Abstract: A ventilator comprising a respiratory gas source and control systems, a housing with a receptacle and, lying at the base in a depression, an interface for receiving different data transfer sticks and data storage sticks.

Abstract: Various embodiments are directed to a method for operating a blower so as to generate an at least substantially consistent output flowrate comprising programmatically determining an optimized motor speed based at least in part on blower motor data and a blower characterization curve, wherein the blower characterization curve defines a correlation between motor speed and motor voltage of a blower motor configured to generate a desired respirator output flowrate; and programmatically adjusting a motor voltage based at least in part on a comparison of measured motor speed data to the optimized motor speed, wherein the blower characterization curve is defined by one or more blower characterization equations derived based at least in part on a plurality of motor output calibration points. Various embodiments are directed to a respirator apparatus configured to generate an at least substantially consistent respirator output airflow.

Abstract: A sanitary extubation cover used to cover an endotracheal tube and a patient's face in order to accommodate sanitary extubation. The sanitary extubation cover includes a mask and a cover which covers the endotracheal tube. If the patient coughs, the cough would be directed into the mask and the endotracheal tube (which is covered by the cover) but contaminants from the cough would be suppressed from spreading into the open air.

Abstract: A connector a medication dispenser includes a first portion coupling the connector to the medication dispenser and a second portion configured to couple the connector to a breathing apparatus. The first portion has a first opening with a first shape and a first size. The second portion has a second opening with a second shape and a second size that are different from the first shape and the first size of the first opening, respectively.

Abstract: A sealing arrangement for forming a seal between a patient's face and a patient interface device for use in delivering a flow of a treatment gas to the patient includes a generally planar substrate body having a first side and an opposite second side. The substrate body includes a main portion having an opening defined therethrough that is sized and configured to encompass the mouth and nose of the patient. The sealing arrangement further includes a first adhesive layer disposed on the first side of the substrate body and a second adhesive layer disposed on the second side of the substrate body. The first adhesive layer is sized and configured to adhere to the skin of the patient with a first adherence force and the second adhesive layer is sized and configured to adhere to a cushion of the patient interface device with a lesser second adherence force.

Abstract: A device for providing a known concentration of blended air and oxygen, or oxygen, to an individual which incorporates a face mask inside a hood, thereby preventing aerosolization of potentially harmful exhaled gases and controlling condensation issues within the hood while under pressurized conditions. The air tight seal required to allow placement and removal of the hood on the individual will be manufactured using injection molded elastomers to over-mold injection molded rigid plastic components.

Abstract: This invention relates to a patient interface, such as a nasal cannula, comprising a body to be positioned upon a user (preferably such as a user's face), the body including at least one (and preferably a pair of) nasal prong(s), the or each nasal prong including a lumen capable of being fluidly connected thereto for fluid communication with a supply of breathable gas, the or each nasal prong to be in a configuration either inserted into, or to direct a flow of gas toward, a nare or the nares of the user's nose, wherein the body includes at least one element responsive to force(s) or movement(s), or both, experienced by at least a first region of the patient interface.

Abstract: A patient interface, such as a nasal cannula is described. The patient interface has a body portion to be located, in-use upon a face of a user. The body portion has at least one side arm that extends laterally from a central bridge portion to be located about a user's septum region, where each side arm is connected to a resilient, or relatively more rigid, bridge portion element. The interface has at least one, and preferably a pair of, nasal prong(s). The body portion has at least one fluid passageway connected to the nasal prong(s) for supply of a gas to the nare(s) of the user's nose. A cross section of the passageway varies along the length of the body portion to regions of varying flexibility along the body portion. The bridge portion element defines a substantially predetermined spatial relationship for outlet(s) of a gas delivery system supplying gas via each side arm to the outlet(s) from which, for example, the nasal prong(s) may be provided in fluid connection.

Abstract: An airway holder for use in holding an airway device, such as an air or nose tube, has a first pair of wings symmetrically disposed about a center portion and a second pair of wings asymmetrically disposed about the center portion. One of the wings of the second pair of wings has an offset to facilitate that wing wrapping about a portion of the other wing of that pair about the airway device, before then, preferably being adhered to the face of the patient. The airway holder may be provided as a portion of a kit with eye protectors in an effort to remove surgical tape (and subsequent reuse with other procedures to potentially spread contamination).

