Abstract: Embodiments are directed to a patch for coupling a watch body to a body of a user. The patch can include a substrate formed from a flexible material and an adhesive disposed over a surface of the substrate and configured to couple the patch to the body of the user. The patch can include a watch-mounting component disposed over a surface of the substrate and configured to couple the watch body to the patch. The patch can include one or more sensing elements, each having a terminal configured to contact the user, an interface element configured to interface with a watch sensing element of the watch body, and a conduit operably coupling the first terminal to the first interface element. The sensing elements can transmit signals to the watch body and the watch body can determine a physiological measurement of the user using the first and second signals.

Abstract: The present disclosure relates to a method for measuring multidimensional dynamics of cardiac activity comprising simultaneous measurement of three dimensional ECG, three dimensional impedance rheometry, tissue motion, wherein the tissue motion measurement is performed with a sensor placed outside the patient body selected from among sensors including: membrane, auscultation funnel, accelerometer, microphone, piezoelectric sensor, wherein the impedance rheometry measurement includes simultaneous generation of applied current of different frequencies for three orthogonal axes and an impedance measurement for the same or other three orthogonal axes, and wherein the impedance rheometry measurement and the ECG measurement are carried out for the same three orthogonal axes. The present disclosure further relates to a device for implementation of the method.

Abstract: A method for analyzing an acoustic signal having a time period and having a plurality of repeated audio patterns, has the following steps: receiving an audio signal having the acoustic signal; determining the audio patterns repeated within the acoustic signal; determining a window length for a plurality of windows, wherein the window length divides the time period of the acoustic signal into the plurality of windows; and windowing the acoustic signal to obtain the plurality of windows.

Abstract: Methods, systems, and devices for leveraging data from multiple data sources are described. A method includes receiving physiological data associated with a user from a wearable device and receiving additional data from an external device different from the wearable device, the additional data including at least data associated with characteristics of an environment associated with the user. The method further includes identifying one or more relationships between the collected physiological data and the characteristics of the environment associated with the user, and causing a graphical user interface (GUI) of a user device to display an indication of the one or more relationships, a message associated with the one or more relationships, or both. In some cases, the method includes causing the GUI to display instructions for selectively adjusting the one or more characteristics of the environment associated with the user based on the one or more relationships.

Abstract: One embodiment of the present invention includes a computer-implemented method that includes receiving spectral computed tomography (CT) volumetric image data. The spectral CT volumetric image data include data for at least two different energies and/or energy ranges. The spectral CT volumetric image data is processed with a machine learning engine configured to map spectrally enhanced features extracted from the spectral CT volumetric image data onto fractional flow reserve (FFR) values to determine a FFR value. The FFR value is then visually presented.

Abstract: A non-invasive and permeable RF diagnosis and treatment equipment and its catheter are provided. The catheter which comprises a tube body, a RF electrode array and a flexible protecting net has a retractable cavity, and the RF electrode array is attached to an outer surface of the retractable cavity; the flexible protecting net surrounding outside of the RF electrode array has a connector connected with the tube body and multiple holes. The retractable cavity has a smaller volume contraction state and a larger volume expansion state. Using the catheter, when inserting or pulling out the catheter, the RF electrode array will not contact the inner wall of the organ, but the flexible protecting net contacts the inner wall of the organ. In this way, the scratch of the inner wall of the organ caused by the RF electrode array can be minimized or even avoided through the flexible protecting net.

Abstract: The present invention relates to imaging a hollow organ. In order to provide an improved and facilitated imaging of a hollow organ of interest, a device (10) for providing three-dimensional data of a hollow organ is provided that comprises a measurement input (12), a data processor (14) and an output interface (16). The measurement input is configured to receive a plurality of local electric field measurements (18) of at least one electrode on a catheter inserted in a lumen of a hollow organ of interest. The measurement input is also configured to receive geometrical data (20) representative of the location of the at least one electrode inside the lumen during the measurements. The data processor is configured to receive pre-set electric field characteristics (22) associated with predetermined anatomical landmarks of the hollow organ expectable in the lumen in dependency of a type of the hollow organ.

Abstract: Methods, systems, and apparatus for signal artifact detection and reduction are provided. The signal artifact may comprise an interference between an electroencephalography (EEG) signal and a magnetic resonance imaging (MRI) signal arising out of simultaneous EEG and MRI treatment.

