Abstract: Disclosed is a method for generating an ABP signal, with at least one heart-motion-induced signal being detected. The at least one detected heart-motion-induced signal is transformed into at least one ABP signal. The transformation is carried out using a model that was generated by machine learning. The heart-motion-induced signal constitutes the input value, and the ABP signal constitutes the output value of the transformation.

Abstract: An apparatus for non-invasively estimating bio-information and a method of determining whether a bio-signal is normal by the apparatus for estimating bio-information are provided. The apparatus for estimating bio-information according to an embodiment of the disclosure includes: a photoplethysmogram (PPG) sensor configured to measure a PPG signal from an object; and a processor configured to extract a plurality of pairs of local maximum points and local minimum points from a second derivative signal of the PPG signal, to select at least one reference pair from among the extracted plurality of pairs, and to determine whether the PPG signal is normal based on the selected at least one reference pair.

Abstract: Provided herein are devices, systems, and methods for assessing, treating, and for developing new treatments for pulmonary arterial hypertension (PAH) using pulmonary artery pressure (PAP) values and/or cardiac output (CO) estimates.

Abstract: A sensor implant system comprises a shunt body comprising a central flow portion configured for placement at least partially within an opening of a tissue wall and the sensor implant system comprises a sensor implant device comprising a sensor body. The sensor implant device is configured for placement within the opening of the tissue wall and between the central flow portion of the shunt body and an inner wall of the opening of the tissue wall.

Abstract: The present disclosure provides to identify regions of a cardiac cycle based on pressure measured intravenously during a procedure and to derive a fractional flow reserve from the measured pressure during the identified regions. Further the disclosure provides to derive a trend line of the derived fractional flow reserve while the patient in undergoing a procedure, such as a pre-percutaneous coronary intervention.

Abstract: The present invention includes a pressing cuff for compressing a measurement target site. A sensing cuff containing a pressure transmission fluid is provided on an inner circumferential side of the pressing cuff. A pressure at a rising start point and a pressure at a peak point indicated by a pressure pulse wave for each beat are obtained by subtracting a direct current component of data representing a pressure of the pressing cuff from data representing a pressure of the sensing cuff in the process of depressurization. A first time point at which the pressure at the peak point for each beat transitions between a zero level and a positive value is obtained. A second time point at which the pressure at the rising start point for each beat transitions between the zero level and the positive value is obtained.

Abstract: Provided is a blood pressure measuring device. The blood pressure measuring device is configured to be worn around a wrist of an examinee, and includes: a first strap configured to be wound on a part of the wrist adjacent to an ulnar artery; a second strap connected to the first strap to be worn around the wrist, configured to be worn on a part of the wrist adjacent to a radial artery, and including an air pocket into and from which air selectively flows; and a main body provided on the first strap or the second strap and including a measurement unit configured to measure a pressure of the air pocket and a controller configured to calculate a blood pressure of a user based on the pressure of the air pocket measured by the measurement unit.

Abstract: A drive circuit for measuring blood pressure that generates a first drive signal for driving a valve for opening and closing a flow path connected to a blood pressure measurement cuff and a second drive signal for driving a pump for supplying a fluid to the cuff. The first drive signal and the second drive signal are generated from a common power supply voltage supplied from a power source circuit. Envelopes thereof have a common shape changing at a same timing.

Abstract: The present disclosure relates to a technique for estimating the inter-beat interval (IBI) of a ballistocardiograph (BCG) signal measured using a non-contact sensor, filtering and correcting inaccurate information in the inter-beat interval estimated through clustering, and outputting a heart rate measurement result based on the filtered and corrected inter-beat interval.

Abstract: An apparatus can include an antenna, transmitter circuitry coupled to the antenna, and processing circuitry coupled to the transmitter circuitry. The processing circuitry can measure a first reflection coefficient of the antenna in free space and a second reflection coefficient of the antenna when the antenna is proximate biological tissues. The processing circuitry can determine a contextual property of the biological tissues based on a comparison between the first coefficient and the reflection coefficient proximate biological tissues.