Abstract: A respiratory filter and condensate management apparatus is provided for use in a breathing circuit during patient respiration. The apparatus includes a housing having an air inlet port for receiving a flow of respiratory air, and an air outlet port for outputting the flow of respiratory air to a ventilator. A filter compartment is provided within the housing and includes a filter member located in a flow path of the respiratory air from the air inlet port to the air outlet port. A condensate collection compartment is provided within the housing and includes at least one reservoir and at least one self-sealing drainage port. The reservoir collects liquid formed by condensation of the respiratory air within the filter compartment, and the drainage port allows removal of the collected liquid from the reservoir while the housing remains connected to the breathing circuit.

Abstract: A passive valve for use as a fixed leak valve. The valve includes a body having an internal chamber, first and second body ports in fluid communication with the chamber with the first port configured for fluid communication with a patient connection and the second body port configured for fluid communication with a ventilator, a body passageway in fluid communication with the chamber and with ambient air exterior of the body, and a check valve seal positioned to seal the body passageway to permit the flow of gas within the chamber through the body passageway to the exterior of the body and to prevent the flow of ambient air exterior of the body through the body passageway into the chamber. In alternative embodiments, the valve is incorporated into the patient connection or constructed as a separate part connectable to the patient connection.

Abstract: A breathing apparatus includes a first air pathway for receiving ambient air and channeling the air through a portion of the breathing apparatus, a heating section operatively coupled to the first air pathway and configured to elevate a temperature of the ambient air in the first air pathway to a first prescribed temperature, and a cooling section operatively coupled to the first air pathway and configured to reduce the temperature of the ambient air heated by the heating section to a second prescribed temperature, the second prescribed temperature lower than the first prescribed temperature. A breathing circuit is coupled to the first air pathway and configured to provide the cooled air to a user.

Abstract: An air delivery conduit for use with an apparatus to deliver a supply of pressurized breathable air includes a tube, a first wire, a second wire, a first cuff, and a second cuff. The first wire extends at least partially between a first end and a second end of the tube. The first wire has a first diameter. The second wire extends at least partially between the first end and the second end. The second wire has a second diameter different than the first diameter. The first cuff is coupled to the first end of the tube. The second cuff is coupled to the second end of the tube and includes a thermistor connected to the first wire and a fixture that protrudes from an internal surface of the second cuff into a flow path of the supply of pressurized breathable air. The thermistor is enclosed within the fixture.

Abstract: A nitric oxide administration device 1 includes a first flow path 101 including a first intake port 101a and an oxygen supply port 101b, an oxygen generation unit 100 which is arranged in the first flow path 101 and which generates concentrated oxygen from air introduced via the first intake port 101a, the generated concentrated oxygen being supplied via the oxygen supply port 101b, a second flow path 201 which is branched from the first flow path 101 and which includes an NO supply port 201b, and an NO generation unit 200 which is arranged in the second flow path 201 and which generates NO from gas distributed from the first flow path 101, the generated NO being supplied via the NO supply port 201b.

Abstract: A method of forming a stream having a therapeutic concentration of nitric oxide (NO) is disclosed, along with an apparatus and system suitable to accomplish this method.

Abstract: An apparatus for humidifying a flow of breathable gas includes a water reservoir including a chamber structured to hold a volume of water, a water reservoir dock structured and arranged to receive the water reservoir in an operative position, and a latch movable between (1) a locked position to releasably lock the water reservoir to the water reservoir dock in the operative position, and (2) an unlocked position to allow insertion of the water reservoir into the water reservoir dock and removal of the water reservoir from the water reservoir dock.

Abstract: The design and structure of a fully automatic oxygen therapy apparatus is exhibited in this disclosure. The apparatus integrates a MEMS mass flow meter, an oximeter, a proportional valve and a smart liquid bottle. The control unit of the apparatus is embedded with a wireless communication device and powered by a battery pack. This apparatus is designed to replace the mechanical oxygen rotameter used in today's hospital or homecare oxygen therapy applications. With a set recipe or parameters locally or remotely, the disclosed apparatus can perform a fully automatic oxygen therapy for recovering the blood oxygen level of patient, without the frequent attention of the therapy administrator, and especially it significantly reduces the possibility of cross infection to the administrator during the attendance of the oxygen therapy process. The therapy process data are relayed to local users as well as a designated cloud or data center. This disclosure will be beneficial for both medical staffs and patient.

