rod, and a clip-cartridge assembly; the clip-cartridge assembly being arranged in the receiving cavity and configured for delivering ligation clips to the clamp. An inner cavity communicating with the receiving cavity is formed in the casing. The firing rod is connected to the firing forcing member and the clamp respectively, and the firing forcing member drives the firing rod to move so as to open or close the clamp. The medical apparatus further includes a limiting member, the limiting member being configured for preventing at least one of the clip-cartridge assembly and/or a driving assembly from exceeding a stroke range.

Abstract: An electrolytic detachment mechanism and an electrolytic detachment device are disclosed. The electrolytic detachment mechanism is intended for cooperation with an electrolytic detachment apparatus to achieve an electrolytic detachment of an implant. The electrolytic detachment mechanism includes the implant, a detachment member (103), an electrical conduction member (101) and an absorption member (102). When absorbing electrolytes, the absorption member (102) will maintain electrical conduction between the detachment member (103) and a cathodic conductive element, thus resulting in enhanced electrolytic detachment reliability and overcoming the problems of a long detachment time and required multiple detachment attempts associated with existing electrolytic detachment devices.

Abstract: A medical apparatus, including: a clamp, a work head, and a handle; herein, the work head is connected to the clamp and the handle; the work head includes a casing, a firing forcing member arranged in the casing, a firing rod connected to the firing forcing member, a receiving cavity arranged at a side of the firing rod, and a clip-cartridge assembly configured for delivering ligation clips to the clamp; the firing rod is connected to the firing forcing member and the clamp respectively, and the firing forcing member drives the firing rod to move so as to open or close the clamp; an inner cavity communicating with the receiving cavity is formed in the casing, the casing has an opening formed at a side of the inner cavity, and the clip-cartridge assembly passes through the inner cavity via the opening to be inserted into the receiving cavity.

Abstract: Systems and methods for blood flow control are described herein. In some variations, a blood flow control system may comprise a blood flow control device. The blood flow control device may be placed within a body of a patient and may comprise an expandable member and a sensor. The sensor may be configured to measure at least one of a physiologic condition of the patient and a pressure associated with the expandable member. The blood flow control system may include at least one controller communicably coupled to the sensor to: receive data indicative of at least one of the physiologic condition of the patient and the pressure associated with the expandable member from the sensor, compare the received data with target data, identify at least one error based on the comparison, and in response to identifying the error, inhibit at least one function of the blood flow control system.

Abstract: A method includes indwelling a filter inside a body lumen in a living body so that the filter is indwelled at a position downstream from a stenosed site in the body lumen, moving a collection device in a downstream direction within the living body from upstream of the stenosed site to the stenosed site while the filter remains indwelled at the position downstream from the stenosed site, engaging the filter with the collection device while the filter is indwelled at the position downstream from the stenosed site so that the filter is connected to the collection device, and removing the collection device and the filter from the living body by moving both the filter and the collection device in an upstream direction while the filter and the collection device are engaged with one another.

Abstract: A double layered braid for treating an aneurysm is provided. The braid can include a first radially expandable segment having a first plurality of wire segments with a first braid wire diameter. The braid can include a second radially expandable segment having a second plurality of wire segments with a second braid wire diameter, the second braid wire diameter being greater than the first braid wire diameter. The first segment can radially expand to form an outer occlusive sack that seals across a neck of the aneurysm. The second segment can radially expand within the outer occlusive sack to form an inner occlusive sack. The greater second braid wire diameter can allow the inner occlusive sack to exert a force against the outer occlusive sack and the walls of the aneurysm. The force can minimize movement of the outer occlusive sack from the neck of the aneurysm.

