Abstract: An arterial flow measurement system comprising: a catheter tube being which may be configured to be inserted into an artery, the catheter tube having longitudinal axis, a proximal end and a distal end, a first inner lumen providing fluid communication along the longitudinal axis of the catheter tube, a first opening (input opening) configured to provide fluid communication from the outside of the catheter tube and into the first inner lumen through a side wall of the catheter tube, a fluid guide element having an insertion state where the fluid guide element has a first cross-sectional diameter, and in a measuring state where the fluid guide element has a second-cross-sectional diameter, where the fluid guide element is configured to guide at least part of an arterial flow surrounding the fluid guide element into the first opening, a conversion element, where the conversion element is connected to the fluid guide element allowing a user to selectively transform the fluid guide element from an insertion state

Abstract: A pressure guidewire is provided that has a proximal end and a distal end. The pressure guidewire has a proximal section a sensor housing section, and an intermediate section. The proximal section extends from the proximal end of the pressure guidewire to a distal end of the proximal section. The sensor housing section is disposed adjacent to the distal end of the pressure guidewire. The intermediate section disposed between the proximal section and the sensor housing section. The intermediate section has a proximal end separate from the proximal section. The proximal end can be coupled to the distal end of the proximal section. The pressure guidewire has a tubular body positioned within the intermediate section.

Abstract: An adaptive processing of the pulsatility signal can improve the pulse wave analysis (PWA) leading to a better blood pressure estimation. The technique is based on transforming the pulsatility signal so that the fiducial points required for the PWA are well-defined.

Abstract: Some disclosed methods involve controlling, via a control system, a light source system to emit a plurality of light pulses into biological tissue at a pulse repetition frequency, the biological tissue including blood and blood vessels at depths within the biological tissue. Such methods may involve receiving, by the control system, signals from the piezoelectric receiver corresponding to acoustic waves emitted from portions of the biological tissue, the acoustic waves corresponding to photoacoustic emissions from the blood and the blood vessels caused by the plurality of light pulses. Such methods may involve detecting, by the control system, heart rate waveforms in the signals, determining, by the control system, a first subset of detected heart rate waveforms corresponding to vein heart rate waveforms and determining, by the control system, a second subset of detected heart rate waveforms corresponding to artery heart rate waveforms.

Abstract: A biological characteristic information detection device and an electronic device are provided. The detection device includes: a pressure detection module including a cantilever beam and a pressure sensor, where the pressure sensor is fixed on a surface of the cantilever beam, the cantilever beam includes an elastic arm and a fixed base, the fixed base is fixed in the electronic device, and the elastic arm is suspended in the air; and a PPG detection module arranged on the elastic arm and configured to detect a PPG signal of a user when the user presses the electronic device, where when the user presses the electronic device, a pressure signal applied to the electronic device is transmitted to the cantilever beam through the PPG detection module, so that the pressure sensor detects the pressure signal, and the pressure signal and the PPG signal are used to detect biological characteristic information.

Abstract: The present invention relates to the field of cardiac disease, in particular to the assessment of coronary vessels, in particular to determine the mechanisms and patterns of blockage or restriction to the blood flow through a coronary vessel. The present invention provides diagnostic methods and devices to determine the condition of coronary artery disease, in specific to determine the functional pattern (focal or diffuse) of coronary artery disease.

Abstract: A blood pressure detection method, an apparatus, and an electronic device are provided, having relatively accurate blood pressure detection results and are convenient to detect. The blood pressure detection method is applied to a blood pressure detection apparatus, and the method includes: acquiring blood pressure calibration information, the blood pressure calibration information being information obtained by processing according to a first pressure acting on a user and a first PPG signal when the first pressure acts on the user; acquiring a second PPG signal, and processing according to the second PPG signal to obtain the user's initial blood pressure; and calibrating the initial blood pressure according to the blood pressure calibration information, and using the blood pressure obtained by calibration as the blood pressure of the user. In this technical solution, there is no need to resort to an external device such as a blood pressure meter for assistance.

