Abstract: A degassing method for a multiple catheter fluid management system includes injecting a first fluid at a low pressure from a first fluid source into a first fluid source connection of a hemostasis valve, closing a first valve at the first fluid source connection, applying vacuum to a sink connection of the hemostasis valve to remove residual first fluid into a sink connected to the sink connection, closing a sink valve at the sink connection, and injecting a second fluid from a second fluid source into a second fluid source connection of the hemostasis valve.

Abstract: A nebulizer comprising a power supply system of the present invention performs wireless power supply from a power transmission-side circuit to a power reception-side circuit. The power transmission-side circuit transmits a power to the power reception-side circuit at a certain oscillation frequency through a power transmission coil. In the power reception-side circuit, a power reception coil and a load configure a power reception-side resonance circuit to determine a resonance frequency of the power reception-side resonance circuit. When the resonance frequency of the power reception-side resonance circuit changes due to a change in an impedance of a load during power supply, a control unit controls an oscillation frequency to maintain a power transmission efficiency from the power transmission-side circuit to the power reception-side circuit.

Abstract: An inhaler article has an inhaler body comprising a tubular side wall defining an interior and a longitudinal center axis, the interior forming a receptacle for housing an inhalable powder; a mouthpiece element extending along the longitudinal center axis from a distal end to a proximal end, the distal end of the mouthpiece element being received in the interior of the inhaler body. The mouthpiece element includes a tube extending coaxially with the inhaler body and comprising an interior surface having a first diameter; a blocker disposed at the distal end of the mouthpiece element, coaxial with the tube and having a second diameter that is greater than the first diameter; and a collector surface comprising a ring that is coaxial with and disposed proximal to the blocker, the ring defining an inner diameter and an outer diameter.

Abstract: The present disclosure describes a capsule inhaler. The capsule inhaler includes a main body including an inner cavity, a mouth section coupled to or integral with the main body and in fluid communication with the inner cavity, an actuator coupled to the main body, at least four longitudinally spaced apart nozzles residing within the main body positioned and configured to direct airflow into the inner cavity, and a cover coupled to the main body. The inner cavity is sized and configured to receive a capsule containing a dry powder formulation. One or more of the inner cavity, elongate member, and cover each are configured to engage with the capsule when inserted into the inner cavity and assist in separating the capsule to release the dry powder formulation into the inner cavity of the inhaler for inhalation by a subject.

Abstract: An inhaler article is provided, including: a cavity; a capsule located in the cavity, the capsule containing dry powder; and a hollow tubular element disposed downstream of the capsule, the hollow tubular element including: a peripheral portion defining a hollow inner region of the hollow tubular element, and a support element formed from a sheet and extending from a first point at the peripheral portion across the hollow inner region to a second point at the peripheral portion. An inhaler system, including the inhaler article and a holder configured to receive the inhaler article, is also provided.

Abstract: A dry powder inhaler includes an inhalation channel connected to a mouthpiece, a container for storing a powdered medicament, a de-agglomerator with a vortex chamber located at an end of the inhalation channel, a metering device including a shuttle having a dosing recess. The shuttle is movable between a filling position, in which the dosing recess is in alignment with an opening of the container, and an inhalation position, in which the dosing recess is in alignment with the vortex chamber. The opening of the container is elongated along a major axis and the dosing recess is elongated along a main axis and, when the shuttle is in the filling position, an edge of the opening of the container encloses the dosing recess.

Abstract: A head-mounted respiratory assistance apparatus configured to provide a respiratory gases stream to a user. The head-mounted respiratory assistance has a main body securable to the head of a user and a blower unit that is operable to generate a pressurised gases stream from a supply of gases from the surrounding atmosphere. A patient interface is provided on the main body that has a gases inlet which is fluidly connected to the blower unit and which is configured to deliver the pressurised gases to the user's nose and/or mouth.

Abstract: The present disclosure relates to a method for determining movement of a user while using a respiratory therapy system is disclosed. Acoustic data associated with the user of the respiratory therapy system is received. The received acoustic data is analyzed. Based at least in part on the analyzed acoustic data, a movement event associated with the user is determined.

