Patents Issued in April 13, 2023
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Publication number: 20230109822Abstract: An aircraft includes an airfoil and a hinge member to rotatably couple the airfoil to a structure of an aircraft. The hinge member defines at least a portion of a rotational axis. The aircraft also includes an indexing mechanism coupled to the airfoil and configured to, in a first state, inhibit rotation of the airfoil about the rotational axis, and in a second state, to permit rotation of the airfoil about the rotational axis between a first position and a second position that is angularly indexed relative to the first position. The aircraft further includes an actuator to selectively change a state of the indexing mechanism from the first state to the second state, from the second state to the first state, or both.Type: ApplicationFiled: October 11, 2021Publication date: April 13, 2023Inventor: John Emil Johnson
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Publication number: 20230109823Abstract: A multi-phase boost converting apparatus includes a multi-phase boost converter and a passive lossless snubber, wherein the passive lossless snubber includes a first resonant capacitor, a second resonant capacitor, an output-end first unidirectional conduction component, an output-end second unidirectional conduction component, an input-end first unidirectional conduction component, an input-end second unidirectional conduction component and a resonant inductor.Type: ApplicationFiled: January 11, 2022Publication date: April 13, 2023Inventor: Tsung-Liang HUNG
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Publication number: 20230109824Abstract: A triboelectric generator is disclosed. The triboelectric generator according to an embodiment of the present disclosure includes a flexible electrode part comprising a first and a second dielectric layer, and at least one metal layer; and a fixed electrode part spaced apart from both sides of the flexible electrode part, and comprising a first and a second electrode connected to each other, wherein the flexible electrode part generates triboelectrification based on contact and non-contact by a fluid flow, and an electric charge moves through the metal layer, thereby effectively moving electric charges generated by triboelectrification, and increasing the friction frequency to enhance power generation efficiency.Type: ApplicationFiled: March 5, 2020Publication date: April 13, 2023Applicants: LG ELECTRONICS INC., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Byungsoo OH, Yoseop SHIN, Sungjun CHO, Gunyoung JUNG
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Publication number: 20230109825Abstract: A method and a device for encoding or decoding based on an inter-frame prediction. The method includes steps of: determining a temporal motion vector prediction value of a to-be-processed coding unit, where the temporal motion vector prediction value is a temporal motion vector prediction value of a sub-block, a temporal motion vector of which is obtainable through prediction, in sub-blocks adjacent to the to-be-processed coding unit and/or sub-blocks in the to-be-processed coding unit; determining a motion vector residual prediction value of the to-be-processed coding unit according to the temporal motion vector prediction value; determining a motion vector of a sub-block in the to-be-processed coding unit according to the temporal motion vector prediction value and the motion vector residual prediction value and performing a motion compensation according to the motion vector of the sub-block in the to-be-processed coding unit to determine a prediction block of the to-be-processed coding unit.Type: ApplicationFiled: October 25, 2019Publication date: April 13, 2023Inventors: Ronggang WANG, Xi XIE, Kui FAN, Wen GAO
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Publication number: 20230109826Abstract: An electrical current generating device having a sound wave force magnifying structure in the form of a force transmission pin which is longitudinally slidable within a body bore and having a proximal end of a large area for receiving sound wave forces, and having a greatly reduced area distal end which bears on a piezoelectric element.Type: ApplicationFiled: September 12, 2022Publication date: April 13, 2023Inventor: John M. Leslie
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Publication number: 20230109827Abstract: Apparatuses, methods, and systems are disclosed for supporting irregular subcarrier spacing. One apparatus (900) includes a transceiver (925) and a processor (905) that receives (1105) an indication of at least one value of irregular subcarrier spacing. The processor (905) controls the transceiver (925) to communicate (1110) with a Radio Access Network (“RAN”) by applying the indicated irregular subcarrier spacing to resource elements (“REs”) in multiple physical resource block groups (“PRGs”).Type: ApplicationFiled: March 25, 2021Publication date: April 13, 2023Inventors: Ankit Bhamri, Ali Ramadan Ali, Karthikeyan Ganesan, Alexander Johann Maria Golitschek Edler von Elbwart, Vijay Nangia
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Publication number: 20230109828Abstract: Image encoding/decoding methods and apparatuses according to the present invention may generate a prediction block of a current block based on a pre-defined prediction mode, generate a transform block of the current block through predetermined transformation, and reconstruct the current block based on the prediction block and the transform block.Type: ApplicationFiled: October 31, 2022Publication date: April 13, 2023Inventors: Bae Keun LEE, Dong San JUN