Abstract: A meridian impedance measuring device that can be worn on a wrist or an ankle is provided, including: one or more stretchable parts, constituting part of a watchband, to allow a length of the watchband to be stretched by 1.3 times or more than 1.3 times of an original length; an electrode holding part, including six or more individual pieces that are connected with the stretchable parts, wherein, each piece may hold a pair of electrodes; six or more pairs of electrodes, wherein, one of each pair of the electrodes is a measuring electrode, and the other is a reference electrode, and the six or more pairs of electrodes are arranged on the electrode holding part around the wrist or the ankle; an integrated circuit part for measuring skin impedance; and a case, to house the integrated circuit part.

Abstract: A method for checking a position and/or an orientation of a catheter tip of a catheter, in particular a central venous catheter, in a patient's body, a medical system set up for carrying out such a method, and a use of such a method during a catheterization.

Abstract: Detection devices for detecting one or more target analytes such as volatile organic compounds (VOCs) may include a base and a sensor module coupleable to the base and including at least one electrochemical sensor, where the electrochemical sensor includes an electrode and an ionic liquid (e.g., room temperature ionic liquid) that is arranged on the electrode and specific to a target analyte. In some variations, at least one cavity specific to the target analyte is formed within the ionic liquid in response to the electrochemical sensor receiving an input signal.

Abstract: Compositions and methods for the diagnosis and treatment of Covid 19 are disclosed.

Abstract: Measuring device (1) for analyzing a respiratory gas flow, comprising at least one measuring unit (4) and a cuvette (5), the cuvette (5) being releasably connected to the measuring unit (4) and being adapted and configured so that a respiratory gas flows through said cuvette, the measuring unit (4) having at least two sensor units (41, 42), at least one sensor unit (41) being configured to determine a respiratory gas flow and at least one sensor unit (42) being configured to determine a CO2 concentration in a respiratory gas, and the cuvette (5) comprising at least two sensor connections (51, 52) for connecting the sensor units (41, 42) for determining at least one respiratory gas flow and at least one CO2 concentration of a respiratory gas.

Abstract: The embodiments disclose a method including making electrodes using an electrically conductive material for impedimetric detection of analytical targets in an electrochemical sensing platform device, collecting patient samples in a solution compartment of the electrochemical sensing platform device, binding primers and aptamers to electrodes for functionalizing electrodes for detecting and binding targeted viruses and bacterial pathogens, incubating oral fluid samples in the solution compartment using a heater, measuring electrode impedance changes, recording measured electrode impedance changes in a memory device, and integrating wireless technologies into the electrochemical sensing platform device configured for transmitting recorded measured data.

Abstract: A device for determining the location of a pelvis of a person, comprising at least one first pressure transmission element designed for absorbing a sitting pressure/contact pressure exerted by the coccyx/pubic bone of the person and at least one second pressure transmission element designed for absorbing a contact pressure exerted by the sacrum of the person and an evaluation unit, the evaluation unit being designed for performing the following steps: receiving measuring signals from the pressure transmission elements and evaluating them; determining a first characteristic pressure distribution in which, during a rotation of the person's pelvis around his or her horizontal axis, the first pressure transmission element is charged with a sitting pressure of the coccyx or the first pressure transmission element is charged with at least part of the contact pressure of the pubic bone; and determining a second characteristic pressure distribution in which the sitting pressure of the coccyx exerted on the first pres

Abstract: A method of determining the place and location of a human pelvis, including detecting sitting pressures/contact pressures exerted on the seat, the lounger or the support by the ischial tuberosities and the coccyx of the sitting person or by the iliac crests and the pubic bone of the lying person by a surface sensor; determining, by a computer unit, a first position on the surface sensor where a first peak sitting pressure/peak contact pressure is reached; determining a second position on the surface sensor where a second peak sitting pressure/peak contact pressure is reached; determining a distance between the first position and the second position; determining a third position on the surface sensor where a third peak sitting pressure/peak contact pressure is reached, the position being between the first position and the second position; and limiting an area of the surface sensor which detects sitting and contact pressures.