Abstract: Embodiments herein relate to ear-wearable systems and devices that can detect respiratory conditions and related parameters. In an embodiment, an ear-wearable device for respiratory monitoring is included having a control circuit, a microphone, and a sensor package. The ear-wearable device can be configured to analyze signals from the microphone and/or the sensor package and detect a respiratory condition and/or parameter based on analysis of the signals. In an embodiment, an ear-wearable system for respiratory monitoring is included having an accessory device and an ear-wearable device. In an embodiment, a method of detecting respiratory conditions and/or parameters with an ear-wearable device system is included. Other embodiments are also included herein.

Abstract: A non-invasive method and system is provided for determining an internal component of respiratory effort of a subject in a respiratory study. Both a thoracic signal (T) and an abdomen signal (A) are obtained, which are indicators of a thoracic component and an abdominal component of the respiratory effort, respectively. A first parameter of a respiratory model is determined from the obtained thoracic signal (T) and the abdomen signal (A). The first parameter is an estimated parameter of the respiratory model that is not directly measured during the study. The internal component of the respiratory effort is determined based at least on the determined first parameter of the respiratory model. The first model parameter is determined based on the thorax signal (T) and the obtained abdomen signal (A) without an invasive measurement.

Abstract: The present disclosure discloses a method for displaying a motion monitoring interface. The method includes: obtaining a movement signal during a motion of a user from at least one sensor, wherein the movement signal at least includes an electromyographic signal or an attitude signal; determining information related to the motion of the user by processing the movement signal; and displaying the information related to the motion of the user.

Abstract: An apparatus configured for application to a surface of a body, the apparatus comprising: an array of mechanomyography sensors spatially distributed across a substrate, each mechanomyography sensor configured to detect mechanomyography signals from the body to which the apparatus is applied; and a pressure bias system configured to provide a variation in contact pressure of the mechanomyography sensors to the body surface to receive mechanomyography signals at different levels of applied contact pressure.

Abstract: The invention relates to a sensor module (10) comprising a first submodule (101) comprising an electronic unit (105) for measuring and transmitting movement data, and a first structure (103), and a second submodule (201) comprising a fastening means for fastening the second submodule (201) to a wearer, and a second structure (205), wherein the first structure (103) can form a reversible mechanical connection with the second structure (205), with the result that the first submodule (101) and the second submodule (201) are reversibly connected to one another.

Abstract: A method and system of training a machine learning neural network (MLNN) in anatomical degenerative conditions in accordance with anatomical dynamics. The method comprises receiving, in a first input layer of the MLNN, from a millimeter wave (mmWave) radar sensing device, a first set of mmWave radar point cloud data representing a first gait characteristic of a subject in motion, comprising an arm swing velocity, receiving, in a second layer, a second set of mmWave radar point cloud data representing a second gait characteristic comprising a measure of dynamic postural stability, the input layers being interconnected with an output layer of the MLNN via an intermediate layer, and training a MLNN classifier in accordance with a classification that increases a correlation between a degenerative condition of the subject as generated at the output layer and the sets of mmWave point cloud data.

Abstract: Devices associated with on-body analyte sensor units are disclosed. These devices include any of packaging and/or loading systems, applicators and elements of the on-body sensor units themselves. Also, various approaches to connecting electrochemical analyte sensors to and/or within associated on-body analyte sensor units are disclosed. The connector approaches variously involve the use of unique sensor and ancillary element arrangements to facilitate assembly of separate electronics assemblies and sensor elements that are kept apart until the end user brings them together.

Abstract: A body fluid analyte detection apparatus is provided. Applying a force to a force applying portion of a bottom case in one direction can make the bottom case fail, and then separate the bottom case and a transmitter from each other. Before the bottom case is mounted to a human body, the bottom case is fixed together with a mounting unit by means of a snap-fit portion. Operation steps of a user when separating the bottom case from the transmitter are reduced, and the failure rate of the bottom case before being mounted to the human body is also reduced, thereby improving the user experience, and enhancing the reliability of the body fluid analyte detection apparatus.

Abstract: A body fluid analyte detection device, includes: a transmitter, provided with at least one first clamping part; a bottom shell, provided with a second clamping part corresponding to the first clamping part, the transmitter being assembled on the bottom shell by mutual snap fitting of the first clamping part and the second clamping part, the bottom shell including a fixing part and a force application part, and the fixing part being fixed and applying a force to the force application part in a direction to disable the bottom shell, so that the first clamping part and the second clamping part are separated from each other, and then the bottom shell and the transmitter are separated; a battery, used for supplying power to the transmitter; a sensor, used for detecting body fluid analyte parameter information and electrically connected to the transmitter to transmit a parameter signal.

Abstract: Implementations relate generally to devices for measuring an analyte in a host. Implementations may provide reduced sizes for wearable devices including a transcutaneous analyte sensor for analyte measurement.