Abstract: A detection device of a body-worn device including a back cover provided with a protective glass that is a light transmissive transparent section, a holder attached to the back cover and positioned opposing the protective glass, a circuit board arranged between the back cover and the holder, an optical sensor provided on the undersurface of the circuit board opposing the protective glass so as to detect light, and energizing members arranged between the holder and the circuit board so as to force the circuit board and the optical sensor toward the protective glass. By being forced toward the protective glass by the energizing members, the circuit board reliably and favorably presses the optical sensor against the protective glass, whereby the optical sensor reliably and favorably comes in close contact with the protective glass in a stable state.

Abstract: Embodiments generally relate to a device for monitoring air pressure in the body of a patient. The device comprises a tube comprising a feeding lumen; a sensor lumen positioned parallel to the feeding lumen; at least one sensor positioned in the sensor lumen; and at least one perforation positioned to expose the at least one sensor to an air pressure within the body of a patient when the device is positioned at least partially in the airway of the patient. The at least one sensor is configured to generate data related to the pressure to which the sensor has been exposed.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.

Abstract: A system for monitoring a patient during MRI imaging to prevent patient burns. The system includes a barrel to provide an MRI image of a patient and an infrared camera to image the patient separately from the MRI image. The infrared camera includes an adjustable field of view and is positionable at a plurality of viewing angles relative to the longitudinal axis of the barrel. The infrared camera is coupled to a processor adapted to monitor the surface temperature of the patient based on the output of the infrared camera. The processor is further adapted to control at least one of the field of view of the infrared camera and/or the viewing angle of the camera during MRI imaging of the patient. The system further includes a patient gown formed of an infrared transmissive material that provides visual concealment for the patient.

Abstract: The present invention relates to an inductive plethysmography vest for a mammal having a mass less than 6 kg, comprising: a tube (10) made of elastic textile configured to surround the trunk of said mammal, said tube (10) extending along a longitudinal axis (X) parallel to the spinal column of said mammal; at least one inductive winding formed of a strand (20) of electrically conductive wire arranged in the form of wavelets along the circumference of said tube (10); said vest being characterised in that it comprises at least one strip (11) made of elastic textile, arranged along the circumference of the tube, defining a plurality of longitudinal loops (111), each wavelet being formed by the passage of the strand (20) of conductive wire successively in each loop (111).

Abstract: Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements.

Abstract: A lesion characterization process is disclosed. According to one aspect, a method includes obtaining measurements of at least one of an impedance magnitude, impedance phase, a temperature, and electrical properties of tissue of the lesion. The method further includes determining at least one lesion property including at least one of a depth of the lesion, percent transmurality of the lesion, lesion surface area and lesion volume based on at least one of the obtained measurements.

Abstract: Systems and methods for locating a medical device in a body lumen are provided. A first flexible elongate instrument comprises a plurality of imaging markers, and a location information sensor is disposed at the first flexible elongate instrument or at a second flexible elongate instrument configured for relative movement with respect to the first flexible elongate instrument. A processor is configured to establish a reference coordinate system based on the plurality of imaging markers, which are visible in a medical image comprising the first flexible elongate instrument disposed in a body lumen, receive diagnostic scan or therapeutic delivery information at a plurality of locations of the body lumen from the first or second flexible elongate instrument, and correlate the information with the imaging markers. A display configured to display a composite image comprising the correlated diagnostic scan or therapeutic delivery information and the imaging markers.

Abstract: This apparatus produces a capnogram for a patient, comprising airflow means arrangeable such that air flowing into and out of a patient during a breathing cycle of the patient are conducted through the airflow means; a CO2 monitor (50) for repeatedly determining the presence, and level, of CO2 in the air within the airflow means; an airflow direction sensor for distinguishing between periods when air is flowing into the patient, when air is flowing out of the patient, and when air in the airflow means is stationary; a processor for producing a graph on a display of time versus an indication of CO2 levels, wherein the display includes different graphical qualities to distinguish between the level of CO2 in the air flowing out of the patient, the level of CO2 in the stationary air between breaths, and the level of CO2 in the air flowing into the patient.