Abstract: An oral medical apparatus includes a flexible tube with a first portion adjacent a proximal end of the tube and a second portion adjacent to the first portion. A support is located within the upper portion to prevent compression or collapse of the upper portion of the tube. The oral medical apparatus can accommodate a rigid connector that may be directly coupled to an anesthesia breathing circuit or a medical breathing device.

Abstract: A tracheostomy tube flange (13) of a liquid silicone material has openings (14) towards opposite ends for receiving ends of a neck strap. The openings (14) are reinforced with overmoulded inserts (137, 138) of a heat cured silicone material having a similar hardness to that of the flange material. The inserts (137, 138) have an outwardly-projecting ledge (144) between their ends.

Abstract: A patient interface comprising a chassis portion at least partially forming a plenum chamber; a seal-forming structure; a vent to allow a continuous flow of gases exhaled by the patient from an interior of the plenum chamber to ambient, said vent being sized and shaped to maintain the therapeutic pressure in the plenum chamber in use; wherein the chassis portion comprises a membrane portion formed at least partially from a textile material and the seal-forming structure is supported on the membrane portion, and the membrane portion is constructed and arranged to be flexible to allow for relative movement between the seal-forming structure and the chassis portion in use.

Abstract: A mask 100 configured to substantially surround an opening of a patient's airway. The mask has a mask body 101 comprising a filter 103 configured to filter a fluid from a patient facing side of the mask to a non-patient facing side 105 of the mask, wherein the non-patient facing side faces an ambient environment AE. The mask has an interfacing feature 121 configured to, in use, interface with a patient interface 10100, 10100? provided on the patient 10020.

Abstract: This invention relates to a headgear comprising a semi-rigid frame engageable with the head of a user and a releasable connection system for releasable connection with a user interface, wherein the frame extends generally about a rear region of a user's head, generally about an upper region of a user's head, and generally about an ear or both ears of a user.

Abstract: A mask system includes a frame defining a breathing chamber, a cushion provided to the frame and adapted to form a seal with the patient's face, and a shroud provided to the frame and adapted to attach headgear. The shroud includes a retaining mechanism structured to connect the shroud to the frame. The retaining mechanism includes both a taper lock arrangement and a retaining clip arrangement.

Abstract: A breathing gas delivery pipe, a nasal catheter, and a ventilation therapy device. The breathing gas delivery pipe is used for delivering gas to a patient interface, and comprises a gas delivery pipe body (1); and the gas delivery pipe body (1) comprises a gas delivery channel (2) and a heat preservation structure used for preserving heat of the gas delivered in the gas delivery channel (2). In this way, the heat preservation structure preserves the heat of the gas delivery pipe body (1), so that the temperature drop in the gas delivery channel (2) can be effectively slowed down or avoided, thereby temperature drop of the gas delivered in the gas delivery channel (2) is further slowed down or avoided, and the generation of condensed water in the gas delivery channel (2) is avoided.

Abstract: The gases temperature supplied to a patient when the patient is undergoing treatment such as oxygen therapy or positive pressure treatment for conditions such as Obstructive Sleep Apnea (OSA) or Chronic Obstructive Pulmonary Disease (COPD) is often measured for safety and to enable controlling of the humidity delivered to the patient. The invention disclosed is related to measurement of properties, particularly temperature (thermistor), of gases flowing through a heated tube, supplying gases to a patient, which utilises the heating wire within the tube.

Abstract: Some embodiments provide a breathing assistance apparatus comprising a conduit for conveying gases therein, the conduit comprising circuitry. The circuitry may comprise at least one heater wire part to heat gases in the conduit, in use, and at least one sensor wire part comprising at least one sensor for monitoring a parameter of the gases in the conduit. There is also provided a controller to control provision of AC power or AC voltage to the heater wire part; and control selective reading of the sensor. The controller may be configured to read the sensor at or about a particular portion of the AC power waveform provided to the heater wire part.

Abstract: A system for thermal regulation of a nebulizer is provided that is structured to deliver a chilled mist to the snout, muzzle, beak, or trunk of an animal. The system includes a container to house a nebulizer and a thermal material together and a mask to deliver the chilled mist to an animal. The thermal material acts to chill a liquid located inside the nebulizer in order to deliver a chilled mist to the animal for therapeutic purposes, such as initiating therapeutic hypothermia, or treating various respiratory illnesses such as croup, laryngobronchitis, and smoke inhalation.