Abstract: Implementations relate generally to devices for measuring an analyte in a host. Implementations may provide reduced sizes for wearable devices including a transcutaneous analyte sensor for analyte measurement.

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user’s interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract: Continuous Glucose Monitoring (CGM) devices provide glucose concentration measurements in the subcutaneous tissue with limited accuracy and precision. Therefore, CGM readings cannot be incorporated in a straightforward manner in outcome metrics of clinical trials e.g. aimed to assess new glycaemic-regulation therapies. To define those outcome metrics, frequent Blood Glucose (BG) reference measurements are still needed, with consequent relevant difficulties in outpatient settings. Here we propose a “retrofitting” algorithm that produces a quasi continuous time BG profile by simultaneously exploiting the high accuracy of available BG references (possibly very sparsely collected) and the high temporal resolution of CGM data (usually noisy and affected by significant bias).

Abstract: Methods and Devices to monitor the level of at least one analyte are provided.

Abstract: Disclosed is a device for transdermally detecting the concentration of one or more substances in a subject's bloodstream. The device includes a signal generation module arranged to generate microwave frequency signals at one or more discrete frequencies. The device also includes a sensor module comprising at least one microwave resonance sensor arranged to make contact with a subject's skin, the at least one microwave resonance sensor arranged to transmit microwave frequency signals generated by the signal generation module into the subject's body. The device also includes a signal processing module connected to the at least one microwave resonance sensor and arranged to: detect a resonance characteristic of the at least one microwave resonance sensor, and process the resonance characteristic to determine the concentration of one or more substances in a subject's bloodstream.

Abstract: Embodiments described herein include a device and a non-transitory computer-readable medium. The device includes one or more processors, an analyte sensor, a communication module, and memories. The processors are configured to generate analyte data indicative of a monitored analyte level measured by the analyte sensor corresponding to a first time, generate analyte data indicative of the monitored analyte level measured by the analyte sensor corresponding to a second time, calculate a correction parameter based on the analyte data corresponding to the analyte data corresponding to the first time and analyte data corresponding to the second time, and perform a lag correction to obtain the monitored analyte level using at least the calculated correction parameter. The calculated correction parameter comprises a lag time determined from the analyte data. The performed lag correction comprises a linear correction model based on the calculated correction parameter.

Abstract: Disclosed herein are systems, assemblies and methods of a sensor system that applies a correction factor to spectra information based on a force associated with a touch from a person applying the touch to the sensor system.

Abstract: A pulse oximetry system includes a wrist portion configured for placement on a wrist of a subject, the wrist portion having a first component and a second component configured to removably secure to one another. The wrist portion can include emitter(s) and detector(s) operably positioned by the wrist portion. In some implementations, the pulse oximetry system further includes a ring member configured to secure around the subject's finger and operably position emitter(s) and detector(s) and a cable connected to the wrist portion in electrical communication with the emitter(s) and the detector(s) of the ring member and configured to transmit the signal(s) from the detector(s) to the wrist portion. The system includes a battery and hardware processor(s) configured to receive and process signal(s) outputted by the detector(s) to determine physiological parameter(s) of the subject.

Abstract: Implementations relate generally to devices for measuring an analyte in a host. Implementations may provide reduced sizes for wearable devices including a transcutaneous analyte sensor for analyte measurement.

Abstract: A process for calibrating a glucose sensor under sterile conditions includes providing separate, sterile, glucose-containing calibration fluids, each having a different glucose concentration, and in turn providing these fluids to a sensing zone containing a sensing probe of a glucose sensor. Each solution is typically, in turn, propelled into the sensing zone, thus flushing out used fluid already present in the sensing zone. The process provides rapid calibration of a glucose sensor in a sterile fashion and is therefore appropriate for point-of-use calibration.

Abstract: A sampling unit includes a needle for aspirating a sample fluid, a housing, and a fitting. The needle includes a needle tip and a needle channel through the needle for guiding the aspirated sample fluid. The needle channel opens at the needle tip. The housing includes a housing cavity and a housing channel opening into the housing cavity. The fitting includes a fitting cavity and a fitting channel. The fitting is configured for sealingly receiving the needle tip into the fitting cavity and for being inserted into the housing cavity, so that the fitting channel on one side fluidically couples to the needle channel and on another side couples to the housing channel.