Abstract: An acoustic wave measurement apparatus includes: an image display unit that displays an acoustic wave image; a measurement target designation receiving unit that receives designation of a measurement target; a position designation receiving unit that receives designation of a position of a measurement target on the acoustic wave image displayed on the image display unit; a measurement method information receiving unit that receives measurement method information indicating a measurement method; a detection measurement algorithm setting unit that sets a detection measurement algorithm based on the measurement target received by the measurement target designation receiving unit and the measurement method information received by the measurement method information receiving unit; and a measurement unit that detects the measurement target based on the received position and the detection measurement algorithm and performs measurement for the detected measurement target.

Abstract: A calibration fixture provides a repeatably accurate tool for measuring offset angles between measurement axes for inertial measurement units (IMUs) used in motion capture. The measured offset angles may be used to correct angles measured by the IMUs to create a biomechanical skeleton that accurately represents movements of a motion capture subject. The disclosed embodiments are applied segments of a biomechanical skeleton providing a mathematical model of a human arm and hand.

Abstract: A system for diagnosing a foot condition by scanning the foot includes a shape data module for detecting various shapes of foots and storing shape data; a condition data module for detecting the foot condition or a foot related condition and storing the condition data; a foot standard database for generating a standard data of the food based on the data stored in the shape data module and a condition data module and storing the generated standard data; a shape scanning data module for generating a 3D shape data related to the foot shape by scanning the foot in 3D way; a condition measuring data module for measuring a foot condition by scanning the foot and generating a foot condition data; and a foot diagnosing data module for generating a foot data based on the data generated by the shape scanning data module and the condition measuring data module.

Abstract: A ballistocardiogram sensor according to an embodiment of the inventive concept includes a lower substrate including a support part, a plurality of connection parts, and a vertical movement part, a lower electrode on the lower substrate, a piezoelectric sensing layer on the lower electrode, and an upper electrode on the piezoelectric sensing layer. The vertical movement part is spaced apart from the support part with the connection parts therebetween. The connection parts connect the vertical movement part and the support part. The piezoelectric sensing layer vertically overlaps the vertical movement part. The connection parts may have a serpentine shape.

Abstract: In order to estimate the type of footwear worn by a pedestrian, an estimation device and the like according to the present invention are provided with: an extraction unit which acquires sensor data from a sensor installed on the footwear, and uses the sensor data to extract a walking feature quantity characteristic of walking in footwear; and an estimation unit which estimates the type of footwear on the basis of the walking feature quantity extracted by the extraction unit.

Abstract: In order to estimate the type of footwear worn by a pedestrian, an estimation device and the like according to the present invention are provided with: an extraction unit which acquires sensor data from a sensor installed on the footwear, and uses the sensor data to extract a walking feature quantity characteristic of walking in footwear; and an estimation unit which estimates the type of footwear on the basis of the walking feature quantity extracted by the extraction unit.

Abstract: In order to estimate the type of footwear worn by a pedestrian, an estimation device and the like according to the present invention are provided with: an extraction unit which acquires sensor data from a sensor installed on the footwear, and uses the sensor data to extract a walking feature quantity characteristic of walking in footwear; and an estimation unit which estimates the type of footwear on the basis of the walking feature quantity extracted by the extraction unit.

Abstract: A step width measurement device includes a distance calculation unit that calculates a distance between both feet of a user by using propagation data related to transmission/reception times of ultrasonic waves transmitted/received by ultrasonic transmission/reception devices mounted on each of the both feet of the user, a height calculation unit that calculates a height of a sensor by using sensor data including a spatial acceleration and a spatial angular velocity measured by sensors mounted on each of the both feet of the user, and a step width calculation unit that calculates a step width of the user by using the distance between the both feet measured at the same timing and the height of the sensor.