Abstract: A tuneable expiration positive airway pressure (TEPAP) apparatus (10) comprises an entrainment valve (12) and a module (14), fluidly coupled with an outlet port (60) of the entrainment valve, for tuning an inspiration-to-expiration pressure transition of the breath cycle. The entrainment valve (12) includes a housing (56), an upstream inlet port (58), a downstream outlet port (60), and a valve (62). The valve (62) enables inspiration airflow between an exterior the housing (56) and the inlet port (58) during inspiration and prevents expiration airflow between the inlet port (58) and the exterior of the housing (56) during expiration. The tuning module (14) facilitates at least one rate-of-change in pressure of the inspiration-to-expiration pressure transition that is non-instantaneous. The at least one non-instantaneous rate of change in pressure is selected from among different non-instantaneous rates-of-change in pressure of the inspiration-to-expiration pressure transition.

Abstract: A gas washout vent, and a patient interface with the gas washout vent, configured to allow patient-exhaled CO2 to flow to an exterior of the plenum chamber to minimise rebreathing of exhaled CO2 by the patient, the gas washout vent including at least one outlet orifice; a diffusing member at least partly covering the outlet orifice; and a blocking member having an air-impermeable material, the blocking member preventing gas exiting from the outlet orifice from flowing straight through the diffusing member.

Abstract: The mood adjuster device comprises: a housing; a plurality of detectors or sensors for obtaining information on the physical characteristics of an individual; a plurality of sensory stimulus generators for providing sensory stimulus to the individual; a controller that receives information from the detectors or sensors and analyzes the information to determine a physical treatment; a memory for storing the information received by the plurality of detectors or sensors, the analyzes performed by the controller and the physical treatment as applied by the sensory stimulus generators; a user interface to allow the individual to communicate with the controller; a medical practitioner interface for accessing information stored in the memory or for providing instructions to the controller or to interface directly with the individual; and a power supply.

Abstract: Devices and methods are described that aid in harmonizing a person with their bodies and/or their environment.

Abstract: A vibration control device that while responding to music being played, generates a vibration that gives desired arousal effect and/or relaxing effect regardless of the contents is provided, the vibration control device controlling a vibration device that generates vibration according to the music being played and gives a stimulus to a user includes a vibration signal acquisition unit for acquiring a vibration signal representing the vibration in which a stimulus intensity falls within a predetermined stimulus intensity range, and an output unit for outputting the vibration signal acquired by the vibration signal acquisition unit to the vibration device.

Abstract: The invention provides intravascular devices for treating certain medical conditions such as edema without causing thrombosis. The intravascular devices of the disclosure include non-thrombogenic surfaces that improve blood compatibility by reducing device-related thrombus formation and inflammatory reactions. The non-thrombogenic surfaces may include surface topographies (e.g., surface roughness) and modified chemistries (e.g., coatings and/or treatments), which prevent thrombosis by reducing local shear forces and inhibiting adhesion of blood clotting factors.

Abstract: Methods and devices described for improved dynamic walled tubing and catheters.

Abstract: Embodiments described herein are directed to an apparatus for guiding a catheter and a method of operating the same. The apparatus includes a first portion and a second portion. The first portion has a cylindrical body. The cylindrical body includes a first opening formed therethrough. The opening configured to receive a catheter. The second portion includes a body. The body includes a top surface and a bottom surface. The top surface is substantially parallel to the bottom surface. The bottom surface is configured to contact a skin of a patient. The body includes a second opening formed therethrough. The second portion is coupled with the first portion such that a forty-five degree angle is formed therebetween. The first opening and the second opening form an uninterrupted opening through the apparatus.

Abstract: A method and system of correcting alignment of catheter relative to a target including receiving signals from an inertial measurement unit located at a distal end of a catheter, determining movement of the distal end of the catheter caused by physiological forces, receiving images depicting the distal end of the catheter and the target, identifying the distal end of the catheter and the target in the images, determining an orientation of the distal end of the catheter relative to the target and articulating the distal tip of the catheter in response to the detected movement to achieve and maintain an orientation towards the target such that a tool extended from an opening at the distal end of the catheter would intersect the target.