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Publication number: 20230109829Abstract: In some embodiments, the present disclosure relates to method for forming an image sensor integrated chip. The method includes forming a first photodetector region in a substrate and forming a second photodetector region in the substrate. A floating diffusion node is formed in the substrate between the first photodetector region and the second photodetector region. A pick-up well contact region is formed in the substrate. A first line intersects the floating diffusion node and the pick-up well contact region. One or more transistor gates are formed on the substrate. A second line that is perpendicular to the first line intersects the pick-up well contact region and the one or more transistor gates.Type: ApplicationFiled: December 9, 2022Publication date: April 13, 2023Inventors: Seiji Takahashi, Chen-Jong Wang, Dun-Nian Yaung, Feng-Chi Hung, Feng-Jia Shiu, Jen-Cheng Liu, Jhy-Jyi Sze, Chun-Wei Chang, Wei-Cheng Hsu, Wei Chuang Wu, Yimin Huang
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Publication number: 20230109830Abstract: A UE receives downlink control information from a network and schedules a plurality of component carriers using the downlink control information. The UE applies information of a bandwidth part indicated by the downlink control information to the plurality of component carriers.Type: ApplicationFiled: March 23, 2020Publication date: April 13, 2023Applicant: NTT DOCOMO, INC.Inventors: Hiroki Harada, Shohei Yoshioka, Shinya Kumagai, Yuki Matsumura, Yuki Takahashi, Satoshi Nagata
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Publication number: 20230109831Abstract: A data storage device includes a hard disk drive coupled to a printed circuit board (PCB), a volatile memory device coupled to the PCB, a non-volatile memory device coupled to the PCB, and a controller coupled to the PCB, such that the controller is in communication with the hard disk drive, the volatile memory device, and the non-volatile memory device. The controller is configured to identify patterns and/or structures of metadata for the hard disk drive, perform one or more of the following to the metadata to tailor the metadata: data shaping, content aware decoding, adaptive data trimming, and/or adaptive metablock sizing, and write the tailored metadata to the non-volatile memory device. The metadata is at least one of repeatable run out metadata, positioning error signal metadata, adjacent track interference metadata, and/or emergency power off metadata.Type: ApplicationFiled: September 30, 2021Publication date: April 13, 2023Inventors: Gilat FLAISHMAN, Stella ACHTENBERG, Omer FAINZILBER, Eran SHARON, David Robison HALL
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Publication number: 20230109832Abstract: Multi-layer films for making bags for containing flowable materials, in particular to large bags for dairy products. The multi-layer films have an outer and an inner sealant layer and a core layer and optionally, an interposed layer positioned between the outer sealant layer and the core layer and between the core layer and the inner sealant layer. The outer and inner sealant layers contain an ethylene/a-olefin interpolymer composition and the intermediate layer optionally contains this interpolymer composition.Type: ApplicationFiled: December 15, 2022Publication date: April 13, 2023Inventor: Nicholas Farkas
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Publication number: 20230109833Abstract: The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of bacterial infections in humans and other mammals. A new class of small molecules is disclosed that inhibits the bacterial trans-translation/ribosome rescue mechanism and thus blocks infection of host cells by bacteria. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of bacterial infections.Type: ApplicationFiled: October 13, 2022Publication date: April 13, 2023Applicants: MICROBIOTIX, INC., THE PENN STATE RESEARCH FOUNDATIONInventors: Zachary D. Aron, Steven M. Kwasny, Matthew C. Torhan, Jay P. Barbor, Steven C. Cardinale, Michelle M. Butler, Timothy J. Opperman, Kenneth C. Keiler
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Publication number: 20230109834Abstract: A gas regulator includes a valve chamber body that houses two valves of the regulator. Valve elements that move to open and close the two valves are received via a same opening into the valve chamber body, which is closed by a plug. The plug can define a first valve seat as well as a piercing element used to pierce a compressed gas cylinder. A retainer can hold a gasket at a valve seat as well as provide a bore or other support for a valve element and valve element spring.Type: ApplicationFiled: October 4, 2022Publication date: April 13, 2023Applicant: Coravin, Inc.Inventor: Lauren Michelle Inch
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Publication number: 20230109835Abstract: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.Type: ApplicationFiled: December 13, 2022Publication date: April 13, 2023Applicant: Antares Pharma, Inc.Inventors: Thomas E. Kramer, Peter L. Sadowski
