Abstract: The present invention describes a tall diesel composition obtainable from a crude tall oil, said tall diesel composition comprising carboxylic acids in a range of 50-98 wt % and neutral components in a range of 2-50 wt %, wherein the tall diesel composition comprises 1-20 wt % rosin acids, 6-35 wt % saturated fatty acids and 59-74 wt % unsaturated fatty acids.

Abstract: The present disclosure relates generally to processes and systems for producing liquid transportation fuels by converting a feed stream that predominantly comprises isobutane. The feed stream is catalytically-activated in two separate reaction zones arranged in series in a manner that minimizes the production of C1-C3 light paraffins and is tolerant to the presence of typical catalyst poisons. The first reaction zone is selective for conversion of the feed stream to predominantly olefins and some aromatics. The second reaction zone is maintained at a lower temperature and a higher pressure and is selective for converting olefins to monocyclic aromatics which facilitates further feed stream olefination. Certain embodiments contact the activation effluent with an alkylation catalyst to provide enhanced yields of upgraded hydrocarbon products that meet specifications for a transportation fuel blend component.

Abstract: A fire resistant paper machine oil comprising a blend of oil soluble base and water insoluble base having the formula: 0-100 wt % Oil Soluble PAG (Polyalkylene Glycol); 0-100 wt % Polyol Ester; an anti-wear additive; rust inhibitor; hindered phenolic anti-oxidant; alkylated di phenyl amine anti-oxidant; and, foam inhibitor. A blend of the base oils are the most preferred embodiment, however, a product could be formulated using only one type of base material such as an oil soluble base or a water insoluble base.

Abstract: A fluorine-containing ether compound represented by the following formula (1) is provided. R2—CH2—R1—CH2OCH2CH(OH)—(CH2)n—CH(OH)CH2OCH2—R1—CH2—R2??(1) (in the formula (1), n is an integer of 2 to 6, R1 is a perfluoropolyether chain, R2 is —OCH2CH(OH)CH2O(CH2)mOH (m in the formula is an integer of 2 to 4)).

Abstract: A medical device, an elastically deformable functional part for a medical device, and a method for sterilizing and/or for establishing sterilization resistance of a medical device or an elastically deformable functional part. The elastically deformable functional part has an openable slit arrangement that widens or opens upon elastic deformation of the elastically deformable functional part and recloses upon cessation of the elastic deformation. The slit wall faces of the slit arrangement are coated with a composition that includes a silicone oil and a thickener.

Abstract: The present disclosure relates to a driveline for an electric or hybrid-electric vehicle including an electric motor with an insulated magnet wire and a lubricating and cooling fluid configured to maintain the durability of the magnet wire.

Abstract: Present invention relates to a process for reducing the MOSH and/or MOAH content from vegetable oil selected from the group consisting of palm-based oil, cocoa butter-based oil and any mixtures thereof, and comprising steps of: a) subjecting the vegetable oil to a short-path evaporation, wherein the short-path evaporation is performed at a pressure of below 1 mbar, at an evaporation temperature in a range of from 235 and 290° C., and with a feed rate per unit area of evaporator surface of the shorth-path evaporation equipment in a range of from 35 to 102 kg/h·m2, and thus obtaining a retentate vegetable oil and a distillate, b) Contacting the retentate vegetable oil with an adsorbent, and c) Subjecting the bleached retentate vegetable oil to a further refining step.

Abstract: A process is disclosed for the production of solvents and/or lubricants from renewable sources, comprising the steps of fat hydrolysis and an esterification reaction of the fatty acids with alcohols in the presence of zinc oxide. To the product of the fatty acid esterification reaction, a non-solvent is added, obtaining a precipitate that is separated from the product and used as a catalyst in the previous hydrolysis step of the fats used as a raw material. In one embodiment, said process also provides an acidification step of waste soaps and surfactants. In one embodiment, the precipitate used as a catalyst in the fat hydrolysis step can be used as a catalyst also in the fatty acid esterification reaction.