Abstract: A system for measuring a mass of exhaled carbon for weight loss monitoring. The system includes a capture device for capturing exhaled breath and determining a mass of carbon in the exhaled breath, a respiratory inductive plethysmograph (RIP) device incorporated into apparel, and a processor incorporated into a computing device. Mass of exhaled carbon may be determined by the capture device and computing device alone. Alternatively, mass of exhaled carbon may be determined by the RIP device and the computing device alone, after calibration of the RIP device using the capture device.

Abstract: In one embodiment, the present invention provides a biological sample capture device comprising a body including a chamber, the chamber being arranged to sealingly hold a biological sample, a first valve in communication with the chamber, wherein the first valve allows a biological sample to enter the chamber, a second valve in communication with the chamber, wherein the second valve is arranged to expel air from the chamber upon a biological sample entering the chamber via the first valve.

Abstract: Provided is an information processing device including an action information acquisition unit configured to acquire action information of a user, a pedaling period extracting unit configured to extract a plurality of pedaling periods during which the user pedals a bicycle from the action information, and a calculation unit configured to calculate a non-pedaling time during which the user is on the bicycle and does not pedal based on a start time of each of the plurality of pedaling periods and an end time of each of the plurality of pedaling periods.

Abstract: Provided is an information processing device including an acquisition unit configured to acquire first load information measured by a first load measurement device provided on a sole of a user and second load information measured by a second load measurement device provided to be closer to a toe of the sole than the first load measurement device and a determination unit configured to determine whether or not the user is in a pedaling state in which the user pedals a bicycle based on the first load information and the second load information.

Abstract: A lower limb rehabilitation system based on augmented reality and a brain computer interface includes a display, a plurality of motion sensors, a brain wave monitor, and an analysis platform. The display is configured to receive and play a virtual scene video to guide a user to perform gait rehabilitation training. The plurality of motion sensors is configured to sense gait data. The brain wave monitor is configured to record an electroencephalogram signal by detecting an electric current change in a brain wave of the user. The analysis platform is configured to compare the gait data with the virtual scene video to determine the accuracy of footsteps of the user and provide feedback. The analysis platform inputs the electroencephalogram signal to a machine learning model to quantify the electroencephalogram signal into an index value representing a lower limb motor function of the user.

Abstract: A recommendation system may store user data, fitness class data, and expert rules data. The user data may correspond to health or fitness information about a user. The fitness class data may correspond to information about a fitness class. The expert rules data may correspond to an action for accomplishing a health objective. The recommendation system may be configured to determine health objective data based on the user data. The health objective data may be determined directly or inferentially. The health objective data may be matched with the expert rules data. The expert rules data may be matched with the fitness class data. The fitness class data may correspond to an aspect of the fitness class that aligns with the health objective of the user. Recommendation data may be generated that corresponds to a recommendation of the fitness class for the user.

Abstract: The invention discloses a parametric system for testing a capability of auditory spatial positioning and a method of providing a parametric minimum audible angle. The system includes: an host computer system calculating spatial movement data and communicating with a slave computer; a spatial movement system realizing control of any spatial position through circumferential movement, radial movement and vertical movement; a real-time three-dimensional display system built into the host computer system; an audio system randomly generates a type of audio data of a sound source and a sound source with equal-difference decibels; and a test system for matching human spatial positioning results to sound source spatial data and providing an objective evaluation. The invention further provides a method of providing a parametric minimum audible angle for a capability of auditory spatial positioning, the invention improves the control accuracy.

Abstract: Aspects are directed to a reference electrode integrated on a surface of a substrate to facilitate functionalization of a working electrode. The reference electrode is used in the electrochemical deposition or electrodeposition of one or more functional layers on a working electrode. The working electrode may be a sensing element of an analyte-selective sensor. Additional aspects of the current subject matter are directed to a counter electrode integrated on a surface of a substrate.

Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.

Abstract: There is provided a wearable device for quantitatively detecting a biomarker in a sweat sample obtained from the skin of a subject. The wearable device comprises a microfluidic network. The microfluidic network comprises a reservoir filled with a carrier fluid containing a predetermined amount of a marker; a sample collection chamber disposed downstream from the reservoir and adapted to contact the skin of the subject and collect a sweat sample; a first sensor disposed downstream from the sample collection chamber and adapted to detect the marker; and a second sensor disposed downstream from the first sensor and adapted to detect the biomarker.

Abstract: The present disclosure relates to a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device is produced in a state in which a body attachment unit has been assembled inside an applicator, so as to minimize a user's additional work of attaching the body attachment unit to the body, thereby enabling the body attachment unit to be attached to the body only by simply activating the applicator.

Abstract: Low profile continuous analyte measurement systems and systems and methods for implantation within the skin of a patient are provided.

Abstract: The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.

Abstract: A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.

Abstract: A virtual Hebb-Williams maze task, comprising at least four of Hebb-Williams mazes selected from the group consisting of mazes 5, 6, 8, 11, and 12; a computer implemented software capable of detecting pointer position according to a coordinate system for tracking the position and time of the user; and wherein the position and time of the user can be annotated to define a score which can be compared to a control; and wherein a score of more than one standard deviation below the control identifies a child at risk for Reading Disorder.

Abstract: A stress evaluation and calibration method and apparatus, and a storage medium are disclosed. The stress evaluation and calibration method includes: obtaining a physiological parameter signal of a user; determining a smallest stress state value of the user within preset duration based on an eigenvalue vector of the physiological parameter signal and a stress evaluation system; determining calibration information based on a smallest reference stress value of a group to which the user belongs and the smallest stress state value; and calibrating, by using the calibration information, a stress state value output by the stress evaluation system, to determine a theoretical stress state value of the user. With the stress evaluation and calibration method and apparatus, a stress evaluation result can be automatically calibrated, to improve evaluation accuracy, and active participation of the user is not required, to improve user experience.

Abstract: The present application is applicable to the field of computer application technology, and provides methods and devices for detecting driver distraction, including: acquiring the EEG data of the driver; preprocessing the EEG data, and then inputting it into a pre-trained distraction detection model to obtain the distraction detection result of the driver; obtaining the distracted detection model by training a preset convolution-recurrent neural network using EEG sample data and corresponding distracted result label; sending the distraction detection result to an in-vehicle terminal associated with the identity information of the driver, wherein the distraction detection result is used to trigger the in-vehicle terminal to generate driving reminder information according to the distraction detection result. When detecting driver distraction, the accuracy and efficiency are improved, thereby reducing the probability of traffic accidents.

Abstract: A biological information measurement device which is capable of improving accuracy of detection of optimal exercise intensity, a biological information measurement method, and a biological information measurement program are provided. At the biological information measurement device, heart rate counting means measures an HR value indicating a heart rate on the basis of heart-rate data obtained by capturing heartbeats when a subject to be measured exercises, and analysis means performs power spectrum analysis on a heart rate variability frequency of the heart-rate data to calculate an LF value which is an integral value of low frequency components. Detection means then detects an HR/LF value by dividing the HR value with respect to exercise intensity of the subject to be measured by an LF value. Thus, by the biological information measurement device obtaining the HR/LF value as a new index indicating sympathetic nerve activity, it is possible to obtain biological information important for health management.

Abstract: According to one embodiment, a magnetic sensor includes a first magnetic element, a second magnetic element, a third magnetic element located between the first and second magnetic elements in a first direction, a fourth magnetic element located between the third and second magnetic elements in the first direction, a first conductive member, a second conductive member, a third conductive member located between the first and second conductive members in the first direction, a fourth conductive member located between the third and second conductive members in the first direction, a first magnetic member, a second magnetic member, a third magnetic member located between the first and second magnetic members in the first direction, a fourth magnetic member located between the third and second magnetic members in the first direction, and a fifth magnetic member located between the third and fourth magnetic members in the first direction.