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Publication number: 20230109836Abstract: The present invention relates to a distributed energy source system utilizing waste heat deeply. The distributed energy source system utilizing waste heat deeply comprises a primary waste heat recycling module, a membrane distillation type seawater desalination module and a membrane type thermoosmosis power generation module. The distributed energy source system utilizing waste heat deeply provided by the present invention can recycle and deeply utilize waste heat and moisture in flue gas by means of the primary waste heat recycling module, the membrane distillation type seawater desalination module and the membrane type thermoosmosis power generation module to realize functions of seawater desalination and low-temperature power generation, has high energy utilization ratio and improves the waste heat utilization efficiency.Type: ApplicationFiled: March 3, 2022Publication date: April 13, 2023Applicant: Dongguan University of TechnologyInventors: Simin HUANG, Minlin YANG, Kui HE, Wuzhi YUAN
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Publication number: 20230109837Abstract: A method for verifying aperture positions of a pre-patient collimator of a computed tomography (CT) imaging system includes obtaining data collected by an X-ray measurement device having detector elements subjected to X-rays emitted from an X-ray source of the CT imaging system with the pre-patient collimator at an expected aperture position. The method also includes calculating a measured collimator aperture position for the pre-patient collimator based on the obtained data. The method further includes comparing the measured collimator aperture position to a system specification for the expected aperture position for the CT imaging system. The method even further includes generating an output based on the comparison of the measured collimator aperture position to the system specification.Type: ApplicationFiled: October 4, 2021Publication date: April 13, 2023Inventors: Arka Datta, John Moore Boudry, Brandon Allan Smith
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Publication number: 20230109838Abstract: A side tipper system for a vehicle includes a container for carrying material and selectively discharging carried material. The container includes a container body defining an upper portion of a first side wall, a second side wall opposing the first side wall, and a pair of opposing end walls; a floor pivotally coupled to the second side wall; and a side door pivotally coupled to the floor and defining a lower portion of the first side wall in a closed position and forming a discharge opening in an open position. The system further includes end assemblies configured to be mounted to a vehicle chassis at respective ends of the container, each end assembly operatively coupled to the container for supporting the container and for controlling discharge of material by: moving the side door from the closed position to the open position; and lifting the container body relative to the chassis.Type: ApplicationFiled: March 5, 2021Publication date: April 13, 2023Applicant: AS INNOVATIVE HOLDINGS PTY LTDInventor: Kieran CHIVERTON
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Publication number: 20230109839Abstract: The present invention is to provide a medicament for treating and/or preventing tauopathy by activating the voltage-gated sodium channel (Nav). The present invention relates to a medicament for treating and/or preventing tauopathy, comprising a Nav activator as an active ingredient.Type: ApplicationFiled: January 6, 2021Publication date: April 13, 2023Applicant: SUMITOMO PHARMA CO., LTD.Inventors: Kazuaki SAMPEI, Takeo ISHIYAMA, Atsushi IKEDA, Taizo ISHIKAWA, Makoto HIGUCHI, Hiroyuki TAKUWA, Yuhei TAKADO
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Publication number: 20230109840Abstract: A system and method for mobile device multitenant active and ambient callback prioritization, utilizing a callback integration engine to generate callback lists for multiple tenants, an environment analyzer, and a prioritization engine operating on a user's mobile device for integration through the operating system and software applications operating on the device, wherein the environment analyzer retrieves and aggregates ambient data related to the mobile device, inputs the aggregated ambient data into one or more machine learning algorithms wherein the algorithms may analyze the input data, the results of the analysis may be used to compute whether a user is available to be prioritized to receive a callback.Type: ApplicationFiled: October 25, 2022Publication date: April 13, 2023Inventors: Matthew DiMaria, Shannon Lekas, Daniel Bohannon
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Publication number: 20230109841Abstract: An antenna alignment apparatus may include magnetic field sensors as an alternative to or in addition to GNSS sensors. The magnetic field sensors may measure the earth's magnetic fields at corresponding locations, and a processor may use the measurements to calculate at least one of a roll, tilt, or azimuth of an antenna. For an optical alignment, the antenna alignment apparatus may, additionally or alternately, include a reference object (e.g., a printed mark or a physical stud) located within a field of view of a camera. A location of the reference object may indicate the alignment of the antenna vis-a-vis the structures within the field of view.Type: ApplicationFiled: October 13, 2021Publication date: April 13, 2023Applicant: Viavi Solutions Inc.Inventors: Raleigh Benton STELLE, IV, Thomas SEVILLA
