Abstract: An apparatus, comprising an inflatable member, a pump configured to transfer fluid to the inflatable member, and a housing operatively coupled to the inflatable member and to the pump. The housing defining a cavity. The housing including a base member disposed within the cavity defined by the housing and a sealing member disposed within the cavity defined by the housing. The sealing member being configured to move with respect to the base member.

Abstract: The invention provides a filter assembly including a string or wire such that a lasso type cincture is effected, said filter being openable and closeable while in deployed within a bodily vessel. A string lengthen or shorting adjustment mechanism, such as a ratchet or reel allows more length of string into the device or alternatively to shorten the length of available string in the system. The described invention, when used to ameliorate venous clots and most arterio-venous dialysis grafts, a filter-tipped aspirator is used downstream from the clot to capture and remove dislocated emboli. A method of using same is disclosed.

Abstract: A method comprises obstructing at least a portion of an inside of a gallbladder using a barrier, and suppressing, using the barrier, contacting at least a portion of an interior wall of the gallbladder with a bile from a cystic duct.

Abstract: A device includes a first end portion, a second end portion, an intermediate portion, and a graft material. The first end portion has a first end diameter. The second end portion has a second end diameter smaller than the first end diameter. The first end portion comprises a first material. The second end portion comprises a second material different than the first material. The intermediate portion is between the first end portion and the second end portion. The intermediate portion tapers between the first end portion and the second end portion. The graft material is coupled to at least the intermediate portion.

Abstract: Plunger apparatus comprising a housing, a plunger, a source of stored mechanical energy, a rotatable element and an actuator. Rotation of the rotatable element provides a controlled release of the plunger for the movement of the plunger, under force provided by the source of stored mechanical energy. The actuator allows operation, by an operator, of the plunger apparatus to induce rotation of the rotatable element relative to the housing to provide a controlled release of the plunger for axial movement of the plunger under the force provided by the source of stored mechanical energy.

Abstract: A prosthetic heart valve can have one or more hermetic layers. The inner skirt and/or the outer skirt can comprise one or more hermetic layers, or the entire valve frame can be encapsulated within one or more hermetic layers. Each hermetic layer can be substantially nonporous or can have pores therein that are sized to discourage cellular ingrowth. The hermetic layer can prevent ingrowth of surrounding native tissue, thereby reducing pannus formation on the prosthetic leaflets. Alternatively or additionally, shapes of the leaflets of the valvular structure of the prosthetic valve and/or the coupling of the leaflets to the valve frame can be selected to avoid the incidence of stasis when implanted at a relatively low pressure gradient hemodynamic location. Such a prosthetic heart valve may reduce the risk of thrombosis.

Abstract: A method of assembling a valvular structure can include folding an upper tab of a first leaflet onto a lower tab of the first leaflet, disposing a first end of a reinforcing member on the upper tab, disposing a commissure member adjacent the lower tab, and coupling the first end of the reinforcing member, the tabs of the first leaflet, and the commissure member to one another. The method can further include folding an upper tab of a second leaflet onto a lower tab of the second leaflet, disposing the second leaflet adjacent the first leaflet such that the commissure member is positioned between the lower tabs, disposing a second end of the reinforcing member on the upper tab of the second leaflet, and coupling the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another to form a commissure.

Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff. At least one runner is coupled to a cell and configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition.

Abstract: A prosthetic heart valve includes a stent extending in a longitudinal direction and having a collapsed condition and an expanded condition. The stent includes a plurality of struts forming cells and a plurality of commissure attachment features spaced apart in an annular direction of the stent and extending in a medial direction of the stent. A valve assembly is secured to the commissure attachment features, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge and being capable of alternating between an open position and a closed position. A method of manufacturing the prosthetic heart valve is also provided.

Abstract: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. As one example, the sealing member includes a knitted fabric layer, the knitted fabric layer comprising a base layer forming an inner surface of the knitted fabric layer, where the base layer has a mesh-like structure. The knitted fabric layer further comprises a plush outer surface comprising a plurality of pile yarns knit into loops and that extend outward from the base layer.