Abstract: An integrated peripheral intravenous (IV) catheter configured for blood draw both at the time of catheter placement and during catheter indwell. The peripheral IV catheter includes a catheter adapter having a catheter configured to be inserted into a patient's vasculature and a side inlet defining a fluid pathway into and out of the catheter. The peripheral IV catheter also includes a side port member having a main branch, the main branch including a distal end configured to couple the side port member to the side inlet of the catheter adapter and a connector portion accessible via a proximal end of the main branch. Additionally, the peripheral IV catheter includes a blood collection adapter removably and directly coupled to the connector portion of the side port member at the proximal end of the main branch. Furthermore, side pore member of the peripheral IV catheter may include a side branch.

Abstract: Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.

Abstract: A healthcare apparatus includes a BCG sensor; a camera; and a processor configured: to detect a ROI) corresponding to the face from the color facial image; to convert the detected first color image into a black and white image to acquire a first black and white image; to convert the detected second color image into a black and white image to acquire a second black and white image; to apply the acquired first black and white image and the acquired second black and white image to a predetermined trained algorithm model to output a remote photoplethysmography (rPPG) signal waveform of the subject; to calculate a first stress index based on the first heart rate variability; to calculate a second stress index based on the second heart rate variability; and to output a stress index of the subject based on the first stress index and the second stress index.

Abstract: An electronic device for providing biometric information is provided. The electronic device includes a sensor module, a memory, and a processor electrically connected to the sensor module and the memory. The processor obtains a biometric signal from the sensor module at a predetermined time interval, determines whether a user is in a first state on the basis of the obtained biometric signal, in case the user is in a first state, obtains a representative value for a respective of the at least one biometric signal, defines the obtained representative value for the respective of the at least one biometric signal as a candidate reference value for a corresponding biometric signal, determines a candidate reference value satisfying a predetermined condition as a first reference value for the corresponding biometric signal, and updates a second reference value previously configured for the corresponding biometric signal on the basis of the first reference value.

Abstract: A device including a magnetoresistance sensor for detecting a magnetic field from an ear cavity is disclosed. Methods for detecting a magnetic field from an ear cavity with a magnetoresistance sensor are also disclosed.

Abstract: A method and apparatus for measuring a biopotential signal together with impedance changes uses electrodes on a subject’s skin and for compensating for such impedances to increase accuracy and usability of such devices for short-and long-term monitoring of biosignals. The apparatus can include a first terminal for connection to a first electrode, a second terminal for connection to a second electrode, a first circuitry configured for measuring the biopotential signal from the first and the second terminal, a third terminal for connection to the reference skin electrode, a first variable controlled resistance load connected to the first terminal, and a second variable controlled resistance load connected to the second terminal.

Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.

Abstract: An electronic device and a wearable electronic device are provided in implementations of the disclosure. The electronic device includes a housing frame, a button assembly, and a circuit assembly. The housing frame has an inner cavity and a first through hole. The first through hole communicates with the inner cavity and an external space outside the housing frame. The button assembly includes a first conductive member and a second conductive member. The first conductive member is connected to the housing frame and at least partially in the external space. The second conductive member is at least partially in the first through hole. The first conductive member elastically abuts against the second conductive member, so that the first conductive member is in electrical communication with the second conductive member. The circuit assembly is disposed in the inner cavity.

Abstract: A measurement station includes a base including a measurement plate having an upper surface adapted to receive a user's feet, a handle support, mounted on the upper surface of the measurement plate, a handle adapted to receive a user's hands, the handle being configured to be received on the handle support.

Abstract: A measurement station includes an electrocardiogram acquisition system, two control electrodes configured to contact a user, and an electrical connection circuit, the electrical connection circuit comprising a feedback loop connected to the two control electrodes.

Abstract: A brush electrode includes an electrode base that is connectable to an external device that is configured to generate an electrical signal or receive an electrical signal. A plurality of strand electrodes extend outward from the electrode base. A distal end of each strand electrode is configured to contact a skin surface. The strand electrodes are configured to hold an electrolyte to facilitate ionic conduction of the electrical signal to or from the skin surface.

Abstract: A partially-masked electrode includes a conductive material and an insulated coating having an outer surface. The insulated coating defines a contoured opening that exposes or reveals an area of the conductive material, wherein the contoured opening has an upper perimeter at the outer surface of the insulated coating. When the upper perimeter of the insulated surface coating is placed in contact with a tissue of interest, wherein the tissue of interest is proximate a blood pool, the insulated coating creates a seal between the blood pool and the contoured opening so that no blood in the blood pool can contact the conductive material. This seal reduces or eliminates the reception of far field effects in the blood pool by the electrode, making it easier to locate and diagnose unhealthy tissue.