Abstract: A positive airway pressure (PAP) device for supplying a flow of breathable gas to a patient includes a flow generator configured to pressurize a flow of breathable gas and a humidifier configured to receive and humidify the pressurized flow of breathable gas from the flow generator. The PAP device also includes a power source. The flow generator, humidifier and power source are positioned so that heat generated by at least one of the flow generator and the power source is conveyed to water in the humidifier.

Abstract: Provided is a system for operating a ventilator. The system includes a motorized proportional valve actuator including a stepper motor and an actuator. The actuator is connected to the stepper motor and configured to output pressurized air by controlling a pressure on a valve diaphragm. A conduit provides for fluid communication of the pressurized air to a breathing apparatus. A sensor arrangement is in fluid communication with the conduit between the at least one motorized proportional valve actuator and the breathing apparatus. The sensor arrangement includes: (i) an intake manifold configured to output a restricted flow of air from the pressurized air transported in the conduit, and (ii) a sensor device in fluid communication with an outlet of the intake manifold, the sensor device configured to measure an air pressure of the conduit based on the restricted flow of air.

Abstract: Various aspects include wearable devices and related approaches for stimulating nerves proximate a user's ear, e.g., providing one or more health benefits. In some particular aspects, a wearable device for providing vibrotactile stimulus to at least one nerve proximate an ear of a user includes: an earpiece having a vibration device for application of vibrotactile stimulus proximate at least one of a concha region or an ear canal of the user; and a controller connected with the vibration device, the controller configured to actuate the vibration device according to a modulated pattern to stimulate at least one nerve proximate the ear of the user, where the modulated pattern is characterized by: a peak drive level sufficient to stimulate nerve endings of at least one nerve proximate the ear of the user; and a carrier frequency of approximately 50 Hertz (Hz) to approximately 500 Hz.

Abstract: A hot-cold tactile presentation device includes a plurality of thermoelectric elements which are arranged in a matrix by placing the thermoelectric elements side by side along x and y directions respectively, a plurality of row_heat lines each extending in the x direction, and a plurality of column lines each extending in the y direction. The plurality of row_heat lines are each connected to one end of each of the plurality of thermoelectric elements that align in the x direction, and the plurality of column lines are each connected to the other end of each of the plurality of thermoelectric elements that align in the y direction.

Abstract: A bedding system includes: a bedding; an auxiliary mechanism that is incorporated in the bedding and is to assist change of a body position of the user, the auxiliary mechanism including a plurality of column members that are long along a thickness-wise direction of the bedding, are individually movable along the thickness-wise direction, and are arranged to be parallel to each other; and a first control unit that controls movement of each of the column members.

Abstract: A one-piece catheter (30) and manufacturing method therefor are disclosed. The catheter (30) includes a catheter tube (33) and an adapter (31). The catheter catheter tube (33) includes a tip (331) at one end and an end portion (332) at another other end. The adapter (31) can be configured for receiving a septum (402). The adapter (31) includes a narrow opening. The end portion (332) of the catheter tube (33) is connected to the adapter (31) at the narrow opening for fluid communication between the catheter tube (33) and the adapter (31). The catheter tube (33) and adapter (31) are formed as a one-piece element that is preferably injection molded in a single-shot process. Additional elements, such as one or more retention tabs (313) for attaching to a base can be formed on the catheter (30). The one-piece catheter (30) can be made by a single-shot injection molding process. Additional structures, such as a base can be attached to the catheter (30) by a second-shot injection molding process.

Abstract: A semiconductor light-emitting device includes a bonding substrate, a multi-layered metal unit, and a semiconductor lighting unit. The bonding substrate includes an upper surface and a lower surface opposite to the upper surface. The multi-layered metal unit is disposed on the upper surface of the bonding substrate such that an exposed region of the upper surface of the bonding substrate is exposed from the multi-layered metal unit. The semiconductor lighting unit is disposed on the multi-layered metal unit opposite to the bonding substrate. A method for manufacturing the semiconductor light-emitting device is also disclosed.