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Publication number: 20230109842Abstract: An autonomous driving system includes an electronic control unit. The electronic control unit is configured to suggest to a driver that a host vehicle overtake a preceding vehicle during autonomous driving, recognize whether the driver accepts a suggestion for the overtaking, when the electronic control unit recognizes that the driver accepts the suggestion, cause the host vehicle to overtake the preceding vehicle, and, when the electronic control unit recognizes that the driver rejects the suggestion, not cause the host vehicle to overtake the preceding vehicle, set a first prohibition duration, and, when the electronic control unit suggests to the driver that the host vehicle overtake the preceding vehicle and recognizes that the driver rejects the suggestion, extend the first prohibition duration as compared to when the electronic control unit suggests to the driver that the host vehicle overtake the preceding vehicle and recognizes that the driver accepts the suggestion.Type: ApplicationFiled: December 14, 2022Publication date: April 13, 2023Applicant: TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Naoki Nishimura, Shingo Shibata
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Publication number: 20230109843Abstract: The present invention provides a photosensitive resin composition and a cured film prepared therefrom. The photosensitive resin composition includes a mixture of two or more siloxane polymers having different dissolution rates with respect to an aqueous solution of tetramethylammonium hydroxide. The composition keeps high transparency and high sensitivity, which are advantages of a composition containing a siloxane polymer, and has excellent chemical resistance, thereby providing a cured film having excellent stability in a post-processing.Type: ApplicationFiled: December 14, 2022Publication date: April 13, 2023Inventors: Jong Han YANG, Geun HUH, Jin KWON, Jong-Ho NA
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Publication number: 20230109844Abstract: A painting device equipped with a painting head having multiple nozzles that discharge coating material toward an object of painting. The painting device includes a supply passage that supplies the coating material to the painting head, and a return flow passage that returns, to the upstream side of the supply passage. A portion of the coating material supplied to the painting head that was not discharged from the multiple nozzles is possessed by the painting head, wherein the supply passage, the painting head, and the return flow passage constitute a coating material circulation passage. The coating material circulation passage is divided into multiple segments, each of which contains at least one of the multiple circuit component parts arranged in the coating material circulation passage or the painting head, and wherein the coating material circulation passage allows the multiple segments to be cleaned individually.Type: ApplicationFiled: September 30, 2022Publication date: April 13, 2023Inventor: Kuniharu Yamauchi
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Publication number: 20230109845Abstract: An electrical connection device includes a first jaw and a second jaw facing the first jaw in a closed state. The first jaw has a first insertion surface perpendicular to an insertion direction into a connection casing, a first surface facing the second jaw that is substantially parallel to the insertion direction, and an opposite first surface opposite the first insertion surface. The first jaw has a first recess. The second jaw has a second surface facing the first jaw and extending substantially parallel to the insertion direction, a second insertion surface introduced over the connection casing and perpendicular to the insertion direction, and an opposite second surface opposite to the second insertion surface. The second jaw has a second recess facing the first recess in the closed state. The first recess and/or the second recess has a rod at the first edge and/or the second edge.Type: ApplicationFiled: October 7, 2022Publication date: April 13, 2023Applicant: Tyco Electronics France SASInventors: Veronique Brenca, Imad Smirani, Xavier Rouillard
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Publication number: 20230109846Abstract: Techniques described herein may be utilized to serialise and de-serialise arithmetic circuits that are utilized in the execution of computer programs. The arithmetic circuit may be utilized to build a Quadratic Arithmetic Problem (QAP) that is compiled into a set of cryptographic routines for a client and a prover. The client and prover may utilize a protocol to delegate execution of a program to the prover in a manner that allows the client to efficiently verify the prover correctly executed the program. The arithmetic circuit may comprise a set of symbols (e.g., arithmetic gates and values) that is compressed to produce a serialised circuit comprising a set of codes, wherein the set of symbols is derivable from the set of codes in a lossless manner. Serialisation and de-serialisation techniques may be utilized by nodes of a blockchain network.Type: ApplicationFiled: August 13, 2022Publication date: April 13, 2023Inventors: Alexandra COVACI, Patrick MOTYLINSKI, Simone MADEO, Stephane VINCENT, Craig Steven WRIGHT