Abstract: A measurement system is proposed for building a magnetic field map of an object. The system comprising: a light source arrangement for emitting a plurality of light beams, a respective light beam being configured to travel in the measurement system along a respective optical path; a plurality of measurement sensors sharing a first magneto-optical layer comprising at least a first Faraday material layer and a first light reflector for reflecting the plurality of light beams travelled through the first Faraday material layer in a first direction back to the first Faraday material layer in a second, opposite direction; one or more reference sensors; and one or more light detectors.

Abstract: A smart clothes for sensing heart physiological activities and lung respiratory conditions is provided, the smart clothes utilizes conductive connecting elements for being externally connected to a control module, such that the control module can be expanded or upgraded according to functional requirements. Further in the smart clothes, sensing elements and signal transmission wires are made of conductive fabric. As the conductive fabric sensing elements and signal transmission wires are well attached to a clothing body of the smart clothing, the sensing elements can be better adhered to human skin, and thereby sensing accuracy is improved.

Abstract: A wearable diagnostic electrocardiogram (ECG) garment is disclosed herein. The wearable diagnostic ECG garment comprises a garment body, screen-printed electrodes positioned on the body, and screen-printed wires positioned in the garment body, each of the screen-printed wires connected from a central connector module to a screen-printed electrode.

Abstract: A patch type electrocardiogram (ECG) sensor including base layer having pad form; flexible printed circuit board (FPCB) layer formed on the base layer and having film form; sensor formed on FPCB layer and including plurality of electrodes configured to acquire ECG signals and plurality of electrode circuit parts which are constituted by circuit patterns and the first ends thereof are individually connected to the plurality of electrodes; main body formed on the FPCB layer and connected to second ends of the plurality of electrode circuit parts to converge the plurality of electrode circuit parts; and adhesive layer formed on FPCB layer such that plurality of electrodes are exposed and configured to attach the sensor to human body, connection part configured to transmit the ECG signals to the outside is installed at and connected to the main body, and main body and the connection part are connected by wire.

Abstract: Catheters, systems, and related methods for optimized for mapping, minimizing, and treating cardiac fibrillation in a patient, including an array of at least one stacked electrode pair, each electrode pair including a first electrode and a second electrode, wherein each electrode pair is configured to be orthogonal to a surface of a cardiac tissue substrate, wherein each first electrode is in contact with the surface to record a first signal, and wherein each second electrode is separated from the first electrode by a distance which enables the second electrode to record a second signal, wherein the catheter is configured to obtain one or more measurements from at least a first signal and a second signal in response to electrical activity in the cardiac tissue substrate indicative of a number of electrical circuit cores and distribution of the electrical circuit cores for a duration across the cardiac tissue substrate.

Abstract: A method is provided. The method is implemented by a mapping engine stored as program code on a memory and executed by a processor. The method include subdividing an anatomical mesh of a part of an anatomical structure to one or more other meshes of the anatomical structure. The one or more other meshes are more granular than the anatomical mesh. The method includes interpolating local activation time values and velocity values for the one or more other meshes and tracing a path of velocity vectors on the one or more other meshes in accordance with the interpolation of the local activation time values and velocity values. The method also includes projecting the path on the anatomical mesh to provide an enhanced visualization of the anatomical structure.

Abstract: A computer-implemented method may comprise providing a wireless tri-axial seismocardiography (SCG) device configured to measure and time-stamp movements of a user's chest caused by the user's heart beats; positioning the SCG device on the user's chest in a predetermined orientation and initiating a test; using the positioned SCG device, detecting, sampling, digitizing and time-stamping movement vectors of the user's chest over a predetermined period of time in each of x, y and z directions; storing the time-stamped digitized movement vectors in a memory of the SCG device and sending the time-stamped digitized movement vectors to at least one of the app on the mobile device and the remote server over a computer network; receiving, by the app on the mobile device, a plurality of fiduciary markers from the remote server, the plurality of fiduciary markers being detected from or derived using the time-stamped digitized movement vectors in each of x, y and z directions; and generating a report on the mobile device