Abstract: A step width measurement device includes a distance calculation unit that calculates a distance between both feet of a user by using propagation data related to transmission/reception times of ultrasonic waves transmitted/received by ultrasonic transmission/reception devices mounted on each of the both feet of the user, a height calculation unit that calculates a height of a sensor by using sensor data including a spatial acceleration and a spatial angular velocity measured by sensors mounted on each of the both feet of the user, and a step width calculation unit that calculates a step width of the user by using the distance between the both feet measured at the same timing and the height of the sensor.

Abstract: Embodiments described herein relate to systems and methods for controlling sensors, receiving sensor data, and evaluating the interrelationship between breath and movement and providing analysis and feedback to the user through a device. The system generates digital instructions and output for an online web application, device hosted application, smart device, or similar system.

Abstract: The present invention is an improved method for measuring the electromotile movement of outer hair cells (OHC) which are used in assessing the condition of the OHC and the state of the acoustic path of OHC. The obtained measurement results may be further processed either by comparing them to a standard signal obtained from the electromotile movement of OHC of averaging of a large number of measurements from “normative” people or by comparing them to a model. The measuring method: Stimulated OHC emit acoustic and electromagnetic signals as a result of a stimulus. The method of the invention comprises capturing the emitted electromagnetic signals from the OHC by electrodes placed in close vicinity of an ear of a treated person. The captured signals are transmitted, in the form of a wave file, via electrical connections to a signal processor. The signal processor applies spatial averaging and/or voting algorithm(s) and produces measurement results.

Abstract: A system and method of providing an acoustic stimulus for a human subject so as to evoke an auditory response is presented. The method includes creating a chirp signal, wherein creating the chirp signal includes adding a plurality of frequency signals, each frequency signal delayed within the chirp signal based on its associated frequency specific basilar membrane delay determined as a function of measured in vivo frequency specific basilar membrane delays.

Abstract: An illustrative hearing system may include an optical waveguide at least partially positioned within an ear canal of a user and having a sensing region located between a first end and a second end of the optical waveguide. A light source may be configured to emit light into the optical waveguide at the first end, such that a first portion of the light may exit the optical waveguide at the sensing region and be absorbed by cerumen within the ear canal. A detector may be configured to detect a second portion of the light that exits the optical waveguide at the second end. A processing unit may be configured to determine, based on the second portion of the light detected by the detector and the light emitted by the light source, a glucose value representative of a glucose concentration in the cerumen.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: An electronic device comprises at least one sensor configured to acquire a pulse wave on a measured part of a subject, and a controller configured to estimate glucose metabolism of the subject from an index based on the pulse wave acquired by the sensor. The controller estimates the glucose metabolism based on a first index related to a pulse wave acquired at a first time and a second index related to a pulse wave acquired at a second time after the first time.

Abstract: Measuring device (1) intended to be disposed against a medium, the device extending between a contact face (10) intended to be applied facing the medium and a distal end (4), the device including a lateral wall (5) extending between the contact face and the distal end, the device including: at the level of the contact face (10), at least one admission opening (12) configured to collect a transcutaneous gas of interest emitted through the medium, the admission opening being through the contact face; a measuring chamber (20) including a gas sensor (23), the gas sensor being configured to measure a concentration of the gas of interest flowing through the measuring chamber; a collecting chamber (30) connected to the measuring chamber and delimited by an opening on the lateral wall, the collecting chamber including at least one lateral opening (34) through the lateral face or on the top wall of the collecting chamber so as to admit a vector gas into the collecting chamber; the device being characterized in tha

Abstract: There is provided a method of taking pulse oximetry measurements, the method comprising: providing a calibration pulse-oximeter adapted to estimate one or more first, reference SpO2 values from a first, reference PPG signal measured by the pulse-oximeter on a first, reference area of the human body: and, using the same or a different calibration pulse-oximeter, estimating one or more second SpO2 values from a second PPG signal measured by said same or different calibration pulse-oximeter on a second, target area of the human body. At this point, a calibration parameter or calibration function is calculated on the basis of the one or more first, reference SpO2 values and the second SpO2 values. Then, using a measurement pulse-oximeter, a plurality of third SpO2 values is measured from the second PPG signal on the second, target area of the human body and the resulting values are calibrated using said calibration parameter or function.