Abstract: Example apparatuses disclosed herein are generally usable with catheter-based systems to measure or provide electrical signals within the heart and surrounding vasculature. Example apparatuses generally include an end effector with one or more spines that can rotate about a longitudinal axis such that the spines are aligned in a plane in a first configuration and the one or more spines are rotated out of the plane in a second configuration. The end effector can include features which provide improved and/or alternative diagnostic or treatment options compared to existing end effectors. In some example treatments utilizing some example apparatuses presented herein, an end effector can map a wall within the heart in the first configuration and a lumen of a vein in the second configuration.

Abstract: A defibrillator is an apparatus for defibrillation, and includes an oxygen saturation (TOI) measurement unit for acquiring a numerical value related to an oxygen saturation of a patient, an electrocardiogram (ECG) measurement unit for measuring an electrocardiogram of the patient in order to determine whether an electrical shock is required for the patient, and a control unit for starting measurement of the electrocardiogram of the patient in the electrocardiogram measurement unit on the condition that the numerical value acquired in the oxygen saturation measurement unit exceeds a threshold value.

Abstract: The present disclosure is directed to a solid body for a biomedical device, wearable by a patient and configured to acquire one or more physiological parameters of the patient. The solid body includes a first rigid portion, a second rigid portion and a connection portion of flexible type which couples the first and the second rigid portions to each other; and a control circuitry accommodated inside the first and/or the second rigid portions. The connection portion is interposed between the first and the second rigid portions, is integral therewith and is deformable so as to allow a relative movement of the first and the second rigid portions. The first and the second rigid portions are physically couplable to a first and to a second ECG electrode to couple the solid body to the torso of the patient.

Abstract: An animated electrophysiology map is generated from a plurality of data points, each including measured electrophysiology information, location information, and timing information. The electrophysiology and location information can be used to generate the electrophysiology map, such as a local activation time, peak-to-peak voltage, or fractionation map. Animated timing markers can be superimposed upon the electrophysiology map using the electrophysiology, location, and timing information. For example a series of frames can be displayed sequentially, each including a static image of the electrophysiology map at a point in time and timing markers corresponding to the state or position of an activation wavefront at the point in time superimposed thereon. The visibility or opacity of the timing markers can be adjusted from frame to frame, dependent upon a distance between the timing marker and the activation wavefront, to give the illusion that the timing markers are moving along the electrophysiology map.

Abstract: In one exemplary mode, a medical system includes a catheter to be inserted into a chamber of a heart of a living subject, and including a distal end including catheter electrodes to contact tissue at respective locations within the chamber of the heart, at least one position sensor to provide at least one position signal indicative of at least one position of the distal end, a display, and processing circuitry to assess respective qualities of contact of the catheter electrodes with the tissue, compute positions of respective ones of the catheter electrodes responsively to the at least one position signal, generate a 3D anatomical map of at least part of the chamber of the heart responsively to the assessed respective qualities of contact and the computed positions of the respective ones of the catheter electrodes and render to the display the generated 3D anatomical map.

Abstract: In described embodiments, a device and method for diagnosing brain and neurological issues is provided. The device measures the performance of Convergence, Divergence, and binocular tracking capabilities of a subject's eyes, which can be used to determine whether a subject has experienced a brain or other neurological event.

Abstract: The embodiments of the present disclosure provides a device for determining muscle state based on electromyography signal and muscle oxygen saturation. The devices includes: a signal collection module, configured for collecting a human electromyography signal data; a light source detection module, configured for emitting light with different wavelengths; a photosensitive receiver module, configured for receiving light reflected by skin after the light emitted by the light source detection module irradiates the skin; a blood oxygen calculation module, configured for calculating the muscle oxygen saturation based on the light received by the photosensitive receiver module; and a data statistics module, configured for determining the muscle state based on the human electromyography signal data and the muscle oxygen saturation. In this way, an accurate detection of muscle state is realized.

Abstract: In order to determine a degree of dementia of a user, contents are output through a user terminal, a voice of the user for a content acquired by a microphone of the user terminal is received, a spectrogram image is generated by visualizing the voice, and the degree of dementia of the user is determined by means of a convolutional neural network (CNN) and a deep neural network (DNN) based on the spectrogram image.

Abstract: A brain image analysis apparatus (2000) acquires input data (40) including a structural brain image (42) and a functional brain image (44) for a subject (10). The brain image analysis apparatus (2000) obtains analysis data (20) by inputting the input data (40) into an analysis model (2020). The analysis model (2020) has been trained in advance so as to output the analysis data (20) representing information about brain dysfunction in response to an input of the input data (40). The brain image analysis apparatus (2000) outputs, based on the analysis data (20), output data (30) representing information about the brain dysfunction of the subject (10).