Abstract: A prosthetic valve delivery apparatus can comprise a handle, an outer shaft extending distally from the handle, a gear mechanism arranged distal to the outer shaft, an input torque shaft extending distally from the handle through the outer shaft and having a distal end portion operatively connected to the gear mechanism, and a plurality of output torque shafts operatively connected to and extending distally from the gear mechanism. The gear mechanism is configured to transfer rotational motion from the input torque shaft to the plurality of output torque shafts.

Abstract: The expandable sheaths disclosed herein include an expandable outer layer and a generally non-expandable inner layer. The outer layer is movable between a non-expanded configuration and an expanded configuration, where the outer layer/tubular layer is biased to the non-expanded configuration. Receipt of the inner layer within the central lumen of the outer layer causes the outer layer to transition from the non-expanded configuration to the expanded configuration.

Abstract: An introducer sheath system is disclosed herein that includes an introducer locking hub, an introducer coupled to the introducer locking hub, and a hypotube disposed within the central lumen of the introducer. The introducer locking hub prevents axial and rotational translation of the introducer with respect to the sheath. The introducer defines an elongated body having a proximal piece and a separate distal piece, the proximal piece coupled to the introducer locking hub and the distal piece coupled to the distal end of the hypotube. The body portion of the hypotube is slidably disposed within the central lumen of the proximal piece of the introducer such that movement of the hypotube within the central lumen of the proximal piece causes the distal piece of the introducer to move with respect to the proximal piece.

Abstract: Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and/or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.

Abstract: Coaptation-assist devices (20) are provided for treating a native atrioventricular valve. The coaptation-assist devices (20) include a ventricular anchor (30), which includes one or more wires (35), and which is configured to be positioned in a ventricle; and a neo-leaflet (32), which is supported by the ventricular anchor (30) and is configured to at least partially replace function of a target native leaflet of the native atrioventricular valve by providing a surface of coaptation (34) for one or more opposing native leaflets. In some configurations, the ventricular anchor (30) includes a proximal subannular anchor (54), which includes a digitate anchor (56) that is shaped so as to define a plurality of fingers (60) having a plurality of curved superior peaks (66) that point in a superior direction and engage a subannular surface of the target native leaflet. Other embodiments are also described.

Abstract: Anchoring assemblies that increase the surface area and/or amount of anchored tissue include a barb anchor, translatably disposed within the opening of an anchor housing, the barb anchor comprising a barb arm, the barb arm including a linear configuration wherein the barb arm is aligned with an axis of the opening and a deflected configuration wherein at least a portion the barb arm is deflected away from a central axis of the opening of the anchor housing.

Abstract: A delivery catheter is in various embodiments configured to deliver an anchoring device to a native valve annulus of a patient's heart, where the anchoring device can better secure a prosthesis at the native annulus. The delivery catheter may include a flexible portion configured to form a spiral shape in embodiments.

Abstract: A delivery catheter is in various embodiments configured to deliver an anchoring device to a native valve annulus of a patient's heart, where the anchoring device can better secure a prosthesis at the native annulus. A sheath catheter may be utilized to deliver the delivery catheter and a catheter for deploying a prosthetic valve to the anchoring device.

Abstract: An implantable inflatable device includes a fluid reservoir defining a cavity, an inflatable member, a pump assembly configured to transfer fluid from the fluid reservoir to the inflatable member, and a programmable control module, the programmable control module being configured activate the pump assembly to transfer fluid from the fluid reservoir to the inflatable member.

Abstract: A scaffold comprised of a plurality of PLLA layers, which may include stem cells, for regenerating bone or tissue. The PLLA layers are separated by a plurality of hydrogel layers. The PLLA layers comprise a nanofiber mesh having a piezoelectric constant to apply an electrical charge to the bone or tissue upon application of ultrasound energy.