Abstract: A method of making a candle, including placing wax in a heat-resistant container; placing the heat-resistant container in the pot that includes water, wherein the heat-resistant container is smaller than a pot that includes water; heating the water in the pot until the small chunks, shavings, layers or portions melt to form a melted wax mixture; adding hemp oil, cannabidiol (CBD) oil or tetrahydrocannabinol (THC) oil to the scented melted wax mixture to create a hemp, CBD or THC melted wax mixture; placing a wick in a center of the heat-resistance container; pour the hemp, CBD or THC melted wax mixture into a candle mold container; allow the hemp, CBD or THC melted wax mixture to cool in the candle mold container to for a hemp, CBD or THC candle; and remove the candle mold container from the hemp, CBD or THC candle from the candle mold container.

Abstract: A fabric care formulation is provided, comprising: a liquid carrier; and a plurality of composite opacifier particles, wherein the composite opacifier particles comprise metal oxide particles that are partially or completely encapsulated by a wax; wherein the metal oxide particles are selected from the group consisting of zinc oxide, titanium oxide and mixtures thereof; wherein the metal oxide particles have a z average particle size of >100 nm as measured by dynamic light scattering; wherein the wax has a melting point temperature of 45 to 110° C.; and wherein the composite opacifier particles have a z average particle size of >100 nm to 2,000 nm as measured by dynamic light scattering.

Abstract: A composition includes at least one pH adjuster, at least one chelating agent, at least one anionic surfactant, at least one nitrogen containing heterocycle, at least one alkylamine compound, and an aqueous solvent, wherein the composition has a pH of from about 7 to about 14.

Abstract: The present disclosure relates to the use of whey protein as an anti-odour agent in a fabric, a textile finishing anti-odour method using whey proteins as an anti-odour agent, anti-odour compositions and anti-odour articles.

Abstract: Disclosed herein are compositions and methods for preventing, reducing, or removing biofilms and microbial growth from liquid solutions, as well as from surfaces, such as fabrics, textiles or hard surfaces.

Abstract: Disclosed herein are compositions and methods for preventing, reducing, or removing malodor and microbial growth from liquid solutions, as well as from surfaces, such as fabrics, textiles or hard surfaces.

Abstract: The present invention concerns a granule comprising Mn(II) oxalate, a protonated salt of a cyclic triamine, a polysaccharide absorbent and a coating agent. In another embodiment the invention concerns a granule comprising a polysaccharide absorbent, a protonated salt of a cyclic triamine and no or very small amounts of Mn. The invention also concerns methods of preparing said granules comprising Mn(II) oxalate, polysaccharide absorbent and such salts or comprising polysaccharide absorbent, such salts and no Mn compound and bleaching formulations comprising the granules and a peroxy compound or a precursor thereof. Granules comprising Mn(II) oxalate, polysaccharide absorbent and the salt or comprising polysaccharide absorbent, the salt and no Mn compound, and formulations comprising these are suitable for use in catalysing oxidation, for example as a component of a dishwasher bleaching composition. The invention further relates to methods of oxidising with the bleaching formulations described herein.

Abstract: A laundry scent additive having polyethylene glycol and perfume. The laundry scent additive enables consumers to control the amount of scent imparted to their laundry.

Abstract: A laundry scent additive having polyethylene glycol and perfume. The laundry scent additive enables consumers to control the amount of scent imparted to their laundry.

Abstract: A clothing aroma-enhancing bead composition and a method for preparing same are provided. The clothing aroma-enhancing bead composition includes the following raw materials in percentage by weight: 60-95% of sugar granules, 1.0-20% of liquid essence, and 0.5-20% of silica. The clothing aroma-enhancing bead composition takes the sugar granules as a core, and surfaces of the sugar granules are coated with the liquid essence and the silica. The clothing aroma-enhancing bead composition is attractive in appearance, good in solubility, and simple in production process.

Abstract: A cell culture system controller for controlling the environment of a cell culture system, the controller configured to receive intrauterine data and adjust an environmental parameter of a cell culture system environment over a period of time based on the intrauterine data.