Abstract: Catheter devices and uses thereof are provided that include inner and outer tubular members, each having proximal and distal ends, where the distal end of the outer tubular member is shaped, including at least one curve, such as a Judkins right curve or an Amplatzer left curve. At least a portion of the inner tubular member is coaxially positioned within the outer tubular member. The control mechanism has a housing with a means to seal an inner luminal space thereof, where the control mechanism is coupled to the proximal ends of the outer tubular member and the inner tubular member. The control mechanism is operable to extend and retract the distal end of the inner tubular member from the shaped distal end of the outer tubular member.

Abstract: A deflectable vascular catheter is disclosed which includes a proximal handle assembly, an elongated sheath extending distally from the proximal handle assembly and including a deflectable distal end portion, an actuation mechanism operatively associated within an interior cavity of the proximal handle assembly for deflecting the distal end portion of the sheath, an anchor ring located at a distal end of the deflectable distal end portion of the sheath, and a pull wire extending from the actuation mechanism to the anchor ring, wherein the pull wire has a non-circular cross-section and is laser welded to an exterior surface of the anchoring ring.

Abstract: Steerable delivery devices use one or more pull wires. Described herein are devices and methods for securing a pull wire to an adjustment mechanism of such delivery devices. The disclosed devices facilitate securing the pull wire by using a wrapping set screw that forms a lumen for the pull wire and one or more notches in the side of the wrapping set screw at its proximal end. The notches allow the pull wire to be pulled through a notch so that when the wrapping set screw is driven into a threaded lumen the pull wire lies along the roots of the screw. The pull wire is secured in place due at least in part to friction and/or to being pressed between the screw and the threaded lumen of a wrap housing where the wrap housing can be part of the adjustment mechanism of the delivery device.

Abstract: A catheter assembly for organizing a catheter system is disclosed. The catheter assembly can include a molded hub, a catheter tube coupled to a distal end of the molded hub, a plurality of extension legs having distal ends coupled to the molded hub, and a securing mechanism. The molded hub can include a pair of hub lumens forming a hub portion of a pair of fluid pathways through the catheter assembly. The catheter tube can include a pair of catheter tube lumens. The securing mechanism can be configured to secure the plurality of extension legs together. The securing mechanism can be in the form of a slidable collar including a proximal opening and distal opening, wherein the slidable collar is positioned over the plurality of extension legs.

Abstract: A catheter assembly includes: an inner needle configured to puncture a living body; a catheter configured to allow the inner needle to be inserted therethrough; a catheter hub located at a proximal end of the catheter; a valve body located in an internal space of the catheter hub; an opening member located on a proximal side of the valve body, the opening member comprising: a cylindrical barrel portion, a neck portion extending from a distal end of the barrel portion, wherein a diameter of the neck portion is smaller than a diameter of the cylindrical barrel portion, and a foot portion extending to a proximal side of the barrel portion, wherein the opening member is configured to move in a distal direction to open the valve body; and a movement inhibiting mechanism that resists movement of the opening member in the distal direction via a contact portion.

Abstract: The present invention relates to peripheral intravenous catheters, and in particular to an integrated peripheral intravenous catheter having a low profile securement platform, a needle hub having an interior compartment and further comprising a paddle grip, and an extension tube coupled to the catheter and stored within the interior compartment of the needle hub prior to catheterization.

Abstract: A catheter system may include a catheter adapter, which may include a body and a nose extending distally from the body. The nose may be generally cylindrical. A strain relief rib may be disposed on the nose. The strain relief rib may be constructed of a flexible material. A bump may be disposed on the strain relief rib and configured to contact a needle cover. A catheter may be secured within the catheter adapter and extend distally beyond the nose.

Abstract: A biomedical pressure sensor for measuring the pressure in a fluid includes an optical fiber having at least one measurement section arranged at a distance from a distal end of the optical fiber. The biomedical pressure sensor further includes a deforming member on the outer surface of the optical fiber at the location of the measurement section that is arranged for locally deforming the optical fiber under the influence of the applied pressure of the fluid to be measured. The measurement section is arranged for measuring said local deformation of the optical fiber.