Abstract: A method for manufacturing an implantable device is provided. The method includes laser nano-texturing a titanium surface. The method further includes applying an aqueous silver ion solution to form a silver ion complex on the nano-textured titanium surface. The method also includes reducing, using laser-assisted photocatalytic reduction, the silver ion complex to silver ion particles which are immobilized on the nano-textured titanium surface.

Abstract: There is disclosed herein radial head elbow prosthesis which is anatomically designed to improve anatomical conformity and function and reduce likelihood of dislocation. Depression centroid eccentricity and orientation and raised lateral bearing surface aspects of the present radial head improve tracking of the radial head prosthesis of the capitellum and reduce likelihood of dislocation thereof.

Abstract: A method for securing a stemless humeral includes positioning the stemless humeral anchoring component to the humerus such that a lateral anchoring wing extends in a direction of a lateral side of the humerus into a lateral region and two medial anchoring wings face a medial side of the humerus in a medial region. The lateral region has a lower bone density relative to the medial region. The stemless humeral anchoring component is positioned eccentrically such that the anchoring stud and the two medial anchoring wings are anchored in the medial region. The stemless humeral anchoring component is secured in resected proximal epiphyseal and metaphyseal portions of the humerus without reaching a diaphyseal portion of the humerus.

Abstract: A bone fusion implant is provided for treating conditions of Proximal Interphalangeal (PIP), Distal interphalangeal (DIP), and metatarsophalangeal (MTP) foot joints. The bone fusion implant may be a cortical bone allograft sized to fuse the foot joint to be treated. A proximal portion of the implant may be pressed into a hole drilled in a proximal bone portion of the foot joint, and a distal portion of the implant may be pressed into a hole drilled in a distal bone portion of the foot joint. Ramps on the proximal and distal portions facilitate press-fitting the implant into the holes in the bone portions. Side ramps ensure that the bone fusion implant remains substantially aligned with the foot joint while the distal portion is pressed into the hole into the distal bone portion. Grooves on the ramps alleviate pressure and ease inserting the implant into the holes in the bone portions.

Abstract: Bone implants, including methods of use and assembly. The bone implants, which are optionally composite implants, generally include a distal anchoring region and a growth region that is proximal to the distal anchoring region. The distal anchoring region can have one or more distal surface features that adapt the distal anchoring region for anchoring into iliac bone. The growth region can have one or more growth features that adapt the growth region to facilitate at least one of bony on-growth, in-growth, or through-growth. The implants may be positioned along a posterior sacral alar-iliac (“SAT”) trajectory. The implants may be coupled to one or more bone stabilizing constructs, such as rod elements thereof.

Abstract: An expandable spinal fusion implant including first and second endplates coupled to an expansion member that sits within a housing. The expansion member is translated by a drive mechanism, whereby translation of the expansion member by the drive mechanism in a distal and proximal directions causes the distance between the endplates to increase and decrease, respectively.

Abstract: An interbody cage for the spinal column structured as a scaffold made of at least two folding and unfolding scaffoldings: one base member (also named a cage body) which receives the pivoting means of a pivoting member (also named an extension member), and one extension member, structured to pivot around an axis on the cage body from a first folded or stowed configuration to a second unfolded or deployed configuration such that the perimeters of the contact surfaces between the interbody cage and the vertebrae and/or the height of the interbody cage increase from the stowed configuration to the deployed configuration.

Abstract: Methods, apparatuses, and systems for robotic insertion of a screw, a rod, or another component of a surgical implant into a patient are disclosed. Synchronous insertion of screws is performed by multiple surgical robots or a single surgical robot having multiple arms and end effectors. The movements of each robotic arm are coordinated into position in preparation of the insertion of multiple surgical implant components at the same time or in the same surgical step. The insertion of the surgical implant components is performed while monitoring the insertion progress. The insertion is completed autonomously or in coordination with a surgeon.