Abstract: Described is a catheter arrangement in which a sealed container of wetting agent is provided in a housing cap. The sealed container is pierced with a piercing member such that the wetting agent is directed towards the catheter. The wetting agent may bypass a handling surface of the catheter whilst being directed to the catheter tube.

Abstract: Described is a catheter arrangement in which a sealed container of wetting agent is provided in a housing cap. The sealed container is pierced with a piercing member such that the wetting agent is directed towards the catheter. The wetting agent may bypass a handling surface of the catheter whilst being directed to the catheter tube.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a proximal member having a proximal end, a distal end, and a proximal diameter. The guide extension catheter may additionally include a collar member attached to an extension portion of the proximal member, where the extension portion may be located at the distal end of the proximal member. The extension portion may allow a delivery device to be inserted through the guide extension catheter to extend along a surface of the extension portion and align with a lumen of a distal sheath of the guide extension catheter.

Abstract: Described are methods, systems, and devices for facilitation of intraluminal medical procedures within the neurovasculature including catheters and catheter advancement elements.

Abstract: The objectives for the designs presented herein can be for a variably flexible and kink-resistant catheter for vascular applications. The designs benefit from good compressive and tensile stiffness. A braided wire support structure can be disposed around an inner liner and an outer layer having a plurality of outer jackets of variable durometer. A metallic reinforcing layer can be cut from a hypotube and be used as the primary structure for catheter stiffness, reducing the reliance on and number of jackets to transition stiffness changes along the length of the catheter. The metallic reinforcing layer can have one or more ribbon cut segments and one or more axial hole patterns laser cut into the hypotube to progressively evolve the stiffness from proximally regions with more column stiffness and distal regions with greater lateral flexibility. The polymer jackets can be reflowed to bond the structure together.

Abstract: The trapping balloon catheter includes a catheter shaft formed to predetermined total length L from a rear end connected to a hub to a tip. A balloon is provided in a tip region of the catheter shaft and urges and fixes a guide wire to an inner peripheral surface of a guiding catheter by being expanded in a lumen of the guiding catheter. A stopper is provided on an outer peripheral surface of the catheter shaft and is capable of adjusting a length (effective length) in which the trapping balloon catheter is inserted into the lumen of the guiding catheter, by changing a locking position.

Abstract: A pain management system with a neuromodulation subsystem includes a medication dispenser located external to a patient. A subcutaneous port is placed internally to the patient and receives a quantity of medication. The port can be filled from a syringe or medication dispensing system. An echogenic catheter can be placed in proximity to a patient's nerve or nerve center using a point-of-care ultrasound imaging system. A pain management method includes the steps of placing a subcutaneous port using ultrasound imaging for guidance and administering pharmacologic agents via a catheter connected to the port. Neuromodulation can be applied as an alternative to or in conjunction with medication. Alternative embodiment catheter systems include echogenic tips, a stylet, and multiple internal coil sections to facilitate accurate placement. Alternative embodiment pain management methods include the steps of utilizing such features for optimizing patient outcomes.

Abstract: A probe (24) is provided for use with an elongate medical instrument (20). The probe (24) is configured to be advanced through vasculature of a body of a subject, and includes a distal longitudinal probe-portion (26) and one or more loops (30). The one or more loops (30) are disposed along the distal longitudinal probe-portion (26) and are configured to be looped around a distal longitudinal medical-instrument-portion (28) of the elongate medical instrument (20) when the distal longitudinal probe-portion (26) is positioned at least partially alongside a distal longitudinal medical-instrument-portion (28) within the body, thereby mechanically coupling the distal longitudinal probe-portion (26) to the distal longitudinal medical-instrument-portion (28) within the body. The probe (24) is configured to bend the elongate medical instrument (20) within the body when the distal longitudinal probe-portion (26) is mechanically coupled to the distal longitudinal medical-instrument-portion (28).