Abstract: A computer-implemented method may comprise providing a wireless tri-axial seismocardiography (SCG) device configured to measure and time-stamp movements of a user's chest caused by the user's heart beats; positioning the SCG device on the user's chest in a predetermined orientation and initiating a test; using the positioned SCG device, detecting, sampling, digitizing and time-stamping movement vectors of the user's chest over a predetermined period of time in each of x, y and z directions; storing the time-stamped digitized movement vectors in a memory of the SCG device and sending the time-stamped digitized movement vectors to at least one of the app on the mobile device and the remote server over a computer network; receiving, by the app on the mobile device, a plurality of fiduciary markers from the remote server, the plurality of fiduciary markers being detected from or derived using the time-stamped digitized movement vectors in each of x, y and z directions; and generating a report on the mobile device

Abstract: An auscultatory sound signal from at least one auscultatory sound-or-vibration sensor is filtered with a high-pass filter and then segmented into a plurality of associated heart cycle segments responsive to associated R-peak locations of an electrographic envelope signal representing an envelope response to an even power of an associated electrographic signal from an ECG sensor. A representation an envelope responsive to an even power of said auscultatory sound signal within said at least one heart cycle is locally modeled about at least a second peak to provide for locating the start of diastole of said at least one heart cycle.

Abstract: A system is described for predicting at least one cardiological dysfunction in an individual, having a means for providing an ECG which has a number n of time-synchronized ECG traces, each comprising a chronological sequence of time signals representing a sinus rhythm of the individual's heartbeat, to which at least one P wave, a QRS complex and a T wave can be assigned in chronological order.

Abstract: A method includes estimating, by a consumer electronic device, an atrial fibrillation (AF) burden of a subject based on multiple measurements passively collected by at least one sensor associated with the consumer electronic device while the subject is in a free-living environment. The method also includes outputting, by the consumer electronic device, an AF burden notification associated with the subject based on the estimated AF burden. The method further includes outputting, by the consumer electronic device, an AF burden recommendation based on the estimated AF burden.

Abstract: The object of the invention is a method for determining electrical activity of cardiac muscle, characterised in that the resultant electric potential (Vwyp) forming the QRS complex in the electrocardiogram obtained during the ECG test is decomposed into partial potentials corresponding to the depolarization of specific areas (i) of the left ventricular muscle (MS).

Abstract: A method is provided. The method is implemented by an interpretation engine executed by processors coupled to a memory. The method includes receiving a bipolar intracardiac reference signal from reference electrodes of a catheter and executing a preprocessing of the bipolar intracardiac reference signal. The method further includes interpreting the bipolar intracardiac reference signal according to a threshold for contact by a reference electrode of the electrodes.

Abstract: Systems and methods for the evaluation of clinical treatment efficacy is disclosed. The systems and methods include protocols for selection of appropriate patients/subjects for the evaluation of a specific clinical treatment. The systems and methods are based on objective measures of brain activity. The clinical treatments include pharmacological compounds in development or existing compounds approved by the appropriate regulatory authority (e.g., U.S. Federal Drug Administration), as well as transcranial magnetic or electric stimulation, including non-invasive approaches as well as grid- or depth-based electrode arrays, as well as behavioral therapies.

Abstract: A typing data analysis system may be used to accurately detect early onset of CNS diseases and psychiatric disorders based on typing data. The typing data analysis system may use distance based data analytics techniques to diagnose CNS diseases and psychiatric disorders with high accuracy. The distance based data analytics techniques may include a distance analysis that determines the distance between two or more sets of inconsistency measures that are associated with a particular individual, disease, or disorder. The distance between inconsistency measures for two or more diseases/disorders may be used to better differentiate between each disease/disorder. The distance between the inconsistency measures for an individual and a disease/disorder may help more accurately screen the individual for the disease/disorder.