Abstract: A guidewire made from a drawn-filled tube composite wire is described. The composite wire has a stainless steel outer sheath jacketing a nitinol core wire. The drawn-filled tube composite wire is ground at its distal end to expose the nitinol core, which has superelastic and kink resistant properties that are desirable for the distal end of a guidewire. The proximal end of the drawn-filled tube is not ground or if ground, the outer sheath of stainless steel is not removed to an extent sufficient to expose the nitinol core.

Abstract: An inserter, a medical elongated body set, and a method of using an inserter can effectively remove air remaining inside a distal portion of a medical elongated body by effectively performing priming on the distal portion of the medical elongated body. An inserter assists a medical elongated body to be inserted into a medical device. The inserter includes a tubular portion having a proximal opening portion into which the medical elongated body is inserted and a distal opening portion that guides the medical elongated body to the medical device, and having a main lumen through which the proximal opening portion and the distal opening portion communicate with each other, and a connector that communicates with the main lumen of the tubular portion, and connects a liquid injection tool.

Abstract: A method and apparatus for delivery of cell therapies, introduced via percutaneous access to the circulation, and delivered to the site of vascular injury intervention.

Abstract: A system and method of accurately measuring a pressure (Pp) within a human brain using totally-implanted or partially-external hardware. The system includes a first pressure transducer configured to measure a cerebrospinal fluid pressure (Pcsf) within a ventricle of a brain, a second pressure transducer configured to indirectly measure a second pressure (Pp) within a space of the brain, and an adjustable implanted valve controller configured to calculate the effective differential pressure (Pei=Pcsf?Pp) between the measured pressures Pcsf and the Pp and determine whether the effective differential pressure measurement represents a true secondary pressure.

Abstract: An implantable intracranial pulse pressure modulator for treating hydrocephalus in patients of all ages is disclosed as well as a system and method for use of the same. In one embodiment of the implantable intracranial pulse pressure modulator, two one-way valves are interposed in parallel, opposing orientations between a vestibule and a chamber. One of the one-way valves, in response to systole, provides fluid communication from the vestibule to the chamber such that a small aliquot of cerebrospinal fluid (CSF) is displaced from a cerebral ventricle into a ventricular catheter, thereby reducing intraventricular systolic pressure. The other one-way valve, in response to diastole, provides fluid communication from the chamber to the vestibule such that the same volume of CSF is reintroduced into a cerebral ventricle, thereby increasing intraventricular diastolic pressure. Together, both processes work synergistically to reduce intraventricular pulse pressure in order to treat hydrocephalus.

Abstract: An indwelling device for treating flora includes probiotics, a carrier carrying the probiotics and including a first region arranged in an appendico and a second region arranged in an intestinal cecum, in which the probiotics are carried in the first region and the second region contains an antibacterial agent.

Abstract: The present specification disclosed a noninvasive transdermal delivery device that relates generally to a handheld mechanical apparatus for noninvasive transdermal administration of gas, small to large water-soluble (hydrophilic) pharmaceutical agents, vitamins, and other therapeutic agents. Components of such delivery devices, methods of producing a substance comprising a supersaturated amount of a dissolved gas, as well as, methods of administering a therapeutic agent using such delivery devices and methods of treating a disease or condition using such delivery devices are also disclosed.

Abstract: A device for inserting needles of a microneedle patch into a skin includes a housing. The housing includes a support portion for supporting a microneedle patch, a pressure-receiving portion to which the user applies a force to press the microneedle patch against the skin, and a plurality of leg portions each having at its one end a connecting portion connected to the pressure-receiving portion and having at its other end a tip portion coming into contact with the skin. The housing is designed to deform when a force is applied to the pressure-receiving portion, to cause a tension in a portion of the skin facing the support portion.