Abstract: A bioreactor for producing hydrogen gas and metabolites and methods for making and using the same. The bioreactor comprises a main reactor chamber, a semipermeable membrane, a sleeve, microorganism, such as cyanobacteria, for producing hydrogen gas and metabolites, a power supply, a substrate medium, a heating member, a plurality of tubing members, a collection reservoir, a pressure-sealed connecter member, a metabolite purifying filter member, a light source, and an agitator. The bioreactor utilizes light, fermentation, and other metabolic processes for the production of metabolites, derived from various microorganisms contained within the bioreactor through respective metabolic pathways.

Abstract: A cell culture system or assembly, flask, plate and dish for growing, viewing and evaluating cells; and methods of use.

Abstract: Disclosed are various embodiments for growing, culturing, monitoring, and analyzing embryoid bodies, fused embryoid bodies, spheroids, organoids, or other multi-cellular bodies in a microwell structure formed in one or more wells of an assay and culturing microplate. Hydrogel deposited into a well of the microplate and supported by a support ledge and the bottom surface of the well is molded into a microwell structure using a mold insert tool. In some examples, channels can be formed in the bottom of the microwell structure to allow for an exchange of fluid between a primary well section and a secondary well section of the well. The bottom surface of the assay and culturing microplate is optically transparent and gas-permeable.

Abstract: A method for manufacturing a cell culture substrate in which cells are fixed via a hydrogel on a surface of a substrate includes forming a film of a first liquid on the surface of the substrate, and ejecting droplets of a second liquid onto the film.

Abstract: A method of bioprocessing includes the steps of providing a bioreactor vessel having a gas-permeable, liquid impermeable membrane, initiating a flow of gas, and passing the flow of gas across a bottom surface of the membrane to induce a turbulent interaction between the flow of gas and the membrane.

Abstract: A cover for a lagoon is provided. The cover includes an expandable membrane; a plurality of stretchable members coupled to the expandable membrane and configured to compress the expandable membrane; and a plurality of restraining members coupled to the expandable membrane and configured to limit expansion of the expandable membrane.

Abstract: A culture vessel has a culture space therein and may culture cells in the culture space. The culture vessel includes a main flow path extending within a plane, and a secondary flow path that is adjacent to the main flow path in a direction perpendicular to the plane, extends in a direction intersecting the main flow path when viewed from a direction perpendicular to the plane, and partially overlaps the main flow path. The secondary flow path has a groove that is open to and communicates with the main flow path in an area where the secondary flow path overlaps the main flow path, and the culture space is a space within the main flow path, the space being opposed to a contact surface where the secondary flow path is in contact with the main flow path in the area where the secondary flow path overlaps the main flow path.

Abstract: The present invention provides a culture device for biochemical testing. The culture device includes a first plate and a second plate, and the second plate is opposite to the first plate. The first plate and the second plate form an incubation cassette and a supply channel, and the incubation cassette is connected to the supply channel by a microstructure. The present invention can provide side views of multi-layered cellular samples, such as corneal tissue, and can be easily combined with other techniques for more comprehensive detection. In addition, applicable industries or products include: cell culture devices, in vitro clinical specimen culture, 3D cell culture, high-throughput drug screening, tumor invasion assessment, cell biology research, personalized precision medicine, etc.

Abstract: A system (100, 200, 400, 700) and method for growing biomass, wherein the system comprises at least one growing unit (110, 210, 410, 710) having a respective controllable environment and comprising a first area (120, 220, 420, 720) and a second area (130, 230, 430, 730). The system further comprises at least one plate-grid device (140, 240, 441, 442, 443, 500, 740) arranged within said at least one growing unit in turn comprising at least one plate (225, 325, 510) elevated from at least one grid (226, 326, 530, 631, 632, 633, 634) wherein the at least one plate and the at least one grid are independently movable from one another between the first area and the second area. Additionally, the system comprises a decontamination device (160, 260, 461, 462) arranged within the second area and configured to decontaminate, in the second area, one or more of the at least one plate and/or at least one grid of the at least one plate-grid device.

Abstract: The present invention provides rolled scaffold devices and cell culture systems that can provide a large surface-area-to-volume ratio for expanded cell culture. The rolled scaffolds minimize shear stress on cultured cells and support sufficient and uniform mass transfer rates of gases and nutrients. The rolled scaffolds can be connected to a media source via holders to support large-scale expansion and maintenance of cell cultures.