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Publication number: 20230109847Abstract: Disclosed are methods, systems, and non-transitory computer-readable media for providing contextual building height information to one or more operators of an aircraft. For instance, the method may include obtaining aircraft flight information including a current position and a current altitude of the aircraft; and retrieving, from a database, building information for one or more buildings located in a flight path area, the flight path area including the current position of the aircraft. The method may further include assigning one or more visual characteristics to each of the one or more buildings located in the flight path area based at least in part on the building information and the current altitude of the aircraft; and displaying, to the one or more operators of the aircraft, the one or more buildings located in the flight path area with the assigned one or more visual characteristics.Type: ApplicationFiled: December 7, 2021Publication date: April 13, 2023Inventors: Saravanakumar GURUSAMY, Madhava Gadicherla, Jayasenthilnathan Balasubramanian
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Publication number: 20230109848Abstract: In general, devices, systems, and methods for fiducial identification and tracking are provided.Type: ApplicationFiled: October 5, 2021Publication date: April 13, 2023Inventors: Frederick E. Shelton, IV, Jason L. Harris, Daniel J. Mumaw, Charles J. Scheib
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Publication number: 20230109849Abstract: An electronic apparatus performs a method of coding video data. The method comprises: receiving, from the bitstream, syntax elements associated with a coding unit, wherein the syntax elements include a first coded block flag (CBF) for residual samples of a first chroma component, a second CBF for residual samples of a second chroma component, and a third syntax element indicating whether adaptive color transform (ACT) is applied to the coding unit; determining whether to perform the chroma residual scaling to the residual samples of the chroma components according to the first CBF, the second CBF, and the third syntax element; in accordance with a determination to perform the chroma residual scaling to the residual samples of the first and second chroma components, scaling the residual samples of the at least one of the first and second chroma components based on a corresponding scaling parameter.Type: ApplicationFiled: December 12, 2022Publication date: April 13, 2023Inventors: Xiaoyu XIU, Yi-Wen CHEN, Tsung-Chuan MA, Hong-Jheng JHU, Wei CHEN, Che-Wei KUO, Xianglin WANG, Bing YU
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Publication number: 20230109850Abstract: A system enables a consumer to place an order for a food item by entering characteristics and not necessary by its commercial name. The system prompts the consumer to enter the information about the desired food item and selects food items from a food database according to the characteristics entered. The selected food items are presented to the consumer for confirmation and the confirmed food item is sent to a selected restaurant for fulfillment.Type: ApplicationFiled: March 1, 2022Publication date: April 13, 2023Inventor: Quyen T. Kiet
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Publication number: 20230109851Abstract: A cable television (CATV) entry adapter connects to a CATV network and serves as a hub in an In-Home Entertainment (IHE) network. IHE signals may be communicated between passive and active ports of an embodiment of the entry adapter through a pair of directional couplers which allow an IRE-enabled embedded multimedia terminal device (eMTA) at the passive port to communicate with multimedia devices of the IHE network connected to the active ports. An IHE frequency rejection filter is used in some embodiments to confine IHE signal to a single subscriber premise. In some embodiments a bidirectional IHE bandpass filter is used to enable IHE signals to pass between the passive and active ports of the CATV entry adapter.Type: ApplicationFiled: December 13, 2022Publication date: April 13, 2023Applicant: PPC BROADBAND, INC.Inventors: Chad T. Wells, John M. Egan, Jr., Gregory F. Halik, Charles F. Newby
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Publication number: 20230109852Abstract: A data processing method includes: in response to a service enabling operation in a video application, enabling a video recording service in the video application; collecting, using the video recording service, user voice data; determining and identifying a target text that matches prompting text data associated with the video recording service; and acquiring target video data corresponding to the video recording service until a text position of the target text in the prompting text data is at an end of the prompting text data. Embodiments of this application improve the effectiveness of teleprompting functions during a video recording, and the quality of a recorded video may further be improved.Type: ApplicationFiled: November 17, 2022Publication date: April 13, 2023Inventors: Guangwen YU, Huafeng FAN, Tao YANG