Abstract: A tattoo device according to the present invention comprises a body including a hollow penetrating in the longitudinal direction; a compression ring coupled to the front end of the body; a chuck comprising a plurality of elastic support parts disposed in the body, a plurality of pressing parts extending from one ends of each elastic support parts and at least partly disposed in the compression ring, and a connection part combining the other ends of elastic support parts; a push member comprising a shaft part and a button part, the shaft part disposed in the body and coupled to the connection part of the chuck, the button part extending from the shaft part and at least partly protruding outside of rear end of the body; and a spring disposed in the body and providing an elastic force to push the push member toward the rear end of the body. A gap between the plurality of pressing parts may be widened when the push member is pushed toward the front end of the body.

Abstract: A device for intravascular intervention can comprise an interventional element, an elongate manipulation member having a retention portion, and a joining element. The elongate element can comprise a distally located attachment portion. The interventional element includes a proximal end portion with a hole therethrough, the attachment portion of the elongate member extending through the hole at the bend such that first and second segments of the elongate member each extend proximally from the hole. A retention portion includes an arm extends proximally of the hole and a shoulder protruding radially outwardly from a proximal portion of the arm. A joining element circumferentially surrounds at least a portion of the retention portion and at least a portion of the first and second segments of the elongate member such that a proximal end of the joining element is positioned distal to the shoulder of the retention portion.

Abstract: A pressure relief valve for a reservoir has a main body with a central chamber defining an outer radial seat, a positive-pressure port with an inner radial seat, and a negative-pressure port comprising an internal passage spanning the outer seat. The sealing disk has an anchor body retained in the central chamber and a flexible diaphragm biased against the outer seat. An axial passage in the anchor body couples the central chamber to ambient atmospheric pressure. The sealing ball is biased against the inner seat. When a pressure inside the reservoir exceeds ambient by a positive-pressure threshold, then the sealing ball lifts off the inner radial seat to exhaust a gas through the positive-pressure port. When the pressure inside the reservoir is below ambient by a negative-pressure threshold, then the diaphragm is lifted off the outer seat to intake atmospheric gas into the reservoir.

Abstract: A cardiac support system (20) is equipped with a retaining structure (30) for the cardiac support system, said retaining structure (30) being intended to fix the cardiac support system in place. The cardiac support system comprises a device for monitoring the integrity of the retaining structure (30).

Abstract: An implantable cardiovascular blood pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable cardiovascular pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable cardiovascular pump. The implantable cardiovascular blood pump includes a coaxial inflow cannula and outflow cannula in fluid communication with one another and with a pumping mechanism. The pumping mechanism may be a vibrating membrane pump which may include a flexible membrane coupled to an electromagnetic actuator assembly that causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable cardiovascular pump.

Abstract: A system for providing ventricular assistance to a heart of a subject, the system including a balloon configured to be inserted into a ventricle of the heart, wherein the balloon is configured to differentially inflate to thereby urge blood towards a semilunar valve of the ventricle; a fluid conduit in fluid communication with the balloon; a pumping mechanism attached to the fluid conduit; and, a controller configured to control the pumping mechanism to thereby selectively supply fluid into the balloon so as to inflate the balloon at least partially in accordance with the cardiac cycle.

Abstract: The invention relates to an impeller housing (1) for an implantable, vascular support system (2), at least comprising: an impeller housing body (3) having a first longitudinal portion (4) and a second longitudinal portion (5); at least one holder (8), which is disposed in the first longitudinal portion (4), wherein the holder (8) is configured such that it can hold a bearing (6) for rotatably mounting an impeller (9) in the center of a cross-section of the impeller housing body (3) through which a fluid can flow, at least one opening (7) through which liquid can flow and which is disposed in the second longitudinal portion (5) and in a lateral surface of the impeller housing body (3).

Abstract: The present invention provides a direct cardiac compression device for individualized support at different locations around the heart, the device comprising: a housing shaped to conform to the shape of the heart and to surround the heart; two or more active chambers positioned adjacent to the housing, wherein the two or more active comprise one or more right active chambers positioned on the right ventricle side of the heart and one or more left active chambers positioned on the left ventricle side of the heart, wherein the two or more active chambers are designed to conform to the shape of the heart, each active chamber comprising an inner membrane sealingly attached along its periphery to the housing and an active fluid individually supplied thereto; a right input connection in fluid communication with the one or more right active chambers to ingress the active fluid into each of the one or more right active chambers; a left input connection in fluid communication with the one or more left active chambers t