Abstract: A bioreactor includes a scaffold, a scaffold support, and a manifold. The scaffold is seeded with a plurality of cells. The scaffold has an extended state and a non-extended state. The scaffold support that selectively modifies a state of the scaffold from the non-extended state to the extended state. A manifold is configured to provide a medium to the scaffold. The state of the scaffold from the non-extended state to the extended state is modified at a rate tuned to maintain a cell density associated with the plurality of cells within a particular density range.

Abstract: The present disclosure relates to a system including a main exterior body. The main exterior body includes (i) a return section at a bottom of the main exterior body, (ii) a gas disengagement section at a top of the main exterior body, (iii) a riser section positioned between the return section and the gas disengagement section, and (iv) a downcomer section positioned between the gas disengagement section and the return section. The system also includes one or more first spargers each having a first end and a second end opposite the first end. Each of the one or more first spargers are positioned such that the first end is outside of the main exterior body and the second end is positioned in a lower portion of the riser section of the main exterior body. The one or more first spargers are configured to supply compressed gas to the riser section of the main exterior body. The system also includes one or more second spargers each having a first end and a second end opposite the first end.

Abstract: Provided is a bioreactor apparatus including: a liquid storage chamber for storing a culture medium; a pump for providing pressure to drive the flow of the culture medium; a plurality of culture chambers providing an accommodating space to accommodate the culture medium and a cell to be cultured; and a pipeline connecting the liquid storage chamber, the pump, and the culture chamber to form a closed loop. Also provided is a bioreactor system including the bioreactor apparatus of the present disclosure, the culture medium, and a cell. Further provided is a method for culturing a cell or an organoid by the bioreactor apparatus of the present disclosure. The bioreactor apparatus, bioreactor system, and method of the present disclosure can form a biomimetic circulatory system, which is beneficial for simulating and evaluating the complex microenvironment and physiological mechanism in the living body.

Abstract: A screen changing device is proposed. The screen changing device includes a first housing and a second housing configured to be rotated with respect to the first housing. The screen changing device can transit from a first configuration in which a first screen is aligned with a first connector and a second connector to a second configuration in which the first screen is not aligned with the first connector and the second connector and a second screen is aligned with the first connector and the second connector.

Abstract: Devices, systems, and methods for evaluating the viability of embryos are disclosed. In particular, devices, systems, and methods for measuring internal and external pH of an embryo, electrolytes, and oxidative stress markers for evaluating developmental potential of an embryo are provided. The methods disclosed herein should improve in vitro fertilization (IVF) outcomes by reducing inadvertent transfer of non-viable embryos.

Abstract: An automated cell culture device includes a main body and a clamping member. The main body encloses a receiving space and has a platform on a top face thereof. The platform has a sliding track extending along a sliding direction. Two ends of the platform along the sliding direction are defined as a first end and a second end respectively. The platform is adapted for support a culture bag lying thereon. The culture bag has a fluid inlet at an end thereof closer to the first end of the platform. The clamping member is slidably disposed on the sliding track and is adapted for clamping and pressing the culture bag to avoid fluid in the culture bag from flowing toward an end of the culture bag closer to the second end of the platform. The clamping member is slidable on the culture bag along the sliding direction.

Abstract: Provided is an isolated asporogenous strain of Clostridium tyrobutyricum bacterium comprising a single base pair mutation in a gene involved in the control of a sporulation process and methods of production thereof. Also provided is a feed ingredient comprising an isolated asporogenous strain of Clostridium tyrobutyricum bacterium, such as an asporogenous strain comprising a mutation in a gene involved in the control of a sporulation process.

Abstract: The present invention relates to a bacterial culture medium, to a method for producing the culture medium, and also to a method for culturing a bacterium, in particular an oxygen-sensitive bacterium. The culture medium of the present invention comprises, per liter of culture medium, the following components: from 20 to 40 g of potato peptones, from 2 to 5 g of anhydrous alkali metal acetate, from 3 to 7 g of a yeast extract, from 2 to 16 g of maltose monohydrate, from 0 to 1 g of a soluble L-cysteine salt, from 0.006 to 0.015 g of biotin, from 0.0005 to 0.0015 g of pantothenic acid or a salt thereof; and from 0.0015 to 0.0025 g of pyridoxal hydrochloride. The culture medium of the invention makes it possible to culture bacteria such as an intestinal anaerobic bacterium, F. prausnitzii, or an oxygen-sensitive bacterium or a strict anaerobic bacterium.