Abstract: Medical devices, such as catheters, may include sensors for detecting or measuring desired parameters. In a related method, a flexible, elongate member is inserted into a vein of a patient. The distal end of the flexible, elongate member is positioned near a cavoatrial junction of the patient (e.g., within the superior vena cava). A fluid is passed through a lumen of the flexible, elongate member and through an exit port of the flexible, elongate member. A temperature of the fluid may be determined using a first sensor associated with the flexible, elongate member, and then amount of time that it takes for a second sensor to record a temperature that correlates with the determined temperature of the fluid is measured. A flow characteristic may then be determined based on a known distance between the first sensor and the second sensor and the measured time period.

Abstract: There is provided a fixation device to secure a catheter tube. The fixation device comprises a body with a proximal surface and a distal surface, a first opening in the proximal surface, a second opening in the distal surface, and a sidewall that connects the first opening and the second opening to form a through-hole. The body is configured to receive a first portion of the catheter tube. The fixation device further comprises a retainer configured to retain the first portion of the catheter tube in the channel. The body is configured such that the catheter tube extends in use from the body through the through-hole to an exit point at which a second portion of the catheter tube exits the patient's skin. The body is configured such that the sidewall is in use spaced from the exit point to create a window to a region of the patient's skin.

Abstract: The guide wire includes a core shaft, a coil body with a wire helically wound around the outer periphery of the core shaft, and a coating layer provided on the outer periphery of the coil body. The coating layer has a peak portion protruding in the outer peripheral direction of the guide wire in a swollen state. On a cross-section including a central axis of the coil body, an apex of the peak portion is present at a position on a proximal end side of a first virtual straight line that extends through a central point of a first transverse section of the wire and is perpendicular to the central axis and at a position on a distal end side of a second virtual straight line that extends through a central point of second transverse section of the wire and is perpendicular to the central axis.

Abstract: A portable hand-held medical device includes a body having a gun-type formation that includes a barrel. A guide wire device is housed in the body and is configured to advance and retract through the barrel. The guide wire device carries a bundled arrangement including a video system, an illumination system to support the video system, a fluid irrigation line, and a guide wire mechanism. The bundled arrangement is packaged as a unit in an insertion tube. The tip section of the insertion tube incorporates a camera, a light source, and a fluid irrigation port. A catheter is disposed at the end of the barrel, so that during operation the guide wire device passes through the catheter lumen. The combination guide wire device and catheter enter the urinary tract and perform a bladder evacuation process.

Abstract: An apparatus, assembly, and method for controlling release of a drug from a drug-eluting balloon during delivery of a drug-eluting balloon to a situs within a body. More particularly, the present invention relates to a diametrically expandable sleeve having a first non-diametrically unexpanded state in which drug retained on or in a drug-eluting balloon is protected from release by a sleeve and a second diametrically expanded state in which drug retained on or in the drug-eluting balloon is exposed for focal release in the body by diametric expansion of the sleeve, exposing openings in the sleeve during diametric expansion and closing the openings in the sleeve when the sleeve is in its diametrically unexpanded state.

Abstract: Apparatus and methods for treatment of bleeding and/or microbial infection of the genitourinary tract including a catheter and an insertable and removable medicament-delivery sheath for introducing a hemostatic and/or anti-microbial substance or the like. Some embodiments further include a light-delivery sheath and/or light-delivery-and-imaging sheath having a light-propagation channel, and a source of anti-microbial and/or imaging light in one or more wavelength bands, for example UVC light and/or light in the visible violet, blue or green wavelength ranges. Some embodiments include a display for captured images, and/or a motorized sheath-movement device configured to move one or more light-output ports.

Abstract: The present invention discloses a device for the collection and scavenging of biological samples, and drug delivery for upper and lower respiratory tracts and hollow organs. The device comprises a distal balloon assembly (101) comprising distal carrier disc (101a) and a distal balloon (102), a proximal balloon catheter assembly (103) comprising proximal carrier disc (103a) and a proximal balloon (104), an inflation tube (108), a double lumen catheter (105) with an outer tube (105a) and an inner tube (105b), an agitator (106) working by methods such as ultrasonication, vibration, rotation, to-and-fro movements, pulsations etc, a flexible rod (107) to mount the agitator (106). Thus, the invention provides the device or a catheter with balloons to isolate pathogens or viruses from nasal cavity, nasopharynx, or relevant segment of hollow organs, with or without the use of water or similar liquids.