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Publication number: 20230109853Abstract: The present invention relates to a scanning electron microscope configured to scan a workpiece, such as a wafer, mask, panel, or substrate, with an electron beam to generate an image of the workpiece. The scanning electron microscope includes a deflector (17, 18) configured to deflect the electron beam to scan a target region (T) on the workpiece (W) with the electron beam, and a deflection controller (22) configured to apply to the deflectors (17, 18) a scanning voltage that causes the electron beam to scan the target region (T) and an offset voltage that shifts the electron beam from an optical axial center (O) to the target region (T).Type: ApplicationFiled: March 18, 2021Publication date: April 13, 2023Inventors: Naoya SAITOH, Daisuke KUBOTA
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Publication number: 20230109854Abstract: A method includes using a machine-learning model to determine multiple sets of image data, each representing an estimated solution to an inverse problem associated with multiple waveform return measurements. First image data are based on a first set of waveform return measurements and first model parameters of the machine-learning model, and second image data are based on a second set of waveform return measurements and a second model parameters of the machine-learning model. The method also includes determining, based on the multiple sets of image data, a representative image. The method further includes generating output data that identifies a first area of the representative image as less reliable than a second area of the representative image based on a statistical evaluation of two or more sets of image data of the multiple sets of image data.Type: ApplicationFiled: October 12, 2022Publication date: April 13, 2023Inventors: Alexandru Ardel, Elad Liebman, Mrinal Sen, Georgios Alexandros Dimakis, Yash Gandhi, Sriram Ravula, Dimitri Voytan
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Publication number: 20230109855Abstract: A disclosure of the present specification provides a method for performing direct communication by a first UE. The method may comprise the steps of: transmitting, to a second UE, a request message for establishing a unicast link; and receiving, from the second UE, a response message regarding the request message.Type: ApplicationFiled: March 4, 2021Publication date: April 13, 2023Inventor: Sungduck CHUN
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Publication number: 20230109856Abstract: A system includes a display and a processor. The processor is configured to compute multiple forecasted local activation times (LATs) at different respective locations on cardiac tissue of a subject, by simulating a propagation of a physiological activation potential along the cardiac tissue with a particular portion of the cardiac tissue, which is currently conductive, being non-conductive. The processor is further configured to generate, based on the forecasted LATs, a forecasted electroanatomical map representing a forecasted state of the cardiac tissue following an ablation of the particular portion of the cardiac tissue, and to display the forecasted electroanatomical map on the display. Other embodiments are also described.Type: ApplicationFiled: October 11, 2021Publication date: April 13, 2023Inventors: Elias Shamilov, Vladimir Rubinstein, Avram Dan Montag, Konstantin Feldman, Alexander Gorovoy
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Publication number: 20230109857Abstract: The present disclosure pertains to a method for diagnosing a middle ear disease comprising receiving one or more otoscopic image of a subject, pre-processing the one or more otoscopic image to obtain image data, inputting the image data to a trained network model, generating, using the trained network model, an output that characterizes the health of the subject with respect to the middle ear disease, and generating a diagnostic result based on the output, wherein the trained network model is based on a model selected from the group consisting of a MobileNetV2 model, a NASNetMobile model, and a DenseNet201 model.Type: ApplicationFiled: September 21, 2022Publication date: April 13, 2023Applicant: Taipei Veterans General HospitalInventors: Yuan-Chia Chu, Yen-Fu Cheng, Wen-Huei Liao, Yen-Chi Chen
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Publication number: 20230109858Abstract: The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.Type: ApplicationFiled: July 29, 2022Publication date: April 13, 2023Inventors: Philip JONES, Barbara CZAKO, Jason CROSS, Paul LEONARD, Faika MSEEH, Connor PARKER
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Publication number: 20230109859Abstract: Synthetic training interface devices, methods, and systems. A synthetic training device includes a processor, a communications interface in communication with the processor, a measurement device in communication with the processor, and an input device disposed on a live training device and configured to receive input from a user. Calibration information is captured. The calibration information includes orientation, position, inertial, and/or geometric information regarding the synthetic training interface device, a live training device coupled to the synthetic training interface device, the user, and/or a synthetic training environment. The calibration information is captured via a measurement device and/or user input.Type: ApplicationFiled: November 23, 2022Publication date: April 13, 2023Applicant: Booz Allen Hamilton Inc.Inventors: RITCH CHAD, Lynwood Rabon, Jon Purgason, James B. Hartman