Abstract: Tibial implants, instruments, systems, and methods of implanting a tibial tray during a knee arthroplasty. The inserter instrument may include a main body with a pair of fixed posterior tabs, a moveable anterior tab body with an anterior tab, and a rotatable shaft for controlling movement of the anterior tab body. When the shaft is rotated, the anterior tab body is translated into an expanded position to lock the inserter to the tibial tray, thereby providing precise positioning of the tibial tray during implantation.

Abstract: Provided is a method for converting a modular anatomic shoulder implant to a modular reverse shoulder implant, wherein the modular anatomic shoulder implant and the modular reverse shoulder implant have novel configurations.

Abstract: A device for shaping and cutting a bone graft comprises a main body (2) extending along a longitudinal axis (X) from a lower end (2i) to an upper end (2s) and having inside it a housing (3) for the insertion of the bone graft (100) to be shaped, an upper opening (4), located at the upper end (2s), for the insertion of the bone graft (100) into the housing (3), a lower support (5) designed to support the bone graft and an upper surface (6) defining a cutting plane, placed at the upper end (2s) and containing said upper opening (4) which is inclined with respect to the longitudinal axis (X) by an angle (a) ranging between 90° and 30°, preferably between 90° and 60°.

Abstract: Disclosed herein is a joint implant including a first implant coupled to a first bone of a joint, and a second implant coupled to a second bone of the joint and contacting the first implant. The second implant can include a plurality of sensors configured to measure data and a processor operatively coupled to the plurality of sensors and adapted to receive the data from the sensors. The processor can be configured to communicate with a neural network and a channel detector adapted to exclude a first portion of the data received from the processor and output a second portion of the data.

Abstract: Disclosed herein are methods for determining kinematic information of a joint. A method according to one embodiment may comprise the steps of receiving data obtained from a sensor of an implanted joint implant, analyzing the data with a trained estimation model to simultaneously determine kinematic information of the joint in six degrees of freedom, and outputting the kinematic information. In another embodiment, a method may comprise the steps of applying data obtained from a Hall sensor of an implanted joint implant to a trained estimation model to simultaneously determine kinematic information of the joint in six degrees of freedom; and outputting the kinematic information.

Abstract: An orthopedic measurement system is disclosed to measure leg alignment. The measurement system includes a tri-axial gyroscope configured to measure movement of a leg. The gyroscope is coupled to a tibia of the leg. For example, the gyroscope can be placed in an insert or tibial prosthetic component that couples to the tibia. The gyroscope is used to measure alignment relative to the mechanical axis of the leg. The leg alignment measurement is performed by putting the leg through a first leg movement and a second leg movement. The gyroscope outputs angular velocities on the axes the sensor is rotated about. The gyroscope is coupled to a computer that calculates the alignment of the leg relative to the mechanical axis from the gyroscope measurement data.

Abstract: The invention relates to an orthopaedic joint device, comprising an upper part (2) and a lower part (3), which are mounted on one another so as to be pivotable about a joint pin (4) and between which a damper device (5) is situated in order to provide resistance against pivoting of the upper part (2) relative to the lower part (3), and the damper device (5) is mounted on the upper part (2) and the lower part (3) via fastening devices (6, 7), a fastening device (6) comprising a head (8) in which a bearing (9) is situated which is supported on a pin (10) that is mounted in the upper part (2) or lower part (3), characterised in that the pin (10) is mounted so as to be rotatable in the upper part (2) or lower part (3).

Abstract: The invention relates to a method for controlling a prosthesis or orthesis of the lower extremity, which prosthesis or orthesis comprises an upper part (10) and a lower part (20) that is connected to the upper part (20) via a knee joint (1) and is mounted so as to be pivotable relative to the upper part (10) about a joint pin (15); wherein an adjustable resistance device (40) is situated between the upper part (10) and the lower part (20), by means of which resistance device a flexion resistance (Rf) in an early and middle standing phase is modified, during walking, on the basis of sensor data, following initial heel contact up to the middle standing phase; wherein, following the initial heel contact, the flexion resistance (Rf) is increased to a value at which further flexion is blocked or at least slowed; wherein the progression over time of the flexion resistance increase and/or the maximum achievable flexion angle (Af) is modified on the basis of the inclination of the ground or a height difference (?H) t