Abstract: Disclosed are a fluid drainage devices and methods of use for drainage of edematous tissues of a patient. The devices include an inlet catheter comprising a plurality of lumens configured to receive fluid from the edematous tissues, wherein the plurality of lumens run axially parallel in the inlet catheter; an outlet catheter configured to be anchored at a sink; an implantable pump coupled to the inlet catheter and the outlet catheter, the pump having a rotating portion including a permanent magnet, the rotating portion configured to rotate in response to a magnetic force external to the patient to move fluid from the inlet of the inlet catheter to the second end of the outlet catheter; and an external controller configured to transcutaneously couple to the permanent magnet of the rotating portion to apply the magnetic force to the implantable pump.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: The present invention teaches a cylindrical tattoo tube which includes an ink reservoir located on one side of the cylinder. A plunger may be included in the ink reservoir to control the amount of ink being dispensed. A user may manually actuate the plunger while tattooing, thereby eliminating the need constantly dip during the tattooing procedure.

Abstract: The present disclosure includes system, methods, and kits relating to creating a second structure with a plurality of first structures at a target site inside or adjacent to a host object. The methods include the step of generating a field that non-invasively penetrates into the host object. The methods further include the step of positioning a first portion of the plurality of first structures at the target site using a force corresponding to the field. Additionally, the methods include the step of linking the first portion of the plurality of first structures with one another and/or the host object at the target site to form the second structure.

Abstract: A fluid flow disconnect sensor and alarm system includes first and second sensor units configured to be removably coupled to a first and second portions of a fluid connector assembly, respectively. The first sensor unit comprises a sensor configured to sense when the second sensor unit is within a threshold distance of the first sensor unit, and comprises a transmitter configured to transmit, to a device remote from the first and second sensor units, an indication regarding whether the first and second portions of the fluid connector assembly are coupled together responsive to the sensing. A computing device receiving the indication determines when the first and second portions of the fluid connector assembly are coupled together, and when the assembly becomes disconnected, and may generate an alarm when the first and second portions become disconnected.

Abstract: A coupling device that is removably couplable with a mating connector is disclosed where the coupling device can include a housing and another structure that is movable relative to the housing such as an inner body or a cuff, and in a first configuration, the coupling device resists separation between the coupling device and a mating connector, in a second configuration, the resistance to separation between the mating connector and the coupling device is reduced relative to the first configuration such that the coupling device can permit separation between the coupling device and the mating connector when any of the inner body or the cuff is moved, biased, and/or flexed, and where the coupling device can be re-coupled with a mating connector after separation between the coupling device and the mating connector.

Abstract: A hermetically sealed thermoplastic container or ampoule having a hollow body portion, a neck portion, unitary with the body portion and terminating in a circumferential flat sealing surface that defines an access aperture, and a removable cap. The neck portion is provided with an external thread and defines an access passageway to the hollow body portion. Part of the neck portion is configured as a tapered female connector adapted to receive a tapered male connector when the access passageway is open.

Abstract: A valve and system for controlled delivery of medical fluids to a patient from two or more syringes can be manipulated by a one hand of an operator. The valve includes syringe ports for connecting two or more syringes to the valve and a stop cock that is operable by a handle to selectively connect one syringe at a time to a needle or catheter for delivery of medical fluid to the patient. The valve is configured such that an operator can use his or her the thumb for either operation of the syringe plungers for injection of the liquid contained in the syringe or alternatively for the operation of the valve handle to select which syringe will be operational.

Abstract: Some embodiments of percutaneous ventricular assist devices have a two-part design that includes a housing component and a separately deployable rotatable inner catheter component. The housing component can include an expandable pump housing. The inner catheter can include an expandable pump impeller and an associated flexible drive shaft. The drive shaft can be coupled to a motor located external to the patient. The motor can rotate the drive shaft to spin the pump impeller inside of the pump housing, causing blood to be pumped within the patient. In some embodiments, the pump impeller is inflatable or self-expandable. The two-part percutaneous ventricular assist devices with inflatable or self-expandable pump impellers are designed to have very small delivery profiles. Accordingly, various deployment modalities, including radial artery deployment, are practicable using the two-part percutaneous ventricular assist devices described herein.