Abstract: An embolic coil implant having a stretch resistant fiber therethrough and dual-functional engagement feature at its proximal end is provided. The stretch resistant fiber can be effective to limiting separation of windings of the embolic coil. The engagement feature can provide an attachment for securing the embolic coil to an engagement system of a delivery tube and for securing the stretch resistant fiber at the proximal end of the embolic coil. The engagement feature can have two engagement surfaces affixed to a proximal end of the embolic coil that are longitudinally offset from each other by a distance that is about half of a diameter of a wire of the embolic coil.

Abstract: An embolization device and a coil thereof (10, 20, 30) are disclosed. The coil (10, 20, 30) is formed by joining together at least four structural elements arranged in different planes, which include at least two C-shaped elements (12) and at least one O-shaped element (13) or ?-shaped (11) element. The at least two C-shaped elements (12) are arranged in two adjacent planes and are sequentially joined together to form an S-shaped structure. The embolization device preferably includes plurality of coils (10, 20, 30) which are joined together side-by-side and end-to-end, wherein in any adjacent two coils (10, 20, 30), one is swivelable about an axis of the embolization device with respect to the other. The ?-shaped element is structurally stable, allowing the coil (10, 20, 30) to maintain good structural stability. At the same time, the three-dimensional S-shaped structure has good deflectability, which imparts high compliance to the coil (10, 20, 30).

Abstract: Intrasaccular flow diverter including: an interior fill braid physically inverted over itself forming a proximal inverted end and an opposite free end; and a dome braid disposed distally of and secured to the interior fill braid. Subject to application of an external mechanical force, the dome braid is transitionable between an expanded state and a compressed state. The dome braid has a proximal end with an opening defined therein through which starting at the free end the interior fill braid is passable therethrough exerting a radially outward force on the dome braid. A delivery wire is releasably detachable from the proximal inverted end of the interior fill braid. The dome braid has a stiffer profile relative to that of the interior fill braid to maintain in position within the aneurysm the dome braid as the interior fill braid is advanced therein.

Abstract: Vascular expandable devices and associated methods are disclosed herein. An expandable vascular device can include a generally tubular sidewall formed of a plurality of braided strands. The device can have a compressed state for delivery in which the device has a compressed state diameter of 0.027 inches or less. The device can have an expanded state in which the device has an expanded state diameter. A full expansion distance of the device corresponds to a longitudinal unconstrained distance at which the distal end of the expandable device attains the expanded state diameter. The full expansion distance can be 20 mm or less.

Abstract: A surgical rongeur device has an interchangeable, locking tip at a cutting end for engageable replacement with a variety of cutting tips for facilitating sterilization and blade changes. A detachable linkage between a handle portion and an interchangeable cutting tip (tip) provides a strong connection for actuation by the handle end but allowing for tip replacement via slidable, lateral displacement of the tip. The tip includes a blade and footplate formed from an amorphous metal for longevity and strength advantages. A handle provides a lever to actuate the tip from slidable communication via the detachable linkage. An interlocking member extends longitudinally from the handle into an internal slot on the tip for locking the tip by preventing lateral movement out of alignment with the handle. The aligned tip is responsive to actuation from the handle via a rail for disposing the blade longitudinally against the footplate.

Abstract: A surgical system including a surgical tool and a navigation system for tracking the position of the surgical tool. The surgical tool comprising a housing including a variable speed motor and control module disposed within the housing. The navigation system comprising a navigation console in communication with the control module of the surgical tool, the navigation console may be configured to communicate instructions to the control module of the surgical tool based on the position of the surgical tool relative to a defined zone. The navigation console may be configured to deactivate the surgical tool based on the position of the surgical tool relative to the defined zone. The navigation console may also be configured to provide a user-selectable override option to allow continued operation of the surgical tool within the defined zone.

Abstract: Surgical drill guides having a guide shaft and a set of distal guide teeth extending from the guide shaft. The guide shaft has proximal and distal portions having two distinct inner and outer diameters, with a tapered zone extending between the two portions. Wall thickness is maintained or increased from the proximal portion to the distal portion of the shaft, reinforcing the rigidity of both the shaft and the distal guide teeth.