Abstract: A near-infrared spectroscopy system comprises a substrate, a light source emitting a set of wavelengths, an optical detector detecting the set of wavelengths, a processor in electronic communication with the light source bank and/or the optical detector, and a memory device in electronic communication with the processor. The light source bank, optical detector, processor, and memory device are mounted on the substrate, and a battery is in electronic communication with at least one of these components. Program instructions direct the processor to calculate an oxygenation level, compare that oxygenation level to a predetermined threshold, and optionally, activate a feedback device. A method of detecting an oxygenation level comprises mounting the system in a wearable article, calculating a baseline oxygenation level, regularly executing the program instructions to calculate the oxygenation level, and activating the feedback device.

Abstract: A device for obtaining physiological information of a medical patient and wirelessly transmitting the obtained physiological information to a wireless receiver.

Abstract: A tissue oximeter is provided including a wearable sensor unit including a skin contact detector having at least one electrode configured to provide a detection signal when a contact surface is in contact with the skin of a subject; at least one tunable light source arranged to provide a first and second beam of light at two wavelengths; a photodetector arranged to receive the first beam of light and the second beam of light that are reflect from the tissue of a subject.

Abstract: Method and system for providing continuous calibration of analyte sensors includes calibrating a first sensor, receiving data associated with detected analyte levels from the first sensor, and calibrating a second sensor based on a predetermined scaling factor and data associated with detected analyte levels from the first sensor, is disclosed.

Abstract: A microfluidic device for obtaining a quantity of plasma includes a collection module for blood plasma arranged to passively separate the blood plasma from a drop of blood taken, a capillary channel in fluidic connection with said collection module and a storage chamber for a gas in fluidic connection with said capillary channel. The volume of said storage chamber, after saturation of said capillary channel with blood plasma, entrains the plasma in the capillary channel and causes up to the entire so volume of the plasma in the capillary channel to be ejected from a flow outlet of the capillary channel.

Abstract: A flow restriction device may include a male luer connector portion, a female luer connector portion, and a flexible tube. The male luer connector portion defies a first lumen. The female luer connector portion defines a second lumen. The flexible tube defines a third lumen. The third lumen is in fluid communication with the first lumen and the second lumen. The third lumen has a diameter of about 0.02 inches.

Abstract: The invention provides devices for blood collection that integrate a plurality of microneedles for an easy-to-use, pain-free blood collection experience. The invention provides both plasma and whole blood collection and separation in a single device. The invention provides for the collection, storage, and maintenance of blood specimens for stable transport to diagnostic laboratories, in varying ambient temperatures and time durations. Specifically, the invention provides a blood collection device that allows a user to collect an accurately metered quantity of blood.

Abstract: Provided herein is a blood draw device for use with a PIVC. The blood draw device includes a catheter, an introducer housing, and an actuator movably coupled to the introducer housing. The introducer housing includes a first member and a second member coupled together via a plurality of snaps to define an inner volume configured to movably receive the catheter. A plurality of lower snaps is formed on the first housing member and spaced apart between proximal and distal ends thereof, each of the lower snaps having a hook that is oriented downward. A first upper snap is formed on the first housing member at a distal end thereof, the first upper snap having a hook that is oriented upward. A second upper snap is formed on the second housing member at a proximal end thereof, the second upper snap having a hook that is oriented downward.