Abstract: A knee prosthesis system including a knee prosthesis, an actuator and a controlling unit. The knee prosthesis includes a thigh segment and a shank segment. The actuator rotatably connects the shank segment and the thigh segment. The actuator is configured to controllably assume a powered knee behavior to generate knee motion or a passive knee behavior to resist knee motion. The controlling unit includes a finite-state control structure. The controlling unit electrically communicates with the actuator. The control structure includes at least three passive states and at least one powered state. The passive states include a passive stance-resistance state, a swing-flexion state, and a swing-extension state and the at least one powered state includes at least one of a swing-assistance state, a stance-assistance state, and a powered-swing state.

Abstract: Prosthetic coupling interfaces and methods of use are disclosed herein. An example system can include an external fixator apparatus, a prosthetic appendage assembly, and a prosthetic coupling interface for connecting the external fixator apparatus with the prosthetic appendage assembly.

Abstract: A prosthetic system includes a prosthetic foot with a foot member defining a first end portion, a second end portion, and an intermediate portion defining a curvature and extending between the first and second end portions. A pump mechanism is coupled to the foot member. The pump mechanism includes a housing defining a cavity, and a membrane situated in the cavity. The pump mechanism is movable between an original configuration and an expanded configuration. A movable member includes a first portion coupled to the membrane and a second portion arranged to slidably engage the foot member. Relative movement between the first and second end portions moves the first portion of the movable member relative to the housing and slides the second portion along a length of the foot member to shift the pump mechanism between the original and expanded configurations.

Abstract: Disclosed is an intravascular indwelling stent that include a stent main body and a polymer film covering the stent main body. Through-holes are formed in the polymer film. The through-holes connect an inside and an outside of a cylinder of the intravascular indwelling stent to each other and each have an opening size of 0.02 mm or more and 0.2 mm or less. An opening occupancy, which is the ratio of the opening area of all the through-holes included in a unit area of the outer surface of the polymer film to the unit area, is 25% or more and 41% or less. A surface density of boundary, which is the ratio of the length of opening edges of all the through-holes included in a unit area of the outer surface of the polymer film to the unit area, is 9.5/mm or more and 30/mm or less.

Abstract: The present disclosure provides with a device for temporary residence in a stomach of a subject, the device carrying a load of an active pharmaceutical ingredient and having an expanded configuration. When the device is positioned in the stomach and in the expanded configuration, the device is configured to be retained in the stomach of the subject, and for releasing at least partially the active pharmaceutical ingredient while allowing chyme flow. The device is further configured to transfer from the expanded configuration into an emptying configuration in which the device is configured to pass through the pyloric valve. This enables dispensing locally therapeutic substances at a gastric region of a human body.

Abstract: A method for performing a medical procedure may comprise advancing a first device through a first body lumen. A distal portion of the first device may include a magnet. The method may further comprise advancing a second device through a second body lumen. The second device may include a magnetic field sensor. The method may further comprise receiving a signal from the magnetic field sensor. The signal may be indicative of a magnetic field measured by the magnetic field sensor. The method may further comprise, if the received signal matches a magnetic field of the magnet, identifying a position of the magnet.

Abstract: A device (100) includes a leg engaging section (101) and a foot engaging section (102) intersecting at a heel receiver (103). The leg engaging section and the foot engaging section define a leg insertion aperture (104). A compressible cushion layer (402) is disposed at least in the leg engaging section. At least one bolster tube (401) is disposed interior the leg engaging section. The bolster tube (401) can be selectively removable through one or more apertures (1105,1106).