Abstract: A catheter, a kit and a method of using the catheter for removing a thrombus from a blood vessel in a mammal. The catheter includes a tubular body with a hollow interior, an exterior surface, a proximal end, and a distal end and a plurality of protrusions extending upwardly from the exterior surface, wherein each protrusion has an aperture. The distal end of the catheter is inserted into the blood vessel and a suction is applied to the proximal end of the catheter to aspirate the thrombus from the blood vessel. The kit includes the catheter, a suction device and a mechanism for controlling the suction flow.

Abstract: Described are methods, systems, devices for facilitation of intraluminal medical procedures within the neurovasculature. A catheter advancement device includes a flexible elongate body having a proximal end, a distal end, and a single lumen extending therebetween. The flexible elongate body has a proximal segment, an intermediate segment, and a tip segment. The proximal segment includes a hypotube coated with a polymer. The intermediate segment includes an unreinforced polymer having a durometer of no more than 72D. The tip segment is formed of a polymer different from the intermediate segment and has a durometer of no more than about 35D and a length of at least 5 cm. The tip segment has a tapered portion that tapers distally from a first outer diameter to a second outer diameter over a length of between 1 and 3 cm.

Abstract: A medical device includes a handle with a proximal arm and a distal arm. The proximal arm and the distal arm are pivotable via a joint. The medical device also includes a tube coupled to the distal arm and a drive wire. A distal portion of the drive wire includes an expandable end effector. A portion of the drive wire is positioned within the tube, and a different portion of the drive wire extends proximally of the distal arm and is coupled to the proximal arm.

Abstract: A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

Abstract: An apparatus for generating focused shockwaves and ultrasound waves comprises a concave reflector holding a cylindrical coil at its center axis. A power generator comprising a combined shockwave and ultrasound generator device is connected to the coil for alternatingly providing an ultrasound signal and a shockwave signal to the coil such that the coil alternatingly generates ultrasound waves and shockwaves.

Abstract: A surgical system includes a stimulation generator, at least one sensor disposed at a working end of a surgical instrument, and a controller coupled to the at least one sensor. The controller is configured to obtain data from the at least one sensor over time in response to a stimulation applied by the stimulation generator, analyze the data obtained from the at least one sensor over time to generate sensor data analysis results, apply a signal processing method and/or a pattern matching to the sensor data analysis results, and indicate if a tissue or artifact is present within a region proximate to the working end of the surgical instrument based on the signal processing method or pattern matching.

Abstract: In order to easily and stably adhere an adhering body by suction to an easily deformable flexible object, the adhering body includes an elastically deformable body that moves back and forth between a closing position at which the elastically deformable body closes a communication port and an opening position at which the elastically deformable body opens the communication port, the elastically deformable body moving, in conjunction with movement of a movable contact part to a retreat position, so as to open the communication port.

Abstract: Devices and methods for performing subcutaneous surgery in a minimally invasive manner are provided. The methods include application of reduced air pressure in a recessed area of a handpiece placed over a section of skin and drawing the section of skin and subcutaneous tissue into the recessed area. In a subsequent step a tool is inserted through a tool conduit in the handpiece and through the skin into the subcutaneous tissue, enabling the performance of the desired surgery. Common surgical procedures include dissection and ablation . The devices and methods can be directed at the treatment of skin conditions like atrophic scars, wrinkles, or other cosmetic issues, at treatments like or promoting wound healing or preventing hyperhidrosis, or can be used for creating space for various implants.

Abstract: A waterjet necrosectomy device for providing a controllable waterjet force capable of fragmenting necrosis without damage to healthy tissue. The device includes a housing having an actuator and a connector coupled to the housing. The connector includes a first channel and a second channel. The device also includes a length of tubing coupled to the connector, a nozzle coupled to the tubing, and a wire extending through the housing, the connector, and the tubing, the wire being configured to articulate the nozzle upon movement of the actuator.