Abstract: The present disclosure provides a non-contact fatigue detection system and method based on rPPG. The system and method adopt multi-thread synchronous communication for real-time acquisition and processing of rPPG signal, enabling fatigue status detection. In this setup, the first thread handles real-time rPPG data capture, storage and concatenation, while the second thread conducts real-time analysis and fatigue detection of rPPG data. Through a combination of skin detection and LUV color space conversion, rPPG raw signal extraction is achieved, effectively eliminating interference from internal and external environmental facial noise; Subsequently, an adaptive multi-stage filtering process enhances the signal-to-noise ratio, and a multi-dimensional fusion CNN model ensures accurate detection of respiration and heart rate.

Abstract: Example systems, methods, and apparatus, including cognitive platforms, are provided for applying signal detection metrics in computer-implemented adaptive response-deadline procedures to data collected based at least in part on user interaction(s) with computerized tasks and/or interferences. The apparatus can include a response classifier for generating a quantifier of the cognitive abilities of an individual. The apparatus also can be configured to adapt the tasks and/or interferences to enhance the individual's cognitive abilities.

Abstract: In order to estimate a stress level with higher accuracy than conventional techniques, a stress level estimation method includes: classifying, by at least one processor, measurement data into first measurement data and second measurement data, the measurement data having been measured during a predetermined time period and pertaining to a stress level that indicates a degree of stress of a subject, the first measurement data having been measured during working hours of the subject, and the second measurement data having been measured outside the working hours; and estimating, by the at least one processor, a stress level of the subject using at least one of the first measurement data and the second measurement data.

Abstract: Embodiments disclosed herein are directed to a self-learning bladder volume monitoring system. The system can include a bladder volume (BV) system configured to measure an electrical impedance of a bladder region of a patient and determine a volume of fluid disposed therein using an impedance to bladder volume model (“By model”). Further, the system can measure a total body water (“TBW”) for the patient and modify the BV model to account for variations in TBW within the tissues surrounding the bladder providing a more accurate bladder volume measurement. The system can include a “training unit” which can include one of a user input interface, an automatic urine output monitoring system, an ultrasound system, and an intrabladder pressure system configured to verify a volume of fluid within or voided from the bladder and train the BV model.

Abstract: A biological information measurement device includes a sensor unit and a controller. The sensor unit includes an N number of measurement portions. N is a natural number of 3 or greater. The controller acquires an N number of output signals from the measurement portions in a given acquisition order. The controller outputs a shutdown signal having a first level to the measurement portions in accordance with the acquisition order of the output signals. The controller outputs the shutdown signal having a second level to the measurement portions in response to acquisition of a corresponding output signal. When the controller outputs the first-level shutdown signal to the measurement portion having an ordinal number of i in the acquisition order, where i is a natural number of 1 or greater, the controller also outputs the first-level shutdown signal to the measurement portion having an ordinal number of (i+1) in the acquisition order.

Abstract: An ECG electrode is provided. The ECG electrode includes an electrode substrate and a doped graphite-like carbon film located on an outer surface of the electrode substrate. The doped graphite-like carbon film includes graphite-like carbon, and first nano-crystals and second nano-crystals that are embedded in the graphite-like carbon. The first nano-crystal includes a weak carbon-bonding element. The weak carbon-bonding element has a part that exists in a form of a metallic elementary substance. The first nano-crystal includes a columnar structure. The columnar structure extends in a thickness direction of the doped graphite-like carbon film. The second nano-crystal includes a strong carbon-bonding element. The strong carbon-bonding element bonds with the carbon element in the graphite-like carbon through a chemical bond. The second nano-crystals are distributed between adjacent and spaced columnar structures.

Abstract: A flexible electrode includes a layer of an interpenetrating network of silver nanowires and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), and a core comprising a foam. The layer of interpenetrating network of silver nanowires and PEDOT:PSS are wrapped around the core. A wearable device includes a current source comprising a pair of outer electrodes, and voltage sensors comprising one or two pairs of internal electrodes that are arranged between the outer electrodes. At least one electrode of these electrodes is a flexible electrode.