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Publication number: 20230109860Abstract: The present invention relates to an access arrangement (90) of a wind turbine blade for accessing a hollow space within the blade. The access arrangement (90) comprises an access opening (180) provided in the blade shell member, a cover panel (92) for covering the access opening (180), a sealing member (96) arranged between the cover panel (92) and the blade shell member, and one or more fasteners (98) for releasably fastening the cover panel (92) to the blade shell member. The present invention also relates to a wind turbine blade comprising the access arrangement (90).Type: ApplicationFiled: December 14, 2022Publication date: April 13, 2023Applicant: BLADE DYNAMICS LIMITEDInventors: Andrea AVALDI, Chris Paul SWATTON, Harry George James FISH, Jelmer CNOSSEN, Manish MUKHERJEE
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Publication number: 20230109861Abstract: A method of counting the number of puffs using an aerosol generating device is disclosed. The may include obtaining a first start time which is a time when a pressure measured by a sensor included in the aerosol generating device decreases below a first reference pressure value; obtaining a first end time which is a time when the pressure measured by the sensor reaches the first reference pressure value after the first start time; determining whether a first period, which is a period between the first end time and the first start time, is longer than or equal to a first reference period; and increase the number of puffs by one based on the first period being longer than or equal to the first reference period.Type: ApplicationFiled: April 14, 2020Publication date: April 13, 2023Applicant: KT&G CORPORATIONInventors: Byung Sung CHO, Won Kyeong LEE, Jong Sub LEE, Dae Nam HAN
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Publication number: 20230109862Abstract: A mixing system (10) including a base module (12), a mixing unit (26), and an enclosure (14). The base module (12) includes a base support (16), a drive unit (18) disposed within the base support (16), a drive shaft (22) coupled to the drive unit (18), and a drive head (24) coupled to the drive unit (18) via the drive shaft (22) and disposed within the base support (16). The drive head (24) includes a first magnet (25). The mixing unit (26) includes a guide element (28) and an agitator (30) slidably coupled to the guide element (28). The agitator (30) includes a second magnet (32) and at least one vane (34). The enclosure (14) is coupled to the base support (16) encloses the guide element (28) and the agitator (30). The drive unit (18) and the drive head (24) are configured to generate a linear pulsating movement of the agitator (30) along the guide element (28) for mixing a fluid medium (47) within the enclosure (14).Type: ApplicationFiled: April 1, 2021Publication date: April 13, 2023Inventors: Kandakumar Murugesan, Nagaraj Raghavendra Rao, Saravanan Balakrishnan
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Publication number: 20230109863Abstract: In one aspect, compositions are described herein. A composition described herein comprises a nanoparticle, a therapeutic species, and a linker joining the nanoparticle to the therapeutic species. The linker joining the nanoparticle to the therapeutic species comprises a Diels-Alder cyclo-addition reaction product. Additionally, in some embodiments, the nanoparticle is a magnetic nanoparticle.Type: ApplicationFiled: December 7, 2022Publication date: April 13, 2023Inventors: Daniel J. HAYES, Mohammad ABU-LABAN
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Publication number: 20230109864Abstract: Provided are isolated polypeptides which are at least 80% homologous to SEQ ID NOs: 529, 475-528, 530-770, 6179-9796, 9798-10421, isolated polynucleotides which are at least 80% identical to SEQ ID NOs: 314, 1-313, 315-474, 771-6178, nucleic acid constructs comprising same, transgenic cells expressing same, transgenic plants expressing same and method of using same for increasing abiotic stress tolerance, yield, growth rate, biomass, vigor, oil content, photosynthetic capacity, seed yield, fiber yield, fiber quality, fiber length, and/or nitrogen use efficiency of a plant.Type: ApplicationFiled: November 3, 2022Publication date: April 13, 2023Applicant: Evogene Ltd.Inventors: Inbal Nurith DANGOOR, Hagai KARCHI
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Publication number: 20230109865Abstract: The present invention provides, inter alia, a process for producing a compound of formula (I) wherein the substituents are as defined in claim 1, comprising reacting a compound of formula (II) in a suitable reaction medium comprising a desulfurization agent formula (II). The present invention further provides intermediate compounds utilised in said process, and methods for producing said intermediate compounds.Type: ApplicationFiled: January 20, 2021Publication date: April 13, 2023Applicant: SYNGENTA CROP PROTECTION AGInventors: Raphael DUMEUNIER, Tomas SMEJKAL, Edouard GODINEAU