Abstract: A lower extremity orthosis includes a foot engagement portion and an elongated positioning member. The foot engagement portion is configured to engage a patient's foot and includes opposing sidewalls extending from a sole-supporting surface configured to engage with a sole of the patient's foot. The elongated positioning member includes a foot-underlying portion and a lower leg-underlying portion, with the foot-underlying portion of the elongated positioning member serving to couple the elongated positioning member to the foot engagement portion. The lower extremity orthosis may be selectively and removably engaged with a heel offloading device via the lower leg-underlying portion of the elongated positioning member, such that the lower extremity orthosis is configured to prevent or reduce plantar flexion when the heel offloading device is used and the lower extremity orthosis is applied to the patient's foot.

Abstract: A therapeutic orthopedic device is described. The orthopedic device serves to restrain and limit movement of a human arm and shoulder. The device comprises a torso pillow, a padded forearm support attached to the pillow and a shoulder strap that traverses the clavicle region of the opposite shoulder. The pillow is positioned to rest against the torso of a user and the strap is positioned over the opposite shoulder. The forearm support acts as a shelf upon which the user’s forearm may rest in a natural position. Flexible straps extend from the forearm support, over the user’s forearm, and engage with the pillow to secure the forearm.

Abstract: According to an aspect, an implantable device includes a fluid reservoir configured to hold fluid, an inflatable member configured to be implanted in a body of a patient, and an electronic pump assembly. The electronic pump assembly includes a controller configured to actuate at least one of a pump or an active valve to inflate the inflatable member, and a pressure sensor configured to monitor a pressure of the inflatable member. The controller is configured to detect a value of at least one at least one fluid transfer parameter for the pressure of the inflatable member to reach a target pressure during an inflation cycle. The controller is configured to generate size capability information of the inflatable member for the patient based on the detected value of the at least one fluid transfer parameter.

Abstract: A method for assembling a drain assembly for draining an ostomy bag and a method for a method for draining an ostomy bag. The method includes providing a connector configured to attach to the ostomy bag. A flexible conduit is connected to the connector and a discharge valve is connected with a distal end of the flexible conduit from the connector. The flexible conduit includes sufficient length and sufficient flexibility to permit an ostomy bag wearer to position the discharge valve into a discharge position outside of the ostomy bag wearer’s clothing for discharge of urine waste from the ostomy bag.

Abstract: A male urinary incontinence device (10) comprising a proximal wall (20) and a distal wall (30) being sealed together at the periphery to form an inner cavity (70), the proximal wall comprises a through-going inlet opening (25) through which a penis can be entered, the inner cavity adapted to contain at least a part of the penis, and wherein the distal wall comprises a second opening (35) configured for allowing access to the inner cavity, the through-going inlet opening comprises a circular shape, and where the through-going inlet opening (25) is positioned symmetrically at a longitudinal central axis X defined by a line of symmetry in radial direction of the device.

Abstract: The present invention discloses a disposable male hygiene product for a user during urination includes an elongated strip bend at a middle position to form two side arms, a non-separable pocket at an outer portion of an open end of each of the two side arms to insert at least two fingers or a thumb and a finger inside the non-separable pocket of each of the two side arms, wherein the disposable hygiene product is made of a liquid absorbing material that absorbs urine residue after the urination and provides a human contactless support to a penis during urination when a user holds the penis using the disposable hygiene product by inserting at least two fingers or a thumb and a finger inside the non-separable pocket of the two side arms.

Abstract: A wearable urinary collection apparatus includes an elongate, tubular, flexible, collection receptacle which receives and stores urine therein, a constriction formed at an intermediate position of the collection receptacle which defines a constricted opening at the intermediate position such that the urine which a user discharges into the collection receptacle must pass through the constricted opening, a short tubular member having opposite open ends and a diameter which is smaller than a diameter of the collection receptacle and having one of opposite open ends connected at the constriction in alignment with the constricted opening, and a check valve provided at the one of the opposite open ends of the tubular member adjacent to the constricted opening and which is configured to permit urine to freely pass from the constricted opening into the tubular member, and to block urine from flowing from the tubular member into the constricted opening.