Abstract: The technology relates in part to a strain of Bacillus pumilus bacteria deposited under ATCC accession number PTA-126909 and compositions derived from the bacteria for a variety of uses, including cosmetic and commercial compositions. The bacteria may be processed in a variety of ways, such as disrupting the bacteria (e.g., physically disrupting and lysing bacteria by lyophilizing aqueous batches of the bacteria, microfluidization of batches of bacteria, and the like), with the cellular remains and/or cellular secretions from such processing being then formulated with additional components to make useful end products, such as topical sunblock, sunscreen compositions with SPF-boosting properties, or household paint. In various embodiments, the compositions derived from the bacteria may be applied to surfaces to provide protection from ultraviolet light, or embedded within compositions to provide UV stability.

Abstract: The present invention provides a supplement composition and method of preparation thereof for cell culture. The supplement composition comprises natural substances without using any animal based serum. The present invention provides slaughter free, effective and affordable supplement for growth of animal cells that eliminates or minimizes dependency on the fetal bovine serum.

Abstract: A serum-free and animal-component-free culture media for expansion of muscle satellite cells is disclosed. The disclosed media can be for use in cultured food applications. The disclosed media can include a baseline serum-free and animal component-free culture media and a recombinant version of albumin. The baseline media, in use, provides a baseline growth capability for expansion of the muscle satellite cells for use in cultured food applications. The disclosed media, in use, provides an improved growth capability for expansion of the muscle satellite cells. The improved growth capability is at least 50% greater than the baseline growth capability. Methods of making and using the disclosed media are also disclosed.

Abstract: An advanced manufactured transwell (AM-transwell), the AM-transwell comprises: a lower chamber; an upper chamber; a membrane disposed between the lower chamber and the upper chamber; and one or more legs. The one or more legs form at least a portion of the lower chamber. One or more of the lower chambers, the upper chamber, the membrane and the one or more legs is printed using a synthetic bioink. Methods for making and using the AM-transwell are also disclosed.

Abstract: An insect culture maintenance system includes a sequence of open-ended cylindrical tubes [500, 502, 504, 506] joined pairwise alternately at their tops and bottoms using multiple dual-cap connectors. Each dual-capped connector has a channel from an inside of a first cap to an inside of a second cap. In use, connectors that cap the bottoms of the tubes [508, 512] are filled with insect food media [518, 520], while connectors that cap the tops of the tubes [510] are open. As a result of this design, adults pass from one tube to the next through the top dual-cap connectors, while larvae pass from one tube to the next through the bottom dual-cap connectors, resulting in propagation of subsequent generations of insects through the sequence of tubes.

Abstract: A sperm sorting device suitable for selectively isolating a plurality of motile sperms from a semen specimen includes a base whose bottom wall and surrounding wall define a receiving space, and a sorter securely coupled to the base and including a mounting member and a sorting filter. The mounting member has a sleeve located in the receiving space and an injection portion located at the bottom end of the sleeve and having an injection hole. The sorting filter is fixed on the sleeve and, together with the injection portion and the sleeve, defines a sorting chamber with an open top end. The sorting filter, the bottom wall, and the surrounding wall define a specimen chamber for receiving the semen specimen. The injection hole brings the specimen chamber and the sorting chamber into communication vertically, so the semen specimen can be injected through the injection hole into the specimen chamber rapidly.

Abstract: In a method for efficiently inducing reprogramming of human cells into neuronal cells, a concentration of cAMP is increased or an expression of PKA and CREB is up-regulated or an expression of AMPK, ALK2, ALK3, P38, and JNK is inhibited by a single small molecule compound or gene knockout or gene overexpression. In the present disclosure, the induction small molecule compound is single and safe, and has a short induction time, high induction efficiency, definite induction sites and genes, and clear molecular regulation mechanism. The small molecule compound can be applied to the clinical treatment of human neurodegenerative diseases, providing a safer and more efficient treatment method for the neurodegenerative diseases. Since neuronal cells cannot divide and proliferate, the method induces fibroblasts and astrocytes that can divide and proliferate in vitro and in vivo, to continuously obtain a large number of induced neuronal cells in vitro and in vivo.