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Publication number: 20230109866Abstract: The disclosure relates to method for activating a fluid solenoid valve in a fluid system of a vehicle, in which, in order to set a switching mode, an activation voltage applied to a coil arrangement of the fluid solenoid valve. It is provided here that the activation voltage is set depending on an operating criterion to at least two different operating modes, wherein, in a first operating mode, a current regulation of the coil current flowing through the coil arrangement is performed, and in a second operating mode differing from the first operating mode.Type: ApplicationFiled: October 10, 2022Publication date: April 13, 2023Inventors: Andreas Teichmann, Christian Schrader
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Publication number: 20230109867Abstract: A speech recognition apparatus (2000) acquires source data (10) representing an audio signal including an utterance. The speech recognition apparatus (2000) converts the source data (10) into a text string (30). The speech recognition apparatus (2000) generates a concatenated text (40) representing a content of an utterance by concatenating a text (32) included in the text string (30). Herein, texts (32) adjacent to each other in the text string (30) are such that parts of associated audio signals overlap each other on a time axis. At a time of concatenating texts (32) adjacent to each other, the speech recognition apparatus (2000) eliminates a trailing portion of a preceding text (32) and a leading portion of a succeeding text (32).Type: ApplicationFiled: March 9, 2020Publication date: April 13, 2023Applicant: NEC CorporationInventors: Shuji KOMEIJI, Hitoshi YAMAMOTO
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Publication number: 20230109868Abstract: The present application discloses a semiconductor device. The semiconductor device includes a substrate; a plug structure including a bottom conductive layer positioned on the substrate, a middle conductive layer positioned on the bottom conductive layer, a top conductive layer positioned on the middle conductive layer, and an insulating covering layer covering a sidewall of the middle conductive layer and positioned between the bottom conductive layer and the top conductive layer; and a first dielectric layer positioned on the substrate and surrounding the plug structure. A width of the bottom conductive layer is greater than a width of the middle conductive layer. A width of the top conductive layer is greater than the width of the middle conductive layer.Type: ApplicationFiled: October 13, 2021Publication date: April 13, 2023Inventor: Tse-Yao HUANG
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Publication number: 20230109869Abstract: Provided are compositions for preventing or treating cancer including Asarum maculatum Nakai extracts, or a fraction thereof. According to an aspect, an Asarum maculatum Nakai extract has an excellent anticancer efficacy against various cancers including diffuse-type gastric cancer, and a cancer treatment agent having an excellent effect may be developed by using the extract as an active ingredient.Type: ApplicationFiled: October 7, 2022Publication date: April 13, 2023Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: Hak Cheol KWON, Jaeyoung KWON, Seong-Hwan KIM, Jung Hwan LEE, Jin Wook CHA, Ho Seong HWANG, Won Kyu KIM, Yujin KWON, Suyeon CHO, Taek Joo LEE, Jung Hwa KANG, Wan Hee LEE, Hyunki KIM
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Publication number: 20230109870Abstract: An aspect of the invention provides a method for analysing the Duchenne Muscular Dystrophy (DMD) gene in a sample containing genetic material of a subject, wherein the method detects the presence or absence of at least exons 7, 43, 44, 45, 46, 49, 50, 51, 52 and 54 of the DMD gene in the genetic material of the subject, wherein the detection of the presence or absence of the exons comprises multiplex polymerase-based nucleic acid amplification. Another aspect of the invention provides a method for analysing the DMD gene in a sample containing genetic material of a subject, wherein the method detects the presence or absence of at least exons 7, 43, 44, 45, 46, 49, 50, 51, 52 and 54 of the DMD gene in the genetic material of the subject, and wherein the sample is blood. Additional aspects of the invention provide tools applicable in the disclosed methods, such as primers, primer pairs, primer pair sets, oligonucleotide probes and probe sets, as well as compositions and kits containing the same.Type: ApplicationFiled: March 25, 2021Publication date: April 13, 2023Inventors: Pablo Beckers, François Boemer, Laurent Servais, Vincent Bours
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Publication number: 20230109871Abstract: The present invention provides methods and compositions for treating hyperlipidemia and/or hypercholesterolemia comprising administering to the subject an effective amount of an MTP inhibitor to inhibit hyperlipidemia and/or hypercholesterolemia in said subject, wherein said administration comprises an escalating series of doses of the MTP inhibitor. In some embodiments the method comprises administering at least three step-wise, increasing dosages of the MTP inhibitor to the subject. In some embodiments, the method further comprises the administration of one or more other lipid modifying compounds.Type: ApplicationFiled: December 9, 2022Publication date: April 13, 2023Inventor: Daniel J. RADER