Abstract: The present disclosure provides iPSC-derived dopaminergic neurons comprised disease-associated mutations. Further provided herein are methods for using the iPSC-derived dopaminergic neurons for the study of neuroinflammation, such as to identify novel targets, biomarkers, and therapeutic agents for the diagnosis, prognosis, and treatment of neurodegenerative diseases. Further provided herein are assays for studying neuroinflammation using the present cell culture models.

Abstract: An apparatus for growing neuron cells comprises a micro-patterned microfluidic device enables fluidic isolation among microfluidic regions within the device. The device comprises first and second microfluidic regions each having an entry reservoir for accepting or extracting a first and second volume of fluid, respectively. The second volume of fluid is less than the first volume of fluid to create hydrostatic pressure. A barrier region couples the first microfluidic region with the second microfluidic region in a way that enables a biological specimen to simultaneously extend across the regions. The barrier region comprises a plurality of microgrooves having a width and height that enables the volumes of fluid to be fluidically isolated from the other via the hydrostatic pressure maintained via the at least one embedded microgroove.

Abstract: A cultured spherical body that is capable of easily performing quantitative analysis of a region containing brain neurons, useful as a supply source of neurons for transplantation, and can be used suitably for drug discovery screening for neurological diseases and compound evaluation systems is obtained. Provided are a cultured spherical body including a first cell layer containing neural stem cells and/or neural progenitor cells and a second cell layer containing brain neurons, wherein the first cell layer is present in the superficial portion of the cultured spherical body, and a method for producing the cultured spherical body.

Abstract: The present invention relates to genetically modified B cells and their uses thereof, for example, for the treatment of a variety of diseases and disorders, including cancer, heart disease, inflammatory disease, muscle wasting disease, neurological disease, and the like. In certain embodiments, the invention relates to an isolated modified B cell (“CAR-B cell”), capable of expressing a chimeric receptor (“CAR-B receptor”), wherein said chimeric receptor comprises (a) an extracellular domain; (b) a transmembrane domain; and (c) a cytoplasmic domain that comprises at least one signaling domain. In various embodiments, the invention comprises an isolated modified B cell, wherein said B cell is capable of expressing and secreting a payload, wherein the payload is not naturally expressed in a B cell or is expressed at higher levels than is naturally expressed in a B cell. In various embodiments, the payload is an antibody or fragment thereof.

Abstract: Disclosed are cells and cellular compositions useful for treatment of degenerative and/or autoimmune diseases derived from gene edited/gene modified pluripotent stem cells. In one embodiment pluripotent stem cell such as inducible pluripotent stem cells are gene modified to express tissue associated transcription factors such as pdx-1 if endodermal tissue is desired and cells are differentiated into regenerative-type cells such as along the mesenchymal lineage. In one embodiment the invention teaches transfection with IL-27 to induce expression of coinhibitory molecules for suppression of autoimmunity. In some embodiments the invention provides generation of iPSC derived MSC which can not stimulate inflammation due to gene-editing based removal of inflammatory associated transcription factors.

Abstract: A myogenin-expressing fibroblast-like cell (MEFLC) line and a construction method and a use thereof are provided. The MEFLC line was deposited in the Guangdong Microbial Culture Collection Center (GDMCC) on Apr. 23, 2022 with an accession number of GDMCC NO: 62409. The construction method includes: 1) constructing a pCW-MYOG-T2A-Puro lentivirus; 2) infecting a human induced pluripotent stem cell (iPSC) line with the lentivirus, inducing the expression of an MYOG gene, and screening out a positive monoclonal cell line; 3) subjecting the positive monoclonal cell line to expanded cultivation, during which the expression of the MYOG gene is continuously induced; and 4) changing cultivation conditions, continuously inducing the expression of the MYOG gene, and screening out positive monoclonal cell lines to ensure the purity of MYOG-positive cells until a cell morphology changes significantly into fibroblastoid cells to obtain the MEFLC line.